1-anilino-8-naphthalenesulfonate has been researched along with Liver Steatosis in 262 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study shows that both sibutramine-induced and orlistat-induced weight losses result in reduction of insulin resistance, and improvements in biochemical markers and US findings of NASH." | 9.10 | The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis. ( Karaoglanoglu, M; Kilic, FB; Nazligul, Y; Sabuncu, T; Ucar, E, 2003) |
| "Resveratrol (RES) has the ability to ameliorate nonalcoholic fatty liver disease (NAFLD) and the mechanism remains unclear." | 7.88 | Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption. ( Abdel-Aleem, GA; Khaleel, EF; Mostafa, DG, 2018) |
| "Osthole was found to have therapeutic effects on fatty milk-induced rat fatty liver; the mechanisms might be associated with its anti-oxidation and the elevation of the activities of LPL and HL." | 7.74 | Therapeutic effect of osthole on hyperlipidemic fatty liver in rats. ( Gu, ZL; Xie, ML; Zhang, Y; Zhu, LJ, 2007) |
| "Fatty liver was induced in Wistar rats by orotic acid and the recovery process was studied by enzyme histochemical staining for non specific esterase, lipase and by ultrastructural investigation." | 7.67 | Enzyme histochemical and ultrastructural approach in orotic acid-induced fatty liver and their recovery process in Wistar rats. ( Murakoshi, M; Suemizu, H; Watanabe, K, 1988) |
| "Obese NAFLD model was established in Sprague-Dawley rats by 8-week HFD feeding." | 5.40 | Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats. ( Guo, F; Li, S; Li, X; Li, Y; Liao, X; Meng, F; Meng, M; Sun, C; Sun, Z; Wang, Y, 2014) |
| "The present study shows that both sibutramine-induced and orlistat-induced weight losses result in reduction of insulin resistance, and improvements in biochemical markers and US findings of NASH." | 5.10 | The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis. ( Karaoglanoglu, M; Kilic, FB; Nazligul, Y; Sabuncu, T; Ucar, E, 2003) |
| "Resveratrol (RES) has the ability to ameliorate nonalcoholic fatty liver disease (NAFLD) and the mechanism remains unclear." | 3.88 | Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption. ( Abdel-Aleem, GA; Khaleel, EF; Mostafa, DG, 2018) |
| "05) with serum levels of alanine aminotransferase (ALT), asparate aminotransferase (AST), glucose, fibrinogen, and insulin-dependent diabetes mellitus, homeostasis model assessment-insulin resistance, and presence of NASH." | 3.79 | Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity. ( Charlton, MR; Gawrieh, S; Guichelaar, MM; Krishnan, A; Malinchoc, M; Olivier, M; Sanderson, S; Sarr, M; Swain, JM; Viker, K; Watt, KD, 2013) |
| "Osthole was found to have therapeutic effects on fatty milk-induced rat fatty liver; the mechanisms might be associated with its anti-oxidation and the elevation of the activities of LPL and HL." | 3.74 | Therapeutic effect of osthole on hyperlipidemic fatty liver in rats. ( Gu, ZL; Xie, ML; Zhang, Y; Zhu, LJ, 2007) |
| "Fatty liver was induced in Wistar rats by orotic acid and the recovery process was studied by enzyme histochemical staining for non specific esterase, lipase and by ultrastructural investigation." | 3.67 | Enzyme histochemical and ultrastructural approach in orotic acid-induced fatty liver and their recovery process in Wistar rats. ( Murakoshi, M; Suemizu, H; Watanabe, K, 1988) |
| "The penetration of Rhizopus arrhizus lipase into ethionine fatty livers was examined histochemically." | 3.66 | Ultracytochemical observations on intracytoplasmic lipids by enzymic digestive methods: histochemical trials. ( Morii, S, 1983) |
| "NAFLD was identified by liver ultrasonography." | 2.79 | Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals. ( Chang, MH; Chang, PF; Lin, YC; Ni, YH, 2014) |
| "We examined the genetic background of nonalcoholic fatty liver disease (NAFLD) in the Japanese population, by performing a genome-wide association study (GWAS)." | 2.78 | Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan. ( Chayama, K; Hotta, K; Hyogo, H; Kitamoto, A; Kitamoto, T; Mizusawa, S; Nakajima, A; Nakamura, T; Nakao, K; Ochi, H; Sekine, A; Teranishi, H; Ueno, T; Yoneda, M, 2013) |
| "NAFLD was determined by ultrasonography." | 2.78 | A common variant in the peroxisome proliferator-activated receptor-γ coactivator-1α gene is associated with nonalcoholic fatty liver disease in obese children. ( Chang, MH; Chang, PF; Lin, YC; Ni, YH, 2013) |
| "Sixty children with NAFLD were randomized in equal numbers to DHA 250 mg/day, DHA 500 mg/day or placebo." | 2.78 | The I148M variant of PNPLA3 reduces the response to docosahexaenoic acid in children with non-alcoholic fatty liver disease. ( Alisi, A; Bedogni, G; Donati, B; Nobili, V; Valenti, L, 2013) |
| "Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC)." | 2.66 | Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma. ( Goto, T; Hirotsu, Y; Kanda, T; Masuzaki, R; Moriyama, M; Omata, M, 2020) |
| "Metabolic syndrome is a cluster of metabolic abnormalities that identifies people at risk of diabetes and cardiovascular disease, whereas non-alcoholic fatty liver disease (NAFLD) is defined as a disorder with excess fat in the liver due to non-alcoholic causes." | 2.50 | Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome. ( Yki-Järvinen, H, 2014) |
| "Obesity is strongly associated with the prevalence of nonalcoholic fatty liver disease (NAFLD) in adult and pediatric populations." | 2.50 | Obesity-associated nonalcoholic fatty liver disease. ( Yilmaz, Y; Younossi, ZM, 2014) |
| "Nonalcoholic fatty liver disease (NAFLD) is a complex disease." | 2.50 | Host genetic variants in obesity-related nonalcoholic fatty liver disease. ( Birerdinc, A; Mehta, R; Younossi, ZM, 2014) |
| "Nonalcoholic fatty liver disease (NAFLD) is an obesity-related condition affecting over 50% of individuals in some populations and is expected to become the number one cause of liver disease worldwide by 2020." | 2.49 | Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent. ( Bielak, LF; Borecki, IB; Carr, JJ; Feitosa, MF; Harris, TB; Hernaez, R; Jhun, MA; Kahali, B; Kardia, SL; Langefeld, CD; Liu, J; Mosley, TH; Musani, SK; Norris, JM; Palmer, ND; Peyser, PA; Smith, AV; Speliotes, EK; Taylor, HA; Wagenknecht, LE; Yerges-Armstrong, LM, 2013) |
| "As such, NAFLD is best considered a complex disease trait resulting from environmental exposures acting on a susceptible polygenic background and comprising multiple independent modifiers." | 2.49 | The genetics of NAFLD. ( Anstee, QM; Day, CP, 2013) |
| "Nonalcoholic fatty liver disease is one of the most common hepatic disorders worldwide." | 2.49 | PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease. ( Krawczyk, M; Lammert, F; Portincasa, P, 2013) |
| "Nonalcoholic fatty liver disease (NAFLD) in most patients involves only simple hepatic steatosis; however, a minority develop progressive steatohepatitis." | 2.47 | Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease. ( Ballestri, S; Carulli, L; Daly, AK; Day, CP; Loria, P, 2011) |
| "Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3." | 2.47 | Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. ( Borecki, IB; Butler, JL; Carr, JJ; Clark, JM; Eiriksdottir, G; Feitosa, MF; Fox, CS; Garcia, ME; Gudnason, V; Harris, TB; Hernaez, R; Hirschhorn, JN; Hoffmann, U; Hwang, SJ; Kao, WH; Kim, LJ; Launer, LJ; Massaro, JM; Mitchell, BD; Nalls, MA; O'Donnell, CJ; Palmer, CD; Sahani, DV; Salomaa, V; Schadt, EE; Schwartz, SM; Shuldiner, AR; Siscovick, DS; Smith, AV; Speliotes, EK; Tomas, M; Voight, BF; Wu, J; Yerges-Armstrong, LM, 2011) |
| "Nonalcoholic steatohepatitis (NASH) was more frequently observed in GG than CC homozygous (odds ratio [OR] 3." | 2.47 | Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. ( Pirola, CJ; Sookoian, S, 2011) |
| "The pathogenesis of type 2 diabetes involves both insulin resistance and defects in insulin secretion." | 2.46 | Liver fat in the pathogenesis of insulin resistance and type 2 diabetes. ( Yki-Järvinen, H, 2010) |
| "Significant liver fibrosis regression occurs after hepatitis C virus (HCV) therapy." | 1.72 | Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants. ( Avihingsanon, A; Chuaypen, N; Hiranrat, P; Siripongsakun, S; Tangkijvanich, P; Tanpowpong, N, 2022) |
| "Liver steatosis is one of the side effects of chemotherapy." | 1.56 | Risk of chemotherapy-associated liver injury (CALI) in PNPLA3 p.148M allele carriers: Preliminary results of a transient elastography-based study. ( Arslanow, A; Casper, M; Krawczyk, M; Lammert, F; Weber, SN; Zimmermann, S, 2020) |
| "Fatty liver is tightly associated with insulin resistance and the development of type 2 diabetes." | 1.48 | Dissociation of Fatty Liver and Insulin Resistance in I148M PNPLA3 Carriers: Differences in Diacylglycerol (DAG) FA18:1 Lipid Species as a Possible Explanation. ( Franko, A; Häring, HU; Heni, M; Hoene, M; Jaghutriz, BA; Königsrainer, A; Kovarova, M; Lehr, S; Merkel, D; Papan, C; Peter, A, 2018) |
| "We recruited 515 patients with NAFLD (age 16-88 years, 280 female patients)." | 1.46 | Combined effects of the PNPLA3 rs738409, TM6SF2 rs58542926, and MBOAT7 rs641738 variants on NAFLD severity: a multicenter biopsy-based study. ( Bantel, H; Boettler, T; Demir, M; Geier, A; Kluwe, J; Krawczyk, M; Lammert, F; Pathil, A; Rau, M; Schattenberg, JM, 2017) |
| "Fatty liver is a potentially preventable cause of serious liver diseases." | 1.43 | Childhood predictors of adult fatty liver. The Cardiovascular Risk in Young Finns Study. ( Ahola-Olli, A; Hutri-Kähönen, N; Jokinen, E; Jula, A; Juonala, M; Kähönen, M; Laitinen, T; Lehtimäki, T; Loo, BM; Mikkilä, V; Oikonen, M; Parkkola, R; Pitkänen, N; Raitakari, OT; Suomela, E; Taittonen, L; Telama, R; Tossavainen, P; Viikari, JSA; Virtanen, J, 2016) |
| "Nonalcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease, manifests as an over-accumulation of hepatic fat." | 1.43 | LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL). ( Chen, G; Koenig, RJ; Liu, J; Nian, X; Sheng, L; Xu, B; Yu, D, 2016) |
| "Steatosis in hepatocellular carcinoma (HCC) has been recognized for decades and found most commonly in small, well-differentiated HCC." | 1.43 | Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse. ( Chan, AW; Chan, HL; Chan, SL; Chong, CC; Lai, PB; Tin, EK; To, KF; Tong, JH; Wang, L; Wong, GL; Wong, VW; Yu, S; Yu, YH, 2016) |
| "The effect of PNPLA3 on steatohepatitis was particularly pronounced among female patients without severe overweight." | 1.42 | The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients. ( Boonstra, A; Brouwer, WP; de Knegt, RJ; de Man, RA; Hansen, BE; Janssen, HL; Pas, SD; ten Kate, FJ; van der Meer, AJ, 2015) |
| "The etiologic ratio of HLAP in acute pancreatitis rose from 13% in 2009 to 25." | 1.42 | Different Clinical Presentations of Hyperlipidemic Acute Pancreatitis: A Retrospective Study. ( Cang, X; Chen, C; Cheng, G; Hu, G; Hu, Y; Huang, Y; Ni, J; Tang, M; Wan, R; Wang, S; Wang, X; Xing, M; Xiong, J; Yin, G; Yu, G; Zhao, Y, 2015) |
