Compounds > 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
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1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Endotoxin Shock

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Endotoxin Shock in 132 studies

Research

Studies (132)

TimeframeStudies, this research(%)All Research%
pre-199030 (22.73)18.7374
1990's89 (67.42)18.2507
2000's13 (9.85)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, JH; Chun, SH; Jeong, SK; Jeong, YI; Jung, ID; Kang, MS; Lee, CM; Lee, JD; Lee, SY; Lee, WS; Noh, KT; Park, YM; Shin, YK1
Ishii, S; Nagase, T; Shimizu, T1
Bozza, FA; Bozza, M; Bozza, PT; Castro-Faria-Neto, HC; Gomes, RN; Pacheco, P; Weller, PF1
Fegbeutel, C; Gokorsch, S; Grimminger, F; Hattar, K; Heuer, KU; Krämer, HJ; Mayer, K; Seeger, W; Sibelius, U; Temmesfeld-Wollbrück, B1
Adachi, Y; Kurihara, K; Nagi-Miura, N; Ohno, N; Shingo, Y; Suzuki, K1
Kalter, ES1
Okano, S; Tagawa, M; Urakawa, N3
Banba, N; Kasai, K; Nakamura, T; Sekiguchi, Y; Shimoda, S; Suzuki, Y; Takekoshi, K1
Adams, JL; Badger, A; Bolognese, B; Chabot-Fletcher, M; Flamberg, PL; Hall, RH; Marshall, LA; Roshak, A; Sung, CM; Winkler, JD1
Abu-Zidan, FM; Lennquist, S; Walther, S2
Kirkpatrick, CJ; Klinge, U; Klosterhalfen, B; Mittermayer, C; Schumpelick, V; Töns, C1
Kald, B; Lindahl, M; Sörensen, J; Tagesson, C1
Albert, DH; Carter, GW; Conway, RG; Davidsen, SK; Holms, JH; Luo, G; Magoc, TJ; Rhein, DA; Summers, JB; Tapang, P1
Buripakdi, D; Karlstad, MD1
Guinot, P1
Albert, DH; Summers, JB1
Chiapparino, C; Foresta, P; Manganello, S; Martelli, EA; Pacello, L; Ruggiero, V1
Ji, Z; Li, S; Wang, B1
Braquet, P; Koltai, M; Pirotzky, E1
Crawford, SE; Hsueh, W; Huang, L; Tan, X1
Karasawa, K; Kato, H; Nojima, S; Setaka, M1
Brunet, F; Dhainaut, JF; Mira, JP1
Caplan, MS; Hsueh, W; Liu, Y; Sun, X1
Fujiwara, S; Kawamura, M; Kitayoshi, T; Nishikawa, K; Takatani, M; Terashita, Z1
Braquet, PG; Hosford, D; Koltai, M1
Endres, S; Kohl, J; Machleidt, W; Siebeck, M; Spannagl, M1
Chen, XS; Funk, CD; Johnson, EN; Sheller, JR1
Caplan, MS; Fracica, PJ; Griebel, JA; Huang, YT; Piantadosi, CA; Simonson, SG; Welty-Wolf, K1
Autore, G; Capasso, F; Cicala, C; Cirino, G; Maiello, FM; Mascolo, N1
Braquet, PG; Guinot, P; Hosford, D; Koltai, M1
Bouman, AA; Mulder, MF; Scheffer, PG; Thijs, LG; van den Bos, GC; van Kraats, AA; van Lambalgen, AA1
Fletcher, JR1
Bachy, A; Fraisse, L; Herbert, JM; Keane, PE; Lale, A; Laplace, MC; Lassalle, J; Roche, B; Savi, P; Valette, G1
Iwao, H; Kim, S; Miura, K; Yamanaka, S; Yukimura, T1
Boruff, JS; Karlstad, MD1
Baba, S; Muro, H; Nakamura, S; Onuki, Y1
Kamochi, M; Koga, K; Matsumoto, T; Ogata, M; Sata, T; Shigematsu, A; Takenaka, I; Yoshida, S1
Ben-Efraim, S; Bonta, IL; Heiligers, JP; Mózes, T; Saxena, PR; Tak, CJ; Zijlstra, FJ3
Aosasa, S; Kinoshita, M; Mochizuki, H; Oda, Y; Ohe, H; Ohkusa, Y; Ono, S; Tamakuma, S1
Calvello, C; Klabunde, RE1
Howard, KM; Mustafa, SB; Olson, MS1
Atkinson, J; Berkeland, J; Emil, S; Kosi, M1
De Kimpe, SJ; Thiemermann, C; Vane, JR1
Albert, DH; Carter, GW; Grossman, JE; Kruse-Elliott, KT; Summers, JB; Zimmerman, JJ1
Puglisi, RN; Quinn, JV; Slotman, GJ; Woolley, DS1
Arakawa, N; Endo, S; Inada, K; Nakae, H; Ogawa, M; Shimamura, T; Suzuki, T; Takakuwa, T; Taniguchi, S; Teraoka, H; Yaegashi, Y; Yamada, Y1
Ebara, T; Imanishi, M; Iwao, H; Kim, S; Matsuura, T; Miura, K; Yamano, Y1
Frasa, H; Hoepelman, AI; Hustinx, WM; Verhoef, J1
Giles, TD; Greenberg, SS; Powers, DR; Xie, J1
Ikuta, K; Ishii, S; Kume, K; Miyazaki, J; Nagase, T; Sato, S; Shimizu, T; Tashiro, F; Waga, I1
Fujii, N; Hayashi, S; Hirose, K; Isogai, E; Isogai, H; Kimura, K; Kubota, T1
Balsa, D; Ferrando, R; Forn, J; Garcia-Rafanell, J; Giral, M; Merlos, M1
Mysiakin, EB; Shebzukhov, IuV; Vaĭsburd, MIu; Zaĭtseva, LG1
Smail, N; Spapen, H; Verhaeghe, V; Vincent, JL; Zhang, H1
Ishii, S; Shimizu, T1
Brause, JE; Devereux, RB; Grobmyer, SR; Hafner, A; Hahn, RT; Nathan, CF; Nicholson, SC; Potter, S1
Quinn, JV; Slotman, GJ1
Goldfarb, R1
Connolly, AB; Vernon, DR1
Buurman, WA; Froon, AH; Greve, JW; Poeze, M; Ramsay, G1
Buripakdi, D; Carroll, RC; Karlstad, MD1
Mysyakin, E; Shaposhnikova, G; Vaisburd, M; Zaitseva, L1
DePlaen, I; Hsueh, W; Liu, X; Rozenfeld, RA1
Camussi, G; Guida, G; Mariano, F; Tetta, C; Triolo, G1
Añel, RL; Kumar, A1
Tibiriçá, E1
Braquet, P; Hosford, D; Koltai, M1
Fumarola, D; Pece, S1
Goto, F; Yoshikawa, D2
Chang, SW1
Donigi-Gale, D; Hogaboam, CM; Shoupe, TS; Wallace, JL1
Feuerstein, G; Lynch, KM; Ohlstein, EH; Poyser, R; Rabinovici, R; Sellers, TS; Slivjak, MJ; Smith, EF; Sulpizio, A; Yue, TL1
Ben-Efraim, S; Bonta, IL; Mozes, T1
Weinberg, JR1
Bone, RC1
Flohé, S; Heinrich, PC; Hörstmann-Jungemann, K; Kirkpatrick, CJ; Klosterhalfen, B; Offner, F; Vogel, P1
Schaller, MD1
Imura, Y; Kawamura, M; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S1
Herbert, JM; Lespy, L; Maffrand, JP1
Feuerstein, G; Rabinovici, R; Vernick, J; Yue, TL1
Braquet, P; Buéno, L; Droy-Lefaix, MT; Pons, L1
Heuer, HO1
Carter, EA; Schiffrin, EJ; Schroeder, S; Trop, M1
Anderson, BO; Bensard, DD; Harken, AH1
Buurman, WA; Engelberts, I; van der Linden, CJ; von Asmuth, EJ1
Fei, X; Gong, XQ; Li, SH; Wu, ZL1
Keser, C; Kohl, J; Machleidt, W; Schweiberer, L; Siebeck, M; Spannagl, M; Weipert, J1
Hara, A; Ikeda, M; Kaneko, H; Shiba, T; Takeuchi, S; Yoshida, H1
Oda, M; Saito, K; Satouchi, K1
Myers, AK; Price, RM; Robey, JW1
Heuer, HO; Letts, G; Meade, CJ1
Bahrami, S; Paul, E; Redl, H; Schiesser, A; Schlag, G; Thurnher, M; Vogl, C2
DiSimone, AG; Earnest, MA; Fletcher, JR1
Caplan, MS; Hsueh, W1
Esser, KM; Farhat, M; Feuerstein, G; Rabinovici, R; Slivjak, M; Smith, EF; Yue, TL1
Ferguson-Chanowitz, KM; Kaplan, JB; Katocs, AS; Kerwar, SS; Oronsky, AL; Pickett, WC; Sass, PM1
Jones, SB; Qi, M1
Hsueh, W; Sun, XM; Torre-Amione, G1
Hemmi, K; Okamoto, M; Shimazaki, N; Yoshida, K1
Pacitti, N; Parratt, JR; Rodger, IW1
Boughton-Smith, NK; Hutcheson, I; Whittle, BJ1
Adam, A; Bourdon, V; Damas, J; Remacle-Volon, G1
Cheng, SF; Fei, X; Li, SH; Wu, ZL1
Makino, S1
Braquet, P; Hosford, D1
Casals-Stenzel, J; Heuer, H1
Ibbotson, GC; Wallace, JL1
Bonavida, B; Braquet, P; Hosford, D; Paubert-Braquet, M1
Bahr, T; Becker, K; Förster, W; Grupe, R; Lueddeckens, G; Schaper, U; Scheuch, DW1
Bessin, P; Braquet, P; Paubert-Braquet, M; Vargaftig, BB1
Imura, Y; Nishikawa, K; Sumida, S; Terashita, Z2
Faden, AI; McIntosh, TK1
Bahr, T; Becker, K; Förster, W; Göres, E; Grupe, R; Lueddeckens, G; Schaper, U; Scheuch, DW1
Lagente, V; Steel, G; Vargaftig, B; Wallace, JL; Whittle, BJ1
Steel, G; Wallace, JL; Whittle, BJ1
Braquet, P; Clostre, F; Etienne, A; Hecquet, F; Soulard, C; Spinnewyn, B1
Adnot, S; Braquet, P; Lefort, J; Vargaftig, BB1
Casals-Stenzel, J1
Braquet, P; Etienne, A; Guilmard, C; Hecquet, F; Soulard, C1
Kobayashi, T; Kubo, K; Kusama, S; Toyofuku, T1
Bessin, P1
Adnot, S; Braquet, P; Lagente, V; Lefort, J; Vargaftig, BB1
Braquet, P; Clostre, F; Etienne, A; Hecquet, F; Soulard, C; Touvay, C1
Mikulaschek, AW; Toth, PD1

