1-anilino-8-naphthalenesulfonate has been researched along with Cirrhosis in 65 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Impact of rofecoxib on progressing of pancreatic fibrous changes in the rats in experimental chronic pancreatitis, caused by L-arginine, was studied up." | 7.79 | [New approach for treatment of chronic pancreatitis, caused by L-arginine, in rats]. ( Berehova, TV; Falalieieva, TM; Petrushenko, VV; Sukhodolia, SA, 2013) |
| "Thirty rats were divided into three equal groups: group 1, sham laparotomy; group 2, severe hyperstimulation and obstruction pancreatitis (SHOP) with no treatment; group 3, SHOP with halofuginone treatment group." | 7.74 | The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis. ( Ayan, F; Aydogan, F; Carkman, S; Durak, H; Erzin, Y; Gonenc, M; Karatas, A; Paksoy, M; Uzun, H, 2008) |
| "The results of the present study suggest that camostat greatly inhibits pancreatic inflammation and prevents and reverses fibrosis and atrophy of the pancreas in the genetically obese and CCK-1 receptor-deficient OLETF rats." | 7.73 | Preventive and therapeutic effects of the protease inhibitor camostat on pancreatic fibrosis and atrophy in CCK-1 receptor-deficient rats. ( Jia, D; Otsuki, M; Taguchi, M, 2005) |
| "Chronic pancreatitis is considered a common gastrointestinal disorder, with significant morbidity and mortality." | 5.62 | Fraxetin prevented sodium fluoride-induced chronic pancreatitis in rats: Role of anti-inflammatory, antioxidant, antifibrotic and anti-apoptotic activities. ( Ahmed, N; Balaha, M; Geddawy, A; Kandeel, S, 2021) |
| "Two murine models were used to determine whether CCK receptor blockade with proglumide could prevent and reverse histologic and biochemical features of chronic pancreatitis: the 6-week repetitive chronic cerulein injection model and the modified 75% choline-deficient ethionine (CDE) diet." | 3.96 | Cholecystokinin Receptor Antagonist Therapy Decreases Inflammation and Fibrosis in Chronic Pancreatitis. ( Cao, H; Ciofoaia, V; Kallakury, B; Nadella, S; Smith, JP; Tucker, RD, 2020) |
| "05) with serum levels of alanine aminotransferase (ALT), asparate aminotransferase (AST), glucose, fibrinogen, and insulin-dependent diabetes mellitus, homeostasis model assessment-insulin resistance, and presence of NASH." | 3.79 | Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity. ( Charlton, MR; Gawrieh, S; Guichelaar, MM; Krishnan, A; Malinchoc, M; Olivier, M; Sanderson, S; Sarr, M; Swain, JM; Viker, K; Watt, KD, 2013) |
| "Impact of rofecoxib on progressing of pancreatic fibrous changes in the rats in experimental chronic pancreatitis, caused by L-arginine, was studied up." | 3.79 | [New approach for treatment of chronic pancreatitis, caused by L-arginine, in rats]. ( Berehova, TV; Falalieieva, TM; Petrushenko, VV; Sukhodolia, SA, 2013) |
