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1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Hypertension, Pulmonary

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Hypertension, Pulmonary in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19908 (17.39)18.7374
1990's34 (73.91)18.2507
2000's3 (6.52)29.6817
2010's0 (0.00)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Endo, J; Moriyama, H1
Gutbier, B; Ishii, S; Mayer, K; Mitchell, TJ; Owen, JS; Rosseau, S; Schmeck, B; Schütte, H; Suttorp, N; Thomas, MJ; Witzenrath, M1
Chen, H; Wang, H; Wang, YL; Xia, SH; Xu, W1
Hechtman, HB; Shepro, D; Valeri, CR1
Canham, EM; Heffner, JE; McMurtry, IF; Morris, HG; Patel, M; Repine, JE; Shoemaker, SA2
Chen, W; Cheng, D; Yang, X2
Argiolas, L; del Basso, P; Fabi, F1
Endres, S; Kohl, J; Machleidt, W; Siebeck, M; Spannagl, M1
Ma, CT1
Ashino, Y; Fujimura, S; Hoshikawa, Y; Nishimura, T; Noda, M; Ono, S; Tabata, S; Tanita, T; Ueda, S1
Chen, WB; Cheng, DY1
Johnson, LW; Kruse-Elliott, KT; Olson, NC1
Huang, YC; Kennedy, TP; Piantadosi, CA; Su, YF; Watkins, WD; Whorton, AR1
Goldsmith, JA; Kavanagh, BP; Pearl, RG1
Atkinson, J; Berkeland, J; Emil, S; Kosi, M1
Chen, W; Cheng, D3
Belenkov, Yu; Chazova, I; Gabbasov, Z; Nakonechnicov, S; Popov, E1
Chen, D; Chen, W1
Koyama, S; Matsuda, Y; Shibamoto, T; Wang, HG1
Asada, A; Hayashi, M; Inoue, M; Yamada, T; Yukioka, H1
Tuder, RM; Voelkel, NF1
Abu-Zidan, FM; Karlsson, H; Lennquist, S; Walther, S1
Ding, JS; He, JL; Li, HP; Quan, CJ1
Delong, P; Hubbard, CL; Huggins, E; McCall, C; O'Sullivan, MG1
Quinn, JV; Slotman, GJ1
Goldfarb, R1
Carter, MB; Clavijo, LC; Garrison, RN; Matheson, PJ; Wead, WB; Wills-Frank, LA; Wilson, MA1
Ono, S; Voelkel, NF2
Ono, S; Voelkel, NF; Westcott, JY1
Davidson, D; Drafta, D1
Andrew, M; Coles, J; Rabinovitch, M; Trusler, GA; Turner-Gomes, SO; Williams, WG1
DeMello, D; Lagunoff, D; Ohar, JA; Waller, KS1
Davidson, D; Singh, M; Wallace, GF1
Brendel, W; Conzen, PF; Gutmann, R; Habazettl, H; Hobbhahn, J; Peter, K; Vollmar, B; Yekebas, E1
Barnes, PJ; Evans, TW; McCormack, DG1
Hyers, TM; Lagunoff, D; Ohar, JA; Pyle, JA; Waller, KS; Webster, RO1
Gasser, H; Krautschneider, S; Paul, E; Redl, H; Schiesser, A; Schlag, G; Thurnher, M; Vogl, C1
McDonald, JW; Smallbone, BW; Taylor, NE1
Becher, G; Kühn, H; Schewe, T; Schilling, W; Slapke, J1
Imai, T; Jacob, HS; Moldow, CF; Vercellotti, GM; Weir, EK1
Mlczoch, J1

Reviews

6 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Hypertension, Pulmonary

ArticleYear
Pathophysiological Involvement of Mast Cells and the Lipid Mediators in Pulmonary Vascular Remodeling.
    International journal of molecular sciences, 2023, Apr-01, Volume: 24, Issue:7

    Topics: Eicosanoids; Epoxy Compounds; Humans; Hypertension, Pulmonary; Mast Cells; Platelet Activating Factor; Vascular Remodeling

2023
Role of platelet activating factor in pathogenesis of acute respiratory distress syndrome.
    Chinese medical journal, 2007, Oct-20, Volume: 120, Issue:20

    Topics: Animals; Humans; Hypertension, Pulmonary; Inflammation Mediators; Neutrophil Activation; Platelet Activating Factor; Pulmonary Edema; Respiratory Distress Syndrome

2007
Role of humoral mediators in adult respiratory distress syndrome.
    Chest, 1984, Volume: 86, Issue:4

    Topics: Animals; Arachidonic Acids; Chemotaxis, Leukocyte; Chromones; Dogs; Guinea Pigs; Humans; Hypertension, Pulmonary; Inflammation; Ketanserin; Leukocyte Count; Leukocytes; Lung; Piperidines; Platelet Activating Factor; Pulmonary Embolism; Respiratory Distress Syndrome; Serotonin; Serotonin Antagonists; SRS-A; Thromboxane A2

