1-anilino-8-naphthalenesulfonate has been researched along with Liver Neoplasms in 118 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Single nucleotide polymorphisms (SNPs) near the epidermal growth factor (EGF) (rs4444903), IL28B (rs12979860), and PNPLA3 (rs738409) loci are associated with treatment response, fibrosis, and hepatocellular carcinoma in non-transplant hepatitis C, but allograft population data are limited." | 3.83 | Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study. ( Chung, RT; Corey, KE; Curry, MP; Fuchs, BC; Gao, T; Gogela, NA; Gordon, FD; Johnson, KB; King, LY; Kothari, D; Lee, JH; Lin, MV; Misdraji, J; Mueller, JL; Nephew, LD; Simpson, MA; Tanabe, KK; Wei, L; Zheng, H, 2016) |
| "We have studied the effects of triiodothyronine (T3) on the production of hepatic triacylglycerol lipase (HTGL) in the human hepatocellular carcinoma cell line, HepG2, by measuring its activity and mRNA levels." | 3.68 | Stimulation of the activity and mRNA level of hepatic triacylglycerol lipase by triiodothyronine in HepG2 cells. ( Funahashi, T; Kubo, M; Matsuzawa, Y; Menju, M; Nozaki, S; Shimomura, I, 1992) |
| "A significantly higher incidence of hepatocellular carcinoma in PNPLA3 148M allele carriers was found in obese individuals in the control group (log-rank P-value = 0." | 2.77 | PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals. ( Adiels, M; Baroni, MG; Borén, J; Burza, MA; Carlsson, LM; Ginanni Corradini, S; Jacobson, P; Maglio, C; Mancina, RM; Montalcini, T; Pirazzi, C; Romeo, S; Sjöholm, K; Sjöström, L; Svensson, PA, 2012) |
| "Nonalcoholic fatty liver disease (NAFLD) affects around a quarter of the global population, paralleling worldwide increases in obesity and metabolic syndrome." | 2.66 | Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology. ( Eslam, M; George, J, 2020) |
| "Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC)." | 2.66 | Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma. ( Goto, T; Hirotsu, Y; Kanda, T; Masuzaki, R; Moriyama, M; Omata, M, 2020) |
| "In some patients with NAFLD, isolated steatosis can progress to advanced stages with non-alcoholic steatohepatitis (NASH) and fibrosis, increasing the risk of cirrhosis and hepatocellular carcinoma." | 2.61 | Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies. ( Cusi, K; Häring, HU; Stefan, N, 2019) |
| "Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and its detection in the general population has reached a global scale." | 2.58 | Clinical-morphological parallels of the PNPLA3 gene polymorphism in patients with nonalcoholic fatty liver disease. ( Baykova, IE; Kislyakov, VA; Nikitin, IG; Tikhomirova, AS, 2018) |
| "Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the United States and represents an increasingly important etiology of hepatocellular carcinoma (HCC) with annual cumulative incidence rates ranging from 2% to 12% in cohorts of NAFLD cirrhosis." | 2.53 | Hepatocellular carcinoma in patients with non-alcoholic fatty liver disease. ( Lim, JK; Nguyen, MH; Wong, CR, 2016) |
| "Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and comprises a liver disease spectrum ranging from steatosis to nonalcoholic steatohepatitis (NASH) with risk of progression to liver cirrhosis and hepatocellular carcinoma (HCC)." | 2.52 | Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH. ( Halilbasic, E; Hofer, H; Kazemi-Shirazi, L; Kienbacher, C; Munda, P; Rechling, C; Trauner, M; Traussnigg, S, 2015) |
| "Nonalcoholic fatty liver disease is correlated albeit imperfectly with obesity and other metabolic diseases such as diabetes, hyperlipidemia, and cardiovascular disease, but exactly how having one of these diseases contributes to the development of other metabolic diseases is only now being elucidated." | 2.52 | Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease. ( Halligan, B; Kahali, B; Speliotes, EK, 2015) |
| "The incidence of hepatocellular carcinoma (HCC) is increasing in Western countries." | 2.50 | Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data. ( Bontempi, G; Burza, MA; Corradini, SG; Deltenre, P; Devière, J; Donati, B; Falleti, E; Franchimont, D; Guyot, E; Hamza, S; Henrion, J; Hillon, P; Mathurin, P; Moreno, C; Nahon, P; Nischalke, HD; Romeo, S; Spengler, U; Toniutto, P; Trépo, E; Valenti, L, 2014) |
| "When liver cancer occurs these processes are impaired and high-density lipoproteins are changed." | 2.44 | Metabolism of high density lipoproteins in liver cancer. ( Jiang, JT; Wu, CP; Xu, N, 2007) |
| "However, the development of hepatocellular carcinoma (HCC), even after the achievement of SVR, continues to be a serious problem." | 1.72 | Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication. ( Furusyo, N; Ikezaki, H; Matsumoto, Y; Murata, M; Ogawa, E; Ohta, A; Yamasaki, S, 2022) |