| "Thirty rats were divided into three equal groups: group 1, sham laparotomy; group 2, severe hyperstimulation and obstruction pancreatitis (SHOP) with no treatment; group 3, SHOP with halofuginone treatment group." | 3.74 | The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis. ( Ayan, F; Aydogan, F; Carkman, S; Durak, H; Erzin, Y; Gonenc, M; Karatas, A; Paksoy, M; Uzun, H, 2008) |
| "The results of the present study suggest that camostat greatly inhibits pancreatic inflammation and prevents and reverses fibrosis and atrophy of the pancreas in the genetically obese and CCK-1 receptor-deficient OLETF rats." | 3.73 | Preventive and therapeutic effects of the protease inhibitor camostat on pancreatic fibrosis and atrophy in CCK-1 receptor-deficient rats. ( Jia, D; Otsuki, M; Taguchi, M, 2005) |
| "To cast light on the mechanisms underlying development of spontaneous pancreatitis lesions, tissues from WBN/Kob rats at various ages were histopathologically and immunohistochemically investigated with special reference to the existence of the lipid peroxidation products 4-hydroxy-2-nonenal (HNE), 4-hydroxy-2-hexenal (HHE), and malondialdehyde (MDA)." | 3.71 | Involvement of lipid peroxidation in spontaneous pancreatitis in WBN/Kob rats. ( Furukawa, F; Hirose, M; Kasahara, K; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY; Uchida, K, 2001) |
| "Di-n-butyltin dichloride (DBTC) induced thymus atrophy, bile duct lesions, pancreatitis, and liver lesions in rats." | 3.71 | Repeated administration of a mild acute toxic dose of di-n-butyltin dichloride at intervals of 3 weeks induces severe lesions in pancreas and liver of rats. ( Hennighausen, G; Kröning, G; Merkord, J; Weber, H, 2001) |
| " Pathohistological changes in pancreas, bile duct and liver as well as pathobiochemical parameters of pancreatitis (amylase and lipase activity), liver lesions (alkaline phosphatase activity and bilirubin) and fibrosis (hydroxyproline and hyaluronic acid) were measured 1 day and 1 to 24 weeks after DBTC- and DBTC/ethanol administration." | 3.70 | The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats. ( Hennighausen, G; Jonas, L; Merkord, J; Nizze, H; Weber, H, 1998) |
| "These mutated genes affect NAFLD by promoting liver steatosis (PNPLA3, MBOAT7, TM2SF6, PTPRD, FNDC5, IL-1B, PPARGC1A, UCP2, TCF7L2, SAMM50, IL-6, AGTR1, and NNMT), inflammation (PNPLA3, TNF-α, AGTR1, IL-17A, IL-1B, PTPRD, and GATAD2A), and fibrosis (IL-1B, PNPLA3, MBOAT7, TCF7L2, GATAD2A, IL-6, NNMT, UCP, AGTR1, and TM2SF6)." | 2.82 | Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and Fibrosis: A Narrative Review ( Dwi Astarini, F; Ratnasari, N; Wasityastuti, W, 2022) |
| "We examined the genetic background of nonalcoholic fatty liver disease (NAFLD) in the Japanese population, by performing a genome-wide association study (GWAS)." | 2.78 | Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan. ( Chayama, K; Hotta, K; Hyogo, H; Kitamoto, A; Kitamoto, T; Mizusawa, S; Nakajima, A; Nakamura, T; Nakao, K; Ochi, H; Sekine, A; Teranishi, H; Ueno, T; Yoneda, M, 2013) |
