1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Disease Models, Animal in 269 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 31 (11.52) | 18.7374 |
1990's | 119 (44.24) | 18.2507 |
2000's | 72 (26.77) | 29.6817 |
2010's | 44 (16.36) | 24.3611 |
2020's | 3 (1.12) | 2.80 |
Authors | Studies |
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Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Arifulin, EA; Azbukina, NV; Baksheeva, VE; Chistyakov, DV; Chistyakov, VV; Gancharova, OS; Goriainov, SV; Komarov, SV; Philippov, PP; Senin, II; Sergeeva, MG; Tikhomirova, NK; Tiulina, VV; Zamyatnin, AA; Zernii, EY | 1 |
Awoyemi, AA; Bihl, JC; Chen, J; Chen, Y; Cool, DR; Fahy, KE; Johnson, RM; Kelly, LE; Liu, L; Rapp, CM; Thapa, P; Travers, JB | 1 |
Hasegawa, A; Ogawa, M; Ohmori, K; Ohno, H; Osada, H; Sasaki, K; Shimoda, M; Shirai, J; Watanabe, M; Yanuma, N | 1 |
Dong, Z; Li, C; Liu, H; Liu, Y; Ren, J | 1 |
Hao, TT; Huang, TT; Li, JM; Lin, CR; Liu, JX; Ren, JG; Ren, JX; Shi, YH; Wang, M | 1 |
Anthony, DC; Barteneva, NS; Dukhinova, M; Kopeikina, E; Kuznetsova, I; Levchuk, K; Liu, JYH; Ponomarev, ED; Rudd, J; Strekalova, T; Veniaminova, E; Veremeyko, T; Wing-Ho, KK; Yau, SSY; Yung, AWY; Yung, WH | 1 |
Babu, ST; Hooper, LV; Mirpuri, J; Niu, X; Raetz, M; Savani, RC | 1 |
Cao, L; Chen, S; Ma, CG; Tang, J; Wang, Q; Xiao, BG; Xiao, W; Yu, WB | 1 |
Chen, K; Xia, SH; Xiang, XH; Xu, W | 1 |
Asano, M; Cui, H; Du, W; Okamoto, Y; Shibamoto, T; Takuwa, N; Takuwa, Y; Yoshioka, K; Zhang, W | 1 |
Bessi, VL; Bitencourt, CS; Borgeat, P; Faccioli, LH; Hamdan, L; Huynh, DN; Lefebvre, JS; Lévesque, T; Marleau, S; Ménard, L; Sohouhenou, F | 1 |
Cho, KD; Im, SY; Jang, KY; Kim, HA; Kim, HK; Kim, KJ; Lee, HK | 1 |
Claßen, A; Danker, K; Forkel, S; Hildmann, A; John, SM; Schön, M; Schön, MP | 1 |
Berbée, JF; Habets, KL; Havekes, LM; Kooijman, S; Korporaal, SJ; Lammers, B; Meurs, I; Rensen, PC; Romijn, JA; van der Stoep, M; van Eck, M | 1 |
Abdulnour, RE; Colas, RA; Colby, JK; Dalli, J; Krishnamoorthy, N; Levy, BD; Petasis, NA; Serhan, CN; Tan, SH; Timmons, JY | 1 |
Ebina, K; Oe, K; Sato, A; Yamanaka, H; Yokoyama, I | 1 |
Albrecht, M; Dombrowsky, H; Frerichs, I; Goldmann, T; Lautenschläger, I; Sarau, J; Uhlig, S; Weiler, N; Zitta, K | 1 |
Deng, L; Geng, Y; Li, T; Lü, J; Ma, Y; Sun, F; Wang, C | 1 |
Huang, HM; Huang, JF; Wang, ZJ; Yang, YF; Yao, Y; Zhao, HP | 1 |
Dohi, T; Kitayama, T; Morita, K; Motoyama, N; Shiraishi, S | 1 |
Chatziralli, IP; Demopoulos, CA; Moschos, MM; Papakonstantinou, VD; Stamatakis, G; Tsatsos, M | 1 |
Ahmed, S; Dima, L; Gul, S; Moga, M; Ze Jaafar, H; Zia-Ul-Haq, M | 1 |
Bai, XD; Guo, SJ; Hu, S; Hu, XH; Li, ZY; Liu, R; Wang, SM; Zhou, FQ | 1 |
Andolina, G; Calado, Â; Faggio, C; Saldanha, C; Silva-Herdade, AS | 1 |
Bazan, NG; Belayev, L; Bhattacharjee, S; Fang, Z; Gordon, WC; Musto, AE; Raulji, CM; Rosencrans, RF; Walker, CP | 1 |
Bae, YS; Im, SY; Kim, HK; Lee, HK; Song, CH | 1 |
Behnk, A; Günther, A; Hecker, M; Mayer, K; Ott, J; Pose, A; Schaefer, MB; Schulz, R; Seeger, W; Weissmann, N | 1 |
Bloechle, C; Izbicki, JR; Kaifi, J; Kluth, D; Mann, O; Schneider, C; Strate, T; Tiefenbacher, WJ; Yekebas, E | 1 |
Farhan, S; Glogar, D; Gyöngyösi, M; Hemetsberger, H; Hemetsberger, R; Huber, K; Pavo, I; Petrasi, Z; Posa, A; Sperker, W; Strehblow, C | 1 |
Baskind, H; De Plaen, IG; Hsueh, W; Liu, SX; Tian, R | 1 |
Mahuran, D; Rigat, B; Shehnaz, D; Yeger, H | 1 |
Clayette, P; Dash, PK; Dong, CZ; Dou, H; Eggert, D; Gelbard, HA; Gendelman, HE; Gorantla, S; Heymans, F; Poluektova, L; Serradji, N | 1 |
Guo, H; Li, B; Liu, LP; Shi, B; Yin, C | 1 |
Cheng, L; Han, X; Shi, Y | 1 |
Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T | 1 |
Hasegawa, S; Inoue, K; Ishii, S; Kohro, Y; Shimizu, T; Shiratori, M; Tsuda, M | 1 |
Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J | 1 |
Karasuyama, H; Mukai, K; Obata, K; Tsujimura, Y | 1 |
Dermon, C; Panagis, L; Prokosch, V; Thanos, S; Volk, GF | 1 |
Cassali, GD; Fagundes, CT; Garcia, CC; Guabiraba, R; Machado, AV; Polidoro, RB; Russo, RC; Salgado, AP; Sousa, LP; Tavares, LP; Teixeira, MM | 1 |
Chen, R; Febbraio, M; Liu, J; Marathe, GK; McIntyre, TM; Zou, W | 1 |
Musto, AE; Samii, M | 1 |
Arribas, B; Bailón, E; Balsa, D; Camuesco, D; Comalada, M; Cueto-Sola, M; Gálvez, J; Garrido-Mesa, N; Janer, G; Merlos, M; Rodríguez-Cabezas, ME; Román, J; Xaus, J; Zarzuelo, A | 1 |
de Lima, CD; de Oliveira, AV; Machado, GB; Plotkowski, MC; Saliba, AM; Suassuna, JH | 1 |
Büchler, MW; Gebhard, MM; Hackert, T; Hartwig, W; Kaiser, H; Klar, E; Schmidt, J; Werner, J | 1 |
Aoki, J; Ebina, K; Kumagai, T; Sato, A | 1 |
Gao, CR; Guo, XJ; Yan, XB; Yang, K | 1 |
Bazan, HE; He, J; Kakazu, A; Kenchegowda, S | 1 |
Gorman, S; Hart, PH | 1 |
Herndon, B; Molteni, A; Nzabi, M; Quinn, T; Wasson, N | 1 |
Pawlowic, MC; Zhang, K | 1 |
Uomo, G | 1 |
Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
Dohi, T; Kanematsu, T; Kitayama, T; Morita, K; Motoyama, N; Nishimura, F; Shiraishi, S; Uezono, Y | 1 |
Barcelos, L; Klein, A; Machado, FS; Santana, GC; Silva, JS; Talvani, A; Teixeira, MM | 1 |
Ewer, AK | 1 |
Göggel, R; Hoffman, S; Narumiya, S; Nüsing, R; Uhlig, S | 1 |
Michibayashi, T | 1 |
Kawasaki, T; Kobayashi, Y; Murohisa, G; Nakamura, H; Nakamura, S | 1 |
Abe, Y; Hori, T; Kasuya, H; Suzuki, S; Yamanishi, Y | 1 |
Kulikov, VI; Muzya, GI | 1 |
Hirayama, K; Kashiwabara, H; Nakamura, S; Nakamura, T; Sakaguchi, T; Sunayama, K; Yokoi, Y | 1 |
Mahgoub, AA | 1 |
Ishii, S; Pinho, V; Shimizu, T; Soares, AC; Souza, DG; Teixeira, MM | 1 |
Abu-Zidan, FM | 1 |
Huseyinov, A; Ozutemiz, O; Saruc, M; Turkel, N; Tuzcuoglu, I; Yuce, G; Yuceyar, H | 1 |
Calabró, P; Chiariello, M; Cirillo, P; Corcione, N; D'Andrea, D; De Felice, M; Gargiulo, A; Golino, P; Piro, O; Ragni, M; Ravera, M; Rosica, A; Tommasini, P; Vigorito, F | 1 |
Kato, M; Kurose, T; Miyaji, S; Oda, T | 1 |
Amemiya, T; Fujimura, M; Ishiura, Y; Kurashima, K; Myou, S; Nobata, K; Nonomura, A | 1 |
Akisu, M; Baka, M; Huseyinov, A; Kultursay, N | 1 |
Chien, EK; Elovitz, MA; Phillippe, M; Rychlik, DF; Wang, Z | 1 |
Kraft, M; Lerch, MM; Mayerle, J; Meister, T; Simon, P | 1 |
Alloatti, G; Hirsch, E; Lembo, G; Montrucchio, G | 1 |
Slomiany, A; Slomiany, BL | 1 |
Ishii, S; Nagase, T; Ouchi, Y; Shimizu, T; Shindou, H; Takizawa, H | 1 |
Jancar, S; Ribeiro-Dias, F; Shio, MT; Timenetsky, J | 1 |
Fukushima, A; Hangstefer, E; Zinchuk, O | 1 |
Backer, CL; Crawford, SE; Huang, L; Huang, X; Mavroudis, C; Mu, Y; Pahl, E; Stellmach, V; Volpert, OV | 1 |
Fukata, K; Fukushima, A; Ueno, H; Zinchuk, O; Zinchuk, V | 1 |
Abo, M; Fujimura, M; Ishiura, Y; Myou, S; Nobata, K; Nonomura, A; Oribe, Y | 1 |
Atilla, G; Baylas, H; Berdeli, AH; Buduneli, E; Buduneli, N; Vardar, S | 1 |
Göggel, R; Uhlig, S | 1 |
Ahn, SK; Jeon, SY; Kim, BG; Kim, EA; Kim, JP | 1 |
Chatterjee, BE; Flower, RJ; Nourshargh, S; Perretti, M; Rosignoli, G; Yona, S; Young, RE | 1 |
Choi, IW; Im, SY; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, JH; Lee, YC; Park, YM; You, HJ | 1 |
Amendoeira, FC; Bandeira-Melo, C; Bozza, PT; Castro-Faria-Neto, HC; Chedier, LM; Figueiredo, MR; Frutuoso, VS; Gomes, GS; Kaplan, MA; Vieira-de-Abreu, A; Weller, PF; Zanon, C | 1 |
Granger, J; Remick, D | 1 |
Chen, HZ; Dong, CZ; Gao, XL; Heymans, F; Huang, H; Li, J; Massicot, F; Miezan Ezoulin, JM | 1 |
Antonopoulou, S; Demopoulos, CA; Iliopoulos, DG; Karantonis, HC; Kavantzas, N; Perrea, DN; Sokolis, DP; Theocharis, SE | 1 |
Amâncio, RT; Bastos, MS; Bozza, FA; Bozza, PT; Castro-Faria-Neto, HC; Gomes, RN; Gouvêa, JM; Japiassú, AM; Larangeira, AP; Prescott, SM; Stafforini, DM; Vianna, RC; Zimmerman, GA | 1 |
Karabina, SA; Ninio, E | 1 |
Choi, IH; Choi, IW; Chung, WC; Kang, NI; Kim, YS; Lee, HK; Song, CH; Woo, HY | 1 |
Aladağ, M; Ara, C; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioğlu, F; Karadağ, N; Karincaoğlu, M; Temel, I; Yücel, N | 1 |
Farooqui, AA; Ong, WY; Vahidy, WH; Yeo, JF | 1 |
Crespo, A; Livia, F; Novoa, E; Pezzulo, A; Sánchez-de León, R; Sznajder, JI; Trejo, H; Urich, D | 1 |
Liu, XT; Pan, XL; Wang, LJ; Wang, S; Zhang, X | 1 |
Atici, A; Bozlu, G; Nayci, A; Okuyaz, C; Polat, A; Taskinlar, H; Turhan, AH | 1 |
Gutbier, B; Ishii, S; Mayer, K; Mitchell, TJ; Owen, JS; Rosseau, S; Schmeck, B; Schütte, H; Suttorp, N; Thomas, MJ; Witzenrath, M | 1 |
Song, CM; Wang, H; Wu, B | 1 |
Andreadou, I; Arkadopoulos, N; Avgerinos, E; Costopanagiotou, C; Diamantopoulou, K; Kostopanagiotou, G; Lekka, M; Nakos, G; Smyrniotis, V | 1 |
Chen, Y; Feng, YY; Lu, YY; Su, SH; Wang, CP; Yang, YP; Zhou, L | 1 |
Chin, TK; Hofmann, PA; Leary, PJ; Morrison, RR; Rajasekaran, S; Tuomanen, EI | 1 |
Chemtob, S; Dorfman, AL; Hardy, P; Joly, S; Lachapelle, P | 1 |
Willoughby, JB; Willoughby, WF | 1 |
Gonzalez-Crussi, F; Hsueh, W | 2 |
Alonso, F; Barat, A; Egido, J; Sánchez-Crespo, M | 1 |
Altavilla, D; Bussolino, F; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Sardella, A; Squadrito, F; Urna, G | 1 |
Martin, JG | 1 |
Antunes, E; Cirino, G; de Nucci, G; Donato, JL; Faro, R; Hyslop, S; Landucci, EC; Marangoni, S; Oliveira, B | 1 |
Chyczewski, L; Dabrowski, A; Gabryelewicz, A | 1 |
Inoue, H; Koshihara, Y; Nagata, N | 1 |
Hughes, SC; Whelan, CJ; Wren, GP | 1 |
Adams, JL; Badger, A; Bolognese, B; Chabot-Fletcher, M; Flamberg, PL; Hall, RH; Marshall, LA; Roshak, A; Sung, CM; Winkler, JD | 1 |
Arima, M; Makino, S; Yukawa, T | 1 |
Langer, JC; Liebman, SM; Monk, PK; Pelletier, GJ | 1 |
Akagi, M; Akagi, R; Fukuishi, N; Kanoh, R; Tachibana, M | 1 |
