Page last updated: 2024-10-21

1-anilino-8-naphthalenesulfonate and Metabolic Syndrome

1-anilino-8-naphthalenesulfonate has been researched along with Metabolic Syndrome in 80 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"We previously demonstrated that children with Down syndrome (DS) exhibited a greater risk of steatosis than the general pediatric population."7.96PNPLA3 gene polymorphism is associated with liver steatosis in children with Down syndrome. ( Alisi, A; Crudele, A; Di Camillo, C; Mosca, A; Novelli, A; Raponi, M; Sartorelli, MR; Scoppola, V; Tarani, L; Valentini, D; Villani, A, 2020)
"Corchorus olitorius is effective as orlistat in preventing obesity, hyperlipidaemia, steatosis and insulin resistance."7.91Amelioration of experimental metabolic syndrome induced in rats by orlistat and Corchorus olitorius leaf extract; role of adipo/cytokines. ( Al-Zokeim, NI; El-Sers, DA; Gomaa, AA; Gomaa, MA, 2019)
" We hypothesized that dietary epigallocatechin-3-gallate (EGCG) could reverse metabolic syndrome in high fat-fed obese C57bl/6J mice, and that these effects were related to inhibition of pancreatic lipase (PL)."7.78(-)-Epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice. ( Grove, KA; Kennett, MJ; Lambert, JD; Sae-tan, S, 2012)
"Orlistat was well tolerated."6.71The ORLIstat and CArdiovascular risk profile in patients with metabolic syndrome and type 2 DIAbetes (ORLICARDIA) Study. ( Athyros, VG; Bousboulas, SH; Didangelos, TP; Dimitriou, KC; Karamanos, BG; Karamitsos, DT; Pappas, SI; Sambanis, CL; Spanou, EA; Thanopoulou, AK, 2004)
"Recently we have demonstrated that treatment with niacin raises adiponectin between 52% and 95% in patients with the metabolic syndrome."5.13Preferential increase in high-molecular weight adiponectin after niacin. ( Luley, C; Westphal, S, 2008)
"We previously demonstrated that children with Down syndrome (DS) exhibited a greater risk of steatosis than the general pediatric population."3.96PNPLA3 gene polymorphism is associated with liver steatosis in children with Down syndrome. ( Alisi, A; Crudele, A; Di Camillo, C; Mosca, A; Novelli, A; Raponi, M; Sartorelli, MR; Scoppola, V; Tarani, L; Valentini, D; Villani, A, 2020)
"Corchorus olitorius is effective as orlistat in preventing obesity, hyperlipidaemia, steatosis and insulin resistance."3.91Amelioration of experimental metabolic syndrome induced in rats by orlistat and Corchorus olitorius leaf extract; role of adipo/cytokines. ( Al-Zokeim, NI; El-Sers, DA; Gomaa, AA; Gomaa, MA, 2019)
" We hypothesized that dietary epigallocatechin-3-gallate (EGCG) could reverse metabolic syndrome in high fat-fed obese C57bl/6J mice, and that these effects were related to inhibition of pancreatic lipase (PL)."3.78(-)-Epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice. ( Grove, KA; Kennett, MJ; Lambert, JD; Sae-tan, S, 2012)
"MAFLD is closely intertwined with type 2 diabetes, obesity, dyslipidaemia, all linked to a rise in the risk of cardiovascular disease (CVDs)."2.72Nonalcoholic fatty liver disease or metabolic dysfunction-associated fatty liver disease diagnoses and cardiovascular diseases: From epidemiology to drug approaches. ( Corsini, A; Dongiovanni, P; Paolini, E; Ruscica, M; Sirtori, CR, 2021)
"Orlistat was well tolerated."2.71The ORLIstat and CArdiovascular risk profile in patients with metabolic syndrome and type 2 DIAbetes (ORLICARDIA) Study. ( Athyros, VG; Bousboulas, SH; Didangelos, TP; Dimitriou, KC; Karamanos, BG; Karamitsos, DT; Pappas, SI; Sambanis, CL; Spanou, EA; Thanopoulou, AK, 2004)
"Nonalcoholic fatty liver disease (NAFLD) affects around a quarter of the global population, paralleling worldwide increases in obesity and metabolic syndrome."2.66Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology. ( Eslam, M; George, J, 2020)
"Both individuals with type 1 diabetes mellitus (mean difference = -1."2.66Low serum amylase, lipase, and trypsin as biomarkers of metabolic disorders: A systematic review and meta-analysis. ( Cho, J; Ko, J; Petrov, MS, 2020)
"Furthermore, it also indicated that nonalcoholic steatohepatitis (NASH) was more frequently observed in G allele carriers among paediatric and adolescent NAFLD patients."2.66Effect of the patatin-like phospholipase domain containing 3 gene (PNPLA3) I148M polymorphism on the risk and severity of nonalcoholic fatty liver disease and metabolic syndromes: A meta-analysis of paediatric and adolescent individuals. ( Hua, W; Ji, C; Li, J; Rui, J; Shi, B; Xie, C; Yang, X; Zhao, Y, 2020)
"Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC)."2.66Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma. ( Goto, T; Hirotsu, Y; Kanda, T; Masuzaki, R; Moriyama, M; Omata, M, 2020)
"Non-obese NAFLD is common, particularly in South America and among people aged ≥45 years."2.66Epidemiology of nonalcoholic fatty liver disease in non-obese populations: Meta-analytic assessment of its prevalence, genetic, metabolic, and histological profiles. ( Fan, JG; Wong, VW; Zou, ZY, 2020)
"First described in 1980, nonalcoholic fatty liver disease (NAFLD) has become more common although the exact incidence and prevalence is unknown."2.58NAFLD-NASH: An Under-Recognized Epidemic. ( Faselis, C; Jennings, J; Yao, MD, 2018)
"Nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are highly prevalent, affecting approximately one-third of the US population."2.58Nonalcoholic Fatty Liver Disease and Metabolic Syndrome. ( Kim, D; Kim, WR; Touros, A, 2018)
"Posttransplant metabolic syndrome is a common occurrence that increases the risk of steatosis in the graft liver."2.58Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis in Liver Transplantation. ( Carter, D; Chang, C; Dieterich, DT, 2018)
"Nonalcoholic fatty liver disease is emerging as the most common cause of chronic liver disease worldwide."2.58Risk Factors for the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Genetics. ( Bernstein, DE; Lim, HW, 2018)
"Currently, the population prevalence of NAFLD in Asia is around 25%, like many Western countries."2.55New trends on obesity and NAFLD in Asia. ( Fan, JG; Kim, SU; Wong, VW, 2017)
"NAFLD is increasing in prevalence and is presently the second most frequent indication for liver transplantation."2.53Bidirectional Relationships and Disconnects between NAFLD and Features of the Metabolic Syndrome. ( Byrne, CD; Wainwright, P, 2016)
"Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common cause of liver disease in the United States."2.53The Prevalence and Pathobiology of Nonalcoholic Fatty Liver Disease in Patients of Different Races or Ethnicities. ( Gaglio, PJ; Kalia, HS, 2016)
