Page last updated: 2024-10-21

1-anilino-8-naphthalenesulfonate and Neoplasms

1-anilino-8-naphthalenesulfonate has been researched along with Neoplasms in 72 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" Peripheral LIF administered to mice caused >50% loss of adipose tissue and >10% reduction in body weight despite only transient hypophagia due to decreasing leptin."7.88Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. ( Arora, GK; Guo, T; Gupta, A; Infante, RE; Iyengar, P; Narayanan, S, 2018)
" Peripheral LIF administered to mice caused >50% loss of adipose tissue and >10% reduction in body weight despite only transient hypophagia due to decreasing leptin."3.88Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. ( Arora, GK; Guo, T; Gupta, A; Infante, RE; Iyengar, P; Narayanan, S, 2018)
"This review aims to determine the incidence and risk of pancreatic adverse events (AEs) associated with immune checkpoint inhibitors (ICIs) therapy for solid tumors."3.01Pancreatic adverse events of immune checkpoint inhibitors therapy for solid cancer patients: a systematic review and meta-analysis. ( Liu, J; Liu, S; Pang, L; Zeng, L; Zhang, W; Zhao, Z, 2023)
"Eligible patients had solid tumors for which treatment with carboplatin/paclitaxel was appropriate."2.71A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy. ( Arezzo, J; Bartley, P; Chia, M; Daly, M; Davis, ID; Green, M; Harrison, L; Kiers, L; MacGregor, L; Michael, M; Quinn, M; Rosenthal, M, 2005)
"One hundred seventy-eight patients with cancer were treated with amygdalin (Laetrile) plus a "metabolic therapy" program consisting of diet, enzymes, and vitamins."2.65A clinical trial of amygdalin (Laetrile) in the treatment of human cancer. ( Currie, VE; Davignon, JP; Fleming, TR; Jones, SE; Koch, R; Kvols, LK; Moertel, CG; Rubin, J; Sarna, G; Young, CW, 1982)
"However, the roles of ATGL in cancer are still neglected though a putative tumour suppressor function of ATGL has been envisaged, as its expression is frequently reduced in different human cancers (e."2.58Hints on ATGL implications in cancer: beyond bioenergetic clues. ( Ciccarone, F; Ciriolo, MR; Di Leo, L; Vegliante, R, 2018)
"One of the major challenges facing cancer therapy today is achieving specificity."2.44Targeting cancer with bugs and liposomes: ready, aim, fire. ( Cheong, I; Diaz, LA; Huang, X; Thornton, K; Zhou, S, 2007)
"Bidirectional interactions between cancer cells and their microenvironment govern tumor progression."1.91Acidosis-induced regulation of adipocyte G0S2 promotes crosstalk between adipocytes and breast cancer cells as well as tumor progression. ( Bindels, L; Brohée, L; Colige, A; Cremer, J; Deroanne, CF; Dupont, L; Lefevre, C; Liu, J; Peiffer, R; Peulen, O; Saarinen, AM, 2023)
"ATGL expression in these cancer cells is low when compared to MEFs."1.56Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling. ( Heier, C; Hoefler, G; Kien, B; Schoiswohl, G; Schweiger, M; Sexl, V; Strießnig-Bina, I; Tang, Z; Vesely, PW; Xie, H; Zechner, R, 2020)
"ICIPI can present as typical acute pancreatitis, with risk of the development of a pseudocyst, diabetes, and chronic pancreatitis."1.51Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury. ( Abu-Sbeih, H; Altan, M; Coronel, E; Dadu, R; Jazaeri, AA; Lu, Y; Tang, T; Thirumurthi, S; Wang, Y, 2019)
"Cancer cachexia is a multifactorial metabolic syndrome characterized by marked loss of adipose tissue and skeletal muscle."1.46Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer. ( Alcântara, PSM; Batista, ML; Lira, FS; Oller do Nascimento, CM; Otoch, JP; Oyama, LM; Seelaender, M; Silvério, R, 2017)
"Herein, we report that in various cancer cells upon oxygen deprivation, HIF-1 activation down-modulates LD catabolism mediated by adipose triglyceride lipase (ATGL), the key enzyme for intracellular lipolysis."1.46Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia. ( Hitosugi, T; Ho, TH; Liu, J; Saarinen, AM; Wang, L; Wang, Z; Zhang, X, 2017)
"Understanding cancer metabolism is instrumental to devise innovative therapeutic approaches."1.43Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. ( Al-Zoughbi, W; Gorkiewicz, G; Guertl-Lackner, B; Haemmerle, G; Haybaeck, J; Hoefler, G; Jahn, SW; Kindt, AS; Lackner, C; Liegl-Atzwanger, B; Nusshold, E; Pichler, M; Popper, H; Schauer, S; Speicher, MR; Trajanoski, Z; Vesely, PW; Zechner, R; Zimmermann, R, 2016)
"Differential anticancer drug delivery that selectively releases a drug within a tumor represents an ideal cancer therapy strategy."1.39Differential anticancer drug delivery with a nanogel sensitive to bacteria-accumulated tumor artificial environment. ( Bao, Y; Du, XJ; Jiang, Q; Tan, ZB; Wang, HX; Wang, J; Xiong, MH; Zhu, YH, 2013)
"Many anticancer drugs cannot recognize selectively tumor tissues, and cause destruction to normal ones."1.38Characterization of metalloanticancer capacity of an agglutinin from wheat. ( Bogoeva, VP; Buchvarov, ICh; Ivanov, IB; Kulina, HN; Petrova, LP, 2012)
"Cachexia is a multifactorial wasting syndrome most common in patients with cancer that is characterized by the uncontrolled loss of adipose and muscle mass."1.37Adipose triglyceride lipase contributes to cancer-associated cachexia. ( Das, SK; Diwoky, C; Eder, S; Gorkiewicz, G; Guertl, B; Haemmerle, G; Hoefler, G; Kumari, P; Schauer, S; Tamilarasan, KP; Temmel, H; Trauner, M; Vesely, P; Zechner, R; Zimmermann, R, 2011)
" So far, elevated levels of serum lipase have not been described as a possible side-effect of a liposomal amphotericin B therapy."1.31Pancreatic toxicity after liposomal amphotericin B. ( Bode, U; Fleischhack, G; Hasan, C; Stuecklin-Utsch, A, 2002)
"In patients with cancers, PHLA was similar to that of controls, but the HTGL activity was decreased and the LPL activity was increased."1.27Hepatic triglyceride lipase and lipoprotein lipase activities in post-heparin plasma of patients with various cancers. ( Itoh, Y; Masuno, H; Ohta, Y; Okuda, H; Onji, M; Shiosaka, T, 1985)
"We have also shown that sera of cancer patients (CPS) possess ethanol-extractable substance(s) which can inhibit the catabolism of cortisol by lymphocytes (CCL)."1.27Effect of ethanol extract of cancer patients' serum on the vulnerability of lymphocytes to cortisol. ( Bruser, B; Klein, A; Malkin, A, 1988)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199029 (40.28)18.7374
1990's5 (6.94)18.2507
2000's5 (6.94)29.6817
2010's24 (33.33)24.3611
2020's9 (12.50)2.80

