Page last updated: 2024-10-21

1-anilino-8-naphthalenesulfonate and Pancreatic Insufficiency

1-anilino-8-naphthalenesulfonate has been researched along with Pancreatic Insufficiency in 186 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Research Excerpts

ExcerptRelevanceReference
"Fifteen patients with cystic fibrosis and pancreatic insufficiency were studied during four randomised seven day treatment periods in which they received only pancreatic supplement (Pancrelipase, 27 capsules per day) or supplement plus cimetidine (20 mg/kg body weight/24 h) or sodium bicarbonate (15 g/m2/24 h) alone or in combination."9.05Effect of cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis. ( Bell, L; Corey, ML; Durie, PR; Forstner, GG; Linton, W, 1980)
"Forty-six subjects (20 chronic pancreatitis, 7 chronic liver disease, 7 recovered from acute pancreatitis, 2 Crohn's disease, and 10 healthy controls) classified by S-C test as having normal pancreatic function (26 subjects), or moderate (10 subjects) and severe (10 cases) pancreatic insufficiency, were given, on different days, 1 g of oral PABA or 348 mg of oral fluorescein dilaurate."7.67Serum PABA and fluorescein in the course of Bz-Ty-PABA and pancreolauryl test as an index of exocrine pancreatic insufficiency. ( Angelini, G; Benini, L; Brocco, G; Cavallini, G; Chech, G; Dalle Molle, L; Micciolo, R; Piubello, W; Riela, A; Vantini, I, 1985)
" In this controlled randomized study, 8 hospitalized patients with severe exocrine pancreatic insufficiency and considerable steatorrhoea (greater than 15 g faecal fat/day) were treated with a conventional pancreatic enzyme preparation (Pankreon 700; 3 X 3 dragees daily), with (300 mg) and without cimetidine before meals, and with a new pH-sensitive enzyme preparation (Kreon; 3 X 6 capsules daily) comprising acid-protected granules."5.06Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage? ( Creutzfeldt, W; Göke, B; Lankisch, PG; Lembcke, B, 1986)
"Fifteen patients with cystic fibrosis and pancreatic insufficiency were studied during four randomised seven day treatment periods in which they received only pancreatic supplement (Pancrelipase, 27 capsules per day) or supplement plus cimetidine (20 mg/kg body weight/24 h) or sodium bicarbonate (15 g/m2/24 h) alone or in combination."5.05Effect of cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis. ( Bell, L; Corey, ML; Durie, PR; Forstner, GG; Linton, W, 1980)
"Forty-six subjects (20 chronic pancreatitis, 7 chronic liver disease, 7 recovered from acute pancreatitis, 2 Crohn's disease, and 10 healthy controls) classified by S-C test as having normal pancreatic function (26 subjects), or moderate (10 subjects) and severe (10 cases) pancreatic insufficiency, were given, on different days, 1 g of oral PABA or 348 mg of oral fluorescein dilaurate."3.67Serum PABA and fluorescein in the course of Bz-Ty-PABA and pancreolauryl test as an index of exocrine pancreatic insufficiency. ( Angelini, G; Benini, L; Brocco, G; Cavallini, G; Chech, G; Dalle Molle, L; Micciolo, R; Piubello, W; Riela, A; Vantini, I, 1985)
"The effect of the addition of sodium bicarbonate, aluminum hydroxide, magnesium hydroxide, calcium carbonate, or cimetidine to supplemental pancreatic enzyme therapy was investigated in patients with severe exocrine pancreatic insufficiency."3.66Pancreatic enzyme replacement: the effect of antacids or cimetidine. ( Graham, DY, 1982)
"The Food and Drug Administration in 2006 required that all pancreatic enzyme products demonstrate bioavailability of lipase, amylase, and protease in the proximal small intestine."2.94Study of the gastrointestinal bioavailability of a pancreatic extract product (Zenpep) in chronic pancreatitis patients with exocrine pancreatic insufficiency. ( Karnik, N; Lieb, JG; Patel, D; Toskes, PP, 2020)
" Adverse events were mostly gastrointestinal in nature and were more common in the group receiving NM-BL."2.82Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial. ( Ahrens, RC; Forssmann, K; Graff, G; Heubi, JE; Jain, R; Schaeffer, D; Sollo, N; Strausbaugh, S; Witte, S, 2016)
" PA bioavailability estimates for CF subjects without pancreatic enzyme administration (1."2.80Malabsorption blood test: Assessing fat absorption in patients with cystic fibrosis and pancreatic insufficiency. ( Barrett, JS; Mascarenhas, MR; Mondick, J; Schall, JI; Stallings, VA; Wilson, M, 2015)
" All of the patients were required to discontinue their long-term use of porcine PERTs at the time of enrollment."2.77Liprotamase long-term safety and support of nutritional status in pancreatic-insufficient cystic fibrosis. ( Borowitz, D; Brettman, LR; Campion, M; Stevens, C; Thompson, H; Wilschanski, M, 2012)
" At the other dosing levels, the mean coefficient of fat and nitrogen absorption increases were 19."2.72Safety and preliminary clinical activity of a novel pancreatic enzyme preparation in pancreatic insufficient cystic fibrosis patients. ( Ahrens, R; Aitken, ML; Borowitz, D; Dunitz, J; Goss, CH; Hayes, D; Hendeles, L; Konstan, MW; Mahl, TC; Moss, R; Murray, FT; Newman, L; O'Rourke, A; Oermann, CM; Orenstein, D; Stevens, C; Wagener, J; Young, KR, 2006)
" Excellent fat and protein absorption was achieved with minimal adverse events and safe doses."2.71Ultrase MT12 and Ultrase MT20 in the treatment of exocrine pancreatic insufficiency in cystic fibrosis: safety and efficacy. ( Colin, P; Duggan, C; Eigen, H; Konstan, MW; Sherman, JM; Stern, RC; Trout, JR; Wagener, JS; Wohl, ME, 2004)
"A dose-response relationship between the amount of lipase administered with each meal and a reduction in faecal fat was not evident."2.68Lack of dose-response with Pancrease MT for the treatment of exocrine pancreatic insufficiency in adults. ( Graham, DY; Opekun, AR; Sutton, FM, 1997)
"Chronic pancreatitis was alcohol-related in 23 patients, previous surgery was performed in 9, 16 had diabetes and all had steatorrhoea (fat balance > 10g/24h)."2.68Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis. ( Buedts, K; Cremer, M; Delhaye, M; Gohimont, AC; Meuris, S, 1996)
" A high-strength preparation is thought to release relatively less enzyme activity in the small intestine, forcing patients to increase their dosage and possibly creating a dangerous enzyme hyperconcentration in the large intestine."2.68High- versus low-lipase acid-resistant enzyme preparations in cystic fibrosis: a crossover randomized clinical trial. ( Cabrini, G; Lancellotti, L; Mastella, G; Zanolla, L, 1996)
" Capsule dosage was adjusted to a ratio of approximately 3:1."2.67Comparison between a standard pancreatic supplement and a high enzyme preparation in cystic fibrosis. ( Bowden, MW; Byers, CA; Dodge, JA; Guilford, SA; McCracken, KJ; Morrison, G; Morrison, JM; Redmond, AO, 1992)
" Finally, the higher potency preparations were more effective per capsule and reduced capsule dosage is therefore attainable."2.67Comparative in vitro and in vivo studies of enteric-coated pancrelipase preparations for pancreatic insufficiency. ( Clague, A; Cleghorn, GJ; Shepherd, RW; Thomson, M, 1993)
"In the past 10 years, treatment of acute pancreatitis has moved towards a multidisciplinary, tailored, and minimally invasive approach."2.66Acute pancreatitis. ( Besselink, MG; Boermeester, MA; Bouwense, SA; Boxhoorn, L; Bruno, MJ; van Santvoort, HC; Verdonk, RC; Voermans, RP, 2020)
"In an attempt to critically examine the therapeutic efficacy of pH-sensitive enteric-coated pancreatic enzyme preparations in patients with pancreatic insufficiency due to cystic fibrosis, postprandial duodenal concentration and recovery of orally administered pancreatic enzymes, duodenal pH, and coefficient of fat absorption were determined in eight cases after ingestion of equivalent dosage of enteric-coated as well as conventional enzyme preparations."2.66Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis. ( Appler, M; Dutta, SK; Hubbard, VS, 1988)
" Bioavailability was measured by using a double intubation method in 13 patients with severe pancreatic insufficiency."2.66[Comparison of fungal lipase and pancreatic lipase in exocrine pancreatic insufficiency in man. Study of their in vitro properties and intraduodenal bioavailability]. ( Bommelaer, G; Bouisson, M; Moreau, J; Pignal, F; Ribet, A; Saint-Marc-Girardin, MF, 1988)
"Pancreatic insufficiency is a major consequence of pancreatic diseases leading to a loss of pancreatic parenchyma, obstruction of the main pancreatic duct, decreased pancreatic stimulation, or acid-mediated inactivation of pancreatic enzymes."2.47Pancreatic exocrine insufficiency: diagnosis and treatment. ( Domínguez-Muñoz, JE, 2011)
" While dosage requirements vary widely and therefore have to be tried out individually, the choice of the adequate preparation should be influenced by the realization of the physiological and pathophysiological characteristics of the individual patient and the pharmaceutical characteristics of the different supplements."2.38[Clinical and pharmacological aspects of pancreatic enzyme substitution therapy]. ( Fölsch, UR; Löser, C, 1991)
"To establish the diagnosis of acute pancreatitis the estimation of amylase in serum and urine, lipase and radio-immunoreactive trypsin in the serum are useful."2.36[Examination of pancreatic function in children with special reference to the PABA-test (author's transl)]. ( Dockter, G; Sitzmann, FC, 1980)
"CFA has been used to assess treatment of pancreatic insufficiency but does not correlate with pancreatic enzyme replacement therapy dose."1.91Validation of an omega-3 substrate challenge absorption test as an indicator of global fat lipolysis. ( Borowitz, DS; Freedman, SD; Gallotto, R; Pierzynowska, K; Pierzynowski, S; Sathe, M; Zaworski, K, 2023)
"Exocrine pancreatic insufficiency was proposed as the underlying cause."1.43Exocrine pancreatic function in children with Alagille syndrome. ( Gliwicz, D; Jankowska, I; Lisowska, A; Miśkiewicz-Chotnicka, A; Walkowiak, J; Wierzbicka, A, 2016)
" An individualized therapy is required that includes high dosage of enzymatic units, usage of enteric coating, and addition of gastric proton pump inhibitors."1.43Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency. ( Aldag, I; Brock, A; Edskes, S; Hartmann, M; Herzog, T; Schnekenburger, J; Uhl, W, 2016)
"In this study population, no correlation between an enzyme dosage and the degree of fat malabsorption was found; however, a CFA below 85% was found in 24% of the measurements."1.42Pancreatic Enzyme Replacement Therapy and Coefficient of Fat Absorption in Children and Adolescents With Cystic Fibrosis. ( Houwen, RH; van der Ent, CK; Woestenenk, JW, 2015)
" Tests make it possible to choose the initial pancreatic enzyme dosage and are beneficial during the treatment for pancreatic enzyme dose correction."1.40[The clinical application of 13C-breath tests in pancreatic diseases]. ( Cherniavskiĭ, VV, 2014)
"Patients attending US cystic fibrosis programs achieving highest nutritional outcomes, measured by mean BMI percentile, have higher enzyme dosing than those attending programs at lower performance levels."1.40Pancreatic enzyme replacement therapy dosing and nutritional outcomes in children with cystic fibrosis. ( Haupt, ME; Kwasny, MJ; McColley, SA; Schechter, MS, 2014)
"Exocrine pancreatic insufficiency was irreversible in alcoholic rats without CP after alcohol withdrawal."1.36Irreversible exocrine pancreatic insufficiency in alcoholic rats without chronic pancreatitis after alcohol withdrawal. ( Huang, Z; Li, J; Liu, R; Tang, C; Wang, R; Zhou, C, 2010)
"Pancreatitis is a rare complication among patients with CF."1.33Pancreatitis among patients with cystic fibrosis: correlation with pancreatic status and genotype. ( De Boeck, K; Kerem, E; Proesmans, M; Weren, M, 2005)
"Among the 36 patients with alcoholic pancreatitis, most had impaired pancreatic function at both duodenal intubation (8/8, 100%) and at AACT (22/28, 78."1.32Exocrine pancreatic function after alcoholic or biliary acute pancreatitis. ( Gullo, L; Migliori, M; Pezzilli, R; Tomassetti, P, 2004)
"Chronic pancreatitis is a common cause of exocrine pancreatic insufficiency (EPI) in humans and cats but is rarely recognised in dogs in which pancreatic acinar atrophy (PAA) is reportedly more common."1.32Exocrine pancreatic insufficiency as an end stage of pancreatitis in four dogs. ( Watson, PJ, 2003)
" To evaluate the relationship between fibrosing colonopathy and supplemental pancreatic enzymes we reviewed our dosing of enzymes prior to fibrosing colonopathy development and then evaluated the subsequent effect of drastically reducing pancreatic enzyme dose."1.30Pancreatic enzyme supplementation in cystic fibrosis patients before and after fibrosing colonopathy. ( Chong, SK; Heilman, DK; Hollingsworth, J; Maguiness, KM; Stevens, JC, 1998)
"Treatment of human exocrine pancreatic insufficiency is suboptimal."1.30Effect of bacterial or porcine lipase with low- or high-fat diets on nutrient absorption in pancreatic-insufficient dogs. ( DiMango, EP; Mizumoto, A; Rerknimitr, R; Sarr, MG; Suzuki, A, 1999)
" Therefore, we examined the dose-response of endogenous lipase on fat absorption."1.29Effect of replenished lipase on postcibal absorption of fat in a canine model of pancreatic insufficiency. ( Doty, JE; Gu, YG; Meyer, JH, 1994)
"Pancreatic insufficiency was created by pancreatic duct ligation, and the duodenal, jejunal and ileal contents were sampled through cannulas before a normal meal and 0."1.28Total pancreatic insufficiency in pigs: a model to study intestinal enzymes and plasma levels of digestive hormones after pancreatic supplementation by a whole pancreas preparation. ( Abello, J; Cuber, JC; Junien, JL; Pascaud, X; Rozé, C; Simoes-Nunes, C, 1989)
"Pancreatic insufficiency was associated with significantly (p less than 0."1.27Role of nonpancreatic lipolytic activity in exocrine pancreatic insufficiency. ( Abrams, CK; Dutta, SK; Hamosh, M; Hamosh, P; Hubbard, VS, 1987)
"Patients with pancreatic insufficiency have a ravenous appetite but fail to thrive from malnutrition."1.26[Exocrine pancreatic insufficiency (author's transl)]. ( Götze, H, 1980)