Reviews

28 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Endotoxin Shock

ArticleYear
Platelet-activating factor receptor.
    Prostaglandins & other lipid mediators, 2002, Volume: 68-69

    Topics: Animals; Brain; Humans; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Signal Transduction; Skin

2002
Inflammatory mediators and acute infections.
    Resuscitation, 1984, Volume: 11, Issue:3-4

    Topics: Arachidonic Acid; Arachidonic Acids; Complement Activation; Factor XII; Histamine; Humans; Infections; Inflammation; Neutrophils; Platelet Activating Factor; Receptors, Histamine H1; Receptors, Histamine H2; Shock, Septic

1984
Clinical experience with platelet-activating factor antagonists. Past, present, and near future.
    Clinical reviews in allergy, 1994,Winter, Volume: 12, Issue:4

    Topics: Animals; Azepines; Clinical Trials as Topic; Graft Rejection; Humans; Kidney Transplantation; Lactones; Plant Extracts; Platelet Activating Factor; Randomized Controlled Trials as Topic; Shock, Septic; Thienopyridines; Triazoles

1994
Platelet activating factor antagonists.
    Advances in pharmacology (San Diego, Calif.), 1995, Volume: 32

    Topics: Animals; Asthma; Humans; Ischemia; Models, Biological; Pancreatitis; Platelet Activating Factor; Reperfusion Injury; Shock, Septic

1995
PAF-cytokine autocatalytic feed-back network in septic shock: involvement in acute renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9 Suppl 4

    Topics: Acute Kidney Injury; Animals; Azepines; Cytokines; Diterpenes; Down-Regulation; Feedback; Ginkgolides; Humans; Lactones; Lipopolysaccharides; Platelet Activating Factor; Shock, Septic; Triazoles

1994
Platelet-activating factor antagonists as therapeutic strategy in sepsis.
    Progress in clinical and biological research, 1994, Volume: 388

    Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Humans; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis; Shock, Septic

1994
Platelet-activating factor in septic shock.
    New horizons (Baltimore, Md.), 1993, Volume: 1, Issue:1

    Topics: Animals; Disease Models, Animal; Humans; Platelet Activating Factor; Rabbits; Rats; Shock, Septic

1993
Platelet-activating factor antagonists: scientific background and possible clinical applications.
    Advances in pharmacology (San Diego, Calif.), 1994, Volume: 28

    Topics: Animals; Antibodies, Monoclonal; Brain Ischemia; Bronchoconstriction; Humans; Inflammation; Lipopolysaccharides; Myocardial Ischemia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic

1994
Eicosanoids. Critical agents in the physiological process and cellular injury.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Eicosanoids; Gastrointestinal Diseases; General Surgery; Humans; Lipoxygenase; Molecular Biology; Phospholipids; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Tumor Necrosis Factor-alpha

1993
Issues in the adjunct therapy of severe sepsis.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cytokines; Endotoxins; Gram-Negative Bacterial Infections; Humans; Interleukin-6; Nitric Oxide; Platelet Activating Factor; Receptors, Interleukin-1; Shock, Septic; Tumor Necrosis Factor-alpha

1996
[Platelet-activating factor (PAF) receptor-related pathophysiology].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1999, Volume: 44, Issue:8 Suppl