| "The prevalence of steatohepatitis increased from 16." | 1.42 | PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C. ( Abate, ML; Bugianesi, E; Cabibi, D; Cammà, C; Craxì, A; Di Marco, V; Eslam, M; George, J; Grimaudo, S; Macaluso, FS; McLeod, D; Petta, S; Pipitone, RM; Rosso, C; Smedile, A; Vanni, E, 2015) |
| "Advanced liver fibrosis was neither associated with PNPLA3 (p = 0." | 1.42 | The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection. ( Aichelburg, MC; Bota, S; Bucsics, T; Ferenci, P; Grabmeier-Pfistershammer, K; Mandorfer, M; Payer, BA; Peck-Radosavljevic, M; Reiberger, T; Scheiner, B; Schwabl, P; Stättermayer, A; Trauner, M, 2015) |
| "Obesity in pregnancy is associated with increased fetal growth and adiposity, which, in part, is determined by transplacental nutrient supply." | 1.42 | Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy. ( Díaz, P; Harris, J; Jansson, T; Powell, TL; Rosario, FJ, 2015) |
| "The prevalence of GG genotype in NAFLD subjects was 20." | 1.40 | PNPLA3 gene polymorphism accounts for fatty liver in community subjects without metabolic syndrome. ( Chan, AW; Chan, HL; Chan, HY; Chan, RS; Chim, AM; Choi, PC; Chu, WC; Shen, J; Wong, GL; Wong, VW; Woo, J; Yeung, DK, 2014) |
| "Obese NAFLD model was established in Sprague-Dawley rats by 8-week HFD feeding." | 1.40 | Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats. ( Guo, F; Li, S; Li, X; Li, Y; Liao, X; Meng, F; Meng, M; Sun, C; Sun, Z; Wang, Y, 2014) |
| "CT-defined fatty liver is common among men at risk for HIV infection and is associated with greater visceral adiposity, HOMA-IR, and PNPLA3 (rs738409)." | 1.40 | Risk factors for fatty liver in the Multicenter AIDS Cohort Study. ( Budoff, MJ; Kingsley, LA; Latanich, R; Palella, FJ; Post, WS; Price, JC; Seaberg, EC; Thio, CL; Witt, MD, 2014) |
| "Subjects made up of 144 biopsy-proven NAFLD patients and 198 controls were genotyped using TaqMan assays." | 1.39 | Susceptibility and gene interaction study of the angiotensin II type 1 receptor (AGTR1) gene polymorphisms with non-alcoholic fatty liver disease in a multi-ethnic population. ( Basu, RC; Cheah, PL; Mahadeva, S; Mohamed, R; Mohamed, Z; Rampal, S; Salim, A; Zain, SM, 2013) |
| "If NAFLD was suspected, liver biopsy was proposed." | 1.39 | A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population. ( Beckers, S; Caron, S; Francque, S; Hilden, H; Hubens, G; Michielsen, P; Ruppert, M; Staels, B; Taskinen, MR; Van Gaal, L; Van Hul, W; Van Marck, E; Verrijken, A; Zegers, D, 2013) |
| "The relationship of SNPs and NAFLD-related markers of liver function were assessed by correlation analysis." | 1.39 | [Polymorphism rs738409 in PNPLA3 is associated with inherited susceptibility to non-alcoholic fatty liver disease]. ( Dong, QJ; Jiang, XJ; Lin, ZH; Lü, WH; Xin, YN; Xu, J; Xuan, SY; Zhang, DD; Zhang, M, 2013) |
| "1." | 1.39 | PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma. ( Bertelli, C; Carnelutti, A; Colombo, M; Donati, B; Dongiovanni, P; Facchetti, F; Fargion, S; Fracanzani, AL; Iavarone, M; Motta, BM; Rametta, R; Sangiovanni, A; Soardo, G; Valenti, L, 2013) |
| "Hepatic cirrhosis was associated with a higher aspartate aminotransferase/platelet ratio index (APRI), no fatty change of the liver, higher BMI and higher AFP levels." | 1.39 | No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV. ( Jiang, X; Kanda, T; Miyamura, T; Nakamoto, S; Nakamura, M; Wu, S; Yokosuka, O, 2013) |
| "To evaluate if the presence of carotid atherosclerosis in patients with NAFLD, could be related to gene variants influencing hepatic fat accumulation and the severity of liver damage." | 1.39 | PNPLA3 GG genotype and carotid atherosclerosis in patients with non-alcoholic fatty liver disease. ( Barcellona, MR; Cabibi, D; Cammà, C; Craxì, A; Di Marco, V; Donati, B; Fargion, S; Fracanzani, A; Grimaudo, S; Licata, A; Licata, G; Marchesini, G; Parrinello, G; Petta, S; Pipitone, RM; Torres, D; Valenti, L, 2013) |
| "PNPLA3 NAFLD is characterised by an increase in liver fat but no insulin resistance or AT inflammation, while obese NAFLD has all three of these features." | 1.39 | Adipose tissue is inflamed in NAFLD due to obesity but not in NAFLD due to genetic variation in PNPLA3. ( Hakkarainen, A; Lallukka, S; Lundbom, N; Olkkonen, VM; Orho-Melander, M; Perttilä, J; Sevastianova, K; Yki-Järvinen, H, 2013) |
| "The etiology of NAFLD is multifactorial." | 1.39 | PNPLA3, a genetic marker of progressive liver disease, still hiding its metabolic function? ( Burnol, AF; Dubuquoy, C; Moldes, M, 2013) |
| "Non-alcoholic fatty liver disease (NAFLD) is characterized by insulin resistance." | 1.38 | Hepatic lipase activity is increased in non-alcoholic fatty liver disease beyond insulin resistance. ( Berg, G; Cacciagiú, L; Fassio, E; Gonzalez Ballerga, E; Lopez, G; Lucero, D; Miksztowicz, V; Schreier, L; Sordá, J; Zago, V, 2012) |
| "Insulin resistance is more common in carriers of the T allele of SNP rs12979860 than in CC homozygotes and may partly explain the poor outcome of peginterferon/ribavirin therapy in these patients." | 1.38 | Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C. ( Beinhardt, S; Datz, C; Ferenci, P; Hofer, H; Krebs, M; Rutter, K; Scherzer, TM; Stadlmayr, A; Stättermayer, AF; Steindl-Munda, P; Trauner, M; Wrba, F, 2012) |
| "Similarly, treatment of the fatty liver cell model with alpha-lipoic acid reduced intracellular lipid accumulation in HepG2 cells, increased AMPK phosphorylation, and induced ATGL expression." | 1.38 | Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells. ( Chen, WL; Kuo, YT; Lee, HM; Lin, TH, 2012) |
| "Mechanisms leading to non-alcoholic steatohepatitis (NASH) have remained unclear, and non-invasive diagnosis of NASH is challenging." | 1.38 | Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans. ( Grönlund, S; Gylling, H; Kainulainen, S; Käkelä, P; Kaminska, D; Kärjä, V; Kuulasmaa, T; Kuusisto, J; Laakso, M; Pääkkönen, M; Pihlajamäki, J; Punnonen, K; Simonen, M, 2012) |
| "Nonalcoholic fatty liver disease (NAFLD) is an escalating medical problem worldwide." | 1.38 | Genetic variant I148M in PNPLA3 is associated with the ultrasonography-determined steatosis degree in a Chinese population. ( Ku, HC; Li, Y; Tian, Z; Xing, C, 2012) |
| "Non-alcoholic fatty liver disease (NAFLD) is a complex disease trait where genetic variations and environment interact to determine disease progression." | 1.38 | The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies. ( Al-Serri, A; Anstee, QM; Daly, AK; Day, CP; Dongiovanni, P; Fargion, S; Fracanzani, A; Leathart, JB; Nobili, V; Patch, J; Valenti, L, 2012) |
| "A total of 144 biopsy-proven NAFLD patients and 198 controls were genotyped for PNPLA3 gene polymorphism (rs738409 C>G)." | 1.38 | A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease. ( Basu, RC; Cheah, PL; Mahadeva, S; Mohamed, R; Mohamed, Z; Rampal, S; Zain, SM, 2012) |
| "One hundred sixty consecutive NAFLD patients were assessed by liver biopsy (Kleiner score); anthropometric, and biochemical and metabolic features were included." | 1.38 | IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease. ( Cabibi, D; Cammà, C; Craxì, A; Di Marco, V; Grimaudo, S; Licata, G; Petta, S; Pipitone, RM, 2012) |
| "Nonalcoholic fatty liver disease (NAFLD) is characterized by triglyceride (TG) accumulation and endoplasmic reticulum (ER) stress." | 1.38 | Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice. ( Claudel, T; Fuchs, CD; Gumhold, J; Haemmerle, G; Halilbasic, E; Koefeler, H; Kumari, P; Pollheimer, MJ; Scharnagl, H; Silbert, D; Stojakovic, T; Trauner, M, 2012) |
| "Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent condition, particularly among Hispanic Americans." | 1.37 | Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study. ( Bowden, DW; Chen, YD; Haffner, S; Langefeld, CD; Norris, JM; Palmer, ND; Rotter, JI; Scherzinger, A; Wagenknecht, LE; Ziegler, J, 2011) |
| "NAFLD was present in 19." | 1.37 | A common variant in the PNPLA3 gene is a risk factor for non-alcoholic fatty liver disease in obese Taiwanese children. ( Chang, MH; Chang, PF; Hu, FC; Lin, YC; Ni, YH; Yang, WS, 2011) |
| "Nonalcoholic fatty liver disease (NAFLD) has recently been considered a hepatic component of insulin resistance and a risk factor in the emergence of type 2 diabetes." | 1.37 | The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population. ( Chen, SC; Chuang, WL; Dai, CY; Huang, JF; Li, SS; Lin, HY; Lin, ZY; Shin, SJ; Wang, CW; Yu, ML, 2011) |
| "Advanced liver fibrosis (stage F2 or above) was observed in 10." | 1.37 | PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes. ( Bouillet, B; Brindisi, MC; Buffier, P; Cercueil, JP; Duvillard, L; Gambert, P; Guiu, B; Hillon, P; Jooste, V; Masson, D; Petit, JM; Robin, I; Verges, B, 2011) |
| "Non-alcoholic fatty liver disease (NAFLD) is commonly diagnosed in patients with obesity and type 2 diabetes mellitus (T2DM), and has been associated with the single nucleotide polymorphism (SNP) rs738409 in the PNPLA3 gene." | 1.37 | Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus. ( Bowden, DW; Carr, JJ; Cox, AJ; Freedman, BI; Hightower, RC; Smith, SC; Wagenknecht, LE; Wing, MR; Xu, J, 2011) |
| "APOC3 SNPs were not associated with NAFLD in Italian subjects, although a borderline significance for the transmission of the -455T allele was observed in the family study." | 1.37 | The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver. ( Al-Serri, A; Alterio, A; Daly, AK; Day, CP; Dongiovanni, P; Fargion, S; Fracanzani, AL; Leathart, JB; Nobili, V; Rametta, R; Roviaro, G; Valenti, L; Zappa, MA, 2011) |
| "All patients with NAFLD underwent liver biopsy." | 1.36 | Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease. ( Chayama, K; Hotta, K; Hyogo, H; Mizusawa, S; Nakajima, A; Nakao, K; Ochi, H; Sekine, A; Ueno, T; Yoneda, M, 2010) |
| "Liver steatosis was more prevalent in carriers of two 148M alleles." | 1.36 | The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life. ( Baroni, MG; Cambuli, VM; Congiu, T; Cossu, E; Huang-Doran, I; Incani, M; Loche, S; Matta, V; Pilia, S; Romeo, S; Sentinelli, F, 2010) |
| "This study confirms that in people with type 2 diabetes, LFC is related to rs738409 polymorphism." | 1.36 | Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes. ( Bouillet, B; Brindisi, MC; Buffier, P; Cercueil, JP; Duvillard, L; Guiu, B; Hillon, P; Jooste, V; Loffroy, R; Masson, D; Petit, JM; Robin, I; Terriat, B; Verges, B, 2010) |
| "In 26 patients with morbid obesity who underwent bariatric surgery, we analyzed different kinds of lipids and hepatic lipase (HL) from both plasma and liver biopsies performed 12-18 months after surgery." | 1.35 | Increased expression and activity of hepatic lipase in the liver of morbidly obese adult patients in relation to lipid content. ( Allende, H; Baena-Fustegueras, JA; Catalán, R; Fort, JM; Galard, R; Lecube, A; Pardina, E; Peinado-Onsurbe, J; Vargas, V, 2009) |
| "Insulin sensitivity was estimated during an oral glucose tolerance test and the euglycemic-hyperinsulinemic clamp (n = 222)." | 1.35 | Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. ( Fritsche, A; Häring, HU; Kantartzis, K; Königsrainer, A; Königsrainer, I; Machann, J; Machicao, F; Peter, A; Schick, F; Stefan, N; Wagner, S, 2009) |