Research

Studies (186)

TimeframeStudies, this research(%)All Research%
pre-199048 (25.81)18.7374
1990's55 (29.57)18.2507
2000's30 (16.13)29.6817
2010's40 (21.51)24.3611
2020's13 (6.99)2.80

Authors

AuthorsStudies
Olsen, MF1
Kjøller-Svarre, MS1
Møller, G1
Katzenstein, TL1
Nielsen, BU1
Pressler, T1
Lewis, JI1
Mathiesen, IH1
Mølgaard, C1
Faurholt-Jepsen, D1
Erchinger, F1
Tjora, E1
Nordaas, IK1
Dimcevski, G1
Olesen, SS1
Jensen, N1
Dahl, EE1
Borch, A1
Nøjgaard, C1
Novovic, S1
Barauskas, G1
Ignatavicius, P1
Vujasinovic, M1
Lőhr, M1
Laukkarinen, J1
Parhiala, M1
Drewes, AM1
Engjom, T1
Bejjani, J1
Allain, DC1
Hart, PA2
Freedman, SD2
Zaworski, K1
Pierzynowska, K2
Pierzynowski, S4
Gallotto, R1
Sathe, M1
Borowitz, DS1
Wang, F1
Wang, H3
Fan, J1
Zhang, Y1
Zhao, Q1
Lieb, JG1
Patel, D1
Karnik, N1
Toskes, PP1
Boxhoorn, L1
Voermans, RP1
Bouwense, SA1
Bruno, MJ2
Verdonk, RC1
Boermeester, MA1
van Santvoort, HC1
Besselink, MG1
Maev, IV2
Kucheryavyy, YA2
Gubergrits, NB2
Bonnacker, I1
Shelest, EA1
Janssen-van Solingen, GP1
Domínguez-Muñoz, JE3
Petersen, KU1
Malfertheiner, P2
Mössner, J2
Güven, B1
Turan, NB1
Öner, AF1
Karaman, K1
Çetin, M1
Grimmelmann, I1
Momma, M1
Zimmer, L1
Hassel, JC1
Heinzerling, L1
Pföhler, C1
Loquai, C1
Ruini, C1
Utikal, J1
Thoms, KM1
Kähler, KC1
Eigentler, T1
Herbst, RA1
Meier, F1
Debus, D1
Berking, C1
Kochanek, C1
Ugurel, S1
Gutzmer, R1
Pierzynowski, SG3
Socha-Banasiak, A1
Sobol, M1
Skiba, G1
Raj, S1
Dovban, O1
Ushakova, G4
Woliński, J1
Mosiichuk, N1
Szczurek-Janicka, P1
Pieszka, M1
Kamyczek, M1
Święch, E1
Shmigel, H2
Sonta, M1
Czkwianianc, E1
Alkaade, S1
Vareedayah, AA1
Venuti, E1
Shishmarev, D1
Kuchel, PW1
Dutt, S1
Blumenthal, CS1
Gaskin, KJ3
Yilmaz, A1
Hagberg, L1
Dehghani, L1
Mikail, N1
Kramkimel, N1
Soyer, P1
Lebtahi, R1
Mallone, R1
Larger, E1
Khatkov, IE1
Abdulkhakov, SR1
Alekseenko, SA1
Alikhanov, RB1
Bakulin, IG1
Bakulina, NV1
Baranovskiy, AY1
Beloborodova, EV1
Belousova, EA1
Voskanyan, SE1
Vinokurova, LV1
Grinevich, VB1
Darvin, VV1
Dubtsova, EA1
Dyuzheva, TG1
Egorov, VI1
Efanov, MG1
Izrailov, RE1
Korobka, VL1
Kotiv, BN1
Kokhanenko, NY1
Livzan, MA1
Lyadov, VK1
Nikolskaya, KA1
Osipenko, MF2
Pasechnikov, VD1
Plotnikova, EY1
Sablin, OA1
Simanenkov, VI1
Tsvirkun, VV1
Tsukanov, VV1
Shabunin, AV1
Bordin, DS1
Salhi, A1
Amara, S1
Mansuelle, P1
Puppo, R1
Lebrun, R1
Gontero, B1
Aloulou, A3
Carrière, F6
Pongprasobchai, S1
Usborne, AL1
Smith, AT1
Engle, SK1
Watson, DE1
Sullivan, JM1
Walgren, JL1
Haupt, ME1
Kwasny, MJ1
Schechter, MS1
McColley, SA1
Kahl, S1
Schütte, K1
Glasbrenner, B1
Mayerle, J1
Simon, P1
Henniges, F3
Sander-Struckmeier, S2
Lerch, MM2
Bénarouche, A1
Point, V1
Cavalier, JF1
Rouse, R1
Zhang, L1
Shea, K1
Zhou, H1
Xu, L1
Stewart, S1
Rosenzweig, B1
Zhang, J1
Goncharova, K3
Grujic, D1
Kirko, S1
Szwiec, K4
Wang, J1
Kovalenko, T3
Osadchenko, I3
Fedkiv, O3
Majda, B1
Prykhodko, O4
Crosby, J1
Bellin, MD1
Radosevich, DM1
Chinnakotla, S1
Dunn, TB1
Pruett, TL1
Freeman, ML1
Beilman, GJ1
Schwarzenberg, SJ1
Cherniavskiĭ, VV1
Lozinska, L1
Sureda, EA1
Podgurniak, P1
Weström, B4
Mascarenhas, MR1
Mondick, J1
Barrett, JS1
Wilson, M1
Stallings, VA2
Schall, JI2
Woestenenk, JW1
van der Ent, CK1
Houwen, RH1
Lukashevich, GM1
Schué, M1
Puccinelli, D2
Milano, S1
Delchambre, C1
Leblond, Y2
Laugier, R4
Lowe, ME1
Whitcomb, DC1
Yang, W1
Gao, J1
Tai, Y1
Chen, M1
Huang, L1
Wen, S1
Huang, Z2
Liu, R2
Li, J2
Tang, C2
Conwell, DL1
Bolton, TA1
Cook, A1
Steiner, JM2
Fosgate, GT1
Heubi, JE1
Schaeffer, D1
Ahrens, RC1
Sollo, N1
Strausbaugh, S1
Graff, G1
Jain, R1
Witte, S1
Forssmann, K1
Brock, A1
Aldag, I1
Edskes, S1
Hartmann, M1
Herzog, T1
Uhl, W1
Schnekenburger, J1
Campbell, JA1
Sanders, DS1
Francis, KA1
Kurien, M1
Lee, S1
Taha, H1
Ramadas, A1
Joy, D1
Hopper, AD1
Gliwicz, D1
Jankowska, I1
Wierzbicka, A1
Miśkiewicz-Chotnicka, A1
Lisowska, A2
Walkowiak, J2
Alfaro Cruz, L1
Parniczky, A1
Mayhew, A1
Hornung, LN1
Lin, TK1
Palermo, JJ1
Jackson, K1
Abu-El-Haija, M1
Venzhina, IuIu1
Löhr, JM1
Hummel, FM1
Pirilis, KT1
Steinkamp, G1
Körner, A1
Zhou, C1
Wang, R1
Turki, S1
Mrabet, G1
Jabloun, Z1
Destain, J1
Thonart, P1
Kallel, H1
Watson, PJ2
Archer, J1
Roulois, AJ1
Scase, TJ1
Herrtage, ME1
Keller, J4
Brückel, S1
Jahr, C1
Layer, P6
Wier, HA1
Kuhn, RJ1
Borowitz, D4
Stevens, C3
Brettman, LR2
Campion, M2
Chatfield, B1
Cipolli, M1
Wilschanski, M1
Thompson, H1
Hagedorn, J1
Svendsen, A1
Borch, K1
Otzen, DE1
Valverde Piedra, JL2
Gruijc, D2
Szymanczyk, S1
Swieboda, P2
Kruszewska, D3
Filip, R2
Botermans, J2
Svendsen, J2
Skibo, G2
Proesmans, M2
De Boeck, K2
Gewert, K1
Holowachuk, SA1
Rippe, C1
Gregory, PC2
Erlanson-Albertsson, C1
Olivecrona, G1
Piedra, JV1
Nousia-Arvanitakis, S1
Piotrowski, R1
Strzykala, K1
Bychowiec, B1
Songin, T1
Galli-Tsinopoulou, A1
Sands, D1
Pidonia, I1
Krawczynski, M1
Milanowski, A1
Herzig, KH1
Migliori, M1
Pezzilli, R1
Tomassetti, P1
Gullo, L2
Mosler, K1
von Kries, R1
Vermeer, C1
Saupe, J1
Schmitz, T1
Schuster, A1
El-Hodhod, MA1
Nassar, MF1
Hetta, OA1
Gomaa, SM1
Konstan, MW3
Stern, RC1
Trout, JR1
Sherman, JM1
Eigen, H1
Wagener, JS1
Duggan, C1
Wohl, ME1
Colin, P1
Weren, M1
Kerem, E2
Grandval, P1
Renou, C1
Creutzfeldt, W2
Gleichmann, D1
Otto, J2
Stöckmann, F1
Maisonneuve, P1
Lankisch, PG3
Schulthess, G1
Kolyvanos Naumann, U1
Käser, L1
Vetter, W1
Rutz, GM1
Williams, DA1
Goss, CH2
Hayes, D1
Newman, L1
O'Rourke, A1
Wagener, J1
Moss, R1
Hendeles, L2
Orenstein, D1
Ahrens, R1
Oermann, CM1
Aitken, ML1
Mahl, TC1
Young, KR1
Dunitz, J1
Murray, FT2
Sheptulin, AA1
Limauro, S1
Blake, K1
Casey, S1
Quittner, AL1
Bentley, T1
Sarles, J1
Iakovenko, AV1
Agafonova, NA1
Iakovenko, EP1
Garvey, MS1
Zawie, DA1
Westermarck, E1
Sandholm, M1
Worning, H1
Dockter, G1
Sitzmann, FC1
Götze, H1
Goff, JS1
Jansen, W1
Vulinec, M1
Pap, A1
Varró, V1
Isaksson, G1
Lundquist, I1
Akesson, B1
Ihse, I1
Graham, DY3
Dutta, SK4
Rubin, J1
Harvey, J1
Tilley, DK1
Hafkenscheid, JC1
Hessels, M1
Jansen, JB1
Lamers, CB2
Simpson, JW1
Doxey, DL1
Durie, PR5
Lee, L1
Hill, R1
Forstner, GG4
DiMagno, EP2
Fredrikzon, B1
Hernell, O1
Bläckberg, L1
Stafford, RJ1
Grand, RJ2
Grözinger, KH1
Hill, RE1
Davidson, GP1
Mischler, EH1
Parrell, S1
Farrell, PM1
Odell, GB1
Bell, L1
Linton, W1
Corey, ML1
Hoppe-Seyler, P1
Gerok, W1
Bozkurt, T1
Braun, U1
Leferink, S1
Gilly, G1
Lux, G1
Gröger, G1
Adler, G2
Mundlos, S2
Kühnelt, P2
Dreyer, E1
Meyer, JH4
Hlinka, M1
Jehn, D2
Gu, YG3
Dodge, JA3
Macpherson, C1
Doty, JE2
Kropp, J2
Knapp, FF2
Weyenberg, A1