    Topics: Anaphylaxis; Animals; Humans; Mice; Mice, Knockout; Mice, Transgenic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reproduction; Shock, Septic

1999
Investigations into the polydeterminant nature of sepsis.
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Animals; Arachidonic Acid; Eicosanoids; Heart Diseases; Humans; Hypertension, Pulmonary; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1999
Manipulations of the metabolic response for management of patients with severe surgical illness: review.
    World journal of surgery, 2000, Volume: 24, Issue:6

    Topics: Animals; Growth Substances; Humans; Nutritional Support; Platelet Activating Factor; Sepsis; Shock, Septic; Stress, Physiological; Surgical Procedures, Operative; Tumor Necrosis Factor-alpha; Wounds and Injuries

2000
Experimental and emerging therapies for sepsis and septic shock.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:8

    Topics: Animals; Caspase Inhibitors; Complement System Proteins; Enzyme Inhibitors; Fibrinolytic Agents; Humans; Nitric Oxide Synthase; Platelet Activating Factor; Sepsis; Shock, Septic; Steroids

2001
Cardiovascular properties of yangambin, a lignan isolated from Brazilian plants.
    Cardiovascular drug reviews, 2001,Winter, Volume: 19, Issue:4

    Topics: Anaphylaxis; Animals; Blood Platelets; Cardiovascular Agents; Furans; Hemodynamics; In Vitro Techniques; Lignans; Plant Extracts; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Stereoisomerism

2001
Fever, cytokines and shock.
    The Central African journal of medicine, 1992, Volume: 38, Issue:3

    Topics: Cytokines; Fever; Humans; Leukotrienes; Lipopolysaccharides; Platelet Activating Factor; Prostaglandins; Shock, Septic

1992
Phospholipids and their inhibitors: a critical evaluation of their role in the treatment of sepsis.
    Critical care medicine, 1992, Volume: 20, Issue:6

    Topics: Animals; Cyclooxygenase Inhibitors; Humans; Leukotriene Antagonists; Phospholipids; Platelet Activating Factor; Prostaglandins, Synthetic; Sepsis; Shock, Septic; Thromboxane A2

1992
[Sepsis syndrome: progress and therapeutic perspectives].
    Schweizerische medizinische Wochenschrift, 1992, May-16, Volume: 122, Issue:20

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antioxidants; Cardiotonic Agents; Combined Modality Therapy; Critical Care; Cytokines; Drug Therapy, Combination; Fluid Therapy; Humans; Platelet Activating Factor; Retrospective Studies; Shock, Septic

1992
PAF and TNF alpha interactions in the pathophysiology of septic shock.
    Advances in experimental medicine and biology, 1991, Volume: 314

    Topics: Animals; Drug Interactions; Endotoxins; Erythrocytes; Humans; Macrophages; Models, Biological; Platelet Activating Factor; Respiratory Distress Syndrome; Shock, Septic; Tumor Necrosis Factor-alpha

1991
Involvement of platelet-activating factor (PAF) in septic shock and priming as indicated by the effect of hetrazepinoic PAF antagonists.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Azepines; Endotoxins; Humans; Models, Biological; Multiple Organ Failure; Platelet Activating Factor; Shock, Septic; Triazoles

1991
The role of platelet activating factor and its antagonists in shock, sepsis and multiple organ failure.
    Surgery, gynecology & obstetrics, 1991, Volume: 172, Issue:5

    Topics: Animals; Chemotaxis, Leukocyte; Humans; Kidney; Multiple Organ Failure; Myocardial Reperfusion Injury; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic

1991
Necrotizing enterocolitis: role of platelet activating factor, endotoxin, and tumor necrosis factor.
    The Journal of pediatrics, 1990, Volume: 117, Issue:1 Pt 2

    Topics: Animals; Disease Models, Animal; Eicosanoids; Endotoxins; Enterocolitis, Pseudomembranous; Free Radicals; Norepinephrine; Oxygen; Platelet Activating Factor; Rats; Shock, Septic; Tumor Necrosis Factor-alpha

1990
PAF inhibitors of microbial origin. Studies on diketopiperazine derivatives.
    Progress in biochemical pharmacology, 1988, Volume: 22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Chemical Phenomena; Chemistry; Gliotoxin; Hypersensitivity; In Vitro Techniques; Indoles; Nephrosis; Piperazines; Platelet Activating Factor; Rabbits; Shock, Septic

1988
Mediators of acute lung injury in endotoxaemia.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cats; Cyclooxygenase Inhibitors; Endotoxins; Escherichia coli; Lung; Lung Diseases; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Thromboxane-A Synthase; Thromboxanes

1989
[Platelet-activating factor and disease].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:2

    Topics: Anaphylaxis; Animals; Asthma; Capillary Permeability; Humans; Muscle Contraction; Platelet Activating Factor; Platelet Aggregation; Shock, Septic

1989
The potential role of platelet-activating factor (PAF) in shock, sepsis and adult respiratory distress syndrome (ARDS).
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Brain; Burns; Digestive System; Endotoxins; Humans; Kidney; Lung; Platelet Activating Factor; Respiratory Distress Syndrome; Sepsis; Shock, Septic; Shock, Traumatic

1989
Platelet-activating factor: a potential mediator of shock.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B

    Topics: Animals; Disease Models, Animal; Immunoglobulin G; Platelet Activating Factor; Shock; Shock, Septic

1987
Thyrotropin-releasing hormone (TRH) and circulatory shock.
    Circulatory shock, 1986, Volume: 18, Issue:3

    Topics: Anaphylaxis; Animals; Brain; Cardiovascular System; Cats; Endorphins; Guinea Pigs; Hypotension; Lipoxygenase Inhibitors; Platelet Activating Factor; Rats; Shock; Shock, Hemorrhagic; Shock, Septic; SRS-A; Thyrotropin-Releasing Hormone

1986

Trials

2 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Endotoxin Shock

ArticleYear
Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation.
    Intensive care medicine, 2003, Volume: 29, Issue:9

    Topics: Adult; Aged; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Fish Oils; Humans; Leukotrienes; Male; Middle Aged; Neutrophils; Phosphatidylinositols; Pilot Projects; Platelet Activating Factor; Shock, Septic; Superoxides; Thromboxanes

2003
Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:4

    Topics: Adult; Aged; APACHE; Double-Blind Method; Female; Humans; Inflammation Mediators; Isoquinolines; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Shock, Septic; Systemic Inflammatory Response Syndrome; Tetrahydroisoquinolines

2000

Other Studies

102 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Endotoxin Shock

ArticleYear
The novel role of platelet-activating factor in protecting mice against lipopolysaccharide-induced endotoxic shock.
    PloS one, 2009, Aug-04, Volume: 4, Issue:8

    Topics: Animals; Apoptosis; Inflammation Mediators; Lipopolysaccharides; Lymphocytes; Mice; Platelet Activating Factor; Shock, Septic

2009
Lipopolysaccharide-induced leukocyte lipid body formation in vivo: innate immunity elicited intracellular Loci involved in eicosanoid metabolism.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Dec-01, Volume: 169, Issue:11