Authors

AuthorsStudies
Xie, Z1
Hou, S1
Yang, X1
Duan, Y1
Han, J1
Wang, Q1
Liao, C1
Bogoeva, VP1
Petrova, LP1
Ivanov, IB1
Kulina, HN1
Buchvarov, ICh1
Sayed Ahmed, A1
Abreo, M1
Thomas, A1
Chari, ST1
Zhao, Z1
Zhang, W1
Pang, L1
Zeng, L1
Liu, S1
Liu, J4
Cremer, J1
Brohée, L1
Dupont, L1
Lefevre, C1
Peiffer, R1
Saarinen, AM2
Peulen, O1
Bindels, L1
Colige, A1
Deroanne, CF1
Jovičić, EJ1
Janež, AP1
Eichmann, TO1
Koren, Š1
Brglez, V1
Jordan, PM1
Gerstmeier, J1
Lainšček, D1
Golob-Urbanc, A1
Jerala, R1
Lambeau, G1
Werz, O1
Zimmermann, R3
Petan, T2
Xie, H1
Heier, C1
Kien, B1
Vesely, PW2
Tang, Z1
Sexl, V1
Schoiswohl, G1
Strießnig-Bina, I1
Hoefler, G4
Zechner, R4
Schweiger, M1
Hong, C1
Deng, R1
Wang, P1
Lu, X1
Zhao, X1
Wang, X1
Cai, R1
Lin, J1
Attané, C1
Muller, C1
Povero, D1
Johnson, SM1
Yu, JE1
Han, SY1
Wolfson, B1
Zhou, Q1
Kahveci, B1
Yılmaz, F1
Menteşe, E1
Ülker, S1
Silvério, R1
Lira, FS1
Oyama, LM1
Oller do Nascimento, CM1
Otoch, JP1
Alcântara, PSM1
Batista, ML1
Seelaender, M1
Zhang, X1
Hitosugi, T1
Wang, Z1
Wang, L1
Ho, TH1
Maan, M1
Peters, JM1
Dutta, M1
Patterson, AD1
Vegliante, R1
Di Leo, L1
Ciccarone, F1
Ciriolo, MR1
Wang, C1
Chen, S1
Wang, Y2
Liu, X1
Hu, F1
Sun, J1
Yuan, H1
Arora, GK1
Gupta, A1
Narayanan, S1
Guo, T1
Iyengar, P1
Infante, RE1
Jarc, E1
Jusović, M1
Li, Y1
Du, L1
Wu, C1
Yu, B1
Zhang, H1
An, F1
Abu-Sbeih, H1
Tang, T1
Lu, Y1
Thirumurthi, S1
Altan, M1
Jazaeri, AA1
Dadu, R1
Coronel, E1
VandeKopple, MJ1
Wu, J1
Auer, EN1
Giaccia, AJ1
Denko, NC1
Papandreou, I1
Young, SG1
Das, SK2
Xiong, MH1
Bao, Y1
Du, XJ1
Tan, ZB1
Jiang, Q1
Wang, HX1
Zhu, YH1
Wang, J1
Ramanadham, S1
Ali, T1
Ashley, JW1
Bone, RN1
Hancock, WD1
Lei, X1
Loli, H1
Narwal, SK1
Saun, NK1
Gupta, R1
Kobayashi, H1
Nishimura, H1
Matsumoto, K1
Yoshida, M1
Al-Zoughbi, W1
Pichler, M1
Gorkiewicz, G2
Guertl-Lackner, B1
Haybaeck, J1
Jahn, SW1
Lackner, C1
Liegl-Atzwanger, B1
Popper, H1
Schauer, S2
Nusshold, E1
Kindt, AS1
Trajanoski, Z1
Speicher, MR1
Haemmerle, G2
Eder, S1
Diwoky, C1
Temmel, H1
Guertl, B1
Tamilarasan, KP1
Kumari, P1
Trauner, M1
Vesely, P1
Arner, P1
Fearon, KC1
Kaewpiboon, C1