| "TUSC3 was aberrantly decreased in hepatocellular carcinoma tissues compared to the matched adjacent normal tissues, which resulted in bigger size of tumor (P = 0." | 1.72 | Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis. ( Cai, R; Chen, Q; Deng, R; Hong, C; Lin, J; Lu, X; Wang, P; Wang, X; Xiong, L, 2022) |
| "Patients with NAFLD carrying PNPLA3 rs738409 G>C variant are at higher risk of liver-related events and death." | 1.56 | Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients With Nonalcoholic Fatty Liver Disease. ( Barcellona, MR; Boemi, R; Cammà, C; Celsa, C; Craxì, A; Di Marco, V; Enea, M; Giannetti, A; Grimaudo, S; Marchesini, G; Pennisi, G; Petta, S; Pipitone, RM; Spatola, F, 2020) |
| "NAFLD is multi-factorial in pathogenesis with some genetic predisposition." | 1.56 | The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease. ( Akkız, H; Delik, A; Dinçer, S, 2020) |
| "In Japanese patients with NAFLD, carriage of the HSD17B13 rs6834314 G allele attenuated the effect of the PNPLA3 rs738409 GG genotype on advanced hepatic fibrosis." | 1.56 | Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease. ( Itoh, Y; Kataoka, S; Mori, K; Moriguchi, M; Okanoue, T; Okishio, S; Okuda, K; Seko, Y; Takahashi, A; Tanaka, S; Tochiki, N; Umemura, A; Yamaguchi, K; Yano, K, 2020) |
| "We evaluated the function of ATGL in hepatocellular carcinoma using methyl azazolyl blue and migration assay through overexpression of ATGL in HepG2 cells." | 1.51 | ATGL promotes the proliferation of hepatocellular carcinoma cells via the p-AKT signaling pathway. ( Deng, J; Hong, H; Lin, L; Liu, M; Tang, X; Wang, K; Xia, Y; Yu, X, 2019) |
| "Among 261 patients with liver cirrhosis, rs738409 (GG) genotype was not associated with time-to-HCC development on multivariate Cox regression (P = 0." | 1.48 | Association between PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma in Asian chronic hepatitis C patients: A longitudinal study. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Huang, CM; Hung, CH; Kee, KM; Kuo, YH; Lin, JT; Lin, MT; Lu, SN; Tsai, MC; Tseng, PL; Wang, JH; Wu, CK; Yen, YH, 2018) |
| "Steatosis in hepatocellular carcinoma (HCC) has been recognized for decades and found most commonly in small, well-differentiated HCC." | 1.43 | Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse. ( Chan, AW; Chan, HL; Chan, SL; Chong, CC; Lai, PB; Tin, EK; To, KF; Tong, JH; Wang, L; Wong, GL; Wong, VW; Yu, S; Yu, YH, 2016) |
| "The prevalence of steatohepatitis increased with PNPLA3 CC (14%), CG (20%) and GG (43%) (P < 0." | 1.42 | The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients. ( Boonstra, A; Brouwer, WP; de Knegt, RJ; de Man, RA; Hansen, BE; Janssen, HL; Pas, SD; ten Kate, FJ; van der Meer, AJ, 2015) |
| "Although most hepatocellular carcinoma (HCC) is related to chronic viral hepatitis or alcoholic liver disease, the incidence of NAFLD-related HCC is increasing." | 1.40 | Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. ( Anstee, QM; Burt, AD; Daly, AK; Day, CP; Dufour, JF; Leathart, JB; Liu, YL; Patman, GL; Piguet, AC; Reeves, HL, 2014) |
| "1." | 1.39 | PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma. ( Bertelli, C; Carnelutti, A; Colombo, M; Donati, B; Dongiovanni, P; Facchetti, F; Fargion, S; Fracanzani, AL; Iavarone, M; Motta, BM; Rametta, R; Sangiovanni, A; Soardo, G; Valenti, L, 2013) |
| "Pancreatic panniculitis is a rare complication occurring in 0." | 1.33 | [Pancreatic panniculitis with neuroendocrine pancreatic carcinoma]. ( Hasenöhrl, K; Meurer, M; Stein, A; Wozel, G, 2006) |
| "Since pancreatic cancer is an aggressive and often incurable malignancy, we investigated if the carboxyl ester lipase gene (CEL) is specifically expressed in pancreatic tissues and its promoter can be used for a specific suicide gene approach." | 1.33 | The expression of the carboxyl ester lipase gene in pancreas and pancreatic adenocarcinomas. ( Aberle, S; Blin, N; Franke, FE; Greschniok, A; Klingel, K; Padberg, W; Reuss, R; Sauter, M, 2006) |
| "15 patients with hepatocellular carcinoma and 8 healthy volunteers." | 1.30 | Circulating human hepatic lipase mRNA in patients with hepatocellular carcinoma and healthy controls. ( Leonhardt, U; Ottleben, M; Ramadori, G; Ritzel, U, 1999) |
| "The culture fluid of Hep G2 human hepatoma cells contains triglyceridase activity resistant to high-salt concentrations." | 1.27 | Human hepatoma (Hep G2) cultures contain salt-resistant triglyceridase ("liver lipase"). ( Jansen, H; Persoon, NL; Sips, HJ, 1986) |
| "In patients with cancers, PHLA was similar to that of controls, but the HTGL activity was decreased and the LPL activity was increased." | 1.27 | Hepatic triglyceride lipase and lipoprotein lipase activities in post-heparin plasma of patients with various cancers. ( Itoh, Y; Masuno, H; Ohta, Y; Okuda, H; Onji, M; Shiosaka, T, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (13.56) | 18.7374 |