"Non-alcoholic fatty liver disease (NAFLD) increases risk of mortality from liver and cardiovascular disease (CVD) and is the major cause of hepatocellular carcinoma (HCC), which may develop without cirrhosis."2.53Diagnosis of non-alcoholic fatty liver disease (NAFLD). ( Yki-Järvinen, H, 2016)
"Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and comprises a liver disease spectrum ranging from steatosis to nonalcoholic steatohepatitis (NASH) with risk of progression to liver cirrhosis and hepatocellular carcinoma (HCC)."2.52Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH. ( Halilbasic, E; Hofer, H; Kazemi-Shirazi, L; Kienbacher, C; Munda, P; Rechling, C; Trauner, M; Traussnigg, S, 2015)
"Nonalcoholic fatty liver disease (NAFLD) is increasingly being diagnosed worldwide and is strongly associated with the features of metabolic syndrome."2.52A Perspective on Metabolic Syndrome and Nonalcoholic Fatty Liver Disease. ( Byrne, CD; Targher, G, 2015)
"Half of people with NAFLD carry at least one variant (G) allele at rs738409 in the PNPLA3 gene, which is associated with high liver fat content."2.50Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome. ( Yki-Järvinen, H, 2014)
"The pathogenesis of type 2 diabetes involves both insulin resistance and defects in insulin secretion."2.46Liver fat in the pathogenesis of insulin resistance and type 2 diabetes. ( Yki-Järvinen, H, 2010)
"Patients with type 2 diabetes mellitus or the metabolic syndrome have a unique dyslipidemia characterized by hypertriglyceridemia; elevated blood levels of apolipoprotein B; small, dense low-density lipoprotein (LDL) cholesterol; and low levels of high-density lipoprotein (HDL) cholesterol, in particular HDL(2)-C."2.42Dyslipidemia in the metabolic syndrome and type 2 diabetes mellitus. ( Ayyobi, AF; Brunzell, JD, 2003)
"Non-alcoholic fatty liver disease (NAFLD) shares several risk factors with atherosclerosis, as it is associated with components of the metabolic syndrome."1.72Association of rs738409 Polymorphism in Adiponutrin Gene with Liver Steatosis and Atherosclerosis Risk Factors in Greek Children and Adolescents. ( Emmanouilidou-Fotoulaki, E; Fotoulaki, M; Kavga, M; Lambropoulos, AF; Papadopoulou-Legbelou, K; Sotiriadou, F; Stasinou, E, 2022)
"The histological spectrum of NAFLD was classified according to the NASH clinical research network scoring system."1.62Individualized Polygenic Risk Score Identifies NASH in the Eastern Asia Region: A Derivation and Validation Study. ( Byrne, CD; Chen, SD; Chen, YP; Gao, F; Kim, W; Lee, DH; Targher, G; Wang, XD; Wu, XX; Zheng, KI; Zheng, MH, 2021)
"NAFLD is multi-factorial in pathogenesis with some genetic predisposition."1.56The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease. ( Akkız, H; Delik, A; Dinçer, S, 2020)
"Non-alcoholic fatty liver disease (NAFLD) is commonly diagnosed in patients presenting with metabolic syndrome (MetS) and has been associated with single nucleotide polymorphisms of rs738409 in the patatin-like phospholipase domain containing 3 (PNPLA3) gene."1.56Association of metabolic syndrome and patatin-like phospholipase 3 - rs738409 gene variant in non-alcoholic fatty liver disease among a Chennai-based south Indian population. ( Karthick, R; Mohan, N; Narayanasamy, K; Panneerselvam, P; Prakash, R; Rajaram, M; Ramachandran, A, 2020)
"A total of 208 obese NAFLD patients without (n=125) and with prediabetes (n=83) were included."1.51PNPLA3 I148M Polymorphism in Patients with Nonalcoholic Fatty Liver Disease, Obesity and Prediabetes. ( Alexiev, A; Assyov, Y; Gateva, A; Ivanova, I; Ivanova, R; Ivanova-Boyanova, R; Kamenov, Z; Karamfilova, V; Mateva, L; Savov, A; Vlahova, Z; Yaneva, N, 2019)
"non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in the western world."1.51Comparative study of overweight and obese patients with nonalcoholic fatty liver disease. ( Aller, R; Antolín, B; Burgueño Gomez, B; de Luis Román, D; Durà, M; Fernández, N; Fernández-Rodríguez, C; García, C; Lorenzo, S; Pina, M; Sigüenza, R, 2019)
"One-hundred seventy-four NAFLD patients, who underwent liver biopsy for diagnostic work-up, were studied."1.46Low hepatic copper content and PNPLA3 polymorphism in non-alcoholic fatty liver disease in patients without metabolic syndrome. ( Aigner, E; Datz, C; Ferenci, P; Huber-Schönauer, U; Kienbacher, C; Stadlmayr, A; Stättermayer, AF; Steindl-Munda, P; Trauner, M; Traussnigg, S; Wrba, F, 2017)
"Obesity is associated with non-alcoholic fatty liver disease (NAFLD), and the patatin-like phospholipase 3 (PNPLA3) rs738409 (Ile148Met, C>G) gene polymorphism is one of the most important genetic determinants of NAFLD."1.42Patatin-like phospholipase 3 (rs738409) gene polymorphism is associated with increased liver enzymes in obese adolescents and metabolic syndrome in all ages. ( Aigner, E; Baumgartner, BG; Haybaeck, J; Lackner, C; Mangge, H; Prüller, F; Reininghaus, EZ; Schnedl, WJ; Stauber, R; Weghuber, D; Zelzer, S, 2015)
"The prevalence of GG genotype in NAFLD subjects was 20."1.40PNPLA3 gene polymorphism accounts for fatty liver in community subjects without metabolic syndrome. ( Chan, AW; Chan, HL; Chan, HY; Chan, RS; Chim, AM; Choi, PC; Chu, WC; Shen, J; Wong, GL; Wong, VW; Woo, J; Yeung, DK, 2014)
"Metabolic syndrome was defined according to ATPIII modified criteria."1.40Non-alcoholic fatty liver disease, metabolic syndrome and patatin-like phospholipase domain-containing protein3 gene variants. ( Angelico, F; Arca, M; Baratta, F; Brancorsini, M; D'Erasmo, L; Del Ben, M; Di Costanzo, A; Loffredo, L; Pastori, D; Pignatelli, P; Polimeni, L; Violi, F, 2014)
"Obesity is a complex metabolic disorder that often manifests with a strong genetic component in humans."1.39Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia. ( Hasan, G; Kumar, S; Metya, SK; Sadaf, S; Schwudke, D; Subramanian, M, 2013)
"The ECOPD was defined as worsening of symptoms requiring increased use of rescue medications and/or need for either systemic steroids or antibiotics or that led to emergency room visit or hospitalizations during 12 months follow-up."1.36Metabolic syndrome is associated with increased risk of acute exacerbation of COPD: a preliminary study. ( Erayman, Z; Gürsoy, A; Küpeli, E; Sahin, T; Ulasli, SS; Ulubay, G, 2010)
"(1) The treatment of obesity is based on calorie reduction and moderate physical activity."1.33Rimonabant: new drug. Obesity: loss of a few kilos, many questions. ( , 2006)

