1-anilino-8-naphthalenesulfonate has been researched along with Neoplasms in 72 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Excerpt | Relevance | Reference |
---|---|---|
" Peripheral LIF administered to mice caused >50% loss of adipose tissue and >10% reduction in body weight despite only transient hypophagia due to decreasing leptin." | 7.88 | Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. ( Arora, GK; Guo, T; Gupta, A; Infante, RE; Iyengar, P; Narayanan, S, 2018) |
" Peripheral LIF administered to mice caused >50% loss of adipose tissue and >10% reduction in body weight despite only transient hypophagia due to decreasing leptin." | 3.88 | Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. ( Arora, GK; Guo, T; Gupta, A; Infante, RE; Iyengar, P; Narayanan, S, 2018) |
"This review aims to determine the incidence and risk of pancreatic adverse events (AEs) associated with immune checkpoint inhibitors (ICIs) therapy for solid tumors." | 3.01 | Pancreatic adverse events of immune checkpoint inhibitors therapy for solid cancer patients: a systematic review and meta-analysis. ( Liu, J; Liu, S; Pang, L; Zeng, L; Zhang, W; Zhao, Z, 2023) |
"Eligible patients had solid tumors for which treatment with carboplatin/paclitaxel was appropriate." | 2.71 | A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy. ( Arezzo, J; Bartley, P; Chia, M; Daly, M; Davis, ID; Green, M; Harrison, L; Kiers, L; MacGregor, L; Michael, M; Quinn, M; Rosenthal, M, 2005) |
"One hundred seventy-eight patients with cancer were treated with amygdalin (Laetrile) plus a "metabolic therapy" program consisting of diet, enzymes, and vitamins." | 2.65 | A clinical trial of amygdalin (Laetrile) in the treatment of human cancer. ( Currie, VE; Davignon, JP; Fleming, TR; Jones, SE; Koch, R; Kvols, LK; Moertel, CG; Rubin, J; Sarna, G; Young, CW, 1982) |
"However, the roles of ATGL in cancer are still neglected though a putative tumour suppressor function of ATGL has been envisaged, as its expression is frequently reduced in different human cancers (e." | 2.58 | Hints on ATGL implications in cancer: beyond bioenergetic clues. ( Ciccarone, F; Ciriolo, MR; Di Leo, L; Vegliante, R, 2018) |
"One of the major challenges facing cancer therapy today is achieving specificity." | 2.44 | Targeting cancer with bugs and liposomes: ready, aim, fire. ( Cheong, I; Diaz, LA; Huang, X; Thornton, K; Zhou, S, 2007) |
"Bidirectional interactions between cancer cells and their microenvironment govern tumor progression." | 1.91 | Acidosis-induced regulation of adipocyte G0S2 promotes crosstalk between adipocytes and breast cancer cells as well as tumor progression. ( Bindels, L; Brohée, L; Colige, A; Cremer, J; Deroanne, CF; Dupont, L; Lefevre, C; Liu, J; Peiffer, R; Peulen, O; Saarinen, AM, 2023) |
"ATGL expression in these cancer cells is low when compared to MEFs." | 1.56 | Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling. ( Heier, C; Hoefler, G; Kien, B; Schoiswohl, G; Schweiger, M; Sexl, V; Strießnig-Bina, I; Tang, Z; Vesely, PW; Xie, H; Zechner, R, 2020) |