Lirdprapamongkol, K1
Srisomsap, C1
Winayanuwattikun, P1
Yongvanich, T1
Puwaprisirisan, P1
Svasti, J1
Assavalapsakul, W1
Majtán, V1
Hostacká, A1
Majtánová, L1
Trupl, J1
HINSBERG, K1
BRUNS, F1
GEINITZ, W1
SCHILD, W1
WUST, H1
MISCHEL, W2
CURRI, SB1
BIRESSI, PC1
CONCINA, E1
CORMACK, DH2
EASTY, GC1
AMBROSE, EJ2
GIARETTA, D1
GAMBILL, EE1
MASON, HL1
SHURIN, SP1
CHASOVSKIKH, GG1
MIKHAILOVA, LP1
GRIGOREV, IuA1
MELESHIN, SV1
WILCOX, FH1
WALLACE, R1
MOYER, AW1
MISCHEL, A1
HOARE, R1
TUBA, J2
JESKE, I1
DEL BUONO, G1
VIOLLIER, G1
WASER, P1
Davis, ID1
Kiers, L1
MacGregor, L1
Quinn, M1
Arezzo, J1
Green, M1
Rosenthal, M1
Chia, M1
Michael, M1
Bartley, P1
Harrison, L1
Daly, M1
Juliano, R1
Cheong, I1
Huang, X1
Thornton, K1
Diaz, LA1
Zhou, S1
Moertel, CG1
Fleming, TR1
Rubin, J1
Kvols, LK1
Sarna, G1
Koch, R1
Currie, VE1
Young, CW1
Jones, SE1
Davignon, JP1
Tomasik, P1
Ohshio, G1
Tanaka, T1
Imamura, T1
Okada, N1
Yoshitomi, S1
Suwa, H1
Hosotani, R1
Imamura, M1
Kwong, LK1
Ridinger, DN1
Bandhauer, M1
Ward, JH1
Samlowski, WE1
Iverius, PH1
Pritchard, H1
Wilson, DE1
Diani, G1
Poma, G1
Novazzi, F1
Zanirato, S1
Porta, C1
Moroni, M1
Melzi d'Eril, GV1
Moratti, R1
Stuecklin-Utsch, A1
Hasan, C1
Bode, U1
Fleischhack, G1
Schwartz, MK1
Spitsyn, IF1
Kolesnikov, IuN1
Toskin, KD1
Schwendner, SW1
Weichert, JP1
Longino, MA1
Gross, MD1
Counsell, RE1
Hörl, WH1
Wanner, C1
Schollmeyer, P1
Ogawa, M1
Richards, BA1
Masuno, H1
Shiosaka, T1
Itoh, Y1
Onji, M1
Ohta, Y1
Okuda, H1
Klein, A1
Bruser, B1
Malkin, A1
Regelson, W1
Uhlenbruck, G1
Pardoe, GI1
Bird, GW1
Maunoury, R1
Febvre, H1
Burkhardt, G1
Gabsch, HC1
Lantsch, H1
Szreder, W1
Gross, R1
Gerhard, W1
Rassner, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Novel Biomarkers of Hypoxia and Metabolism in Clear Cell Renal Cell Carcinoma[NCT05214885]300 participants (Anticipated)Observational2022-02-11Recruiting
Biochemical and Functional Biomarkers of Cachexia in Cancer Patients[NCT03191955]120 participants (Anticipated)Observational2015-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for 1-anilino-8-naphthalenesulfonate and Neoplasms