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (15.00)29.6817
2010's51 (63.75)24.3611
2020's17 (21.25)2.80

Authors

AuthorsStudies
Stasinou, E1
Emmanouilidou-Fotoulaki, E1
Kavga, M1
Sotiriadou, F1
Lambropoulos, AF1
Fotoulaki, M1
Papadopoulou-Legbelou, K1
Lai, HH1
Yeh, KY1
Hsu, HM1
Her, GM1
Klobučar, I2
Stadler, JT1
Klobučar, L2
Lechleitner, M2
Trbušić, M3
Pregartner, G3
Berghold, A3
Habisch, H2
Madl, T2
Marsche, G2
Frank, S3
Degoricija, V3
Mahdy, NE1
Abdel-Baki, PM1
El-Rashedy, AA1
Ibrahim, RM1
Antileo-Laurie, J1
Theoduloz, C1
Burgos-Edwards, A1
Jiménez-Aspee, F2
Márquez, K1
Fischer, M1
Schmeda-Hirschmann, G2
Eslam, M1
George, J1
Ko, J1
Cho, J1
Petrov, MS1
Karamfilova, V1
Gateva, A1
Assyov, Y1
Alexiev, A1
Savov, A1
Yaneva, N1
Ivanova, I1
Ivanova-Boyanova, R1
Ivanova, R1
Vlahova, Z1
Mateva, L1
Kamenov, Z1
Narayanasamy, K1
Karthick, R1
Panneerselvam, P1
Mohan, N1
Ramachandran, A1
Prakash, R1
Rajaram, M1
Li, J2
Hua, W1
Ji, C1
Rui, J1
Zhao, Y1
Xie, C1
Shi, B1
Yang, X1
Kanda, T1
Goto, T1
Hirotsu, Y1
Masuzaki, R1
Moriyama, M1
Omata, M1
Delik, A1
Akkız, H1
Dinçer, S1
Zou, ZY1
Wong, VW3
Fan, JG2
Cicolari, S1
Dacrema, M1
Tsetegho Sokeng, AJ1
Xiao, J1
Atchan Nwakiban, AP1
Di Giovanni, C1
Santarcangelo, C1
Magni, P2
Daglia, M1
Valentini, D1
Mosca, A1
Di Camillo, C1
Crudele, A2
Sartorelli, MR1
Scoppola, V1
Tarani, L1
Villani, A1
Raponi, M1
Novelli, A1
Alisi, A2
Dongiovanni, P2
Paolini, E1
Corsini, A1
Sirtori, CR1
Ruscica, M2
Gao, F1
Zheng, KI1
Chen, SD1
Lee, DH1
Wu, XX1
Wang, XD1
Targher, G2
Byrne, CD3
Chen, YP1
Kim, W1
Zheng, MH1
Potočnjak, I1
Terešak, SD1
Radulović, B1
Tiran, B1
Kim, SU1
Jennings, J1
Faselis, C1
Yao, MD1
Jakubczyk, A1
Karaś, M1
Złotek, U1
Szymanowska, U1
Kim, D1
Touros, A1
Kim, WR1
Carter, D1
Dieterich, DT1
Chang, C1
Lim, HW1
Bernstein, DE1
Tortora, R1
Rispo, A1
Imperatore, N1
Ferretti, F1
Nobili, V1
Miele, L1
Gerbino, N1
Caporaso, N1
Morisco, F1
Gomaa, AA1
El-Sers, DA1
Al-Zokeim, NI1
Gomaa, MA1
Aller, R1
Burgueño Gomez, B1
Sigüenza, R1
Fernández-Rodríguez, C1
Fernández, N1
Antolín, B1
Durà, M1
Pina, M1
Lorenzo, S1
García, C1
de Luis Román, D1
Chen, Z1
Zhang, D1
Guo, JJ1
Tao, W1
Gong, RX1
Yao, L1
Zhang, XL1
Cao, WG1
Gong, L1
Liu, S1
Zhang, Y2
Zhang, C2
Tian, M1
Lu, H1
Bu, P1
Yang, J1
Ouyang, C1
Jiang, X1
Wu, J1
Min, Q1
Zhang, W1
Subramanian, M1
Metya, SK1
Sadaf, S1
Kumar, S1
Schwudke, D1
Hasan, G1
Dalar, A1
Türker, M1
Zabaras, D1
Konczak, I2
Hyysalo, J1
Männistö, VT1
Zhou, Y1
Arola, J1
Kärjä, V1
Leivonen, M1
Juuti, A1
Jaser, N1
Lallukka, S1
Käkelä, P1
Venesmaa, S1
Simonen, M1
Saltevo, J1
Moilanen, L1
Korpi-Hyövalti, E1
Keinänen-Kiukaanniemi, S1
Oksa, H1
Orho-Melander, M2
Valenti, L2
Fargion, S2
Pihlajamäki, J1
Peltonen, M2
Yki-Järvinen, H5
Shen, J1
Wong, GL1
Chan, HL1
Chan, HY1
Yeung, DK1
Chan, RS1
Chim, AM1
Chan, AW1
Choi, PC1
Woo, J1
Chu, WC1
Miksztowicz, V1
Schreier, L1
McCoy, M1
Lucero, D1
Fassio, E1
Billheimer, J1
Rader, DJ2
Berg, G1
Caminhotto, Rde O1
Campaña, AB1
Lima, FB1
Kitamoto, A1
Kitamoto, T1
Nakamura, T1
Ogawa, Y1
Yoneda, M1
Hyogo, H1
Ochi, H1
Mizusawa, S1
Ueno, T1
Nakao, K1
Sekine, A1
Chayama, K1
Nakajima, A1
Hotta, K1
Ueno, H1
Nakazato, M1
Rametta, R1
Macchi, C1
Fracanzani, AL1
Steffani, L1
Del Ben, M1
Polimeni, L1
Brancorsini, M1
Di Costanzo, A1
D'Erasmo, L1
Baratta, F1
Loffredo, L1
Pastori, D1
Pignatelli, P1
Violi, F1
Arca, M1
Angelico, F1
Shirakawa, T1
Nakajima, K1
Yatsuzuka, S1
Shimomura, Y1
Kobayashi, J1
Machida, T1
Sumino, H1
Murakami, M1
Villiger, A1
Sala, F1
Suter, A1
Butterweck, V1
Mangge, H2
Baumgartner, BG1
Zelzer, S1
Prüller, F1
Schnedl, WJ1
Reininghaus, EZ1
Haybaeck, J1