"ICIPI can present as typical acute pancreatitis, with risk of the development of a pseudocyst, diabetes, and chronic pancreatitis." | 1.51 | Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury. ( Abu-Sbeih, H; Altan, M; Coronel, E; Dadu, R; Jazaeri, AA; Lu, Y; Tang, T; Thirumurthi, S; Wang, Y, 2019) |
"Cancer cachexia is a multifactorial metabolic syndrome characterized by marked loss of adipose tissue and skeletal muscle." | 1.46 | Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer. ( Alcântara, PSM; Batista, ML; Lira, FS; Oller do Nascimento, CM; Otoch, JP; Oyama, LM; Seelaender, M; Silvério, R, 2017) |
"Herein, we report that in various cancer cells upon oxygen deprivation, HIF-1 activation down-modulates LD catabolism mediated by adipose triglyceride lipase (ATGL), the key enzyme for intracellular lipolysis." | 1.46 | Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia. ( Hitosugi, T; Ho, TH; Liu, J; Saarinen, AM; Wang, L; Wang, Z; Zhang, X, 2017) |
"Understanding cancer metabolism is instrumental to devise innovative therapeutic approaches." | 1.43 | Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. ( Al-Zoughbi, W; Gorkiewicz, G; Guertl-Lackner, B; Haemmerle, G; Haybaeck, J; Hoefler, G; Jahn, SW; Kindt, AS; Lackner, C; Liegl-Atzwanger, B; Nusshold, E; Pichler, M; Popper, H; Schauer, S; Speicher, MR; Trajanoski, Z; Vesely, PW; Zechner, R; Zimmermann, R, 2016) |
"Differential anticancer drug delivery that selectively releases a drug within a tumor represents an ideal cancer therapy strategy." | 1.39 | Differential anticancer drug delivery with a nanogel sensitive to bacteria-accumulated tumor artificial environment. ( Bao, Y; Du, XJ; Jiang, Q; Tan, ZB; Wang, HX; Wang, J; Xiong, MH; Zhu, YH, 2013) |
"Many anticancer drugs cannot recognize selectively tumor tissues, and cause destruction to normal ones." | 1.38 | Characterization of metalloanticancer capacity of an agglutinin from wheat. ( Bogoeva, VP; Buchvarov, ICh; Ivanov, IB; Kulina, HN; Petrova, LP, 2012) |
"Cachexia is a multifactorial wasting syndrome most common in patients with cancer that is characterized by the uncontrolled loss of adipose and muscle mass." | 1.37 | Adipose triglyceride lipase contributes to cancer-associated cachexia. ( Das, SK; Diwoky, C; Eder, S; Gorkiewicz, G; Guertl, B; Haemmerle, G; Hoefler, G; Kumari, P; Schauer, S; Tamilarasan, KP; Temmel, H; Trauner, M; Vesely, P; Zechner, R; Zimmermann, R, 2011) |
" So far, elevated levels of serum lipase have not been described as a possible side-effect of a liposomal amphotericin B therapy." | 1.31 | Pancreatic toxicity after liposomal amphotericin B. ( Bode, U; Fleischhack, G; Hasan, C; Stuecklin-Utsch, A, 2002) |
"In patients with cancers, PHLA was similar to that of controls, but the HTGL activity was decreased and the LPL activity was increased." | 1.27 | Hepatic triglyceride lipase and lipoprotein lipase activities in post-heparin plasma of patients with various cancers. ( Itoh, Y; Masuno, H; Ohta, Y; Okuda, H; Onji, M; Shiosaka, T, 1985) |
