Page last updated: 2024-10-16

1-butanol and Pregnancy

1-butanol has been researched along with Pregnancy in 25 studies

1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.
butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" The data demonstrate that 1-butanol is developmental toxic only at maternal toxic doses."5.33Evaluation of developmental toxicity of 1-butanol given to rats in drinking water throughout pregnancy. ( Ema, M; Hara, H; Hirose, A; Kamata, E; Matsumoto, M, 2005)
"Ethanol may cause fetal alcohol spectrum disorders (FASD) in part by inhibiting cell adhesion mediated by the L1 neural cell adhesion molecule."1.37Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion. ( Charness, ME; Dou, X; Menkari, CE; Miller, KW; Shanmugasundararaj, S, 2011)
" The data demonstrate that 1-butanol is developmental toxic only at maternal toxic doses."1.33Evaluation of developmental toxicity of 1-butanol given to rats in drinking water throughout pregnancy. ( Ema, M; Hara, H; Hirose, A; Kamata, E; Matsumoto, M, 2005)
" Even at a maternally toxic dose, and in spite of a dose-dependent reduction in fetal weights for each isomer, the only teratogenicity observed was a slight increase in skeletal malformations (primarily rudimentary cervical ribs), seen with the highest concentration of 1-butanol."1.28Lack of selective developmental toxicity of three butanol isomers administered by inhalation to rats. ( Brightwell, WS; Burg, JR; Goad, PT; Khan, A; Nelson, BK, 1989)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199015 (60.00)18.7374
1990's5 (20.00)18.2507
2000's2 (8.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Segal, D1
Bale, AS1
Phillips, LJ1
Sasso, A1
Schlosser, PM1
Starkey, C1
Makris, SL1
Pessatto, LR1
Auharek, SA1
Gonçalves, CA1
de David, N1
Monreal, AC1
Kassuya, CA1
Antoniolli-Silva, AC1
Stefanello, MÉ1
Oliveira, RJ1
Dou, X1
Menkari, CE1
Shanmugasundararaj, S1
Miller, KW1
Charness, ME1
Ema, M1
Hara, H1
Matsumoto, M1
Hirose, A1
Kamata, E1
Wang, JG1
Xiong, CL1
Wang, SY1
Wu, YP1
Fu, YF1
Zhang, ZH1
Reddy, BV1
Boyadjieva, N1
Sarkar, DK1
Sitarek, K1
Berlińska, B1
Barański, B1
LUM, J1
MAN, EB2
SILVER, HK1
REID, WA1
JONES, WS1
Pourci, ML1
Cherruau, B1
Lacour, B1
Daniel, MA1
Evans, MA1
Klinger, G1
Bonow, A1
Hempel, E1
Klimisch, HJ1
Hellwig, J1
Pulkkinen, MO1
Nyman, S1
Hämäläinen, MM1
Mattinen, J1
Chang, CH1
Angellis, D1
Lin, TM1
Halbert, SP1
Messer, HH1
Shami, Y1
Copp, DH1
Kuznetsova, LV1
Komrakova, EA1
Tikhomirov, IuP1
Faulkner, TP1
Wiechart, JD1
Hartman, DM1
Hussain, AS1
Nelson, BK2
Brightwell, WS1
Khan, A1
Burg, JR1
Goad, PT1
Pacuszka, T1
Kościelak, J1
Smith, M1
Hopkinson, DA1
Harris, H1
Zolton, RP1
Mertz, ET1
Russell, HT1

Reviews

1 review available for 1-butanol and Pregnancy

ArticleYear
Issues in assessing the health risks of n-butanol.
    Journal of applied toxicology : JAT, 2020, Volume: 40, Issue:1

    Topics: 1-Butanol; Acetates; Animals; Embryonic Development; Environmental Exposure; Environmental Pollutant

2020

Other Studies

24 other studies available for 1-butanol and Pregnancy

ArticleYear
Effects of dichloromethane and butanol fractions of Gochnatia polymorpha floccosa in maternal reproductive outcome, embryo-fetal development and DNA integrity in mice.
    Journal of ethnopharmacology, 2017, Mar-22, Volume: 200

    Topics: 1-Butanol; Animals; Asteraceae; DNA; Female; Fetal Development; Maternal Health; Methylene Chloride;

2017
Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion.
    The Journal of biological chemistry, 2011, May-06, Volume: 286, Issue:18

    Topics: 1-Butanol; Amino Acid Substitution; Animals; Binding Sites; Cell Adhesion; Central Nervous System De

2011
Evaluation of developmental toxicity of 1-butanol given to rats in drinking water throughout pregnancy.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2005, Volume: 43, Issue:2

    Topics: 1-Butanol; Abnormalities, Drug-Induced; Administration, Oral; Animals; Bone Development; Dose-Respon

2005
[Comparison of the anti-fertility effects of four extracts from the roots of Rhynchosia volubilis Lour].
    Zhonghua nan ke xue = National journal of andrology, 2007, Volume: 13, Issue:10

    Topics: 1-Butanol; Acetates; Administration, Oral; Animals; Drugs, Chinese Herbal; Epididymis; Ethanol; Faba

2007
Effect of ethanol, propanol, butanol, and catalase enzyme blockers on beta-endorphin secretion from primary cultures of hypothalamic neurons: evidence for a mediatory role of acetaldehyde in ethanol stimulation of beta-endorphin release.
    Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:2

    Topics: 1-Butanol; 1-Propanol; Acetaldehyde; Amitrole; Animals; Azides; beta-Endorphin; Butanols; Catalase;

