Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Blood Poisoning

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with Blood Poisoning in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19905 (9.26)18.7374
1990's28 (51.85)18.2507
2000's15 (27.78)29.6817
2010's4 (7.41)24.3611
2020's2 (3.70)2.80

Authors

AuthorsStudies
Gu, X; Jiao, Y; Liu, M; Ma, Z; Qi, M; Shi, X; Xie, X; Zhang, T; Zhou, L1
Bauer, JM; Bernhard, S; Erber, M; Fauler, M; Föhr, KJ; Hoffmann, A; Huber-Lang, M; Hug, S; Knapp, CL; Messerer, DAC; Radermacher, P; Stratmann, AEP; Vidoni, L; Wohlgemuth, L1
Gill, P; Jagdis, A; Jindal, NL; Vadas, P1
da Silva, MC; de Miranda, PE; Estato, V; Miranda, AS; Morandi, V; Pinho, V; Plotkowski, MC; Saliba, AM; Santos, SA; Teixeira, MM; Tibiriça, E; Vianna, A1
Guo, H; Li, B; Liu, LP; Shi, B; Yin, C1
Weyrich, AS; Yost, CC; Zimmerman, GA1
de Lima, CD; de Oliveira, AV; Machado, GB; Plotkowski, MC; Saliba, AM; Suassuna, JH1
Hirasawa, H; Matsuda, K; Nakanishi, K; Oda, S; Shiga, H; Ueno, H1
Bozza, FA; Bozza, M; Bozza, PT; Castro-Faria-Neto, HC; Gomes, RN; Pacheco, P; Weller, PF1
Marshall, JC1
Abraham, E; Balk, R; Coyne, E; Levy, H; Lowry, S; Metzler, M; Opal, S; Pribble, J; Schuster, DP; Slotman, G; Souza, S1
Rabinovici, R1
Bourgeois, M; De Vriese, AS1
Karabina, SA; Ninio, E1
Alves-Filho, JC; Cunha, FQ; Ferreira, SH; Moreno, SE; Rios-Santos, F; Silva, JS; Teixeira, MM1
Miller, CL1
Brunet, F; Dhainaut, JF; Mira, JP1
Fujita, K; Kaido, T; Kasamatsu, T; Kohmoto, M; Tamura, J; Tanaka, J; Yoshida, M1
Ono, S1
Barradas, MA; Jeremy, JY; Mikhailidis, DP; Nystrom, ML1
Bussolino, F1
Connolly, RJ; Dinarello, CA; Dirkes, K; Gelfand, JA; Harris, BH; Schwaitzberg, SD1
de Boer, M; Koenderman, L; Kuijpers, TW; Mascart-Lemone, F; Roos, D; van Zwieten, R; Verhoeven, AJ1
Mochizuki, H; Ono, S; Tamakuma, S1
Ayala, A; Chaudry, IH1
Bernard, GR; Weikert, LF1
Abu-Zidan, FM; Walther, S1
Anderson, MR; Blumer, JL1
Abdullah, F; Mathiak, G; Ovadia, P; Rabinovici, R; Szewczyk, D1
Karzai, W; Reinhart, K1
Buades, J; Camussi, G; Mariano, F; Ronco, C; Tetta, C; Wratten, ML1
Manji, M; Neoptolemos, JP; Wilson, PG1
Fink, MP1
Thijs, A; Thijs, LG1
Gramm, HJ; Karzai, W; Reinhart, K1
Beyer, AJ; Cheung, LY; Shyr, YM; Smalley, DM; Wood, JG1
Damas, P; de Vathaire, F; Dhainaut, JF; Gourlay, ML; Guinot, P; Hemmer, M; Holzapfel, L; Le Tulzo, Y; Mira, JP; Radermacher, P; Schaller, MD; Sollet, JP; Tenaillon, A; Vedrinne, JM; Wolff, M; Zeni, F1
Akizuki, E; Ishihara, K; Liang, J; Matsuda, T; Matsumura, F; Ogawa, M; Ohshiro, H; Okabe, K; Yamada, S; Yamaguchi, Y1
Camussi, G; Cavalli, PL; Donati, D; Guida, G; Mariano, F; Piccoli, G; Tetta, C; Verzetti, G1
Akisü, M; Coker, I; Hüseyinov, A; Kantar, M; Kültürsay, N1
Bakker, J; Curtis, L; Spapen, H; Vincent, JL; Webster, NR1
Connolly, AB; Vernon, DR1
Fischer, JE; James, JH1
Dubois, MJ; Vincent, JL1
Añel, RL; Kumar, A1
McIntyre, TM; Prescott, SM; Stafforini, DM; Zimmerman, GA1
Bone, RC1
Ringer, TV; Zimmerman, JJ1
Inoue, Y; Kohno, S; Miyazaki, T; Yamaguchi, K1
Fernandez-Gallardo, S; Gijon, MA; Lopez Diez, F; Nieto, ML; Sanchez Crespo, M1
Braquet, P; Hosford, D1
Bosia, A; Bussolino, F; Porcellini, MG; Varese, L1
Gomez-Cambronero, J; Hernando, L; Iñarrea, P; Pascual, J; Ponte, MC; Sánchez-Crespo, M1