"We have also shown that sera of cancer patients (CPS) possess ethanol-extractable substance(s) which can inhibit the catabolism of cortisol by lymphocytes (CCL)." | 1.27 | Effect of ethanol extract of cancer patients' serum on the vulnerability of lymphocytes to cortisol. ( Bruser, B; Klein, A; Malkin, A, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (40.28) | 18.7374 |
1990's | 5 (6.94) | 18.2507 |
2000's | 5 (6.94) | 29.6817 |
2010's | 24 (33.33) | 24.3611 |
2020's | 9 (12.50) | 2.80 |
Authors | Studies |
---|---|
Xie, Z | 1 |
Hou, S | 1 |
Yang, X | 1 |
Duan, Y | 1 |
Han, J | 1 |
Wang, Q | 1 |
Liao, C | 1 |
Bogoeva, VP | 1 |
Petrova, LP | 1 |
Ivanov, IB | 1 |
Kulina, HN | 1 |
Buchvarov, ICh | 1 |
Sayed Ahmed, A | 1 |
Abreo, M | 1 |
Thomas, A | 1 |
Chari, ST | 1 |
Zhao, Z | 1 |
Zhang, W | 1 |
Pang, L | 1 |
Zeng, L | 1 |
Liu, S | 1 |
Liu, J | 4 |
Cremer, J | 1 |
Brohée, L | 1 |
Dupont, L | 1 |
Lefevre, C | 1 |
Peiffer, R | 1 |
Saarinen, AM | 2 |
Peulen, O | 1 |
Bindels, L | 1 |
Colige, A | 1 |
Deroanne, CF | 1 |
Jovičić, EJ | 1 |
Janež, AP | 1 |
Eichmann, TO | 1 |
Koren, Š | 1 |
Brglez, V | 1 |
Jordan, PM | 1 |
Gerstmeier, J | 1 |
Lainšček, D | 1 |
Golob-Urbanc, A | 1 |
Jerala, R | 1 |
Lambeau, G | 1 |
Werz, O | 1 |
Zimmermann, R | 3 |
Petan, T | 2 |
Xie, H | 1 |
Heier, C | 1 |
Kien, B | 1 |
Vesely, PW | 2 |
Tang, Z | 1 |
Sexl, V | 1 |
Schoiswohl, G | 1 |
Strießnig-Bina, I | 1 |
Hoefler, G | 4 |
Zechner, R | 4 |
Schweiger, M | 1 |
Hong, C | 1 |
Deng, R | 1 |
Wang, P | 1 |
Lu, X | 1 |
Zhao, X | 1 |
Wang, X | 1 |
Cai, R | 1 |
Lin, J | 1 |
Attané, C | 1 |
Muller, C | 1 |
Povero, D | 1 |
Johnson, SM | 1 |
Yu, JE | 1 |
Han, SY | 1 |
Wolfson, B | 1 |
Zhou, Q | 1 |
Kahveci, B | 1 |
Yılmaz, F | 1 |
Menteşe, E | 1 |
Ülker, S | 1 |
Silvério, R | 1 |
Lira, FS | 1 |
Oyama, LM | 1 |
Oller do Nascimento, CM | 1 |
Otoch, JP | 1 |
Alcântara, PSM | 1 |
Batista, ML | 1 |
Seelaender, M | 1 |
Zhang, X | 1 |
Hitosugi, T | 1 |
Wang, Z | 1 |
Wang, L | 1 |
Ho, TH | 1 |
Maan, M | 1 |
Peters, JM | 1 |
Dutta, M | 1 |
Patterson, AD | 1 |
Vegliante, R | 1 |
Di Leo, L | 1 |
Ciccarone, F | 1 |
Ciriolo, MR | 1 |
Wang, C | 1 |
Chen, S | 1 |
Wang, Y | 2 |
Liu, X | 1 |
Hu, F | 1 |
Sun, J | 1 |
Yuan, H | 1 |
Arora, GK | 1 |
Gupta, A | 1 |
Narayanan, S | 1 |
Guo, T | 1 |
Iyengar, P | 1 |
Infante, RE | 1 |
Jarc, E | 1 |
Jusović, M | 1 |
Li, Y | 1 |
Du, L | 1 |
Wu, C | 1 |
Yu, B | 1 |
Zhang, H | 1 |
An, F | 1 |
Abu-Sbeih, H | 1 |
Tang, T | 1 |
Lu, Y | 1 |
Thirumurthi, S | 1 |
Altan, M | 1 |
Jazaeri, AA | 1 |
Dadu, R | 1 |
Coronel, E | 1 |
VandeKopple, MJ | 1 |
Wu, J | 1 |
Auer, EN | 1 |
Giaccia, AJ | 1 |
Denko, NC | 1 |
Papandreou, I | 1 |
Young, SG | 1 |
Das, SK | 2 |
Xiong, MH | 1 |
Bao, Y | 1 |
Du, XJ | 1 |
Tan, ZB | 1 |
Jiang, Q | 1 |
Wang, HX | 1 |
Zhu, YH | 1 |
Wang, J | 1 |
Ramanadham, S | 1 |
Ali, T | 1 |
Ashley, JW | 1 |
Bone, RN | 1 |
Hancock, WD | 1 |
Lei, X | 1 |
Loli, H | 1 |
Narwal, SK | 1 |
Saun, NK | 1 |
Gupta, R | 1 |
Kobayashi, H | 1 |
Nishimura, H | 1 |
Matsumoto, K | 1 |
Yoshida, M | 1 |
Al-Zoughbi, W | 1 |
Pichler, M | 1 |
Gorkiewicz, G | 2 |
Guertl-Lackner, B | 1 |
Haybaeck, J | 1 |
Jahn, SW | 1 |
Lackner, C | 1 |
Liegl-Atzwanger, B | 1 |
Popper, H | 1 |
Schauer, S | 2 |
Nusshold, E | 1 |
Kindt, AS | 1 |