| 1990's | 12 (10.17) | 18.2507 |
| 2000's | 13 (11.02) | 29.6817 |
| 2010's | 60 (50.85) | 24.3611 |
| 2020's | 17 (14.41) | 2.80 |
| Authors | Studies |
|---|---|
| Ohta, A | 1 |
| Ogawa, E | 1 |
| Murata, M | 1 |
| Matsumoto, Y | 1 |
| Yamasaki, S | 1 |
| Ikezaki, H | 1 |
| Furusyo, N | 1 |
| Patsenker, E | 1 |
| Thangapandi, VR | 1 |
| Knittelfelder, O | 1 |
| Palladini, A | 1 |
| Hefti, M | 1 |
| Beil-Wagner, J | 1 |
| Rogler, G | 1 |
| Buch, T | 2 |
| Shevchenko, A | 1 |
| Hampe, J | 3 |
| Stickel, F | 5 |
| Kim, HS | 1 |
| Xiao, X | 1 |
| Byun, J | 1 |
| Jun, G | 1 |
| DeSantis, SM | 1 |
| Chen, H | 1 |
| Thrift, AP | 1 |
| El-Serag, HB | 1 |
| Kanwal, F | 1 |
| Amos, CI | 1 |
| Youssef, SS | 1 |
| Youness, RA | 1 |
| Abbas, EAE | 1 |
| Osman, NM | 1 |
| ELFiky, A | 1 |
| El-Kassas, M | 1 |
| Deng, R | 1 |
| Lu, X | 1 |
| Hong, C | 1 |
| Cai, R | 1 |
| Wang, P | 2 |
| Xiong, L | 1 |
| Wang, X | 1 |
| Chen, Q | 1 |
| Lin, J | 1 |
| Nischalke, HD | 8 |
| Schmalz, F | 2 |
| Buch, S | 4 |
| Fischer, J | 3 |
| Möller, C | 2 |
| Matz-Soja, M | 2 |
| Krämer, B | 4 |
| Langhans, B | 3 |
| Klüners, A | 2 |
| Soyka, M | 2 |
| Nattermann, J | 4 |
| Berg, T | 5 |
| Strassburg, CP | 3 |
| Lutz, P | 4 |
| Hatano, M | 1 |
| Akiyama, Y | 1 |
| Shimada, S | 1 |
| Yagi, K | 1 |
| Akahoshi, K | 1 |
| Itoh, M | 1 |
| Tanabe, M | 1 |
| Ogawa, Y | 1 |
| Tanaka, S | 2 |
| Grimaudo, S | 1 |
| Pipitone, RM | 1 |
| Pennisi, G | 1 |
| Celsa, C | 1 |
| Cammà, C | 1 |
| Di Marco, V | 1 |
| Barcellona, MR | 1 |
| Boemi, R | 1 |
| Enea, M | 1 |
| Giannetti, A | 1 |
| Spatola, F | 1 |
| Marchesini, G | 1 |
| Craxì, A | 1 |
| Petta, S | 1 |
| Liu, M | 2 |
| Yu, X | 1 |
| Lin, L | 1 |
| Deng, J | 1 |
| Wang, K | 1 |
| Xia, Y | 1 |
| Tang, X | 1 |
| Hong, H | 1 |
| Reuken, PA | 1 |
| Casper, M | 2 |
| Al-Herwi, E | 1 |
| Stengel, S | 1 |
| Spengler, U | 6 |
| Stallmach, A | 1 |
| Lammert, F | 4 |
| Bruns, T | 1 |
| Senkerikova, R | 1 |
| Frankova, S | 1 |
| Jirsa, M | 1 |
| Kreidlova, M | 1 |
| Merta, D | 1 |
| Neroldova, M | 1 |
| Chmelova, K | 1 |
| Spicak, J | 1 |
| Sperl, J | 1 |
| Bartok, E | 1 |
| Frizler, R | 1 |
| Datz, C | 1 |
| Hartmann, G | 1 |
| Eslam, M | 1 |
| George, J | 1 |
| Kanda, T | 1 |
| Goto, T | 1 |
| Hirotsu, Y | 1 |
| Masuzaki, R | 1 |
| Moriyama, M | 1 |
| Omata, M | 1 |
| Wu, C | 1 |
| Li, Y | 2 |
| Gong, Y | 1 |
| Shen, N | 1 |
| Gellert-Kristensen, H | 1 |
| Richardson, TG | 1 |
| Davey Smith, G | 1 |
| Nordestgaard, BG | 1 |
| Tybjaerg-Hansen, A | 1 |
| Stender, S | 1 |
| Delik, A | 1 |
| Akkız, H | 1 |
| Dinçer, S | 1 |
| Seko, Y | 1 |
| Yamaguchi, K | 1 |
| Tochiki, N | 1 |
| Yano, K | 1 |
| Takahashi, A | 1 |
| Okishio, S | 1 |
| Kataoka, S | 1 |
| Okuda, K | 2 |
| Umemura, A | 1 |
| Moriguchi, M | 1 |
| Mori, K | 1 |
| Okanoue, T | 1 |
| Itoh, Y | 2 |
| Wijarnpreecha, K | 1 |
| Scribani, M | 1 |
| Raymond, P | 1 |
| Harnois, DM | 1 |
| Keaveny, AP | 1 |
| Ahmed, A | 1 |
| Kim, D | 1 |
| Miki, D | 1 |
| Akita, T | 1 |
| Kurisu, A | 1 |
| Kawaoka, T | 1 |
| Nakajima, T | 1 |
| Hige, S | 1 |
| Karino, Y | 1 |
| Toyoda, H | 1 |
| Kumada, T | 1 |
| Tsuge, M | 1 |
| Hiramatsu, A | 1 |
| Imamura, M | 2 |
| Aikata, H | 2 |
| Hayes, CN | 1 |
| Honda, K | 2 |
| Seike, M | 1 |
| Akuta, N | 1 |
| Kobayashi, M | 1 |
| Kumada, H | 1 |
| Tanaka, J | 1 |
| Chayama, K | 1 |
| Akiba, J | 1 |
| Yoshida, T | 1 |
| Sadashima, E | 1 |
| Murata, K | 2 |
| Matsui, T | 1 |
| Yamagishi, SI | 1 |
| Kusano, H | 1 |
| Mihara, Y | 1 |
| Mizuochi, S | 1 |
| Kinjou, Y | 1 |
| Naito, Y | 1 |
| Hisaka, T | 1 |
| Sakai, H | 1 |
| Nakashima, O | 1 |
| Yano, H | 1 |
| Gao, X | 1 |
| Liu, W | 1 |
| Yang, L | 1 |
| Zhang, X | 1 |
| Ma, N | 1 |
| Wang, L | 2 |
| Yan, L | 1 |
| Tang, L | 1 |
| Yang, H | 1 |
| Liu, D | 1 |
| Yen, YH | 1 |
| Tsai, MC | 1 |
| Wu, CK | 1 |
| Chang, KC | 1 |
| Hung, CH | 1 |
| Chiu, KW | 1 |
| Lu, SN | 2 |
| Wang, JH | 1 |
| Chen, CH | 1 |
| Kee, KM | 1 |
| Kuo, YH | 1 |
| Tseng, PL | 1 |
| Lin, MT | 1 |
| Huang, CM | 1 |
| Lin, JT | 1 |
| Hu, TH | 1 |
| Weiss, KH | 2 |
| Gotthardt, D | 1 |
| Rosendahl, J | 1 |
| Marot, A | 1 |
| Elamly, M | 1 |
| McQuillin, A | 1 |
| Zopf, S | 1 |
| Marhenke, S | 1 |
| Kirstein, MM | 1 |
| Vogel, A | 1 |
| Eyer, F | 1 |
| von Felden, J | 1 |
| Wege, H | 1 |
| Schafmayer, C | 1 |
| Braun, F | 1 |
| Deltenre, P | 3 |
| Morgan, MY | 2 |
| Liu, X | 2 |
| Liang, Y | 1 |
| Song, R | 1 |
| Yang, G | 1 |
| Han, J | 1 |
| Lan, Y | 1 |
| Pan, S | 1 |
| Zhu, M | 1 |
| Liu, Y | 1 |
| Wang, Y | 1 |
| Meng, F | 1 |
| Cui, Y | 1 |
| Wang, J | 3 |
| Zhang, B | 1 |
| Song, X | 1 |
| Lu, Z | 1 |
| Zheng, T | 1 |
| Liu, L | 1 |
| Zuo, J | 1 |
| Fang, Y | 1 |
| Wen, J | 1 |
| Deng, F | 1 |
| Zhong, H | 1 |
| Jiang, B | 1 |
| Nie, B | 1 |
| Stefan, N | 2 |
| Häring, HU | 2 |
| Cusi, K | 1 |
| Yang, J | 1 |
| Trépo, E | 4 |