Lackner, C1
Stauber, R1
Aigner, E2
Weghuber, D1
Traussnigg, S2
Kienbacher, C2
Halilbasic, E1
Rechling, C1
Kazemi-Shirazi, L1
Hofer, H1
Munda, P1
Trauner, M2
Baumgartner, B1
Schnedl, W1
Liu, Z1
Que, S1
Zhou, L1
Zheng, S1
Wainwright, P1
Kalia, HS1
Gaglio, PJ1
Andrés-Blasco, I1
Vinué, Á1
Herrero-Cervera, A1
Martínez-Hervás, S1
Nuñez, L1
Piqueras, L1
Ascaso, JF1
Sanz, MJ1
Burks, DJ1
González-Navarro, H1
Christiansen, MK1
Jensen, JM1
Brøndberg, AK1
Bøtker, HE1
Jensen, HK1
Orqueda, ME1
Rivas, M1
Zampini, IC1
Alberto, MR1
Torres, S1
Cuello, S1
Sayago, J1
Thomas-Valdes, S1
Isla, MI1
Stättermayer, AF1
Huber-Schönauer, U1
Steindl-Munda, P1
Stadlmayr, A1
Wrba, F1
Datz, C1
Ferenci, P1
Kotronen, A1
Hakkarainen, A1
Sevastianova, K1
Bergholm, R1
Johansson, LM1
Lundbom, N1
Rissanen, A1
Ridderstråle, M1
Groop, L1
Kohlwein, SD1
Zhou, YJ1
Li, YY1
Nie, YQ1
Yang, H1
Zhan, Q1
Huang, J1
Shi, SL1
Lai, XB1
Huang, HL1
Speliotes, EK1
Butler, JL1
Palmer, CD1
Voight, BF1
Hirschhorn, JN1
Ko, JS1
Küpeli, E1
Ulubay, G1
Ulasli, SS1
Sahin, T1
Erayman, Z1
Gürsoy, A1
Grove, KA1
Sae-tan, S1
Kennett, MJ1
Lambert, JD1
Ackerman, D1
Gems, D1
Ampuero, J1
Romero-Gómez, M1
van Hees, AM1
Jocken, JW1
Essers, Y1
Roche, HM1
Saris, WH1
Blaak, EE1
Krarup, NT1
Grarup, N1
Banasik, K1
Friedrichsen, M1
Færch, K1
Sandholt, CH1
Jørgensen, T1
Poulsen, P1
Witte, DR1
Vaag, A1
Sørensen, T1
Pedersen, O1
Hansen, T1
Li, Q1
Qu, HQ1
Rentfro, AR1
Grove, ML1
Mirza, S1
Lu, Y1
Hanis, CL1
Fallon, MB1
Boerwinkle, E1
Fisher-Hoch, SP1
McCormick, JB1
Sakulnarmrat, K1
Brunzell, JD1
Ayyobi, AF1
Didangelos, TP1
Thanopoulou, AK1
Bousboulas, SH1
Sambanis, CL1
Athyros, VG1
Spanou, EA1
Dimitriou, KC1
Pappas, SI1
Karamanos, BG1
Karamitsos, DT1
Hansel, B1
Kontush, A1
Twickler, MT1
Stancáková, A1
Baldaufová, L1
Javorský, M1
Kozárová, M1
Salagovic, J1
Tkác, I1
Badellino, KO1
Wolfe, ML1
Reilly, MP1
Kusunoki, J1
Kanatani, A1
Moller, DE1
Langin, D1
Lamarche, B1
Paradis, ME1
Köhler, J1
Wünsch, B1
Westphal, S1
Luley, C1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Non Invasive Evaluation of Liver Fibrosis and Steatosis in Type 2 Diabetic Patient in Assiut University Hospitals[NCT05605717]60 participants (Anticipated)Observational2022-11-01Not yet recruiting
Clinical Study on the Value of Quantitative MRI Imaging in Diffuse Liver Diseases[NCT04626492]150 participants (Anticipated)Observational [Patient Registry]2020-08-01Recruiting
Effect of Intermittent Calorie Restriction on Metabolic Dysfunction-Associated Steatotic Liver Disease Patients With Abnormal Glucose Metabolism[NCT04283942]60 participants (Actual)Interventional2020-07-30Completed
Study for the Investigation of New Individual Risk Profiles and Therapeutic Strategies in Obesity Related Cardiovascular and Metabolic Disorders.[NCT00482924]1,500 participants (Anticipated)Observational2003-01-31Recruiting
Optimizing the Beneficial Health Effects of Exercise for Diabetes: Focus on the Liver![NCT01317576]81 participants (Actual)Interventional2011-03-31Completed
Study of Metabolism Influence in Human Alcoholic Liver Disease[NCT01122797]658 participants (Actual)Observational2003-01-31Completed
LIPGENE Dietary Intervention Study[NCT00429195]480 participants Interventional2004-02-29Completed
A Randomised Controlled International Multicentre Study Evaluating Changes in Metabolic Syndrome in Smokers With Type 2 Diabetes Mellitus After Switching From Tobacco Cigarettes to Combustion-Free Nicotine Delivery Systems: DIASMOKE Study[NCT04231838]576 participants (Anticipated)Interventional2021-09-27Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