Trajanoski, Z | 1 |
Speicher, MR | 1 |
Haemmerle, G | 2 |
Eder, S | 1 |
Diwoky, C | 1 |
Temmel, H | 1 |
Guertl, B | 1 |
Tamilarasan, KP | 1 |
Kumari, P | 1 |
Trauner, M | 1 |
Vesely, P | 1 |
Arner, P | 1 |
Fearon, KC | 1 |
Kaewpiboon, C | 1 |
Lirdprapamongkol, K | 1 |
Srisomsap, C | 1 |
Winayanuwattikun, P | 1 |
Yongvanich, T | 1 |
Puwaprisirisan, P | 1 |
Svasti, J | 1 |
Assavalapsakul, W | 1 |
Majtán, V | 1 |
Hostacká, A | 1 |
Majtánová, L | 1 |
Trupl, J | 1 |
HINSBERG, K | 1 |
BRUNS, F | 1 |
GEINITZ, W | 1 |
SCHILD, W | 1 |
WUST, H | 1 |
MISCHEL, W | 2 |
CURRI, SB | 1 |
BIRESSI, PC | 1 |
CONCINA, E | 1 |
CORMACK, DH | 2 |
EASTY, GC | 1 |
AMBROSE, EJ | 2 |
GIARETTA, D | 1 |
GAMBILL, EE | 1 |
MASON, HL | 1 |
SHURIN, SP | 1 |
CHASOVSKIKH, GG | 1 |
MIKHAILOVA, LP | 1 |
GRIGOREV, IuA | 1 |
MELESHIN, SV | 1 |
WILCOX, FH | 1 |
WALLACE, R | 1 |
MOYER, AW | 1 |
MISCHEL, A | 1 |
HOARE, R | 1 |
TUBA, J | 2 |
JESKE, I | 1 |
DEL BUONO, G | 1 |
VIOLLIER, G | 1 |
WASER, P | 1 |
Davis, ID | 1 |
Kiers, L | 1 |
MacGregor, L | 1 |
Quinn, M | 1 |
Arezzo, J | 1 |
Green, M | 1 |
Rosenthal, M | 1 |
Chia, M | 1 |
Michael, M | 1 |
Bartley, P | 1 |
Harrison, L | 1 |
Daly, M | 1 |
Juliano, R | 1 |
Cheong, I | 1 |
Huang, X | 1 |
Thornton, K | 1 |
Diaz, LA | 1 |
Zhou, S | 1 |
Moertel, CG | 1 |
Fleming, TR | 1 |
Rubin, J | 1 |
Kvols, LK | 1 |
Sarna, G | 1 |
Koch, R | 1 |
Currie, VE | 1 |
Young, CW | 1 |
Jones, SE | 1 |
Davignon, JP | 1 |
Tomasik, P | 1 |
Ohshio, G | 1 |
Tanaka, T | 1 |
Imamura, T | 1 |
Okada, N | 1 |
Yoshitomi, S | 1 |
Suwa, H | 1 |
Hosotani, R | 1 |
Imamura, M | 1 |
Kwong, LK | 1 |
Ridinger, DN | 1 |
Bandhauer, M | 1 |
Ward, JH | 1 |
Samlowski, WE | 1 |
Iverius, PH | 1 |
Pritchard, H | 1 |
Wilson, DE | 1 |
Diani, G | 1 |
Poma, G | 1 |
Novazzi, F | 1 |
Zanirato, S | 1 |
Porta, C | 1 |
Moroni, M | 1 |
Melzi d'Eril, GV | 1 |
Moratti, R | 1 |
Stuecklin-Utsch, A | 1 |
Hasan, C | 1 |
Bode, U | 1 |
Fleischhack, G | 1 |
Schwartz, MK | 1 |
Spitsyn, IF | 1 |
Kolesnikov, IuN | 1 |
Toskin, KD | 1 |
Schwendner, SW | 1 |
Weichert, JP | 1 |
Longino, MA | 1 |
Gross, MD | 1 |
Counsell, RE | 1 |
Hörl, WH | 1 |
Wanner, C | 1 |
Schollmeyer, P | 1 |
Ogawa, M | 1 |
Richards, BA | 1 |
Masuno, H | 1 |
Shiosaka, T | 1 |
Itoh, Y | 1 |
Onji, M | 1 |
Ohta, Y | 1 |
Okuda, H | 1 |
Klein, A | 1 |
Bruser, B | 1 |
Malkin, A | 1 |
Regelson, W | 1 |
Uhlenbruck, G | 1 |
Pardoe, GI | 1 |
Bird, GW | 1 |
Maunoury, R | 1 |
Febvre, H | 1 |
Burkhardt, G | 1 |
Gabsch, HC | 1 |
Lantsch, H | 1 |
Szreder, W | 1 |
Gross, R | 1 |
Gerhard, W | 1 |
Rassner, G | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Novel Biomarkers of Hypoxia and Metabolism in Clear Cell Renal Cell Carcinoma[NCT05214885] | 300 participants (Anticipated) | Observational | 2022-02-11 | Recruiting | |||
Biochemical and Functional Biomarkers of Cachexia in Cancer Patients[NCT03191955] | 120 participants (Anticipated) | Observational | 2015-11-30 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
19 reviews available for 1-anilino-8-naphthalenesulfonate and Neoplasms
Article | Year |
---|---|
Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts.