McPherson, DW2
Ambrose, KR2
Callahan, AP2
von Bergmann, K1
Biersack, HJ2
Bovo, P1
Cataudella, G1
Di Francesco, V1
Vaona, B1
Filippini, M1
Marcori, M1
Montesi, G1
Rigo, L1
Frulloni, L1
Brunori, MP1
Jones, NL1
Hofley, PM1
Zylberberg, P2
Delchier, JC2
Thomson, M1
Clague, A1
Cleghorn, GJ1
Shepherd, RW1
Kraisinger, M1
Hochhaus, G1
Stecenko, A1
Bowser, E1
Rauws, EA1
Hoek, FJ1
Tytgat, GN1
Ramakrishna, J1
Henry, JP1
Steinberg, WM1
Vantini, I2
Fioretta, A1
Bonfante, F1
Brentegnani, MT1
Benini, L2
Castellani, G1
Holtmann, G1
Guarner, L1
Rodríguez, R1
Guarner, F1
Malagelada, JR1
Lambert, CR1
Kirsch, G1
Nakamura, T2
Takebe, K1
Kudoh, K1
Ishii, M1
Imamura, K2
Kikuchi, H2
Kasai, F1
Tandoh, Y2
Yamada, N2
Arai, Y1
O'Hare, MM1
McMaster, C1
Löser, C2
Fölsch, UR2
Regele, S1
Henker, J1
Münch, R2
Barbier, Y1
Stern, M1
Lancellotti, L1
Cabrini, G1
Zanolla, L1
Mastella, G1
Delhaye, M1
Meuris, S1
Gohimont, AC1
Buedts, K1
Cremer, M1
Wøjdemann, M2
Olsen, O2
Larsen, S2
Sternby, B2
Rehfeld, JF1
Suzuki, A2
Mizumoto, A2
Sarr, MG2
Opekun, AR1
Sutton, FM1
Swart, GR1
Baartman, EA1
Wattimena, JL1
Rietveld, T1
Overbeek, SE1
van den Berg, JW1
Montalto, G1
D'Angelo, P1
Lo Casto, A1
Carroccio, A1
Soresi, M1
Midiri, M1
Malizia, R1
Scafidi, V1
Stevens, JC1
Maguiness, KM1
Hollingsworth, J1
Heilman, DK1
Chong, SK1
Terada, A1
Watanabe, T1
Kaji, A1
Suda, T1
Browning, T1
Rerknimitr, R1
DiMango, EP1
Carrère, J1
Guy-Crotte, O1
Gaia, E1
Figarella, C1
Hershkovits, BS1
Dagan, J1
Freier, S1
Nassir, F1
Davidson, NO1
Augarten, A1
Shmilovich, H1
Doolman, R1
Aviram, M1
Akons, H1
Ben Tur, L1
Blau, H1
Rivlin, J1
Sela, BA1
Szeinberg, A1
Yahav, Y1
Tchoua, U1
Ito, M1
Okamoto, M1
Tojo, H1
Lark, RK1
Lester, GE1
Ontjes, DA1
Blackwood, AD1
Hollis, BW1
Hensler, MM1
Aris, RM1
Adamama-Moraitou, KK1
Rallis, TS1
Prassinos, NN1
Papasteriadis, A1
Roubies, N1
Bardoń, A1
Nowakowska, A1
Bozkowa, K1
Richter, T1
Müller, D1
Senger, H1
Beyreiss, K1
Morrison, G1
Morrison, JM1
Redmond, AO1
Byers, CA1
McCracken, KJ1
Guilford, SA1
Bowden, MW1
al-Modaris, FI1
Power, MJ1
McConnell, JG1
Taylor, IC1
Armstrong, E1
Buchanan, KD1
Muench, R1
Ammann, R1
Lechowski, R1
Pisarski, J1
Gosławski, J1
Lenarcik, M1
Vidon, N1
Saint-Marc Girardin, MF1
Soule, JC1
Moulin, C1
Huchet, B1
Moreau, J2
Bouisson, M2
Balas, D1
Ravaud, A1
Stupnik, S1
Buscail, L1
Vaysse, N1
Ribet, A2
Murphy, MS1
Eastham, EJ1
Nelson, R1
Aynsley-Green, A1
Williams, J1
MacDonald, A1
Weller, PH1
Fields, J1
Pandov, H1
Andersen, JR1
Bendtsen, F1
Ovesen, L1
Pedersen, NT1
Rune, SJ1
Tage-Jensen, U1
Ligumsky, M1
Granot, E1
Branski, D1
Stankiewicz, H1
Goldstein, R1
Braga, M1
Zerbi, A1
Dal Cin, S1
De Franchis, R1
Malesci, A1
Di Carlo, V1
Kehl, O1
Bühler, H1
Pei, P1
Ammann, RW1
Abello, J1
Pascaud, X1
Simoes-Nunes, C1
Cuber, JC1
Junien, JL1
Rozé, C1
Saloniemi, H1
Kalima, TV1
Rahko, T1
Roberts, IM1
Morrow, JD1
Griffin, SM1
Alderson, D1
Farndon, JR1
Gregar, I1
Kojecký, Z1
Matlocha, Z1
Brugge, WR1
Goldberg, HJ1
Burke, CA1
Depping, BJ1
Hubbard, VS2
Appler, M1
Zerega, J1
Lerner, S1
Gosselin, M1
Saint-Marc-Girardin, MF1
Pignal, F1
Bommelaer, G1
Gerber, B1
Siegmund, E1
Dummler, W1
Gerber, S1
Moreau, H1
Sauniere, JF1
Gargouri, Y1
Pieroni, G1
Verger, R1
Sarles, H1
De Clercq, R1
Lembcke, B1
Göke, B1
Freise, J1
Horstkotte, H1
Weizman, Z1
Kopelman, HR1
Vesely, SM1
Abrams, CK1
Hamosh, M1
Hamosh, P1
Cavallini, G1
Piubello, W1
Brocco, G1
Micciolo, R1
Chech, G1
Angelini, G1
Riela, A1
Dalle Molle, L1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Gallstone Characteristics for the Severity of Acute Gallstone Pancreatitis[NCT05498961]301 participants (Actual)Observational2022-08-10Completed
Immediate Endoscopic Necrosectomy vs. On-demand Necroectomy in Infected Walled-off Pancreatic Necrosis[NCT05530772]50 participants (Anticipated)Interventional2022-09-12Recruiting
Impact of Exocrine Pancreatic Insufficiency Associated With Acute Pancreatitis and Pancreatic Enzyme Replacement Therapy on Gut Microbiota, Immunological Changes and Quality of Life[NCT05480241]84 participants (Anticipated)Interventional2022-05-01Recruiting
Proton Pump Inhibitors (PPI) and Fat Absorption in Subjects With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)[NCT03551691]Phase 219 participants (Actual)Interventional2018-08-07Completed
A Randomized, Double-blind, Multicenter, Two-period Crossover Study to Assess the Efficacy and Tolerability of NM-BL (Burlulipase) in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis[NCT01710644]Phase 1/Phase 235 participants (Actual)Interventional2013-05-31Completed
The Incidence of Pancreatic Exocrine Insufficiency and the Benefits of Pancreatic Enzyme Supplementation in Critically Ill Adult Patients[NCT01753024]362 participants (Actual)Observational [Patient Registry]2012-01-31Completed
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Crossover Study to Evaluate the Effectiveness and Safety of PANCRECARB® MS-16 (Pancrelipase) in Reducing Steatorrhea in Children and Adults With Cystic Fibrosis[NCT00432861]Phase 329 participants (Actual)Interventional2007-01-31Completed
A Phase III Randomized Double Blind Placebo Controlled Trial of CM-AT in Children With Autism[NCT00881452]Phase 3182 participants (Actual)Interventional2009-05-31Completed
Pancreatic Enzyme Replacement Therapy (PERT) for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer[NCT02985801]Phase 1/Phase 216 participants (Actual)Interventional2016-12-31Terminated (stopped due to Study was terminated due to difficulty in recruiting subjects.)
Enzyme Substitution in Exocrine Pancreatic Insufficiency; Self Administration Against a Fixed Dose Regimen[NCT01430234]Phase 410 participants (Actual)Interventional2011-10-31Completed
A Pilot Study Evaluating Single, High-dose Pharmacokinetics/Pharmacodynamics of Vitamin D3 in CF[NCT03734744]6 participants (Actual)Interventional2019-06-17Terminated (stopped due to Clinical research currently on hold)
Double-blind Randomized Study to Determine the Efficacy of Intramuscular Vitamin D3 Supplementation in Tropical Calcific Pancreatitis[NCT00956839]Phase 440 participants (Actual)Interventional2009-07-31Completed
Phase II Study: LYM-X-SORB™, an Organized Lipid Matrix: Fatty Acids and Choline in CF[NCT00406536]Phase 2110 participants (Actual)Interventional2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Percentage of Patients With Serum 25 Hydroxy Vitamin D3 > 30 ng/ml

