1-anilino-8-naphthalenesulfonate has been researched along with Tay-Sachs Disease in 2 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
Tay-Sachs Disease: An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis, dementia, and blindness. It is caused by mutation in the alpha subunit of the HEXOSAMINIDASE A resulting in lipid-laden ganglion cells. It is also known as the B variant (with increased HEXOSAMINIDASE B but absence of hexosaminidase A) and is strongly associated with Ashkenazic Jewish ancestry.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
SPIEGEL-ADOLF, M | 1 |
BAIRD, H | 1 |
KOLLIAS, D | 1 |
Gandarias, JM | 1 |
Lacort, M | 1 |
de Nicolás, MA | 1 |
Ochoa, B | 1 |
1 review available for 1-anilino-8-naphthalenesulfonate and Tay-Sachs Disease
Article | Year |
---|---|
[Functions and pathological aspects of lysosomes].
Topics: alpha-Glucosidases; Animals; Autophagy; beta-N-Acetylhexosaminidases; Cytoplasmic Granules; Endocyto | 1985 |
1 other study available for 1-anilino-8-naphthalenesulfonate and Tay-Sachs Disease
Article | Year |
---|---|
Lipases in the cerebrospinal fluid in various neurological conditions, especially infantile amaurotic idiocy (Tay-Sachs disease).
Topics: Cerebrospinal Fluid; Intellectual Disability; Lipase; Nervous System Diseases; Neuronal Ceroid-Lipof | 1957 |