Lopez-Belmonte, J; Whittle, BJ | 1 |
Denizot, Y; Nathan, N | 1 |
Iikura, Y; Iwama, T; Mori, H; Nagai, H; Nishida, H; Takatsu, K | 1 |
Brunet, F; Dhainaut, JF; Mira, JP | 1 |
Crissinger, KD | 1 |
Fujiwara, S; Kawamura, M; Kitayoshi, T; Nishikawa, K; Takatani, M; Terashita, Z | 1 |
Braquet, PG; Hosford, D; Koltai, M | 1 |
Dosen, P; Gerkens, JF; Smith, AJ | 1 |
Durán, WN; Hobson, RW; Yasuhara, H | 1 |
Feuerstein, G; Neville, LF; Rabinovici, R | 1 |
Scheld, WM; Townsend, GC | 1 |
Caplan, MS; Gonzalez-Crussi, F; Hsueh, W; MacKendrick, W; Sun, X; Tan, X | 1 |
Bernard, GR; Christman, BW | 1 |
Mariscalco, MM | 1 |
Suzuki, S; Toledo-Pereyra, LH | 1 |
Hack, CE; Imai, Y; Kuipers, B; Levi, M; ten Cate, H; ten Cate, JW; van der Poll, T; van Deventer, SJ | 1 |
Caplan, M; Hsueh, W; MacKendrick, W | 1 |
Furukawa, M; Johnston, JM; Lee, EL | 1 |
Anglin, C; Carson, R; Clapp, N; Fretland, D; Hansard, R; Henke, M; Walsh, R; Widomski, D | 1 |
DeJoy, SQ; Jeyaseelan, R; Kerwar, SS; Oronsky, AL; Pickett, WC; Torley, LW; Wick, MM; Wissner, A | 1 |
Chen, BN; McLennan, PL; Menadue, MF; Oliver, JR; Rayner, TE | 1 |
Aosaki, N; Minezaki, K; Nakamura, H; Nakazawa, H; Ohsuzu, F; Senoh, M; Tuji, C | 1 |
Boruff, JS; Karlstad, MD | 1 |
Imura, Y; Kawamura, M; Nishikawa, K; Shino, A; Terashita, Z | 1 |
Christopherson, TJ; Hofer, RE; Lanier, WL; Milde, JH; Scheithauer, BW | 1 |
Alsina, J; Bordalba, JR; Carrera, M; Griño, JM; Martinez-Castelao, A; Moliner, R; Seron, D; Torras, J; Valles, J | 1 |
Becker, K; Förster, W; Grupe, R; Lueddeckens, G | 1 |
Abraham, WM | 2 |
Donigi-Gale, D; Granger, DN; McKnight, GW; Shoupe, TS; Wallace, JL | 1 |
Boichot, E; Braquet, P; Lagente, V; Mencia-Huerta, JM | 1 |
Cormier, Y; Israel-Assayag, E; Sirois, P; Tremblay, GM | 1 |
Endo, S; Hirashima, Y; Karasawa, K; Nojima, S; Otsuji, T; Takaku, A | 1 |
Pretolani, M; Vargaftig, BB | 1 |
Seow, WK; Thong, YH; Wong, CW | 1 |
Misawa, M; Sugiyama, Y | 1 |
Bugelski, PJ; Esser, KM; Feuerstein, G; Hillegass, LM; Rabinovici, R; Vernick, J | 1 |
Basile, AS; Kustova, Y; Markey, SP; Morse, HC; Nishida, K; Sei, Y; Skolnick, P | 1 |
Markey, SP; Nishida, K | 1 |
Aguirre, B; Alvarez, T; Fernandez, L; González-Fajardo, JA; Ramos, G; Vaquero, C | 1 |
Goldsmith, JA; Kavanagh, BP; Pearl, RG | 1 |
Biffl, WL; Moore, EE | 1 |
Atkinson, J; Berkeland, J; Emil, S; Kosi, M | 1 |
Whelan, CJ | 1 |
Battaglia, E; Camussi, G; Lupia, E; Modena, V; Montrucchio, G | 1 |
Bourgain, R; Decuyper, K; van Rossem, K; Vermariën, H | 1 |
Kanazawa, T; Onodera, K; Takanashi, S; Yasugahira, H | 1 |
Egido, J; González, E; Gutierrez, S; Herrero-Beaumont, G; Miguélez, R; Navarro, F; Palacios, I; Sanchez-Pernaute, O | 1 |
Johno, M; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
Baker, RR; Siegel, A | 1 |
Fujimura, M; Matsuda, T; Myou, S; Songür, N; Tsujiura, M | 1 |
Hauptmann, S; Kirkpatrick, CJ; Klosterhalfen, B; Küpper, W; Offner, FA; Tietze, L; Töns, C | 1 |
Williams, FM | 1 |
Canarelli, JP; Cordonnier, C; de Boissieu, D; Dupont, C; Léké, A; Postel, JP; Richard, S; Tarrade, T | 1 |
Chang, TW | 1 |
Boku, Y; Fujii, T; Hongo, H; Kondo, M; Nakahashi, Y; Takano, H; Yamaguchi, T; Yamamoto, H; Yanagisawa, R; Yoshida, N; Yoshikawa, T | 1 |
Davamony, D; Jung, TT; Long, SA; Park, YS; Rhee, CK | 1 |
Fitzpatrick, JH; Gilboe, DD; Kintner, DB | 1 |
Oh-ishi, S | 1 |
Berend, N; Matheson, MJ; McClean, MA; Rynell, AC | 1 |
Hellewell, PG; Jeffery, PK; Miotla, JM | 1 |
Ansley, DM; English, JC; Godin, DV; Kim, CW; Lee, JU; Loucks, EB; Qayumi, AK | 1 |
Abdullaev, RIu; Gedymin, LE; Kaminskaia, GO | 2 |
Inagaki, N; Koda, A; Nagai, H; Ueno, M | 1 |
Bhagat, L; Bhatia, M; Frossard, JL; Hofbauer, B; Lee, HS; Saluja, AK; Steer, ML | 1 |
Bussolati, B; Camussi, G; Ghisolfi, G; Lupia, E; Montrucchio, G; Rizea-Savu, S; Sapino, A; Silvestro, L | 1 |
Gillespie, K; Jamieson, WR; Marier, JR; McGibbon, R; Mickleson, H; Sadeghi, H; Zhang, J | 1 |
Higure, A; Itoh, H; Katoh, H; Nagafuchi, Y; Nakamura, S; Ohsato, K; Okamoto, K; Okazaki, K; Takeda, S; Todoroki, H | 1 |
Aliberti, JC; Gazzinelli, RT; Machado, FS; Silva, JS; Teixeira, MM | 1 |
Backer, CL; Crawford, SE; Gonzalez-Crussi, F; Hsueh, W; Huang, L; Liu, H; Mavroudis, C; Mu, Y; Takami, H | 1 |
Ekiz, F; Fincan, K; Haklar, G; Köksoy, F; Soybir, G; Yalçin, O; Yüksel, M | 1 |
Baker, KE; Curtis, MJ | 1 |
Li, S; Meng, Q; Zhang, L | 1 |
Chi, EY; Dietsch, GN; Henderson, WR; Lu, J; Poole, KM | 1 |
Bulkley, GB; Patel, M; Takada, T; Takano, M; Tien, N; Yamakawa, Y | 1 |
Akuta, K; Kawasaki, H; Manabe, H; Ohmori, K | 1 |
Akiyama, H; Goda, Y; Okunuki, H; Sakushima, J; Sawada, JI; Teshima, R; Toyoda, M | 1 |
Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y | 1 |
Gearing, A; Gendelman, HE; Limoges, J; Persidsky, Y; Rasmussen, J; Zheng, J | 1 |
Beales, IL | 1 |
Hasegawa, T; Iwase, M; Izawa, H; Kitaichi, K; Nagasaka, T; Takagi, K; Wang, L; Yokota, M | 1 |
Ashley, SW; Chandler, CF; Gloor, B; Kau, AW; Lane, JS; McFadden, DW; Reber, HA; Todd, KE | 1 |
Akisu, M; Baka, M; Hüsseyinov, A; Küllahçioğlu Girgin, F; Kültürsay, N | 1 |
Steer, ML | 1 |
Masuhara, K; Miki, H; Nakata, K; Yamasaki, S; Yoshikawa, H | 1 |
Ishii, S; Nagase, T; Ouchi, Y; Shimizu, T; Shindou, H | 1 |
Alessandrini, AL; Ishii, S; Klein, A; Pinho, V; Shimizu, T; Teixeira, MM | 1 |
Bozza, MT; Bozza, PT; Caiado, LF; Castro-Faria-Neto, HC; de Assis, EF; Marathe, GK; McIntyre, TM; Prescott, SM; Silva, AR; Zimmerman, GA | 1 |
Iwahisa, Y; Okamoto, H; Terasawa, M | 1 |
Ben-Bassat, M; Blank, M; Krause, I; Shoenfeld, Y | 1 |
Mori, K; Nishizawa, F; Ozawa, K; Shimahara, Y; Takada, Y; Yamaguchi, T; Yamaoka, Y | 1 |
Doly, M; Droy-Lefaix, MT; Jung, H; Munz, K; Remé, C; Wei, Q | 1 |
Arima, M; Makino, S; Sagara, H; Terashi, Y; Yukawa, T | 2 |
Ais, JG; Gómez-Garre, M; López-Farre, A; López-Novoa, JM; Novo, C; Romeo, JM | 1 |
Leong, LL; Stephens, CJ; Sturm, MJ; Taylor, RR | 1 |
Alison, MR; Antoniw, JW; Garvey, B; Maseri, A; Tippins, JR | 1 |
Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
Iwama, T; Koda, A; Nagai, H; Suda, H | 1 |
Caplan, MS; Hsueh, W; Kelly, A | 1 |
Anglin, CP; Clapp, NK; Fretland, DJ; Gaginella, TS; Hansard, RM; Henke, MA; Walsh, RE; Widomski, DL | 1 |
Blais, D; Forbes, RD; Hruby, ZW; Lowry, RP | 1 |
Baskin, DG; Beck, JC; Braquet, P; Glidden, D; Goodner, CJ; Lernmark, A; Wilson, C; Wilson, D | 1 |
Maric, M; Scott, RB | 1 |
Barrigón, S; Salinas, P | 1 |
Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
Imanishi, N; Morooka, S; Sugasawa, T | 1 |
Buurman, WA; Engelberts, I; van der Linden, CJ; von Asmuth, EJ | 1 |
Carter, EA; Schiffrin, EJ; Trop, M | 1 |
Katayama, T | 1 |
Abendschein, DR; Bergmann, SR; Haskel, EJ; Torr, SR; VonVoigtlander, PF | 1 |
Horie, M; Mase, T; Nagaoka, H; Sakurai, Y; Tomioka, K; Yamada, T | 1 |
Braquet, P; Friedrich, G; Giessler, J; Hirschelmann, R; Madi, S | 1 |
Polonskiĭ, VM | 1 |
Fleisher, LN; Joyce, PB; Olson, NC | 1 |
Pauwels, R | 1 |
Bernabeu, F; Braquet, P; Gómez-Garre, D; López-Farré, A; López-Novoa, JM; Perez-Rodrigo, P; Ramón y Cajal, S | 1 |
Caplan, MS; Hsueh, W | 1 |
Feuerstein, G; Frerichs, KU; Hallenbeck, JM; Lindsberg, PJ; Yue, TL | 1 |
Barnes, PJ; Evans, TW; McCormack, DG | 1 |
Barton, R; Desai, S | 1 |
Hyers, TM; Lagunoff, D; Ohar, JA; Pyle, JA; Waller, KS; Webster, RO | 1 |
Hamano, S; Ikeda, S; Kikuchi, S; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y | 1 |
Bourgain, RH | 1 |
Eyre, P; Ogunbiyi, PO | 1 |
Bigaud, M; Parratt, JR; Wainwright, CL | 1 |
Braquet, P; Bricio, T; Cobo, ME; Egido, J; González, E; Hernando, L; Mampaso, FM; Martínez-Montero, JC; Pirotzky, E | 1 |
Bauer, JA; Conzen, P; Fritz, H; Wurster, K | 1 |
Bazan, NG; Braquet, P; Demerle, C; Hosford, D; Marcheselli, V; Rossowska, M; Spinnewyn, B | 1 |
Hayashi, I; Hayashi, M; Oh-ishi, S; Utsunomiya, I; Yamaki, K | 1 |
Casals-Stenzel, J; Heuer, H | 1 |
Abraham, WM; Garrido, R; Stevenson, JS | 1 |
Breddin, HK; Weichert, W | 1 |
Bienvenu, P; Braquet, M; Ducousso, R; Gerasimo, P; Kergonou, JF; Lavaud, P; Mathieu, J | 1 |
Caravella, SJ; Clark, DA; McNeill, H; Miller, MJ; Mullane, KM | 1 |
Makowka, L; Mazzaferro, V; Ontell, SJ; Ove, P; Starzl, TE; Trager, J | 1 |
Robertson, DN; Smith, GM | 1 |
Bessin, P; Braquet, P; Paubert-Braquet, M; Vargaftig, BB | 1 |
Braquet, P; De Giaccobi, G; Jancar, S; Mariano, M; Mencia-Huerta, JM; Sirois, P | 1 |
Auer, H; Egger, D; Fechter, M; Popper, H | 1 |
Arroyave, JL; Gonzalez-Crussi, F; Hsueh, W | 2 |
Becher, G; Kühn, H; Schewe, T; Schilling, W; Slapke, J | 1 |
Bahr, T; Becker, K; Förster, W; Göres, E; Grupe, R; Lueddeckens, G; Schaper, U; Scheuch, DW | 1 |
Wallace, JL | 1 |
Lagente, V; Steel, G; Vargaftig, B; Wallace, JL; Whittle, BJ | 1 |
Hsueh, W; Sun, XM | 1 |
Csatò, M; Czarnetzki, BM | 1 |
Henderson, B; Higgs, GA; Pettipher, ER | 1 |
de Gaetano, G; Dejana, E; Finesso, M; Gorio, A; Languino, LR; Prosdocimi, M; Tessari, F | 1 |
27 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Disease Models, Animal
Article | Year |
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Role for basophils in systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Basophils; Capillary Permeability; Disease Models, Animal; Humans; Immunoglobulin G; Platelet Activating Factor | 2010 |
Role of platelet-activating factor in the pathophysiology of necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Inflammation Mediators; Intestinal Mucosa; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prognosis; Rats; Risk Assessment; Swine | 2002 |
[Conservative treatment of acute pancreatitis].