    Topics: Adult; Animals; Arachidonate 5-Lipoxygenase; Case-Control Studies; Cyclooxygenase 2; Eicosanoids; Female; Humans; Inclusion Bodies; Inflammation Mediators; Isoenzymes; Leukocytes; Lipid Metabolism; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Middle Aged; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sepsis; Shock, Septic; Signal Transduction; Tumor Necrosis Factor-alpha

2002
Involvement of platelet activating factor, histamine and serotonin in acute lethal shock induced by Candida albicans water-soluble extracellular polysaccharide fraction (CAWS) in mice.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:7

    Topics: Acute Disease; Animals; Candida albicans; Capillary Permeability; Epinephrine; Histamine; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Platelet Activating Factor; Polysaccharides; Serotonin; Shock, Septic; Vasculitis

2007
Effect of TCV-309, a novel platelet activating factor antagonist, on hemodynamics in dogs with endotoxin-induced shock.
    The Journal of veterinary medical science, 1995, Volume: 57, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Endotoxins; Escherichia coli; Heart Rate; Hemodynamics; Isoquinolines; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Stroke Volume; Tetrahydroisoquinolines; Vascular Resistance

1995
Effect of NG-nitro-L-arginine on shock induced by endotoxin and by platelet activating factor in dogs.
    European journal of pharmacology, 1993, Dec-21, Volume: 250, Issue:3

    Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Dogs; Endothelium, Vascular; Endotoxins; Female; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Shock; Shock, Septic

1993
SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Arachidonic Acid; Cell-Free System; Disease Models, Animal; Enzyme Inhibitors; Humans; Leukotriene B4; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic; Sulfonamides; Survivors

1995
Modulation of lung injury by platelet-activating factor antagonism in nonhypotensive porcine endotoxemia.
    Circulatory shock, 1994, Volume: 44, Issue:3

    Topics: Animals; Escherichia coli; Female; Leucine; Lipopolysaccharides; Lung; Lung Diseases; Male; Platelet Activating Factor; Shock, Septic; Swine; Vascular Resistance

1994
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].
    Langenbecks Archiv fur Chirurgie, 1993, Volume: 378, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Critical Care; Epoprostenol; Escherichia coli Infections; Hemodynamics; Interleukin-6; Intestinal Mucosa; Intestines; Ion Channels; Ischemia; Lung; Microscopy, Electron; Multiple Organ Failure; Platelet Activating Factor; Postoperative Complications; Potassium; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Shock, Septic; Swine; Thromboxane A2; Tumor Necrosis Factor-alpha

1993
Platelet-activating factor and phospholipase A2 in patients with septic shock and trauma.
    Intensive care medicine, 1994, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bronchoalveolar Lavage Fluid; Case-Control Studies; Female; Humans; Male; Middle Aged; Multiple Trauma; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prognosis; Prospective Studies; Shock, Septic

1994
ABT-299, a potent antagonist of platelet activating factor.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Animals; Binding, Competitive; Blood Pressure; Edema; Esterases; Humans; Hypotension; Indoles; Kinetics; Lipopolysaccharides; Mice; Molecular Structure; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Thiazoles

1995
The role of platelet-activating factor in alterations of system A amino acid transport in rat soleus and extensor digitorum longus muscles during endotoxic shock.
    Shock (Augusta, Ga.), 1994, Volume: 2, Issue:1

    Topics: Amino Acids; Animals; Biological Transport; Male; Muscle, Skeletal; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Salmonella Infections, Animal; Shock, Septic

1994
Effect of platelet activating factor antagonist (CV-3988) on 6-keto-PGF1 alpha and thromboxane B2 in dogs with experimental endotoxin-induced shock.
    The Journal of veterinary medical science, 1995, Volume: 57, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dog Diseases; Dogs; Hemodynamics; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic; Thromboxane B2

1995
Beneficial effects of a novel platelet-activating factor receptor antagonist, ST 899, on endotoxin-induced shock in mice.
    Shock (Augusta, Ga.), 1994, Volume: 2, Issue:4

    Topics: Animals; Biological Assay; Butyrates; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quaternary Ammonium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Time Factors; Tumor Necrosis Factor-alpha

1994
[The role of platelet activating factor in mesenterioangial microcirculatory disturbance complicated with acute pancreatitis in rats].
    Zhonghua yi xue za zhi, 1995, Volume: 75, Issue:3

    Topics: Acute Disease; Animals; Diterpenes; Ginkgolides; Lactones; Male; Microcirculation; Pancreatitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Taurocholic Acid

1995
Platelet-activating factor and endotoxin induce tumour necrosis factor gene expression in rat intestine and liver.
    Immunology, 1994, Volume: 83, Issue:1

    Topics: Animals; Blotting, Northern; Drug Synergism; Gene Expression Regulation; Intestine, Small; Lipopolysaccharides; Liver; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shock, Septic; Tumor Necrosis Factor-alpha

1994
Accumulation of platelet-activating factor acetylhydrolase in the peritoneal cavity of guinea pig after endotoxin shock.
    Journal of biochemistry, 1994, Volume: 116, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Cytosol; Escherichia coli; Exudates and Transudates; Guinea Pigs; Injections, Intraperitoneal; Lipopolysaccharides; Male; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic; Tissue Distribution

1994
Endotoxin-resistant mice are protected from PAF-induced bowel injury and death. Role of TNF, complement activation, and endogenous PAF production.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:3

    Topics: Animals; Complement Activation; Endotoxins; Intestine, Small; Male; Mice; Mice, Inbred C3H; Necrosis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1995
Effects of TCV-309, a novel PAF antagonist, on circulatory shock and hematological abnormality induced by endotoxin in dogs.
    Journal of lipid mediators and cell signalling, 1994, Volume: 9, Issue:3

    Topics: Animals; Blood Circulation; Blood Pressure; Disease Models, Animal; Dogs; Heart; Hematologic Diseases; Hemodynamics; Isoquinolines; Male; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines; Time Factors

1994
Delayed treatment with platelet activating factor receptor antagonist web 2086 attenuates pulmonary dysfunction in porcine endotoxin shock.
    The Journal of trauma, 1994, Volume: 37, Issue:5

    Topics: Animals; Azepines; Blood Pressure; Cathepsin B; Creatinine; Extravascular Lung Water; Hypertension, Pulmonary; Lipopolysaccharides; Lung; Platelet Activating Factor; Pulmonary Artery; Pulmonary Gas Exchange; Salmonella; Shock, Septic; Swine; Swine, Miniature; Triazoles; Tumor Necrosis Factor-alpha; Vascular Resistance

1994
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.
    Nature, 1994, Nov-10, Volume: 372, Issue:6502

    Topics: Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Base Sequence; Female; Inflammation; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Molecular Sequence Data; Platelet Activating Factor; Shock; Shock, Septic

1994
Altered mitochondrial redox responses in gram negative septic shock in primates.
    Circulatory shock, 1994, Volume: 43, Issue:1

    Topics: Animals; Electron Transport Complex IV; Escherichia coli Infections; Hemoglobins; Male; Microscopy, Electron; Mitochondria; Muscles; Myoglobin; Oxidation-Reduction; Oxygen; Oxygen Consumption; Papio; Platelet Activating Factor; Shock, Septic; Spectrophotometry, Infrared; Tumor Necrosis Factor-alpha

