1-deoxynojirimycin has been researched along with Dengue in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alonzi, DS; Brun, J; Miller, JL; Perera, N; Tyrrell, BE; Zitzmann, N | 1 |
| Callahan, M; Duchars, M; Evans DeWald, L; Kaufman, B; Khaliq, M; Lin, G; Lowe, P; Ramstedt, U; Sampath, A; Smith, M; Spurgers, K; Treston, AM; Warfield, KL | 1 |
| Block, TM; Chang, J; Cuconati, A; Du, Y; Gill, T; Guo, F; Guo, JT; Wang, L; Xu, X; Ye, H | 1 |
| Block, TM; Chang, J; Cuconati, A; Du, Y; Gill, T; Guo, JT; Qu, X; Wang, L; Xu, X; Ye, H; Yu, W; Zhao, K | 1 |
| Bapat, M; Beatty, PR; Dwek, R; Harris, E; Lachica, R; Miller, JL; Sayce, AC; Williams, JP; Zitzmann, N | 1 |
| Flamand, M; Liu, W; Schul, W; Vasudevan, SG; Xu, HY | 1 |
| Courageot, MP; Desprès, P; Deubel, V; Dos Santos, CD; Frenkiel, MP | 1 |
| Dwek, RA; Lee, CJ; Liao, CL; Lin, YL; Wu, SF; Zitzmann, N | 1 |
1 trial(s) available for 1-deoxynojirimycin and Dengue
| Article | Year |
|---|---|
Randomized single oral dose phase 1 study of safety, tolerability, and pharmacokinetics of Iminosugar UV-4 Hydrochloride (UV-4B) in healthy subjects.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Antiviral Agents; Area Under Curve; Dengue; Dose-Response Relationship, Drug; Double-Blind Method; Healthy Volunteers; Humans | 2022 |
7 other study(ies) available for 1-deoxynojirimycin and Dengue
| Article | Year |
|---|---|
Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells.
Topics: 1-Deoxynojirimycin; Antiviral Agents; Dendritic Cells; Dengue; Dengue Virus; Endoplasmic Reticulum; Humans; Macrophages | 2022 |
N-Alkyldeoxynojirimycin derivatives with novel terminal tertiary amide substitution for treatment of bovine viral diarrhea virus (BVDV), Dengue, and Tacaribe virus infections.
Topics: 1-Deoxynojirimycin; Amides; Animals; Antiviral Agents; Cell Line; Cell Survival; Cricetinae; Defective Viruses; Dengue; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Glucosamine; Humans; Molecular Structure; Structure-Activity Relationship | 2013 |
Design, synthesis, and biological evaluation of N-alkylated deoxynojirimycin (DNJ) derivatives for the treatment of dengue virus infection.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Antiviral Agents; Biological Availability; Cattle; Cell Line; Cricetinae; Dengue; Dengue Virus; Diarrhea Viruses, Bovine Viral; Glycoside Hydrolase Inhibitors; Humans; Male; Microbial Sensitivity Tests; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Viral Envelope Proteins; Virus Replication | 2012 |
Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Survival; Dengue; Dengue Virus; Drug Carriers; Drug Delivery Systems; Gene Dosage; Humans; Imino Sugars; In Vitro Techniques; Liposomes; Macrophages; Mice; Real-Time Polymerase Chain Reaction; RNA, Viral | 2012 |
A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Dengue; Disease Models, Animal; Dose-Response Relationship, Drug; Indolizines; Mice; Ribavirin; Time Factors; Tubercidin; Viremia; Virus Replication | 2007 |
Alpha-glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Amino Acid Sequence; Animals; Dengue; Dengue Virus; Endoplasmic Reticulum; Enzyme Inhibitors; Indolizines; Mice; Molecular Sequence Data; Protein Processing, Post-Translational; Viral Structural Proteins; Virion; Virus Replication | 2000 |
Antiviral effects of an iminosugar derivative on flavivirus infections.
Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Cell Line; Cricetinae; Dengue; Dengue Virus; Encephalitis Virus, Japanese; Encephalitis, Japanese; Female; Glycoside Hydrolase Inhibitors; Mice; Mice, Inbred ICR | 2002 |