1995
Assessment of the effect of n-butanol given to female rats in drinking water on fertility and prenatal development of their offspring.
    International journal of occupational medicine and environmental health, 1994, Volume: 7, Issue:4

    Topics: 1-Butanol; Animals; Bone and Bones; Butanols; Embryonic and Fetal Development; Female; Fertility; Pr

1994
Serum butanol-extractable iodines in abortions.
    The Yale journal of biology and medicine, 1955, Volume: 28, Issue:2

    Topics: Abortion, Induced; Blood; Butanols; Female; Humans; Iodine; Pregnancy

1955
Butanol-extractable iodine values in the offspring of diabetic women.
    A.M.A. journal of diseases of children, 1958, Volume: 96, Issue:2

    Topics: Butanols; Diabetes Mellitus; Family; Infant, Newborn; Iodides; Iodine; Pregnancy

1958
THYROID FUNCTION IN HUMAN PREGNANCY. I. THE SIGNIFICANCE OF SERUM BUTANOL-EXTRACTABLE IODINES IN THE LAST TRIMESTER.
    American journal of obstetrics and gynecology, 1964, Oct-15, Volume: 90

    Topics: Biomedical Research; Butanols; Female; Humans; Iodine; Pregnancy; Pregnancy Complications; Pregnancy

1964
Determination of placental alkaline phosphatase phenotypes by starch-gel and acrylamide gel electrophoresis.
    Clinica chimica acta; international journal of clinical chemistry, 1984, Jun-27, Volume: 140, Issue:1

    Topics: Alkaline Phosphatase; Butanols; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Fe

1984
Quantitative comparison of maternal ethanol and maternal tertiary butanol diet on postnatal development.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:2

    Topics: Animals; Avoidance Learning; Behavior, Animal; Body Weight; Butanols; Ethanol; Exploratory Behavior;

1982
[Behaviour of Butanol-extractable iodine in serum, during and after long-time application of hormonal contraceptives (author's transl)].
    Zentralblatt fur Gynakologie, 1981, Volume: 103, Issue:1

    Topics: Adult; Butanols; Contraceptives, Oral; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormona

1981
Studies on the prenatal toxicity of 3-methyl-1-butanol and 2-methyl-1-propanol in rats and rabbits following inhalation exposure.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 27, Issue:1

    Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Animals; Body Weight; Butanols; Female; Fet

1995
Proton NMR spectroscopy of the phospholipids in human uterine smooth muscle and placenta.
    Gynecologic and obstetric investigation, 1998, Volume: 46, Issue:4

    Topics: Adult; Butanols; Cholesterol; Fatty Acids; Female; Humans; Labor, Obstetric; Magnetic Resonance Spec

1998
Identification of a butanol-extractable human placenta-specific antigen with alkaline phosphatase activity.
    Journal of immunology (Baltimore, Md. : 1950), 1976, Volume: 117, Issue:1

    Topics: Absorption; Alkaline Phosphatase; Antigens; Butanols; Epitopes; Female; Humans; Immune Sera; Placent

1976
Immunological comparison of various human pregnancy-associated plasma proteins.
    International archives of allergy and applied immunology, 1975, Volume: 48, Issue:1

    Topics: Alkaline Phosphatase; Animals; Antibody Specificity; Antigens; Blood Proteins; Butanols; Cetylpyridi

1975
Stimulation by ATP of alkaline phosphatase in placental plasma membranes.
    Biochimica et biophysica acta, 1975, May-23, Volume: 391, Issue:1

    Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphatases; Adenosine Triphosphate; Alkaline Phosphatase; A

1975
[Gas-chromatographic methods of analysis of methyl and butyl ethers of acrylic and methacrylic acids and their metabolites in biological media].
    Gigiena truda i professional'nye zabolevaniia, 1991, Issue:12

    Topics: Acrylates; Amniotic Fluid; Animals; Butanols; Chromatography, Gas; Ethers; Female; Humans; Liver; Lu

1991
The effects of prenatal tertiary butanol administration in CBA/J and C57BL/6J mice.
    Life sciences, 1989, Volume: 45, Issue:21

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Butanols; Ethanol; Female; Fetal Resorption; Fetu

1989
Lack of selective developmental toxicity of three butanol isomers administered by inhalation to rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1989, Volume: 12, Issue:3

    Topics: Administration, Inhalation; Animals; Body Weight; Butanols; Eating; Female; Fetus; Gestational Age;

1989
Developmental neurotoxicology of in utero exposure to industrial solvents in experimental animals.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Butanols; Carbon Disulfide; Chemical Industry; Chloroform; Female; Formaldehyde; Methyl n-B

1986
A and B blood group specificities of stroma fractions of cord blood erythrocytes.
    Archivum immunologiae et therapiae experimentalis, 1971, Volume: 19, Issue:5

    Topics: ABO Blood-Group System; Butanols; Epitopes; Erythrocytes; Female; Fetal Blood; Glycolipids; Humans;

1971
Studies on the properties of the human alcohol dehydrogenase isozymes determined by the different loci ADH1, ADH2, ADH3.
    Annals of human genetics, 1973, Volume: 37, Issue:1

    Topics: 1-Propanol; Acetaldehyde; Alcohol Oxidoreductases; Alcohols; Aldehyde Oxidoreductases; Butanols; Chl

1973
Assay of human plasminogen in plasma by affinity chromatography.
    Clinical chemistry, 1972, Volume: 18, Issue:7

    Topics: Adolescent; Adult; Aged; Aminobenzoates; Butanols; Chromatography, Affinity; Female; Hodgkin Disease

1972