Reviews

25 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Blood Poisoning

ArticleYear
The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses.
    Biochimie, 2010, Volume: 92, Issue:6

    Topics: Animals; Humans; Inflammation; Platelet Activating Factor; Sepsis; Signal Transduction

2010
Such stuff as dreams are made on: mediator-directed therapy in sepsis.
    Nature reviews. Drug discovery, 2003, Volume: 2, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Clinical Trials as Topic; Endotoxins; Granulocyte Colony-Stimulating Factor; Humans; Interleukin 1 Receptor Antagonist Protein; Nitric Oxide; Platelet Activating Factor; Protein C; Sepsis; Sialoglycoproteins; Thromboplastin; Tumor Necrosis Factor-alpha

2003
Pharmacologic treatment of acute renal failure in sepsis.
    Current opinion in critical care, 2003, Volume: 9, Issue:6

    Topics: Acute Kidney Injury; Anticoagulants; Antineoplastic Agents; Antithrombins; Endothelins; Growth Substances; Humans; Interleukin-8; Lipoproteins; Natriuretic Peptides; Nitric Oxide Synthase; Platelet Activating Factor; Protein C; Sepsis; Steroids; Tumor Necrosis Factor-alpha

2003
Plasma PAF-acetylhydrolase: an unfulfilled promise?
    Biochimica et biophysica acta, 2006, Volume: 1761, Issue:11

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Inflammatory Agents; Asthma; Atherosclerosis; Biomarkers; Disease Models, Animal; Humans; Inflammation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Recombinant Proteins; Sepsis

2006
Infection in massively injured patients.
    Progress in clinical and biological research, 1982, Volume: 108

    Topics: Bacterial Infections; Blood Coagulation Factors; Burns; Complement Activation; Glucocorticoids; Glycoproteins; Humans; Immunity, Cellular; Inflammation; Macrophages; Plasminogen Activators; Platelet Activating Factor; Pyrogens; Sepsis; Wounds and Injuries

1982
Platelet-activating factor antagonists as therapeutic strategy in sepsis.
    Progress in clinical and biological research, 1994, Volume: 388

    Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Humans; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis; Shock, Septic

1994
Eicosanoids and septicaemia.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 50, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Disseminated Intravascular Coagulation; Eicosanoids; Endothelium, Vascular; Endotoxins; Humans; Leukocytes; Platelet Activating Factor; Rats; Sepsis

1994
Platelet activating factor and its role in trauma, shock, and sepsis.
    New horizons (Baltimore, Md.), 1996, Volume: 4, Issue:2

    Topics: Animals; Humans; Platelet Activating Factor; Sepsis; Shock; Wounds and Injuries

1996
Pharmacotherapy of sepsis.
    Clinics in chest medicine, 1996, Volume: 17, Issue:2

    Topics: Acetylcysteine; Antioxidants; Bradykinin; Cyclooxygenase Inhibitors; Humans; Naloxone; Pentoxifylline; Platelet Activating Factor; Sepsis