| "Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC)." | 2.66 | Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma. ( Goto, T; Hirotsu, Y; Kanda, T; Masuzaki, R; Moriyama, M; Omata, M, 2020) |
| "However, the development of hepatocellular carcinoma (HCC), even after the achievement of SVR, continues to be a serious problem." | 1.72 | Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication. ( Furusyo, N; Ikezaki, H; Matsumoto, Y; Murata, M; Ogawa, E; Ohta, A; Yamasaki, S, 2022) |
| "Significant liver fibrosis regression occurs after hepatitis C virus (HCV) therapy." | 1.72 | Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants. ( Avihingsanon, A; Chuaypen, N; Hiranrat, P; Siripongsakun, S; Tangkijvanich, P; Tanpowpong, N, 2022) |
| "In nonalcoholic fatty liver disease (NAFLD) the patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 variant is a contributor." | 1.72 | Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans. ( Andréasson, AC; Antonsson, M; Bergenholm, L; Carlsson, B; Dix, CI; Ekstedt, M; Ericson, E; Fjellström, O; Hansson, SF; Kechagias, S; Knöchel, J; Lee, R; Liljeblad, M; Lindén, D; Nasr, P; Schumi, J, 2022) |
| "Advanced fibrosis was diagnosed by liver biopsy or elastography." | 1.72 | Effect of common genetic variants on the risk of cirrhosis in non-alcoholic fatty liver disease during 20 years of follow-up. ( Ekstedt, M; Hagström, H; Holmer, M; Kechagias, S; Nasr, P; Romeo, S; Stål, P; Tavaglione, F; Wester, A; Zenlander, R, 2022) |
| "Insulin resistance is the strongest predictor of liver fibrosis stage and hepatic inflammation in patients with alcohol-related liver disease." | 1.72 | Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis. ( Detlefsen, S; Fernandes Jensen, MJ; Hansen, T; Israelsen, M; Juel, HB; Kjærgaard, M; Krag, A; Larsen, TR; Madsen, BS; Rasmussen, DN; Stender, S; Thiele, M, 2022) |
| "Chronic pancreatitis is considered a common gastrointestinal disorder, with significant morbidity and mortality." | 1.62 | Fraxetin prevented sodium fluoride-induced chronic pancreatitis in rats: Role of anti-inflammatory, antioxidant, antifibrotic and anti-apoptotic activities. ( Ahmed, N; Balaha, M; Geddawy, A; Kandeel, S, 2021) |
| "We recruited 515 patients with NAFLD (age 16-88 years, 280 female patients)." | 1.46 | Combined effects of the PNPLA3 rs738409, TM6SF2 rs58542926, and MBOAT7 rs641738 variants on NAFLD severity: a multicenter biopsy-based study. ( Bantel, H; Boettler, T; Demir, M; Geier, A; Kluwe, J; Krawczyk, M; Lammert, F; Pathil, A; Rau, M; Schattenberg, JM, 2017) |
| "Advanced liver fibrosis was neither associated with PNPLA3 (p = 0." | 1.42 | The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection. ( Aichelburg, MC; Bota, S; Bucsics, T; Ferenci, P; Grabmeier-Pfistershammer, K; Mandorfer, M; Payer, BA; Peck-Radosavljevic, M; Reiberger, T; Scheiner, B; Schwabl, P; Stättermayer, A; Trauner, M, 2015) |