| "Nonalcoholic steatohepatitis (NASH) may cause progressive hepatic fibrosis, cirrhosis, and hepatocellular carcinoma." | 1.34 | Orlistat reverse fatty infiltration and improves hepatic fibrosis in obese patients with nonalcoholic steatohepatitis (NASH). ( Assy, N; Grosovski, M; Hussein, O; Schlesinger, S; Szvalb, S, 2007) |
| "Nonalcoholic steatohepatitis (NASH) is characterized by steatosis, inflammation, and oxidative stress." | 1.34 | CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis. ( Friedman, JE; Janssen, RC; Jiang, H; Maclean, KN; Qadri, I; Rahman, SM; Schroeder-Gloeckler, JM, 2007) |
| "Pancreatitis is a serious side effect." | 1.30 | Dideoxyinosine-induced pancreatitis in human immunodeficiency virus-infected children. ( Berdon, WE; Haller, JO; Levin, TL; Tang, HB, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (6.49) | 18.7374 |
| 1990's | 3 (1.15) | 18.2507 |
| 2000's | 26 (9.92) | 29.6817 |
| 2010's | 200 (76.34) | 24.3611 |
| 2020's | 16 (6.11) | 2.80 |
| Authors | Studies |
|---|---|
| Gavril, OI | 1 |
| Arhire, LI | 1 |
| Gavrilescu, O | 1 |
| Dranga, M | 1 |
| Barboi, O | 1 |
| Gavril, RS | 1 |
| Popescu, R | 1 |
| Cijevschi Prelipcean, C | 1 |
| Trifan, AV | 1 |
| Mihai, C | 1 |
| Patsenker, E | 1 |
| Thangapandi, VR | 1 |
| Knittelfelder, O | 2 |
| Palladini, A | 1 |
| Hefti, M | 1 |
| Beil-Wagner, J | 1 |
| Rogler, G | 1 |
| Buch, T | 1 |
| Shevchenko, A | 1 |
| Hampe, J | 2 |
| Stickel, F | 2 |
| Chuaypen, N | 1 |
| Siripongsakun, S | 1 |
| Hiranrat, P | 1 |
| Tanpowpong, N | 1 |
| Avihingsanon, A | 1 |
| Tangkijvanich, P | 1 |
| Ashour, H | 1 |
| Rashed, LA | 1 |
| Hassanein, RTM | 1 |
| Aboulhoda, BE | 1 |
| Ebrahim, HA | 1 |
| Elsayed, MH | 1 |
| Elkordy, MA | 1 |
| Abdelwahed, OM | 1 |
| Xu, J | 3 |
| Liu, Z | 1 |
| Zhang, J | 1 |
| Chen, S | 1 |
| Wang, W | 1 |
| Zhao, X | 1 |
| Zhen, M | 1 |
| Huang, X | 1 |
| Thomes, PG | 1 |
| Strupp, MS | 1 |
| Donohue, TM | 1 |
| Kubik, JL | 1 |
| Sweeney, S | 1 |
| Mahmud, R | 1 |
| Schott, MB | 1 |
| Schulze, RJ | 1 |
| McNiven, MA | 1 |
| Casey, CA | 1 |
| Korbelius, M | 1 |
| Vujic, N | 1 |
| Sachdev, V | 1 |
| Obrowsky, S | 1 |
| Rainer, S | 1 |
| Gottschalk, B | 1 |
| Graier, WF | 1 |
| Kratky, D | 1 |
| Kuttner, CS | 1 |
| Mancina, R | 1 |
| Wagenpfeil, G | 1 |
| Lammert, F | 5 |
| Stokes, CS | 1 |
| Crisan, D | 1 |
| Grigorescu, M | 1 |
| Crisan, N | 1 |
| Craciun, R | 1 |
| Lupsor, M | 1 |
| Radu, C | 1 |
| Grigorescu, MD | 1 |
| Suciu, A | 1 |
| Epure, F | 1 |
| Avram, L | 1 |
| Leach, N | 1 |
| Casper, M | 1 |
| Zimmermann, S | 1 |
| Weber, SN | 1 |
| Arslanow, A | 1 |
| Krawczyk, M | 3 |
| Fukaishi, T | 1 |
| Minami, I | 1 |
| Masuda, S | 1 |
| Miyachi, Y | 1 |
| Tsujimoto, K | 1 |
| Izumiyama, H | 1 |
| Hashimoto, K | 1 |
| Yoshida, M | 1 |
| Takahashi, S | 1 |
| Kashimada, K | 1 |
| Morio, T | 1 |
| Kosaki, K | 1 |
| Maezawa, Y | 1 |
| Yokote, K | 1 |
| Yoshimoto, T | 1 |
| Yamada, T | 1 |
| Youssef, SS | 1 |
| Abbas, EAER | 1 |
| Youness, RA | 1 |
| Elemeery, MN | 1 |
| Nasr, AS | 1 |
| Seif, S | 1 |
| Kanda, T | 2 |
| Goto, T | 1 |
| Hirotsu, Y | 1 |
| Masuzaki, R | 1 |
| Moriyama, M | 1 |
| Omata, M | 1 |
| Wang, X | 2 |
| Guo, M | 1 |
| Wang, Q | 2 |
| Zuo, S | 1 |
| Zhang, X | 1 |
| Tong, H | 1 |
| Chen, J | 1 |
| Wang, H | 2 |
| Chen, X | 1 |
| Guo, J | 1 |
| Su, X | 1 |
| Liang, H | 1 |
| Zhou, H | 1 |
| Li, JZ | 2 |
| Magri, MC | 2 |
| Manchiero, C | 2 |
| Prata, TVG | 1 |
| Nunes, AKDS | 2 |
| Oliveira Junior, JS | 1 |
| Dantas, BP | 2 |
| Tengan, FM | 2 |
| Song, YF | 1 |
| Hogstrand, C | 1 |
| Ling, SC | 1 |
| Chen, GH | 1 |
| Luo, Z | 1 |
| Schwerbel, K | 1 |
| Kamitz, A | 1 |
| Krahmer, N | 1 |
| Hallahan, N | 1 |
| Jähnert, M | 1 |
| Gottmann, P | 1 |
| Lebek, S | 1 |
| Schallschmidt, T | 1 |
| Arends, D | 1 |
| Schumacher, F | 1 |
| Kleuser, B | 1 |
| Haltenhof, T | 1 |
| Heyd, F | 1 |
| Gancheva, S | 1 |
| Broman, KW | 1 |
| Roden, M | 1 |
| Joost, HG | 1 |
| Chadt, A | 1 |
| Al-Hasani, H | 1 |
| Vogel, H | 1 |
| Jonas, W | 1 |
| Schürmann, A | 1 |
| Wei, W | 1 |
| Li, Y | 6 |
| Li, D | 1 |
| Cohen, CC | 1 |
| Perng, W | 1 |
| Sauder, KA | 1 |
| Ringham, BM | 1 |
| Bellatorre, A | 1 |
| Scherzinger, A | 2 |
| Stanislawski, MA | 1 |
| Lange, LA | 1 |
| Shankar, K | 1 |
| Dabelea, D | 1 |
| Schweiger, M | 3 |
| Romauch, M | 1 |
| Schreiber, R | 1 |
| Grabner, GF | 1 |
| Hütter, S | 1 |
| Kotzbeck, P | 1 |
| Benedikt, P | 1 |
| Eichmann, TO | 2 |
| Yamada, S | 1 |
| Diwoky, C | 1 |
| Doler, C | 1 |
| Mayer, N | 1 |
| De Cecco, W | 1 |
| Breinbauer, R | 1 |
| Zimmermann, R | 3 |
| Zechner, R | 5 |
| Valenti, L | 19 |
| Dongiovanni, P | 14 |
| Dold, L | 1 |
| Luda, C | 1 |
| Schwarze-Zander, C | 1 |
| Boesecke, C | 1 |
| Hansel, C | 1 |
| Nischalke, HD | 1 |
| Lutz, P | 1 |
| Mohr, R | 1 |
| Wasmuth, JC | 1 |
| Strassburg, CP | 1 |
| Trebicka, J | 1 |
| Rockstroh, JK | 1 |
| Spengler, U | 1 |
| Wallstab, C | 1 |
| Eleftheriadou, D | 1 |
| Schulz, T | 1 |
| Damm, G | 1 |
| Seehofer, D | 1 |
| Borlak, J | 1 |
| Holzhütter, HG | 1 |
| Berndt, N | 1 |
| Khaleel, EF | 1 |
| Abdel-Aleem, GA | 1 |
| Mostafa, DG | 1 |
| Huang, CM | 1 |
| Chang, KC | 1 |
| Hung, CH | 1 |
| Chiu, KW | 1 |
| Lu, SN | 1 |
| Wang, JH | 1 |
| Chen, CH | 1 |
| Kee, KM | 1 |
| Kuo, YH | 1 |
| Tsai, MC | 1 |
| Tseng, PL | 1 |
| Lin, MT | 1 |
| Wu, CK | 1 |
| Hu, TH | 1 |
| Cho, CL | 1 |
| Yen, YH | 1 |
| Pierce, AA | 1 |
| Duwaerts, CC | 1 |
| Siao, K | 1 |
| Mattis, AN | 1 |
| Goodsell, A | 1 |
| Baron, JL | 1 |
| Maher, JJ | 1 |
| Ghalamkari, S | 1 |
| Sharafi, H | 1 |
| Alavian, SM | 1 |
| Cedó, L | 1 |
| Santos, D | 1 |
| Roglans, N | 1 |
| Julve, J | 1 |
| Pallarès, V | 1 |
| Rivas-Urbina, A | 1 |
| Llorente-Cortes, V | 1 |
| Laguna, JC | 1 |
| Blanco-Vaca, F | 1 |
| Escolà-Gil, JC | 1 |
| Mazza, CC | 1 |
| Barone, AA | 1 |
| Trunečka, P | 1 |
| Míková, I | 1 |
| Dlouhá, D | 1 |
| Hubáček, JA | 1 |
| Honsová, E | 1 |
| Kolesár, L | 1 |
| Lánská, V | 1 |
| Fraňková, S | 1 |
| Šperl, J | 1 |
| Jirsa, M | 1 |
| Poledne, R | 1 |
| Mandorfer, M | 2 |
| Scheiner, B | 2 |
| Stättermayer, AF | 2 |
| Schwabl, P | 2 |
| Paternostro, R | 1 |
| Bauer, D | 1 |
| Schaefer, B | 1 |
| Zoller, H | 2 |
| Peck-Radosavljevic, M | 2 |
| Trauner, M | 6 |
| Reiberger, T | 2 |
| Ferenci, P | 3 |
| Ferlitsch, A | 1 |
| Tortora, R | 1 |
| Rispo, A | 1 |
| Alisi, A | 4 |
| Imperatore, N | 1 |
| Crudele, A | 2 |
| Ferretti, F | 1 |
| Nobili, V | 8 |
| Miele, L | 1 |
| Gerbino, N | 1 |
| Caporaso, N | 1 |
| Morisco, F | 1 |
| Franko, A | 1 |
| Merkel, D | 1 |
| Kovarova, M | 2 |
| Hoene, M | 1 |
| Jaghutriz, BA | 1 |
| Heni, M | 1 |
| Königsrainer, A | 3 |
| Papan, C | 1 |
| Lehr, S | 1 |
| Häring, HU | 5 |
| Peter, A | 3 |
| Zampino, R | 3 |
| Macera, M | 3 |
| Cirillo, G | 5 |
| Pafundi, PC | 1 |
| Rinaldi, L | 1 |
| Coppola, N | 4 |
| Pisaturo, M | 2 |
| Adinolfi, LE | 3 |
| Miraglia Del Giudice, E | 3 |
| Ingrosso, D | 1 |
| Capasso, R | 1 |
| Hayashi, R | 1 |
| Okuno, Y | 1 |
| Mukai, K | 1 |
| Kitamura, T | 1 |
| Hayakawa, T | 1 |
| Onodera, T | 1 |
| Murata, M | 1 |
| Fukuhara, A | 1 |
| Imamura, R | 1 |
| Miyagawa, Y | 1 |
| Nonomura, N | 1 |
| Otsuki, M | 1 |
| Shimomura, I | 1 |
| Bedogni, G | 2 |
| De Matteis, G | 1 |
| Fabrizi, M | 1 |
| Pizzolante, F | 1 |
| Signore, F | 1 |
| Dallapiccola, B | 1 |
| Manco, M | 1 |
| Li, J | 2 |
| Gong, L | 1 |
| Liu, S | 1 |
| Zhang, Y | 3 |
| Zhang, C | 2 |
| Tian, M | 1 |
| Lu, H | 1 |
| Bu, P | 1 |
| Yang, J | 1 |
| Ouyang, C | 1 |
| Jiang, X | 2 |
| Wu, J | 2 |
| Min, Q | 1 |
| Zhang, W | 1 |
| Hernaez, R | 3 |
| McLean, J | 1 |
| Lazo, M | 1 |
| Brancati, FL | 1 |
| Hirschhorn, JN | 3 |
| Borecki, IB | 4 |
| Harris, TB | 3 |
| Nguyen, T | 1 |
| Kamel, IR | 1 |
| Bonekamp, S | 1 |
| Eberhardt, MS | 1 |
| Clark, JM | 2 |
| Kao, WH | 2 |
| Speliotes, EK | 4 |
| Guichelaar, MM | 1 |
| Gawrieh, S | 1 |
| Olivier, M | 1 |
| Viker, K | 1 |
| Krishnan, A | 1 |
| Sanderson, S | 1 |
| Malinchoc, M | 1 |
| Watt, KD | 1 |
| Swain, JM | 1 |
| Sarr, M | 1 |
| Charlton, MR | 1 |
| Zain, SM | 2 |
| Mohamed, Z | 2 |
| Mahadeva, S | 2 |
| Rampal, S | 2 |
| Basu, RC | 2 |
| Cheah, PL | 2 |
| Salim, A | 1 |
| Mohamed, R | 2 |
| Verrijken, A | 1 |
| Beckers, S | 1 |
| Francque, S | 1 |
| Hilden, H | 1 |
| Caron, S | 1 |
| Zegers, D | 1 |
| Ruppert, M | 1 |
| Hubens, G | 1 |
| Van Marck, E | 1 |
| Michielsen, P | 1 |
| Staels, B | 1 |
| Taskinen, MR | 2 |
| Van Hul, W | 1 |
| Van Gaal, L | 1 |
| Kitamoto, T | 1 |
| Kitamoto, A | 1 |
| Yoneda, M | 2 |
| Hyogo, H | 2 |
| Ochi, H | 2 |
| Nakamura, T | 1 |
| Teranishi, H | 1 |
| Mizusawa, S | 2 |
| Ueno, T | 2 |
| Chayama, K | 2 |
| Nakajima, A | 2 |
| Nakao, K | 2 |
| Sekine, A | 2 |
| Hotta, K | 2 |
| Palmer, ND | 2 |
| Musani, SK | 1 |
| Yerges-Armstrong, LM | 2 |
| Feitosa, MF | 2 |
| Bielak, LF | 1 |
| Kahali, B | 1 |
| Carr, JJ | 4 |
| Jhun, MA | 1 |
| Kardia, SL | 1 |
| Langefeld, CD | 2 |
| Mosley, TH | 1 |
| Norris, JM | 2 |
| Smith, AV | 2 |
| Taylor, HA | 1 |
| Wagenknecht, LE | 3 |
| Liu, J | 2 |
| Peyser, PA | 1 |
| Viganò, M | 1 |
| Lampertico, P | 1 |
| Facchetti, F | 2 |
| Motta, BM | 3 |
| D'Ambrosio, R | 2 |
| Romagnoli, S | 1 |
| Donati, B | 5 |
| Fargion, S | 14 |
| Colombo, M | 5 |
| Browning, JD | 2 |
| Bhatt, SP | 1 |
| Nigam, P | 1 |
| Misra, A | 1 |
| Guleria, R | 1 |
| Pandey, RM | 1 |
| Pasha, MA | 1 |
| Doganay, L | 1 |
| Ozdil, K | 1 |
| Sokmen, M | 1 |
| Dunn, W | 2 |
| Weinman, S | 1 |
| Walker, RW | 2 |
| Sinatra, F | 1 |
| Hartiala, J | 1 |
| Weigensberg, M | 1 |
| Spruijt-Metz, D | 3 |
| Alderete, TL | 1 |
| Goran, MI | 5 |
| Allayee, H | 4 |
| Boemio, A | 2 |
| Marrone, A | 2 |
| Sagnelli, E | 3 |
| Perrone, L | 3 |
| Santoro, N | 5 |
| Caprio, S | 4 |
| Giannini, C | 2 |
| Kim, G | 3 |
| Kursawe, R | 3 |
| Pierpont, B | 4 |
| Shaw, MM | 4 |
| Feldstein, AE | 1 |
| Marzuillo, P | 3 |
| Grandone, A | 4 |
| del Giudice, EM | 4 |
| Finkenstedt, A | 1 |
| Auer, C | 1 |
| Glodny, B | 1 |
| Posch, U | 1 |
| Steitzer, H | 1 |
| Lanzer, G | 1 |
| Pratschke, J | 1 |
| Biebl, M | 1 |
| Steurer, M | 1 |
| Graziadei, I | 1 |
| Vogel, W | 1 |
| Petäjä, EM | 1 |
| Sevastianova, K | 5 |
| Hakkarainen, A | 6 |
| Orho-Melander, M | 5 |
| Lundbom, N | 6 |
| Yki-Järvinen, H | 9 |
| Jha, P | 2 |
| Claudel, T | 3 |
| Baghdasaryan, A | 1 |
| Mueller, M | 2 |
| Halilbasic, E | 2 |
| Das, SK | 1 |
| Lass, A | 2 |
| Hoefler, G | 3 |
| Miyamoto, T | 1 |
| Ono, M | 1 |
| Saibara, T | 2 |
| Hyysalo, J | 2 |
| Gopalacharyulu, P | 1 |
| Bian, H | 1 |
| Hyötyläinen, T | 1 |
| Leivonen, M | 1 |
| Jaser, N | 1 |
| Juuti, A | 1 |
| Honka, MJ | 1 |
| Nuutila, P | 1 |
| Olkkonen, VM | 3 |
| Oresic, M | 1 |
| Anstee, QM | 2 |
| Day, CP | 5 |
| Petta, S | 5 |
| Marchesini, G | 2 |
| Di Marco, V | 4 |
| Licata, A | 1 |
| Cammà, C | 4 |
| Barcellona, MR | 1 |
| Cabibi, D | 4 |
| Fracanzani, A | 2 |
| Grimaudo, S | 4 |
| Parrinello, G | 1 |
| Pipitone, RM | 4 |
| Torres, D | 1 |
| Licata, G | 2 |
| Craxì, A | 5 |
| Xin, YN | 1 |
| Lü, WH | 1 |
| Lin, ZH | 1 |
| Zhang, DD | 1 |
| Zhang, M | 1 |
| Dong, QJ | 1 |
| Jiang, XJ | 1 |
| Xuan, SY | 1 |
| Soardo, G | 1 |
| Iavarone, M | 1 |
| Sangiovanni, A | 1 |
| Carnelutti, A | 1 |
| Rametta, R | 8 |
| Bertelli, C | 1 |