1996
Advances in the therapy for sepsis in children.
    Pediatric clinics of North America, 1997, Volume: 44, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Child; Child, Preschool; Cytokines; Humans; Immunoglobulins, Intravenous; Immunotherapy; Infant; Infant, Newborn; Platelet Activating Factor; Receptors, Interleukin-1; Sepsis; Severity of Illness Index; Steroids; Terminology as Topic

1997
Platelet-activating factor (PAF) in experimental and clinical sepsis.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:6

    Topics: Animals; Gram-Negative Bacterial Infections; Humans; Platelet Activating Factor; Sepsis

1997
Immune modulation and sepsis.
    International journal of clinical practice, 1997, Volume: 51, Issue:4

    Topics: Adjuvants, Immunologic; Antibodies, Monoclonal; Cytokines; Granulocyte Colony-Stimulating Factor; Humans; Inflammation Mediators; Interleukin-1; Platelet Activating Factor; Recombinant Fusion Proteins; Recombinant Proteins; Sepsis; Tumor Necrosis Factor-alpha

1997
Relevance of platelet-activating factor in inflammation and sepsis: mechanisms and kinetics of removal in extracorporeal treatments.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1997, Volume: 30, Issue:5 Suppl 4

    Topics: Adsorption; Animals; Cell Adhesion; Endothelium, Vascular; Hemofiltration; Humans; Inflammation; Platelet Activating Factor; Sepsis

1997
Acute pancreatitis as a model of sepsis.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl A

    Topics: Acute Disease; Cytokines; Endotoxins; Humans; Multiple Organ Failure; Pancreatitis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sepsis; Systemic Inflammatory Response Syndrome; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

1998
Therapeutic options directed against platelet activating factor, eicosanoids and bradykinin in sepsis.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl A

    Topics: Bradykinin; Cyclooxygenase Inhibitors; Eicosanoids; Humans; Kinins; Lipoxygenase Inhibitors; Platelet Activating Factor; Receptors, Leukotriene; Receptors, Thromboxane; Sepsis

1998
Pathogenesis of renal failure in sepsis.
    Kidney international. Supplement, 1998, Volume: 66

    Topics: Acute Kidney Injury; Adenosine; Endothelin-1; Humans; Interleukins; Leukotrienes; Nitric Oxide; Platelet Activating Factor; Renal Circulation; Sepsis; Tumor Necrosis Factor-alpha

1998
[Current aspects of immunomodulatory therapy initiation for sepsis].
    Deutsche medizinische Wochenschrift (1946), 1998, Jul-31, Volume: 123, Issue:31-32

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Granulocyte Colony-Stimulating Factor; Humans; Immunization, Passive; Interleukin-1; Platelet Activating Factor; Sepsis; Steroids; Tumor Necrosis Factor-alpha

1998
Manipulations of the metabolic response for management of patients with severe surgical illness: review.
    World journal of surgery, 2000, Volume: 24, Issue:6

    Topics: Animals; Growth Substances; Humans; Nutritional Support; Platelet Activating Factor; Sepsis; Shock, Septic; Stress, Physiological; Surgical Procedures, Operative; Tumor Necrosis Factor-alpha; Wounds and Injuries

2000
Are the effects of platelet-activating factor on muscle metabolism of carbohydrates, amino acids and proteins attributable mainly to epinephrine?
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:4

    Topics: Amino Acids; Animals; Carbohydrate Metabolism; Epinephrine; Muscle Proteins; Muscle, Skeletal; Platelet Activating Factor; Rats; Sepsis

2000
Clinically-oriented therapies in sepsis: a review.
    Journal of endotoxin research, 2000, Volume: 6, Issue:6

    Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Clinical Trials as Topic; Endotoxins; Hemofiltration; Humans; Interleukin-1; Platelet Activating Factor; Sepsis; Steroids; Tumor Necrosis Factor-alpha

2000
Experimental and emerging therapies for sepsis and septic shock.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:8

    Topics: Animals; Caspase Inhibitors; Complement System Proteins; Enzyme Inhibitors; Fibrinolytic Agents; Humans; Nitric Oxide Synthase; Platelet Activating Factor; Sepsis; Shock, Septic; Steroids