| "Chronic pancreatitis was induced by repetitive intraperitoneal injections of caerulein in C57/BL mice followed by a consecutive administration of rhIL-1Ra (10mg/kg)." | 1.38 | Recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) attenuates caerulein-induced chronic pancreatitis in mice. ( Gao, J; Han, W; Qian, L; Shen, J; Wang, X; Wu, M; Xiang, D; Yang, L; Yu, Y; Zhang, J; Zhu, S, 2012) |
| "Mechanisms leading to acute pancreatitis after a fat-enriched meal combined with excess alcohol are incompletely understood." | 1.35 | Stimulation of stellate cells by injured acinar cells: a model of acute pancreatitis induced by alcohol and fat (VLDL). ( Alt, A; Bachem, MG; Bair, B; Beger, HG; Gross, H; Hamm, S; Kornmann, M; Mayer, J; Siech, M; Tian, X; Zhou, S; Zhou, Z, 2009) |
| "Troglitazone treatment significantly increased pancreatic wet weight and protein, DNA, and enzyme contents compared with those in the control rats." | 1.31 | Troglitazone stimulates pancreatic growth in congenitally CCK-A receptor-deficient OLETF rats. ( Akiyama, T; Fukumitsu, KI; Jia, DM; Otsuki, M; Tabaru, A, 2001) |
| " To evaluate the relationship between fibrosing colonopathy and supplemental pancreatic enzymes we reviewed our dosing of enzymes prior to fibrosing colonopathy development and then evaluated the subsequent effect of drastically reducing pancreatic enzyme dose." | 1.30 | Pancreatic enzyme supplementation in cystic fibrosis patients before and after fibrosing colonopathy. ( Chong, SK; Heilman, DK; Hollingsworth, J; Maguiness, KM; Stevens, JC, 1998) |
| " There was no relationship between enzyme dosage and colon thickness but simple regression identified a significant relationship (P < 0." | 1.30 | Colonic wall thickening is related to age and not dose of high strength pancreatin microspheres in children with cystic fibrosis. ( Atchley, JT; Connett, GJ; Fairhurst, JJ; Lucas, JS; Rolles, CJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (27.69) | 18.2507 |
| 2000's | 10 (15.38) | 29.6817 |
| 2010's | 19 (29.23) | 24.3611 |
| 2020's | 18 (27.69) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, M | 1 |
| Suzuki, J | 1 |
| Sato, S | 1 |
| Zenimaru, Y | 1 |
| Saito, R | 1 |
| Konoshita, T | 1 |
| Kraemer, FB | 1 |
| Ishizuka, T | 1 |
| Vilar-Gomez, E | 1 |
| Pirola, CJ | 1 |
| Sookoian, S | 1 |
| Wilson, LA | 1 |
| Liang, T | 1 |
| Chalasani, N | 1 |
| Ohta, A | 1 |
| Ogawa, E | 1 |
| Murata, M | 1 |
| Matsumoto, Y | 1 |
| Yamasaki, S | 1 |
| Ikezaki, H | 1 |
| Furusyo, N | 1 |
| Chuaypen, N | 1 |
| Siripongsakun, S | 1 |
| Hiranrat, P | 1 |
| Tanpowpong, N | 1 |
| Avihingsanon, A | 1 |
| Tangkijvanich, P | 1 |
| De Las Heras, M | 1 |
| Lacasta, D | 1 |
| Reséndiz, RA | 1 |
| Rivas, A | 1 |
| Garzianda, A | 1 |
| de Miguel, R | 1 |
| Ruiz, H | 1 |
| Castells, E | 1 |
| González, V | 1 |
| Ferrer, LM | 1 |
| Ericson, E | 1 |
| Bergenholm, L | 1 |
| Andréasson, AC | 1 |
| Dix, CI | 1 |
| Knöchel, J | 1 |
| Hansson, SF | 1 |
| Lee, R | 1 |
| Schumi, J | 1 |
| Antonsson, M | 1 |
| Fjellström, O | 1 |
| Nasr, P | 2 |
| Liljeblad, M | 1 |
| Carlsson, B | 1 |
| Kechagias, S | 2 |