Topics: Acute Disease; Adjuvants, Immunologic; Analgesics; Animals; Anti-Bacterial Agents; APACHE; C-Reactive Protein; Cholangiography; Cholangiopancreatography, Endoscopic Retrograde; Clinical Trials as Topic; Disease Models, Animal; Double-Blind Method; Enteral Nutrition; Humans; Imidazoles; Leucine; Multicenter Studies as Topic; Multiple Organ Failure; Pancreatitis; Pancreatitis, Acute Necrotizing; Placebos; Platelet Activating Factor; Prognosis; Protease Inhibitors; Randomized Controlled Trials as Topic; Retrospective Studies; Tomography, X-Ray Computed | 2003 |
Phosphoinositide 3-kinase gamma: kinase-dependent and -independent activities in cardiovascular function and disease.
Topics: Animals; Cardiovascular System; Class Ib Phosphatidylinositol 3-Kinase; Cyclic AMP; Disease Models, Animal; Heart Diseases; Humans; Isoenzymes; Mice; Mice, Transgenic; Myocardial Ischemia; Nitric Oxide; Phenotype; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Receptors, G-Protein-Coupled; Signal Transduction | 2004 |
Acute pancreatitis: models, markers, and mediators.
Topics: Acute Disease; Adult; Animals; Biomarkers; Cytokines; Disease Models, Animal; Humans; Inflammation; Pancreatitis; Platelet Activating Factor | 2005 |
Plasma PAF-acetylhydrolase: an unfulfilled promise?
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Inflammatory Agents; Asthma; Atherosclerosis; Biomarkers; Disease Models, Animal; Humans; Inflammation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Recombinant Proteins; Sepsis | 2006 |
The effect of oxygen and light on the structure and function of the neonatal rat retina.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Fetal Development; Humans; Infant, Newborn; Isoprostanes; Light; Oxygen; Platelet Activating Factor; Rats; Retina; Retinitis Pigmentosa; Retinopathy of Prematurity; Thromboxane A2; Visual Pathways | 2009 |
Immunologic mechanisms of parenchymal lung injury.
Topics: Animals; Arachidonic Acids; Arthus Reaction; Autoimmune Diseases; Biotransformation; Complement System Proteins; Disease Models, Animal; Free Radicals; Humans; Immune Complex Diseases; Lung Diseases; Lymphokines; Platelet Activating Factor | 1984 |
[Animal models of bronchial hyperreactivity].
Topics: Adenosine; Animals; Asthma; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chronic Disease; Cytokines; Dextrans; Disease Models, Animal; Dogs; Guinea Pigs; Inflammation; Leukotrienes; Lipoxygenase; Mast Cells; Ozone; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Tachykinins | 1994 |
Platelet-activating factor antagonists as therapeutic strategy in sepsis.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Humans; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis; Shock, Septic | 1994 |
Animal models of necrotizing enterocolitis.
Topics: Animals; Disease Models, Animal; Enterocolitis, Pseudomembranous; Ileum; Inflammation; Ischemia; Platelet Activating Factor; Reperfusion; Splanchnic Circulation | 1995 |
Platelet-activating factor in septic shock.
Topics: Animals; Disease Models, Animal; Humans; Platelet Activating Factor; Rabbits; Rats; Shock, Septic | 1993 |
Platelet-activating factor, tumor necrosis factor, hypoxia and necrotizing enterocolitis.
Topics: Animals; Disease Models, Animal; Enterocolitis, Pseudomembranous; Humans; Hypoxia; Infant, Newborn; Infant, Premature, Diseases; Mice; Platelet Activating Factor; Rats; Risk Factors; Tumor Necrosis Factor-alpha | 1994 |
Antilipid mediator and antioxidant therapy in adult respiratory distress syndrome.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Epoprostenol; Humans; Inflammation; Intensive Care Units; Leukotrienes; Lipid Peroxidation; Middle Aged; Platelet Activating Factor; Respiratory Distress Syndrome; Thromboxanes; Treatment Failure | 1993 |
Cellular and biomolecular mechanisms of liver ischemia and reperfusion injury.
Topics: Animals; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Endothelium, Vascular; Humans; Ischemia; Liver; Neutrophils; Platelet Activating Factor; Reperfusion Injury | 1994 |
From lung hypersensitivity to bronchial hyperreactivity. What can we learn from studies on animal models?
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; Guinea Pigs; Humans; Lymphocytes; Platelet Activating Factor; Respiratory Hypersensitivity | 1993 |
Splanchnic ischaemia/reperfusion and multiple organ failure.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Rats; Reperfusion Injury; Splanchnic Circulation | 1996 |
Neutrophils and myocardial reperfusion injury.
Topics: Animals; Antibodies; Cell Adhesion Molecules; Complement C5a; Disease Models, Animal; Free Radicals; Humans; Interleukin-8; Leukotriene B4; Myocardial Reperfusion Injury; Myocardial Stunning; Neutrophils; Platelet Activating Factor | 1996 |
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan | 1997 |
[Platelet activating factor as a mediator of lesions of the digestive system].
Topics: Animals; Colitis, Ulcerative; Disease Models, Animal; Humans; Liver Cirrhosis, Experimental; Pancreatitis; Peptic Ulcer; Platelet Activating Factor; Rats | 1990 |
The pharmacology of airway hyperresponsiveness and inflammation.
Topics: Airway Resistance; Animals; Asthma; Autonomic Nervous System; Bronchitis; Disease Models, Animal; Humans; Leukotrienes; Muscle, Smooth; Platelet Activating Factor; Respiratory Hypersensitivity | 1990 |
Necrotizing enterocolitis: role of platelet activating factor, endotoxin, and tumor necrosis factor.
Topics: Animals; Disease Models, Animal; Eicosanoids; Endotoxins; Enterocolitis, Pseudomembranous; Free Radicals; Norepinephrine; Oxygen; Platelet Activating Factor; Rats; Shock, Septic; Tumor Necrosis Factor-alpha | 1990 |
Pharmacological studies of pulmonary anaphylaxis in vitro: a review.
Topics: Anaphylaxis; Animals; Antigens; Cell Separation; Chemotactic Factors, Eosinophil; Disease Models, Animal; Dopamine; Histamine Release; Humans; In Vitro Techniques; Kinins; Lung; Lung Diseases; Mast Cells; Muscle Contraction; Muscle, Smooth, Vascular; Perfusion; Platelet Activating Factor; Prostaglandins; Receptors, Adrenergic, beta; Serotonin; SRS-A; Thromboxanes; Trachea | 1985 |
The role of platelet-activating factor in cerebral ischemia and related disorders.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Ischemic Attack, Transient; Platelet Activating Factor | 1989 |
The role of leukotrienes in allergen-induced late responses in allergic sheep.
Topics: Allergens; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchial Spasm; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Leukotriene B4; Models, Biological; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sheep; SRS-A | 1988 |
Platelet-activating factor: a potential mediator of shock.
Topics: Animals; Disease Models, Animal; Immunoglobulin G; Platelet Activating Factor; Shock; Shock, Septic | 1987 |
Ischemic bowel necrosis induced by platelet-activating factor: an experimental model.
Topics: Animals; Complement Activation; Disease Models, Animal; Endotoxins; Enterocolitis, Pseudomembranous; Intestine, Small; Ischemia; Necrosis; Platelet Activating Factor; Rats | 1988 |
242 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Disease Models, Animal
Article | Year |
---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor.
Topics: Animals; Antioxidants; Aqueous Humor; Arachidonic Acid; Disease Models, Animal; Docosahexaenoic Acids; Edema; Inflammation; Light; Lipid Peroxidation; Macular Degeneration; Male; Mitochondria; Oxidative Stress; Oxylipins; Plastoquinone; Platelet Activating Factor; Rabbits; Retina; Retinal Degeneration | 2020 |
Thermal Burn Injury Generates Bioactive Microvesicles: Evidence for a Novel Transport Mechanism for the Lipid Mediator Platelet-Activating Factor (PAF) That Involves Subcellular Particles and the PAF Receptor.
Topics: Animals; Biopsy; Burns; Cell Line; Cell-Derived Microparticles; Disease Models, Animal; Female; Humans; Keratinocytes; Lipid Metabolism; Mice; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Primary Cell Culture; Receptors, G-Protein-Coupled; Skin | 2020 |
Influence of glucocorticoids on time-of-day-dependent variations in IgE-, histamine-, and platelet-activating factor-mediated systemic anaphylaxis in different mouse strains.
Topics: Anaphylaxis; Animals; Circadian Rhythm; Disease Models, Animal; Glucocorticoids; Histamine; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Platelet Activating Factor; Species Specificity | 2018 |
Protective effect of dexmedetomidine against myocardial ischemia-reperfusion injury in rabbits.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Disease Models, Animal; Endothelin-1; Heart Rate; Hemodynamics; Male; Myocardial Reperfusion Injury; No-Reflow Phenomenon; Platelet Activating Factor; Rabbits; Random Allocation; Reference Values; Reproducibility of Results; Thromboxane A2; Treatment Outcome | 2018 |
[Effects of sleep deprivation induced blood stasis syndrome on platelet activation in rats].
Topics: Animals; Dinoprost; Disease Models, Animal; Hemorheology; Medicine, Chinese Traditional; Platelet Activating Factor; Platelet Activation; Rats; Sleep Deprivation; T-Box Domain Proteins; Thrombosis | 2018 |
Platelets mediate protective neuroinflammation and promote neuronal plasticity at the site of neuronal injury.
Topics: Animals; Blood Platelets; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Encephalitis; Female; Glycolipids; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroimmunomodulation; Neuronal Plasticity; Neurons; Platelet Activating Factor; Serotonin | 2018 |
Maternal high-fat diet results in microbiota-dependent expansion of ILC3s in mice offspring.
Topics: Animals; Animals, Newborn; Diet, High-Fat; Disease Models, Animal; Female; Gastrointestinal Microbiome; Homeodomain Proteins; Humans; Immunity, Innate; Immunosuppressive Agents; Injections, Intraperitoneal; Interleukin-17; Intestinal Mucosa; Lipopolysaccharides; Lymphocytes; Male; Maternal Exposure; Mice; Mice, Knockout; Obesity; Platelet Activating Factor; Pregnancy; Prenatal Exposure Delayed Effects | 2018 |
The therapeutic potential of ginkgolide K in experimental autoimmune encephalomyelitis via peripheral immunomodulation.
Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Cellular Microenvironment; Chemotaxis; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Ginkgolides; Humans; Lactones; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Platelet Activating Factor; T-Lymphocytes, Regulatory; Th1-Th2 Balance; Th17 Cells | 2019 |
Roles of BN52021 in platelet-activating factor pathway in inflammatory MS1 cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Fibrinolytic Agents; G-Protein-Coupled Receptor Kinases; Ginkgolides; Inflammation; Islets of Langerhans; Lactones; Lipopolysaccharides; Mice; p38 Mitogen-Activated Protein Kinases; Phospholipase C beta; Phospholipases A2; Platelet Activating Factor; Protein-Tyrosine Kinases; Signal Transduction | 2013 |
Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.
Topics: Adherens Junctions; Anaphylaxis; Animals; Aorta; beta Catenin; Capillary Permeability; Disease Models, Animal; Endothelial Cells; Enzyme Activation; Gene Deletion; Lung; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Platelet Activating Factor; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Signal Transduction | 2013 |
Cooperative role of endogenous leucotrienes and platelet-activating factor in ischaemia-reperfusion-mediated tissue injury.
Topics: Amidines; Animals; Azepines; Biological Assay; Carbamates; Dermis; Disease Models, Animal; Extravasation of Diagnostic and Therapeutic Materials; Extremities; Inflammation; Leukotriene B4; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Neutrophil Infiltration; Platelet Activating Factor; Platelet Membrane Glycoproteins; Propionates; Quinolines; Rabbits; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Reperfusion Injury; Triazoles | 2013 |
Platelet-activating factor enhances tumour metastasis via the reactive oxygen species-dependent protein kinase casein kinase 2-mediated nuclear factor-κB activation.
Topics: Animals; Blotting, Western; Casein Kinase II; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Enzyme Activation; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; NF-kappa B; Platelet Activating Factor; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction | 2014 |
Inositoylated platelet-activating factor (Ino-C2-PAF) modulates dynamic lymphocyte-endothelial cell interactions and alleviates psoriasis-like skin inflammation in two complementary mouse models.