2001
The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis.
    Critical care medicine, 2002, Volume: 30, Issue:5 Suppl

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Cytokines; Humans; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis; Signal Transduction; Thrombosis

2002
Phospholipids and their inhibitors: a critical evaluation of their role in the treatment of sepsis.
    Critical care medicine, 1992, Volume: 20, Issue:6

    Topics: Animals; Cyclooxygenase Inhibitors; Humans; Leukotriene Antagonists; Phospholipids; Platelet Activating Factor; Prostaglandins, Synthetic; Sepsis; Shock, Septic; Thromboxane A2

1992
Inflammatory host responses in sepsis.
    Critical care clinics, 1992, Volume: 8, Issue:1

    Topics: Biological Factors; Cell Adhesion Molecules; Child; Complement Activation; Eicosanoids; Endorphins; Humans; Interleukins; Leukocytes; Leukotrienes; Platelet Activating Factor; Sepsis; Tumor Necrosis Factor-alpha

1992
The potential role of platelet-activating factor (PAF) in shock, sepsis and adult respiratory distress syndrome (ARDS).
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Brain; Burns; Digestive System; Endotoxins; Humans; Kidney; Lung; Platelet Activating Factor; Respiratory Distress Syndrome; Sepsis; Shock, Septic; Shock, Traumatic

1989

Trials

4 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Blood Poisoning

ArticleYear
Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial.
    Critical care medicine, 2003, Volume: 31, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Logistic Models; Male; Middle Aged; Phospholipases A; Platelet Activating Factor; Prevalence; Proportional Hazards Models; Prospective Studies; Recombinant Proteins; Respiratory Distress Syndrome; Sepsis; Survival Analysis; United States

2003
A clinical study on the significance of platelet-activating factor in the pathophysiology of septic disseminated intravascular coagulation in surgery.
    American journal of surgery, 1996, Volume: 171, Issue:4

    Topics: Carcinoma, Hepatocellular; Data Interpretation, Statistical; Disseminated Intravascular Coagulation; Endotoxins; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Sepsis; Surgical Procedures, Operative

1996
Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group.
    Critical care medicine, 1998, Volume: 26, Issue:12

    Topics: Adult; Aged; Analysis of Variance; APACHE; Diterpenes; Double-Blind Method; Free Radical Scavengers; Ginkgolides; Gram-Negative Bacterial Infections; Humans; Lactones; Middle Aged; Platelet Activating Factor; Prospective Studies; Sepsis; Survival Analysis

1998
Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis.
    Critical care medicine, 2000, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; APACHE; Cytokines; Double-Blind Method; Europe; Female; Hemodynamics; Humans; Immunotherapy; Infusions, Intravenous; Lactic Acid; Leucine; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Function Tests; Sepsis; Survival Analysis

2000

Other Studies

25 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and Blood Poisoning

ArticleYear
Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis.
    Journal of biomedical science, 2023, Aug-02, Volume: 30, Issue:1

    Topics: Animals; Dinoprostone; Extracellular Traps; Immunoglobulin Class Switching; Lung Injury; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Platelet Activating Factor; Sepsis

2023
Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Endotoxemia; Female; Humans; Hydrogen-Ion Concentration; Inflammation; Male; Membrane Potentials; NADPH Oxidase 2; Neutrophil Activation; Platelet Activating Factor; Sepsis; Swine

2021
Platelets in the immune response: Revisiting platelet-activating factor in anaphylaxis.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anaphylaxis; Asthma; Blood Platelets; Eosinophils; Gene Expression Regulation; Humans; Mast Cells; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Sepsis; Signal Transduction

2015
Contribution of the platelet activating factor signaling pathway to cerebral microcirculatory dysfunction during experimental sepsis by ExoU producing Pseudomonas aeruginosa.
    Pathogens and disease, 2015, Volume: 73, Issue:7

    Topics: Animals; Bacterial Proteins; Brain; Cell Adhesion; Cytokines; Female; Intravital Microscopy; Leukocytes; Mice; Microcirculation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pseudomonas aeruginosa; Pseudomonas Infections; Receptors, G-Protein-Coupled; Sepsis; Signal Transduction