| Lindén, D | 1 |
| Ekstedt, M | 2 |
| Dwi Astarini, F | 1 |
| Ratnasari, N | 1 |
| Wasityastuti, W | 1 |
| Holmer, M | 1 |
| Zenlander, R | 1 |
| Wester, A | 1 |
| Tavaglione, F | 1 |
| Romeo, S | 1 |
| Stål, P | 1 |
| Hagström, H | 1 |
| Han, X | 1 |
| Zhang, YL | 1 |
| Zhao, YX | 1 |
| Guo, SB | 1 |
| Yin, WP | 1 |
| Li, HH | 1 |
| Rao, M | 1 |
| Guo, G | 1 |
| Li, M | 1 |
| Chen, S | 1 |
| Chen, K | 1 |
| Chen, X | 1 |
| Song, J | 1 |
| Hu, S | 1 |
| Nadella, S | 1 |
| Ciofoaia, V | 1 |
| Cao, H | 1 |
| Kallakury, B | 1 |
| Tucker, RD | 1 |
| Smith, JP | 1 |
| Daijo, K | 1 |
| Nakahara, T | 1 |
| Inagaki, Y | 1 |
| Nanba, M | 1 |
| Nishida, Y | 1 |
| Uchikawa, S | 1 |
| Kodama, K | 1 |
| Oya, K | 1 |
| Morio, K | 1 |
| Fujino, H | 1 |
| Ono, A | 1 |
| Murakami, E | 1 |
| Yamauchi, M | 1 |
| Kawaoka, T | 1 |
| Miki, D | 1 |
| Tsuge, M | 1 |
| Hiramatsu, A | 1 |
| Hayes, CN | 1 |
| Imamura, M | 1 |
| Aikata, H | 1 |
| Ochi, H | 2 |
| Chayama, K | 2 |
| Lütt, F | 1 |
| Ehlers, L | 1 |
| Nizze, H | 3 |
| Jaster, R | 1 |
| Fang, S | 1 |
| Cai, Y | 1 |
| Lyu, F | 1 |
| Zhang, H | 2 |
| Wu, C | 2 |
| Zeng, Y | 1 |
| Fan, C | 1 |
| Zou, S | 1 |
| Zhang, Y | 1 |
| Li, P | 1 |
| Wang, L | 1 |
| Guan, M | 1 |
| Kanda, T | 1 |
| Goto, T | 1 |
| Hirotsu, Y | 1 |
| Masuzaki, R | 1 |
| Moriyama, M | 1 |
| Omata, M | 1 |
| Pennisi, G | 1 |
| Pipitone, RM | 1 |
| Cammà, C | 1 |
| Di Marco, V | 1 |
| Di Martino, V | 1 |
| Spatola, F | 1 |
| Zito, R | 1 |
| Craxì, A | 1 |
| Grimaudo, S | 1 |
| Petta, S | 1 |
| Inazumi, T | 1 |
| Yamada, K | 1 |
| Shirata, N | 1 |
| Sato, H | 2 |
| Taketomi, Y | 1 |
| Morita, K | 1 |
| Hohjoh, H | 1 |
| Tsuchiya, S | 1 |
| Oniki, K | 1 |
| Watanabe, T | 1 |
| Sasaki, Y | 1 |
| Oike, Y | 1 |
| Ogata, Y | 1 |
| Saruwatari, J | 1 |
| Murakami, M | 1 |
| Sugimoto, Y | 1 |
| Israelsen, M | 1 |
| Juel, HB | 1 |
| Detlefsen, S | 1 |
| Madsen, BS | 1 |
| Rasmussen, DN | 1 |
| Larsen, TR | 1 |
| Kjærgaard, M | 1 |
| Fernandes Jensen, MJ | 1 |
| Stender, S | 1 |
| Hansen, T | 1 |
| Krag, A | 1 |
| Thiele, M | 1 |
| Balaha, M | 1 |
| Ahmed, N | 1 |
| Geddawy, A | 1 |
| Kandeel, S | 1 |
| Kawamura, Y | 1 |
| Ikeda, K | 1 |
| Arase, Y | 1 |
| Fujiyama, S | 1 |
| Hosaka, T | 1 |
| Kobayashi, M | 1 |
| Saitoh, S | 1 |
| Sezaki, H | 1 |
| Akuta, N | 1 |
| Suzuki, F | 1 |
| Suzuki, Y | 1 |
| Kumada, H | 1 |
| Koo, BK | 1 |
| Joo, SK | 1 |
| Kim, D | 1 |
| Bae, JM | 1 |
| Park, JH | 1 |
| Kim, JH | 1 |
| Kim, W | 1 |
| Tang, W | 1 |
| Zhao, Z | 1 |
| Chong, Y | 1 |
| Liu, Q | 1 |
| Yang, J | 1 |
| Zhou, R | 1 |
| Lian, ZX | 1 |
| Liang, G | 1 |
| Guichelaar, MM | 1 |
| Gawrieh, S | 1 |
| Olivier, M | 1 |
| Viker, K | 1 |
| Krishnan, A | 1 |
| Sanderson, S | 1 |
| Malinchoc, M | 1 |
| Watt, KD | 1 |
| Swain, JM | 1 |
| Sarr, M | 1 |
| Charlton, MR | 1 |
| Kitamoto, T | 1 |
| Kitamoto, A | 1 |
| Yoneda, M | 1 |
| Hyogo, H | 1 |
| Nakamura, T | 1 |
| Teranishi, H | 1 |
| Mizusawa, S | 1 |
| Ueno, T | 1 |
| Nakajima, A | 1 |
| Nakao, K | 1 |