ArticleYear
Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts.
    Journal of medicinal chemistry, 2022, 05-12, Volume: 65, Issue:9

    Topics: Antineoplastic Agents; Cell Cycle; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Discove

2022
Type 3 autoimmune pancreatitis (immune checkpoint inhibitor-induced pancreatitis).
    Current opinion in gastroenterology, 2022, 09-01, Volume: 38, Issue:5

    Topics: Autoimmune Diseases; Autoimmune Pancreatitis; Humans; Immune Checkpoint Inhibitors; Immunotherapy; L

2022
Pancreatic adverse events of immune checkpoint inhibitors therapy for solid cancer patients: a systematic review and meta-analysis.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Amylases; Humans; Immune Checkpoint Inhibitors; Lipase; Neoplasms; Pancreatitis

2023
LIPG: an inflammation and cancer modulator.
    Cancer gene therapy, 2021, Volume: 28, Issue:1-2

    Topics: Humans; Inflammation; Lipase; Neoplasms

2021
Drilling for Oil: Tumor-Surrounding Adipocytes Fueling Cancer.
    Trends in cancer, 2020, Volume: 6, Issue:7

    Topics: Adipocytes; Disease Progression; Energy Metabolism; Extracellular Vesicles; Fatty Acids, Nonesterifi

2020
Hypoxia, hypoxia-inducible gene 2 (HIG2)/HILPDA, and intracellular lipolysis in cancer.
    Cancer letters, 2020, 11-28, Volume: 493

    Topics: Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lipase; Lipid Droplets; Lipolysis;

2020
The role of endothelial lipase in lipid metabolism, inflammation, and cancer.
    Histology and histopathology, 2018, Volume: 33, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Energy Metabolism; Gene Expression Regulation, Enzymologic

2018
Lipid metabolism and lipophagy in cancer.
    Biochemical and biophysical research communications, 2018, 10-07, Volume: 504, Issue:3

    Topics: Animals; Autophagy; Fatty Acids; Humans; Lipase; Lipid Droplets; Lipid Metabolism; Lipids; Lipolysis

2018
Hints on ATGL implications in cancer: beyond bioenergetic clues.
    Cell death & disease, 2018, 02-22, Volume: 9, Issue:3

    Topics: Animals; Energy Metabolism; Humans; Lipase; Neoplasms; PPAR alpha; Signal Transduction; Triglyceride

2018
Lipid Droplets in Cancer: Guardians of Fat in a Stressful World.
    Molecules (Basel, Switzerland), 2018, Aug-03, Volume: 23, Issue:8

    Topics: Animals; Autophagy; Cell Proliferation; Cell Survival; Fats; Homeostasis; Humans; Lipase; Lipid Drop

2018
Peptide Sequence-Dominated Enzyme-Responsive Nanoplatform for Anticancer Drug Delivery.
    Current topics in medicinal chemistry, 2019, Volume: 19, Issue:1