| Fracanzani, AL | 7 |
| Portincasa, P | 1 |
| Fares, R | 1 |
| Lombardi, R | 1 |
| Mancina, RM | 2 |
| Romeo, S | 8 |
| Yilmaz, Y | 1 |
| Younossi, ZM | 2 |
| Mehta, R | 1 |
| Birerdinc, A | 1 |
| Karahashi, M | 1 |
| Hoshina, M | 1 |
| Yamazaki, T | 1 |
| Sakamoto, T | 1 |
| Mitsumoto, A | 1 |
| Kawashima, Y | 1 |
| Kudo, N | 1 |
| Nakamura, M | 1 |
| Nakamoto, S | 1 |
| Miyamura, T | 1 |
| Wu, S | 1 |
| Yokosuka, O | 1 |
| Mashek, DG | 3 |
| Greenberg, AS | 2 |
| Shen, J | 3 |
| Wong, GL | 3 |
| Chan, HL | 3 |
| Chan, HY | 2 |
| Yeung, DK | 2 |
| Chan, RS | 2 |
| Chim, AM | 1 |
| Chan, AW | 2 |
| Choi, PC | 1 |
| Woo, J | 2 |
| Chu, WC | 3 |
| Wong, VW | 4 |
| Lin, YC | 3 |
| Chang, PF | 3 |
| Chang, MH | 3 |
| Ni, YH | 3 |
| Li, S | 1 |
| Liao, X | 1 |
| Meng, F | 1 |
| Wang, Y | 1 |
| Sun, Z | 1 |
| Guo, F | 2 |
| Li, X | 1 |
| Meng, M | 1 |
| Sun, C | 2 |
| Grasselli, E | 2 |
| Voci, A | 2 |
| Canesi, L | 2 |
| Salis, A | 1 |
| Damonte, G | 1 |
| Compalati, AD | 1 |
| Goglia, F | 2 |
| Gallo, G | 2 |
| Vergani, L | 2 |
| Moritou, Y | 1 |
| Ikeda, F | 1 |
| Iwasaki, Y | 1 |
| Baba, N | 1 |
| Takaguchi, K | 1 |
| Senoh, T | 1 |
| Nagano, T | 1 |
| Takeuchi, Y | 1 |
| Yasunaka, T | 1 |
| Ohnishi, H | 1 |
| Miyake, Y | 1 |
| Takaki, A | 1 |
| Nouso, K | 1 |
| Yamamoto, K | 1 |
| Knopf, A | 1 |
| Koefeler, H | 2 |
| Lackner, C | 2 |
| Stinton, L | 1 |
| Loomba, R | 1 |
| Price, JC | 1 |
| Seaberg, EC | 1 |
| Latanich, R | 1 |
| Budoff, MJ | 1 |
| Kingsley, LA | 1 |
| Palella, FJ | 1 |
| Witt, MD | 1 |
| Post, WS | 1 |
| Thio, CL | 1 |
| Larrieta-Carrasco, E | 1 |
| Acuña-Alonzo, V | 1 |
| Velázquez-Cruz, R | 1 |
| Barquera-Lozano, R | 1 |
| León-Mimila, P | 1 |
| Villamil-Ramírez, H | 1 |
| Menjivar, M | 1 |
| Romero-Hidalgo, S | 1 |
| Méndez-Sánchez, N | 1 |
| Cárdenas, V | 1 |
| Bañuelos-Moreno, M | 1 |
| Flores, YN | 1 |
| Quiterio, M | 1 |
| Salmerón, J | 1 |
| Sánchez-Muñoz, F | 1 |
| Villarreal-Molina, T | 2 |
| Aguilar-Salinas, CA | 1 |
| Canizales-Quinteros, S | 1 |
| Alfaradhi, MZ | 1 |
| Fernandez-Twinn, DS | 1 |
| Martin-Gronert, MS | 1 |
| Musial, B | 1 |
| Fowden, A | 1 |
| Ozanne, SE | 1 |
| Ruscica, M | 2 |
| Macchi, C | 1 |
| Steffani, L | 2 |
| Magni, P | 2 |
| Smagris, E | 2 |
| BasuRay, S | 2 |
| Huang, Y | 3 |
| Lai, KM | 1 |
| Gromada, J | 2 |
| Cohen, JC | 7 |
| Hobbs, HH | 7 |
| Ray, K | 1 |
| Cheung, BH | 1 |
| Li, LS | 1 |
| Sea, MM | 1 |
| Sookoian, S | 4 |
| Castaño, GO | 1 |
| Pirola, CJ | 4 |
| De Nicola, S | 2 |
| Aghemo, A | 3 |
| Cheroni, C | 1 |
| Pedrazzini, M | 1 |
| Marabita, F | 1 |
| Donnici, L | 1 |
| Maggioni, M | 3 |
| De Francesco, R | 1 |
| Boursier, J | 1 |
| Diehl, AM | 2 |
| Conte, M | 1 |
| Capuano, F | 1 |
| Di Sessa, A | 1 |
| Umano, GR | 1 |
| Romano, R | 1 |
| Brouwer, WP | 1 |
| van der Meer, AJ | 1 |
| Boonstra, A | 1 |
| Pas, SD | 1 |
| de Knegt, RJ | 1 |
| de Man, RA | 1 |
| Hansen, BE | 1 |
| ten Kate, FJ | 1 |
| Janssen, HL | 1 |
| Dong, GF | 1 |
| Liu, WZ | 1 |
| Wu, LZ | 1 |
| Yu, DH | 1 |
| Huang, F | 1 |
| Li, PC | 1 |
| Yang, YO | 1 |
| Shirakawa, T | 1 |
| Nakajima, K | 1 |
| Yatsuzuka, S | 1 |
| Shimomura, Y | 1 |
| Kobayashi, J | 1 |
| Machida, T | 1 |
| Sumino, H | 1 |
| Murakami, M | 1 |
| Yasui, K | 2 |
| Kawaguchi, T | 2 |
| Shima, T | 2 |
| Mitsuyoshi, H | 1 |
| Seki, K | 1 |
| Sendo, R | 1 |
| Mizuno, M | 1 |
| Itoh, Y | 1 |
| Matsuda, F | 2 |
| Okanoue, T | 2 |
| Posadas-Sánchez, R | 2 |
| Ocampo-Arcos, WA | 2 |
| López-Uribe, ÁR | 2 |
| Posadas-Romero, C | 2 |
| León, EÁ | 1 |
| Pérez-Hernández, N | 2 |
| Rodríguez-Pérez, JM | 2 |
| Cardoso-Saldaña, G | 2 |
| Medina-Urrutia, A | 1 |
| Vargas-Alarcón, G | 2 |
| Matikainen, N | 1 |
| Maglio, C | 3 |
| Söderlund, S | 1 |
| Mozzi, E | 3 |
| Borén, J | 1 |
| Vanni, E | 2 |
| Bugianesi, E | 3 |
| Rosso, C | 1 |
| Eslam, M | 1 |
| Macaluso, FS | 2 |
| McLeod, D | 1 |
| Abate, ML | 1 |
| Smedile, A | 1 |
| George, J | 1 |
| Wu, P | 1 |
| Shu, Y | 1 |
| Luo, H | 1 |
| Zhang, G | 1 |
| Tan, S | 1 |
| Kaushik, S | 1 |
| Cuervo, AM | 1 |
| Stanzione, M | 1 |
| Capoluongo, N | 1 |
| Wu, JW | 2 |
| Yang, H | 2 |
| Mitchell, GA | 3 |
| Huang, CF | 1 |
| Chen, JJ | 1 |
| Yeh, ML | 1 |
| Huang, CI | 1 |
| Hsieh, MY | 1 |
| Yang, HL | 1 |
| Dai, CY | 2 |
| Huang, JF | 2 |
| Lin, ZY | 2 |
| Chen, SC | 2 |
| Chuang, WL | 2 |
| Chen, YL | 1 |
| Yu, ML | 2 |
| Argo, CK | 1 |
| Ikura, Y | 1 |
| Caldwell, SH | 1 |
| Burton, BK | 1 |
| Deegan, PB | 1 |
| Enns, GM | 1 |
| Guardamagna, O | 1 |
| Horslen, S | 1 |
| Hovingh, GK | 1 |
| Lobritto, SJ | 1 |
| Malinova, V | 1 |
| McLin, VA | 1 |
| Raiman, J | 1 |
| Di Rocco, M | 1 |
| Santra, S | 1 |
| Sharma, R | 1 |
| Sykut-Cegielska, J | 1 |
| Whitley, CB | 1 |
| Eckert, S | 1 |
| Valayannopoulos, V | 1 |
| Quinn, AG | 1 |
| Maida, M | 1 |
| Sferrazza, S | 1 |
| Yin, G | 1 |
| Cang, X | 1 |
| Yu, G | 1 |
| Hu, G | 1 |
| Ni, J | 1 |
| Xiong, J | 1 |
| Hu, Y | 1 |
| Xing, M | 1 |
| Chen, C | 1 |
| Tang, M | 1 |
| Zhao, Y | 1 |
| Cheng, G | 1 |
| Wan, R | 1 |
| Wang, S | 1 |
| Tamaki, N | 1 |
| Kurosaki, M | 1 |
| Higuchi, M | 1 |
| Takada, H | 1 |
| Nakakuki, N | 1 |
| Yasui, Y | 1 |
| Suzuki, S | 1 |
| Tsuchiya, K | 1 |
| Nakanishi, H | 1 |
| Itakura, J | 1 |
| Takahashi, Y | 1 |
| Ogawa, S | 1 |
| Tanaka, Y | 1 |
| Asahina, Y | 1 |
| Izumi, N | 1 |
| Fan, JH | 1 |
| Xiang, MQ | 1 |
| Li, QL | 1 |
| Shi, HT | 1 |
| Guo, JJ | 1 |
| Königsrainer, I | 2 |
| Machicao, F | 2 |
| Schleicher, E | 1 |
| Díaz, P | 1 |
| Harris, J | 1 |
| Rosario, FJ | 1 |
| Powell, TL | 1 |
| Jansson, T | 1 |
| Payer, BA | 1 |
| Bucsics, T | 1 |
| Bota, S | 1 |
| Aichelburg, MC | 1 |
| Grabmeier-Pfistershammer, K | 1 |
| Stättermayer, A | 1 |
| Sagnelli, C | 1 |
| Merli, M | 1 |
| Uberti-Foppa, C | 1 |
| Hasson, H | 1 |
| Salpietro, S | 1 |
| Minichini, C | 1 |
| Lazzarin, A | 1 |
| Marmugi, A | 1 |
| Lukowicz, C | 1 |
| Lasserre, F | 1 |
| Montagner, A | 1 |
| Polizzi, A | 1 |
| Ducheix, S | 1 |
| Goron, A | 1 |
| Gamet-Payrastre, L | 1 |
| Gerbal-Chaloin, S | 1 |
| Pascussi, JM | 1 |
| Moldes, M | 3 |
| Pineau, T | 1 |
| Guillou, H | 1 |
| Mselli-Lakhal, L | 1 |
| Suomela, E | 1 |
| Oikonen, M | 1 |
| Pitkänen, N | 1 |
| Ahola-Olli, A | 1 |
| Virtanen, J | 1 |
| Parkkola, R | 1 |
| Jokinen, E | 1 |
| Laitinen, T | 1 |
| Hutri-Kähönen, N | 1 |
| Kähönen, M | 1 |
| Lehtimäki, T | 1 |
| Taittonen, L | 1 |
| Tossavainen, P | 1 |
| Jula, A | 1 |
| Loo, BM | 1 |
| Mikkilä, V | 1 |
| Telama, R | 1 |
| Viikari, JSA | 1 |
| Juonala, M | 1 |
| Raitakari, OT | 1 |
| Yu, S | 1 |
| Yu, YH | 1 |
| Tong, JH | 1 |
| Wang, L | 1 |
| Tin, EK | 1 |
| Chong, CC | 1 |
| Chan, SL | 1 |
| Lai, PB | 1 |
| To, KF | 1 |
| Lord, CC | 1 |
| Ferguson, D | 1 |
| Thomas, G | 1 |
| Brown, AL | 1 |
| Schugar, RC | 1 |
| Burrows, A | 1 |
| Gromovsky, AD | 1 |
| Betters, J | 1 |
| Neumann, C | 1 |
| Sacks, J | 1 |
| Marshall, S | 1 |
| Watts, R | 1 |
| Lee, RG | 1 |
| Crooke, RM | 1 |
| Graham, MJ | 1 |
| Lathia, JD | 1 |
| Sakaguchi, TF | 1 |
| Lehner, R | 4 |
| Haemmerle, G | 3 |
| Brown, JM | 1 |
| Fragoso, JM | 1 |
| Chen, G | 1 |
| Yu, D | 1 |
| Nian, X | 1 |
| Koenig, RJ | 1 |
| Xu, B | 1 |
| Sheng, L | 1 |
| Rau, M | 1 |
| Schattenberg, JM | 1 |
| Bantel, H | 1 |
| Pathil, A | 1 |
| Demir, M | 1 |
| Kluwe, J | 1 |
| Boettler, T | 1 |
| Geier, A | 1 |
| Jiang, L | 1 |
| Liu, Y | 1 |
| Shen, H | 1 |
| Weiss, SJ | 1 |
| Zhou, Y | 1 |
| Rui, L | 1 |
| Núñez-Torres, R | 1 |
| Macías, J | 1 |
| Mancebo, M | 1 |
| Frías, M | 1 |
| Dolci, G | 1 |
| Téllez, F | 1 |
| Merino, D | 1 |
| Merchante, N | 1 |
| Gómez-Mateos, J | 1 |
| Guaraldi, G | 1 |
| Rivero-Juárez, A | 1 |
| Pineda, JA | 1 |
| Real, LM | 1 |
| Yang, Z | 1 |
| Sun, J | 1 |
| Ji, H | 1 |
| Shi, XC | 1 |
| Du, ZY | 1 |
| Chen, LQ | 1 |
| Zhan, Q | 2 |
| Li, YY | 2 |
| Nie, YQ | 2 |
| Zhou, YJ | 2 |
| DU, YL | 1 |
| Sha, WH | 1 |
| Ronchetti, A | 1 |
| Prati, D | 1 |
| Pezzotta, MG | 1 |
| Tavian, D | 1 |
| Colombo, R | 1 |
| Callea, F | 1 |
| Colli, A | 1 |
| Magee, TR | 1 |
| Han, G | 1 |
| Cherian, B | 1 |
| Khorram, O | 1 |
| Ross, MG | 1 |
| Desai, M | 1 |
| Paraje, MG | 1 |
| Correa, SG | 1 |
| Renna, MS | 1 |
| Theumer, M | 1 |
| Sotomayor, CE | 1 |
| Kozlitina, J | 1 |
| Xing, C | 3 |
| Pertsemlidis, A | 1 |
| Cox, D | 1 |
| Pennacchio, LA | 1 |
| Boerwinkle, E | 1 |
| Pardina, E | 1 |
| Baena-Fustegueras, JA | 1 |
| Catalán, R | 1 |
| Galard, R | 1 |
| Lecube, A | 1 |
| Fort, JM | 1 |
| Allende, H | 1 |
| Vargas, V | 1 |
| Peinado-Onsurbe, J | 1 |
| Yamaguchi, T | 1 |
| Osumi, T | 1 |
| Kato, M | 1 |
| Higuchi, N | 1 |
| Enjoji, M | 1 |
| Kotronen, A | 4 |
| Johansson, LE | 1 |
| Johansson, LM | 2 |
| Roos, C | 1 |
| Westerbacka, J | 1 |
| Hamsten, A | 1 |
| Bergholm, R | 2 |
| Arkkila, P | 1 |
| Arola, J | 1 |
| Kiviluoto, T | 1 |
| Fisher, RM | 1 |
| Ehrenborg, E | 1 |
| Ridderstråle, M | 2 |
| Groop, L | 3 |
| Loos, RJ | 1 |
| Savage, DB | 2 |
| Peltonen, M | 2 |
| Rissanen, A | 3 |
| Chalasani, N | 1 |
| Kantartzis, K | 1 |
| Machann, J | 1 |
| Wagner, S | 1 |
| Schick, F | 1 |
| Fritsche, A | 1 |
| Stefan, N | 3 |
| Sentinelli, F | 2 |
| Dash, S | 1 |
| Yeo, GS | 1 |
| Leonetti, F | 1 |
| Capoccia, D | 1 |
| Incani, M | 2 |
| Iacovino, M | 1 |
| O'Rahilly, S | 1 |
| Baroni, MG | 2 |
| Charlton, M | 1 |
| Hoekstra, M | 1 |
| Li, Z | 1 |
| Kruijt, JK | 1 |
| Van Eck, M | 1 |
| Van Berkel, TJ | 1 |
| Kuiper, J | 1 |
| Radner, FP | 1 |
| Streith, IE | 1 |
| Schoiswohl, G | 2 |
| Kumari, M | 1 |
| Rechberger, G | 1 |
| Koefeler, HC | 1 |
| Eder, S | 1 |
| Schauer, S | 1 |
| Theussl, HC | 1 |
| Preiss-Landl, K | 1 |
| He, S | 1 |
| McPhaul, C | 1 |
| Garuti, R | 1 |
| Kinch, L | 1 |
| Grishin, NV | 1 |
| Chiu, HK | 1 |
| Qian, K | 1 |
| Ogimoto, K | 1 |
| Morton, GJ | 1 |
| Wisse, BE | 1 |
| Agrawal, N | 1 |
| McDonald, TO | 1 |
| Schwartz, MW | 1 |
| Dichek, HL | 1 |
| Tao, W | 1 |
| Deqin, Z | 1 |
| Yuhong, L | 1 |
| Hong, L | 1 |
| Zhanbiao, L | 1 |
| Chunfeng, Z | 1 |
| Limin, H | 1 |
| Xiumei, G | 1 |
| Al-Serri, A | 3 |
| Daly, AK | 4 |
| Galmozzi, E | 3 |
| Roviaro, G | 3 |
| Huang, J | 1 |
| Shi, SL | 1 |
| Lai, XB | 1 |
| Huang, HL | 1 |
| Cambuli, VM | 1 |
| Congiu, T | 1 |
| Matta, V | 1 |
| Pilia, S | 1 |
| Huang-Doran, I | 1 |
| Cossu, E | 1 |
| Loche, S | 1 |
| Butler, JL | 2 |
| Palmer, CD | 2 |
| Voight, BF | 2 |
| Bartuli, A | 1 |
| Del Menico, B | 2 |
| Alterio, A | 2 |
| Ko, JS | 1 |
| Rotman, Y | 1 |
| Koh, C | 1 |
| Zmuda, JM | 1 |
| Kleiner, DE | 1 |
| Liang, TJ | 1 |
| D'Adamo, E | 1 |
| Dykas, DJ | 2 |
| Zhang, CK | 2 |
| Bale, AE | 2 |
| Calí, AM | 1 |
| Narayan, D | 1 |
| Savoye, M | 2 |
| Lartaud, D | 1 |
| Eldrich, S | 1 |
| Cushman, SW | 1 |
| Zhao, H | 2 |
| Shulman, GI | 1 |
| Koutsari, C | 1 |
| Lazaridis, KN | 1 |
| Farrell, GC | 1 |
| Petit, JM | 2 |
| Guiu, B | 2 |
| Masson, D | 2 |
| Duvillard, L | 2 |
| Jooste, V | 2 |
| Buffier, P | 2 |
| Terriat, B | 1 |
| Bouillet, B | 2 |
| Brindisi, MC | 2 |
| Loffroy, R | 1 |
| Robin, I | 2 |
| Hillon, P | 2 |
| Cercueil, JP | 2 |
| Verges, B | 2 |
| Walker, R | 2 |
| Le, KA | 2 |
| Mahurkar, S | 1 |
| Vikman, S | 2 |
| Davis, JN | 2 |
| Weigensberg, MJ | 2 |
| Staiger, H | 1 |
| Ong, KT | 2 |
| Mashek, MT | 2 |
| Bu, SY | 2 |
| Dubuquoy, C | 2 |
| Robichon, C | 1 |
| Lasnier, F | 1 |