Topics: Antineoplastic Agents; Cell Cycle; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Discove | 2022 |
Type 3 autoimmune pancreatitis (immune checkpoint inhibitor-induced pancreatitis).
Topics: Autoimmune Diseases; Autoimmune Pancreatitis; Humans; Immune Checkpoint Inhibitors; Immunotherapy; L | 2022 |
Pancreatic adverse events of immune checkpoint inhibitors therapy for solid cancer patients: a systematic review and meta-analysis.
Topics: Amylases; Humans; Immune Checkpoint Inhibitors; Lipase; Neoplasms; Pancreatitis | 2023 |
LIPG: an inflammation and cancer modulator.
Topics: Humans; Inflammation; Lipase; Neoplasms | 2021 |
Drilling for Oil: Tumor-Surrounding Adipocytes Fueling Cancer.
Topics: Adipocytes; Disease Progression; Energy Metabolism; Extracellular Vesicles; Fatty Acids, Nonesterifi | 2020 |
Hypoxia, hypoxia-inducible gene 2 (HIG2)/HILPDA, and intracellular lipolysis in cancer.
Topics: Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lipase; Lipid Droplets; Lipolysis; | 2020 |
The role of endothelial lipase in lipid metabolism, inflammation, and cancer.
Topics: Animals; Cell Transformation, Neoplastic; Energy Metabolism; Gene Expression Regulation, Enzymologic | 2018 |
Lipid metabolism and lipophagy in cancer.
Topics: Animals; Autophagy; Fatty Acids; Humans; Lipase; Lipid Droplets; Lipid Metabolism; Lipids; Lipolysis | 2018 |
Hints on ATGL implications in cancer: beyond bioenergetic clues.
Topics: Animals; Energy Metabolism; Humans; Lipase; Neoplasms; PPAR alpha; Signal Transduction; Triglyceride | 2018 |
Lipid Droplets in Cancer: Guardians of Fat in a Stressful World.
Topics: Animals; Autophagy; Cell Proliferation; Cell Survival; Fats; Homeostasis; Humans; Lipase; Lipid Drop | 2018 |
Peptide Sequence-Dominated Enzyme-Responsive Nanoplatform for Anticancer Drug Delivery.
Topics: Antineoplastic Agents; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Drug Screening Assa | 2019 |
Biochemistry and pathophysiology of intravascular and intracellular lipolysis.
Topics: Animals; Blood Vessels; Communicable Diseases; Endothelial Cells; Humans; Intracellular Space; Lipas | 2013 |
The role of triglyceride lipases in cancer associated cachexia.
Topics: Animals; Cachexia; Humans; Lipase; Lipid Metabolism; Neoplasms | 2013 |
Calcium-independent phospholipases A2 and their roles in biological processes and diseases.
Topics: Alternative Splicing; Amino Acid Motifs; Calcium; Central Nervous System Diseases; Humans; Inflammat | 2015 |
Lipases in Medicine: An Overview.
Topics: Alzheimer Disease; Animals; Atherosclerosis; Cystic Fibrosis; Humans; Lipase; Medicine; Neoplasms; O | 2015 |
Targeting cancer with bugs and liposomes: ready, aim, fire.