    Topics: Antineoplastic Agents; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Drug Screening Assa

2019
Biochemistry and pathophysiology of intravascular and intracellular lipolysis.
    Genes & development, 2013, Mar-01, Volume: 27, Issue:5

    Topics: Animals; Blood Vessels; Communicable Diseases; Endothelial Cells; Humans; Intracellular Space; Lipas

2013
The role of triglyceride lipases in cancer associated cachexia.
    Trends in molecular medicine, 2013, Volume: 19, Issue:5

    Topics: Animals; Cachexia; Humans; Lipase; Lipid Metabolism; Neoplasms

2013
Calcium-independent phospholipases A2 and their roles in biological processes and diseases.
    Journal of lipid research, 2015, Volume: 56, Issue:9

    Topics: Alternative Splicing; Amino Acid Motifs; Calcium; Central Nervous System Diseases; Humans; Inflammat

2015
Lipases in Medicine: An Overview.
    Mini reviews in medicinal chemistry, 2015, Volume: 15, Issue:14

    Topics: Alzheimer Disease; Animals; Atherosclerosis; Cystic Fibrosis; Humans; Lipase; Medicine; Neoplasms; O

2015
Targeting cancer with bugs and liposomes: ready, aim, fire.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Animals; Clostridium; Drug Delivery Systems; Humans; Lipase; Liposomes; Models, Molecular; Neoplasms

2007
[The physiological and pathologic role of human gastric lipase].
    Przeglad lekarski, 1995, Volume: 52, Issue:6

    Topics: Adult; Aging; Child; Cystic Fibrosis; Dietary Fats; Humans; Infant; Lipase; Lipolysis; Neoplasms; Pa

1995
Laboratory aids to diagnosis--enzymes.
    Cancer, 1976, Volume: 37, Issue:1 suppl

    Topics: Acid Phosphatase; Alkaline Phosphatase; Amylases; Aryl Hydrocarbon Hydroxylases; Bone Neoplasms; Cli

1976
The growth-regulating activity of polyanions: a theoretical discussion of their place in the intercellular environment and their role in cell physiology.
    Advances in cancer research, 1968, Volume: 11

    Topics: Adenosine Triphosphate; Animals; Anticoagulants; Binding Sites; Calcium; Cell Differentiation; Cell

1968

Trials

2 trials available for 1-anilino-8-naphthalenesulfonate and Neoplasms

ArticleYear
A randomized, double-blinded, placebo-controlled phase II trial of recombinant human leukemia inhibitory factor (rhuLIF, emfilermin, AM424) to prevent chemotherapy-induced peripheral neuropathy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Mar-01, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytokines; Dose-Response R

2005
A clinical trial of amygdalin (Laetrile) in the treatment of human cancer.
    The New England journal of medicine, 1982, Jan-28, Volume: 306, Issue:4

    Topics: Adolescent; Adult; Aged; Amygdalin; Clinical Trials as Topic; Cyanides; Female; Humans; Lipase; Male

1982

Other Studies

51 other studies available for 1-anilino-8-naphthalenesulfonate and Neoplasms

ArticleYear
Characterization of metalloanticancer capacity of an agglutinin from wheat.
    Molecular bioSystems, 2012, Volume: 8, Issue:10

    Topics: Anilino Naphthalenesulfonates; Antineoplastic Agents, Phytogenic; Binding Sites; Cisplatin; Drug Car

2012
Acidosis-induced regulation of adipocyte G0S2 promotes crosstalk between adipocytes and breast cancer cells as well as tumor progression.
    Cancer letters, 2023, 08-10, Volume: 569

    Topics: Adipocytes; Cell Cycle Proteins; Cell Physiological Phenomena; Lipase; Lipolysis; Neoplasms

2023
Lipid droplets control mitogenic lipid mediator production in human cancer cells.
    Molecular metabolism, 2023, Volume: 76

    Topics: Cell Proliferation; Diacylglycerol O-Acyltransferase; Fatty Acids, Unsaturated; Group X Phospholipas

2023
Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020, Volume: 1865, Issue:9

    Topics: Adenylate Kinase; Animals; Cell Line; Cell Proliferation; Fibroblasts; Humans; Lipase; Lipolysis; Mi

2020
Design, Synthesis, and Biological Evaluation of Coumarin-Triazole Hybrid Molecules as Potential Antitumor and Pancreatic Lipase Agents.
    Archiv der Pharmazie, 2017, Volume: 350, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Design; Enzyme Inhibitors; Hot Tem