| Nahon, P | 5 |
| Cao, Q | 1 |
| Moreno, C | 4 |
| Letouzé, E | 1 |
| Imbeaud, S | 1 |
| Gustot, T | 2 |
| Deviere, J | 2 |
| Debette, S | 1 |
| Amouyel, P | 1 |
| Bioulac-Sage, P | 1 |
| Calderaro, J | 1 |
| Ganne-Carrié, N | 3 |
| Laurent, A | 1 |
| Blanc, JF | 1 |
| Guyot, E | 4 |
| Sutton, A | 3 |
| Ziol, M | 1 |
| Zucman-Rossi, J | 1 |
| Nault, JC | 1 |
| Di Leo, L | 1 |
| Vegliante, R | 1 |
| Ciccarone, F | 1 |
| Salvatori, I | 1 |
| Scimeca, M | 1 |
| Bonanno, E | 1 |
| Sagnotta, A | 1 |
| Grazi, GL | 1 |
| Aquilano, K | 1 |
| Ciriolo, MR | 1 |
| Li, JF | 1 |
| Zheng, EQ | 1 |
| Xie, M | 1 |
| Raksayot, M | 1 |
| Chuaypen, N | 1 |
| Khlaiphuengsin, A | 2 |
| Pinjaroen, N | 2 |
| Treeprasertsuk, S | 1 |
| Poovorawan, Y | 1 |
| Tanaka, Y | 1 |
| Tangkijvanich, P | 2 |
| Wang, LQ | 1 |
| Guo, WH | 1 |
| Guo, ZW | 1 |
| Qin, P | 1 |
| Zhang, R | 1 |
| Zhu, XM | 1 |
| Liu, DW | 1 |
| Niu, CZ | 1 |
| Zhang, FH | 1 |
| Liu, JJ | 1 |
| Bao, CX | 1 |
| Tikhomirova, AS | 1 |
| Kislyakov, VA | 1 |
| Baykova, IE | 1 |
| Nikitin, IG | 1 |
| Huang, Z | 1 |
| Guo, X | 1 |
| Zhang, G | 1 |
| Liang, L | 1 |
| Nong, B | 1 |
| Hassan, MM | 1 |
| Kaseb, A | 1 |
| Etzel, CJ | 1 |
| El-Serag, H | 1 |
| Spitz, MR | 1 |
| Chang, P | 1 |
| Hale, KS | 1 |
| Rashid, A | 1 |
| Shama, M | 1 |
| Abbruzzese, JL | 1 |
| Loyer, EM | 1 |
| Kaur, H | 1 |
| Hassabo, HM | 1 |
| Vauthey, JN | 1 |
| Wray, CJ | 1 |
| Hassan, BS | 1 |
| Patt, YZ | 1 |
| Hawk, E | 1 |
| Soliman, KM | 1 |
| Li, D | 1 |
| Bontempi, G | 1 |
| Valenti, L | 6 |
| Falleti, E | 4 |
| Hamza, S | 2 |
| Corradini, SG | 3 |
| Burza, MA | 5 |
| Donati, B | 3 |
| Hillon, P | 2 |
| Toniutto, P | 4 |
| Henrion, J | 1 |
| Franchimont, D | 2 |
| Mathurin, P | 1 |
| Romeo, S | 8 |
| Sookoian, S | 2 |
| Pirola, CJ | 2 |
| Motta, BM | 1 |
| Soardo, G | 1 |
| Iavarone, M | 1 |
| Sangiovanni, A | 1 |
| Carnelutti, A | 1 |
| Dongiovanni, P | 3 |
| Rametta, R | 1 |
| Bertelli, C | 1 |
| Facchetti, F | 1 |
| Colombo, M | 1 |
| Fargion, S | 1 |
| Fracanzani, AL | 1 |
| Fares, R | 1 |
| Lombardi, R | 1 |
| Mancina, RM | 2 |
| Ezzikouri, S | 1 |
| Alaoui, R | 1 |
| Tazi, S | 1 |
| Nadir, S | 1 |
| Elmdaghri, N | 1 |
| Pineau, P | 1 |
| Benjelloun, S | 1 |
| Limagne, E | 1 |
| Cottet, V | 1 |
| Cotte, AK | 1 |
| Latruffe, N | 1 |
| Delmas, D | 1 |
| Singal, AG | 1 |
| Manjunath, H | 1 |
| Yopp, AC | 1 |
| Beg, MS | 1 |
| Marrero, JA | 1 |
| Gopal, P | 1 |
| Waljee, AK | 1 |
| Liu, YL | 2 |
| Patman, GL | 1 |
| Leathart, JB | 1 |
| Piguet, AC | 1 |
| Burt, AD | 1 |
| Dufour, JF | 1 |
| Day, CP | 4 |
| Daly, AK | 2 |
| Reeves, HL | 2 |
| Anstee, QM | 3 |
| Min, HK | 1 |
| Cheng, J | 1 |
| Mirshahi, F | 1 |
| Sanyal, AJ | 1 |
| Friedrich, K | 1 |
| Wannhoff, A | 1 |
| Kattner, S | 1 |
| Brune, M | 1 |
| Hov, JR | 1 |
| Antoni, C | 1 |
| Dollinger, M | 1 |
| Neumann-Haefelin, C | 1 |
| Seufferlein, T | 1 |
| Schemmer, P | 1 |
| Schirmacher, P | 1 |
| Stremmel, W | 1 |
| Gotthardt, DN | 1 |
| Brouwer, WP | 1 |
| van der Meer, AJ | 1 |
| Boonstra, A | 1 |
| Pas, SD | 1 |
| de Knegt, RJ | 1 |
| de Man, RA | 1 |
| Hansen, BE | 1 |
| ten Kate, FJ | 1 |
| Janssen, HL | 1 |
| Krawczyk, M | 1 |
| Stokes, CS | 1 |
| Salameh, H | 1 |
| Raff, E | 1 |
| Erwin, A | 1 |
| Seth, D | 1 |
| Leathert, J | 1 |
| Molinaro, A | 2 |
| Ulrich, S | 1 |
| Daly, A | 1 |
| Kuo, YF | 1 |
| Singal, AK | 1 |
| Traussnigg, S | 1 |
| Kienbacher, C | 1 |
| Halilbasic, E | 1 |
| Rechling, C | 1 |
| Kazemi-Shirazi, L | 1 |
| Hofer, H | 1 |
| Munda, P | 1 |
| Trauner, M | 1 |
| Geng, N | 1 |
| Jiang, M | 1 |
| Zhang, D | 1 |
| Xin, Y | 2 |
| Xuan, S | 2 |
| Ueyama, M | 1 |
| Nishida, N | 1 |
| Korenaga, M | 1 |
| Korenaga, K | 1 |
| Kumagai, E | 1 |
| Yanai, H | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Microbiome Reprogramming on Liver Fat Accumulation[NCT03914495] | 57 participants (Actual) | Interventional | 2019-05-21 | Terminated (stopped due to PI carefully considered multiple factors and decided to close study to any further enrollment.) | |||
| Comparative Clinical Study to Evaluate the Possible Beneficial Effect of Empagliflozin Versus Pioglitazone on Non-diabetic Patients With Non-Alcoholic Steatohepatitis[NCT05605158] | Phase 3 | 56 participants (Anticipated) | Interventional | 2022-11-30 | Not yet recruiting | ||
| The Role of the PNPLA3, TM6SF2 and MBOAT7 Genetic Variants in the Response to Silybin-phospholipid Complex, Vitamin D and Vitamin E Based Therapy for Non-alcoholic Fatty Liver Disease Patients[NCT04640324] | 92 participants (Actual) | Interventional | 2017-01-16 | Completed | |||
| Effects of Bariatric Surgery in Swedish Obese Subjects[NCT01479452] | 4,047 participants (Actual) | Interventional | 1987-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for 1-anilino-8-naphthalenesulfonate and Liver Neoplasms
| Article | Year |
|---|---|
Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology.
Topics: 17-Hydroxysteroid Dehydrogenases; Acyltransferases; Adaptor Proteins, Signal Transducing; Carcinoma, | 2020 |
Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Apoptosis; Carcinoma, Hepatocellular; Diet, High-Fat; Dis | 2020 |
PNPLA3 rs738409 is not associated with the risk of hepatocellular carcinoma and persistent infection of hepatitis B virus (HBV) in HBV-related subjects: A case-control study and meta-analysis on Asians.
Topics: Adult; Aged; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; Female; Genetic Predispo | 2020 |
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit | 2019 |
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit | 2019 |
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit | 2019 |
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit | 2019 |
Association between rs738409 polymorphism in patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene and hepatocellular carcinoma susceptibility: Evidence from case-control studies.
Topics: Alleles; Carcinoma, Hepatocellular; Case-Control Studies; Genetic Association Studies; Genetic Predi | 2019 |
Clinical-morphological parallels of the PNPLA3 gene polymorphism in patients with nonalcoholic fatty liver disease.
Topics: Humans; Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Membrane Proteins; Non-alcoholic Fatty Live | 2018 |
Correlation between
Topics: Carcinoma, Hepatocellular; Case-Control Studies; Genetic Predisposition to Disease; Humans; Lipase; | 2019 |
Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data.
Topics: Carcinoma, Hepatocellular; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis, Alcoholic; Liver N | 2014 |
PNPLA3 I148M polymorphism and progressive liver disease.
Topics: Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Disease Progression; Fatty Liver; Fatty Liver, A | 2013 |
The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis.
Topics: Carcinoma, Hepatocellular; Disease Progression; Genetic Predisposition to Disease; Humans; Lipase; L | 2014 |
PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease.
Topics: Carcinoma, Hepatocellular; Central Nervous System Depressants; Chemical and Drug Induced Liver Injur | 2015 |
Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH.
Topics: Anticholesteremic Agents; Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Disease Progre | 2015 |
Significant Association Between Adiponutrin and Hepatocellular Carcinoma Risk.
Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Humans; Lipase; Liver Neoplasms; Membr | 2015 |
Genetics of Alcoholic Liver Disease.
Topics: Alcohol Drinking; Alcoholism; Carcinoma, Hepatocellular; Disease Progression; Ethanol; Fatty Liver, | 2015 |
Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease.
Topics: Adaptor Proteins, Signal Transducing; Carcinoma, Hepatocellular; Genetic Predisposition to Disease; | 2015 |
Hepatocellular carcinoma in patients with non-alcoholic fatty liver disease.
Topics: Adiponectin; Carcinoma, Hepatocellular; Disease Progression; Humans; Immune System; Inflammation; Li | 2016 |
PNPLA3 I148M variant and hepatocellular carcinoma: a common genetic variant for a rare disease.
Topics: Carcinoma, Hepatocellular; Fatty Liver; Genetic Markers; Hepatitis, Chronic; Humans; Lipase; Liver C | 2013 |
Metabolism of high density lipoproteins in liver cancer.
Topics: Cholesterol; Humans; Lipase; Lipoproteins, HDL; Liver; Liver Neoplasms; Protein Kinase C; Receptors, | 2007 |
Laboratory aids to diagnosis--enzymes.
Topics: Acid Phosphatase; Alkaline Phosphatase; Amylases; Aryl Hydrocarbon Hydroxylases; Bone Neoplasms; Cli | 1976 |
1 trial available for 1-anilino-8-naphthalenesulfonate and Liver Neoplasms
| Article | Year |
|---|---|
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.
Topics: Adult; Bariatric Surgery; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genetic Markers; Gen | 2012 |
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.
Topics: Adult; Bariatric Surgery; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genetic Markers; Gen | 2012 |
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.
Topics: Adult; Bariatric Surgery; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genetic Markers; Gen | 2012 |
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.
Topics: Adult; Bariatric Surgery; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genetic Markers; Gen | 2012 |
98 other studies available for 1-anilino-8-naphthalenesulfonate and Liver Neoplasms
| Article | Year |
|---|---|
Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication.
Topics: Acyltransferases; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Genotype; Hepacivirus; Hepa | 2022 |
The PNPLA3 variant I148M reveals protective effects toward hepatocellular carcinoma in mice via restoration of omega-3 polyunsaturated fats.