1994
Essential fatty acid-deficient diet modifies PAF levels in stomach and duodenum of endotoxin-treated rats.
    Journal of lipid mediators and cell signalling, 1994, Volume: 9, Issue:2

    Topics: Animals; Duodenum; Escherichia coli; Fatty Acids, Essential; Gastric Mucosa; Lipopolysaccharides; Male; Platelet Activating Factor; Rats; Rats, Inbred Lew; Shock, Septic; Stomach

1994
Systemic and regional hemodynamic changes during endotoxin or platelet activating factor (PAF)-induced shock in rats.
    Circulatory shock, 1993, Volume: 41, Issue:4

    Topics: Animals; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar; Regional Blood Flow; Shock, Septic; Vascular Resistance

1993
Biochemical and pharmacological properties of SR 27388, a dual antioxidant and PAF receptor antagonist.
    Journal of lipid mediators, 1993, Volume: 8, Issue:1

    Topics: Animals; Antioxidants; Azepines; Blood Glucose; Blood Platelets; Cattle; Diabetes Mellitus, Experimental; Free Radical Scavengers; Humans; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Mitochondria, Heart; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Superoxides; Sympathomimetics; Thiazoles; Thiobarbituric Acid Reactive Substances; Triazoles

1993
Effect of the platelet-activating factor antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the haemodynamic changes in canine experimental endotoxic shock.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Animals; Dogs; Endotoxins; Female; Hemodynamics; Ibuprofen; Isoquinolines; Male; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines

1993
Effect of platelet-activating factor on basal and insulin-mediated system A amino acid transport in rat soleus muscle.
    Circulatory shock, 1993, Volume: 40, Issue:1

    Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Disease Models, Animal; Insulin; Inulin; Male; Muscles; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic; Sodium

1993
[Experimental studies on the relation of platelet activating factor (PAF) to high mortality in sublethal endotoxemia after massive hepatectomy and effects of its antagonist].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:5

    Topics: Animals; Disseminated Intravascular Coagulation; Endotoxins; Escherichia coli; Hepatectomy; Liver; Male; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Shock, Septic

1993
An antagonist of platelet-activating factor suppresses endotoxin-induced tumor necrosis factor and mortality in mice pretreated with carrageenan.
    Infection and immunity, 1993, Volume: 61, Issue:2

    Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Isoquinolines; Leukotrienes; Lipopolysaccharides; Male; Mice; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha

1993
Protective effect of diclofenac sodium against endotoxic shock in anaesthetized pigs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:2

    Topics: Animals; Blood Cell Count; Blood Glucose; Diclofenac; Eicosanoids; Female; Hemodynamics; Hemoglobins; Lipopolysaccharides; Platelet Activating Factor; Regional Blood Flow; Shock, Septic; Swine; Tumor Necrosis Factor-alpha

1993
Clinical and experimental studies on the role of platelet-activating factor (PAF) in the pathogenesis of septic DIC.
    Surgery today, 1993, Volume: 23, Issue:3

    Topics: Aged; Animals; Blood Pressure; Disseminated Intravascular Coagulation; Female; Fibrinolysis; Guanidines; Humans; Male; Middle Aged; Neoplasms; Platelet Activating Factor; Platelet Count; Postoperative Complications; Rabbits; Serine Proteinase Inhibitors; Shock, Septic; Thiazoles; Thiazolidines

1993
Effect of platelet activating factor antagonist (TCV-309) on lung injury in dogs with experimentally endotoxin-induced shock.
    The Journal of veterinary medical science, 1995, Volume: 57, Issue:4

    Topics: Animals; Dogs; Escherichia coli; Isoquinolines; Lipopolysaccharides; Lung; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Edema; Pulmonary Surfactants; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines

1995
Inhibition of endotoxin-induced microvascular leakage by a platelet-activating factor antagonist and 5-lipoxygenase inhibitor.
    Shock (Augusta, Ga.), 1995, Volume: 4, Issue:5

    Topics: Analysis of Variance; Animals; Capillary Permeability; Cell Adhesion; Cheek; Cricetinae; Endothelium, Vascular; Furans; Leukocytes; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Methylurea Compounds; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Thiazoles

1995
Platelet-activating factor augments lipopolysaccharide-induced nitric oxide formation by rat Kupffer cells.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:6

    Topics: Animals; Arginine; Biological Transport, Active; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Kinetics; Kupffer Cells; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Shock, Septic

1996
Inhaled nitric oxide prevents experimental platelet activating factor-induced shock.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:8

    Topics: Administration, Inhalation; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Platelet Activating Factor; Random Allocation; Shock, Septic; Swine

1996
Role for intracellular platelet-activating factor in the circulatory failure in a model of gram-positive shock.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Acute Kidney Injury; Animals; Azepines; Cells, Cultured; Diterpenes; Ginkgolides; Hemodynamics; Lactones; Lipopolysaccharides; Lung; Male; Nitric Oxide Synthase; Nitrites; Norepinephrine; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar; Shock, Septic; Streptomyces; Teichoic Acids; Triazoles; Tumor Necrosis Factor-alpha

1995
Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist.
    Shock (Augusta, Ga.), 1996, Volume: 5, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Lipopolysaccharides; Lung; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Stroke Volume; Swine; Thiazoles; Thromboxane B2; Vascular Resistance

1996
Platelet activating factor mediates cardiopulmonary dysfunction during graded bacteremic shock.
    The Journal of trauma, 1996, Volume: 41, Issue:2

    Topics: Aeromonas hydrophila; Animals; Hemodynamics; Platelet Activating Factor; Pulmonary Gas Exchange; Shock, Septic; Swine; Tumor Necrosis Factor-alpha

1996
Nitrite/nitrate (NOX) and type II phospholipase A2, leukotriene B4, and platelet-activating factor levels in patients with septic shock.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 92, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Group II Phospholipases A2; Humans; Leukotriene B4; Middle Aged; Nitrates; Nitrites; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic

1996
Role of platelet-activating factor and prostanoids in hemodynamic changes in rat experimental endotoxic shock.
    Japanese journal of pharmacology, 1996, Volume: 71, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Fatty Acids, Monounsaturated; Hemodynamics; Ibuprofen; Isoquinolines; Male; Platelet Activating Factor; Prostaglandins; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Shock, Septic; Tetrahydroisoquinolines

1996
Role of platelet-activating factor antagonism in posthemorrhage septic shock in pigs.
    The Journal of trauma, 1996, Volume: 41, Issue:4

    Topics: Animals; Body Temperature; Cardiac Output; Heart Rate; Hemodynamics; Leucine; Platelet Activating Factor; Shock, Hemorrhagic; Shock, Septic; Swine; Vascular Resistance

1996
Ethanol suppresses endotoxin but not platelet activating factor-induced hypotension and nitric oxide.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:7

    Topics: Alcohol Drinking; Alcoholic Intoxication; Animals; Blood Pressure; Endotoxemia; Ethanol; Immune Tolerance; Male; Neutrophils; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic; Tumor Necrosis Factor-alpha

