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1-deoxynojirimycin and Body Weight

1-deoxynojirimycin has been researched along with Body Weight in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's6 (25.00)18.2507
2000's7 (29.17)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eitsuka, T; Ikeda, R; Ito, J; Kimura, T; Miyazawa, T; Nakagawa, K; Parida, IS; Takasu, S; Yamagishi, K1
Chung, JH; Do, HJ; Hwang, JW; Kim, OY; Lee, JY; Shin, MJ1
Barnard, DL; Callahan, MV; Day, CW; Enterlein, SG; Khaliq, M; Ramstedt, U; Sampath, A; Smee, DF; Warfield, KL1
Grittner, U; Holzmann, C; Rolfs, A; Schlegel, V; Thieme, M; Witt, M; Wree, A1
Baek, RC; Bronson, RT; Butters, TD; Denny, CA; Heinecke, KA; Kim, YP; Loh, KS; Platt, FM; Seyfried, TN1
Aerts, JM; Bijl, N; Bijland, S; Groen, AK; Houben-Weerts, JH; Houten, SM; Langeveld, M; Ottenhoff, R; Romijn, JA; van den Berg, SA; van Dijk, KW; van Roomen, CP; Voshol, PJ1
Bhatia, G; Chaturvedi, U; Saxena, JK; Shrivastava, A; Singh, SV1
D'Azzo, A; El-Abbadi, MM; Hauser, EC; Kasperzyk, JL; Platt, FM; Seyfried, TN1
Aerts, JM; Boon, L; Bullens, D; Ceuppens, JL; Geboes, K; Kasran, A; Maerten, P; Rutgeerts, P; Shen, C; Van Assche, G1
Andersson, U; Borja, MC; Butters, TD; Dwek, RA; Jeyakumar, M; Platt, FM; Smith, D1
Fehmann, HC2
Barnett, NL; Kolodny, EH; Pastores, GM1
DeBouno, JF; Michaelis, OE; Tulp, OL1
Butters, TD; Dwek, RA; Platt, FM; Reinkensmeier, G1
Chiasson, JL; Rabasa-Lhoret, R1
Dolphin, PJ; Graham, SE; Russell, JC1
El-Abbadi, M; Manfredi, MG; Mukherjee, P; Platt, FM; Ranes, MK; Seyfried, TN1
Holman, RR; Steemson, J; Turner, RC1
Atsumi, S; Iinuma, H; Nosaka, C; Umezawa, K1
Creutzfeldt, W; Fehmann, HC; Fölsch, UR; Göke, B; Siegel, EG1
Bezerra, J; Bustamante, S; Flores, C; Goda, T; Koldovský, O; Lee, SM1
Gerard, J; Hillebrand, I; Lefèbvre, PJ1
Madar, Z; Olefsky, J1

Reviews

1 review(s) available for 1-deoxynojirimycin and Body Weight

ArticleYear
Potential of alpha-glucosidase inhibitors in elderly patients with diabetes mellitus and impaired glucose tolerance.
    Drugs & aging, 1998, Volume: 13, Issue:2

    Topics: 1-Deoxynojirimycin; Acarbose; Aged; Body Weight; Cognition; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucosamine; Glucose Intolerance; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Trisaccharides

1998

Trials

3 trial(s) available for 1-deoxynojirimycin and Body Weight

ArticleYear
An open-label, noncomparative study of miglustat in type I Gaucher disease: efficacy and tolerability over 24 months of treatment.
    Clinical therapeutics, 2005, Volume: 27, Issue:8

    Topics: 1-Deoxynojirimycin; Adult; Blood; Body Weight; Drug Tolerance; Enzyme Inhibitors; Female; Gaucher Disease; Humans; Liver; Male; Middle Aged; Spleen; Treatment Outcome

2005
Post-prandial glycaemic reduction by an alpha-glucosidase inhibitor in type 2 diabetic patients with therapeutically attained basal normoglycaemia.
    Diabetes research (Edinburgh, Scotland), 1991, Volume: 18, Issue:4

    Topics: 1-Deoxynojirimycin; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diet, Diabetic; Eating; Female; Fructosamine; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Hexosamines; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin, Long-Acting; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Reference Values; Time Factors; Triglycerides

1991
Assessment of the clinical efficacy and tolerance of two new alpha-glucosidase inhibitors in insulin-treated diabetics.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:9