Percentage of patients in each group with serum 25 hydroxy vitamin D >30 ng/ml (NCT00956839)
Timeframe: 6 months post intervention

Interventionpercentage of patients (Number)
IM Vitamin D3 3,00,000 Units85
IM Vitamin D3 6,00,000 Units29
Oral Vitamin D30

Serum Total Calcium

Serum total calcium (mg/dL) at time points 0, 1, 3 and 6 months (NCT00956839)
Timeframe: 0, 1, 3, 6 months post intervention

,,
Interventionmg/dL (Mean)
baseline1 month3 months6 months
IM Vitamin D3 3,00,000 Units9.209.289.409.40
IM Vitamin D3 6,00,000 Units9.569.529.449.40
Oral Vitamin D39.249.289.409.28

Reviews

28 reviews available for 1-anilino-8-naphthalenesulfonate and Pancreatic Insufficiency

ArticleYear
Acute pancreatitis.
    Lancet (London, England), 2020, 09-05, Volume: 396, Issue:10252

    Topics: Amylases; Anti-Bacterial Agents; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy; D

2020
Acute pancreatitis.
    Lancet (London, England), 2020, 09-05, Volume: 396, Issue:10252

    Topics: Amylases; Anti-Bacterial Agents; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy; D

2020
Acute pancreatitis.
    Lancet (London, England), 2020, 09-05, Volume: 396, Issue:10252

    Topics: Amylases; Anti-Bacterial Agents; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy; D

2020
Acute pancreatitis.
    Lancet (London, England), 2020, 09-05, Volume: 396, Issue:10252

    Topics: Amylases; Anti-Bacterial Agents; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy; D

2020
The Role of Sphere Size in the Context of Pancreatin Therapy for Exocrine Pancreatic Insufficiency: A Systematic Review.
    Journal of gastrointestinal and liver diseases : JGLD, 2021, Mar-12, Volume: 30, Issue:1

    Topics: Duodenum; Exocrine Pancreatic Insufficiency; Gastric Emptying; Humans; Lipase; Pancreatin

2021
A primer on exocrine pancreatic insufficiency, fat malabsorption, and fatty acid abnormalities.
    The American journal of managed care, 2017, Volume: 23, Issue:12 Suppl

    Topics: Age Factors; Age of Onset; Cystic Fibrosis; Dietary Fats; Digestive System Surgical Procedures; Enzy

2017
Options for addressing exocrine pancreatic insufficiency in patients receiving enteral nutrition supplementation.
    The American journal of managed care, 2017, Volume: 23, Issue:12 Suppl

    Topics: Dietary Fats; Energy Intake; Enteral Nutrition; Enzyme Replacement Therapy; Exocrine Pancreatic Insu

2017
Maldigestion from pancreatic exocrine insufficiency.
    Journal of gastroenterology and hepatology, 2013, Volume: 28 Suppl 4

    Topics: Administration, Oral; Atherosclerosis; Breath Tests; Cardiovascular Diseases; Diet, Fat-Restricted;

2013
[Cholestasis and pancreatic insufficiency: how to start treatment?].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2014, Issue:8

    Topics: Cholestasis; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Replacement Therapy; Ex

2014
Challenges and Updates in the Management of Exocrine Pancreatic Insufficiency.
    Pancreas, 2016, Volume: 45, Issue:1

    Topics: Diet, Fat-Restricted; Dietary Fats; Enzyme Replacement Therapy; Exocrine Pancreatic Insufficiency; H

2016
Pancreatic exocrine insufficiency: diagnosis and treatment.
    Journal of gastroenterology and hepatology, 2011, Volume: 26 Suppl 2

    Topics: Breath Tests; Enzyme Replacement Therapy; Exocrine Pancreatic Insufficiency; Feeding Behavior; Human

2011
Pancreatic enzyme supplementation.
    Current opinion in pediatrics, 2011, Volume: 23, Issue:5

    Topics: Amylases; Cystic Fibrosis; Drug Approval; Enzyme Replacement Therapy; Exocrine Pancreatic Insufficie

2011
Lipase supplementation therapy: standards, alternatives, and perspectives.
    Pancreas, 2003, Volume: 26, Issue:1

    Topics: Animals; Bacteria; Cattle; Celiac Disease; Chronic Disease; Exocrine Pancreatic Insufficiency; Fats;

2003
[Chronic pancreatitis. Main symptoms: chronic abdominal pain, weight loss in steatorrhea, secondary diabetes mellitus].
    Praxis, 2005, Jul-27, Volume: 94, Issue:30-31

    Topics: Abdominal Pain; Adult; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Diabetes Me

2005
[Modern principles of the diagnostics and enzyme therapy of exocrine pancreatic insufficiency].
    Klinicheskaia meditsina, 2006, Volume: 84, Issue:8

    Topics: Breath Tests; Exocrine Pancreatic Insufficiency; Humans; Lipase; Trypsin

2006
Pancreatic enzyme therapy for pancreatic exocrine insufficiency.
    Current gastroenterology reports, 2007, Volume: 9, Issue:2

    Topics: Exocrine Pancreatic Insufficiency; Feeding Behavior; Gastric Emptying; Humans; Lipase; Microspheres;

2007
Feline pancreatic disease.
    The Veterinary clinics of North America. Small animal practice, 1984, Volume: 14, Issue:6

    Topics: Amylases; Amyloidosis; Animals; Bilirubin; Blood Glucose; Cat Diseases; Cats; Clinical Enzyme Tests;

1984
[Examination of pancreatic function in children with special reference to the PABA-test (author's transl)].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1980, Volume: 128, Issue:12

    Topics: 4-Aminobenzoic Acid; Acute Disease; Aminobenzoates; Amylases; Child; Child, Preschool; Chronic Disea

1980
[New facts on the diagnosis of exocrine pancreatic insufficiency in carnivora].
    Tierarztliche Praxis, 1980, Volume: 8, Issue:1

    Topics: 4-Aminobenzoic Acid; Alkaline Phosphatase; Amylases; Animals; Atrophy; Carnivora; Chymotrypsin; Dog

1980
Hereditary disease of the exocrine pancreas.
    Clinics in gastroenterology, 1982, Volume: 11, Issue:1

    Topics: Adolescent; Adult; alpha 1-Antitrypsin Deficiency; Child; Child, Preschool; Cystic Fibrosis; Exocrin

1982
Fate of pancreatic enzymes in the human intestinal lumen in health and pancreatic insufficiency.
    Digestion, 1993, Volume: 54 Suppl 2

    Topics: Amylases; Exocrine Pancreatic Insufficiency; Gastric Emptying; Humans; Intestinal Mucosa; Lipase; Pa

1993
New methods for assessment of enzyme activity: do they help to optimize enzyme treatment?
    Digestion, 1993, Volume: 54 Suppl 2

    Topics: Amylases; Breath Tests; Celiac Disease; Cholesterol Esters; Duodenum; Exocrine Pancreatic Insufficie

1993
Colonic strictures in cystic fibrosis.
    Journal of the Royal Society of Medicine, 1995, Volume: 88 Suppl 25

    Topics: Colonic Diseases; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Humans; Intestinal Diseases; I

1995
[Treatment of exocrine pancreatic insufficiency: what gastroprotection do pancreatic enzymes provide?].
    Gastroenterologie clinique et biologique, 1993, Volume: 17, Issue:11

    Topics: Adolescent; Adult; Antacids; Capsules; Child; Chronic Disease; Cystic Fibrosis; Enzymes, Immobilized

1993
Clinical pharmacology of pancreatic enzymes in patients with cystic fibrosis and in vitro performance of microencapsulated formulations.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:2

    Topics: Adolescent; Chemistry, Pharmaceutical; Child; Child, Preschool; Cystic Fibrosis; Exocrine Pancreatic

1994
[Therapy with pancreatic enzyme preparations].
    Medizinische Monatsschrift fur Pharmazeuten, 1993, Volume: 16, Issue:2

    Topics: Chronic Disease; Enzyme Therapy; Exocrine Pancreatic Insufficiency; Humans; Lipase; Pancreatic Extra

1993
[Differential therapy of exocrine pancreatic insufficiency--current aspects and future prospects of substitution therapy with pancreatic enzymes].
    Zeitschrift fur Gastroenterologie, 1995, Volume: 33, Issue:12

    Topics: Exocrine Pancreatic Insufficiency; Forecasting; Humans; Lipase; Pancreatic Extracts; Pancreatic Func

1995
Pancreatic enzymes: secretion and luminal nutrient digestion in health and disease.
    Journal of clinical gastroenterology, 1999, Volume: 28, Issue:1

    Topics: Amylases; Chronic Disease; Digestion; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Ga

1999
[Clinical and pharmacological aspects of pancreatic enzyme substitution therapy].
    Leber, Magen, Darm, 1991, Volume: 21, Issue:2

    Topics: Alcoholism; Amylases; Celiac Disease; Endopeptidases; Exocrine Pancreatic Insufficiency; Histamine H

1991
Enzyme therapy for malabsorption in exocrine pancreatic insufficiency.
    Pancreas, 1989, Volume: 4, Issue:4

    Topics: Dietary Fats; Enzyme Therapy; Enzymes; Exocrine Pancreatic Insufficiency; Humans; Lipase; Malabsorpt

1989
Pancreatic enzyme replacement therapy.
    The American journal of the medical sciences, 1989, Volume: 298, Issue:5

    Topics: Adult; Capsules; Celiac Disease; Child; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Humans;

1989

Trials

32 trials available for 1-anilino-8-naphthalenesulfonate and Pancreatic Insufficiency