Topics: Animals; Apoptosis; Cell Communication; Cells, Cultured; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Humans; In Vitro Techniques; Inositol; Intercellular Adhesion Molecule-1; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Platelet Activating Factor; Proto-Oncogene Proteins c-jun; Psoriasis; Transcription Factors; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2014 |
Hematopoietic α7 nicotinic acetylcholine receptor deficiency increases inflammation and platelet activation status, but does not aggravate atherosclerosis.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Aorta; Aortic Diseases; Atherosclerosis; Blood Platelets; Bone Marrow Transplantation; Diet, Western; Disease Models, Animal; Female; Genotype; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Inflammation; Inflammation Mediators; Leukocytes; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Plaque, Atherosclerotic; Platelet Activating Factor; Receptors, LDL; Time Factors | 2015 |
Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective.
Topics: Animals; Arachidonate 12-Lipoxygenase; Blood Platelets; Bronchoalveolar Lavage Fluid; Cell Hypoxia; Chemotaxis, Leukocyte; Disease Models, Animal; Docosahexaenoic Acids; Heterografts; Humans; Hydrochloric Acid; Inflammation; Lung; Male; Metabolomics; Mice; Mice, Inbred BALB C; Molecular Structure; Neutrophils; Platelet Activating Factor; Platelet Transfusion; Recombinant Proteins; Respiratory Distress Syndrome; Thrombin | 2014 |
C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo.
Topics: Animals; C-Reactive Protein; Disease Models, Animal; Edema; Histamine; Inflammation Mediators; Male; Phospholipids; Platelet Activating Factor; Protein Binding; Rats; Rats, Wistar; Recombinant Proteins; Scavenger Receptors, Class E; Serotonin | 2014 |
Quinidine, but not eicosanoid antagonists or dexamethasone, protect the gut from platelet activating factor-induced vasoconstriction, edema and paralysis.
Topics: Animals; Dexamethasone; Disease Models, Animal; Edema; Eicosanoids; Female; Gastrointestinal Diseases; Intestinal Mucosa; Paralysis; Platelet Activating Factor; Protective Agents; Quinidine; Rats; Vasoconstriction | 2015 |
[Serum metabolomics analysis on benign prostate hyperplasia in mice based on liquid chromatography-mass spectrometry].
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Discriminant Analysis; Disease Models, Animal; Erucic Acids; Humans; Hyperplasia; Male; Mass Spectrometry; Metabolomics; Mice; Platelet Activating Factor; Prostate; Serum | 2014 |
Protective effect of high concentration of BN52021 on retinal contusion in cat eyes.
Topics: Animals; Cats; Contusions; Disease Models, Animal; Electroretinography; Eye Injuries; Female; Fibrinolytic Agents; Ginkgolides; Intraocular Pressure; Lactones; Male; Nerve Fibers; Platelet Activating Factor; Retina; Retinal Diseases; Retinal Ganglion Cells; Tomography, Optical Coherence; Tonometry, Ocular | 2015 |
[Pain relieving effect of platelet-activating factor (PAF) antagonists in a bone cancer pain model].
Topics: Animals; Bone Neoplasms; Disease Models, Animal; Femur; Humans; Morphine; Pain; Pain Management; Palliative Care; Platelet Activating Factor | 2015 |
In Vitro Effects of Anti-Glaucomatous Eye Drops on Platelet-Activating Factor and its Metabolism.
Topics: Animals; Disease Models, Animal; Drug Combinations; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sulfonamides; Thiophenes; Timolol | 2017 |
Anti-platelet effects of nimesulide in isoproterenol-induced myocardial ischaemia and infarction in rabbits.
Topics: Animals; Disease Models, Animal; Isoproterenol; Myocardial Infarction; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Rabbits; Sulfonamides; Sympathomimetics; Treatment Outcome | 2015 |
Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.
Topics: Animals; Bicarbonates; Burns; Capillary Permeability; Disease Models, Animal; Dogs; Fluid Therapy; Fluorescein-5-isothiocyanate; Glucose; Hemodynamics; Lactic Acid; Platelet Activating Factor; Potassium Chloride; Pyruvic Acid; Random Allocation; Shock; Sodium Chloride; Vascular Endothelial Growth Factor A | 2016 |
Erythrocyte deformability - A partner of the inflammatory response.
Topics: Abdominal Muscles; Animals; Blood Viscosity; Disease Models, Animal; Endothelial Cells; Erythrocyte Deformability; Erythrocytes; Inflammation; Intravital Microscopy; Leukocyte Rolling; Mice, Transgenic; Neutrophils; Nitric Oxide; Platelet Activating Factor; Regional Blood Flow; Stress, Mechanical; Time Factors; Venules | 2016 |
Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism.
Topics: Animals; Blood Platelets; Dendritic Spines; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Humans; Limbic Lobe; Mice; Neuronal Plasticity; Neurons; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled | 2016 |
Glutamine Prevents Late-Phase Anaphylaxis via MAPK Phosphatase 1-Dependent Cytosolic Phospholipase A2 Deactivation.
Topics: Anaphylaxis; Animals; Disease Models, Animal; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Glutamine; Leukotriene B4; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Phosphorylation; Platelet Activating Factor; RNA, Small Interfering | 2016 |
Peroxisome proliferator-activated receptor-alpha reduces inflammation and vascular leakage in a murine model of acute lung injury.
Topics: Acute Lung Injury; Animals; Capillaries; Disease Models, Animal; Endotoxins; Inflammation; Lipopolysaccharides; Mice; Mice, Transgenic; Peroxisome Proliferators; Platelet Activating Factor; PPAR alpha; Pressure; Pulmonary Artery; Pyrimidines | 2008 |
Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity.
Topics: Amylases; Animals; Azepines; Capillaries; Cell Adhesion; Ceruletide; Disease Models, Animal; Edema; Female; Glycodeoxycholic Acid; Leukocytes; Microcirculation; Oligopeptides; Pancreas; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Severity of Illness Index; Taurocholic Acid; Time Factors; Triazoles | 2009 |
Association between the efficacy of dual antiplatelet therapy and the development of in-stent neointimal hyperplasia in porcine coronary arteries.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Aspirin; Cell Proliferation; Clopidogrel; Collagen; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Fibrin; Hyperplasia; Inflammation Mediators; Metals; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Swine; Ticlopidine; Time Factors; Tunica Intima | 2008 |
Platelet-activating factor induces the processing of nuclear factor-kappaB p105 into p50, which mediates acute bowel injury in mice.
Topics: Animals; Chemokine CXCL2; Disease Models, Animal; Hypotension; I-kappa B Proteins; Ileum; Inflammation Mediators; Inflammatory Bowel Diseases; Mice; Mice, Knockout; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Platelet Activating Factor; Protein Processing, Post-Translational; Splanchnic Circulation; Time Factors; Tumor Necrosis Factors; Up-Regulation | 2009 |
GM2 activator protein inhibits platelet activating factor signaling in rats.
Topics: Animals; Disease Models, Animal; Enterocolitis, Necrotizing; G(M2) Activator Protein; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction | 2009 |
Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders.
Topics: AIDS Dementia Complex; Animals; Anti-Inflammatory Agents; Brain; Cell Death; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Focal Adhesion Kinase 2; Giant Cells; Gliosis; Humans; Immunologic Factors; Inflammation Mediators; Male; Mice; Mice, SCID; Microglia; Monocytes; NF-kappa B; Piperazines; Platelet Activating Factor | 2009 |
[Influence of intensive insulin therapy on the intestinal microcirculatory dysfunction in rats with sepsis].
Topics: Animals; Disease Models, Animal; Epoprostenol; Insulin; Intestinal Mucosa; Intestines; Male; Microcirculation; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis; Thromboxane A2 | 2009 |
A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acetyl Coenzyme A; Animals; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Hypoglycemic Agents; Lysophosphatidylcholines; Male; Mice; Platelet Activating Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transfection | 2009 |
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Leukotriene B4; Male; Mast Cells; Ovalbumin; Peritoneal Cavity; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 2010 |
Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Ganglia, Spinal; Inflammation Mediators; Injections; Interleukin-1beta; Lipoxygenase Inhibitors; Mice; Models, Biological; Pain; Peripheral Nerve Injuries; Peripheral Nerves; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Touch; Tumor Necrosis Factor-alpha; Up-Regulation | 2010 |
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Models, Animal; Female; Humans; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Pentanoic Acids; Platelet Activating Factor; Propionates; Rats; Substrate Specificity; Zymosan | 2010 |
Alpha2-adrenergic receptors and their core involvement in the process of axonal growth in retinal explants.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Autoradiography; Axons; Brimonidine Tartrate; Clonidine; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique, Indirect; Glaucoma; Glial Fibrillary Acidic Protein; Optic Nerve Injuries; Organ Culture Techniques; Platelet Activating Factor; Protein Disulfide-Isomerases; Proteomics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Laminin; Retina; Retinal Degeneration; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Platelet-activating factor receptor plays a role in lung injury and death caused by Influenza A in mice.
Topics: Animals; Apoptosis; Blotting, Western; Chickens; Dihydropyridines; Disease Models, Animal; Inflammation Mediators; Influenza A Virus, H1N1 Subtype; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orthomyxoviridae Infections; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Toll-Like Receptors; Viral Load | 2010 |
Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/ PAF acetylhydrolase.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Apolipoproteins E; Biological Transport; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Humans; Hydrolysis; Hyperlipidemias; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled | 2011 |
Platelet-activating factor receptor antagonism targets neuroinflammation in experimental epilepsy.
Topics: Animals; Cell Death; Cytokines; Dihydropyridines; Dinoprostone; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2011 |
The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Aza Compounds; Azo Compounds; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Platelet Activating Factor; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2012 |
Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.
Topics: Animals; Bacterial Proteins; Blood Coagulation; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Disease Models, Animal; Epithelial Cells; Female; Fibrin; Humans; Immunohistochemistry; Macrophages; Mice; Mutation; Plasminogen Activator Inhibitor 1; Platelet Activating Factor; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Alveoli; Respiratory Mucosa; RNA, Messenger; Sepsis; Time Factors; Up-Regulation | 2011 |
Multidrug strategies are effective in the treatment of severe experimental pancreatitis.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Dextrans; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats | 2012 |
Synthetic biotinylated peptide compounds derived from Asp-hemolysin: novel potent inhibitors of platelet-activating factor.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biotin; Biotinylation; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Fungal Proteins; Hemolysin Proteins; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Peptide Fragments; Peptides; Platelet Activating Factor; Rats; Rats, Wistar | 2012 |
[Changes of prostaglandin D2,carboxypeptidase A3 and platelet activating factor in guinea pig in anaphylactic shock].
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anaphylaxis; Animals; Brain; Carboxypeptidases; Case-Control Studies; Disease Models, Animal; Egg Proteins; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Leukotriene E4; Male; Mice; Platelet Activating Factor; Prostaglandin D2; Time Factors | 2012 |
Lipoxin A₄ inhibits platelet-activating factor inflammatory response and stimulates corneal wound healing of injuries that compromise the stroma.
Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Corneal Stroma; Dihydropyridines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Injuries; Fibronectins; Fluorescent Antibody Technique, Indirect; Interleukin-1alpha; Lipoxins; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Wound Healing | 2012 |
The current state of play of rodent models to study the role of vitamin D in UV-induced immunomodulation.
Topics: Animals; Antimicrobial Cationic Peptides; Disease Models, Animal; Epigenesis, Genetic; Immunomodulation; Immunosuppression Therapy; Mice; Mice, Knockout; Platelet Activating Factor; Skin; Ultraviolet Rays; Vitamin D; Vitamin D Deficiency | 2012 |
Urease and Helicobacter spp. antigens in pulmonary granuloma.
Topics: Administration, Oral; Adult; Animals; Antigens, Bacterial; Disease Models, Animal; Female; Gastroesophageal Reflux; Granuloma; Helicobacter pylori; Humans; Interleukin-1beta; Lung; Lung Diseases; Lymphocytes; Male; Middle Aged; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sarcoidosis, Pulmonary; Urease | 2013 |
Leishmania parasites possess a platelet-activating factor acetylhydrolase important for virulence.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Disease Models, Animal; Endoplasmic Reticulum; Gene Deletion; Leishmania major; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Phospholipids; Platelet Activating Factor; Virulence; Virulence Factors | 2012 |
Lesson from acute experimental pancreatitis: multidrug strategies is effective than single-target therapy.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Gabexate; Humans; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreas; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats; Survival Analysis; Survival Rate; Treatment Outcome | 2012 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |
Pain-releasing action of platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Male; Mice; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Spinal Cord | 2013 |
Leukotriene B(4) induces nitric oxide synthesis in Trypanosoma cruzi-infected murine macrophages and mediates resistance to infection.
Topics: Animals; Benzopyrans; Carboxylic Acids; Cells, Cultured; Chagas Disease; Disease Models, Animal; Female; Immunity, Innate; Interferon-gamma; Leukotriene B4; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Platelet Activating Factor; Receptors, Leukotriene B4; Time Factors; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2002 |
Platelet-activating factor-induced pulmonary edema is partly mediated by prostaglandin E(2), E-prostanoid 3-receptors, and potassium channels.
Topics: Animals; Culture Techniques; Dinoprostone; Disease Models, Animal; Female; Mice; Platelet Activating Factor; Potassium Channels; Probability; Pulmonary Edema; Rats; Rats, Wistar; Receptors, Prostaglandin E; Reference Values; Sensitivity and Specificity | 2002 |
Platelet aggregating response to platelet activating factor participates in activation of the 12-lipoxygenase pathway in platelets from rabbits.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arteries; Blood Platelets; Collagen; Disease Models, Animal; In Vitro Techniques; Male; Norepinephrine; Platelet Activating Factor; Platelet Aggregation; Rabbits; Signal Transduction; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Involvement of platelet-activating factor in hepatic apoptosis and necrosis in chronic ethanol-fed rats given endotoxin.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Therapy, Combination; Escherichia coli; Ethanol; Fas Ligand Protein; fas Receptor; Hepatitis, Alcoholic; Immunoenzyme Techniques; In Situ Nick-End Labeling; Isoquinolines; Lipopolysaccharides; Liver; Male; Membrane Glycoproteins; Necrosis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines | 2002 |
Effect of a platelet-activating factor antagonist, E5880, on cerebrovasospasm following subarachnoid hemorrhage in a canine double-hemorrhage model.