| Langlois, C | 1 |
| Dugail, I | 1 |
| Foufelle, F | 1 |
| Girard, J | 1 |
| Burnol, AF | 2 |
| Postic, C | 1 |
| Hu, FC | 1 |
| Yang, WS | 1 |
| Cai, T | 1 |
| Dufour, JF | 1 |
| Muellhaupt, B | 1 |
| Gerlach, T | 1 |
| Heim, M | 1 |
| Moradpour, D | 1 |
| Cerny, A | 1 |
| Malinverni, R | 1 |
| Kaddai, V | 1 |
| Bochud, M | 1 |
| Negro, F | 1 |
| Bochud, PY | 1 |
| Bowden, DW | 2 |
| Rotter, JI | 1 |
| Ziegler, J | 1 |
| Chen, YD | 1 |
| Haffner, S | 1 |
| Müller, T | 1 |
| Buch, S | 1 |
| Berg, T | 1 |
| Rumi, M | 1 |
| Dong, H | 1 |
| Czaja, MJ | 1 |
| Kim, LJ | 1 |
| Gudnason, V | 1 |
| Eiriksdottir, G | 1 |
| Garcia, ME | 1 |
| Launer, LJ | 1 |
| Nalls, MA | 1 |
| Mitchell, BD | 1 |
| Shuldiner, AR | 1 |
| Tomas, M | 1 |
| Hoffmann, U | 1 |
| Hwang, SJ | 1 |
| Massaro, JM | 1 |
| O'Donnell, CJ | 1 |
| Sahani, DV | 1 |
| Salomaa, V | 1 |
| Schadt, EE | 1 |
| Schwartz, SM | 1 |
| Siscovick, DS | 1 |
| Fox, CS | 1 |
| Zimmer, V | 1 |
| Liu, L | 1 |
| Shao, JH | 1 |
| Wang, K | 1 |
| Hua, FZ | 1 |
| Wang, SP | 2 |
| Alvarez, F | 1 |
| Casavant, S | 1 |
| Gauthier, N | 1 |
| Abed, L | 1 |
| Soni, KG | 1 |
| Yang, G | 1 |
| Ballestri, S | 1 |
| Carulli, L | 1 |
| Loria, P | 1 |
| Trépo, E | 1 |
| Pradat, P | 1 |
| Potthoff, A | 1 |
| Momozawa, Y | 1 |
| Quertinmont, E | 1 |
| Gustot, T | 1 |
| Lemmers, A | 1 |
| Berthillon, P | 1 |
| Amininejad, L | 1 |
| Chevallier, M | 1 |
| Schlué, J | 1 |
| Kreipe, H | 1 |
| Devière, J | 1 |
| Manns, M | 1 |
| Trépo, C | 1 |
| Sninsky, J | 1 |
| Wedemeyer, H | 1 |
| Franchimont, D | 1 |
| Moreno, C | 1 |
| Cox, AJ | 1 |
| Wing, MR | 1 |
| Hightower, RC | 1 |
| Smith, SC | 1 |
| Freedman, BI | 1 |
| Romero-Gómez, M | 2 |
| Serfaty, L | 1 |
| Castera, L | 1 |
| Marcellin, P | 1 |
| Wang, CW | 1 |
| Lin, HY | 1 |
| Shin, SJ | 1 |
| Li, SS | 1 |
| Falleti, E | 1 |
| Fabris, C | 1 |
| Cmet, S | 1 |
| Cussigh, A | 1 |
| Bitetto, D | 1 |
| Fontanini, E | 1 |
| Fornasiere, E | 1 |
| Bignulin, S | 1 |
| Fumolo, E | 1 |
| Bignulin, E | 1 |
| Pirisi, M | 1 |
| Toniutto, P | 1 |
| Gambert, P | 1 |
| Leathart, JB | 2 |
| Patch, J | 1 |
| Zappa, MA | 1 |
| Shimada, T | 1 |
| Horikawa, T | 1 |
| Ikeya, Y | 1 |
| Matsuo, H | 1 |
| Kinoshita, K | 1 |
| Taguchi, T | 1 |
| Ichinose, K | 1 |
| Takahashi, K | 1 |
| Aburada, M | 1 |
| Quiroga, AD | 3 |
| Pihlajamäki, J | 1 |
| Kuulasmaa, T | 1 |
| Kaminska, D | 1 |
| Simonen, M | 1 |
| Kärjä, V | 1 |
| Grönlund, S | 1 |
| Käkelä, P | 1 |
| Pääkkönen, M | 1 |
| Kainulainen, S | 1 |
| Punnonen, K | 1 |
| Kuusisto, J | 1 |
| Gylling, H | 2 |
| Laakso, M | 1 |
| Chang, CY | 1 |
| Pakstis, AJ | 1 |
| Demori, I | 1 |
| De Matteis, R | 1 |
| Lanni, A | 1 |
| Stojkovic, I | 1 |
| Makkonen, J | 2 |
| Krauss, RM | 1 |
| Melander, O | 1 |
| Chen, W | 1 |
| Chang, B | 1 |
| Saha, P | 1 |
| Hartig, SM | 1 |
| Li, L | 3 |
| Reddy, VT | 1 |
| Yang, Y | 1 |
| Yechoor, V | 1 |
| Mancini, MA | 1 |
| Chan, L | 1 |
| Fuchs, CD | 1 |
| Kumari, P | 1 |
| Pollheimer, MJ | 1 |
| Stojakovic, T | 1 |
| Scharnagl, H | 1 |
| Gumhold, J | 1 |
| Silbert, D | 1 |
| Duseja, A | 1 |
| Aggarwal, R | 1 |
| Adams, LA | 1 |
| Marsh, JA | 1 |
| Ayonrinde, OT | 1 |
| Olynyk, JK | 1 |
| Ang, WQ | 1 |
| Beilin, LJ | 1 |
| Mori, T | 1 |
| Palmer, LJ | 1 |
| Oddy, WW | 1 |
| Lye, SJ | 1 |
| Pennell, CE | 1 |
| Miksztowicz, V | 1 |
| Lucero, D | 1 |
| Zago, V | 1 |
| Cacciagiú, L | 1 |
| Lopez, G | 1 |
| Gonzalez Ballerga, E | 1 |
| Sordá, J | 1 |
| Fassio, E | 1 |
| Schreier, L | 1 |
| Berg, G | 1 |
| Ampuero, J | 1 |
| Clark, PJ | 1 |
| Thompson, AJ | 1 |
| Zhu, Q | 1 |
| Vock, DM | 1 |
| Zhu, M | 1 |
| Patel, K | 1 |
| Harrison, SA | 1 |
| Naggie, S | 1 |
| Ge, D | 1 |
| Tillmann, HL | 2 |
| Urban, TJ | 1 |
| Shianna, K | 1 |
| Fellay, J | 1 |
| Goodman, Z | 1 |
| Noviello, S | 1 |
| Pedicone, LD | 1 |
| Afdhal, N | 1 |
| Sulkowski, M | 1 |
| Albrecht, JK | 1 |
| Goldstein, DB | 1 |
| McHutchison, JG | 1 |
| Muir, AJ | 1 |
| Graff, M | 1 |
| North, KE | 1 |
| Franceschini, N | 1 |
| Reiner, AP | 1 |
| Feitosa, M | 1 |
| Gordon-Larsen, P | 1 |
| Wojczynski, MK | 1 |
| Ventura, EE | 1 |
| Marotto, K | 1 |
| Rutter, K | 1 |
| Beinhardt, S | 1 |
| Scherzer, TM | 1 |
| Stadlmayr, A | 1 |
| Hofer, H | 1 |
| Wrba, F | 1 |
| Steindl-Munda, P | 1 |
| Krebs, M | 1 |
| Datz, C | 1 |
| Lian, J | 2 |
| Wei, E | 1 |
| Di Pardo, A | 1 |
| van der Veen, J | 1 |
| Sipione, S | 1 |
| Maggioni, P | 1 |
| Piperno, A | 1 |
| Pelucchi, S | 1 |
| Mariani, R | 1 |
| Sumida, Y | 1 |
| Umemura, A | 1 |
| Matsuo, K | 1 |
| Takahashi, M | 1 |
| Takamura, T | 1 |
| Hashimoto, E | 1 |
| Kawanaka, M | 1 |
| Watanabe, S | 1 |
| Kawata, S | 1 |
| Imai, Y | 1 |
| Kokubo, M | 1 |
| Park, H | 1 |
| Tanaka, H | 1 |
| Tajima, K | 1 |
| Yamada, R | 1 |
| Kuo, YT | 1 |
| Lin, TH | 1 |
| Chen, WL | 1 |
| Lee, HM | 1 |
| Canavesi, E | 1 |
| Santos, A | 1 |
| Silander, K | 1 |
| Lundbom, J | 1 |
| Fielding, BA | 1 |
| Rembeck, K | 1 |
| Lagging, M | 1 |
| Christensen, PB | 1 |
| Färkkilä, M | 1 |
| Langeland, N | 1 |
| Buhl, MR | 1 |
| Pedersen, C | 1 |
| Mørch, K | 1 |
| Norkrans, G | 1 |
| Hellstrand, K | 1 |
| Lindh, M | 1 |
| Pirazzi, C | 1 |
| Burza, MA | 2 |
| Westin, J | 1 |
| Zeng, Z | 1 |
| O'Neil, M | 1 |
| Zhao, J | 1 |
| Whitener, M | 1 |
| Yu-Jui Wan, Y | 1 |
| Mitchell, EK | 1 |
| Handler, M | 1 |
| Weinman, SA | 1 |
| Garrett, ME | 1 |
| Abdelmalek, MF | 1 |
| Ashley-Koch, A | 1 |
| Hauser, MA | 1 |
| Moylan, CA | 1 |
| Pang, H | 1 |
| Tian, Z | 1 |
| Ku, HC | 1 |
| Peng, XE | 1 |
| Wu, YL | 1 |
| Lin, SW | 1 |
| Lu, QQ | 1 |
| Hu, ZJ | 1 |
| Lin, X | 1 |
| Ginanni Corradini, S | 1 |
| Lallukka, S | 1 |
| Perttilä, J | 1 |
| Han, LK | 1 |
| Zheng, YN | 1 |
| Xu, BJ | 1 |
| Okuda, H | 1 |
| Kimura, Y | 1 |
| Zhang, XG | 1 |
| Chen, YZ | 1 |
| Lei, H | 1 |
| Wang, ZB | 1 |
| Sabuncu, T | 1 |
| Nazligul, Y | 1 |
| Karaoglanoglu, M | 1 |
| Ucar, E | 1 |
| Kilic, FB | 1 |
| Srinivasan, R | 1 |
| Hadzić, N | 1 |
| Fischer, J | 1 |
| Knisely, AS | 1 |
| Marzocchi, R | 1 |
| Villanova, N | 1 |
| Werner, A | 1 |
| Havinga, R | 1 |
| Bos, T | 1 |
| Bloks, VW | 1 |
| Kuipers, F | 1 |
| Verkade, HJ | 1 |
| Xie, ML | 1 |
| Zhu, LJ | 1 |
| Gu, ZL | 1 |
| Hussein, O | 1 |
| Grosovski, M | 1 |
| Schlesinger, S | 1 |
| Szvalb, S | 1 |
| Assy, N | 1 |
| Rahman, SM | 1 |
| Schroeder-Gloeckler, JM | 1 |
| Janssen, RC | 1 |
| Jiang, H | 1 |
| Qadri, I | 1 |
| Maclean, KN | 1 |
| Friedman, JE | 1 |
| Chung, C | 1 |
| Doll, JA | 1 |
| Gattu, AK | 1 |
| Shugrue, C | 1 |
| Cornwell, M | 1 |
| Fitchev, P | 1 |
| Crawford, SE | 1 |
| Reid, BN | 1 |
| Ables, GP | 1 |
| Otlivanchik, OA | 1 |
| Blaner, WS | 1 |
| Goldberg, IJ | 1 |
| Schwabe, RF | 1 |
| Chua, SC | 1 |
| Huang, LS | 1 |
| Ammon, HP | 1 |
| Estler, CJ | 1 |
| Morii, S | 1 |
| Itakura, H | 1 |
| Murase, T | 1 |
| Takaku, F | 1 |
| Kishino, Y | 1 |
| Abe, M | 1 |
| Reue, K | 2 |
| Doolittle, MH | 2 |
| Levin, TL | 1 |
| Berdon, WE | 1 |
| Tang, HB | 1 |
| Haller, JO | 1 |
| Rehnmark, S | 1 |
| Giometti, CS | 1 |
| Slavin, BG | 1 |
| Boldrini, R | 1 |
| Castro, M | 1 |
| Marcellini, M | 1 |
| Piemonte, F | 1 |
| Bosman, C | 1 |
| Cenedella, RJ | 1 |
| Hettwer, H | 1 |
| Hansen, W | 1 |
| Suzuki, Y | 1 |
| Kawai, S | 1 |
| Kobayashi, A | 1 |
| Ohbe, Y | 1 |
| Endo, H | 1 |
| Murakoshi, M | 2 |
| Suemizu, H | 1 |
| Watanabe, K | 2 |
| Langner, CA | 1 |
| Birkenmeier, EH | 1 |
| Ben-Zeev, O | 1 |
| Schotz, MC | 1 |
| Sweet, HO | 1 |
| Davisson, MT | 1 |
| Gordon, JI | 1 |
| Misawa, M | 1 |
| Archibald, RW | 1 |
| Orton, CC | 1 |
| Gupalo, EE | 1 |
| Bondar', ZA | 1 |
| Podymova, SD | 1 |
| Zolotnitskaia, RP | 1 |
| Saluznía, AI | 1 |
| Plotnikova, NM | 1 |
| Chaun, H | 1 |
| King, DM | 1 |
| Gofton, JP | 1 |
| Sutherland, WH | 1 |
| Bogoch, A | 1 |
| Bourgeois, C | 1 |
| Olson, L | 1 |
| Comer, D | 1 |
| Evans, H | 1 |
| Keschamras, N | 1 |
| Cotton, R | 1 |
| Grossman, R | 1 |
| Smith, T | 1 |
| Bar-On, H | 1 |
| Stein, O | 1 |
| Stein, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Efficacy and Tolerability of Docosahexaenoic Acid (DHA) on Children Affected by Nonalcoholic Fatty Liver Disease (NAFLD).[NCT00885313] | Phase 1/Phase 2 | 60 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Prevalence, Clinicopathological Characteristics, Biomarkers and Genetics of Nonalcoholic Steatohepatitis in Taiwanese Children[NCT00274183] | 614 participants (Actual) | Observational | 2006-01-31 | Completed | |||
| Low Glycemic Index Dietary Intervention Program in Nonalcoholic Fatty Liver Disease - A Randomized Controlled Trial[NCT00868933] | 159 participants (Actual) | Interventional | 2009-02-28 | Completed | |||
| An Observational Study of the Clinical Characteristics and Disease Progression of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype[NCT01528917] | 49 participants (Actual) | Observational | 2011-06-30 | Completed | |||
| A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men[NCT04186260] | 39 participants (Anticipated) | Interventional | 2023-12-01 | Recruiting | |||
| Study of Metabolism Influence in Human Alcoholic Liver Disease[NCT01122797] | 658 participants (Actual) | Observational | 2003-01-31 | Completed | |||
| Optimizing the Beneficial Health Effects of Exercise for Diabetes: Focus on the Liver![NCT01317576] | 81 participants (Actual) | Interventional | 2011-03-31 | Completed | |||
| The Role of the PNPLA3, TM6SF2 and MBOAT7 Genetic Variants in the Response to Silybin-phospholipid Complex, Vitamin D and Vitamin E Based Therapy for Non-alcoholic Fatty Liver Disease Patients[NCT04640324] | 92 participants (Actual) | Interventional | 2017-01-16 | Completed | |||
| Intra-Abdominal Fat and Risk of Disease in Adolescents[NCT00697580] | 104 participants (Actual) | Interventional | 2005-05-31 | Completed | |||
| Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth[NCT00693511] | 45 participants (Actual) | Interventional | 2007-10-31 | Completed | |||
| Genetic-specific Effects of Fructose on Liver Lipogenesis[NCT03783195] | 15 participants (Actual) | Interventional | 2019-01-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
28 reviews available for 1-anilino-8-naphthalenesulfonate and Liver Steatosis
| Article | Year |
|---|---|
Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Apoptosis; Carcinoma, Hepatocellular; Diet, High-Fat; Dis | 2020 |
Association of PNPLA3 rs738409 polymorphism with liver steatosis but not with cirrhosis in patients with HBV infection: Systematic review with meta-analysis.
Topics: Fatty Liver; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Lipase; Liver Cirrhosis; Me | 2018 |
Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Black People; Chondroitin Sulfate Proteoglycans; | 2013 |
[Genetic predisposition related to non-alcoholic fatty liver disease].
Topics: Fatty Liver; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Lipase; Membr | 2013 |
The genetics of NAFLD.
Topics: Disease Progression; Epigenomics; Fatty Liver; Genome-Wide Association Study; Humans; Lipase; Membra | 2013 |
PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease.
Topics: Age Factors; Animals; Fatty Liver; Gene Frequency; Genetic Predisposition to Disease; Genetic Variat | 2013 |
PNPLA3 I148M polymorphism and progressive liver disease.