29 reviews available for 1-anilino-8-naphthalenesulfonate and Metabolic Syndrome

ArticleYear
Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology.
    Nature reviews. Gastroenterology & hepatology, 2020, Volume: 17, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Acyltransferases; Adaptor Proteins, Signal Transducing; Carcinoma,

2020
Low serum amylase, lipase, and trypsin as biomarkers of metabolic disorders: A systematic review and meta-analysis.
    Diabetes research and clinical practice, 2020, Volume: 159

    Topics: Amylases; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lipase; Metaboli

2020
Effect of the patatin-like phospholipase domain containing 3 gene (PNPLA3) I148M polymorphism on the risk and severity of nonalcoholic fatty liver disease and metabolic syndromes: A meta-analysis of paediatric and adolescent individuals.
    Pediatric obesity, 2020, Volume: 15, Issue:6

    Topics: Adolescent; Child; Female; Genetic Predisposition to Disease; Humans; Lipase; Male; Membrane Protein

2020
Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma.
    International journal of molecular sciences, 2020, Feb-23, Volume: 21, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Apoptosis; Carcinoma, Hepatocellular; Diet, High-Fat; Dis

2020
Epidemiology of nonalcoholic fatty liver disease in non-obese populations: Meta-analytic assessment of its prevalence, genetic, metabolic, and histological profiles.
    Journal of digestive diseases, 2020, Volume: 21, Issue:7

    Topics: Diabetes Mellitus; Humans; Lipase; Membrane Proteins; Metabolic Syndrome; Non-alcoholic Fatty Liver

2020
Nonalcoholic fatty liver disease or metabolic dysfunction-associated fatty liver disease diagnoses and cardiovascular diseases: From epidemiology to drug approaches.
    European journal of clinical investigation, 2021, Volume: 51, Issue:7

    Topics: Acyltransferases; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dysli

2021
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
New trends on obesity and NAFLD in Asia.
    Journal of hepatology, 2017, Volume: 67, Issue:4

    Topics: Asia; Body Mass Index; Diet; Genetic Predisposition to Disease; Hepatitis B, Chronic; Humans; Incide

2017
NAFLD-NASH: An Under-Recognized Epidemic.
    Current vascular pharmacology, 2018, Volume: 16, Issue:3

    Topics: Coronary Artery Disease; Epidemics; Female; Genetic Predisposition to Disease; Global Health; Hispan

2018
Nonalcoholic Fatty Liver Disease and Metabolic Syndrome.
    Clinics in liver disease, 2018, Volume: 22, Issue:1

    Topics: Dyslipidemias; Humans; Hyperglycemia; Hypertension; Lipase; Membrane Proteins; Metabolic Syndrome; N

2018
Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis in Liver Transplantation.
    Clinics in liver disease, 2018, Volume: 22, Issue:1

    Topics: Cardiovascular Diseases; Diabetes Complications; Humans; Kidney Diseases; Lipase; Liver Transplantat

2018
Risk Factors for the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Genetics.
    Clinics in liver disease, 2018, Volume: 22, Issue:1

    Topics: Acyltransferases; Asian People; Black or African American; Diabetes Mellitus, Type 2; Female; Hispan

2018
Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome.
    The lancet. Diabetes & endocrinology, 2014, Volume: 2, Issue:11

    Topics: Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Metabolic S

2014
[Cutting-edge of medicine; the prospects of novel anti-obesity drugs].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Mar-10, Volume: 103, Issue:3

    Topics: Anti-Obesity Agents; Appetite; Appetite Depressants; Benzazepines; Benzoxazines; Bupropion; Clinical

2014
A Perspective on Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.
    Metabolic syndrome and related disorders, 2015, Volume: 13, Issue:6

    Topics: Biomarkers; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Genetic Variation; Humans;

2015
Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4

    Topics: Anticholesteremic Agents; Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Disease Progre

2015
Bidirectional Relationships and Disconnects between NAFLD and Features of the Metabolic Syndrome.
    International journal of molecular sciences, 2016, Mar-11, Volume: 17, Issue:3

    Topics: Animals; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Insulin Res

2016
The Prevalence and Pathobiology of Nonalcoholic Fatty Liver Disease in Patients of Different Races or Ethnicities.
    Clinics in liver disease, 2016, Volume: 20, Issue:2