2017
Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer.
    Lipids in health and disease, 2017, Aug-22, Volume: 16, Issue:1

    Topics: Adipokines; Adipose Tissue, White; Animals; Blotting, Western; Body Weight; Cachexia; Eating; Lipase

2017
Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia.
    eLife, 2017, 12-19, Volume: 6

    Topics: Adaptation, Physiological; Fatty Acids; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit;

2017
Lipase-Triggered Water-Responsive "Pandora's Box" for Cancer Therapy: Toward Induced Neighboring Effect and Enhanced Drug Penetration.
    Advanced materials (Deerfield Beach, Fla.), 2018, Volume: 30, Issue:14

    Topics: Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Drug Liberation; Humans; Lipase; Nanoparticles

2018
Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin.
    JCI insight, 2018, 07-26, Volume: 3, Issue:14

    Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Cachexia; Cell Line; Cytokine Receptor gp130; Cyto

2018
Clinical characteristics and outcomes of immune checkpoint inhibitor-induced pancreatic injury.
    Journal for immunotherapy of cancer, 2019, 02-06, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Immunological; B7-H1 Antigen; CTLA-4 Antigen; Female; Humans; Lipase; Male; M

2019
HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors.
    Molecular cancer research : MCR, 2019, Volume: 17, Issue:10

    Topics: Animals; Female; HCT116 Cells; Heterografts; Humans; Lipase; Lipid Droplets; Lipid Metabolism; Mice;

2019
Differential anticancer drug delivery with a nanogel sensitive to bacteria-accumulated tumor artificial environment.
    ACS nano, 2013, Dec-23, Volume: 7, Issue:12

    Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; Bacteria; Burkholderia cepacia; Cell Line; Cel

2013
Identification of the determinants of 2-deoxyglucose sensitivity in cancer cells by shRNA library screening.
    Biochemical and biophysical research communications, 2015, Nov-06, Volume: 467, Issue:1

    Topics: Antineoplastic Agents; Biological Transport, Active; Cell Line, Tumor; Coatomer Protein; Deoxyglucos

2015
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic;

2016
Adipose triglyceride lipase contributes to cancer-associated cachexia.
    Science (New York, N.Y.), 2011, Jul-08, Volume: 333, Issue:6039

    Topics: Adipose Tissue, White; Animals; Blood Glucose; Body Mass Index; Body Weight; Cachexia; Cytokines; Fa

2011
Medicine. Lipases in cachexia.
    Science (New York, N.Y.), 2011, Jul-08, Volume: 333, Issue:6039

    Topics: Adipocytes; Adipose Tissue; Animals; Cachexia; Humans; Lipase; Lipolysis; Lung Neoplasms; Melanoma,

2011
Cancer cachexia and fat-muscle physiology.
    The New England journal of medicine, 2011, Aug-11, Volume: 365, Issue:6

    Topics: Adipose Tissue; Animals; Cachexia; Disease Models, Animal; Humans; Lipase; Lipolysis; Mice; Muscle,

2011
Studies of the in vitro cytotoxic, antioxidant, lipase inhibitory and antimicrobial activities of selected Thai medicinal plants.
    BMC complementary and alternative medicine, 2012, Nov-13, Volume: 12

    Topics: Allium; Antineoplastic Agents, Phytogenic; Antioxidants; Bacteria; Bauhinia; Cell Line, Tumor; Enzym

2012
Toxinogenicity and markers of pathogenicity of Pseudomonas aeruginosa strains isolated from patients with tumor diseases.
    Folia microbiologica, 2002, Volume: 47, Issue:4

    Topics: Alginates; Bacterial Adhesion; Endopeptidases; Glucuronic Acid; Hexuronic Acids; Humans; Lipase; Neo

2002
[Aldolase, dipeptidase, tripeptidase, tributyrinase, phosphatase, amylase, proteins and protein polysaccharides in the blood serum and ascites fluid in the mouse ascites tumor].
    Zeitschrift fur Krebsforschung, 1954, Volume: 60, Issue:1

    Topics: Aminopeptidases; Amylases; Animals; Ascites; Blood; Blood Proteins; Dipeptidases; Fructose-Bisphosph

1954
[Behavior of quinine-fast serum lipase in cancer in women].
    Archiv fur Geschwulstforschung, 1955, Volume: 8, Issue:2