Topics: Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Disease Progression; Fatty Liver; Fatty Liver, A | 2013 |
Obesity-associated nonalcoholic fatty liver disease.
Topics: Adult; Bariatric Surgery; Child; Fatty Liver; Female; Humans; Insulin Resistance; Lipase; Male; Memb | 2014 |
Host genetic variants in obesity-related nonalcoholic fatty liver disease.
Topics: Adipogenesis; Apolipoprotein C-III; Carrier Proteins; Fatty Liver; Genetic Association Studies; Hemo | 2014 |
Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome.
Topics: Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Metabolic S | 2014 |
Pediatric fatty liver disease: role of ethnicity and genetics.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Age of Onset; Apolipoprotein C-III; Child; Ethnici | 2014 |
PNPLA3 rs738409 Polymorphism Associated with Hepatic Steatosis and Advanced Fibrosis in Patients with Chronic Hepatitis C Virus: A Meta-Analysis.
Topics: Asian People; Fatty Liver; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Membrane Proteins; | 2016 |
Chanarin-Dorfman syndrome: deficiency in CGI-58, a lipid droplet-bound coactivator of lipase.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adipocytes; Carrier Proteins; Enzyme Activation; Fatty | 2009 |
Liver fat in the pathogenesis of insulin resistance and type 2 diabetes.
Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Fatty Liver; Glucose; Humans; Insulin; Insulin Resistance | 2010 |
[Nonalcoholic fatty liver disease].
Topics: Diet; Fatty Liver; Humans; Inflammation Mediators; Insulin Resistance; Lipase; Membrane Proteins; Me | 2010 |
Dissociation between fatty liver and insulin resistance: the role of adipose triacylglycerol lipase.
Topics: Adipose Tissue; Animals; Fatty Liver; Humans; Insulin Resistance; Lipase; Models, Biological | 2011 |
Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease.
Topics: Adult; Alanine Transaminase; Child; Fatty Liver; Female; Genetic Predisposition to Disease; Heterozy | 2011 |
Regulation of lipid droplets by autophagy.
Topics: Adipocytes; Adipogenesis; Animals; Autophagy; Fatty Liver; Hepatocytes; Humans; Lipase; Lipid Metabo | 2011 |
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Blood Glucose; Case-Control St | 2011 |
Genetics in liver disease: new concepts.
Topics: Autoimmune Diseases; Cholestasis; Fatty Liver; Genetic Predisposition to Disease; Genome-Wide Associ | 2011 |
Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease.
Topics: Animals; Cytokines; Disease Progression; Fatty Liver; Female; Genetic Predisposition to Disease; Gen | 2011 |
Liver triacylglycerol lipases.
Topics: Animals; Autophagy; Diabetes Mellitus, Type 2; Esterases; Fatty Liver; Hepatocytes; Humans; Lipase; | 2012 |
[Influence of non-alcoholic fatty liver disease on cardiovascular disease].
Topics: Apolipoprotein C-III; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Chol | 2012 |
Genetic-related and carbohydrate-related factors affecting liver fat accumulation.
Topics: Animals; Apolipoprotein C-III; Carrier Proteins; Diet; Dietary Carbohydrates; Energy Intake; Fatty L | 2012 |
The genetic epidemiology of nonalcoholic fatty liver disease: toward a personalized medicine.
Topics: Epigenomics; Fatty Liver; Female; Genetic Loci; Genetic Predisposition to Disease; Genetic Variation | 2012 |
PNPLA3 I148M variant and hepatocellular carcinoma: a common genetic variant for a rare disease.
Topics: Carcinoma, Hepatocellular; Fatty Liver; Genetic Markers; Hepatitis, Chronic; Humans; Lipase; Liver C | 2013 |
Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH): treatment.
Topics: Antioxidants; Cholagogues and Choleretics; Cytoprotection; Enzyme Inhibitors; Fatty Liver; Humans; H | 2004 |
Naturally occurring mutations in mice affecting lipid transport and metabolism.
Topics: Animals; Biological Transport; Cholesterol; Fatty Acids; Fatty Liver; Lipase; Lipid Metabolism; Mice | 1996 |
9 trials available for 1-anilino-8-naphthalenesulfonate and Liver Steatosis
| Article | Year |
|---|---|
Four-Week Omega-3 Supplementation in Carriers of the Prosteatotic PNPLA3 p.I148M Genetic Variant: An Open-Label Study.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Dietary Supplements; Elasticity Imaging Techniques | 2019 |
Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.
Topics: Actinin; Adult; Age Factors; Aged; Alanine Transaminase; Asian People; Aspartate Aminotransferases; | 2013 |
The I148M variant of PNPLA3 reduces the response to docosahexaenoic acid in children with non-alcoholic fatty liver disease.
Topics: Child; Child, Preschool; Docosahexaenoic Acids; Fatty Liver; Female; Humans; Lipase; Male; Membrane | 2013 |
Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Alleles; Asian People; Body Mass Index; Child; Fat | 2014 |
Conjugated linoleic acid alters growth performance, tissue lipid deposition, and fatty acid composition of darkbarbel catfish (Pelteobagrus vachelli).
Topics: Analysis of Variance; Animals; Aquaculture; Catfishes; Dietary Fats; Fatty Acids; Fatty Liver; Fish | 2015 |
Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans.
Topics: Adult; Body Mass Index; Diet, Reducing; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Female; | 2012 |
PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection.
Topics: Adult; Alleles; Antiviral Agents; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; | 2012 |
A common variant in the peroxisome proliferator-activated receptor-γ coactivator-1α gene is associated with nonalcoholic fatty liver disease in obese children.
Topics: Adolescent; Alleles; Body Mass Index; Child; Cohort Studies; Fatty Liver; Female; Genetic Associatio | 2013 |
The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis.
Topics: Adult; Anti-Obesity Agents; Appetite Depressants; Cyclobutanes; Enzyme Inhibitors; Fatty Liver; Fema | 2003 |
225 other studies available for 1-anilino-8-naphthalenesulfonate and Liver Steatosis
| Article | Year |
|---|---|
Role of PNPLA3 in the Assessment and Monitoring of Hepatic Steatosis and Fibrosis in Patients with Chronic Hepatitis C Infection Who Achieved a Sustained Virologic Response.
Topics: Antiviral Agents; Fatty Liver; Genotype; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Memb | 2021 |
The PNPLA3 variant I148M reveals protective effects toward hepatocellular carcinoma in mice via restoration of omega-3 polyunsaturated fats.
Topics: Acyltransferases; Alcohol Drinking; Animals; Carcinoma, Hepatocellular; Docosahexaenoic Acids; Fatty | 2022 |
Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants.
Topics: Antiviral Agents; Fatty Liver; Fibrosis; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; H | 2022 |
Thymoquinone and quercetin protect against hepatic steatosis in association with SIRT1/AMPK stimulation and regulation of autophagy, perilipin-2, and cytosolic lipases.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Fatty Liver; Lipase; Lipid Metabolism; Liver; Per | 2023 |
N-end Rule-Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage.
Topics: Acyltransferases; Adipose Tissue; Animals; Fatty Liver; Lipase; Lipolysis; Mice; Obesity; Proteasome | 2023 |
Hydroxysteroid 17β-dehydrogenase 11 accumulation on lipid droplets promotes ethanol-induced cellular steatosis.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Ethanol; Fatty Liver; Lipase; Lipid Droplets; Lipid Metab | 2023 |
ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Enterocytes; Fatty Liver; Female; Homeostasis | 2019 |
Association between PNPLA3[G]/I148M variant, steatosis and fibrosis stage in hepatitis C virus - genetic matters.
Topics: Antiviral Agents; Disease Progression; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Interferon | 2019 |
Risk of chemotherapy-associated liver injury (CALI) in PNPLA3 p.148M allele carriers: Preliminary results of a transient elastography-based study.
Topics: Acyltransferases; Aged; Alleles; Antineoplastic Agents; Elasticity Imaging Techniques; Fatty Liver; | 2020 |
A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Diabetes Mellitus; Dyslipid | 2020 |
PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression.
Topics: Acyltransferases; Fatty Liver; Hepatitis C, Chronic; Humans; Interferons; Lipase; Liver Cirrhosis; M | 2022 |
The Patatin-Like Phospholipase Domain Containing Protein 7 Facilitates VLDL Secretion by Modulating ApoE Stability.
Topics: Animals; Apolipoproteins E; Cell Line, Tumor; Endoplasmic Reticulum; Fatty Liver; Female; Gene Knock | 2020 |
The influence of gene-chronic hepatitis C virus infection on hepatic fibrosis and steatosis.
Topics: Adult; Aged; Brazil; Carrier Proteins; Fatty Liver; Female; Genetic Association Studies; Genotype; H | 2020 |
Creb-Pgc1α pathway modulates the interaction between lipid droplets and mitochondria and influences high fat diet-induced changes of lipid metabolism in the liver and isolated hepatocytes of yellow catfish.
Topics: Animals; Catfishes; CREB-Binding Protein; Diet, High-Fat; Fatty Acids; Fatty Liver; Hep G2 Cells; He | 2020 |
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.
Topics: Animals; Autophagy; Disease Models, Animal; Fatty Liver; Female; Gene Expression Regulation; GTP Pho | 2020 |
Adipose-specific knockout of ubiquitin-conjugating enzyme E2L6 (Ube2l6) reduces diet-induced obesity, insulin resistance, and hepatic steatosis.
Topics: Adipocytes; Adipogenesis; Animals; Diet, High-Fat; Fatty Liver; Gene Knockout Techniques; Humans; In | 2021 |
Associations of Nutrient Intake Changes During Childhood with Adolescent Hepatic Fat: The Exploring Perinatal Outcomes Among CHildren Study.
Topics: Adolescent; Adolescent Behavior; Child; Child Behavior; Diet; Diet Surveys; Fatty Liver; Female; Gen | 2021 |
Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Topics: Adipose Tissue, White; Animals; Body Weight; Diet, High-Fat; Fatty Liver; Feeding Behavior; Glucose; | 2017 |
Mutant PNPLA3 I148M protein as pharmacological target for liver disease.
Topics: Fatty Liver; Humans; Lipase; Mutant Proteins | 2017 |
Genetic polymorphisms associated with fatty liver disease and fibrosis in HIV positive patients receiving combined antiretroviral therapy (cART).
Topics: Acyltransferases; Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Anti-Retrovi | 2017 |
A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis.
Topics: Cell Line, Tumor; Cholesterol Esters; Diacylglycerol O-Acyltransferase; Fatty Liver; Gene Expression | 2017 |
Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption.
Topics: Animals; Antioxidants; Area Under Curve; Diet, High-Fat; Fatty Acids, Nonesterified; Fatty Liver; Fe | 2018 |
Impact of PNPLA3 and IFNL3 polymorphisms on hepatic steatosis in Asian patients with chronic hepatitis C.
Topics: Adult; Aged; Alleles; Asian People; Fatty Liver; Female; Genetic Association Studies; Genetic Predis | 2017 |
CD18 deficiency improves liver injury in the MCD model of steatohepatitis.
Topics: Adipose Tissue; Animals; CD18 Antigens; Choline; Cytokines; Disease Models, Animal; Fatty Liver; Hep | 2017 |
Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake.
Topics: Adipose Tissue, White; Animals; Diet, Western; Fatty Acids; Fatty Liver; Gene Expression Regulation, | 2017 |
The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Brazil; DNA; Fatty Liver; Female; Gene Frequency; Genotype; | 2017 |
Donor PNPLA3 rs738409 genotype is a risk factor for graft steatosis. A post-transplant biopsy-based study.
Topics: Adiposity; Adult; Allografts; Biopsy; Body Mass Index; Diabetes Mellitus; Fatty Liver; Female; Genot | 2018 |
Impact of patatin-like phospholipase domain containing 3 rs738409 G/G genotype on hepatic decompensation and mortality in patients with portal hypertension.
Topics: Adult; Aged; Cross-Sectional Studies; Fatty Liver; Female; Genetic Predisposition to Disease; Genoty | 2018 |
PNPLA3 rs738409 Polymorphism Predicts Development and Severity of Hepatic Steatosis but Not Metabolic Syndrome in Celiac Disease.
Topics: Adolescent; Adult; Alleles; Celiac Disease; Diet, Gluten-Free; Fatty Liver; Female; Genetic Predispo | 2018 |
Dissociation of Fatty Liver and Insulin Resistance in I148M PNPLA3 Carriers: Differences in Diacylglycerol (DAG) FA18:1 Lipid Species as a Possible Explanation.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; Diglycerides; Fatty Liver; Female; Gen | 2018 |
No effect of MTP polymorphisms on PNPLA3 in HCV-correlated steatosis.
Topics: Adult; Anthropometry; Biopsy; Carrier Proteins; Fatty Liver; Female; Genetic Predisposition to Disea | 2018 |
Adipocyte GR Inhibits Healthy Adipose Expansion Through Multiple Mechanisms in Cushing Syndrome.
Topics: Adipocytes; Adipose Tissue; Adult; Animals; Case-Control Studies; Cushing Syndrome; Disease Models, | 2019 |
Association of Bright Liver With the PNPLA3 I148M Gene Variant in 1-Year-Old Toddlers.
Topics: Fatty Liver; Female; Genotype; Humans; Infant; Lipase; Liver; Male; Membrane Proteins; Ultrasonograp | 2019 |
Adipose HuR protects against diet-induced obesity and insulin resistance.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Cell Enlargement; Diet, High-Fat; ELAV-L | 2019 |
Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Black People; Fatty Liver; Female; Gene Frequency | 2013 |
Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity.
Topics: Adult; Alleles; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 1; Fatty Liver; Female; F | 2013 |
Susceptibility and gene interaction study of the angiotensin II type 1 receptor (AGTR1) gene polymorphisms with non-alcoholic fatty liver disease in a multi-ethnic population.
Topics: Asian People; Epistasis, Genetic; Fatty Liver; Genetic Predisposition to Disease; Genotype; Haplotyp | 2013 |
A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.
Topics: Adult; Alanine Transaminase; Apolipoprotein C-III; Aspartate Aminotransferases; Body Mass Index; Cro | 2013 |
Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B.
Topics: Adult; Alcoholism; Cohort Studies; Disease Progression; Fatty Liver; Female; Genetic Predisposition | 2013 |
Common genetic variants and nonalcoholic Fatty liver disease.
Topics: Adaptor Proteins, Signal Transducing; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; | 2013 |
Genetic variation in the patatin-like phospholipase domain-containing protein-3 (PNPLA-3) gene in Asian Indians with nonalcoholic fatty liver disease.
Topics: Adult; Anthropometry; Asian People; Blood Glucose; Blood Pressure; Case-Control Studies; Cholesterol | 2013 |
Last blood check before passing: does alcohol prevent fibrosis?
Topics: Fatty Liver; Fatty Liver, Alcoholic; Female; Humans; Lipase; Male; Membrane Proteins; Polymorphism, | 2013 |
Response to Doganay et al.
Topics: Fatty Liver; Fatty Liver, Alcoholic; Female; Humans; Lipase; Male; Membrane Proteins; Polymorphism, | 2013 |
Genetic and clinical markers of elevated liver fat content in overweight and obese Hispanic children.
Topics: Adolescent; Alanine Transaminase; Alleles; Anthropometry; Apolipoprotein C-III; Aspartate Aminotrans | 2013 |
Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C.
Topics: Abdominal Fat; Adult; Aged; Aged, 80 and over; Apolipoprotein C-III; Fatty Liver; Female; Genotype; | 2013 |
Oxidized fatty acids: A potential pathogenic link between fatty liver and type 2 diabetes in obese adolescents?
Topics: Adolescent; Biomarkers; Child; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Liver; Female; Glucose; | 2014 |
Weight loss allows the dissection of the interaction between abdominal fat and PNPLA3 (adiponutrin) in the liver damage of obese children.
Topics: Abdominal Fat; Alanine Transaminase; Alleles; Body Mass Index; Child; Fatty Liver; Genotype; Heteroz | 2013 |
Patatin-like phospholipase domain-containing protein 3 rs738409-G in recipients of liver transplants is a risk factor for graft steatosis.
Topics: Adult; Aged; Fatty Liver; Female; Genotype; Genotyping Techniques; Humans; Lipase; Liver; Liver Tran | 2013 |
Adipocyte size is associated with NAFLD independent of obesity, fat distribution, and PNPLA3 genotype.