    Topics: Black or African American; Hispanic or Latino; Humans; Lipase; Membrane Proteins; Metabolic Syndrome

2016
Diagnosis of non-alcoholic fatty liver disease (NAFLD).
    Diabetologia, 2016, Volume: 59, Issue:6

    Topics: Alanine Transaminase; Genotype; Humans; Lipase; Membrane Proteins; Metabolic Syndrome; Non-alcoholic

2016
Obese and anorexic yeasts: experimental models to understand the metabolic syndrome and lipotoxicity.
    Biochimica et biophysica acta, 2010, Volume: 1801, Issue:3

    Topics: Animals; Anorexia; Fatty Acids; Humans; Lipase; Lipid Peroxidation; Metabolic Syndrome; Models, Biol

2010
Liver fat in the pathogenesis of insulin resistance and type 2 diabetes.
    Digestive diseases (Basel, Switzerland), 2010, Volume: 28, Issue:1

    Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Fatty Liver; Glucose; Humans; Insulin; Insulin Resistance

2010
[Nonalcoholic fatty liver disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2010, Volume: 56, Issue:1

    Topics: Diet; Fatty Liver; Humans; Inflammation Mediators; Insulin Resistance; Lipase; Membrane Proteins; Me

2010
The mystery of C. elegans aging: an emerging role for fat. Distant parallels between C. elegans aging and metabolic syndrome?
    BioEssays : news and reviews in molecular, cellular and developmental biology, 2012, Volume: 34, Issue:6

    Topics: Aging; Animals; Caenorhabditis elegans; Homeostasis; Lipase; Lipids; Longevity; Metabolic Syndrome;

2012
[Influence of non-alcoholic fatty liver disease on cardiovascular disease].
    Gastroenterologia y hepatologia, 2012, Volume: 35, Issue:8

    Topics: Apolipoprotein C-III; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Chol

2012
The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Body Mass Index; Case-Control Studies; Cholesterol; Denmark; Dyslipidemias; Fasting; Female; Gene Fr

2012
Dyslipidemia in the metabolic syndrome and type 2 diabetes mellitus.
    The American journal of medicine, 2003, Dec-08, Volume: 115 Suppl 8A

    Topics: Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus, Type 2; Humans; Hype

2003
High-density lipoprotein as a key component in the prevention of premature atherosclerotic disease in the insulin resistance syndrome.
    Seminars in vascular medicine, 2004, Volume: 4, Issue:2

    Topics: Apolipoproteins B; Arteriosclerosis; Diabetes Mellitus, Type 2; Esterification; Homeostasis; Humans;

2004
Modulation of fatty acid metabolism as a potential approach to the treatment of obesity and the metabolic syndrome.
    Endocrine, 2006, Volume: 29, Issue:1

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Diacylglycerol

2006
Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome.
    Pharmacological research, 2006, Volume: 53, Issue:6

    Topics: Adipose Tissue; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lipase; Lipolysis; Metabolic Synd

2006
Endothelial lipase and the metabolic syndrome.
    Current opinion in lipidology, 2007, Volume: 18, Issue:3

    Topics: Animals; Cholesterol Ester Transfer Proteins; Humans; Hypertension; Inflammation; Lipase; Lipoprotei

2007

Trials

4 trials available for 1-anilino-8-naphthalenesulfonate and Metabolic Syndrome

ArticleYear
Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:10

    Topics: Adiposity; Aged; Dietary Carbohydrates; Dietary Fats; Female; Humans; Insulin Resistance; Lipase; Ma

2012
PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population.
    Clinical and investigative medicine. Medecine clinique et experimentale, 2012, Aug-04, Volume: 35, Issue:4

    Topics: Adult; Age Factors; Alanine Transaminase; Aspartate Aminotransferases; Female; Genotype; Humans; Lip

2012
The ORLIstat and CArdiovascular risk profile in patients with metabolic syndrome and type 2 DIAbetes (ORLICARDIA) Study.
    Current medical research and opinion, 2004, Volume: 20, Issue:9

    Topics: Anti-Obesity Agents; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet, Reduci

2004
Preferential increase in high-molecular weight adiponectin after niacin.
    Atherosclerosis, 2008, Volume: 198, Issue:1

    Topics: Adiponectin; Cholesterol, HDL; Cholesterol, LDL; Delayed-Action Preparations; Fatty Acids, Nonesteri

2008

Other Studies

47 other studies available for 1-anilino-8-naphthalenesulfonate and Metabolic Syndrome

ArticleYear
Association of rs738409 Polymorphism in Adiponutrin Gene with Liver Steatosis and Atherosclerosis Risk Factors in Greek Children and Adolescents.
    Nutrients, 2022, Aug-23, Volume: 14, Issue:17

    Topics: Acyltransferases; Adolescent; Atherosclerosis; Child; Genetic Predisposition to Disease; Genotype; G

2022
Deficiency of Adipose Triglyceride Lipase Induces Metabolic Syndrome and Cardiomyopathy in Zebrafish.
    International journal of molecular sciences, 2022, Dec-21, Volume: 24, Issue:1

    Topics: Adipose Tissue; Animals; Cardiomyopathies; CRISPR-Associated Protein 9; Lipase; Lipolysis; Metabolic

2022
Associations between Endothelial Lipase, High-Density Lipoprotein, and Endothelial Function Differ in Healthy Volunteers and Metabolic Syndrome Patients.
    International journal of molecular sciences, 2023, Jan-20, Volume: 24, Issue:3

    Topics: Apolipoprotein A-I; Cholesterol; Cholesterol, HDL; Healthy Volunteers; Humans; Lipase; Lipoproteins,

2023
Modulatory Effect of Pyrus pyrifolia Fruit and its Phenolics on Key Enzymes against Metabolic Syndrome: Bioassay-Guided Approach, HPLC Analysis, and In Silico Study.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2023, Volume: 78, Issue:2

    Topics: alpha-Amylases; alpha-Glucosidases; Antioxidants; Chromatography, High Pressure Liquid; Fruit; Lipas

