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1-anilino-8-naphthalenesulfonate and Tay-Sachs Disease

1-anilino-8-naphthalenesulfonate has been researched along with Tay-Sachs Disease in 2 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Tay-Sachs Disease: An autosomal recessive neurodegenerative disorder characterized by the onset in infancy of an exaggerated startle response, followed by paralysis, dementia, and blindness. It is caused by mutation in the alpha subunit of the HEXOSAMINIDASE A resulting in lipid-laden ganglion cells. It is also known as the B variant (with increased HEXOSAMINIDASE B but absence of hexosaminidase A) and is strongly associated with Ashkenazic Jewish ancestry.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SPIEGEL-ADOLF, M1
BAIRD, H1
KOLLIAS, D1
Gandarias, JM1
Lacort, M1
de Nicolás, MA1
Ochoa, B1

Reviews

1 review available for 1-anilino-8-naphthalenesulfonate and Tay-Sachs Disease

ArticleYear
[Functions and pathological aspects of lysosomes].
    Revista clinica espanola, 1985, Volume: 176, Issue:7

    Topics: alpha-Glucosidases; Animals; Autophagy; beta-N-Acetylhexosaminidases; Cytoplasmic Granules; Endocyto

1985

Other Studies

1 other study available for 1-anilino-8-naphthalenesulfonate and Tay-Sachs Disease

ArticleYear
Lipases in the cerebrospinal fluid in various neurological conditions, especially infantile amaurotic idiocy (Tay-Sachs disease).
    Confinia neurologica, 1957, Volume: 17, Issue:5

    Topics: Cerebrospinal Fluid; Intellectual Disability; Lipase; Nervous System Diseases; Neuronal Ceroid-Lipof

1957