1996
Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor.
    The EMBO journal, 1997, Jan-02, Volume: 16, Issue:1

    Topics: Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Endotoxins; Female; Fertility; Guinea Pigs; Male; Melanoma, Experimental; Methacholine Chloride; Mice; Mice, Transgenic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sex Ratio; Shock, Septic; Skin Neoplasms

1997
Role of platelet-activating-factor (PAF) on cellular responses after stimulation with leptospire lipopolysaccharide.
    Microbiology and immunology, 1997, Volume: 41, Issue:3

    Topics: Animals; Cell Adhesion; Cell Aggregation; Endothelium, Vascular; Humans; Leptospira interrogans; Lipopolysaccharides; Platelet Activating Factor; Platelet Aggregation; Rabbits; Shock, Septic

1997
Effects of a new platelet-activating factor antagonist, UR-12670, on several endotoxic shock markers in rats.
    Drugs under experimental and clinical research, 1997, Volume: 23, Issue:5-6

    Topics: Acid Phosphatase; Animals; Blood Glucose; Capillary Permeability; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Imidazoles; L-Lactate Dehydrogenase; Lactic Acid; Lipopolysaccharides; Male; Partial Thromboplastin Time; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prothrombin Time; Pyridines; Rats; Rats, Sprague-Dawley; Shock, Septic

1997
[The role of platelet activating factor in regulation of the phagocytic function of macrophages from different organs].
    Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:3

    Topics: Animals; Biological Factors; Lipopolysaccharides; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Phagocytosis; Platelet Activating Factor; Pseudomonas aeruginosa; Shock, Septic; Spleen

1998
The platelet-activating factor antagonist BB-882 does not improve tissue oxygen extraction in endotoxic shock.
    Journal of critical care, 1998, Volume: 13, Issue:2

    Topics: Animals; Cardiac Output; Cardiac Tamponade; Dogs; Endotoxins; Escherichia coli; Female; Hemodynamics; Leucine; Male; Myocardial Contraction; Oxygen; Oxygen Consumption; Platelet Activating Factor; Pulmonary Wedge Pressure; Shock, Septic

1998
Echocardiographic and survival studies in mice undergoing endotoxic shock: effects of genetic ablation of inducible nitric oxide synthase and pharmacologic antagonism of platelet-activating factor.
    The Journal of surgical research, 1999, Volume: 86, Issue:2

    Topics: Animals; Echocardiography; Lipopolysaccharides; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pharmaceutical Vehicles; Platelet Activating Factor; Propionibacterium acnes; Shock, Septic; Survival Analysis

1999
Platelet-activating factor and arachidonic acid metabolites mediate tumor necrosis factor and eicosanoid kinetics and cardiopulmonary dysfunction during bacteremic shock.
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Aeromonas hydrophila; Animals; Arachidonic Acid; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Eicosanoids; Female; Gram-Negative Bacterial Infections; Heart Diseases; Hemodynamics; Hypertension, Pulmonary; Lipoxygenase Inhibitors; Masoprocol; Oxazoles; Oxygen; Oxygen Consumption; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Swine; Thromboxane A2; Triazoles; Tumor Necrosis Factor-alpha

1999
Platelet-activating factor (PAF)-induced decreases in whole-body and skeletal muscle protein synthesis.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:4

    Topics: Amino Acids; Animals; Carbohydrate Metabolism; Kinetics; Leucine; Liver; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Platelet Activating Factor; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA; Shock, Septic

2000
Role of eicosanoids in regulation of macrophage phagocytic functions by platelet-activating factor during endotoxic shock.
    Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:9

    Topics: Animals; Eicosanoids; Macrophages; Male; Mice; Mice, Inbred C57BL; Phagocytosis; Platelet Activating Factor; Shock, Septic

2000
Role of gut flora on intestinal group II phospholipase A2 activity and intestinal injury in shock.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Bacterial Physiological Phenomena; Blood Pressure; Germ-Free Life; Group II Phospholipases A2; Hematocrit; Intestine, Small; Leukocyte Count; Lipopolysaccharides; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic

2001
Hemofiltration reduces the serum priming activity on neutrophil chemiluminescence in septic patients.
    Kidney international, 2001, Volume: 60, Issue:4

    Topics: Acute Kidney Injury; Aged; Blood Physiological Phenomena; Hemofiltration; Humans; Interleukin-8; Luminescent Measurements; Middle Aged; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Reference Values; Respiratory Burst; Shock, Septic; Uremia

2001
Role of PAF and cytokines in microvascular tissue injury.
    The Journal of laboratory and clinical medicine, 1992, Volume: 119, Issue:5

    Topics: Cell Adhesion; Cell Movement; Cytokines; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Interleukin-1; Interleukin-2; Lactones; Microcirculation; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Tumor Necrosis Factor-alpha

1992
More on pathogenesis and treatment of septic shock.
    European journal of epidemiology, 1992, Volume: 8, Issue:5

    Topics: Amino Acid Oxidoreductases; Gram-Negative Bacteria; Humans; Immunologic Factors; Nitric Oxide Synthase; Platelet Activating Factor; Shock, Septic

1992
Effect of platelet-activating factor antagonist and leukotriene antagonist on endotoxin shock in the rat: role of the leukocyte.
    Circulatory shock, 1992, Volume: 38, Issue:1

    Topics: Animals; Chromones; Leukocyte Count; Leukocytes; Leukotriene Antagonists; Male; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; Shock, Septic; Vinblastine

1992
Endotoxin-induced lung vascular injury: role of platelet activating factor, tumor necrosis factor and neutrophils.
    Clinical research, 1992, Volume: 40, Issue:3

    Topics: Animals; Endotoxins; Humans; Lung; Neutrophils; Platelet Activating Factor; Rats; Respiratory Distress Syndrome; Shock, Septic; Tumor Necrosis Factor-alpha

1992
PF-5901 inhibits gastrointestinal platelet-activating factor synthesis in vivo.
    European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Intestinal Mucosa; Jejunum; Male; Nematode Infections; Nippostrongylus; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic

1992
Pharmacological profile of G619, a new platelet aggregation inhibitor.
    Thrombosis research, 1992, May-15, Volume: 66, Issue:4

    Topics: Adenosine Diphosphate; Animals; Benzamides; Calcium; Collagen; Dogs; Epinephrine; Fibrinogen; Humans; Male; Phenylacetates; Picolines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Thrombin; Thromboxane B2; Vasoconstriction

1992
Lethal and non-lethal course of endotoxic shock is determined by interactions between tumor necrosis factor, platelet activating factor and eicosanoids.
    Pathologie-biologie, 1992, Volume: 40, Issue:8

    Topics: Animals; Blood Pressure; Diterpenes; Eicosanoids; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Lactones; Platelet Activating Factor; Shock, Septic; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha

1992
Time course of various inflammatory mediators during recurrent endotoxemia.
    Biochemical pharmacology, 1992, May-28, Volume: 43, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Inflammation; Interleukin-6; Lipopolysaccharides; Platelet Activating Factor; Pulmonary Wedge Pressure; Shock, Septic; Swine; Thromboxane B2; Time Factors; Tumor Necrosis Factor-alpha