Topics: Acyltransferases; Alcohol Drinking; Animals; Carcinoma, Hepatocellular; Docosahexaenoic Acids; Fatty | 2022 |
Synergistic Associations of PNPLA3 I148M Variant, Alcohol Intake, and Obesity With Risk of Cirrhosis, Hepatocellular Carcinoma, and Mortality.
Topics: Acyltransferases; Alcohol Drinking; Carcinoma, Hepatocellular; Female; Humans; Lipase; Liver Cirrhos | 2022 |
miR-516a-3P, a potential circulating biomarker in hepatocellular carcinoma, correlated with
Topics: Acyltransferases; Biomarkers; Carcinoma, Hepatocellular; Hepatitis C; Humans; Lipase; Liver Neoplasm | 2022 |
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epi | 2022 |
Genetic Variation of
Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho | 2022 |
Genetic Variation of
Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho | 2022 |
Genetic Variation of
Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho | 2022 |
Genetic Variation of
Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho | 2022 |
Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease-related HCC.
Topics: Animals; Carcinoma, Hepatocellular; Cell Cycle Proteins; Humans; Jumonji Domain-Containing Histone D | 2023 |
Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients With Nonalcoholic Fatty Liver Disease.
Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Neopla | 2020 |
ATGL promotes the proliferation of hepatocellular carcinoma cells via the p-AKT signaling pathway.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Hep G2 Cells; Human | 2019 |
The ATG16L1 gene variant rs2241880 (p.T300A) is associated with susceptibility to HCC in patients with cirrhosis.
Topics: Aged; Autophagy-Related Proteins; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; F | 2019 |
PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.
Topics: Alleles; Carcinoma, Hepatocellular; Case-Control Studies; Cross-Sectional Studies; Female; Genetic P | 2019 |
The PNPLA3 I148M variant promotes lipid-induced hepatocyte secretion of CXC chemokines establishing a tumorigenic milieu.
Topics: Carcinoma, Hepatocellular; Chemokine CXCL1; Chemokine CXCL5; Chemokines, CXC; Genetic Predisposition | 2019 |
Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population.
Topics: 17-Hydroxysteroid Dehydrogenases; Alanine Transaminase; Carcinoma, Hepatocellular; Denmark; Female; | 2020 |
The effect of PNPLA3 polymorphism as gain in function mutation in the pathogenesis of non-alcoholic fatty liver disease.
Topics: Carcinoma, Hepatocellular; Deception; Humans; Lipase; Liver Neoplasms; Membrane Proteins; Metabolic | 2020 |
Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease.
Topics: Humans; Japan; Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Membrane Proteins; Non-alcoholic Fat | 2020 |
PNPLA3 Gene Polymorphism and Liver- and Extrahepatic Cancer-Related Mortality in the United States.
Topics: Carcinoma, Hepatocellular; Female; Genetic Predisposition to Disease; Humans; Lipase; Liver; Liver N | 2021 |
PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Female; Follow-Up Studies; Hepatitis C, | 2020 |
The Expression of PEDF and its Putative Receptors in Hepatocellular Carcinoma and Background Liver Tissue.
Topics: Carcinoma, Hepatocellular; Eye Proteins; Female; Humans; Immunohistochemistry; Lipase; Liver; Liver | 2021 |
Association between PNPLA3 gene polymorphisms and risk of hepatitis B virus-related hepatocellular carcinoma in Han population in China:a case-control study.
Topics: Adult; Aged; Asian People; Carcinoma, Hepatocellular; Case-Control Studies; China; Female; Genetic P | 2017 |
Association between PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma in Asian chronic hepatitis C patients: A longitudinal study.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Cross-Sectional Studies; Female; Genetic Predisposition to D | 2018 |
Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis.
Topics: Acyltransferases; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Disease Progression; Europe | 2018 |
Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Diglycerides; Fatty Acids, | 2018 |
Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells.
Topics: AC133 Antigen; Down-Regulation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatoblastoma | 2018 |
PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases.
Topics: Carcinoma, Hepatocellular; Cohort Studies; Female; Genetic Predisposition to Disease; Genetic Variat | 2019 |
Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53.
Topics: Acetylation; Animals; Carcinoma, Hepatocellular; E1A-Associated p300 Protein; Gene Expression Regula | 2019 |
Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma.
Topics: Acyltransferases; Aged; Alleles; Carcinoma, Hepatocellular; Case-Control Studies; Chondroitin Sulfat | 2019 |
[Effects of PNPLA3, TM6SF2 gene polymorphisms and its interactions with smoking and alcohol drinking on hepatitis B virus-associated hepatocellular carcinoma].
Topics: Alcohol Drinking; Carcinoma, Hepatocellular; Case-Control Studies; Epistasis, Genetic; Gene-Environm | 2018 |
The -250G/A and -514C/T Polymorphisms in Hepatic Lipase Gene Promoter Confers an Increased Risk of Hepatocellular Carcinoma in a Chinese Population.
Topics: Adult; Aged; Asian People; Carcinoma, Hepatocellular; Cohort Studies; Female; Genetic Predisposition | 2018 |
Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction.
Topics: Adult; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Female; Genotype; Humans; | 2013 |
PNPLA3, the history of an orphan gene of the potato tuber protein family that found an organ: the liver.
Topics: Carcinoma, Hepatocellular; Humans; Lipase; Liver Neoplasms; Membrane Proteins | 2014 |
PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Case-Control Studies; Demography; Fatty Liver; Female; Follow-Up St | 2013 |
The adiponutrin I148M variant is a risk factor for HCV-associated liver cancer in North-African patients.
Topics: Aged; Carcinoma, Hepatocellular; Female; Gene Frequency; Genotype; Hepadnaviridae; Humans; Lipase; L | 2014 |
Reply: To PMID 24114809.
Topics: Carcinoma, Hepatocellular; Humans; Lipase; Liver Neoplasms; Membrane Proteins | 2014 |
Potential role of oxidative DNA damage in the impact of PNPLA3 variant (rs 738409 C>G) in hepatocellular carcinoma risk.
Topics: Carcinoma, Hepatocellular; Humans; Lipase; Liver Neoplasms; Membrane Proteins | 2014 |
Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; Disease Progression; F | 2014 |
Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells.
Topics: Biomarkers; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatography, Liquid; Gas Chromatography- | 2014 |
PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
Topics: Alleles; Carcinoma, Hepatocellular; Cohort Studies; Genetic Association Studies; Genotype; Humans; L | 2014 |
The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients.