Topics: Animals; Clostridium; Drug Delivery Systems; Humans; Lipase; Liposomes; Models, Molecular; Neoplasms | 2007 |
[The physiological and pathologic role of human gastric lipase].
Topics: Adult; Aging; Child; Cystic Fibrosis; Dietary Fats; Humans; Infant; Lipase; Lipolysis; Neoplasms; Pa | 1995 |
Laboratory aids to diagnosis--enzymes.
Topics: Acid Phosphatase; Alkaline Phosphatase; Amylases; Aryl Hydrocarbon Hydroxylases; Bone Neoplasms; Cli | 1976 |
The growth-regulating activity of polyanions: a theoretical discussion of their place in the intercellular environment and their role in cell physiology.
Topics: Adenosine Triphosphate; Animals; Anticoagulants; Binding Sites; Calcium; Cell Differentiation; Cell | 1968 |
2 trials available for 1-anilino-8-naphthalenesulfonate and Neoplasms
Article | Year |
---|---|
A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytokines; Dose-Response R | 2005 |
A clinical trial of amygdalin (Laetrile) in the treatment of human cancer.
Topics: Adolescent; Adult; Aged; Amygdalin; Clinical Trials as Topic; Cyanides; Female; Humans; Lipase; Male | 1982 |
51 other studies available for 1-anilino-8-naphthalenesulfonate and Neoplasms
Article | Year |
---|---|
Characterization of metalloanticancer capacity of an agglutinin from wheat.
Topics: Anilino Naphthalenesulfonates; Antineoplastic Agents, Phytogenic; Binding Sites; Cisplatin; Drug Car | 2012 |
Acidosis-induced regulation of adipocyte G0S2 promotes crosstalk between adipocytes and breast cancer cells as well as tumor progression.
Topics: Adipocytes; Cell Cycle Proteins; Cell Physiological Phenomena; Lipase; Lipolysis; Neoplasms | 2023 |
Lipid droplets control mitogenic lipid mediator production in human cancer cells.
Topics: Cell Proliferation; Diacylglycerol O-Acyltransferase; Fatty Acids, Unsaturated; Group X Phospholipas | 2023 |
Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
Topics: Adenylate Kinase; Animals; Cell Line; Cell Proliferation; Fibroblasts; Humans; Lipase; Lipolysis; Mi | 2020 |
Design, Synthesis, and Biological Evaluation of Coumarin-Triazole Hybrid Molecules as Potential Antitumor and Pancreatic Lipase Agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Design; Enzyme Inhibitors; Hot Tem | 2017 |
Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer.
Topics: Adipokines; Adipose Tissue, White; Animals; Blotting, Western; Body Weight; Cachexia; Eating; Lipase | 2017 |
Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia.
Topics: Adaptation, Physiological; Fatty Acids; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; | 2017 |
Lipase-Triggered Water-Responsive "Pandora's Box" for Cancer Therapy: Toward Induced Neighboring Effect and Enhanced Drug Penetration.
Topics: Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Drug Liberation; Humans; Lipase; Nanoparticles | 2018 |
Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin.
Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Cachexia; Cell Line; Cytokine Receptor gp130; Cyto | 2018 |
Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury.
Topics: Antineoplastic Agents, Immunological; B7-H1 Antigen; CTLA-4 Antigen; Female; Humans; Lipase; Male; M | 2019 |
HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors.
Topics: Animals; Female; HCT116 Cells; Heterografts; Humans; Lipase; Lipid Droplets; Lipid Metabolism; Mice; | 2019 |
Differential anticancer drug delivery with a nanogel sensitive to bacteria-accumulated tumor artificial environment.
Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; Bacteria; Burkholderia cepacia; Cell Line; Cel | 2013 |
Identification of the determinants of 2-deoxyglucose sensitivity in cancer cells by shRNA library screening.
Topics: Antineoplastic Agents; Biological Transport, Active; Cell Line, Tumor; Coatomer Protein; Deoxyglucos | 2015 |
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; | 2016 |
Adipose triglyceride lipase contributes to cancer-associated cachexia.
Topics: Adipose Tissue, White; Animals; Blood Glucose; Body Mass Index; Body Weight; Cachexia; Cytokines; Fa | 2011 |
Medicine. Lipases in cachexia.
Topics: Adipocytes; Adipose Tissue; Animals; Cachexia; Humans; Lipase; Lipolysis; Lung Neoplasms; Melanoma, | 2011 |
Cancer cachexia and fat-muscle physiology.