    Topics: 1-Deoxynojirimycin; Adult; Blood Glucose; Body Weight; Diabetes Mellitus; Drug Tolerance; Fatty Acids, Nonesterified; Female; Glucosamine; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Insulin; Male; Middle Aged

1987

Other Studies

20 other study(ies) available for 1-deoxynojirimycin and Body Weight

ArticleYear
Physiological Effects and Organ Distribution of Bacillus amyloliquefaciens AS385 Culture Broth Powder Containing 1-Deoxynojirimycin in C57BL/6J Mice.
    Journal of nutritional science and vitaminology, 2019, Volume: 65, Issue:2

    Topics: 1-Deoxynojirimycin; Animals; Bacillus amyloliquefaciens; Blood Glucose; Body Weight; Culture Media; Insulin; Male; Mice; Mice, Inbred C57BL; Powders; Tissue Distribution

2019
1-deoxynojirimycin isolated from Bacillus subtilis improves hepatic lipid metabolism and mitochondrial function in high-fat-fed mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 75

    Topics: 1-Deoxynojirimycin; Acetyl-CoA Carboxylase; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Bacillus subtilis; Body Weight; CCAAT-Enhancer-Binding Proteins; CD36 Antigens; Diet, High-Fat; Dietary Supplements; Energy Intake; Fatty Acid Synthases; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Obesity; Organ Size; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Transcription Factors

2015
The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice.
    Viruses, 2016, Mar-07, Volume: 8, Issue:3

    Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Body Weight; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Humans; Influenza A virus; Influenza B virus; Mice; Orthomyxoviridae Infections; Survival Analysis; Treatment Outcome

2016
Pharmacologic Treatment Assigned for Niemann Pick Type C1 Disease Partly Changes Behavioral Traits in Wild-Type Mice.
    International journal of molecular sciences, 2016, Nov-09, Volume: 17, Issue:11

    Topics: 1-Deoxynojirimycin; Animals; Behavior, Animal; Body Weight; Brain; Cognition; Cyclodextrins; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Hypolipidemic Agents; Male; Maze Learning; Mice; Mice, Inbred BALB C; Niemann-Pick Disease, Type C; Organ Size; Pregnanolone

2016
Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.
    Journal of neurochemistry, 2010, Volume: 113, Issue:6

    Topics: 1-Deoxynojirimycin; 3-Hydroxybutyric Acid; Analysis of Variance; Animals; beta-N-Acetylhexosaminidases; Blood Glucose; Body Weight; Brain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diet, Ketogenic; Eating; G(M2) Ganglioside; Lipid Metabolism; Mice; Mice, Knockout; Myelin Sheath; Purkinje Cells; Sandhoff Disease

2010
Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and increasing fat oxidation.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:1

    Topics: 1-Deoxynojirimycin; Adamantane; Adipose Tissue; Animals; Body Weight; Carbohydrate Metabolism; Carnitine O-Palmitoyltransferase; Eating; Ghrelin; Glucose; Imino Sugars; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Oxidation-Reduction; Peptide YY; Triglycerides; Up-Regulation; Weight Gain

2012
Lipid lowering and antioxidant effect of miglitol in triton treated hyperlipidemic and high fat diet induced obese rats.
    Lipids, 2013, Volume: 48, Issue:6

    Topics: 1-Deoxynojirimycin; 3T3-L1 Cells; Adipogenesis; Animals; Antioxidants; Body Weight; Diet, High-Fat; Eating; Hyperlipidemias; Hypoglycemic Agents; Lipids; Liver; Male; Mice; Obesity; Polyethylene Glycols; Rats

2013
N-butyldeoxygalactonojirimycin reduces neonatal brain ganglioside content in a mouse model of GM1 gangliosidosis.
    Journal of neurochemistry, 2004, Volume: 89, Issue:3

    Topics: 1-Deoxynojirimycin; Animals; Animals, Newborn; Body Weight; Brain; Brain Chemistry; Chromatography, Thin Layer; Disease Models, Animal; Fetal Viability; Gangliosides; Gangliosidosis, GM1; Lipid Metabolism; Lipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Treatment Outcome

2004
Inhibition of glycolipid biosynthesis by N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin protects against the inflammatory response in hapten-induced colitis.
    International immunopharmacology, 2004, Volume: 4, Issue:7

    Topics: 1-Deoxynojirimycin; Adamantane; Animals; Anti-Inflammatory Agents; Antibodies; Body Weight; Colitis; Colon; Disease Models, Animal; Enzyme Inhibitors; Glycolipids; Haptens; Immunoglobulin G; Immunosuppressive Agents; Interferon-gamma; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Oxazolone; Peroxidase; Trinitrobenzenesulfonic Acid