1992
Beneficial effects of TCV-309, a novel potent and selective platelet activating factor antagonist in endotoxin and anaphylactic shock in rodents.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Furans; Hemolysis; Humans; Hypotension; Isoquinolines; Male; Microsomes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Shock, Septic; Tetrahydroisoquinolines; Triazoles

1992
Platelet activating factor is one of the mediators involved in endotoxic shock in pigs.
    Journal of lipid mediators, 1991, Volume: 4, Issue:3

    Topics: Animals; Diterpenes; Escherichia coli; Female; Ginkgolides; Hemodynamics; Hemoglobins; Lactones; Leukocyte Count; Lipopolysaccharides; Platelet Activating Factor; Platelet Count; Regional Blood Flow; Shock, Septic; Swine; Tumor Necrosis Factor-alpha

1991
Sequential release of tumour necrosis factor, platelet activating factor and eicosanoids during endotoxin shock in anaesthetized pigs: protective effects of indomethacin.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: Anesthesia; Animals; Blood Chemical Analysis; Blood Glucose; Eicosanoids; Escherichia coli; Female; Hemodynamics; Indomethacin; Lipopolysaccharides; Platelet Activating Factor; Regional Blood Flow; Shock, Septic; Swine; Tumor Necrosis Factor-alpha

1991
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
    European journal of pharmacology, 1991, Dec-03, Volume: 205, Issue:3

    Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles

1991
Myoelectric intestinal disturbances in Escherichia coli endotoxic shock in rats. Involvement of platelet-activating factor.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Diterpenes; Duodenum; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Jejunum; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic

1991
Platelet-activating factor induces intestinal necrosis, but not septic shock, in germ-free and specific-pathogen-free rodents.
    Burns : journal of the International Society for Burn Injuries, 1991, Volume: 17, Issue:4

    Topics: Animals; Female; Germ-Free Life; Intestine, Small; Lipopolysaccharides; Mice; Mice, Inbred C3H; Necrosis; Platelet Activating Factor; Rats; Salmonella typhi; Shock, Septic; Specific Pathogen-Free Organisms

1991
The interrelation between TNF, IL-6, and PAF secretion induced by LPS in an in vivo and in vitro murine model.
    Lymphokine and cytokine research, 1991, Volume: 10, Issue:1-2

    Topics: Animals; Biological Assay; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Interleukin-6; Lipopolysaccharides; Mice; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1991
Effects of platelet-activating factor antagonist SRI 63-441 on endotoxin-induced changes in rat mesenteric microcirculation.
    Yao xue xue bao = Acta pharmaceutica Sinica, 1991, Volume: 26, Issue:1

    Topics: Animals; Endotoxins; Escherichia coli; Female; Male; Microcirculation; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Inbred Strains; Shock, Septic; Splanchnic Circulation

1991
A triazolodiazepine platelet activating factor receptor antagonist (WEB 2086) reduces pulmonary dysfunction during endotoxin shock in swine.
    The Journal of trauma, 1991, Volume: 31, Issue:7

    Topics: Animals; Azepines; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Endotoxins; Leukocyte Count; Lung; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Pulmonary Gas Exchange; Salmonella; Shock, Septic; Swine; Swine, Miniature; Tissue Plasminogen Activator; Triazoles; Vascular Resistance

1991
Mechanism of acute gastrointestinal mucosal damage in endotoxic shock and the effect of Fragmin.
    Seminars in thrombosis and hemostasis, 1990, Volume: 16 Suppl

    Topics: Acute Disease; Animals; Benzoquinones; Dogs; Gastric Mucosa; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Intestinal Mucosa; Leukotriene B4; Lipoxygenase Inhibitors; Necrosis; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic

1990
[PAF and diseases].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1991, Volume: 36, Issue:3

    Topics: Animals; Female; Humans; Inflammation; Ischemia; Nephritis; Platelet Activating Factor; Pregnancy; Shock, Septic; Stomach Ulcer

1991
Relationships between tumour necrosis factor, eicosanoids and platelet-activating factor as mediators of endotoxin-induced shock in mice.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Capillary Permeability; Diterpenes; Drug Interactions; Eicosanoids; Endotoxins; Escherichia coli; Female; Ginkgolides; Hematocrit; Indomethacin; Lactones; Mice; Platelet Activating Factor; Recombinant Proteins; Shock, Septic; Tumor Necrosis Factor-alpha

1990
Tumor necrosis factor (TNF) and endotoxin prime effects of PAF in vivo.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Azepines; Drug Interactions; Endotoxins; Gastrointestinal Transit; Mice; Platelet Activating Factor; Shock, Septic; Triazoles; Tumor Necrosis Factor-alpha

1990
Effect of the PAF antagonist BN 52021 in ovine endotoxin shock.
    Journal of lipid mediators, 1990, Volume: 2 Suppl

    Topics: Animals; Diterpenes; Ginkgolides; Lactones; Lipopolysaccharides; Lung; Lymph; Platelet Activating Factor; Pulmonary Circulation; Sheep; Shock, Septic; Water-Electrolyte Balance

1990
Platelet activating factor receptor antagonist improves survival and attenuates eicosanoid release in severe endotoxemia.
    Annals of surgery, 1990, Volume: 211, Issue:3

    Topics: Animals; Dinoprostone; Diterpenes; Endotoxins; Escherichia coli; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2

1990
Platelet activating factor (PAF) and tumor necrosis factor-alpha (TNF alpha) interactions in endotoxemic shock: studies with BN 50739, a novel PAF antagonist.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1

    Topics: Animals; Azepines; Blood Cells; Hemodynamics; Humans; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Recombinant Proteins; Shock, Septic; Thromboxanes; Triazoles; Tumor Necrosis Factor-alpha

1990
Platelet-activating factor or a platelet-activating factor antagonist decreases tumor necrosis factor-alpha in the plasma of mice treated with endotoxin.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:5

    Topics: Alprazolam; Animals; Cell Line; Endotoxins; Enzyme-Linked Immunosorbent Assay; Indomethacin; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Platelet Activating Factor; RNA, Messenger; Shock, Septic; Tumor Necrosis Factor-alpha

1990
Contribution of platelet activating factor to hemodynamic and sympathetic responses to bacterial endotoxin in conscious rats.
    Circulatory shock, 1990, Volume: 32, Issue:2

    Topics: Animals; Azepines; Blood Glucose; Blood Pressure; Catecholamines; Endotoxins; Heart Rate; Hemodynamics; Lactates; Lactic Acid; Male; Platelet Activating Factor; Rats; Shock, Septic; Sympathetic Nervous System; Triazoles

1990
Effects of in vivo 'priming' on endotoxin-induced hypotension and tissue injury. The role of PAF and tumor necrosis factor.
    The American journal of pathology, 1990, Volume: 136, Issue:4

    Topics: Animals; BCG Vaccine; Endotoxins; Gastrointestinal Diseases; Hypotension; Lipopolysaccharides; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Inbred Strains; Shock, Septic; Tumor Necrosis Factor-alpha; Zymosan