Topics: Animals; Basilar Artery; Cerebrovascular Circulation; Disease Models, Animal; Dogs; Female; Male; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Subarachnoid Hemorrhage; Time Factors; Vasoconstriction; Vasospasm, Intracranial | 2002 |
Influence of acyl and plasmalogenic analogs of platelet activating factor on chemotaxis of human leukocytes in vitro and their inflammatory and antiinflammatory activity in vivo.
Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cattle; Chemotaxis, Leukocyte; Disease Models, Animal; Edema; Hindlimb; Humans; Inflammation; Leukocytes; Plasmalogens; Platelet Activating Factor; Rats; Rats, Wistar; Time Factors | 2002 |
Platelet-activating factor, a critical mediator in the pathogenesis of dextran sulfate sodium-induced colitis in rats.
Topics: Analysis of Variance; Animals; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Interleukin-8; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Wistar; RNA, Messenger; Statistics, Nonparametric; Tumor Necrosis Factor-alpha; Up-Regulation | 2003 |
Thymoquinone protects against experimental colitis in rats.
Topics: Acetic Acid; Animals; Benzoquinones; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Histamine; Male; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Rectum | 2003 |
Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Imidazoles; Intestinal Diseases; Intestines; Lung Diseases; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reperfusion Injury | 2003 |
Comment on "Low-dose ethanol alters the cardiovascular, metabolic, and respiratory compensation for severe blood loss".
Topics: Alcoholic Intoxication; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Hemodynamics; Metabolism; Platelet Activating Factor; Research Design; Respiration; Shock, Hemorrhagic; Survival Analysis | 2003 |
An experimental model of hemolysis-induced acute pancreatitis.
Topics: Acute Disease; Amylases; Anemia, Hemolytic; Animals; Disease Models, Animal; Hemolysis; Lipase; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2003 |
Induction of tissue factor in the arterial wall during recurrent thrombus formation.
Topics: Animals; Blood Platelets; Carotid Arteries; Carotid Artery Thrombosis; Carotid Stenosis; Disease Models, Animal; In Situ Hybridization; Monocytes; Muscle, Smooth, Vascular; Neutrophils; Platelet Activating Factor; Platelet-Derived Growth Factor; Rabbits; Recurrence; Regional Blood Flow; RNA, Messenger; Thromboplastin; Tunica Intima; Tunica Media | 2003 |
The role of platelet activating factor and the efficacy of apafant ophthalmic solution in experimental allergic conjunctivitis.
Topics: Animals; Antigens; Azepines; Capillary Permeability; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Dye Dilution Technique; Guinea Pigs; Humans; Immunization, Passive; Ketotifen; Male; Ophthalmic Solutions; Platelet Activating Factor; Pruritus; Time Factors; Triazoles | 2003 |
Airway eosinophil accumulation on sensory neuropeptide release in a guinea pig model of distilled-water-induced bronchoconstriction.
Topics: Aerosols; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Disease Models, Animal; Eosinophils; Guinea Pigs; Immunization, Passive; Male; Methacholine Chloride; Piperidines; Platelet Activating Factor; Quinuclidines; Substance P; Water | 2003 |
The role of dietary supplementation with L-glutamine in inflammatory mediator release and intestinal injury in hypoxia/reoxygenation-induced experimental necrotizing enterocolitis.
Topics: Administration, Oral; Animals; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enterocolitis, Necrotizing; Glutamine; Hypoxia; Intestinal Mucosa; Intestines; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Random Allocation; Tumor Necrosis Factor-alpha | 2003 |
A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4.
Topics: Animals; Blotting, Western; Disease Models, Animal; Female; Immunohistochemistry; Inflammation; Lipopolysaccharides; Membrane Glycoproteins; Mice; Obstetric Labor, Premature; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Pregnancy; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors; Uterus | 2003 |
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2004 |
Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Immunoglobulin E; Leukotrienes; Lung; Male; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled | 2004 |
PAF is involved in the Mycoplasma arthritidis superantigen-triggering pathway for iNOS and COX-2 expression in murine peritoneal cells.
Topics: Animals; Antigens; Antigens, Bacterial; Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Isoenzymes; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C3H; Mitogens; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peritoneum; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Proteins; Signal Transduction; Superantigens; Up-Regulation | 2004 |
Dynamics of PAF-induced conjunctivitis reveals differential expression of PAF receptor by macrophages and eosinophils in the rat.
Topics: Administration, Topical; Animals; Conjunctivitis; Disease Models, Animal; Eosinophils; Immunoenzyme Techniques; Macrophages; Male; Microscopy, Confocal; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred BN; Receptors, G-Protein-Coupled; Time Factors | 2004 |
Captopril suppresses post-transplantation angiogenic activity in rat allograft coronary vessels.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Culture Techniques; Cell Movement; Cornea; Coronary Artery Disease; Disease Models, Animal; Endothelial Cells; Heart Transplantation; Male; Neovascularization, Physiologic; Platelet Activating Factor; Rats; Rats, Inbred F344; Rats, Inbred Lew; Vascular Endothelial Growth Factor A | 2004 |
Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis.
Topics: Animals; Chemokine CCL4; Chemokine CXCL2; Conjunctiva; Conjunctivitis; Cytokines; Disease Models, Animal; Eosinophil Major Basic Protein; Eosinophilia; Eosinophils; Macrophage Inflammatory Proteins; Male; Microscopy, Confocal; Monokines; Myelin Basic Protein; Nerve Tissue Proteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred BN; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2005 |
In vivo PAF-induced airway eosinophil accumulation reduces bronchial responsiveness to inhaled histamine.
Topics: Administration, Inhalation; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Guanidines; Guinea Pigs; Histamine; Male; Platelet Activating Factor | 2005 |
Individual and combined effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on endotoxin-induced periodontitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Endotoxins; Fatty Acids, Omega-3; Leukotriene B4; Male; Periodontitis; Platelet Activating Factor; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2005 |
The inositol trisphosphate pathway mediates platelet-activating-factor-induced pulmonary oedema.
Topics: Animals; Calcium; Disease Models, Animal; Endothelium; Female; Inositol 1,4,5-Trisphosphate; Intracellular Signaling Peptides and Proteins; Lung; Myosin-Light-Chain Kinase; Organ Size; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pulmonary Edema; Rats; Rats, Wistar; Reference Values; rho-Associated Kinases | 2005 |
Rat model of platelet-activating factor-induced rhinosinusitis.
Topics: Administration, Intranasal; Animals; Autacoids; Disease Models, Animal; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rhinitis; Sinusitis | 2005 |
Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro.
Topics: Animals; Annexin A1; CD11b Antigen; Chemotaxis; Disease Models, Animal; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Muscle, Skeletal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Time Factors; Zymosan | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytosol; Disease Models, Animal; Enzyme Activation; Histamine; Inflammation; Leukotriene B4; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Phospholipases A; Platelet Activating Factor; Pulmonary Eosinophilia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Anti-allergic properties of the bromeliaceae Nidularium procerum: inhibition of eosinophil activation and influx.
Topics: Animals; Anti-Allergic Agents; Asthma; Bromeliaceae; Bronchoalveolar Lavage Fluid; Cell Movement; Cells, Cultured; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Female; Inclusion Bodies; Inflammation Mediators; Interleukin-13; Lipid Metabolism; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Ovalbumin; Plant Extracts; Plant Leaves; Platelet Activating Factor; Pleurisy; Pulmonary Eosinophilia; Spleen; Time Factors | 2005 |
Pharmacological profile of PMS777, a new AChE inhibitor with PAF antagonistic activity.
Topics: Acetylcholinesterase; Animals; Binding, Competitive; Brain; Butyrylcholinesterase; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Male; Maze Learning; Memory; Memory Disorders; Mice; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, G-Protein-Coupled; Scopolamine; Space Perception | 2007 |
In vivo antiatherogenic properties of olive oil and its constituent lipid classes in hyperlipidemic rabbits.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Aorta; Atherosclerosis; Diet, Atherogenic; Disease Models, Animal; Hyperlipidemias; Lipoproteins; Male; Olive Oil; Oxidation-Reduction; Plant Oils; Platelet Activating Factor; Platelet Aggregation; Rabbits | 2006 |
Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Bacterial Agents; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Male; Mice; Middle Aged; Platelet Activating Factor; Systemic Inflammatory Response Syndrome | 2006 |
Mechanism for acute oral desensitization to antibiotics.
Topics: Administration, Oral; Anaphylaxis; Animals; Anti-Bacterial Agents; Desensitization, Immunologic; Disease Models, Animal; Drug Hypersensitivity; Female; Histamine; Immunoglobulin E; Mast Cells; Mice; Penicillin V; Platelet Activating Factor | 2006 |
The effects of Gingko biloba extract on acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Antioxidants; Biomarkers; Colitis; Disease Models, Animal; Fibrosis; Ginkgo biloba; Intestinal Mucosa; Male; Malondialdehyde; Necrosis; Oxidative Stress; Phytotherapy; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar | 2006 |
Effects of intracerebroventricular injections of free fatty acids, lysophospholipids, or platelet activating factor in a mouse model of orofacial pain.
Topics: Animals; Carrageenan; Disease Models, Animal; Drug Therapy, Combination; Facial Pain; Fatty Acids, Nonesterified; Injections, Intraventricular; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Pain Measurement; Platelet Activating Factor; Time Factors | 2006 |
[Effect of changes in airway pressure and the inspiratory volume on the fluid filtration rate and pulmonary artery pressure in isolated rabbit lungs perfused with blood and acellular solution].
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Data Interpretation, Statistical; Disease Models, Animal; Fenoterol; Filtration; Lung; Platelet Activating Factor; Positive-Pressure Respiration; Pulmonary Artery; Pulmonary Atelectasis; Pulmonary Circulation; Pulmonary Edema; Rabbits; Respiratory Mechanics; Tidal Volume | 2006 |
Down-regulation of platelet-activating factor receptor gene expression during focal reversible cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Disease Models, Animal; DNA Primers; Down-Regulation; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion; RNA, Messenger | 2007 |
Platelet-activating factor antagonist (ABT-491) decreases neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspase 3; Cell Count; Disease Models, Animal; Drug Administration Schedule; Hypoxia-Ischemia, Brain; Imidazoles; In Situ Nick-End Labeling; Indoles; Platelet Activating Factor; Rats | 2007 |
Role of platelet-activating factor in pneumolysin-induced acute lung injury.
Topics: Animals; Bacterial Proteins; Disease Models, Animal; Female; Humans; Hypertension, Pulmonary; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pneumonia, Pneumococcal; Protein Serine-Threonine Kinases; Respiratory Distress Syndrome; rho-Associated Kinases; Signal Transduction; Streptolysins; Thromboxane A2 | 2007 |
[Effects of bificobacterium longum on neonatal rat model of necrotizing enterocolitis and roles of platelet-activating factor and tumor necrosis factor-alpha].
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Female; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sulfalene; Tumor Necrosis Factor-alpha | 2007 |
Acute lung injury in a rat model of intestinal ischemia-reperfusion: the potential time depended role of phospholipases A(2).
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Intestines; Lung; Male; Malondialdehyde; Phospholipases A2; Platelet Activating Factor; Pulmonary Gas Exchange; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Respiratory Distress Syndrome; Time Factors | 2008 |
Synthesis of platelet-activating factor and its receptor expression in Kupffer cells in rat carbon tetrachloride-induced cirrhosis.
Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Endothelin-1; Kupffer Cells; Liver Cirrhosis; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, G-Protein-Coupled; RNA, Messenger | 2008 |
A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.
Topics: Animals; Calcium; Calcium Signaling; Cell Shape; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Ginkgolides; Lactones; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar; Time Factors; Ventricular Function, Left | 2008 |
Experimental model of ischemic bowel necrosis. The role of platelet-activating factor and endotoxin.
Topics: Animals; Disease Models, Animal; Endotoxins; Enterocolitis, Pseudomembranous; Gastric Mucosa; Ileum; Intestine, Large; Jejunum; Male; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains | 1983 |
Rat serum sickness: possible role of inflammatory mediators allowing deposition of immune complexes in the glomerular basement membrane.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Basement Membrane; Disease Models, Animal; Histamine; Kidney Glomerulus; Ovalbumin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Sickness | 1982 |
Protective effects of L-659,989, a platelet-activating factor receptor antagonist, in myocardial ischemia and reperfusion in rats.
Topics: Animals; Creatine Kinase; Disease Models, Animal; Furans; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Survival Rate | 1994 |
Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Arachidonic Acid; Carrageenan; Cell Degranulation; Crotoxin; Disease Models, Animal; Edema; Guinea Pigs; Histamine Release; Humans; Injections, Intraperitoneal; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Wistar; Serotonin; Thromboxane B2 | 1995 |
The effect of platelet activating factor antagonist (BN 52021) on acute experimental pancreatitis with reference to multiorgan oxidative stress.
Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Liver; Lung; Male; Malondialdehyde; Organ Specificity; Oxidative Stress; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Sulfhydryl Compounds | 1995 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig.
Topics: Acute Disease; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Histamine; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mifepristone; Neutrophils; Platelet Activating Factor; Pneumonia; Skin | 1995 |
SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Arachidonic Acid; Cell-Free System; Disease Models, Animal; Enzyme Inhibitors; Humans; Leukotriene B4; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic; Sulfonamides; Survivors | 1995 |
Effect of YM264 on the airway hyperresponsiveness and the late asthmatic response in a guinea pig model of asthma.