2004
Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.
    Neurobiology of disease, 2004, Volume: 16, Issue:3

    Topics: 1-Deoxynojirimycin; Animals; Behavior, Animal; beta-N-Acetylhexosaminidases; Body Weight; Brain; Disease Models, Animal; Female; Gangliosides; Life Expectancy; Liver; Male; Mice; Mice, Mutant Strains; Sandhoff Disease

2004
[The alpha-glucosidase inhibitor miglitol for the treatment of type 2 diabetes mellitus in the doctor's office].
    Fortschritte der Medizin. Originalien, 2001, Jul-19, Volume: 119 Suppl 2

    Topics: 1-Deoxynojirimycin; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Female; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses; Male; Middle Aged; Safety; Time Factors; Triglycerides

2001
The effects of the intestinal glucosidase inhibitory BAY M 1099 (miglitol) on glycemic status of obese-diabetic rats.
    General pharmacology, 1993, Volume: 24, Issue:2

    Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Eating; Glucosamine; Glycoside Hydrolase Inhibitors; Imino Pyranoses; Male; Obesity; Rats; Rats, Inbred SHR

1993
Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin.
    The Journal of biological chemistry, 1997, Aug-01, Volume: 272, Issue:31

    Topics: 1-Deoxynojirimycin; Animals; Body Weight; Cholera Toxin; Enzyme Inhibitors; Female; Glucosyltransferases; Glycosphingolipids; Immunophenotyping; Liver; Lymphoid Tissue; Mice; Mice, Inbred C57BL

1997
Glucose tolerance and insulin resistance in the JCR:LA-corpulent rat: effect of miglitol (Bay m1099).
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:6

    Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Eating; Enzyme Inhibitors; Glucosamine; Glucose Tolerance Test; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Imino Pyranoses; Insulin; Insulin Resistance; Lipids; Male; Obesity; Postprandial Period; Rats

1999
N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours.
    British journal of cancer, 2001, Apr-20, Volume: 84, Issue:8

    Topics: 1-Deoxynojirimycin; Animals; Body Weight; Brain; Brain Neoplasms; Cell Count; Cell Division; Gangliosides; Intestines; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Time Factors; Tissue Distribution; Tumor Cells, Cultured

2001
[Alpha-glucosidase inhibitor in type 2 diabetic patients. Metabolism and body weight are favorably modified].
    MMW Fortschritte der Medizin, 2001, Apr-26, Volume: 143, Issue:17

    Topics: 1-Deoxynojirimycin; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Energy Metabolism; Glucosamine; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Imino Pyranoses

2001
Biological activities of cyclophellitol.
    The Journal of antibiotics, 1990, Volume: 43, Issue:12

    Topics: 1-Deoxynojirimycin; Animals; Anti-Bacterial Agents; beta-Glucosidase; Binding, Competitive; Body Weight; Cell Line; Cyclohexanols; Female; Glucosamine; Glucosylceramidase; Indolizines; Mice; Microsomes; Tumor Cells, Cultured

1990
Influence of an absorbable alpha-glucosidase inhibitor (Bay o 1248) on the endocrine and exocrine pancreas of the rat.
    Zeitschrift fur Gastroenterologie, 1986, Volume: 24, Issue:12

    Topics: 1-Deoxynojirimycin; Amylases; Animals; Body Weight; Glucosamine; Glycoside Hydrolase Inhibitors; Insulin; Islets of Langerhans; Male; Pancreas; Rats; Rats, Inbred Strains; Trypsin

1986
Chronic effects of an alpha-glucosidase inhibitor (Bay o 1248) on intestinal disaccharidase activity in normal and diabetic mice.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; beta-Galactosidase; Body Weight; Diabetes Mellitus, Experimental; Disaccharidases; Eating; Glucosamine; Glycoside Hydrolase Inhibitors; Intestine, Small; Mice; Mice, Inbred C57BL; Sucrase

1987
Effect of the alpha-glucosidase inhibitor Bay-O-1248 on the metabolic response of nondiabetic and diabetic rats to a high-carbohydrate diet.
    The American journal of clinical nutrition, 1986, Volume: 44, Issue:2

    Topics: 1-Deoxynojirimycin; Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Glucosamine; Glycosuria; Male; Rats; Rats, Inbred Strains; Triglycerides

1986