1-butanol has been researched along with Multiple Sclerosis in 1 studies
1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.
butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myelin basic protein (MBP) is a candidate autoantigen in multiple sclerosis (MS)." | 3.77 | The HLA-DP2 protein binds the immunodominant epitope from myelin basic protein, MBP85-99, with high affinity. ( Hansen, BE; Jakobsen, BK; Madsen, HO; Nielsen, CH; Ryder, LP; Svejgaard, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, BE | 1 |
| Nielsen, CH | 1 |
| Madsen, HO | 1 |
| Ryder, LP | 1 |
| Jakobsen, BK | 1 |
| Svejgaard, A | 1 |
1 other study available for 1-butanol and Multiple Sclerosis
| Article | Year |
|---|---|
The HLA-DP2 protein binds the immunodominant epitope from myelin basic protein, MBP85-99, with high affinity.
Topics: 1-Butanol; Amino Acid Sequence; Animals; Cells, Cultured; Drosophila melanogaster; Enzyme-Linked Imm | 2011 |