    Topics: Blood; Fasting; Genitalia; Genitalia, Female; Lipase; Neoplasms; Quinine

1955
[Histochemical findings on pituitary lipase on in cancer patients].
    Rivista di anatomia patologica e di oncologia, 1955, Volume: 9, Issue:5

    Topics: Humans; Lipase; Neoplasms; Pituitary Diseases; Pituitary Gland

1955
[Histochemical research on acid phosphatases and lipases of bronchi and bronchiopulmonary tumors].
    Minerva medica, 1957, May-02, Volume: 48, Issue:35

    Topics: Acid Phosphatase; Bronchi; Humans; Lipase; Lung Neoplasms; Neoplasms; Phosphoric Monoester Hydrolase

1957
Interaction of enzymes with normal and tumour cells.
    Nature, 1961, Jun-24, Volume: 190

    Topics: Lipase; Neoplasms; Research Design; Tissue Culture Techniques

1961
[On the lipase actiity and lipid metabolism of the liver in patients with malignant neoplasms].
    Minerva chirurgica, 1960, Dec-15, Volume: 15

    Topics: Humans; Lipase; Lipid Metabolism; Lipids; Liver; Neoplasms

1960
CYTOLOGICAL STUDIES OF THE ENTRY OF ENZYMES INTO CELLS IN TISSUE CULTURE.
    Experimental cell research, 1963, Volume: 31

    Topics: Animals; Chymotrypsin; Esterases; Lipase; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Res

1963
URINARY AMYLASE VS SERUM AMYLASE IN PATIENTS WITH PANCREATIC CARCINOMA.
    JAMA, 1964, Jun-01, Volume: 188

    Topics: Amylases; Blood Chemical Analysis; Clinical Enzyme Tests; Humans; Lipase; Neoplasms; Pancreatic Neop

1964
[EFFECT OF HEPARIN ON MALIGNANT TUMOR CELLS IN TISSUE CULTURE].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Acid Phosphatase; Alkaline Phosphatase; Cysteine; Electron Transport Complex II; Electron Transport

1964
SERUM ENZYME LEVELS IN LINES OF CHICKENS DIFFERING IN SUSCEPTIBILITY TO LEUCOSIS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Acid Phosphatase; Alkaline Phosphatase; Amylases; Animals; Aspartate Aminotransferases; Cathepsins;

1964
EFFECT OF WHEAT GERM LIPASE ON HUMAN CELLS TRANSFORMED IN VITRO BY SIMIAN VIRUS 40.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: Cytopathogenic Effect, Viral; Humans; In Vitro Techniques; Lipase; Neoplasms; Neoplasms, Experimenta

1965
[Evaluation of atoxylfast lipase determination in blood in cancer diagnosis, with a contribution on atoxylfast blood lipase in gynecological cancer].
    Zentralblatt fur Gynakologie, 1955, Volume: 77, Issue:2

    Topics: Blood; Female; Genitalia; Genitalia, Female; Gynecology; Humans; Lipase; Neoplasms

1955
Human serum tributyrinase. III. Levels in cancer.
    The Journal of laboratory and clinical medicine, 1951, Volume: 38, Issue:4

    Topics: Hematologic Diseases; Lipase; Lymphatic Diseases; Neoplasms

1951
Serum tributyrinase levels in mice of the C57, C3H, and A strains.
    Cancer research, 1952, Volume: 12, Issue:2

    Topics: Animals; Lipase; Lymphatic Diseases; Mice; Mice, Inbred C3H; Neoplasms

1952
[Roentgenotherapy and behavior or tributyrinolytic lipases in the blood in subjects having malignant tumors].
    Radioterapia, radiobiologia e fisica medica, 1951, Volume: 4, Issue:1

    Topics: Hematologic Diseases; Lipase; Lymphatic Diseases; Neoplasms; Radiotherapy; X-Ray Therapy

1951
[Enzymes of benign and malignant tumors of the liver; cholinesterase and tributyrinase].
    Helvetica physiologica et pharmacologica acta, 1950, Volume: 8, Issue:2

    Topics: Cholinesterases; Enzymes; Humans; Lipase; Liver; Neoplasms

1950
Bugging tumors to put drugs on target.
    The New England journal of medicine, 2007, Mar-01, Volume: 356, Issue:9

    Topics: Animals; Antineoplastic Agents; Bacterial Proteins; Clostridium; Doxorubicin; Drug Delivery Systems;

