1-deoxynojirimycin has been researched along with Cystic Fibrosis in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| D'Alonzo, D; Dechecchi, MC; Esposito, A; Fenza, M; Gregorio, E; Guaragna, A; Lippi, G; Tamanini, A | 1 |
| Haÿ, E; Jacquot, JP; Le Henaff, C; Marie, PJ; Marty, C; Tabary, O; Velard, F | 1 |
| Aureli, M; Bassi, R; Bezzerri, V; Cabrini, G; Cantù, C; Cavazzini, A; Cheng, SH; Dechecchi, MC; Gambari, R; Giri, MG; Lampronti, I; Loberto, N; Lovato, V; Marchetti, N; Munari, S; Sonnino, S; Tebon, M | 1 |
| Becq, F; Bezzerri, V; Borgatti, M; Cabrini, G; Dechecchi, MC; Gambari, R; Mancini, I; Nicolis, E; Norez, C; Ribeiro, CM; Rizzotti, P | 1 |
| Antigny, F; Becq, F; Noel, S; Norez, C; Vandebrouck, C | 1 |
| Leal, T; Lebacq, J; Lebecque, P; Leonard, A; Lubamba, B; Vanbever, R; Wallemacq, P | 1 |
| Dingemanse, J; Leal, T; Lebecque, P; Leonard, A | 2 |
| Glenn, LL; Jenkins, BA | 1 |
| Becq, F; Bijvelds, M; DeJonge, H; Jorna, H; Melin, P; Noel, S; Norez, C; Wilke, M | 1 |
| Antigny, F; Becq, F; Norez, C; Vandebrouck, C | 1 |
| Becq, F; Bot, AG; De Jonge, HR; Noël, S; Wilke, M | 1 |
1 review(s) available for 1-deoxynojirimycin and Cystic Fibrosis
| Article | Year |
|---|---|
Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis.
Topics: 1-Deoxynojirimycin; Anti-Inflammatory Agents; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Glycoside Hydrolases; Glycosyltransferases; Heterocyclic Compounds, 1-Ring; Humans; Imino Pyranoses; Inflammation; Molecular Structure; Mutation; Sequence Deletion; Tartrates | 2020 |
1 trial(s) available for 1-deoxynojirimycin and Cystic Fibrosis
| Article | Year |
|---|---|
A randomized placebo-controlled trial of miglustat in cystic fibrosis based on nasal potential difference.
Topics: 1-Deoxynojirimycin; Administration, Oral; Adolescent; Adult; Child; Cross-Over Studies; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Follow-Up Studies; Glycoside Hydrolase Inhibitors; Humans; Male; Nasal Mucosa; Sodium Chloride; Treatment Outcome; Young Adult | 2012 |
10 other study(ies) available for 1-deoxynojirimycin and Cystic Fibrosis
| Article | Year |
|---|---|
Enhanced F508del-CFTR channel activity ameliorates bone pathology in murine cystic fibrosis.
Topics: 1-Deoxynojirimycin; Animals; Bone and Bones; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Enzyme Inhibitors; Male; Mice, Inbred CFTR; Mutation; Osteoblasts | 2014 |
GBA2-encoded β-glucosidase activity is involved in the inflammatory response to Pseudomonas aeruginosa.
Topics: 1-Deoxynojirimycin; beta-Glucosidase; Bronchi; Cystic Fibrosis; Epithelial Cells; Glucosylceramidase; Glycoside Hydrolase Inhibitors; Humans; Inflammation; Pseudomonas aeruginosa; Pseudomonas Infections | 2014 |
Anti-inflammatory effect of miglustat in bronchial epithelial cells.
Topics: 1-Deoxynojirimycin; Bronchi; Cell Culture Techniques; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Epithelial Cells; Humans; Inflammation Mediators; Protein Transport; Respiratory Mucosa | 2008 |
A cystic fibrosis respiratory epithelial cell chronically treated by miglustat acquires a non-cystic fibrosis-like phenotype.
Topics: 1-Deoxynojirimycin; Animals; Calcium; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Epithelial Cells; Epithelial Sodium Channels; Homeostasis; Humans; Mice; Patch-Clamp Techniques; Phenotype; Respiratory Mucosa | 2009 |
Airway delivery of low-dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice.
Topics: 1-Deoxynojirimycin; Administration, Intranasal; Animals; Chloride Channels; Cystic Fibrosis; Enzyme Inhibitors; Mice; Mice, Knockout; Sodium Channels | 2009 |
Miglustat effects on the basal nasal potential differences in cystic fibrosis.
Topics: 1-Deoxynojirimycin; Cystic Fibrosis; Female; Humans; Male; Nasal Mucosa | 2013 |
Miglustat effects on the basal nasal potential differences in cystic fibrosis.
Topics: 1-Deoxynojirimycin; Cystic Fibrosis; Female; Humans; Male; Nasal Mucosa | 2013 |
Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat.
Topics: 1-Deoxynojirimycin; Animals; Calnexin; Chlorocebus aethiops; COS Cells; Cricetinae; Cricetulus; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Glycoside Hydrolase Inhibitors; Humans; In Vitro Techniques; Intestinal Mucosa; Mice; Mice, Inbred CFTR; Mice, Knockout; Protein Binding; Protein Processing, Post-Translational; Protein Transport | 2006 |
Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR.
Topics: 1-Deoxynojirimycin; Adenosine Triphosphate; Benzoates; Boron Compounds; Calcium Signaling; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Epithelial Cells; Histamine; Humans; Inositol 1,4,5-Trisphosphate Receptors; Nocodazole; Protein Transport; Respiratory Mucosa; Sequence Deletion; Temperature; Thiazolidines | 2008 |
Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells.
Topics: 1-Deoxynojirimycin; Amiloride; Animals; Cell Line; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Mice; Mice, Knockout; Nasal Mucosa; Sodium; Sodium Channel Blockers | 2008 |