Topics: Adipocytes; Adult; Body Composition; Body Fat Distribution; Cross-Sectional Studies; Fatty Liver; Fe | 2013 |
Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Topics: Animals; Choline Deficiency; Disease Models, Animal; Endotoxemia; Fatty Liver; Female; Lipase; Lipop | 2014 |
Circulating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity.
Topics: Adolescent; Adult; Aged; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; Humans; I | 2014 |
PNPLA3 GG genotype and carotid atherosclerosis in patients with non-alcoholic fatty liver disease.
Topics: Adult; Aged; Alleles; Carotid Arteries; Carotid Artery Diseases; Fatty Liver; Female; Genetic Associ | 2013 |
[Polymorphism rs738409 in PNPLA3 is associated with inherited susceptibility to non-alcoholic fatty liver disease].
Topics: Adolescent; Adult; Aged; Alleles; Case-Control Studies; Fatty Liver; Female; Gene Frequency; Genetic | 2013 |
PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Case-Control Studies; Demography; Fatty Liver; Female; Follow-Up St | 2013 |
Fibrates reduce triacylglycerol content by upregulating adipose triglyceride lipase in the liver of rats.
Topics: Animals; Bezafibrate; Clofibric Acid; Fatty Liver; Fenofibrate; Lipase; Lipid Peroxidation; Liver; M | 2013 |
No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV.
Topics: Adult; Aged; Asian People; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; Hepaciv | 2013 |
Serum TAG analysis differentiates between genetic and obesity-associated NAFLD.
Topics: Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Obesity; Triglycerides | 2014 |
PNPLA3 gene polymorphism accounts for fatty liver in community subjects without metabolic syndrome.
Topics: Adult; Diet; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Metabolic Syndrome; Middl | 2014 |
Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats.
Topics: Animals; CD36 Antigens; Diacylglycerol O-Acyltransferase; Diet, High-Fat; Dietary Fats; Fatty Liver; | 2014 |
3,5-diiodo-L-thyronine modifies the lipid droplet composition in a model of hepatosteatosis.
Topics: Animals; Cell Line, Tumor; Diiodothyronines; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fatty | 2014 |
Impact of comorbid hepatic steatosis on treatment of chronic hepatitis C in Japanese patients and the relationship with genetic polymorphism of IL28B, PNPLA3 and LDL receptor.
Topics: Aged; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Lipase; Logistic | 2014 |
Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
Topics: Adipogenesis; Adipose Tissue; Animals; Choline; Disease Models, Animal; Fatty Acids; Fatty Acids, No | 2014 |
Commentary: dissecting the PNPLA3 association with liver fat and stiffness, and interaction with diet.
Topics: Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Non-alcoholic Fatty Liver Disease | 2014 |
Commentary: dissecting the PNPLA3 association with liver fat and stiffness, and interaction with diet - authors' reply.
Topics: Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Non-alcoholic Fatty Liver Disease | 2014 |
Risk factors for fatty liver in the Multicenter AIDS Cohort Study.
Topics: Anti-HIV Agents; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Fatty Liver; Genetic | 2014 |
PNPLA3 I148M polymorphism is associated with elevated alanine transaminase levels in Mexican Indigenous and Mestizo populations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alleles; Fatty Liver; Female; Gene | 2014 |
Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity.
Topics: Adiposity; Age Factors; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cytochrome | 2014 |
Hepatic steatosis and PNPLA3 I148M variant are associated with serum Fetuin-A independently of insulin resistance.
Topics: Adiponectin; alpha-2-HS-Glycoprotein; Cross-Sectional Studies; Fatty Acids, Nonesterified; Fatty Liv | 2014 |
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Fatty Acids; Fatty Liver; Female; Gene Knock- | 2015 |
NAFLD. PNPLA3 variant and hepatic steatosis.
Topics: Fatty Liver; Genetic Variation; Humans; Lipase; Membrane Proteins; Non-alcoholic Fatty Liver Disease | 2014 |
Deciphering the role of ω3 fatty acids in nonalcoholic steatohepatitis.
Topics: Fatty Liver; Female; Genotype; Humans; Lipase; Liver; Male; Membrane Proteins; Pediatric Obesity; Po | 2014 |
PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease.
Topics: Adult; Alleles; Body Mass Index; Fatty Liver; Female; Humans; Life Style; Lipase; Liver; Male; Membr | 2015 |
PNPLA3 I148M variant is associated with metabolic stress-response phenotype in patients with nonalcoholic fatty liver disease.
Topics: Animals; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins | 2015 |
Interaction between PNPLA3 I148M variant and age at infection in determining fibrosis progression in chronic hepatitis C.
Topics: Adolescent; Adult; Age Factors; Aged; Disease Progression; Fatty Liver; Gene Frequency; Genetic Pred | 2014 |
Patatin-like phospholipase domain-containing protein 3 and liver disease: opportunities to unravel mechanisms underlying statistical associations.
Topics: Animals; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins | 2015 |
Novel association between a nonsynonymous variant (R270H) of the G-protein-coupled receptor 120 and liver injury in children and adolescents with obesity.
Topics: Adipose Tissue; Adolescent; Alanine Transaminase; Alleles; Child; Child, Preschool; Fatty Acids, Uns | 2014 |
The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients.
Topics: Body Weight; Carcinoma, Hepatocellular; Fatty Liver; Female; Hepatitis B, Chronic; Humans; Iron; Lip | 2015 |
The role of circulating lipoprotein lipase and adiponectin on the particle size of remnant lipoproteins in patients with diabetes mellitus and metabolic syndrome.
Topics: Adiponectin; Adult; Case-Control Studies; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; | 2015 |
Effect of PNPLA3 rs738409 variant (I148 M) on hepatic steatosis, necroinflammation, and fibrosis in Japanese patients with chronic hepatitis C.
Topics: Adult; Aged; Cross-Sectional Studies; Fatty Liver; Female; Genetic Predisposition to Disease; Hepati | 2015 |
Hepatic lipase (LIPC) C-514T gene polymorphism is associated with cardiometabolic parameters and cardiovascular risk factors but not with fatty liver in Mexican population.
Topics: Adult; Aged; Apolipoprotein A-I; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Choleste | 2015 |
Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant.
Topics: Adult; Fatty Liver; Female; Genetic Variation; Genotype; Humans; Intra-Abdominal Fat; Lipase; Lipid | 2015 |
PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C.
Topics: Adult; Cohort Studies; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lip | 2015 |
[Association between patatin-like phospholipase domain-containing protein 3 gene rs738409 polymorphism and non-alcoholic fatty liver disease susceptibility: a meta-analysis].
Topics: Asian People; Case-Control Studies; Disease Susceptibility; Fatty Liver; Genetic Predisposition to D | 2015 |
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.
Topics: 3T3 Cells; Animals; Autophagy; Carrier Proteins; Cell Line; Fatty Acids; Fatty Liver; HSC70 Heat-Sho | 2015 |
Patatin-Like Phospholipase Domain-Containing 3 I148M Variant Is Associated with Liver Steatosis and Fat Distribution in Chronic Hepatitis B.
Topics: Abdominal Fat; Adult; Aged; Anthropometry; Body Mass Index; Chi-Square Distribution; Cohort Studies; | 2015 |
Potential mechanism underlying the PNPLA3(I) (148) (M) -Hepatic steatosis connection.
Topics: Animals; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins | 2016 |
Reply.
Topics: Animals; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins | 2016 |
PNPLA3 genetic variants determine hepatic steatosis in non-obese chronic hepatitis C patients.
Topics: Adult; Asian People; Body Mass Index; Fatty Liver; Female; Genetic Association Studies; Genetic Pred | 2015 |
The fat droplet in hepatocellular ballooning and implications for scoring nonalcoholic steatohepatitis therapeutic response.
Topics: Animals; Carotid Artery Diseases; Fatty Liver; Female; Hedgehog Proteins; Humans; Lipase; Lipoprotei | 2016 |
Clinical Features of Lysosomal Acid Lipase Deficiency.
Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Child; Child, Preschool; Chole | 2015 |
TM6SF2 rs58542926 is not associated with steatosis and fibrosis in large cohort of patients with genotype 1 chronic hepatitis C.
Topics: Adult; Cohort Studies; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Interferons; Interleukins; | 2016 |
Different Clinical Presentations of Hyperlipidemic Acute Pancreatitis: A Retrospective Study.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amylases; Chi-Square Distribution; China; | 2015 |
Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens.
Topics: Aged; Antiviral Agents; Disease Progression; Fatty Liver; Female; Genome-Wide Association Study; Gen | 2015 |
The Genetic Variant I148M in PNPLA3 Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans.
Topics: Aged; Alleles; Fatty Acids; Fatty Liver; Female; Heterozygote; Homozygote; Humans; Lipase; Lipid Met | 2015 |
Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy.
Topics: Animals; CD36 Antigens; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Fatty Acid Binding | 2015 |
The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection.
Topics: Adult; Age Factors; Alleles; Biopsy; Cohort Studies; Coinfection; Cross-Sectional Studies; Disease P | 2015 |
Impact of PNPLA3 variants on liver histology of 168 patients with HIV infection and chronic hepatitis C.
Topics: Adult; Amino Acid Substitution; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; He | 2016 |
Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line; Cells, Cultured; Co | 2016 |
Childhood predictors of adult fatty liver. The Cardiovascular Risk in Young Finns Study.
Topics: Adolescent; Cardiovascular Diseases; Child; Fatty Liver; Finland; Genetic Predisposition to Disease; | 2016 |
Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Diabetes Mellitus; Fatty Liver; Female; H | 2016 |
Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adipocytes; Animals; Diglycerides; Fatty Liver; Hepato | 2016 |
Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and healthy controls. The GEA study.
Topics: Adult; Alanine Transaminase; Calcinosis; Case-Control Studies; Coronary Artery Disease; Diabetes Mel | 2017 |
LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL).
Topics: Animals; Carrier Proteins; Diet, High-Fat; Fasting; Fatty Liver; Forkhead Box Protein O1; Gene Expre | 2016 |
Combined effects of the PNPLA3 rs738409, TM6SF2 rs58542926, and MBOAT7 rs641738 variants on NAFLD severity: a multicenter biopsy-based study.
Topics: Acyltransferases; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Biopsy; Fatty Liver; Female; | 2017 |
Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Suppressing Adipose Triacylglycerol Lipase Expression.
Topics: 3T3-L1 Cells; Adipocytes, White; Adipose Tissue, White; Animals; Cell Size; Diet, High-Fat; Down-Reg | 2016 |
The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients.
Topics: Adult; Alleles; Coinfection; Cross-Sectional Studies; Disease Progression; Elasticity Imaging Techni | 2016 |
Pigment epithelium-derived factor improves TNFα-induced hepatic steatosis in grass carp (Ctenopharyngodon idella).
Topics: Animals; Carps; Cloning, Molecular; Eye Proteins; Fatty Liver; Fish Diseases; Fish Proteins; Gene Ex | 2017 |
[Association of hepatic lipase gene promoter polymorphism -514C/T with nonalcoholic fatty liver disease].
Topics: Adult; Aged; Case-Control Studies; Fatty Liver; Female; Genotype; Humans; Lipase; Liver; Male; Middl | 2008 |
Severe steatohepatitis in a patient with a rare neutral lipid storage disorder due to ABHD5 mutation.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adult; Fatty Liver; Female; Hepatitis; Humans; Lipase; | 2008 |
Down-regulation of transcription factor peroxisome proliferator-activated receptor in programmed hepatic lipid dysregulation and inflammation in intrauterine growth-restricted offspring.
Topics: Animals; C-Reactive Protein; Down-Regulation; Fatty Acid Synthases; Fatty Liver; Female; Fetal Devel | 2008 |
Candida albicans-secreted lipase induces injury and steatosis in immune and parenchymal cells.
Topics: Animals; Candida albicans; Candidiasis; Cells, Cultured; Cytotoxicity, Immunologic; Fatty Liver; Fem | 2008 |
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Topics: Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Lipase; Male; Mem | 2008 |
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Topics: Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Lipase; Male; Mem | 2008 |
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Topics: Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Lipase; Male; Mem | 2008 |
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Topics: Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Lipase; Male; Mem | 2008 |
Increased expression and activity of hepatic lipase in the liver of morbidly obese adult patients in relation to lipid content.
Topics: Adrenocorticotropic Hormone; Biomarkers; Fatty Liver; Female; Gastric Bypass; Humans; Lipase; Male; | 2009 |
Reduced hepatic expression of adipose tissue triglyceride lipase and CGI-58 may contribute to the development of non-alcoholic fatty liver disease in patients with insulin resistance.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adipose Tissue; Biomarkers; Disease Progression; Fatty | 2008 |
A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans.
Topics: Adult; Aged; Body Mass Index; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; Gluc | 2009 |
Inherited susceptibility to non-alcoholic fatty liver disease.
Topics: Fatty Liver; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Membrane Proteins; Obesity | 2009 |
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn | 2009 |
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn | 2009 |
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn | 2009 |
Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.
Topics: Adult; Diabetes Mellitus, Type 2; Fatty Liver; Female; Genotype; Humans; Lipase; Lipids; Liver; Magn | 2009 |
Nonalcoholic fatty liver disease liver fat score and fat equation to predict and quantitate hepatic steatosis: promising but not prime time!
Topics: Fatty Liver; Humans; Lipase; Lipids; Liver; Magnetic Resonance Spectroscopy; Membrane Proteins; Poly | 2009 |
Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.
Topics: Adipose Tissue; Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; C-Reactive Protein; Cytosine; Fa | 2009 |
Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Body Mass Index; Fatty Liver; | 2010 |
Fetal obesity syndrome: maternal nutrition as a cause of nonalcoholic steatohepatitis.
Topics: Animals; Dietary Fats; Fatty Liver; Female; Humans; Lipase; Maternal Nutritional Physiological Pheno | 2009 |
The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status.
Topics: Animals; Base Sequence; Disease Models, Animal; DNA Primers; Fatty Liver; Female; Gene Expression; G | 2010 |
Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Animals, Newborn; Animals, Suckling; Carboxyl | 2010 |
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis.
Topics: Animals; Cell Line; Fatty Liver; Hepatocytes; Humans; Hydrolysis; Lipase; Liver; Membrane Proteins; | 2010 |
Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis.
Topics: Adipose Tissue; Adiposity; Animals; Blood Glucose; Body Weight; Circadian Rhythm; Dietary Fats; Eati | 2010 |
Regulation effects on abnormal glucose and lipid metabolism of TZQ-F, a new kind of Traditional Chinese Medicine.
Topics: alpha-Glucosidases; Animals; Cholesterol; Cholesterol, LDL; Drugs, Chinese Herbal; Fatty Liver; Free | 2010 |
Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.
Topics: Adult; Aged; Fatty Liver; Female; Genotype; Homozygote; Humans; Lipase; Liver Cirrhosis; Male; Membr | 2010 |
Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people.
Topics: Adiponectin; Adult; Aged; Asian People; Case-Control Studies; Chi-Square Distribution; China; Fatty | 2010 |
The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Child; Cohort Studies; Fatty Liver; F | 2010 |
PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.
Topics: Adult; Alleles; Biopsy; Case-Control Studies; Disease Progression; Fatty Liver; Female; Genetic Pred | 2010 |
I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease.
Topics: Adolescent; Child; Fatty Liver; Female; Fibrosis; Humans; Lipase; Male; Membrane Proteins; Polymorph | 2010 |
The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease.
Topics: Adolescent; Adult; Aged; Alleles; Biopsy; Case-Control Studies; Child; Chromosomes, Human, Pair 10; | 2010 |
A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents.
Topics: Adipose Tissue; Adolescent; Cell Size; Child; Fatty Liver; Female; Gene Expression; Gene Frequency; | 2010 |
Emerging genes associated with the progression of nonalcoholic fatty liver disease.
Topics: Alleles; Biopsy; Disease Progression; Fatty Liver; Genetic Predisposition to Disease; Humans; Lipase | 2010 |
PNPLeAse get the fats right: does lipogenesis or lipolysis cause NASH?
Topics: Adipose Tissue; Animals; Disease Models, Animal; Fatty Liver; Humans; Lipase; Lipogenesis; Lipolysis | 2010 |
Specifically PNPLA3-mediated accumulation of liver fat in obese patients with type 2 diabetes.
Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Body Mass Index; Carotid Arteries; Carrier | 2010 |
Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents.