1984
[The current status of the research on platelet activating factor and pulmonary hypertension].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1993, Volume: 16, Issue:1

    Topics: Humans; Hypertension, Pulmonary; Platelet Activating Factor; Pulmonary Circulation

1993
Pulmonary hypertension and inflammation.
    The Journal of laboratory and clinical medicine, 1998, Volume: 132, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Endothelial Growth Factors; Endothelins; Humans; Hypertension, Pulmonary; Inflammation; Insulin-Like Growth Factor I; Lymphokines; Platelet Activating Factor; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1998
Investigations into the polydeterminant nature of sepsis.
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Animals; Arachidonic Acid; Eicosanoids; Heart Diseases; Humans; Hypertension, Pulmonary; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1999

Other Studies

40 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Hypertension, Pulmonary

ArticleYear
Role of platelet-activating factor in pneumolysin-induced acute lung injury.
    Critical care medicine, 2007, Volume: 35, Issue:7

    Topics: Animals; Bacterial Proteins; Disease Models, Animal; Female; Humans; Hypertension, Pulmonary; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pneumonia, Pneumococcal; Protein Serine-Threonine Kinases; Respiratory Distress Syndrome; rho-Associated Kinases; Signal Transduction; Streptolysins; Thromboxane A2

2007
Acetyl glyceryl ether phosphorylcholine-stimulated human platelets cause pulmonary hypertension and edema in isolated rabbit lungs. Role of thromboxane A2.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:2

    Topics: Animals; Blood Platelets; Female; Hypertension, Pulmonary; Imidazoles; Lung; Male; Perfusion; Platelet Activating Factor; Pressure; Prostanoic Acids; Pulmonary Edema; Rabbits; Thromboxane A2

1983
Platelet-induced pulmonary hypertension and edema. A mechanism involving acetyl glyceryl ether phosphorylcholine and thromboxane A2.
    Chest, 1983, Volume: 83, Issue:5 Suppl

    Topics: Albumins; Animals; Blood Platelets; Hypertension, Pulmonary; Lung; Neutrophils; Platelet Activating Factor; Pulmonary Edema; Rabbits; Thromboxane A2; Thromboxanes

1983
[Acute effects of platelet activating factor on the pulmonary circulation in rats].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1995, Volume: 26, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Hypertension, Pulmonary; Male; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar

1995
Mechanisms of pulmonary vasoconstriction and bronchoconstriction produced by PAF in the guinea-pig: role of platelets and cyclo-oxygenase metabolites.
    British journal of pharmacology, 1995, Volume: 114, Issue:1

    Topics: Animals; Blood Platelets; Blood Pressure; Bronchoconstriction; Cardiac Output; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Hypertension, Pulmonary; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats

1995
Delayed treatment with platelet activating factor receptor antagonist web 2086 attenuates pulmonary dysfunction in porcine endotoxin shock.
    The Journal of trauma, 1994, Volume: 37, Issue:5

    Topics: Animals; Azepines; Blood Pressure; Cathepsin B; Creatinine; Extravascular Lung Water; Hypertension, Pulmonary; Lipopolysaccharides; Lung; Platelet Activating Factor; Pulmonary Artery; Pulmonary Gas Exchange; Salmonella; Shock, Septic; Swine; Swine, Miniature; Triazoles; Tumor Necrosis Factor-alpha; Vascular Resistance

1994
[Variation of plasma platelet activating factor during development and reversal of hypoxic pulmonary hypertension in conscious sheep].
    Sheng li xue bao : [Acta physiologica Sinica], 1994, Volume: 46, Issue:4

    Topics: Animals; Female; Hypertension, Pulmonary; Hypoxia; Platelet Activating Factor; Radioimmunoassay; Sheep; Vasoconstriction

1994
[Lung 3H-thymidine incorporation in monocrotaline (MCT)-treated rats--role of platelet-activating factor (PAF)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1994, Volume: 32, Issue:5

    Topics: Animals; Azepines; DNA; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thymidine; Triazoles

1994
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles

1993
Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:1

    Topics: Animals; Arachidonic Acids; Benzoquinones; Blood Pressure; Bronchoconstriction; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indicators and Reagents; Indomethacin; Interferon Inducers; Interferon Type I; Lipoxygenase Inhibitors; Lung Diseases; Male; Microcirculation; Platelet Activating Factor; Poly I-C; Pulmonary Edema; Rabbits; Recombinant Proteins; Vascular Resistance

1993
Plasma potentiates the priming effects of endotoxin on platelet activating factor-induced pulmonary hypertension in the rabbit lung.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:2

