1-butanol has been researched along with Elevated Cholesterol in 8 studies
1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.
butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effects of lifibrol on serum lipids in adult patients with primary hypercholesterolemia." | 9.08 | Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. Lifibrol Study Group. ( Francom, SF; Hughes, GS; Jungbluth, GL; Locker, PK, 1995) |
| "To determine the effects of lifibrol on serum lipids in adult patients with primary hypercholesterolemia." | 5.08 | Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. Lifibrol Study Group. ( Francom, SF; Hughes, GS; Jungbluth, GL; Locker, PK, 1995) |
| "Lifibrol is a potent lipid-lowering drug with an unknown mechanism of action." | 2.75 | Lifibrol as a model compound for a novel lipid-lowering mechanism of action. ( Berthold, HK; Gouni-Berthold, I; Sudhop, T; von Bergmann, K, 2010) |
| "Lifibrol is a powerful cholesterol-lowering drug of unknown mechanism of action." | 2.69 | Effect of lifibrol on the metabolism of low density lipoproteins and cholesterol. ( Adams-Huet, B; Blumenschein, S; Carter, NB; Grundy, SM; Laeis, P; Lindenthal, B; Lutjohann, D; Simatupang, A; Vega, GL; von Bergmann, J; von Bergmann, K, 1999) |
| "Lifibrol was generally well tolerated in all dosage groups and no serious adverse events were reported." | 2.67 | Safety and efficacy of lifibrol upon four-week administration to patients with primary hypercholesterolaemia. ( Augustin, J; Elsässer, R; Gertz, B; Heil, M; Schmidt, C; Schwandt, P; Seibel, K, 1994) |
| "Continuous HFD feeding caused hyperlipidemia, oxidative stress and liver damage in mice." | 1.37 | Hypolipidemic effect of n-butanol Extract from Asparagus officinalis L. in mice fed a high-fat diet. ( Pang, X; Qu, W; Wang, J; Zhang, W; Zhao, J; Zhu, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, X | 1 |
| Zhang, W | 1 |
| Pang, X | 1 |
| Wang, J | 1 |
| Zhao, J | 1 |
| Qu, W | 1 |
| Berthold, HK | 1 |
| Sudhop, T | 1 |
| von Bergmann, K | 2 |
| Gouni-Berthold, I | 1 |
| Klein, RL | 1 |
| Zilversmit, DB | 1 |
| Locker, PK | 1 |
| Jungbluth, GL | 1 |
| Francom, SF | 1 |
| Hughes, GS | 1 |
| Schwandt, P | 1 |
| Elsässer, R | 1 |
| Schmidt, C | 1 |
| Gertz, B | 1 |
| Heil, M | 1 |
| Augustin, J | 1 |
| Seibel, K | 1 |
| Winkler, K | 1 |
| Schäfer, JR | 1 |
| Klima, B | 1 |
| Nuber, C | 1 |
| Sattler, A | 1 |
| Friedrich, I | 1 |
| Köster, W | 1 |
| Steinmetz, A | 1 |
| Wieland, H | 1 |
| März, W | 1 |
| Vega, GL | 1 |
| Grundy, SM | 1 |
| Blumenschein, S | 1 |
| Carter, NB | 1 |
| Laeis, P | 1 |
| Lindenthal, B | 1 |
| von Bergmann, J | 1 |
| Simatupang, A | 1 |
| Lutjohann, D | 1 |
| Adams-Huet, B | 1 |
| Tsi, D | 1 |
| Tan, BK | 1 |
5 trials available for 1-butanol and Elevated Cholesterol
| Article | Year |
|---|---|
Lifibrol as a model compound for a novel lipid-lowering mechanism of action.
Topics: Adult; Anticholesteremic Agents; Apolipoprotein B-100; Butanols; Cholesterol; Cholesterol, HDL; Chol | 2010 |
Lifibrol: a novel lipid-lowering drug for the therapy of hypercholesterolemia. Lifibrol Study Group.
Topics: Adolescent; Adult; Aged; Apolipoproteins; Bile Acids and Salts; Butanols; Cholesterol, LDL; Dose-Res | 1995 |
Safety and efficacy of lifibrol upon four-week administration to patients with primary hypercholesterolaemia.
Topics: Anticholesteremic Agents; Butanols; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, | 1994 |
Lifibrol enhances the low density lipoprotein apolipoprotein B-100 turnover in patients with hypercholesterolemia and mixed hyperlipidemia.
Topics: Adult; Anticholesteremic Agents; Apolipoproteins B; Butanols; Female; Gas Chromatography-Mass Spectr | 1999 |
Effect of lifibrol on the metabolism of low density lipoproteins and cholesterol.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Butanols; Cholesterol; Cholesterol, HDL; Choleste | 1999 |
3 other studies available for 1-butanol and Elevated Cholesterol
| Article | Year |
|---|---|
Hypolipidemic effect of n-butanol Extract from Asparagus officinalis L. in mice fed a high-fat diet.
Topics: 1-Butanol; Animals; Antioxidants; Asparagus Plant; Cholesterol; Cholesterol, LDL; Diet, High-Fat; Hy | 2011 |
Direct determination of human and rabbit apolipoprotein B selectively precipitated with butanol-isopropyl ether.
Topics: Animals; Apolipoproteins B; Butanols; Ethers; Female; Humans; Hypercholesterolemia; Lipids; Lipoprot | 1984 |
The mechanism underlying the hypocholesterolaemic activity of aqueous celery extract, its butanol and aqueous fractions in genetically hypercholesterolaemic RICO rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anticholesteremic Agents; Apiaceae; Bile Acids | 2000 |