ArticleYear
Study of the gastrointestinal bioavailability of a pancreatic extract product (Zenpep) in chronic pancreatitis patients with exocrine pancreatic insufficiency.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2020, Volume: 20, Issue:6

    Topics: Adult; Aged; Amylases; Biological Availability; Cholecystokinin; Chymotrypsin; Cross-Over Studies; D

2020
The effect of oral pancreatic enzyme supplementation on the course and outcome of acute pancreatitis: a randomized, double-blind parallel-group study.
    JOP : Journal of the pancreas, 2014, Mar-10, Volume: 15, Issue:2

    Topics: Abdominal Pain; Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Amylases; APACH

2014
Malabsorption blood test: Assessing fat absorption in patients with cystic fibrosis and pancreatic insufficiency.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:8

    Topics: Adolescent; Adult; Child; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Fatty Acids; Female; H

2015
Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial.
    The Journal of pediatrics, 2016, Volume: 176

    Topics: Adolescent; Child; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Exocrine Pancreatic Ins

2016
International phase III trial of liprotamase efficacy and safety in pancreatic-insufficient cystic fibrosis patients.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Amylases; Child; Cystic Fibrosis; Double-Blind Method; Enzyme Replacement Therapy

2011
Liprotamase long-term safety and support of nutritional status in pancreatic-insufficient cystic fibrosis.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Amylases; Child; Cystic Fibrosis; Drug Administration Schedule; Enzyme Replacemen

2012
Exogenous pancreatic-like enzymes are recovered in the gut and improve growth of exocrine pancreatic insufficient pigs.
    Journal of animal science, 2012, Volume: 90 Suppl 4

    Topics: Amylases; Animals; Body Weight; Dose-Response Relationship, Drug; Exocrine Pancreatic Insufficiency;

2012
Behavioral changes in response to feeding pancreatic-like enzymes to exocrine pancreatic insufficiency pigs.
    Journal of animal science, 2012, Volume: 90 Suppl 4

    Topics: Amylases; Animals; Aspergillus; Burkholderia cepacia; Cross-Over Studies; Exocrine Pancreatic Insuff

2012
Ultrase MT12 and Ultrase MT20 in the treatment of exocrine pancreatic insufficiency in cystic fibrosis: safety and efficacy.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20, Issue:11-12

    Topics: Adolescent; Adult; Aged; Child; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Exocrine P

2004
Safety and preliminary clinical activity of a novel pancreatic enzyme preparation in pancreatic insufficient cystic fibrosis patients.
    Pancreas, 2006, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Amylases; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Female; Humans; Lip

2006
Study of a novel pancreatic enzyme replacement therapy in pancreatic insufficient subjects with cystic fibrosis.
    The Journal of pediatrics, 2006, Volume: 149, Issue:5

    Topics: Adolescent; Adult; Amylases; Analysis of Variance; Blood Glucose; Child; Cystic Fibrosis; Dose-Respo

2006
Proteolytic inactivation of lipase as a possible cause of the uneven results obtained with enzyme substitution in pancreatic insufficiency.
    Hepato-gastroenterology, 1984, Volume: 31, Issue:1

    Topics: Amylases; Celiac Disease; Chronic Disease; Clinical Trials as Topic; Exocrine Pancreatic Insufficien

1984
Comparative evaluation of the therapeutic efficacy of a pH-sensitive enteric coated pancreatic enzyme preparation with conventional pancreatic enzyme therapy in the treatment of exocrine pancreatic insufficiency.
    Gastroenterology, 1983, Volume: 84, Issue:3

    Topics: Adult; Dietary Fats; Duodenum; Evaluation Studies as Topic; Exocrine Pancreatic Insufficiency; Feces

1983
The pH-sensitive enteric-coated pancreatic enzyme preparations: an evaluation of therapeutic efficacy in adult patients with pancreatic insufficiency.
    Journal of clinical gastroenterology, 1983, Volume: 5, Issue:1

    Topics: Adult; Evaluation Studies as Topic; Exocrine Pancreatic Insufficiency; Humans; Hydrogen-Ion Concentr

1983
Comparison of effectiveness of pancreatic enzyme preparations in cystic fibrosis.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:12

    Topics: Adolescent; Child; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Humans; Lipase; Malabsorption

1982
Effect of cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis.
    Gut, 1980, Volume: 21, Issue:9

    Topics: Adolescent; Bicarbonates; Celiac Disease; Child; Cimetidine; Cystic Fibrosis; Dietary Fats; Drug The

1980
Comparative in vitro and in vivo studies of enteric-coated pancrelipase preparations for pancreatic insufficiency.
    Journal of pediatric gastroenterology and nutrition, 1993, Volume: 17, Issue:4

    Topics: Amino Acid Sequence; Child; Exocrine Pancreatic Insufficiency; Humans; Intestinal Absorption; Lipase

1993
Comparative effects of adjuvant cimetidine and omeprazole during pancreatic enzyme replacement therapy.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:5

    Topics: Adult; Aged; Celiac Disease; Cimetidine; Double-Blind Method; Exocrine Pancreatic Insufficiency; Fem

1994
Fate of oral enzymes in pancreatic insufficiency.
    Gut, 1993, Volume: 34, Issue:5

    Topics: Celiac Disease; Delayed-Action Preparations; Duodenum; Exocrine Pancreatic Insufficiency; Feces; Fem

1993
Indirect parameters of pancreatic function in cystic fibrosis (CF) during a controlled double-blind trial of pancreatic supplementation.
    Journal of pediatric gastroenterology and nutrition, 1996, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Chymotrypsin; Cystic Fibrosis; Double-Blind Method; Exoc

1996
High- versus low-lipase acid-resistant enzyme preparations in cystic fibrosis: a crossover randomized clinical trial.
    Journal of pediatric gastroenterology and nutrition, 1996, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Child; Cross-Over Studies; Cystic Fibrosis; Dietary Fats; Exocrine Pancreatic Ins

1996
Comparative evaluation of a high lipase pancreatic enzyme preparation and a standard pancreatic supplement for treating exocrine pancreatic insufficiency in chronic pancreatitis.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:7

    Topics: Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Exocrine Pancreatic Ins

1996
Lack of dose-response with Pancrease MT for the treatment of exocrine pancreatic insufficiency in adults.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:5

    Topics: Adult; Celiac Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Exocrine Pancreatic Ins

1997
Cephalic phase of lipolysis is impaired in pancreatic insufficiency: role of gastric lipase.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:2

    Topics: Adult; Biopsy; Chronic Disease; Endoscopy, Digestive System; Enteral Nutrition; Exocrine Pancreatic

2000
Comparison between a standard pancreatic supplement and a high enzyme preparation in cystic fibrosis.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Chemistry, Pharmaceutical; Child; Child, Preschool; Cystic Fibrosis; Dose-Respons

1992
[Effect of pellet size of a pancreas enzyme preparation on duodenal lipolytic activity].
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29, Issue:9

    Topics: Adult; Breath Tests; Double-Blind Method; Duodenum; Exocrine Pancreatic Insufficiency; Humans; Lipas

1991
Fate of orally ingested enzymes in pancreatic insufficiency: comparison of two pancreatic enzyme preparations.
    Alimentary pharmacology & therapeutics, 1991, Volume: 5, Issue:4

    Topics: Adult; Bile Acids and Salts; Celiac Disease; Chymotrypsin; Exocrine Pancreatic Insufficiency; Feces;

1991
Two enteric coated microspheres in cystic fibrosis.
    Archives of disease in childhood, 1990, Volume: 65, Issue:6

    Topics: Adolescent; Body Weight; Capsules; Child; Child, Preschool; Cystic Fibrosis; Dietary Fats; Exocrine

1990
Maximal effective dose of cerulein in the secretin-cerulein test.
    Digestion, 1988, Volume: 39, Issue:4

    Topics: Adult; Bicarbonates; Ceruletide; Chronic Disease; Chymotrypsin; Clinical Trials as Topic; Exocrine P

1988
Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:10

    Topics: Adult; Cystic Fibrosis; Delayed-Action Preparations; Drug Evaluation; Duodenum; Exocrine Pancreatic

1988
[Comparison of fungal lipase and pancreatic lipase in exocrine pancreatic insufficiency in man. Study of their in vitro properties and intraduodenal bioavailability].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:11

    Topics: Bile Acids and Salts; Biological Availability; Colipases; Duodenum; Eating; Exocrine Pancreatic Insu

1988
Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage?
    Zeitschrift fur Gastroenterologie, 1986, Volume: 24, Issue:12

    Topics: Celiac Disease; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; Ex

1986

Other Studies

126 other studies available for 1-anilino-8-naphthalenesulfonate and Pancreatic Insufficiency

ArticleYear
Correlates of Pancreatic Enzyme Replacement Therapy Intake in Adults with Cystic Fibrosis: Results of a Cross-Sectional Study.
    Nutrients, 2022, Mar-22, Volume: 14, Issue:7

    Topics: Adult; Cross-Sectional Studies; Cystic Fibrosis; Enzyme Replacement Therapy; Exocrine Pancreatic Ins

2022
Pancreatic enzyme treatment in chronic pancreatitis: Quality of management and adherence to guidelines-A cross-sectional observational study.
    United European gastroenterology journal, 2022, Volume: 10, Issue:8

    Topics: Enzyme Replacement Therapy; Exocrine Pancreatic Insufficiency; Humans; Lipase; Pancreatic Elastase;

2022
An Unusual Cause of Diarrhea in Young Adulthood.
    Gastroenterology, 2023, Volume: 164, Issue:6

    Topics: Adult; Diarrhea; Exocrine Pancreatic Insufficiency; Humans; Lipase; Pancreas, Exocrine; Young Adult

2023
Validation of an omega-3 substrate challenge absorption test as an indicator of global fat lipolysis.
    PloS one, 2023, Volume: 18, Issue:5

    Topics: Animals; Exocrine Pancreatic Insufficiency; Fatty Acids, Omega-3; Humans; Intestinal Absorption; Lip

2023
Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia.
    Gastroenterology, 2020, Volume: 159, Issue:1

    Topics: Adult; Aged; Amylases; Betacoronavirus; China; Coronavirus Infections; COVID-19; Exocrine Pancreatic

2020
Differences in In Vitro Properties of Pancreatin Preparations for Pancreatic Exocrine Insufficiency as Marketed in Russia and CIS.
    Drugs in R&D, 2020, Volume: 20, Issue:4

    Topics: Commonwealth of Independent States; Drug Liberation; Exocrine Pancreatic Insufficiency; Gastrointest

2020
Fecal elastase levels in children diagnosed with functional abdominal pain-not otherwise specified.
    The Turkish journal of pediatrics, 2021, Volume: 63, Issue:1

    Topics: Abdominal Pain; Child; Exocrine Pancreatic Insufficiency; Feces; Humans; Lipase; Pancreatic Elastase

2021
Lipase elevation and type 1 diabetes mellitus related to immune checkpoint inhibitor therapy - A multicentre study of 90 patients from the German Dermatooncology Group.
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 149

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Exocrine Pancr

2021
Difference in Performance of EPI Pigs Fed Either Lipase-Predigested or Creon®-Supplemented Semielemental Diet.
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Astrocytes; Body Composition; Bone and Bones; Diet; Enzyme Replacement Therapy; Exocrine Pa