    Topics: Acute-Phase Proteins; Animals; Blood Pressure; Blood Proteins; Carrier Proteins; Disease Models, Animal; Endotoxins; Escherichia coli; Hypertension, Pulmonary; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Membrane Glycoproteins; Plasma; Platelet Activating Factor; Pulmonary Artery; Rabbits; Respiratory Distress Syndrome; Serum Albumin

1996
Inhaled nitric oxide prevents experimental platelet activating factor-induced shock.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:8

    Topics: Administration, Inhalation; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Platelet Activating Factor; Random Allocation; Shock, Septic; Swine

1996
[Effects of ginkgolide B on isobaric hypoxic pulmonary hypertension in rats].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1995, Volume: 26, Issue:4

    Topics: Animals; Diterpenes; Ginkgolides; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar

1995
Platelet aggregation in patients with primary pulmonary hypertension.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:2

    Topics: Adenosine Diphosphate; Blood Platelets; Humans; Hypertension, Pulmonary; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prognosis

1996
Changes of distribution of platelet activating factor in the lung of rats with hypoxic pulmonary hypertension.
    Chinese medical journal, 1996, Volume: 109, Issue:10

    Topics: Animals; Arterioles; Hypertension, Pulmonary; Hypoxia; Lung; Male; Platelet Activating Factor; Pulmonary Alveoli; Rats; Rats, Wistar

1996
Effects of ginkgolide B on isobaric hypoxic pulmonary hypertension in rats.
    Chinese medical journal, 1996, Volume: 109, Issue:11

    Topics: Animals; Arterioles; Diterpenes; Ginkgolides; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lactones; Lung; Male; Platelet Activating Factor; Rats; Rats, Wistar

1996
[The level of platelet activating factor in blood of rats with hypoxic pulmonary hypertension].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1996, Volume: 27, Issue:2

    Topics: Animals; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Platelet Activating Factor; Rats; Rats, Wistar

1996
[The role of platelet activating factor in chronic pulmonary hypertension].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1996, Volume: 27, Issue:3

    Topics: Animals; Arterioles; Blood Pressure; Hypertension, Pulmonary; Lung; Male; Platelet Activating Factor; Pulmonary Artery; Rats; Rats, Wistar; Vascular Resistance

1996
The role of endogenous nitric oxide in the sympathetic and hemodynamic response to platelet activating factor-induced hypotension in anesthetized dogs.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:1

    Topics: Anesthetics; Animals; Blood Gas Analysis; Blood Pressure; Dogs; Enzyme Inhibitors; Female; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Sympathetic Nervous System; Vasomotor System

1998
Effects of inhaled nitric oxide on platelet-activating factor-induced pulmonary hypertension in dogs.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Hemoglobins; Hypertension, Pulmonary; Injections, Intravenous; Methemoglobin; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxygen; Platelet Activating Factor; Pulmonary Circulation; Vasoconstrictor Agents

1998
Heparin ameliorates pulmonary hypertension induced by platelet-activating factor in pigs.
    Thrombosis research, 1998, Jun-01, Volume: 90, Issue:5

    Topics: Animals; Anticoagulants; Drug Antagonism; Female; Heparin; Hypertension, Pulmonary; Injections, Intravenous; Male; Platelet Activating Factor; Swine

1998
[The relationship between the activity of phospholipase A2 and acute hypoxic pulmonary arterial pressure].
    Sheng li xue bao : [Acta physiologica Sinica], 1997, Volume: 49, Issue:6

    Topics: Animals; Dinoprostone; Female; Hypertension, Pulmonary; Hypoxia; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane B2

1997
Bacterial lipopolysaccharide induction of the prostaglandin G/H synthase 2 gene causes thromboxane-dependent pulmonary hypertension in rabbits.
    American journal of respiratory cell and molecular biology, 1999, Volume: 20, Issue:3

    Topics: Animals; Arachidonic Acid; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dactinomycin; Drug Interactions; Enzyme Induction; Female; Hypertension, Pulmonary; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Perfusion; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; Thromboxanes

1999
Platelet-activating factor and arachidonic acid metabolites mediate tumor necrosis factor and eicosanoid kinetics and cardiopulmonary dysfunction during bacteremic shock.
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Aeromonas hydrophila; Animals; Arachidonic Acid; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Eicosanoids; Female; Gram-Negative Bacterial Infections; Heart Diseases; Hemodynamics; Hypertension, Pulmonary; Lipoxygenase Inhibitors; Masoprocol; Oxazoles; Oxygen; Oxygen Consumption; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Swine; Thromboxane A2; Triazoles; Tumor Necrosis Factor-alpha

1999
Platelet-activating factor and bacteremia-induced pulmonary hypertension.
    The Journal of surgical research, 2000, Volume: 88, Issue:2