Topics: Adipose Tissue; Animals; Cachexia; Disease Models, Animal; Humans; Lipase; Lipolysis; Mice; Muscle, | 2011 |
Studies of the in vitro cytotoxic, antioxidant, lipase inhibitory and antimicrobial activities of selected Thai medicinal plants.
Topics: Allium; Antineoplastic Agents, Phytogenic; Antioxidants; Bacteria; Bauhinia; Cell Line, Tumor; Enzym | 2012 |
Toxinogenicity and markers of pathogenicity of Pseudomonas aeruginosa strains isolated from patients with tumor diseases.
Topics: Alginates; Bacterial Adhesion; Endopeptidases; Glucuronic Acid; Hexuronic Acids; Humans; Lipase; Neo | 2002 |
[Aldolase, dipeptidase, tripeptidase, tributyrinase, phosphatase, amylase, proteins and protein polysaccharides in the blood serum and ascites fluid in the mouse ascites tumor].
Topics: Aminopeptidases; Amylases; Animals; Ascites; Blood; Blood Proteins; Dipeptidases; Fructose-Bisphosph | 1954 |
[Behavior of quinine-fast serum lipase in cancer in women].
Topics: Blood; Fasting; Genitalia; Genitalia, Female; Lipase; Neoplasms; Quinine | 1955 |
[Histochemical findings on pituitary lipase on in cancer patients].
Topics: Humans; Lipase; Neoplasms; Pituitary Diseases; Pituitary Gland | 1955 |
[Histochemical research on acid phosphatases and lipases of bronchi and bronchiopulmonary tumors].
Topics: Acid Phosphatase; Bronchi; Humans; Lipase; Lung Neoplasms; Neoplasms; Phosphoric Monoester Hydrolase | 1957 |
Interaction of enzymes with normal and tumour cells.
Topics: Lipase; Neoplasms; Research Design; Tissue Culture Techniques | 1961 |
[On the lipase actiity and lipid metabolism of the liver in patients with malignant neoplasms].
Topics: Humans; Lipase; Lipid Metabolism; Lipids; Liver; Neoplasms | 1960 |
CYTOLOGICAL STUDIES OF THE ENTRY OF ENZYMES INTO CELLS IN TISSUE CULTURE.
Topics: Animals; Chymotrypsin; Esterases; Lipase; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Res | 1963 |
URINARY AMYLASE VS SERUM AMYLASE IN PATIENTS WITH PANCREATIC CARCINOMA.
Topics: Amylases; Blood Chemical Analysis; Clinical Enzyme Tests; Humans; Lipase; Neoplasms; Pancreatic Neop | 1964 |
[EFFECT OF HEPARIN ON MALIGNANT TUMOR CELLS IN TISSUE CULTURE].
Topics: Acid Phosphatase; Alkaline Phosphatase; Cysteine; Electron Transport Complex II; Electron Transport | 1964 |
SERUM ENZYME LEVELS IN LINES OF CHICKENS DIFFERING IN SUSCEPTIBILITY TO LEUCOSIS.
Topics: Acid Phosphatase; Alkaline Phosphatase; Amylases; Animals; Aspartate Aminotransferases; Cathepsins; | 1964 |
EFFECT OF WHEAT GERM LIPASE ON HUMAN CELLS TRANSFORMED IN VITRO BY SIMIAN VIRUS 40.
Topics: Cytopathogenic Effect, Viral; Humans; In Vitro Techniques; Lipase; Neoplasms; Neoplasms, Experimenta | 1965 |
[Evaluation of atoxylfast lipase determination in blood in cancer diagnosis, with a contribution on atoxylfast blood lipase in gynecological cancer].
Topics: Blood; Female; Genitalia; Genitalia, Female; Gynecology; Humans; Lipase; Neoplasms | 1955 |
Human serum tributyrinase. III. Levels in cancer.
Topics: Hematologic Diseases; Lipase; Lymphatic Diseases; Neoplasms | 1951 |
Serum tributyrinase levels in mice of the C57, C3H, and A strains.
Topics: Animals; Lipase; Lymphatic Diseases; Mice; Mice, Inbred C3H; Neoplasms | 1952 |
[Roentgenotherapy and behavior or tributyrinolytic lipases in the blood in subjects having malignant tumors].