2023
Associations between Endothelial Lipase and Apolipoprotein B-Containing Lipoproteins Differ in Healthy Volunteers and Metabolic Syndrome Patients.
    International journal of molecular sciences, 2023, Jun-26, Volume: 24, Issue:13

    Topics: Apolipoproteins B; Cholesterol; Healthy Volunteers; Humans; Lipase; Lipoproteins; Lipoproteins, LDL;

2023
Antioxidant capacity and inhibition of metabolic syndrome-associated enzymes by Cryptocarya alba fruits.
    Food research international (Ottawa, Ont.), 2023, Volume: 173, Issue:Pt 2

    Topics: alpha-Glucosidases; Antioxidants; Catechin; Cryptocarya; Fruit; Lipase; Metabolic Syndrome; Phenols;

2023
PNPLA3 I148M Polymorphism in Patients with Nonalcoholic Fatty Liver Disease, Obesity and Prediabetes.
    Journal of gastrointestinal and liver diseases : JGLD, 2019, Dec-09, Volume: 28, Issue:4

    Topics: Adult; Aged; Anthropometry; Female; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Mal

2019
Association of metabolic syndrome and patatin-like phospholipase 3 - rs738409 gene variant in non-alcoholic fatty liver disease among a Chennai-based south Indian population.
    The journal of gene medicine, 2020, Volume: 22, Issue:4

    Topics: Adult; Aged; Alleles; Biomarkers; Case-Control Studies; Disease Susceptibility; Female; Genetic Pred

2020
The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020, Volume: 39, Issue:1

    Topics: Carcinoma, Hepatocellular; Deception; Humans; Lipase; Liver Neoplasms; Membrane Proteins; Metabolic

2020
Hydromethanolic Extracts from
    Molecules (Basel, Switzerland), 2020, Jun-21, Volume: 25, Issue:12

    Topics: Adansonia; Adipocytes; alpha-Amylases; Angiotensin-Converting Enzyme Inhibitors; Cell Differentiatio

2020
PNPLA3 gene polymorphism is associated with liver steatosis in children with Down syndrome.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2020, 08-28, Volume: 30, Issue:9

    Topics: Adiponectin; Adolescent; Age Factors; Biomarkers; Blood Glucose; Child; Child, Preschool; Down Syndr

2020
Individualized Polygenic Risk Score Identifies NASH in the Eastern Asia Region: A Derivation and Validation Study.
    Clinical and translational gastroenterology, 2021, 03-10, Volume: 12, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Biopsy; China; Cross-Sectional Studies; Female; Genetic Pre

2021
Metabolic Syndrome Modulates Association between Endothelial Lipase and Lipid/Lipoprotein Plasma Levels in Acute Heart Failure Patients.
    Scientific reports, 2017, 04-26, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Female; Heart Failure; Humans; Lipase; Lipids; Lipoproteins; Male; Metaboli

2017
Identification of potential inhibitory peptides of enzymes involved in the metabolic syndrome obtained by simulated gastrointestinal digestion of fermented bean (Phaseolus vulgaris L.) seeds.
    Food research international (Ottawa, Ont.), 2017, Volume: 100, Issue:Pt 1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Digestion; Fermentation; Humans; Lipase; Metaboli

2017
PNPLA3 rs738409 Polymorphism Predicts Development and Severity of Hepatic Steatosis but Not Metabolic Syndrome in Celiac Disease.
    Nutrients, 2018, Sep-05, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Alleles; Celiac Disease; Diet, Gluten-Free; Fatty Liver; Female; Genetic Predispo

2018
Amelioration of experimental metabolic syndrome induced in rats by orlistat and Corchorus olitorius leaf extract; role of adipo/cytokines.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:2

    Topics: Adiponectin; Animals; Anti-Obesity Agents; Corchorus; Cytokines; Diet, High-Fat; Hyperlipidemias; In

2019
Comparative study of overweight and obese patients with nonalcoholic fatty liver disease.
    Revista espanola de enfermedades digestivas, 2019, Volume: 111, Issue:4

    Topics: Adiponectin; Adult; Analysis of Variance; Biopsy, Needle; Body Mass Index; Cross-Sectional Studies;

2019
Active Components, Antioxidant, Inhibition on Metabolic Syndrome Related Enzymes, and Monthly Variations in Mature Leaf Hawk Tea.
    Molecules (Basel, Switzerland), 2019, Feb-13, Volume: 24, Issue:4

    Topics: alpha-Glucosidases; Antioxidants; China; Drugs, Chinese Herbal; Flavonoids; Glycoside Hydrolase Inhi

2019
Adipose HuR protects against diet-induced obesity and insulin resistance.
    Nature communications, 2019, 05-30, Volume: 10, Issue:1

    Topics: Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Cell Enlargement; Diet, High-Fat; ELAV-L

2019
Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia.
    Disease models & mechanisms, 2013, Volume: 6, Issue:3

    Topics: Adiposity; Animals; Appetite; Body Weight; Drosophila melanogaster; Drosophila Proteins; Fatty Acids

2013
Phenolic composition, antioxidant and enzyme inhibitory activities of Eryngium bornmuelleri leaf.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2014, Volume: 69, Issue:1

    Topics: alpha-Amylases; Antioxidants; Enzyme Inhibitors; Eryngium; Glycoside Hydrolase Inhibitors; Humans; L

2014
A population-based study on the prevalence of NASH using scores validated against liver histology.
    Journal of hepatology, 2014, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Biopsy; Cohort Studies; Diabetes Mellitus, Type 2; Female; Finland; Humans;

2014
PNPLA3 gene polymorphism accounts for fatty liver in community subjects without metabolic syndrome.
    Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:5

    Topics: Adult; Diet; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Metabolic Syndrome; Middl

2014
Role of SN1 lipases on plasma lipids in metabolic syndrome and obesity.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:3

    Topics: Adult; Apolipoprotein A-I; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids, Noneste