Topics: Aerosols; Airway Resistance; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; Immunization; Male; Ovalbumin; Piperazines; Platelet Activating Factor; Random Allocation; Statistics, Nonparametric; Thiazoles; Thiazolidines; Time Factors; Trachea | 1995 |
Mast cell mediators and peritoneal adhesion formation in the rat.
Topics: Animals; Azepines; Disease Models, Animal; Histamine Antagonists; Leukotriene D4; Male; Mast Cells; Methysergide; Ondansetron; Peritoneal Diseases; Platelet Activating Factor; Propionates; Pyrilamine; Quinolines; Ranitidine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tissue Adhesions; Triazoles | 1995 |
Contribution of platelet activating factor (PAF) in histamine-induced model of nasal allergy in rats.
Topics: Animals; Disease Models, Animal; Histamine; Male; Nasal Mucosa; Permeability; Platelet Activating Factor; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial | 1995 |
Endothelin-1 induces neutrophil-independent vascular injury in the rat gastric microcirculation.
Topics: Animals; Azepines; Capillary Permeability; Disease Models, Animal; Endothelins; Endothelium, Vascular; Gastric Mucosa; Infusions, Intra-Arterial; Isotope Labeling; Male; Methacrylates; Neutrophils; Platelet Activating Factor; Rats; Rats, Wistar; Serum Albumin; Stomach Ulcer; Thromboxane-A Synthase; Triazoles | 1995 |
Platelet-activating factor antagonist and cardiopulmonary bypass.
Topics: Animals; Atrial Function, Left; Blood Pressure; Cardiopulmonary Bypass; Disease Models, Animal; Diterpenes; Fibrinolytic Agents; Ginkgolides; Humans; Lactones; Lung; Platelet Activating Factor; Pulmonary Artery; Swine; Vascular Resistance | 1995 |
Increase in respiratory resistance after exercise in conscious guinea pigs. As a model for exercise-induced asthma.
Topics: Airway Resistance; Animals; Asthma, Exercise-Induced; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; Interleukin-5; Ketotifen; Lipopolysaccharides; Male; Metyrapone; Physical Exertion; Platelet Activating Factor; Prednisolone | 1995 |
Effects of TCV-309, a novel PAF antagonist, on circulatory shock and hematological abnormality induced by endotoxin in dogs.
Topics: Animals; Blood Circulation; Blood Pressure; Disease Models, Animal; Dogs; Heart; Hematologic Diseases; Hemodynamics; Isoquinolines; Male; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines; Time Factors | 1994 |
WEB-2086 and indomethacin do not modify blood pressure fall on unclipping hypertensive rats.
Topics: Animals; Azepines; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Indomethacin; Injections, Intravenous; Male; Platelet Activating Factor; Rats; Rats, Wistar; Renal Artery; Triazoles | 1994 |
Platelet-activating factor causes venular constriction in the microcirculation.
Topics: Animals; Cheek; Cricetinae; Disease Models, Animal; Edema; Hemodynamics; Male; Mesocricetus; Platelet Activating Factor; Vasoconstriction; Venules | 1994 |
Cytokine gene and peptide regulation in lung microvascular injury: new insights on the development of adult respiratory distress syndrome.
Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Drug Synergism; Lipopolysaccharides; Lung; Platelet Activating Factor; Rats; Respiratory Distress Syndrome; RNA, Messenger; Tumor Necrosis Factor-alpha | 1994 |
Platelet-activating factor augments meningeal inflammation elicited by Haemophilus influenzae lipooligosaccharide in an animal model of meningitis.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Female; Lipopolysaccharides; Meningitis, Haemophilus; Platelet Activating Factor; Rats; Rats, Wistar | 1994 |
Leukocytes and the inflammatory response.
Topics: Adhesiveness; Age Factors; Animals; Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion Molecules; Cell Movement; Disease Models, Animal; Endothelium; Humans; Infant, Newborn; Inflammation; Interleukin-8; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Reperfusion Injury; Respiratory Distress Syndrome | 1993 |
Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees.
Topics: alpha 1-Antitrypsin; Animals; Cytokines; Disease Models, Animal; Endotoxins; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Interleukin-8; Isoquinolines; Leukocyte Count; Leukocyte Elastase; Neutrophils; Pan troglodytes; Pancreatic Elastase; Platelet Activating Factor; Pyridinium Compounds; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tetrahydroisoquinolines; Toxemia; Tumor Necrosis Factor-alpha | 1994 |
Endogenous nitric oxide protects against platelet-activating factor-induced bowel injury in the rat.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hematocrit; Intestines; Male; Mesenteric Artery, Superior; Necrosis; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Superoxides | 1993 |
Platelet-activating factor-induced ischemic bowel necrosis: the effect of platelet-activating factor acetylhydrolase.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Disease Models, Animal; Enterocolitis, Pseudomembranous; Female; Humans; Infant, Newborn; Intestines; Ischemia; Milk, Human; Necrosis; Phospholipases A; Platelet Activating Factor; Rats; Rats, Wistar | 1993 |
Inflammatory mediator changes in cotton-top tamarins (CTT) after SC-41930 anti-colitic therapy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Benzopyrans; Colitis; Colon; Dinoprostone; Disease Models, Animal; Leukotriene B4; Platelet Activating Factor; Radioimmunoassay; Saguinus; Thromboxane B2 | 1993 |
Effect of CL 184,005, a platelet-activating factor antagonist in a murine model of Staphylococcus aureus-induced gram-positive sepsis.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enterotoxins; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Organophosphorus Compounds; Platelet Activating Factor; Staphylococcal Infections; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Effect of ischaemia and role of eicosanoids in release of atrial natriuretic factor from rat heart.
Topics: Animals; Atrial Natriuretic Factor; Disease Models, Animal; Diterpenes; Eicosanoids; Ginkgolides; Heart Rate; Lactones; Male; Masoprocol; Meclofenamic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred Strains; Secretory Rate | 1993 |
Early release of neutrophil chemotactic factor from isolated rat heart subjected to regional ischaemia followed by reperfusion.
Topics: Animals; Chemotaxis; Disease Models, Animal; Hot Temperature; Interleukin-8; Isoquinolines; Male; Myocardial Reperfusion Injury; Myocardium; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors | 1993 |
Effect of platelet-activating factor on basal and insulin-mediated system A amino acid transport in rat soleus muscle.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Disease Models, Animal; Insulin; Inulin; Male; Muscles; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Septic; Sodium | 1993 |
Inhibitory effect of TCV-309, a novel platelet activating factor (PAF) antagonist, on endotoxin-induced disseminated intravascular coagulation in rats: possible role of PAF in tissue factor generation.
Topics: Animals; Disease Models, Animal; Disseminated Intravascular Coagulation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Isoquinolines; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Thromboplastin | 1993 |
The effect of a platelet activating factor antagonist (BN 52021) on neurologic outcome and histopathology in a canine model of complete cerebral ischemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Injections, Intravenous; Lactones; Platelet Activating Factor | 1993 |
Protective effect of the PAF antagonist BN 52021 in an experimental renal warm ischemia model.
Topics: Animals; Creatinine; Disease Models, Animal; Diterpenes; Ginkgolides; Hypertonic Solutions; Infusions, Intravenous; Infusions, Parenteral; Kidney Diseases; Kidney Function Tests; Lactones; Male; Nephrectomy; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion Injury; Sodium | 1993 |
PAF-induced death in NMRI mice--a suitable shock model for testing new PAF receptor antagonists. Correlation with eicosanoid related substances.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Disease Models, Animal; Diterpenes; Eicosanoids; Female; Ginkgolides; Lactones; Masoprocol; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock; Species Specificity; Triazoles | 1993 |
Effect of nedocromil sodium on specific mediator- and antigen-induced airway responses in allergic sheep.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Helminth; Ascaris; Bradykinin; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Drug Evaluation, Preclinical; Nedocromil; Platelet Activating Factor; Quinolones; Respiratory Hypersensitivity; Sheep; Time Factors | 1993 |
Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Movement; Disease Models, Animal; Free Radical Scavengers; Gastric Acid; Gastric Mucosa; Gastritis; Isoquinolines; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Vasoconstriction | 1993 |
Bronchopulmonary responses to endothelin-1 in sensitized and challenged guinea-pigs: role of cyclooxygenase metabolites and platelet-activating factor.
Topics: Aerosols; Animals; Azepines; Bronchi; Disease Models, Animal; Endothelins; Glycopeptides; Guinea Pigs; Immunization; Indomethacin; Lung; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1993 |
Murine hypersensitivity pneumonitis: evidences for the role of eicosanoids and platelet activating factor.
Topics: Alveolitis, Extrinsic Allergic; Animals; Bronchoalveolar Lavage Fluid; Calcimycin; Disease Models, Animal; Eicosanoids; Female; Leukocyte Count; Lymphocytes; Macrophage Activation; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Saccharopolyspora; Specific Pathogen-Free Organisms | 1993 |
Platelet-activating factor and cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Immunoglobulin G; Ischemic Attack, Transient; Lactones; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Subarachnoid Hemorrhage | 1993 |
Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Benzylisoquinolines; Bradykinin; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Histamine; Hypersensitivity; Male; Platelet Activating Factor; Respiratory System; SRS-A | 1993 |
An airway hyperresponsiveness model in rat allergic asthma.
Topics: Acetylcholine; Animals; Ascaris; Asthma; Bronchial Hyperreactivity; Capillary Permeability; Chromones; Depression, Chemical; Dinitrophenols; Disease Models, Animal; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; SRS-A; Thromboxane-A Synthase; Tissue Extracts | 1993 |
ARDS-like lung injury produced by endotoxin in platelet-activating factor-primed rats.
Topics: Animals; Disease Models, Animal; Endotoxins; Hemodynamics; Lipopolysaccharides; Lung; Lung Injury; Male; Microscopy, Electron; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Thromboxane B2; Tumor Necrosis Factor-alpha | 1993 |
Increased brain levels of platelet-activating factor in a murine acquired immune deficiency syndrome are NMDA receptor-mediated.
Topics: AIDS Dementia Complex; Animals; Behavior, Animal; Brain Chemistry; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Platelet Activating Factor; Receptors, N-Methyl-D-Aspartate | 1996 |
Platelet-activating factor in brain regions after transient ischemia in gerbils.
Topics: Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Disease Progression; Female; Gas Chromatography-Mass Spectrometry; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Platelet Activating Factor; Reperfusion; Thalamus | 1996 |
Protective effect of a platelet-activating factor antagonist (WEB-2086) in postischemic renal failure.
Topics: Acute Kidney Injury; Animals; Azepines; Disease Models, Animal; Diuresis; Female; Ischemia; Kidney; Kidney Function Tests; Male; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Triazoles | 1996 |
Plasma potentiates the priming effects of endotoxin on platelet activating factor-induced pulmonary hypertension in the rabbit lung.
Topics: Acute-Phase Proteins; Animals; Blood Pressure; Blood Proteins; Carrier Proteins; Disease Models, Animal; Endotoxins; Escherichia coli; Hypertension, Pulmonary; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Membrane Glycoproteins; Plasma; Platelet Activating Factor; Pulmonary Artery; Rabbits; Respiratory Distress Syndrome; Serum Albumin | 1996 |
Inhaled nitric oxide prevents experimental platelet activating factor-induced shock.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Platelet Activating Factor; Random Allocation; Shock, Septic; Swine | 1996 |
Inhibition of PAF-, LPS-, and cytokine-induced granulocyte accumulation in guinea pig lung by dexamethasone: evidence that inhibition of IL-5 release is responsible for the selective inhibition of eosinophilia by glucocorticoids in guinea-pigs.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Chemokines; Chemotactic Factors; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Growth Inhibitors; Growth Substances; Guinea Pigs; Injections, Intraperitoneal; Interleukin-5; Lipopolysaccharides; Lung; Male; Neutrophils; Platelet Activating Factor; Trachea; Tumor Necrosis Factor-alpha | 1996 |
Role of tumor necrosis factor-alpha and platelet-activating factor in neoangiogenesis induced by synovial fluids of patients with rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Collagen; Disease Models, Animal; Drug Combinations; Female; Humans; Laminin; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neovascularization, Pathologic; Osteoarthritis; Platelet Activating Factor; Proteoglycans; Synovial Fluid; Tumor Necrosis Factor-alpha | 1996 |
The role of PAF and the effect of a specific PAF antagonist on local tissue PO2 and neuronal integrity during and after photothrombotic brain infarction in unanesthetised rabbits.
Topics: Animals; Brain; Cerebral Infarction; Disease Models, Animal; Evoked Potentials, Somatosensory; Male; Neurons; Oxygen Consumption; Photobiology; Platelet Activating Factor; Pyridines; Rabbits; Thiazoles; Time Factors | 1996 |
[The changes of blood gas analysis values and platelet aggregability on acute phase in the experimental model of pulmonary embolism prepared by sephadex G-75 (SG-75) injection].
Topics: Acute-Phase Reaction; Adenosine Diphosphate; Animals; Blood Gas Analysis; Carbon Dioxide; Dextrans; Disease Models, Animal; Male; Oxygen; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pulmonary Embolism; Rabbits | 1996 |
Anti-inflammatory effect of a PAF receptor antagonist and a new molecule with antiproteinase activity in an experimental model of acute urate crystal arthritis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Azepines; C-Reactive Protein; Dinoprostone; Disease Models, Animal; Indenes; Interleukin-6; Joints; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protease Inhibitors; Rabbits; Random Allocation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synovial Fluid; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha; Uric Acid | 1996 |
A novel platelet activating factor antagonist, SM-12502, attenuates endotoxin-induced disseminated intravascular coagulation and acute pulmonary vascular injury by inhibiting TNF production in rats.
Topics: Animals; Blood Coagulation; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Female; Humans; Infant, Newborn; Platelet Activating Factor; Pulmonary Artery; Rats; Rats, Wistar; Respiratory Distress Syndrome, Newborn; Thiazoles; Thiazolidines | 1996 |
Activities of enzymes in platelet activating factor biosynthetic pathways in the gerbil model of cerebral ischemia.