Topics: Body Weight; Carcinoma, Hepatocellular; Fatty Liver; Female; Hepatitis B, Chronic; Humans; Iron; Lip | 2015 |
HCC and liver disease risks in homozygous PNPLA3 p.I148M carriers approach monogenic inheritance.
Topics: Carcinoma, Hepatocellular; Female; Humans; Lipase; Liver Neoplasms; Male; Membrane Proteins; Non-alc | 2015 |
Reply to: HCC and liver disease risk in homozygous PNPLA3 p.I148M carriers approach monogenic inheritance.
Topics: Carcinoma, Hepatocellular; Female; Humans; Lipase; Liver Neoplasms; Male; Membrane Proteins; Non-alc | 2015 |
[I148M polymorphism of PNPLA3 gene affects cell cycle of hepatoma carcinoma cell Huh-7].
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cyclin D1; Flow Cytometry; Humans; Lipase; | 2015 |
The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Co-Repressor Proteins; Diabetes Mellitus, Type 2 | 2016 |
[Polymorphisms in the PNPLA3 gene are associated with hepatocellular carcinoma].
Topics: Carcinoma, Hepatocellular; Humans; Lipase; Liver Neoplasms; Membrane Proteins; Polymorphism, Genetic | 2015 |
PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis.
Topics: Carcinoma, Hepatocellular; Female; Homozygote; Humans; Lipase; Liver Cirrhosis, Alcoholic; Liver Neo | 2016 |
Association of PNPLA3 Polymorphism with Hepatocellular Carcinoma Development and Prognosis in Viral and Non-Viral Chronic Liver Diseases.
Topics: Aged; Carcinoma, Hepatocellular; Case-Control Studies; Disease Progression; Fatty Liver, Alcoholic; | 2015 |
Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study.
Topics: Adult; Allografts; Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Disease Progression; | 2016 |
Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Diabetes Mellitus; Fatty Liver; Female; H | 2016 |
The association of variants in PNPLA3 and GRP78 and the risk of developing hepatocellular carcinoma in an Italian population.
Topics: Aged; Alleles; Carcinoma, Hepatocellular; Cohort Studies; Endoplasmic Reticulum Chaperone BiP; Femal | 2016 |
Enhanced cellular uptake of remnant high-density lipoprotein particles: a mechanism for high-density lipoprotein lowering in insulin resistance and hypertriglyceridemia.
Topics: Anticoagulants; Apolipoprotein A-I; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Choleste | 2008 |
Glucose increases hepatic lipase expression in HepG2 liver cells through upregulation of upstream stimulatory factors 1 and 2.
Topics: Animals; Cell Line; Cell Line, Tumor; DNA Primers; Female; Gene Expression Regulation, Enzymologic; | 2008 |
Upstream Stimulatory Factors 1 and 2 activate the human hepatic lipase promoter via E-box dependent and independent mechanisms.
Topics: Animals; Carcinoma, Hepatocellular; Chlorocebus aethiops; Chromatin Immunoprecipitation; COS Cells; | 2009 |
Patatin-like phospholipase domain containing 3 sequence variant and hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Female; Hepatitis C; Humans; Lipase; Liver Cirrhosis; Liver Neoplasms; Ma | 2011 |
First European Young Hepatologist Workshop: topics and advances.
Topics: Carcinoma, Hepatocellular; End Stage Liver Disease; European Union; Fatty Liver; Genetic Markers; Hu | 2011 |
PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Chi-Square Distribu | 2011 |
The metabolically benign and malignant fatty liver.
Topics: Animals; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 1; Fatty Liver; Hepatitis; Humans; | 2011 |
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Female; Genetic Pre | 2011 |
PNPLA3 (rs738409 C>G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis.
Topics: Adult; Aged; Belgium; Carcinoma, Hepatocellular; Comorbidity; Female; France; Genetic Predisposition | 2012 |
Transarterial chemoembolization of liver metastases as symptomatic therapy of lipase hypersecretion syndrome.
Topics: Aged; Carcinoma, Acinar Cell; Chemoembolization, Therapeutic; Humans; Lipase; Liver Neoplasms; Male; | 2012 |
The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis.
Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Carcinoma, Hepatocellular; Female; Follow-Up Studie | 2013 |
PNPLA3 Ile148Met variant and hepatocellular carcinoma: a matter of fat.
Topics: Carcinoma, Hepatocellular; Female; Humans; Lipase; Liver Neoplasms; Male; Membrane Proteins; Obesity | 2012 |
Immunogenic cell death biomarkers HMGB1, RAGE, and DNAse indicate response to radioembolization therapy and prognosis in colorectal cancer patients.
Topics: Adult; Aged; Alkaline Phosphatase; Amylases; Analysis of Variance; Antigens, Neoplasm; Apoptosis; Bi | 2013 |
PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis.
Topics: Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Incide | 2013 |
Multiple loss of heterozygosity without K-ras mutation identified by molecular analysis on fine-needle aspiration cytology specimen of acinar cell carcinoma of pancreas.
Topics: Adenocarcinoma; Aged; Biopsy, Needle; Carcinoma, Acinar Cell; Diagnosis, Differential; Genes, ras; H | 2002 |
[Morphology and distribution of lipase in various conditions of hepatic pathology].
Topics: Humans; Lipase; Liver Neoplasms | 1954 |
SERUM TRIBUTYRINASE LEVELS IN HEALTH AND DISEASE.
Topics: Anemia; Anemia, Macrocytic; Clinical Enzyme Tests; Diabetes Mellitus; Dyspepsia; Female; Glomerulone | 1963 |
Antitumour activity of fatty acid maltotriose esters obtained by enzymatic synthesis.
Topics: Acetylation; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Esters; Fatty Acids; HeLa Cells | 2005 |
Sterol-regulatory-element binding protein inhibits upstream stimulatory factor-stimulated hepatic lipase gene expression.
Topics: Anticholesteremic Agents; Atorvastatin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; DN | 2005 |
[Pancreatic panniculitis with neuroendocrine pancreatic carcinoma].
Topics: Aged; Biopsy; Humans; Lipase; Liver Neoplasms; Male; Necrosis; Neuroendocrine Tumors; Pancreatic Neo | 2006 |
The expression of the carboxyl ester lipase gene in pancreas and pancreatic adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Acinar Cell; Carcinoma, Panc | 2006 |
CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Animals; Carcinoma, Hepatocellular; Cell Line; CHO Cel | 2007 |
A case with mature B-cell acute lymphoblastic leukemia and pancreatic involvement at the time of diagnosis.