Topics: Adipose Tissue; Adolescent; Adult; Body Mass Index; Child; Cholesterol, HDL; Fatty Liver; Female; Ge | 2010 |
Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease.
Topics: Child; Fatty Liver; Humans; Lipase; Membrane Proteins; Risk | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption.
Topics: Adiposity; Adolescent; Child; Diet Records; Dietary Carbohydrates; Dietary Sucrose; Fatty Liver; Fee | 2010 |
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning.
Topics: Adipose Tissue; Animals; Fatty Acids; Fatty Liver; Lipase; Liver; Male; Mice; Mice, Inbred C57BL; PP | 2011 |
Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Binding Sites; Fatty Liver; Ge | 2011 |
A common variant in the PNPLA3 gene is a risk factor for non-alcoholic fatty liver disease in obese Taiwanese children.
Topics: Adolescent; Alleles; Child; DNA; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; H | 2011 |
Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.
Topics: Adult; Age Factors; Aged; Alanine Transaminase; Alleles; Aspartate Aminotransferases; Body Mass Inde | 2010 |
Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis.
Topics: Adult; Carrier Proteins; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; I | 2011 |
Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atherosclerosis; Black or African American; Cohort Studi | 2011 |
Distinct, alcohol-modulated effects of PNPLA3 genotype on progression of chronic hepatitis C.
Topics: Alcohol Drinking; Fatty Liver; Genotype; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Memb | 2011 |
Patatin-like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C.
Topics: Adult; Alanine Transaminase; Fatty Liver; Female; gamma-Glutamyltransferase; Hepatitis C, Chronic; H | 2011 |
Methodological concerns about a recent meta-analysis of the influence of the I148M variant of patatin-like phospholipase domain containing 3 on the susceptibility and histological severity of nonalcoholic fatty liver disease.
Topics: Fatty Liver; Genetic Predisposition to Disease; Genetic Variation; Humans; Lipase; Membrane Proteins | 2011 |
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis.
Topics: Alanine Transaminase; Animals; Cytoplasm; Disease Models, Animal; Disease Progression; Energy Metabo | 2011 |
Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C.
Topics: Adult; Aged; Antiviral Agents; Belgium; Cross-Sectional Studies; Disease Progression; Fatty Liver; F | 2011 |
Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus.
Topics: Aged; Black or African American; Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Lipase; Liv | 2011 |
APOC3 polymorphisms and non-alcoholic fatty liver disease: resolving some doubts and raising others.
Topics: Apolipoprotein C-III; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Non-alcoholic Fa | 2011 |
First European Young Hepatologist Workshop: topics and advances.
Topics: Carcinoma, Hepatocellular; End Stage Liver Disease; European Union; Fatty Liver; Genetic Markers; Hu | 2011 |
The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population.
Topics: Adult; Analysis of Variance; Biomarkers; Blood Glucose; Case-Control Studies; Chi-Square Distributio | 2011 |
PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Chi-Square Distribu | 2011 |
PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes.
Topics: Aged; Biomarkers; Body Mass Index; Chi-Square Distribution; Cross-Sectional Studies; Diabetes Mellit | 2011 |
The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies.
Topics: Adult; Base Sequence; Case-Control Studies; Cohort Studies; DNA Primers; Family; Fatty Liver; Female | 2012 |
The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver.
Topics: Adolescent; Adult; Apolipoprotein C-III; Base Sequence; Case-Control Studies; Child; DNA Primers; Fa | 2011 |
The metabolically benign and malignant fatty liver.
Topics: Animals; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 1; Fatty Liver; Hepatitis; Humans; | 2011 |
Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease.
Topics: Acyl Coenzyme A; Amino Acid Substitution; Cell Line; Fatty Liver; Humans; Hydrolysis; Isoenzymes; Li | 2011 |
Genetic variant in PNPLA3 is associated with nonalcoholic fatty liver disease in China.
Topics: Adult; China; Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Lip | 2012 |
Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases.
Topics: Animals; Anti-Obesity Agents; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Intake; Fatt | 2011 |
Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans.
Topics: Adult; Aged; Alanine Transaminase; Biomarkers; Biopsy; Fatty Liver; Female; Genotype; Humans; Insuli | 2012 |
Understanding the relationship between PNPLA3, NAFLD and insulin resistance: do ethnic differences bring more questions or more answers?
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Insulin Resistance; Lipase; L | 2011 |
Modulation of the effect of PNPLA3 I148M mutation on steatosis and liver damage by alcohol intake in patients with chronic hepatitis C.
Topics: Fatty Liver; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Membrane Proteins | 2011 |
Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Apolipoprotein C-III; Black or African American; C | 2012 |
3,5-Diiodo-L-thyronine modulates the expression of genes of lipid metabolism in a rat model of fatty liver.
Topics: Acyl-CoA Oxidase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins B; Diiodothyroni | 2012 |
Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease.
Topics: Adult; Age Factors; Alanine Transaminase; Alleles; Analysis of Variance; Apolipoprotein C-III; Aspar | 2012 |
A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease.
Topics: Alleles; Body Mass Index; Case-Control Studies; Fatty Liver; Female; Gene Frequency; Genetic Predisp | 2012 |
Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation.
Topics: Adipocytes; Adipogenesis; Adipose Tissue, White; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-De | 2012 |
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Topics: Animals; Blotting, Western; Cells, Cultured; Cholesterol; Disease Models, Animal; Endoplasmic Reticu | 2012 |
IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease.
Topics: Adult; Cross-Sectional Studies; Fatty Liver; Female; Humans; Interferons; Interleukins; Lipase; Live | 2012 |
APOC3 and PNPLA3 in non-alcoholic fatty liver disease: need to clear the air.
Topics: Apolipoprotein C-III; Fatty Liver; Female; Humans; Lipase; Male; Membrane Proteins; Non-alcoholic Fa | 2012 |
Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adiposity; Adolescent; Anthropometry; Apolipoprotein B | 2012 |
Hepatic lipase activity is increased in non-alcoholic fatty liver disease beyond insulin resistance.
Topics: Atherosclerosis; Cardiovascular Diseases; Fatty Liver; Humans; Insulin Resistance; Lipase; Liver; No | 2012 |
The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection.
Topics: Adult; Aged; Fatty Liver; Female; Genotype; Hepatitis C, Chronic; Humans; Interferons; Interleukins; | 2012 |
PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study.
Topics: Alcohol Drinking; Body Mass Index; Fatty Liver; Female; Gene Frequency; Genetic Predisposition to Di | 2013 |
Genetic predisposition and increasing dietary fructose exposure: the perfect storm for fatty liver disease in Hispanics in the U.S.
Topics: Diet; Dietary Carbohydrates; Fatty Liver; Fructose; Genetic Predisposition to Disease; Hispanic or L | 2012 |
Hepatic fat accumulation is modulated by the interaction between the rs738409 variant in the PNPLA3 gene and the dietary omega6/omega3 PUFA intake.
Topics: Adipose Tissue; Adolescent; Child; Dietary Fats; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty L | 2012 |
Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C.
Topics: Adult; Alleles; Body Mass Index; Confidence Intervals; Fatty Liver; Female; Genotype; Hepatitis C, C | 2012 |
Liver specific inactivation of carboxylesterase 3/triacylglycerol hydrolase decreases blood lipids without causing severe steatosis in mice.
Topics: Animals; Cholesterol, Dietary; Cholesterol, VLDL; Dietary Fats; Fatty Acids; Fatty Liver; Female; Gl | 2012 |
Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis.
Topics: Adult; Biomarkers; Biopsy; Chi-Square Distribution; Disease Progression; Fatty Liver; Female; Gene F | 2012 |
Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese.
Topics: Adult; Case-Control Studies; Chromosomes, Human, Pair 22; Fatty Liver; Female; Genome-Wide Associati | 2012 |
Understanding the role of PNPLA3 genetic variants in patients with chronic hepatitis C infection.
Topics: Fatty Liver; Hepatitis C, Chronic; Humans; Lipase; Membrane Proteins; Polymorphism, Single Nucleotid | 2012 |
Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells.
Topics: Active Transport, Cell Nucleus; AMP-Activated Protein Kinases; Cell Nucleus; Enzyme Activation; Fatt | 2012 |
Ces3/TGH deficiency improves dyslipidemia and reduces atherosclerosis in Ldlr(-/-) mice.
Topics: Animals; Aorta; Apolipoproteins B; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, V | 2012 |
PNPLA3, a genetic marker of progressive liver disease, still hiding its metabolic function?
Topics: Disease Progression; Fatty Liver; Genetic Markers; Humans; Lipase; Membrane Proteins; Non-alcoholic | 2013 |
The I148M PNPLA3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls.
Topics: Adiponectin; Adult; Aged; Alleles; Case-Control Studies; Fatty Liver; Female; Genetic Predisposition | 2012 |
Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation.
Topics: Animals; Blood Glucose; Cells, Cultured; Fatty Liver; Glucose Tolerance Test; Insulin; Lipase; Liver | 2013 |
The interaction of rs738409, obesity, and alcohol: a population-based autopsy study.
Topics: Accidents, Traffic; Adult; Autopsy; Fatty Liver; Fatty Liver, Alcoholic; Female; Genotype; Humans; K | 2012 |
Reply to: "IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients".
Topics: Fatty Liver; Female; Humans; Interleukins; Lipase; Liver; Male; Membrane Proteins; Polymorphism, Sin | 2013 |
IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian North American patients.
Topics: Fatty Liver; Female; Humans; Interleukins; Lipase; Liver; Male; Membrane Proteins; Polymorphism, Sin | 2013 |
PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease.
Topics: Animals; Fatty Liver; Genetic Predisposition to Disease; Humans; Lipase; Lipogenesis; Lipolysis; Liv | 2012 |
Genetic variant I148M in PNPLA3 is associated with the ultrasonography-determined steatosis degree in a Chinese population.
Topics: Adult; Asian People; Fatty Liver; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; | 2012 |
Genetic variants in PNPLA3 and risk of non-alcoholic fatty liver disease in a Han Chinese population.
Topics: Adult; Alleles; Asian People; Case-Control Studies; Fatty Liver; Female; Genetic Predisposition to D | 2012 |
Adipose tissue is inflamed in NAFLD due to obesity but not in NAFLD due to genetic variation in PNPLA3.
Topics: Adiponectin; Adipose Tissue; Adult; Body Composition; Fatty Liver; Female; Gene Expression Regulatio | 2013 |
Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice.
Topics: Animals; Campanulaceae; Dietary Fats; Disease Models, Animal; Fatty Liver; Female; Lipase; Mice; Mic | 2002 |
[Effects of tea polyphennols on hepatic lipase activity in rabbits with fatty liver].
Topics: Animals; Fatty Liver; Flavonoids; Lipase; Lipids; Liver; Male; Malondialdehyde; Phenols; Polymers; P | 2003 |
Steatohepatitis and unsuspected micronodular cirrhosis in Dorfman-Chanarin syndrome with documented ABHD5 mutation.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Child; Esterases; Fatty Liver; Female; Hepatitis; Huma | 2004 |
Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles.
Topics: Animals; Apolipoproteins C; Diet; Fatty Acids, Essential; Fatty Liver; Gene Expression Profiling; Li | 2005 |
Therapeutic effect of osthole on hyperlipidemic fatty liver in rats.
Topics: Animals; Antioxidants; Cnidium; Coumarins; Fatty Liver; Fenofibrate; Hyperlipidemias; Hypolipidemic | 2007 |
Orlistat reverse fatty infiltration and improves hepatic fibrosis in obese patients with nonalcoholic steatohepatitis (NASH).
Topics: Adult; Biopsy; Body Mass Index; Enzyme Inhibitors; Fatty Liver; Female; Follow-Up Studies; Humans; L | 2007 |
CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.
Topics: Acute-Phase Reaction; Animals; Body Weight; CCAAT-Enhancer-Binding Protein-beta; Choline Deficiency; | 2007 |
Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL).
Topics: Animals; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cells, Cultured; Eye Proteins; Fatty Liver; | 2008 |
Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Apolipoproteins B; Carboxylic Ester Hydrolases; Cell | 2008 |
[Animal experimental studies on the pathogenesis of fatty liver following chronic alcohol administration].
Topics: Alcoholism; Animals; Catecholamines; Ethanol; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; | 1966 |
Ultracytochemical observations on intracytoplasmic lipids by enzymic digestive methods: histochemical trials.
Topics: Animals; Cytoplasm; Erythrocyte Membrane; Ethionine; Fatty Liver; Female; Guinea Pigs; Histocytochem | 1983 |
Hepatic triglyceride lipase activity in plasma of patients with fatty liver, after treatment with heparin.
Topics: Adult; Fatty Liver; Female; Heparin; Humans; Lipase; Male; Middle Aged | 1983 |
Lysosomal changes in fatty liver induced in rats by high protein pyridoxine-deficient diet.
Topics: Acid Phosphatase; Animals; Dietary Proteins; Fatty Liver; Lipase; Lipid Metabolism; Lysosomes; Male; | 1982 |
Dideoxyinosine-induced pancreatitis in human immunodeficiency virus-infected children.
Topics: Amylases; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Fatty Liver; Female; HIV Infections; | 1997 |
The fatty liver dystrophy mutant mouse: microvesicular steatosis associated with altered expression levels of peroxisome proliferator-regulated proteins.
Topics: Animals; Animals, Newborn; Autonomic Nervous System Diseases; Cells, Cultured; Fatty Liver; Genotype | 1998 |
[Wolman's disease: a case with malabsorption and 2 cases with virus- negative fatty liver cirrhosis].
Topics: Biopsy; Calcinosis; Child, Preschool; Cholesterol; Chromosomes, Human, Pair 10; Fatty Liver; Gene De | 2000 |
Hepatic triglyceride lipases--effect of clofibrate and halofenate.
Topics: Animals; Clofibrate; Fatty Acids, Nonesterified; Fatty Liver; Glycolates; Halofenate; Hydrogen-Ion C | 1976 |
[Histochemical investigations on liver and kidney of the rat after intoxication with organophosphates (author's transl)].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cytochrome Reductases; Electron Transport Complex I | 1975 |
[Proceedings: Fat tolerance and postheparin lipases in patients with liver diseases].
Topics: Dietary Fats; Fatty Liver; Heparin; Hepatitis; Humans; Lipase; Liver Cirrhosis; Liver Diseases; Mono | 1975 |
Partial deficiency of acid lipase with storage of triglycerides and cholesterol esters in liver. Genetic variant of Wolman's disease?
Topics: Child; Cholesterol; Cholesterol Esters; Chromatography, Thin Layer; Fatty Liver; Humans; Lipase; Lip | 1976 |
Enzyme histochemical and ultrastructural approach in orotic acid-induced fatty liver and their recovery process in Wistar rats.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Cytoplasm; Endoplasmic Reticulum; Fatty Live | 1988 |
The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities.
Topics: Adipose Tissue; Aging; Animals; Animals, Suckling; Apolipoprotein C-II; Apolipoproteins A; Apolipopr | 1989 |
Ultrastructural and enzyme histochemical studies in orotic acid-induced fatty liver.
Topics: Animals; Esterases; Fatty Liver; Histocytochemistry; Lipase; Liver; Male; Microscopy, Electron; Orot | 1986 |
Specific identification of free and esterified fatty acids in tissue sections.
Topics: Adipose Tissue; Animals; Dioxins; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Histocytoche | 1970 |
[Appearance of zonality in the liver (histochemical study)].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Choline Deficiency; Electron Transport Complex IV; | 1969 |
[Clinical significance of laboratory indicators in patients with chronic liver diseases].
Topics: Alanine Transaminase; Alkaline Phosphatase; Amylases; Aspartate Aminotransferases; Bilirubin; Choles | 1974 |
Sarcoidosis of the pancreas.
Topics: Animals; Diet Therapy; Fatty Liver; Fibroblasts; Granuloma; Humans; Lipase; Liver; Liver Diseases; L | 1972 |
Encephalopathy and fatty degeneration of the viscera: a clinicopathologic analysis of 40 cases.
Topics: Adipose Tissue; Adolescent; Adrenal Glands; Autopsy; Blood Glucose; Brain Diseases; Carbon Dioxide; | 1971 |
Acid lipase in fatty liver in rats.
Topics: Acid Phosphatase; Animals; Choline Deficiency; Chromatography, Thin Layer; Fatty Liver; Hydrogen-Ion | 1971 |