    Topics: Animals; Bacteremia; Endothelin-1; Escherichia coli Infections; Hemodynamics; Hemoglobins; Hypertension, Pulmonary; Male; Neutrophils; Nitric Oxide; Oxygen; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

2000
PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model.
    Lung, 1992, Volume: 170, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Hydroxyproline; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Artery; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thymidine; Triazoles

1992
PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:3

    Topics: Animals; Azepines; Endothelins; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Circulation; Rats; Triazoles; Vasoconstriction

1992
Prolonged pulmonary hypertension caused by platelet-activating factor and leukotriene C4 in the rat lung.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Diethylcarbamazine; Hypertension, Pulmonary; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Male; Perfusion; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; SRS-A

1992
Abnormalities in von Willebrand factor and antithrombin III after cardiopulmonary bypass operations for congenital heart disease.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 103, Issue:1

    Topics: Antithrombin III; Cardiopulmonary Bypass; Child; Follow-Up Studies; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Platelet Activating Factor; Postoperative Complications; Protein C; Pulmonary Embolism; von Willebrand Factor

1992
Administration of chronic intravenous platelet-activating factor induces pulmonary arterial atrophy and hypertension in rabbits.
    Laboratory investigation; a journal of technical methods and pathology, 1991, Volume: 65, Issue:4

    Topics: Animals; Atrophy; Cardiomegaly; Hemodynamics; Hypertension, Pulmonary; Infusions, Intravenous; Lung; Platelet Activating Factor; Pulmonary Artery; Rabbits

1991
PAF antagonists inhibit monocrotaline-induced lung injury and pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:6

    Topics: Animals; Azepines; Cardiomegaly; Hypertension, Pulmonary; Lung; Lung Injury; Male; Monocrotaline; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles

1991
Role of leukotriene C4 in pulmonary hypertension: platelet-activating factor vs. hypoxia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:4

    Topics: Animals; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Hypoxia; Indomethacin; Kinetics; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A

1990
Pulmonary hypertension after heparin-protamine: roles of left-sided infusion, histamine, and platelet-activating factor.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:6

    Topics: Animals; Azepines; Clemastine; Hemodynamics; Heparin Antagonists; Hypertension, Pulmonary; Platelet Activating Factor; Protamines; Ranitidine; Swine; Triazoles

1990
Platelet-activating factor: evidence against a role in hypoxic pulmonary vasoconstriction.
    Critical care medicine, 1990, Volume: 18, Issue:12

    Topics: Animals; Azepines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Male; Platelet Activating Factor; Pulmonary Circulation; Swine; Triazoles; Vascular Resistance; Vasoconstriction

1990
A rabbit model of pulmonary hypertension induced by the synthetic platelet-activating factor acetylglyceryl ether phosphorylcholine.
    The American review of respiratory disease, 1990, Volume: 141, Issue:1

    Topics: Animals; Blood Cell Count; Body Weight; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Extravascular Lung Water; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Platelet Activating Factor; Platelet Aggregation; Pulmonary Alveoli; Pulmonary Artery; Rabbits

1990
Effect of platelet-activating factor (PAF) administration in chronically instrumented sheep--analysis of PAF in plasma.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Blood Pressure; Cardiac Output; Chromatography, High Pressure Liquid; Hypertension, Pulmonary; Lung; Lymph; Platelet Activating Factor; Sheep; Vascular Resistance

1989
Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Animals; Aspirin; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Endotoxins; Female; Furans; Hypertension, Pulmonary; Hypoxia; Neutropenia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sheep; Thromboxanes; Zymosan

1987
[Test hierarchy for the development of new drug action principles with the action site in phospholipid metabolism for bronchial asthma and pulmonary hypertension].
    Praxis und Klinik der Pneumologie, 1988, Volume: 42 Suppl 1

    Topics: Animals; Arachidonic Acids; Asthma; Disease Models, Animal; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Hypertension, Pulmonary; Lipoxygenase Inhibitors; Platelet Activating Factor; Pulmonary Artery; Rabbits

1988
Pulmonary hypertension and edema induced by platelet-activating factor in isolated, perfused rat lungs are blocked by BN52021.
    The Journal of laboratory and clinical medicine, 1988, Volume: 111, Issue:2

    Topics: Animals; Diterpenes; Edema; Furans; Ginkgolides; Hypertension, Pulmonary; Injections, Intra-Arterial; Lactones; Lung; Male; Organ Size; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred Strains

1988
[Disorders of thrombocyte function and/or endothelial cell damage as a cause of primary pulmonary hypertension?].
    Herz, 1986, Volume: 11, Issue:4

    Topics: Animals; Blood Platelets; Endothelium; Epoprostenol; Fibrinolysis; Humans; Hypertension, Pulmonary; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pulmonary Artery

1986