2021
Bile salt stimulated lipase: Inhibition by phospholipids and relief by phospholipase A
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:6

    Topics: Cystic Fibrosis; Dietary Fats; Exocrine Pancreatic Insufficiency; Humans; Lipase; Magnetic Resonance

2017
Exocrine pancreatic insufficiency is common in people living with HIV on effective antiretroviral therapy.
    Infectious diseases (London, England), 2018, Volume: 50, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; Exocrine Pancreatic Insufficiency; Feces; Female; HIV

2018
Autoimmune pancreatitis after nivolumab anti-programmed death receptor-1 treatment.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 104

    Topics: Antineoplastic Agents, Immunological; Autoimmune Diseases; Biomarkers; Diffusion Magnetic Resonance

2018
Russian consensus on exo- and endocrine pancreatic insufficiency after surgical treatment.
    Terapevticheskii arkhiv, 2018, Aug-27, Volume: 90, Issue:8

    Topics: Blood Glucose; Consensus; Exocrine Pancreatic Insufficiency; Feces; Glycated Hemoglobin; Hormone Rep

2018
Characterization of all the lipolytic activities in pancreatin and comparison with porcine and human pancreatic juices.
    Biochimie, 2020, Volume: 169

    Topics: Amino Acid Sequence; Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Enzyme Assays; Enzyme S

2020
Biomarkers of exocrine pancreatic injury in 2 rat acute pancreatitis models.
    Toxicologic pathology, 2014, Volume: 42, Issue:1

    Topics: Acute Disease; Alkenes; Amylases; Animals; Biomarkers; Ceruletide; Disease Models, Animal; Dose-Resp

2014
Pancreatic enzyme replacement therapy dosing and nutritional outcomes in children with cystic fibrosis.
    The Journal of pediatrics, 2014, Volume: 164, Issue:5

    Topics: Adolescent; Body Mass Index; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule;

2014
An interfacial and comparative in vitro study of gastrointestinal lipases and Yarrowia lipolytica LIP2 lipase, a candidate for enzyme replacement therapy.
    Biochimie, 2014, Volume: 102

    Topics: Animals; Bile Acids and Salts; Dogs; Enzyme Replacement Therapy; Enzyme Stability; Exocrine Pancreat

2014
Extended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate diet.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Amylases; Animals; Apoptosis; Autophagy; Diet, High-Fat; Dietary Carbohydrates; Drug Administration

2014
A piglet with surgically induced exocrine pancreatic insufficiency as an animal model of newborns to study fat digestion.
    The British journal of nutrition, 2014, Dec-28, Volume: 112, Issue:12

    Topics: Animals; Body Weight; Dietary Fats, Unsaturated; Digestion; Disease Models, Animal; Exocrine Pancrea

2014
Gastrointestinal symptoms before and after total pancreatectomy with islet autotransplantation: the role of pancreatic enzyme dosing and adherence.
    Pancreas, 2015, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Child, Preschool; Enzyme Replacement Therapy; Exocrin

2015
[The clinical application of 13C-breath tests in pancreatic diseases].
    Likars'ka sprava, 2014, Issue:11

    Topics: Adult; Aged; Amylases; Breath Tests; Carbohydrate Metabolism; Carbon Isotopes; Enzyme Replacement Th

2014
Monitoring changes in plasma levels of pancreatic and intestinal enzymes in a model of pancreatic exocrine insufficiency--induced by pancreatic duct-ligation--in young pigs.
    Advances in medical sciences, 2015, Volume: 60, Issue:1

    Topics: Amylases; Animals; Exocrine Pancreatic Insufficiency; Intestines; Ligation; Lipase; Pancreas; Pancre

2015
Pancreatic Enzyme Replacement Therapy and Coefficient of Fat Absorption in Children and Adolescents With Cystic Fibrosis.
    Journal of pediatric gastroenterology and nutrition, 2015, Volume: 61, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Cystic Fibrosis; Diet Records; Enzyme

2015
Yarrowia lipolytica Lipase 2 Is Stable and Highly Active in Test Meals and Increases Fat Absorption in an Animal Model of Pancreatic Exocrine Insufficiency.
    Gastroenterology, 2015, Volume: 149, Issue:7

    Topics: Administration, Oral; Animals; Carboxylic Ester Hydrolases; Disease Models, Animal; Dogs; Enzyme Rep

2015
Next Generation of Pancreatic Enzyme Replacement Therapy: Recombinant Microbial Enzymes and Finding the Perfect Lipase.
    Gastroenterology, 2015, Volume: 149, Issue:7

    Topics: Animals; Carboxylic Ester Hydrolases; Enzyme Replacement Therapy; Exocrine Pancreatic Insufficiency;

2015
Betaine Attenuates Alcohol-Induced Pancreatic Steatosis.
    Pancreas, 2016, Volume: 45, Issue:6

    Topics: Adiponectin; Amylases; Animals; Betaine; Blotting, Western; Cell Line, Tumor; Central Nervous System

2016
Pancreatic Lipase Immunoreactivity in Serum of Dogs with Diabetic Ketoacidosis.
    Journal of veterinary internal medicine, 2016, Volume: 30, Issue:4

    Topics: Animals; Diabetic Ketoacidosis; Dog Diseases; Dogs; Exocrine Pancreatic Insufficiency; Lipase; Pancr

2016
Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:11

    Topics: Amylases; Animal Feed; Animals; Bile Acids and Salts; Cloning, Molecular; Colorimetry; Drug Combinat

2016
Should we Investigate Gastroenterology Patients for Pancreatic Exocrine Insufficiency? A Dual Centre UK Study.
    Journal of gastrointestinal and liver diseases : JGLD, 2016, Volume: 25, Issue:3

    Topics: Biomarkers; Clinical Enzyme Tests; Comorbidity; England; Enzyme Replacement Therapy; Exocrine Pancre

2016
Exocrine pancreatic function in children with Alagille syndrome.
    Scientific reports, 2016, 10-17, Volume: 6

    Topics: Adolescent; Alagille Syndrome; Breath Tests; Child; Child, Preschool; Digestion; Exocrine Pancreatic

2016
Utility of Direct Pancreatic Function Testing in Children.
    Pancreas, 2017, Volume: 46, Issue:2

    Topics: Amylases; Child; Child, Preschool; Chymotrypsin; Enzyme Replacement Therapy; Exocrine Pancreatic Ins

2017
[Clinical features of different variants of excretory pancreatic insufficiency].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:2

    Topics: Asthenia; Diarrhea; Exocrine Pancreatic Insufficiency; Feces; Female; Humans; Lipase; Male; Middle A

2009
Properties of different pancreatin preparations used in pancreatic exocrine insufficiency.
    European journal of gastroenterology & hepatology, 2009, Volume: 21, Issue:9

    Topics: Amylases; Digestion; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Humans; Lipase; Mic

2009
Irreversible exocrine pancreatic insufficiency in alcoholic rats without chronic pancreatitis after alcohol withdrawal.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:11

    Topics: Alcoholism; Amylases; Animals; Blotting, Western; Central Nervous System Depressants; Cholecystokini

2010
A highly stable Yarrowia lipolytica lipase formulation for the treatment of pancreatic exocrine insufficiency.
    Biotechnology and applied biochemistry, 2010, Volume: 57, Issue:4

    Topics: Animals; Bile Acids and Salts; Candida; Chemistry, Pharmaceutical; Chymotrypsin; Enzyme Replacement

2010
Observational study of 14 cases of chronic pancreatitis in dogs.
    The Veterinary record, 2010, Dec-18, Volume: 167, Issue:25

    Topics: Abdominal Pain; Amylases; Animals; Biomarkers; Cholesterol; Clinical Enzyme Tests; Diabetes Complica

2010
A modified ¹³C-mixed triglyceride breath test detects moderate pancreatic exocrine insufficiency.
    Pancreas, 2011, Volume: 40, Issue:8

    Topics: Adult; Aged; Breath Tests; Caprylates; Carbon Isotopes; Exocrine Pancreatic Insufficiency; Female; G

2011
Variant of the Thermomyces lanuginosus lipase with improved kinetic stability: a candidate for enzyme replacement therapy.
    Biophysical chemistry, 2013, Volume: 172

    Topics: Ascomycota; Bile Acids and Salts; Calorimetry, Differential Scanning; Enzyme Replacement Therapy; Ex

2013
Evaluation of dietary fiber intake in Belgian children with cystic fibrosis: is there a link with gastrointestinal complaints?
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Belgium; Child; Child, Preschool; Constipation; Cystic Fibrosis; Diet Surveys; Di

2002
Exocrine pancreatic insufficiency as an end stage of pancreatitis in four dogs.
    The Journal of small animal practice, 2003, Volume: 44, Issue:7

    Topics: Amylases; Animals; Case-Control Studies; Chronic Disease; Disease Progression; Dog Diseases; Dogs; E

2003
The enzyme levels in blood are not affected by oral administration of a pancreatic enzyme preparation (Creon 10,000) in pancreas-insufficient pigs.
    Pancreas, 2004, Volume: 28, Issue:1

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Exocrine Pancreatic Insufficiency;

2004
Serum lipase after secretin stimulation detects mild pancreatic involvement in cystic fibrosis.
    Journal of pediatric gastroenterology and nutrition, 2004, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Child; Cystic Fibrosis; Exocrine Pancreatic Ins

2004
Exocrine pancreatic function after alcoholic or biliary acute pancreatitis.
    Pancreas, 2004, Volume: 28, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Amino Acids; Bicarbonates; Ceruletide; Cholelithiasis; Chymo

2004
Assessment of vitamin K deficiency in CF--how much sophistication is useful?
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2003, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Apolipoproteins E; Biomarkers; Bone Diseases, Metabolic; Case-Control Studies; Ch

2003
Pancreatic size in protein energy malnutrition: a predictor of nutritional recovery.
    European journal of clinical nutrition, 2005, Volume: 59, Issue:4

    Topics: Adolescent; Amylases; Child; Egypt; Exocrine Pancreatic Insufficiency; Female; Hemoglobins; Humans;

2005
Gastric lipase and pancreatic exocrine insufficiency.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:1

    Topics: Dietary Fats; Digestion; Exocrine Pancreatic Insufficiency; Humans; Lipase

2005
Pancreatitis among patients with cystic fibrosis: correlation with pancreatic status and genotype.
    Pediatrics, 2005, Volume: 115, Issue:4

    Topics: Adult; Amylases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Panc

2005
Does the pancreas really produce much more lipase than required for fat digestion?
    JOP : Journal of the pancreas, 2005, May-10, Volume: 6, Issue:3

    Topics: Animals; Dietary Fats; Digestion; Exocrine Pancreatic Insufficiency; Gastrointestinal Tract; Humans;

2005
Follow-up of exocrine pancreatic function in type-1 diabetes mellitus.
    Digestion, 2005, Volume: 72, Issue:2-3

    Topics: Adult; Amylases; Diabetes Mellitus, Type 1; Exocrine Pancreatic Insufficiency; Female; Follow-Up Stu