Topics: Hematologic Diseases; Lipase; Lymphatic Diseases; Neoplasms; Radiotherapy; X-Ray Therapy | 1951 |
[Enzymes of benign and malignant tumors of the liver; cholinesterase and tributyrinase].
Topics: Cholinesterases; Enzymes; Humans; Lipase; Liver; Neoplasms | 1950 |
Bugging tumors to put drugs on target.
Topics: Animals; Antineoplastic Agents; Bacterial Proteins; Clostridium; Doxorubicin; Drug Delivery Systems; | 2007 |
Exocrine pancreatic function in the early period after pancreatoduodenectomy and effects of preoperative pancreatic duct obstruction.
Topics: 4-Aminobenzoic Acid; Amylases; Constriction, Pathologic; Female; Humans; Lipase; Male; Middle Aged; | 1996 |
Acute dyslipoproteinemia induced by interleukin-2: lecithin:cholesteryl acyltransferase, lipoprotein lipase, and hepatic lipase deficiencies.
Topics: Apolipoprotein A-I; Apolipoproteins B; Apolipoproteins E; Chemical and Drug Induced Liver Injury; Ch | 1997 |
Increased serum lipase with associated normoamylasemia in cancer patients.
Topics: Adenocarcinoma; alpha-Amylases; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Colorectal Neoplas | 1998 |
Pancreatic toxicity after liposomal amphotericin B.
Topics: Adolescent; Amphotericin B; Child; Child, Preschool; Female; Humans; Infant; Lipase; Liposomes; Male | 2002 |
[Pancreatic enzymatic activity in the blood and urine in tumors of varying localization].
Topics: Amylases; Enzyme Activation; Female; Humans; Lipase; Neoplasms; Pancreas; Pancreatic Diseases; Pepti | 1978 |
Potential organ or tumor imaging agents. 32. A triglyceride ester of p-iodophenyl pentadecanoic acid as a potential hepatic imaging agent.
Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Evaluation Studies as Topic; Female; Gamma Cameras; | 1992 |
Plasma levels of pancreatic secretory trypsin inhibitor in relation to amylase and lipase in patients with acute and chronic renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Amylases; Humans; Kidney Failure, Chronic; Kidney Transplantation; | 1988 |
The enzyme knife--a renewed direction for cancer therapy? Discussion paper.
Topics: Amylases; Enzyme Therapy; Humans; Lipase; Neoplasms; Pancreatin; Trophoblasts | 1988 |
Hepatic triglyceride lipase and lipoprotein lipase activities in post-heparin plasma of patients with various cancers.
Topics: Aged; Carcinoma, Hepatocellular; Cholesterol; Female; Humans; Lipase; Lipoprotein Lipase; Lipoprotei | 1985 |
Effect of ethanol extract of cancer patients' serum on the vulnerability of lymphocytes to cortisol.
Topics: Deoxyribonucleases; Ethanol; Humans; Hydrocortisone; Lipase; Lymphocytes; Neoplasms; Pronase; Ribonu | 1988 |
[On the specificity of the tumor cell-characteristic agglutinins of "wheat germ lipase"].
Topics: ABO Blood-Group System; Antibodies; Chitin; Hemagglutination Inhibition Tests; Lipase; Neoplasms; Ol | 1968 |
[Demonstration of lectin receptor sites on the membrane of human tumoral cells].
Topics: Agglutination Tests; Astrocytoma; Avian Sarcoma Viruses; Binding Sites; Carcinoma; Cell Line; Cell M | 1971 |
[Serum lipase determination within the scope of pancreas diagnosis].
Topics: Amylases; Biliary Tract Diseases; Clinical Enzyme Tests; Colorimetry; Fractures, Bone; Humans; Lipas | 1967 |
Effect of artificially induced abacterial erysipelas and of chronic aseptic abscess on human and experimental neoplasms.
Topics: Abscess; Adult; Aged; Amylases; Anemia; Animals; Breast Neoplasms; Child; Erysipelas; Eye Neoplasms; | 1968 |
[A simple method for separation of accelerated sedimentation caused by tumor and inflammation].
Topics: Blood Proteins; Blood Sedimentation; Diagnosis, Differential; Humans; Inflammation; Lipase; Neoplasm | 1966 |