Topics: Acetyltransferases; Adenosine Triphosphate; Animals; Brain Ischemia; Diacylglycerol Cholinephosphotransferase; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Gerbillinae; Palmitoyl-CoA Hydrolase; Platelet Activating Factor | 1996 |
Involvement of PAF in postallergic propranolol-induced bronchoconstriction in guinea-pigs.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Anesthesia, General; Animals; Antigens; Asthma; Azepines; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Hypersensitivity; Immunization; Inflammation Mediators; Injections, Intravenous; Male; Platelet Activating Factor; Propranolol; Respiration, Artificial; Time Factors; Triazoles | 1996 |
Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspartic Acid; Blood Pressure; Cardiac Output; Disease Models, Animal; Endotoxemia; Gene Expression; HSP70 Heat-Shock Proteins; Inflammation Mediators; Interleukin-1; Interleukin-6; Kidney; Lipopolysaccharides; Metallothionein; Platelet Activating Factor; Pulmonary Artery; Recurrence; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha; Zinc | 1996 |
Effect of BN 50727 on pathological findings and tissue platelet activating factor levels during ileal ischemia in newborn piglets.
Topics: Animals; Animals, Newborn; Azepines; Disease Models, Animal; Enterocolitis, Pseudomembranous; Humans; Ileum; Infant, Newborn; Ischemia; Platelet Activating Factor; Swine; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha | 1996 |
Improvement of survival from hemorrhagic shock by enterectomy in rats: finding to implicate the role of the gut for irreversibility of hemorrhagic shock.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Endotoxins; Intestines; Liver; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate; Tumor Necrosis Factor-alpha | 1997 |
Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats.
Topics: Animals; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Injections, Intravenous; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Platelet Activating Factor; Rats; Systemic Inflammatory Response Syndrome | 1997 |
Effects of platelet activating factor on vascular permeability of the middle ear mucosa.
Topics: Animals; Capillary Permeability; Chinchilla; Disease Models, Animal; Ear, Middle; Injections; Mucous Membrane; Otitis Media with Effusion; Platelet Activating Factor | 1997 |
Hyperglycemic damage to mitochondrial membranes during cerebral ischemia: amelioration by platelet-activating factor antagonist BN 50739.
Topics: Animals; Azepines; Blood Pressure; Brain; Disease Models, Animal; Electroencephalography; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Femoral Artery; Hyperglycemia; Intracellular Membranes; Ischemic Attack, Transient; Lipid Peroxidation; Male; Membrane Lipids; Mitochondria; Oxygen Consumption; Phospholipids; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion; Thiobarbituric Acid Reactive Substances; Time Factors; Triazoles | 1997 |
Role of platelet activating factor, leukotrienes and polymorphs in the FMLP induced increase in microvascular leakage in rabbit trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkylating Agents; Animals; Azepines; Bronchitis; Capillary Permeability; Coloring Agents; Disease Models, Animal; Drug Interactions; Evans Blue; Indazoles; Leukotrienes; Male; Mechlorethamine; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rabbits; Reference Values; Trachea; Triazoles; Vasoconstrictor Agents | 1997 |
Platelet-activating factor plays a pivotal role in the induction of experimental lung injury.
Topics: Animals; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Elapid Venoms; Extravascular Lung Water; Female; Humans; Imidazoles; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Serum Albumin; Skin; Zymosan | 1998 |
The role of platelet-activating factor in regional myocardial ischemia-reperfusion injury.
Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Pressure; Cardiac Output; Cardiac Volume; Disease Models, Animal; Female; Heart Arrest; Hemodynamics; Isoquinolines; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Random Allocation; Stroke Volume; Swine; Tetrahydroisoquinolines; Ventricular Fibrillation; Ventricular Function | 1998 |
[Features of oxidative metabolism and level of platelet activating factor in pulmonary and circulating phagocytes of tuberculosis-resistant animals at stages of experimental infection].
Topics: Animals; Biomarkers; Catalase; Disease Models, Animal; Follow-Up Studies; Guinea Pigs; Leukocytes; Macrophages, Alveolar; Malondialdehyde; Oxidative Stress; Platelet Activating Factor; Rats; Superoxide Dismutase; Tuberculosis, Pulmonary | 1998 |
Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen.
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Disease Models, Animal; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity; Ketotifen; Male; Passive Cutaneous Anaphylaxis; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 1998 |
Effect of recombinant platelet-activating factor acetylhydrolase on two models of experimental acute pancreatitis.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acute Disease; Animals; Bile Ducts; Ceruletide; Disease Models, Animal; Gastrointestinal Agents; Ligation; Lung; Lung Diseases; Male; Opossums; Pancreas; Pancreatic Ducts; Pancreatitis; Phospholipases A; Platelet Activating Factor; Rats; Rats, Wistar; Recombinant Proteins | 1998 |
Potential angiogenic role of platelet-activating factor in human breast cancer.
Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Mice; Mice, Inbred C57BL; Middle Aged; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Activating Factor; Tumor Cells, Cultured | 1998 |
Strategies of myocardial protection for operation in chronic model of cyanotic heart disease.
Topics: Animals; Cardiopulmonary Bypass; Chronic Disease; Disease Models, Animal; Filtration; Heart; Heart Arrest, Induced; Heart Defects, Congenital; Injections, Intravenous; Lymphocyte Depletion; Myocardial Contraction; Platelet Activating Factor; Pyridinium Compounds; Swine | 1998 |
Possible role of platelet-activating factor in the in vivo expression of tissue factor in neutrophils.
Topics: Animals; Aspartate Aminotransferases; Blood Coagulation; Cholangitis; Disease Models, Animal; Leukocytes; Liver; Male; Neutrophils; Platelet Activating Factor; Rabbits; Thiazoles; Thiazolidines; Thromboplastin | 1998 |
[Platelet activating factor in biological fluids of animals with different species-specific resistance at the stage of infective process after inoculation with mycobacterium tuberculosis].
Topics: Animals; Biomarkers; Body Fluids; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; Leukocytes; Macrophages, Alveolar; Mycobacterium tuberculosis; Platelet Activating Factor; Rabbits; Rats; Species Specificity; Tuberculosis | 1998 |
Platelet-activating factor induces nitric oxide synthesis in Trypanosoma cruzi-infected macrophages and mediates resistance to parasite infection in mice.
Topics: Animals; Cell Line; Cells, Cultured; Chagas Disease; Disease Models, Animal; Female; Immunity, Innate; Macaca mulatta; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Nitric Oxide; Parasitemia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Trypanocidal Agents; Trypanosoma cruzi | 1999 |
Captopril and platelet-activating factor (PAF) antagonist prevent cardiac allograft vasculopathy in rats: role of endogenous PAF and PAF-like compounds.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Captopril; Coronary Disease; Disease Models, Animal; Drug Therapy, Combination; Heart Transplantation; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Homologous; Treatment Outcome; Triazoles; Ventricular Remodeling | 1999 |
The effects of free oxygen radical scavenger and platelet-activating factor antagonist agents in experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Deferoxamine; Disease Models, Animal; Edema; Free Radical Scavengers; Ginkgo biloba; Inflammation; Leukocytes; Luminescent Measurements; Male; Mice; Pancreas; Pancreatitis; Phytotherapy; Plants, Medicinal; Platelet Activating Factor | 1999 |
Protection against ventricular fibrillation by the PAF antagonist, BN-50739, involves an ischaemia-selective mechanism.
Topics: Animals; Anti-Arrhythmia Agents; Azepines; Disease Models, Animal; Male; Myocardial Ischemia; Perfusion; Platelet Activating Factor; Protective Agents; Rats; Rats, Wistar; Triazoles; Vasodilation; Ventricular Fibrillation | 1999 |
Experimental therapy of a platelet-activating factor antagonist (ginkgolide B) on photochemically induced thrombotic cerebral ischaemia in tree shrews.
Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Intracranial Thrombosis; Lactones; Male; Neuroprotective Agents; Platelet Activating Factor; Tupaiidae | 1999 |
Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Models, Animal; Eosinophils; Female; Humans; Interleukin-5; Lung; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Phospholipases A; Platelet Activating Factor; Recombinant Proteins | 2000 |
Interaction of platelet activating factor, reactive oxygen species generated by xanthine oxidase, and leukocytes in the generation of hepatic injury after shock/resuscitation.
Topics: Animals; Disease Models, Animal; Drug Interactions; Leukocytes; Liver; Male; Oxidative Stress; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic; Time Factors; Xanthine Oxidase | 2000 |
The inhaled administration of KF19514, a phosphodiesterase 4 and 1 inhibitor, prevents antigen-induced lung inflammation in guinea pigs.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Aminophylline; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Disease Models, Animal; Eosinophils; Guinea Pigs; Male; Naphthyridines; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pneumonia; Rolipram; Specific Pathogen-Free Organisms; Vasodilator Agents | 2000 |
Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice.
Topics: Administration, Oral; Anaphylaxis; Animals; Body Weight; Disease Models, Animal; Female; Fever; Food Hypersensitivity; Histamine; Injections, Intraperitoneal; Interferon-gamma; Interleukin-4; Mast Cells; Mice; Mice, Mutant Strains; Organ Size; Ovalbumin; Platelet Activating Factor; Th2 Cells | 2000 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2 | 2001 |
Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis.
Topics: AIDS Dementia Complex; Animals; Benzyl Compounds; Cell Survival; Dexamethasone; Disease Models, Animal; Drug Combinations; Gliosis; HIV-1; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leucine; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, SCID; Microglia; Neurons; Pentoxifylline; Platelet Activating Factor; Protease Inhibitors; Succinates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
Effect of platelet-activating factor on gastrin release from cultured rabbit G-cells.
Topics: Animals; Bombesin; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Disease Models, Animal; Gastrin-Secreting Cells; Gastrins; Gastritis; Helicobacter Infections; Helicobacter pylori; Platelet Activating Factor; Protein Kinase C; Rabbits | 2001 |
Cardiac functional and structural alterations induced by endotoxin in rats: importance of platelet-activating factor.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Echocardiography; Electrocardiography; Endotoxemia; Epinephrine; Hematocrit; Isoquinolines; Klebsiella Infections; Klebsiella pneumoniae; Lipopolysaccharides; Male; Nitrates; Nitrites; Norepinephrine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Rats; Rats, Wistar; Systole; Tetrahydroisoquinolines; Time Factors; Ventricular Dysfunction, Left | 2001 |
Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Female; Imidazoles; Interleukin-1; Leucine; Lung; Mice; Pancreatitis; Peroxidase; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 2001 |
The role of recombinant human erythropoietin in lipid peroxidation and platelet-activating factor generation in a rat model of necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Erythropoietin; Female; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Platelet Activating Factor; Probability; Rats; Rats, Wistar; Recombinant Proteins; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
Relationship between pancreatitis and lung diseases.
Topics: Acute Disease; Animals; Complement C5a; Disease Models, Animal; Female; Humans; Intercellular Adhesion Molecule-1; Lung Diseases; Mice; Mice, Knockout; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Receptors, CCR1; Receptors, Chemokine; Substance P | 2001 |
Involvement of platelet activation in experimental osteonecrosis in rabbits.
Topics: Animals; Chi-Square Distribution; Disease Models, Animal; Lipopolysaccharides; Osteonecrosis; Platelet Activating Factor; Rabbits; Salmonella enteritidis | 2001 |
Airway hyperresponsiveness in transgenic mice overexpressing platelet activating factor receptor is mediated by an atropine-sensitive pathway.
Topics: Animals; Atropine; Bronchial Diseases; Bronchoconstrictor Agents; Bronchodilator Agents; Disease Models, Animal; Free Radical Scavengers; Methacholine Chloride; Mice; Mice, Transgenic; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Respiratory System; Serotonin; Signal Transduction | 2002 |
Platelet-activating factor drives eotaxin production in an allergic pleurisy in mice.
Topics: Animals; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleura; Pleurisy; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 2002 |
Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipoprotein.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cell Movement; Chemokine CCL2; Chemokines; Disease Models, Animal; Diterpenes; Eosinophils; Ginkgolides; Humans; Inflammation; Lactones; Leukocytes; Lipoproteins, LDL; Mice; Neutrophils; Phospholipids; Platelet Activating Factor; Pleural Effusion; Pleurisy; RNA, Messenger | 2002 |
Suppression of the Arthus reaction by Y-24180, a potent and specific antagonist of platelet-activating factor.
Topics: Animals; Arthus Reaction; Azepines; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Male; Molecular Structure; Ovalbumin; Pancreatitis; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin; Skin Diseases; Triazoles | 1992 |
Induction of experimental anti-phospholipid syndrome associated with SLE following immunization with human monoclonal pathogenic anti-DNA idiotype.
Topics: Animals; Antibodies, Anticardiolipin; Antibodies, Antinuclear; Antiphospholipid Syndrome; Body Weight; Cross Reactions; Disease Models, Animal; Female; Fetal Resorption; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Organ Size; Phospholipids; Placenta; Platelet Activating Factor; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Vaccination | 1992 |
Protective effect of platelet-activating factor antagonist on hepatic energy metabolism following transient hepatic inflow occlusion in rabbits.
Topics: Animals; Disease Models, Animal; Energy Metabolism; Ischemia; Ketone Bodies; Lactates; Liver; Male; Mitochondria, Liver; Platelet Activating Factor; Portal System; Pyridinium Compounds; Rabbits | 1992 |
Light and lithium effects in the rat retina: modification by the PAF antagonist BN 52021.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Image Processing, Computer-Assisted; Lactones; Light; Lithium; Male; Phagosomes; Platelet Activating Factor; Rats; Retina; Retinal Diseases; Rod Cell Outer Segment | 1992 |
[Platelet activating factor (PAF)-induced late asthmatic response in sensitized but not in non-sensitized guinea pigs].
Topics: Airway Resistance; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Guinea Pigs; Male; Platelet Activating Factor | 1992 |
[The physiopathology of acute pancreatitis: the role of platelet-activating factor (PAF)].