Topics: Acute Disease; Amylases; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Diagnosis | 2008 |
Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan.
Topics: Adult; Carbolines; Carcinoma, Hepatocellular; Diabetes Mellitus; Female; Follow-Up Studies; Hepatiti | 2008 |
Pancreatic lipase is a useful phenotypic marker of intrahepatic large and septal bile ducts, peribiliary glands, and their malignant counterparts.
Topics: Adenoma, Bile Duct; Bile Ducts, Intrahepatic; Biomarkers; Biomarkers, Tumor; Cholelithiasis; Humans; | 1993 |
Chronic increased serum lipase without evidence of pancreatitis: tumor-derived lipase?
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Electrophoresis, | 1996 |
Hepatic lipase secretion in human hepatoblastoma cell line Hep G2 is not related to cellular cholesterol homeostasis.
Topics: Cholesterol; Hepatoblastoma; Homeostasis; Humans; Lipase; Liver; Liver Neoplasms; Receptors, LDL; Tu | 1995 |
Structure and liver-specific expression of hepatic lipase.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Gene Express | 1996 |
Regulation of hepatic lipase secretion from Hep G2 cells by ACTH and corticosteroids.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Dexamethasone; Hepatoblastoma; Hu | 1997 |
Regulation of hepatic lipase expression in HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cholesterol; Gene Expression Regulation, Enzymologic; Gene Expression Reg | 1997 |
Increased serum lipase with associated normoamylasemia in cancer patients.
Topics: Adenocarcinoma; alpha-Amylases; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Colorectal Neoplas | 1998 |
Circulating human hepatic lipase mRNA in patients with hepatocellular carcinoma and healthy controls.
Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Female; Humans; Lipase; Liver Ne | 1999 |
Glucose regulates the transcription of human genes relevant to HDL metabolism: responsive elements for peroxisome proliferator-activated receptor are involved in the regulation of phospholipid transfer protein.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; ATP-Binding Cassette Transporters; Carcinoma, Hepatocellula | 2001 |
Lysis of tumor cells by antibody and complement. VI. Enhanced killing of enzyme-pretreated tumor cells.
Topics: Animals; Antibodies, Neoplasm; Bromelains; Carcinoma, Hepatocellular; Cytotoxicity Tests, Immunologi | 1976 |
Association of islet cell carcinoma of the pancreas with subcutaneous fat necrosis.
Topics: Acid Phosphatase; Adenoma, Islet Cell; Alkaline Phosphatase; Fat Necrosis; Humans; Leucyl Aminopepti | 1979 |
[Functioning carcinoma of the exocrinic pancreas. Case report and review of the literature (author's transl)].
Topics: Autopsy; Erythema Nodosum; Humans; Lipase; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; | 1977 |
Lipoprotein assembly. Apolipoprotein B size determines lipoprotein core circumference.
Topics: Apolipoproteins B; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Humans; Lipase; L | 1992 |
Stimulation of the activity and mRNA level of hepatic triacylglycerol lipase by triiodothyronine in HepG2 cells.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Heparin; | 1992 |
Regulation of hepatic lipase expression by an intermediate of the cellular cholesterol biosynthetic pathway.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cholesterol; Gene Expression Regulation, Enzymologic; | 1991 |
Differential regulation of hepatic triglyceride lipase and 3-hydroxy-3-methylglutaryl-CoA reductase gene expression in a human hepatoma cell line, HepG2.
Topics: Carcinoma, Hepatocellular; Cell Line; Cholesterol; Gene Expression Regulation; Hydroxymethylglutaryl | 1990 |
Human hepatoma (Hep G2) cultures contain salt-resistant triglyceridase ("liver lipase").
Topics: Animals; Antibodies; Carcinoma, Hepatocellular; Cell Line; Chromatography, Affinity; Epitopes; Human | 1986 |
Human hepatoma (HepG2) cells secrete a single 65 K dalton triglyceride lipase immunologically identical to postheparin plasma hepatic lipase.
Topics: Antibodies, Monoclonal; Blotting, Western; Carcinoma, Hepatocellular; Epitopes; Humans; Immunoblotti | 1989 |
Heparin induces the expression of hepatic triglyceride lipase in a human hepatoma (HepG2) cell line.
Topics: Carcinoma, Hepatocellular; Cell Line; Cell-Free System; Culture Media; Enzyme Induction; Heparin; Hu | 1989 |
Glycosaminoglycans regulate the expression of human hepatic triglyceride lipase in HepG2 cells.
Topics: Amino Acid Sequence; Blotting, Western; Carcinoma, Hepatocellular; Gene Expression Regulation, Enzym | 1988 |
Hepatic triglyceride lipase and lipoprotein lipase activities in post-heparin plasma of patients with various cancers.
Topics: Aged; Carcinoma, Hepatocellular; Cholesterol; Female; Humans; Lipase; Lipoprotein Lipase; Lipoprotei | 1985 |
A histochemical study of few enzymes in the neoplastic liver of Corvus spledens (Vieillot).
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Bird Diseases; Esterases; Lipase; Liver Neoplasms; | 1973 |
[On the enzymo-histologic characteristic of cancers of the liver. I. Studies of the activity of alkaline phosphatase, acid phosphatase, lipase and nonspecific esterase].
Topics: Esterases; Humans; In Vitro Techniques; Lipase; Liver Neoplasms; Phosphoric Monoester Hydrolases | 1965 |
Microsomal synthesis of the ether analogs of triacylglycerols. Acyl CoA:alkylacylglycerol and acyl CoA:alk-i-enylacylglycerol acyltransferases in tumors and liver.
Topics: Acyltransferases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Chromatography, Thin Lay | 1974 |
Lipase-secreting acinar cell carcinoma of the pancreas with polyarthropathy. A light and electron microscopic, histochemical, and biochemical study.
Topics: Alcoholism; Ankle Joint; Autopsy; Biopsy; Carcinoma; Elbow Joint; Histocytochemistry; Humans; Joint | 1974 |
[Histochemical studies of esterase in tumor cells. 2. On esterase and lipase reactions and lipids in experimental liver tumor].
Topics: Animals; Esterases; Lipase; Lipid Metabolism; Liver Neoplasms; Neoplasms, Experimental; p-Dimethylam | 1966 |