2015
[Influence of intensive insulin therapy on the intestinal microcirculatory dysfunction in rats with sepsis].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2009, Volume: 21, Issue:8

    Topics: Animals; Disease Models, Animal; Epoprostenol; Insulin; Intestinal Mucosa; Intestines; Male; Microcirculation; Platelet Activating Factor; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis; Thromboxane A2

2009
Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis.
    Respiratory research, 2011, Aug-05, Volume: 12

    Topics: Animals; Bacterial Proteins; Blood Coagulation; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Disease Models, Animal; Epithelial Cells; Female; Fibrin; Humans; Immunohistochemistry; Macrophages; Mice; Mutation; Plasminogen Activator Inhibitor 1; Platelet Activating Factor; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Alveoli; Respiratory Mucosa; RNA, Messenger; Sepsis; Time Factors; Up-Regulation

2011
Coagulation/fibrinolysis abnormality and vascular endothelial damage in the pathogenesis of thrombocytopenic multiple organ failure.
    Critical care medicine, 2002, Volume: 30, Issue:10

    Topics: Adult; Aged; Blood Coagulation; Endothelium, Vascular; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Interleukin-6; Leukocyte Elastase; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Count; Retrospective Studies; Sepsis; Thrombocytopenia; Thrombomodulin

2002
Lipopolysaccharide-induced leukocyte lipid body formation in vivo: innate immunity elicited intracellular Loci involved in eicosanoid metabolism.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Dec-01, Volume: 169, Issue:11

    Topics: Adult; Animals; Arachidonate 5-Lipoxygenase; Case-Control Studies; Cyclooxygenase 2; Eicosanoids; Female; Humans; Inclusion Bodies; Inflammation Mediators; Isoenzymes; Leukocytes; Lipid Metabolism; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Middle Aged; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sepsis; Shock, Septic; Signal Transduction; Tumor Necrosis Factor-alpha

2002
Platelet activating factor inhibition in sepsis: the end?
    Critical care medicine, 2003, Volume: 31, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Endpoint Determination; Humans; Phospholipases A; Platelet Activating Factor; Research Design; Respiratory Distress Syndrome; Sepsis

2003
Signaling via platelet-activating factor receptors accounts for the impairment of neutrophil migration in polymicrobial sepsis.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Jul-15, Volume: 177, Issue:2

    Topics: Animals; Cecum; Cell Adhesion; Cell Movement; Chemokines; Immunity, Innate; Ligation; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophil Infiltration; Platelet Activating Factor; Platelet Membrane Glycoproteins; Punctures; Receptors, G-Protein-Coupled; Sepsis; Signal Transduction

2006
Significance of altered fluidity of plasma membranes of the liver and kidney in rats with sepsis.
    The Journal of surgical research, 1995, Volume: 58, Issue:2

    Topics: Animals; Fluorescence Polarization; Kidney; Lipopolysaccharides; Liver; Male; Membrane Fluidity; Multiple Organ Failure; Platelet Activating Factor; Rats; Rats, Wistar; Sepsis

1995
[Clinical and experimental studies of septic DIC in surgical patients, in terms of its characteristic features and pathogenesis].
    Nihon Geka Gakkai zasshi, 1994, Volume: 95, Issue:12

    Topics: Animals; Disseminated Intravascular Coagulation; Endotoxins; Fibrinolysis; Humans; Kidney Cortex; Plasminogen Activators; Platelet Activating Factor; Platelet Count; Postoperative Complications; Rabbits; Sepsis

1994
Platelet and plasma platelet-activating factor in sepsis and myocardial infection.
    Journal of lipid mediators and cell signalling, 1994, Volume: 10, Issue:1-2

    Topics: Humans; Platelet Activating Factor; Sepsis

1994
Platelet activating factor-antagonist improves survival in experimental staphylococcal septicemia.
    Journal of pediatric surgery, 1994, Volume: 29, Issue:8