2014
[Lipolysis inhibition as therapeutic target in the metabolic syndrome].
    Arquivos brasileiros de endocrinologia e metabologia, 2014, Volume: 58, Issue:1

    Topics: Adipocytes; Adipose Tissue; Enzyme Activation; Humans; Insulin Resistance; Lipase; Lipolysis; Metabo

2014
Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits.
    Endocrine journal, 2014, Volume: 61, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adult; Alleles; Case-Control Studies; Female; Gene Frequency;

2014
Hepatic steatosis and PNPLA3 I148M variant are associated with serum Fetuin-A independently of insulin resistance.
    European journal of clinical investigation, 2014, Volume: 44, Issue:7

    Topics: Adiponectin; alpha-2-HS-Glycoprotein; Cross-Sectional Studies; Fatty Acids, Nonesterified; Fatty Liv

2014
Non-alcoholic fatty liver disease, metabolic syndrome and patatin-like phospholipase domain-containing protein3 gene variants.
    European journal of internal medicine, 2014, Volume: 25, Issue:6

    Topics: Adult; Aged; Cardiovascular Diseases; Cohort Studies; Female; Genetic Predisposition to Disease; Hum

2014
The role of circulating lipoprotein lipase and adiponectin on the particle size of remnant lipoproteins in patients with diabetes mellitus and metabolic syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 2015, Feb-02, Volume: 440

    Topics: Adiponectin; Adult; Case-Control Studies; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2;

2015
In vitro inhibitory potential of Cynara scolymus, Silybum marianum, Taraxacum officinale, and Peumus boldus on key enzymes relevant to metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Jan-15, Volume: 22, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Cynara scolymus; Enzyme Inhibitors; Flavonoids; Glycoside

2015
Patatin-like phospholipase 3 (rs738409) gene polymorphism is associated with increased liver enzymes in obese adolescents and metabolic syndrome in all ages.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Aged; Alleles; Case-Control Studies; Child; Female; Genotype; Heterozygote; Human

2015
Letter: PNPLA3, metabolic syndrome and NAFLD status in obese subjects--authors' reply.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:5

    Topics: Female; Humans; Lipase; Male; Membrane Proteins; Metabolic Syndrome; Non-alcoholic Fatty Liver Disea

2015
Letter: PNPLA3, metabolic syndrome and NAFLD status in obese subjects.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:5

    Topics: Female; Humans; Lipase; Male; Membrane Proteins; Metabolic Syndrome; Non-alcoholic Fatty Liver Disea

2015
Hepatic lipase inactivation decreases atherosclerosis in insulin resistance by reducing LIGHT/Lymphotoxin β-Receptor pathway.
    Thrombosis and haemostasis, 2016, 08-01, Volume: 116, Issue:2

    Topics: Animals; Atherosclerosis; Diet, Atherogenic; Disease Models, Animal; Humans; Inflammation Mediators;

2016
Cardiovascular risk factor control is insufficient in young patients with coronary artery disease.
    Vascular health and risk management, 2016, Volume: 12

    Topics: Adult; Age of Onset; Antihypertensive Agents; Biomarkers; Blood Pressure; Body Mass Index; Cholester

2016
Chemical and functional characterization of seed, pulp and skin powder from chilto (Solanum betaceum), an Argentine native fruit. Phenolic fractions affect key enzymes involved in metabolic syndrome and oxidative stress.
    Food chemistry, 2017, Feb-01, Volume: 216

    Topics: alpha-Amylases; alpha-Glucosidases; Antioxidants; Argentina; Ascorbic Acid; Carotenoids; Cinnamates;

2017
Low hepatic copper content and PNPLA3 polymorphism in non-alcoholic fatty liver disease in patients without metabolic syndrome.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2017, Volume: 39

    Topics: Adult; Copper; Female; Humans; Lipase; Liver; Male; Membrane Proteins; Metabolic Syndrome; Middle Ag

2017
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn

2009
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn

2009
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn

2009
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn

2009
Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:4

    Topics: Adiponectin; Adult; Aged; Asian People; Case-Control Studies; Chi-Square Distribution; China; Fatty

2010
PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:3

    Topics: Adult; Alleles; Biopsy; Case-Control Studies; Disease Progression; Fatty Liver; Female; Genetic Pred

2010
Metabolic syndrome is associated with increased risk of acute exacerbation of COPD: a preliminary study.
    Endocrine, 2010, Volume: 38, Issue:1

    Topics: Acute Disease; Aged; C-Reactive Protein; Case-Control Studies; Female; Humans; Inflammation; Lipase;

2010
(-)-Epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:11

    Topics: Animals; Antioxidants; Body Weight; Catechin; Diet, High-Fat; Feces; Lipase; Lipids; Male; Metabolic

2012
Composition of native Australian herbs polyphenolic-rich fractions and in vitro inhibitory activities against key enzymes relevant to metabolic syndrome.
    Food chemistry, 2012, Sep-15, Volume: 134, Issue:2

    Topics: alpha-Glucosidases; Animals; Australia; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; K

2012
Effect of gene polymorphisms on lipoprotein levels in patients with dyslipidemia of metabolic syndrome.
    Physiological research, 2006, Volume: 55, Issue:5

    Topics: Aged; Apolipoprotein C-III; Apolipoproteins B; Cholesterol; Cholesterol Ester Transfer Proteins; Cho

2006
Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis.
    PLoS medicine, 2006, Volume: 3, Issue:2

    Topics: Adult; Aged; Anticoagulants; Cholesterol, HDL; Coronary Artery Disease; Cross-Sectional Studies; Enz

2006
Rimonabant: new drug. Obesity: loss of a few kilos, many questions.
    Prescrire international, 2006, Volume: 15, Issue:84

    Topics: Anti-Obesity Agents; Cholesterol, HDL; Diet, Reducing; Double-Blind Method; Drug Approval; Europe; E

2006
The allosteric modulation of lipases and its possible biological relevance.
    Theoretical biology & medical modelling, 2007, Sep-07, Volume: 4

    Topics: Adipose Tissue; Allosteric Regulation; Animals; Burkholderia cepacia; Computer Simulation; Energy Me

2007