1990
Relationship between PAF-acether and thromboxane A2 biosynthesis in endotoxin-induced intestinal damage in the rat.
    Prostaglandins, 1989, Volume: 38, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Escherichia coli; Ethanol; Imidazoles; Indomethacin; Jejunum; Lipopolysaccharides; Male; Methacrylates; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane A2; Thromboxane-A Synthase

1989
Endotoxin shock, kinin system and PAF-acether in the rat.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Animals; Blood Pressure; Diterpenes; Exudates and Transudates; Ginkgolides; Hematocrit; Lactones; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred BN; Rats, Inbred Strains; Shock, Septic; Species Specificity

1989
[Effect of an extract from the cauline of Piper kadsura ohwi on endotoxin-induced hypotension and lung injury in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1989, Volume: 14, Issue:11

    Topics: Animals; Blood Pressure; Capillary Permeability; Drugs, Chinese Herbal; Female; Hypotension; Platelet Activating Factor; Pulmonary Edema; Rats; Rats, Inbred Strains; Shock, Septic

1989
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles

1989
Beneficial effects of prostaglandin E2 in endotoxic shock are unrelated to effects on PAF-acether synthesis.
    Prostaglandins, 1989, Volume: 37, Issue:2

    Topics: Animals; Capillary Permeability; Dinoprostone; Duodenum; Gastric Mucosa; Lung; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach

1989
The involvement of platelet-activating factor (PAF)-induced monocyte activation and tumor necrosis factor (TNF) production in shock.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Cytotoxicity, Immunologic; Diterpenes; Ginkgolides; Humans; Kinetics; Lactones; Monocytes; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha

1989
Effect of PAF-antagonists in endotoxin shock--ovine and rat experiments.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Azepines; Blood Pressure; Diterpenes; Ginkgolides; Hemodynamics; Kinetics; Lactones; Lymph; Male; Platelet Activating Factor; Proteins; Pulmonary Artery; Rats; Rats, Inbred Strains; Sheep; Shock, Septic; Triazines; Triazoles

1989
Influence of inhibitors of the eicosanoid metabolism, and of eicosanoids- and PAF-acether antagonists on mortality and some biochemical parameters of three shock models.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Anaphylaxis; Animals; Aspirin; Diterpenes; Fatty Acids, Unsaturated; Female; Ginkgolides; Imidazoles; Ketotifen; Lactones; Masoprocol; Mice; Naphthalenes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Shock, Septic

1989
Beneficial effects of (RS)-2-methoxy-3-(octadecylcarbamoyloxy)propyl 2-(3-thiazolio)ethyl phosphate, a specific PAF antagonist, in endotoxin and anaphylactic shock.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 15

    Topics: Anaphylaxis; Animals; Blood Platelets; Hypotension; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Thiazoles

1985
Influence of inhibitors of the eicosanoid metabolism, of antagonists of the eicosanoids and of PAF on mortality assayed in three biochemically characterized shock models.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Anaphylaxis; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Lipoxygenase Inhibitors; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic

1988
[Interactions between platelet activating factor and leukotrienes during endotoxin shock in the rat].
    Masui. The Japanese journal of anesthesiology, 1988, Volume: 37, Issue:12

    Topics: Animals; Leukotrienes; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic

1988
Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.
    Gastroenterology, 1987, Volume: 93, Issue:4

    Topics: Animals; Blood Pressure; Disease Models, Animal; Diterpenes; Escherichia coli Infections; Ethanol; Ginkgolides; Glyceryl Ethers; Intestine, Small; Lactones; Lipopolysaccharides; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach; Thiazoles

1987
Gastrointestinal plasma leakage in endotoxic shock. Inhibition by prostaglandin E2 and by a platelet-activating factor antagonist.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:7

    Topics: Animals; Blood Pressure; Blood Proteins; Digestive System; Dinoprostone; Male; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Shock, Septic; Thiazoles

1987
In vivo inhibition of plasma protein leakage and Salmonella enteritidis-induced mortality in the rat by a specific paf-acether antagonist: BN 52021.
    Agents and actions, 1986, Volume: 17, Issue:3-4

    Topics: Animals; Blood Proteins; Capillary Permeability; Diterpenes; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella enteritidis; Salmonella Infections, Animal; Shock, Septic

1986
Interference of the PAF-acether antagonist BN 52021 with endotoxin-induced hypotension in the guinea-pig.
    Prostaglandins, 1986, Volume: 32, Issue:6

    Topics: Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Hypotension; Lactones; Male; Plant Extracts; Platelet Activating Factor; Shock, Septic; Thrombocytopenia

1986
Protective effect of WEB 2086, a novel antagonist of platelet activating factor, in endotoxin shock.
    European journal of pharmacology, 1987, Mar-17, Volume: 135, Issue:2

    Topics: Animals; Azepines; Blood Pressure; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Triazines; Triazoles

1987
Inhibition of rat endotoxin-induced lethality by BN 52021 and BN 52063, compounds with PAF-acether antagonistic effect and protease-inhibitory activity.
    International journal of tissue reactions, 1987, Volume: 9, Issue:1

    Topics: Animals; Diterpenes; Endotoxins; Ginkgolides; Lactones; Male; Phospholipases A; Plant Extracts; Platelet Activating Factor; Protease Inhibitors; Rats; Rats, Inbred Strains; Shock, Septic; Trypsin

1987
Effects of ONO-6240, a platelet-activating factor antagonist, on endotoxin shock in unanesthetized sheep.
    Prostaglandins, 1986, Volume: 31, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Endotoxins; Hemodynamics; Leukocyte Count; Lung; Lymph; Oxygen; Platelet Activating Factor; Platelet Count; Sheep; Shock, Septic; Thiazoles; Vascular Resistance

1986
PAF-acether and leukotriene participation in acute circulatory shock.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Dogs; Guinea Pigs; Hemodynamics; Male; Mice; Microcirculation; Platelet Activating Factor; Regional Blood Flow; Shock; Shock, Hemorrhagic; Shock, Septic; SRS-A

1986
Interference of BN 52021, a PAF-acether antagonist, with endotoxin-induced hypotension in the guinea-pig.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Animals; Blood Platelets; Blood Pressure; Diterpenes; Endotoxins; Ginkgolides; Guinea Pigs; Hypotension; Lactones; Plant Extracts; Platelet Activating Factor; Shock, Septic

1986
The relative role of PAF-acether and icosanoids in septic shock.
    Pharmacological research communications, 1986, Volume: 18 Suppl

    Topics: Animals; Anti-Inflammatory Agents; Diterpenes; Eicosanoic Acids; Ginkgolides; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic

1986
Effects of a platelet-activating factor antagonist, CV-3988, on different shock models in the rat.
    Circulatory shock, 1986, Volume: 20, Issue:3

    Topics: Animals; Blood Pressure; Decerebrate State; Male; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Shock, Hemorrhagic; Shock, Septic; Thiazoles

1986
Is platelet activating factor (PAF) a mediator of endotoxin shock?
    European journal of pharmacology, 1985, Feb-26, Volume: 109, Issue:2

    Topics: Animals; Blood Pressure; Endotoxins; Male; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Thiazoles

1985