    Topics: Animals; Hemodynamics; Leukocyte Count; Organophosphorus Compounds; Platelet Activating Factor; Platelet Count; Rabbits; Sepsis; Staphylococcal Infections; Staphylococcus epidermidis; Thiazoles

1994
A novel syndrome of severe neutrophil dysfunction: unresponsiveness confined to chemotaxin-induced functions.
    Blood, 1993, May-15, Volume: 81, Issue:10

    Topics: Actins; Antigens, CD; Calcimycin; Calcium; CD18 Antigens; CD4 Antigens; CD8 Antigens; Cell Adhesion; Cell Aggregation; Chemotaxis, Leukocyte; Cytochalasin B; Endothelium, Vascular; Female; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; Infant, Newborn; Kinetics; Leukocyte Count; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Reference Values; Sepsis; Syndrome; T-Lymphocyte Subsets

1993
Platelet activating factor antagonism improves cardiovascular function in non-hypotensive sepsis in pigs.
    The European journal of surgery = Acta chirurgica, 1996, Volume: 162, Issue:6

    Topics: Animals; Blood Pressure; Cardiac Output; Endotoxemia; Escherichia coli Infections; Heart Rate; Hemodynamics; Leucine; Platelet Activating Factor; Sepsis; Stroke Volume; Swine

1996
Clinical studies of IL-11, new platelet growth factor, presented.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:2

    Topics: Animals; Breast Neoplasms; Clinical Trials as Topic; Hematopoiesis; Humans; Interleukin-11; Neoplasms; Platelet Activating Factor; Recombinant Proteins; Sepsis; Thrombocytopenia

1997
PAF and CD18 mediate neutrophil infiltration in upper gastrointestinal tract during intra-abdominal sepsis.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Abdomen; Animals; Antibodies, Monoclonal; Azepines; Blood Pressure; CD18 Antigens; Cecum; Hematocrit; Intercellular Adhesion Molecule-1; Intestines; Leukocyte Count; Male; Neutrophils; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sepsis; Triazoles

1998
Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats.
    Pancreas, 1999, Volume: 18, Issue:4

    Topics: Animals; Ceruletide; Chemokines, CXC; Chemotactic Factors; Growth Inhibitors; Growth Substances; Hemorrhage; Intercellular Signaling Peptides and Proteins; Isoquinolines; Kinetics; Lipopolysaccharides; Lung; Lung Diseases; Macrophages, Alveolar; Male; Pancreatitis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Tetrahydroisoquinolines

1999
Production of platelet-activating factor in patients with sepsis-associated acute renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Animals; Female; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Male; Middle Aged; Platelet Activating Factor; Sepsis; Tumor Necrosis Factor-alpha

1999
Platelet-activating factor concentrations in healthy and septic neonates.
    European journal of pediatrics, 1999, Volume: 158, Issue:9

    Topics: Humans; Infant, Newborn; Infant, Premature; Platelet Activating Factor; Reference Values; Sepsis

1999
Effect of a platelet activating factor antagonist and antithrombin III on septicemia and endotoxemia in rats.
    The Tohoku journal of experimental medicine, 1991, Volume: 163, Issue:3

    Topics: Animals; Antithrombin III; Disseminated Intravascular Coagulation; Endotoxins; Kidney; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Sepsis; Toxemia

1991
Occupancy of platelet receptors for platelet-activating factor in patients with septicemia.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:5

    Topics: Adult; Aged; Blood Platelets; Female; Humans; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Count; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis

1989
Intravascular release of platelet activating factor in children with sepsis.
    Thrombosis research, 1987, Dec-01, Volume: 48, Issue:5

    Topics: Child; Child, Preschool; Female; Humans; Male; Platelet Activating Factor; Sepsis

1987
Synthesis of PAF-acether and blood volume changes in gram-negative sepsis.
    Immunopharmacology, 1985, Volume: 9, Issue:1

    Topics: Animals; Bacterial Infections; Blood Volume; Capillary Permeability; Chromatography, High Pressure Liquid; Escherichia coli Infections; Platelet Activating Factor; Rats; Rats, Inbred Strains; Sepsis; Spleen

1985