2005
Gastrointestinal lipolysis levels and potential use of gastric lipase in pancreatic insufficiency.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:7

    Topics: Exocrine Pancreatic Insufficiency; Humans; Lipase; Lipolysis

2005
Serum lipase activities and pancreatic lipase immunoreactivity concentrations in dogs with exocrine pancreatic insufficiency.
    American journal of veterinary research, 2006, Volume: 67, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Exocrine Pancreatic Insufficiency; Lipase; Pancreas; Statistics, Nonpar

2006
Meal patterns, dietary fat intake and pancreatic enzyme use in preadolescent children with cystic fibrosis.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 43, Issue:5

    Topics: Anthropometry; Child; Cystic Fibrosis; Dietary Fats; Energy Intake; Exocrine Pancreatic Insufficienc

2006
In vitro comparative study of three pancreatic enzyme preparations: dissolution profiles, active enzyme release and acid stability.
    Alimentary pharmacology & therapeutics, 2008, Feb-01, Volume: 27, Issue:3

    Topics: Amylases; Animals; Biological Availability; Chymotrypsin; Duodenum; Exocrine Pancreatic Insufficienc

2008
[Practical approaches to the treatment of chronic pancreatitis].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2007, Issue:6

    Topics: Abdominal Pain; Analgesics, Non-Narcotic; Enzyme Inhibitors; Exocrine Pancreatic Insufficiency; Hist

2007
Faecal hydrolase activity as determined by radial enzyme diffusion: a new method for detecting pancreatic dysfunction in the dog.
    Research in veterinary science, 1980, Volume: 28, Issue:3

    Topics: Agar; Amylases; Animals; Dog Diseases; Dogs; Exocrine Pancreatic Insufficiency; Feces; Gels; Hydrola

1980
The effect of enzyme substitution in patients with pancreatic insufficiency.
    Scandinavian journal of gastroenterology, 1980, Volume: 15, Issue:5

    Topics: Amylases; Dose-Response Relationship, Drug; Exocrine Pancreatic Insufficiency; Gastrectomy; Humans;

1980
[Exocrine pancreatic insufficiency (author's transl)].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1980, Volume: 128, Issue:12

    Topics: Amino Acid Metabolism, Inborn Errors; Amylases; Cystic Fibrosis; Enteropeptidase; Enzyme Therapy; Ex

1980
Pancreatic exocrine function testing.
    The Western journal of medicine, 1981, Volume: 135, Issue:5

    Topics: 4-Aminobenzoic Acid; Amylases; Carbon Radioisotopes; Exocrine Pancreatic Insufficiency; Fats; Feces;

1981
[Substitution of digestive enzymes in elderly patients].
    Die Medizinische Welt, 1982, Sep-17, Volume: 33, Issue:37

    Topics: Aged; Amylases; Digestive System Diseases; Double-Blind Method; Drug Therapy, Combination; Exocrine

1982
Effects of pectin and wheat bran on intraluminal pancreatic enzyme activities and on fat absorption as examined with the triolein breath test in patients with pancreatic insufficiency.
    Scandinavian journal of gastroenterology, 1984, Volume: 19, Issue:4

    Topics: Adult; Amylases; Breath Tests; Dietary Fats; Dietary Fiber; Exocrine Pancreatic Insufficiency; Femal

1984
Pancreatic enzyme replacement: the effect of antacids or cimetidine.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:6

    Topics: Adult; Aluminum Hydroxide; Antacids; Bicarbonates; Calcium Carbonate; Celiac Disease; Cimetidine; Ex

1982
Ins and outs of pancreatic enzymes and adjuvant therapies.
    Journal of pediatric gastroenterology and nutrition, 1984, Volume: 3 Suppl 1

    Topics: Bicarbonates; Celiac Disease; Enzyme Therapy; Exocrine Pancreatic Insufficiency; Humans; Lipase; Pan

1984
Serum trypsin, alpha-amylase and lipase during bombesin stimulation in normal subjects and patients with pancreatic insufficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1984, Jan-31, Volume: 136, Issue:2-3

    Topics: Adolescent; Adult; alpha-Amylases; Bombesin; Exocrine Pancreatic Insufficiency; Female; Humans; Infu

1984
Quantitative assessment of fat absorption and its diagnostic value in exocrine pancreatic insufficiency.
    Research in veterinary science, 1983, Volume: 35, Issue:2

    Topics: Animals; Dietary Fats; Dog Diseases; Dogs; Exocrine Pancreatic Insufficiency; Intestinal Absorption;

1983
Colipase and lipase secretion in childhood-onset pancreatic insufficiency. Delineation of patients with steatorrhea secondary to relative colipase deficiency.
    Gastroenterology, 1984, Volume: 86, Issue:1

    Topics: Adolescent; Adult; Celiac Disease; Child; Child, Preschool; Colipases; Cystic Fibrosis; Exocrine Pan

1984
Controversies in the treatment of exocrine pancreatic insufficiency.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:6

    Topics: Adult; Antacids; Celiac Disease; Child, Preschool; Cimetidine; Exocrine Pancreatic Insufficiency; Ga

1982
Lingual lipase. Its role in lipid digestion in infants with low birthweight and/or pancreatic insufficiency.
    Acta paediatrica Scandinavica. Supplement, 1982, Volume: 296

    Topics: Bile Acids and Salts; Cystic Fibrosis; Dietary Fats; Exocrine Pancreatic Insufficiency; Humans; Infa

1982
[Substitution of pancreatic enzymes].
    Die Medizinische Welt, 1982, Jan-15, Volume: 33, Issue:2

    Topics: Dosage Forms; Exocrine Pancreatic Insufficiency; Humans; Lipase; Pancreas; Tablets, Enteric-Coated

1982
Steatorrhea and pancreatic insufficiency in Shwachman syndrome.
    Gastroenterology, 1982, Volume: 83, Issue:1 Pt 1

    Topics: Adolescent; Aging; Agranulocytosis; Celiac Disease; Child; Child, Preschool; Cystic Fibrosis; Dietar

1982
Origin and development of exocrine pancreatic insufficiency in experimental renal failure.
    Gut, 1994, Volume: 35, Issue:3

    Topics: Amylases; Animals; DNA; Exocrine Pancreatic Insufficiency; Female; Kidney Failure, Chronic; Lipase;

1994
Comparison of pancreatic morphology and exocrine functional impairment in patients with chronic pancreatitis.
    Gut, 1994, Volume: 35, Issue:8

    Topics: Adult; Aged; Amylases; Bicarbonates; Chronic Disease; Exocrine Pancreatic Insufficiency; Female; Hum

1994
Preduodenal mechanisms compensate completely for absent pancreatic enzymes to stimulate gallbladder after meals.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:4

    Topics: Animals; Dietary Fats; Dogs; Duodenum; Eating; Exocrine Pancreatic Insufficiency; Female; Gallbladde

1995
Factors that affect the performance of lipase on fat digestion and absorption in a canine model of pancreatic insufficiency.
    Pancreas, 1994, Volume: 9, Issue:5

    Topics: Animals; Dietary Fats; Dietary Fiber; Digestion; Disease Models, Animal; Dogs; Duodenum; Exocrine Pa

1994
Evaluation of pancreatic lipase activity by simple urine analysis after oral administration of a new iodine-131-labeled triglyceride.
    European journal of nuclear medicine, 1994, Volume: 21, Issue:11

    Topics: Animals; Exocrine Pancreatic Insufficiency; Humans; Iodine Radioisotopes; Iodobenzenes; Lipase; Panc

1994
Intraluminal gastric pH in chronic pancreatitis.
    Gut, 1995, Volume: 36, Issue:2

    Topics: Bicarbonates; Chronic Disease; Circadian Rhythm; Digestion; Exocrine Pancreatic Insufficiency; Femal

1995
Effect of replenished lipase on postcibal absorption of fat in a canine model of pancreatic insufficiency.
    Pancreas, 1994, Volume: 9, Issue:4

    Topics: Animals; Dietary Fats; Disease Models, Animal; Dogs; Exocrine Pancreatic Insufficiency; Intestinal A

1994
Pathophysiology of the pancreatic defect in Johanson-Blizzard syndrome: a disorder of acinar development.
    The Journal of pediatrics, 1994, Volume: 125, Issue:3

    Topics: Case-Control Studies; Colipases; Consanguinity; Cystic Fibrosis; Exocrine Pancreatic Insufficiency;

1994
[Sense and nonsense in the treatment of exocrine pancreatic insufficiency].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, Aug-09, Volume: 83, Issue:32

    Topics: Cholecystokinin; Enzyme Therapy; Exocrine Pancreatic Insufficiency; Humans; Lipase; Pain Management;

1994
Gene therapy for exocrine pancreatic insufficiency.
    Gastroenterology, 1994, Volume: 106, Issue:6

    Topics: Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Gallbladder; Genetic Therapy; Humans; Lipase; Pa

1994
Pancreatic function tests in the rat model of chronic pancreatic insufficiency.
    Pancreas, 1993, Volume: 8, Issue:5

    Topics: Absorption; Animals; Chronic Disease; Chymotrypsin; Chymotrypsinogen; Dietary Fats; Disease Models,

1993
[In vitro study of a new pancreatic enzyme with high lipase content in enteric coated microtablets].
    La Clinica terapeutica, 1993, Volume: 142, Issue:5

    Topics: Biological Availability; Buffers; Chymotrypsin; Drug Evaluation; Duodenum; Exocrine Pancreatic Insuf

1993
Site-specific/stable radioiodination of 1,2-Pal-3-IPPA: an agent for the potential clinical evaluation of pancreatic insufficiency by urine analysis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:6

    Topics: Animals; Exocrine Pancreatic Insufficiency; Female; Iodine Radioisotopes; Iodobenzenes; Isotope Labe

1993
No negative feedback regulation between plasma CCK levels and luminal tryptic activities in patients with pancreatic insufficiency.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1995, Volume: 17, Issue:1

    Topics: Adult; Amylases; Cholecystokinin; Chronic Disease; Exocrine Pancreatic Insufficiency; Feedback; Food

1995
Stated versus actual lipase activity in pancreatic enzyme supplements: implications for clinical use.
    Journal of pediatric gastroenterology and nutrition, 1995, Volume: 21, Issue:1

    Topics: Dose-Response Relationship, Drug; Drug Industry; Exocrine Pancreatic Insufficiency; Food, Fortified;

1995
Deficient gastric lipase secretion in pancreatic insufficiency.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:3

    Topics: Adult; Case-Control Studies; Cholecystokinin; Exocrine Pancreatic Insufficiency; Female; Gastric Muc

1997
Bacterial lipase and high-fat diets in canine exocrine pancreatic insufficiency: a new therapy of steatorrhea?
    Gastroenterology, 1997, Volume: 112, Issue:6

    Topics: Animals; Bacterial Proteins; Celiac Disease; Dietary Fats; Disease Models, Animal; Dogs; Exocrine Pa

1997
Evaluation studies of the 13C-mixed triglyceride breath test in healthy controls and adult cystic fibrosis patients with exocrine pancreatic insufficiency.
    Digestion, 1997, Volume: 58, Issue:5

