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1-butanol and Astrocytoma

1-butanol has been researched along with Astrocytoma in 4 studies

1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.
butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"1-Butanol, which is a substrate for PLD and inhibits PA formation, inhibited carbachol-induced cell proliferation and the underlying intracellular signaling, whereas its analog tert-butanol, which is a poor substrate for PLD, was much less effective."5.32Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells. ( Costa, LG; Guizzetti, M; Kim, Y; Thompson, BD; VanDeMark, K, 2004)
"1-Butanol, which is a substrate for PLD and inhibits PA formation, inhibited carbachol-induced cell proliferation and the underlying intracellular signaling, whereas its analog tert-butanol, which is a poor substrate for PLD, was much less effective."1.32Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells. ( Costa, LG; Guizzetti, M; Kim, Y; Thompson, BD; VanDeMark, K, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, SY1
Ahn, BH2
Min, KJ1
Lee, YH1
Joe, EH1
Min, DS2
Guizzetti, M1
Thompson, BD1
Kim, Y1
VanDeMark, K1
Costa, LG1
Min, G1
Bae, YS2
Purkiss, JR1

Other Studies

4 other studies available for 1-butanol and Astrocytoma

ArticleYear
Phospholipase D isozymes mediate epigallocatechin gallate-induced cyclooxygenase-2 expression in astrocyte cells.
    The Journal of biological chemistry, 2004, Sep-10, Volume: 279, Issue:37

    Topics: 1-Butanol; Animals; Astrocytes; Astrocytoma; Blotting, Western; Carbazoles; Catechin; Cell Line, Tum

2004
Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells.
    Journal of neurochemistry, 2004, Volume: 90, Issue:3

    Topics: 1-Butanol; Astrocytoma; Carbachol; Cell Division; Cell Line, Tumor; Cholinergic Agonists; DNA; Enzym

2004
Phospholipase D is activated and phosphorylated by casein kinase-II in human U87 astroglioma cells.
    Experimental & molecular medicine, 2006, Feb-28, Volume: 38, Issue:1

    Topics: 1-Butanol; Astrocytoma; Blotting, Western; Casein Kinase II; Cell Line, Tumor; Cell Proliferation; D

2006
Protein kinase C modulation of phosphoinositidase C in 1321N1 human astrocytoma cells.
    Biochemical Society transactions, 1996, Volume: 24, Issue:1

    Topics: Astrocytoma; Butanols; Cell Line; Enzyme Inhibitors; Histamine; Humans; Indoles; Inositol 1,4,5-Tris

1996