2007
Exocrine pancreatic function in the early period after pancreatoduodenectomy and effects of preoperative pancreatic duct obstruction.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:10

    Topics: 4-Aminobenzoic Acid; Amylases; Constriction, Pathologic; Female; Humans; Lipase; Male; Middle Aged;

1996
Acute dyslipoproteinemia induced by interleukin-2: lecithin:cholesteryl acyltransferase, lipoprotein lipase, and hepatic lipase deficiencies.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:5

    Topics: Apolipoprotein A-I; Apolipoproteins B; Apolipoproteins E; Chemical and Drug Induced Liver Injury; Ch

1997
Increased serum lipase with associated normoamylasemia in cancer patients.
    Clinical chemistry, 1998, Volume: 44, Issue:5

    Topics: Adenocarcinoma; alpha-Amylases; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Colorectal Neoplas

1998
Pancreatic toxicity after liposomal amphotericin B.
    Mycoses, 2002, Volume: 45, Issue:5-6

    Topics: Adolescent; Amphotericin B; Child; Child, Preschool; Female; Humans; Infant; Lipase; Liposomes; Male

2002
[Pancreatic enzymatic activity in the blood and urine in tumors of varying localization].
    Voprosy onkologii, 1978, Volume: 24, Issue:10

    Topics: Amylases; Enzyme Activation; Female; Humans; Lipase; Neoplasms; Pancreas; Pancreatic Diseases; Pepti

1978
Potential organ or tumor imaging agents. 32. A triglyceride ester of p-iodophenyl pentadecanoic acid as a potential hepatic imaging agent.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1992, Volume: 19, Issue:6

    Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Evaluation Studies as Topic; Female; Gamma Cameras;

1992
Plasma levels of pancreatic secretory trypsin inhibitor in relation to amylase and lipase in patients with acute and chronic renal failure.
    Nephron, 1988, Volume: 49, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Amylases; Humans; Kidney Failure, Chronic; Kidney Transplantation;

1988
The enzyme knife--a renewed direction for cancer therapy? Discussion paper.
    Journal of the Royal Society of Medicine, 1988, Volume: 81, Issue:5

    Topics: Amylases; Enzyme Therapy; Humans; Lipase; Neoplasms; Pancreatin; Trophoblasts

1988
Hepatic triglyceride lipase and lipoprotein lipase activities in post-heparin plasma of patients with various cancers.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:3

    Topics: Aged; Carcinoma, Hepatocellular; Cholesterol; Female; Humans; Lipase; Lipoprotein Lipase; Lipoprotei

1985
Effect of ethanol extract of cancer patients' serum on the vulnerability of lymphocytes to cortisol.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1988, Volume: 9, Issue:5

    Topics: Deoxyribonucleases; Ethanol; Humans; Hydrocortisone; Lipase; Lymphocytes; Neoplasms; Pronase; Ribonu

1988
[On the specificity of the tumor cell-characteristic agglutinins of "wheat germ lipase"].
    Die Naturwissenschaften, 1968, Volume: 55, Issue:7

    Topics: ABO Blood-Group System; Antibodies; Chitin; Hemagglutination Inhibition Tests; Lipase; Neoplasms; Ol

1968
[Demonstration of lectin receptor sites on the membrane of human tumoral cells].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Mar-01, Volume: 272, Issue:9

    Topics: Agglutination Tests; Astrocytoma; Avian Sarcoma Viruses; Binding Sites; Carcinoma; Cell Line; Cell M

1971
[Serum lipase determination within the scope of pancreas diagnosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Feb-15, Volume: 22, Issue:4

    Topics: Amylases; Biliary Tract Diseases; Clinical Enzyme Tests; Colorimetry; Fractures, Bone; Humans; Lipas

1967
Effect of artificially induced abacterial erysipelas and of chronic aseptic abscess on human and experimental neoplasms.
    Polish medical journal, 1968, Volume: 7, Issue:5

    Topics: Abscess; Adult; Aged; Amylases; Anemia; Animals; Breast Neoplasms; Child; Erysipelas; Eye Neoplasms;

1968
[A simple method for separation of accelerated sedimentation caused by tumor and inflammation].
    Deutsche medizinische Wochenschrift (1946), 1966, Oct-21, Volume: 91, Issue:42

    Topics: Blood Proteins; Blood Sedimentation; Diagnosis, Differential; Humans; Inflammation; Lipase; Neoplasm

1966