    Topics: Adult; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Carbon Isotopes; Case-Control Studies; C

1997
Serum and fecal pancreatic enzymes in beta-thalassemia major.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1997, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Amylases; beta-Thalassemia; Chymotrypsin; Exocrine Pancreatic Insufficiency; Fats

1997
Pancreatic enzyme supplementation in cystic fibrosis patients before and after fibrosing colonopathy.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 26, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Colon; Colonic Diseases; Cystic Fibrosis; Exocrine Pancreatic I

1998
Effects of high-lipase pancreatin on fecal fat, neutral sterol, bile acid, and short-chain fatty acid excretion in patients with pancreatic insufficiency resulting from chronic pancreatitis.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1998, Volume: 23, Issue:1

    Topics: Adult; Aged; Bile Acids and Salts; Chronic Disease; Exocrine Pancreatic Insufficiency; Fatty Acids;

1998
Exocrine pancreatic insufficiency in a cat.
    Australian veterinary journal, 1998, Volume: 76, Issue:2

    Topics: Animals; Blood Chemical Analysis; Cat Diseases; Cats; Exocrine Pancreatic Insufficiency; Female; Fol

1998
Effect of bacterial or porcine lipase with low- or high-fat diets on nutrient absorption in pancreatic-insufficient dogs.
    Gastroenterology, 1999, Volume: 116, Issue:2

    Topics: Animals; Bacteria; Bacterial Proteins; Celiac Disease; Chymotrypsin; Dietary Carbohydrates; Dietary

1999
Immunoreactive pancreatic Reg protein in sera from cystic fibrosis patients with and without pancreatic insufficiency.
    Gut, 1999, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Calcium-Binding Proteins; Child; Child, Preschool; Chromatography, Gel; Chymotryp

1999
Increased spontaneous chromosomal breakage in Shwachman syndrome.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 28, Issue:4

    Topics: Amylases; Bone Diseases, Developmental; Celiac Disease; Chromosome Breakage; Diarrhea; Exocrine Panc

1999
Intestinal Apo B48 secretion: a novel surrogate marker of pancreatic exocrine function.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Biomarkers; Celiac Disease; Chronic Di

1999
Serum lipase levels as a diagnostic marker in cystic fibrosis patients with normal or borderline sweat tests.
    Pediatric pulmonology, 2000, Volume: 30, Issue:4

    Topics: Adult; Child; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocr

2000
Increased intestinal phospholipase A(2) activity catalyzed by phospholipase B/lipase in WBN/Kob rats with pancreatic insufficiency.
    Biochimica et biophysica acta, 2000, Sep-27, Volume: 1487, Issue:2-3

    Topics: Age Factors; Amylases; Animals; Body Weight; Catalysis; Diet, Fat-Restricted; Dietary Fats; Digestiv

2000
Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Bone Density; Case-Control Studies; Cysti

2001
Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Bone Density; Case-Control Studies; Cysti

2001
Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Bone Density; Case-Control Studies; Cysti

2001
Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Bone Density; Case-Control Studies; Cysti

2001
Serum vitamin A concentration in dogs with experimentally induced exocrine pancreatic insufficiency.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2002, Volume: 72, Issue:3

    Topics: Amylases; Animals; Dietary Supplements; Dogs; Enzymes; Exocrine Pancreatic Insufficiency; Female; Li

2002
[Determination of the ribonuclease activity of the duodenal contents of children as a test in the differential diagnosis of cystic fibrosis and pancreatic exocrine insufficiency].
    Problemy medycyny wieku rozwojowego, 1979, Volume: 8

    Topics: Amylases; Child; Child, Preschool; Cystic Fibrosis; Diagnosis, Differential; Duodenum; Exocrine Panc

1979
[Determination of exocrine pancreatic function in childhood with the pancreozymin-secretin test].
    Kinderarztliche Praxis, 1992, Volume: 60, Issue:8

    Topics: Amylases; Child; Child, Preschool; Cholecystokinin; Cystic Fibrosis; Diagnosis, Differential; Exocri

1992
Exocrine pancreatic insufficiency in presumed healthy elderly subjects.
    Age and ageing, 1992, Volume: 21, Issue:4

    Topics: 4-Aminobenzoic Acid; Adolescent; Adult; Aged; Aged, 80 and over; Exocrine Pancreatic Insufficiency;

1992
Fecal immunoreactive lipase: a new tubeless pancreatic function test.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:4

    Topics: Adult; Celiac Disease; Chronic Disease; Clinical Enzyme Tests; Enzyme-Linked Immunosorbent Assay; Ev

1992
Exocrine pancreatic insufficiency-like syndrome in giraffe.
    Journal of wildlife diseases, 1991, Volume: 27, Issue:4

    Topics: Amylases; Animals; Artiodactyla; Diarrhea; Exocrine Pancreatic Insufficiency; Feces; Lipase; Pancrea

1991
Gastric lipase in alcoholic pancreatitis. Comparison of secretive profiles following pentagastrin stimulation in normal adults and patients with pancreatic insufficiency.
    Gastroenterology, 1990, Volume: 99, Issue:1

    Topics: Adult; Alcoholism; Duodenal Ulcer; Exocrine Pancreatic Insufficiency; Gastric Acidity Determination;

1990
Non-invasive assessment of intraluminal lipolysis using a 13CO2 breath test.
    Archives of disease in childhood, 1990, Volume: 65, Issue:6

    Topics: Breath Tests; Caprylates; Carbon Dioxide; Carbon Isotopes; Child; Child, Preschool; Cystic Fibrosis;

1990
Pancreatic insufficiency. Duodenal and jejunal pH, bile acid activity, and micellar lipid solubilization.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1990, Volume: 6, Issue:4

    Topics: Adult; Aged; Bile Acids and Salts; Chronic Disease; Duodenum; Ethanol; Exocrine Pancreatic Insuffici

1990
Isolated lipase and colipase deficiency in two brothers.
    Gut, 1990, Volume: 31, Issue:12

    Topics: Adolescent; Carotenoids; Celiac Disease; Child; Colipases; Exocrine Pancreatic Insufficiency; Humans

1990
Postoperative management of patients with total exocrine pancreatic insufficiency.
    The British journal of surgery, 1990, Volume: 77, Issue:6

    Topics: Adult; Aged; Body Weight; Celiac Disease; Dietary Fats; Duodenum; Exocrine Pancreatic Insufficiency;

1990
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases].
    Schweizerische medizinische Wochenschrift, 1985, Aug-17, Volume: 115, Issue:33

    Topics: Acute Disease; Adult; Aged; Amylases; Chronic Disease; Exocrine Pancreatic Insufficiency; Female; Hu

1985
Total pancreatic insufficiency in pigs: a model to study intestinal enzymes and plasma levels of digestive hormones after pancreatic supplementation by a whole pancreas preparation.
    Pancreas, 1989, Volume: 4, Issue:5

    Topics: Administration, Oral; Amylases; Animals; Cholecystokinin; Chymotrypsin; Disease Models, Animal; Exoc

1989
Pancreatic enzyme supplementation in normal and exocrine pancreatic insufficient pigs.
    Acta veterinaria Scandinavica, 1989, Volume: 30, Issue:4

    Topics: Amylases; Animals; Exocrine Pancreatic Insufficiency; Female; Lipase; Male; Pancreas; Peptide Hydrol

1989
Acid resistant lipase as replacement therapy in chronic pancreatic exocrine insufficiency: a study in dogs.
    Gut, 1989, Volume: 30, Issue:7

    Topics: Animals; Celiac Disease; Chronic Disease; Dogs; Exocrine Pancreatic Insufficiency; Fungal Proteins;

1989
Adsorption of alpha-amylase (EC 3.2.1.1) and lipase (EC 3.1.1.3) before and after substitution therapy in exocrine pancreatic insufficiency.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1988, Volume: 120

    Topics: Adult; alpha-Amylases; Exocrine Pancreatic Insufficiency; Humans; Intestinal Absorption; Lipase; Mal

1988
Use of pancreatic Schilling test to determine efficiency of pancreatic enzyme delivery in pancreatic insufficiency.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:10

    Topics: Adult; Aged; Delayed-Action Preparations; Exocrine Pancreatic Insufficiency; Gastric Juice; Humans;

1988
Duodenal instillation of pancreatin does not abolish steatorrhea in patients with pancreatic insufficiency.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:10

    Topics: Celiac Disease; Dietary Fats; Duodenum; Exocrine Pancreatic Insufficiency; Feces; Humans; Intestinal

1988
[Treatment of exocrine pancreatic insufficiency: where can progress come from?].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:11

    Topics: Animals; Exocrine Pancreatic Insufficiency; Humans; Hydrogen-Ion Concentration; Lipase; Pancreatic E

1988
[The pH dependence of lipase and trypsin activity].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1988, Volume: 48, Issue:3-4

    Topics: Duodenum; Exocrine Pancreatic Insufficiency; Gastric Acidity Determination; Humans; Lipase; Trypsin

1988
Human gastric lipase: variations induced by gastrointestinal hormones and by pathology.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:9

    Topics: Adolescent; Adult; Aged; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Female; Gastric Mucosa;

1988
[Pancreatic enzyme preparations].
    Nederlands tijdschrift voor geneeskunde, 1988, May-28, Volume: 132, Issue:22

    Topics: Dosage Forms; Dose-Response Relationship, Drug; Exocrine Pancreatic Insufficiency; Humans; Lipase

1988
[Exocrine pancreatic insufficiency. Comparison of substitution therapy with a non-acid resistant and an acid resistant enzyme preparation].
    Fortschritte der Medizin, 1986, Sep-04, Volume: 104, Issue:33

    Topics: Adult; Exocrine Pancreatic Insufficiency; Female; Gastric Acidity Determination; Humans; Lipase; Mal

1986
[Pancreatic enzyme preparations].
    Nederlands tijdschrift voor geneeskunde, 1987, Oct-03, Volume: 131, Issue:40

    Topics: Bile Acids and Salts; Drug Combinations; Enzyme Therapy; Exocrine Pancreatic Insufficiency; Humans;

1987
Bile acid secretion in cystic fibrosis: evidence for a defect unrelated to fat malabsorption.
    Gut, 1986, Volume: 27, Issue:9

    Topics: Adolescent; Adult; Bile Acids and Salts; Celiac Disease; Colipases; Cystic Fibrosis; Exocrine Pancre

1986
Role of nonpancreatic lipolytic activity in exocrine pancreatic insufficiency.
    Gastroenterology, 1987, Volume: 92, Issue:1

    Topics: Alcoholism; Dietary Fats; Exocrine Pancreatic Insufficiency; Gastric Juice; Humans; Intestinal Absor

1987
Salivary isoamylase in duodenal aspirates.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:12

    Topics: Adolescent; Adult; Aged; Bicarbonates; Cholecystokinin; Duodenum; Exocrine Pancreatic Insufficiency;

1986
Serum PABA and fluorescein in the course of Bz-Ty-PABA and pancreolauryl test as an index of exocrine pancreatic insufficiency.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:7

    Topics: 4-Aminobenzoic Acid; Adult; Aminobenzoates; Ceruletide; Chymotrypsin; Exocrine Pancreatic Insufficie

1985