Topics: Acute Disease; Animals; Ascitic Fluid; Biological Assay; Disease Models, Animal; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1992 |
Effect of WEB 2086 on myocardial infarct size and regional blood flow in the dog.
Topics: Animals; Azepines; Cardiac Output; Coronary Disease; Disease Models, Animal; Dogs; Myocardial Infarction; Myocardium; Platelet Activating Factor; Regional Blood Flow; Triazoles | 1992 |
WEB 2086 inhibits neutrophil dependent increases in coronary resistance in blood perfused rabbit heart.
Topics: Animals; Azepines; Disease Models, Animal; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Triazoles; Vascular Resistance | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Effects of NZ-107 on bronchoconstriction in guinea pigs.
Topics: Albuterol; Animals; Asthma; Bronchoconstriction; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Histamine; Hydrocortisone; Male; Metyrapone; Platelet Activating Factor; Prednisolone; Pyridazines; Respiration; Time Factors | 1992 |
Endotoxin and hypoxia-induced intestinal necrosis in rats: the role of platelet activating factor.
Topics: Animals; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hypoxia; Intestines; Lipopolysaccharides; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1992 |
Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis.
Topics: Acute Disease; Animals; Chronic Disease; Colitis; Dinoprostone; Disease Models, Animal; Histamine; Interleukin-1; Leukotriene B4; Peroxidase; Platelet Activating Factor; Saguinus | 1991 |
Mechanisms of glomerular injury in experimental immune nephritis. II. Effect of a platelet activating factor receptor antagonist in an autologous nephritis model.
Topics: Albuminuria; Animals; Creatinine; Disease Models, Animal; Kidney Glomerulus; Male; Nephritis; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Lew; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1991 |
Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Eosinophils; Female; Ginkgolides; Immunohistochemistry; Islets of Langerhans; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred BB | 1991 |
A limited role for leukotrienes and platelet-activating factor in food protein induced jejunal smooth muscle contraction in sensitized rats.
Topics: Anaphylaxis; Animals; Dietary Proteins; Disease Models, Animal; Food Hypersensitivity; In Vitro Techniques; Jejunum; Leukotrienes; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats | 1991 |
Protective effects of dazmegrel on the PAF potential of ouabain-induced cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Disease Models, Animal; Drug Synergism; Female; Guinea Pigs; Imidazoles; Lysine; Ouabain; Platelet Activating Factor; Thromboxane-A Synthase | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 2. Effect on antigen-induced dual asthmatic response and infiltration of leukocytes into airways in actively sensitized conscious guinea pigs.
Topics: Animals; Antigens; Asthma; Cromolyn Sodium; Disease Models, Animal; Fenoterol; Guinea Pigs; Leukocytes; Lung; Male; Ovalbumin; Platelet Activating Factor; Respiratory Function Tests; Respiratory System; Thiazoles; Thiazolidines | 1991 |
The interrelation between TNF, IL-6, and PAF secretion induced by LPS in an in vivo and in vitro murine model.
Topics: Animals; Biological Assay; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Interleukin-6; Lipopolysaccharides; Mice; Platelet Activating Factor; Shock, Septic; Tumor Necrosis Factor-alpha | 1991 |
Effect of platelet activating factor on reticuloendothelial system function.
Topics: Animals; Burns; Cecum; Disease Models, Animal; Injections, Intravenous; Intestine, Small; Mononuclear Phagocyte System; Necrosis; Platelet Activating Factor; Rats; Stomach; Technetium Tc 99m Sulfur Colloid | 1991 |
[The effect of interleukin-1 on ocular inflammation in rabbit ocular tissue].
Topics: Animals; Aqueous Humor; Dinoprostone; Disease Models, Animal; Endophthalmitis; Eye Proteins; Indomethacin; Interleukin-1; Phospholipid Ethers; Platelet Activating Factor; Rabbits | 1991 |
Inhibition of cyclic flow variations and reocclusion after thrombolysis in dogs by a novel antagonist of platelet-activating factor.
Topics: Administration, Oral; Animals; Benzodiazepines; Bleeding Time; Blood Coagulation; Blood Flow Velocity; Coronary Thrombosis; Disease Models, Animal; Dogs; Drug Therapy, Combination; Hemodynamics; Partial Thromboplastin Time; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Prothrombin Time; Recurrence; Tissue Plasminogen Activator; Triazolam; Triazoles | 1991 |
Effects of YM264, a novel PAF antagonist, on puromycin aminonucleoside-induced nephropathy in the rat.
Topics: Animals; Azepines; Disease Models, Animal; Glomerulonephritis, Membranous; Hypercholesterolemia; Male; Metabolic Clearance Rate; Methylprednisolone; Piperazines; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Ticlopidine; Triazoles | 1991 |
Allergen-induced bronchospasm in passively sensitized guinea pigs: influence of new substances in comparison to reference compounds.
Topics: Acrylates; Allergens; Animals; Azepines; Benzoates; Bronchial Spasm; Disease Models, Animal; Guinea Pigs; Immunization, Passive; Male; Ovalbumin; Phospholipases A; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles | 1991 |
[Involvement of platelet activating factor (PAF) in ovalbumin antigen-induced late asthmatic response and increase of airway hyperresponsiveness in a guinea pig experimental model of asthma].
Topics: Airway Resistance; Animals; Asthma; Azepines; Disease Models, Animal; Guinea Pigs; Hypersensitivity, Delayed; Male; Ovalbumin; Platelet Activating Factor; Triazoles | 1991 |
Mono-hydroxyeicosatetraenoic acids during porcine endotoxemia. Effect of a platelet-activating factor receptor antagonist.
Topics: Animals; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Disease Models, Animal; Endotoxins; Escherichia coli; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Quinolines; Respiratory Distress Syndrome; Swine | 1990 |
Platelet-activating factor mediates glycerol-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Alprazolam; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Glycerol; Kidney; Kidney Failure, Chronic; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Evidence for platelet-activating factor as a novel mediator in experimental stroke in rabbits.
Topics: Animals; Azepines; Cerebrovascular Disorders; Disease Models, Animal; Platelet Activating Factor; Rabbits; Reference Values; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries; Triazoles | 1990 |
Platelet-activating factor: evidence against a role in hypoxic pulmonary vasoconstriction.
Topics: Animals; Azepines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Male; Platelet Activating Factor; Pulmonary Circulation; Swine; Triazoles; Vascular Resistance; Vasoconstriction | 1990 |
Role of platelet activating factor in the pathogenesis of active and passive models of experimental allergic encephalomyelitis in the rat.
Topics: Animals; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Immunization, Passive; Platelet Activating Factor; Rats | 1990 |
A rabbit model of pulmonary hypertension induced by the synthetic platelet-activating factor acetylglyceryl ether phosphorylcholine.
Topics: Animals; Blood Cell Count; Body Weight; Bronchi; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Extravascular Lung Water; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Platelet Activating Factor; Platelet Aggregation; Pulmonary Alveoli; Pulmonary Artery; Rabbits | 1990 |
[Inhibitory effects of OKY-046.HCl, a selective thromboxane (TX) A2 synthetase inhibitor, on platelet activating factor (PAF)-induced airway hyperresponsiveness in guinea pigs].
Topics: Acrylates; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; In Vitro Techniques; Male; Methacrylates; Platelet Activating Factor; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Computerized optoelectronic induction and registration of arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Computers; Disease Models, Animal; Electric Stimulation; Endothelium, Vascular; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombosis | 1990 |
The effects of PAF antagonists on arrhythmias and platelets during acute myocardial ischaemia and reperfusion.
Topics: Acute Disease; Animals; Blood Gas Analysis; Cardiac Complexes, Premature; Coronary Disease; Disease Models, Animal; Diterpenes; Dogs; Drug Evaluation, Preclinical; Electrocardiography; Ginkgolides; Hemodynamics; Hydrogen-Ion Concentration; Lactones; Myocardial Reperfusion; Oxygen; Platelet Activating Factor; Platelet Count; Quinolinium Compounds; Random Allocation; Tachycardia; Time Factors; Ventricular Fibrillation | 1989 |
Interstitial mononuclear cell infiltrates in experimental nephrosis: effect of PAF antagonist.
Topics: Acetates; Animals; Antibodies, Monoclonal; Disease Models, Animal; Diterpenes; Doxorubicin; Ginkgolides; Immunoenzyme Techniques; In Vitro Techniques; Kidney; Kidney Glomerulus; Lactones; Male; Nephritis, Interstitial; Nephrotic Syndrome; Platelet Activating Factor; Proteinuria; Puromycin; Rats; Rats, Inbred Strains | 1989 |
Modulation of resynthesis of 1-alkyl-2-arachidonyl-glycero-3-phosphocholine and phosphatidylinositols for interception in vivo of free arachidonic acid, lyso-PAF, diacyl-glycerols, and phosphoinositides.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Diglycerides; Disease Models, Animal; Flavonoids; Ginkgo biloba; Hemostatics; Humans; Lysophosphatidylcholines; Pain; Pain Measurement; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor; Swine | 1989 |
Pharmacological demonstration of inflammatory mediators using experimental inflammatory models: rat pleurisy induced by carrageenin and phorbol myristate acetate.
Topics: Animals; Capillary Permeability; Carrageenan; Disease Models, Animal; Epoprostenol; Guinea Pigs; Inflammation; Kinins; Platelet Activating Factor; Pleurisy; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles | 1989 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles | 1989 |
A PAF-acether antagonist (N 48740 RP/Rhône-Poulenc) and laser-induced thrombi in rat mesenteric vessels.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Lasers; Male; Mesenteric Arteries; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridines; Rats; Rats, Inbred Strains; Thiazoles; Thrombosis | 1989 |
Modulation of leucocyte activation in the early phase of the rabbit burn injury.
Topics: Animals; Burns; Calcimycin; Disease Models, Animal; Diterpenes; Free Radicals; Ginkgolides; Lactones; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Rabbits; Superoxides | 1988 |
SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Depression, Chemical; Dinoprostone; Disease Models, Animal; Enterocolitis, Pseudomembranous; Leukotriene B4; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins; Rabbits; Superoxide Dismutase; Thromboxane B2 | 1988 |
Pharmacologic modulation of experimental postischemic hepatic function.
Topics: Animals; Bile; Disease Models, Animal; Drug Evaluation, Preclinical; Hot Temperature; Ibuprofen; Ischemia; Liver; Male; Microscopy, Electron; Perfusion; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase; Transaminases | 1989 |
Role of thromboxane A2, 5-hydroxytryptamine, and platelet activating factor in collagen-induced sudden death in rabbits.
Topics: Animals; Blood Platelets; Collagen; Death, Sudden; Disease Models, Animal; Male; Platelet Activating Factor; Rabbits; Serotonin; Thromboxane A2 | 1987 |
Immune complex induced pancreatitis: effect of BN 52021, a selective antagonist of platelet-activating factor.
Topics: Animals; Capillary Permeability; Disease Models, Animal; Diterpenes; Ginkgolides; Immune Complex Diseases; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1988 |
Experimental eosinophilia and inflammation--the effect of various inflammatory mediators and chemoattractants.
Topics: Acid Phosphatase; Animals; Arylsulfatases; Blood Proteins; Bradykinin; Carrageenan; Cell Movement; Chemotactic Factors; Chemotactic Factors, Eosinophil; Disease Models, Animal; Eosinophil Granule Proteins; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine; Inflammation; Isoenzymes; Male; Neutrophils; Peroxidase; Peroxidases; Platelet Activating Factor; Ribonucleases; Time Factors; Trichinellosis | 1986 |
Platelet-activating factor-induced ischemic bowel necrosis. An investigation of secondary mediators in its pathogenesis.
Topics: Alprostadil; Animals; Blood Pressure; Catechols; Chromones; Diethylcarbamazine; Disease Models, Animal; Hematocrit; Indomethacin; Intestines; Ischemia; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Masoprocol; Methacrylates; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella typhi; Thromboxane-A Synthase; Verapamil | 1986 |
[Test hierarchy for the development of new drug action principles with the action site in phospholipid metabolism for bronchial asthma and pulmonary hypertension].
Topics: Animals; Arachidonic Acids; Asthma; Disease Models, Animal; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Hypertension, Pulmonary; Lipoxygenase Inhibitors; Platelet Activating Factor; Pulmonary Artery; Rabbits | 1988 |
Influence of inhibitors of the eicosanoid metabolism, of antagonists of the eicosanoids and of PAF on mortality assayed in three biochemically characterized shock models.
Topics: Anaphylaxis; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Lipoxygenase Inhibitors; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic | 1988 |
Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis.
Topics: Animals; Colitis; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Trinitrobenzenesulfonic Acid | 1988 |
Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.
Topics: Animals; Blood Pressure; Disease Models, Animal; Diterpenes; Escherichia coli Infections; Ethanol; Ginkgolides; Glyceryl Ethers; Intestine, Small; Lactones; Lipopolysaccharides; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach; Thiazoles | 1987 |
Sequential release of leukotrienes and norepinephrine in rat bowel after platelet-activating factor. A mechanistic study of platelet-activating factor-induced bowel necrosis.
Topics: Animals; Catecholamines; Disease Models, Animal; Guinea Pigs; Intestine, Small; Ischemia; Male; Necrosis; Norepinephrine; Platelet Activating Factor; Rats; SRS-A; Vasoconstriction | 1988 |
Bowel necrosis induced by tumor necrosis factor in rats is mediated by platelet-activating factor.
Topics: Animals; Digestive System; Disease Models, Animal; Ischemia; Lipopolysaccharides; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1988 |
Effect of BN 52021, a platelet activating factor antagonist, on experimental murine contact dermatitis.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Lactones; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Skin | 1988 |
PAF-acether in chronic arthritis.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Disease Models, Animal; Humans; Inflammation; Injections, Intra-Articular; Male; Ovalbumin; Platelet Activating Factor; Rabbits; Synovial Fluid | 1987 |
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Animals; Chromonar; Collagen; Coronary Disease; Coumarins; Disease Models, Animal; Dogs; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Regional Blood Flow; Thromboxane B2 | 1985 |