| Sekine, A | 1 |
| Hotta, K | 1 |
| Petrushenko, VV | 1 |
| Sukhodolia, SA | 1 |
| Falalieieva, TM | 1 |
| Berehova, TV | 1 |
| Mori, J | 1 |
| Patel, VB | 1 |
| Ramprasath, T | 1 |
| Alrob, OA | 1 |
| DesAulniers, J | 1 |
| Scholey, JW | 1 |
| Lopaschuk, GD | 1 |
| Oudit, GY | 1 |
| Matsuda, A | 1 |
| Makino, N | 1 |
| Tozawa, T | 1 |
| Shirahata, N | 1 |
| Honda, T | 1 |
| Ikeda, Y | 1 |
| Ito, M | 1 |
| Kakizaki, Y | 1 |
| Akamatsu, M | 1 |
| Ueno, Y | 1 |
| Kawata, S | 1 |
| Zhang, L | 1 |
| You, W | 1 |
| Peng, R | 1 |
| Zhu, Q | 1 |
| Yao, A | 1 |
| Li, X | 1 |
| Zhou, Y | 1 |
| Wang, X | 4 |
| Pu, L | 1 |
| Wu, J | 1 |
| Ali, M | 1 |
| Yopp, A | 1 |
| Gopal, P | 1 |
| Beg, MS | 1 |
| Zhu, H | 1 |
| Lee, W | 1 |
| Singal, AG | 1 |
| Grabliauskaite, K | 1 |
| Saponara, E | 1 |
| Reding, T | 1 |
| Bombardo, M | 1 |
| Seleznik, GM | 1 |
| Malagola, E | 1 |
| Zabel, A | 1 |
| Faso, C | 1 |
| Sonda, S | 1 |
| Graf, R | 1 |
| Xiao, W | 1 |
| Jiang, W | 1 |
| Shen, J | 3 |
| Yin, G | 1 |
| Fan, Y | 1 |
| Wu, D | 1 |
| Qiu, L | 1 |
| Yu, G | 1 |
| Xing, M | 1 |
| Hu, G | 1 |
| Wan, R | 1 |
| Scheiner, B | 1 |
| Mandorfer, M | 1 |
| Schwabl, P | 1 |
| Payer, BA | 1 |
| Bucsics, T | 1 |
| Bota, S | 1 |
| Aichelburg, MC | 1 |
| Grabmeier-Pfistershammer, K | 1 |
| Stättermayer, A | 1 |
| Ferenci, P | 1 |
| Trauner, M | 1 |
| Peck-Radosavljevic, M | 1 |
| Reiberger, T | 1 |
| Krawczyk, M | 1 |
| Rau, M | 1 |
| Schattenberg, JM | 1 |
| Bantel, H | 1 |
| Pathil, A | 1 |
| Demir, M | 1 |
| Kluwe, J | 1 |
| Boettler, T | 1 |
| Lammert, F | 1 |
| Geier, A | 1 |
| Karatas, A | 1 |
| Paksoy, M | 1 |
| Erzin, Y | 1 |
| Carkman, S | 1 |
| Gonenc, M | 1 |
| Ayan, F | 1 |
| Aydogan, F | 1 |
| Uzun, H | 1 |
| Durak, H | 1 |
| Siech, M | 1 |
| Zhou, Z | 1 |
| Zhou, S | 1 |
| Bair, B | 1 |
| Alt, A | 1 |
| Hamm, S | 1 |
| Gross, H | 1 |
| Mayer, J | 1 |
| Beger, HG | 1 |
| Tian, X | 1 |
| Kornmann, M | 1 |
| Bachem, MG | 1 |
| Valenti, L | 1 |
| Alisi, A | 1 |
| Galmozzi, E | 1 |
| Bartuli, A | 1 |
| Del Menico, B | 1 |
| Alterio, A | 1 |
| Dongiovanni, P | 1 |
| Fargion, S | 1 |
| Nobili, V | 1 |
| Samkharadze, T | 1 |
| Erkan, M | 1 |
| Reiser-Erkan, C | 1 |
| Demir, IE | 1 |
| Kong, B | 1 |
| Ceyhan, GO | 1 |
| Michalski, CW | 1 |
| Esposito, I | 1 |
| Friess, H | 1 |
| Kleeff, J | 1 |
| Gao, J | 1 |
| Zhang, J | 1 |
| Xiang, D | 1 |
| Qian, L | 1 |
| Yang, L | 1 |
| Zhu, S | 1 |
| Wu, M | 1 |
| Yu, Y | 1 |
| Han, W | 1 |
| Kanno, Y | 1 |
| Kawashita, E | 1 |
| Kokado, A | 1 |
| Okada, K | 1 |
| Ueshima, S | 1 |
| Matsuo, O | 1 |
| Matsuno, H | 1 |
| Inoue, M | 1 |
| Ino, Y | 1 |
| Gibo, J | 1 |
| Ito, T | 1 |
| Hisano, T | 1 |
| Arita, Y | 1 |
| Nawata, H | 1 |
| Jia, D | 1 |
| Taguchi, M | 1 |
| Otsuki, M | 2 |
| Monroe, L | 1 |
| Nowicki, M | 1 |
| Giles, H | 1 |
| Ruiz, F | 1 |
| Smyth, RL | 2 |
| Ashby, D | 1 |
| O'Hea, U | 1 |
| Burrows, E | 1 |
| Lewis, P | 1 |
| van Velzen, D | 3 |
| Dodge, JA | 2 |
| Oades, PJ | 2 |
| Bush, A | 2 |
| Ong, PS | 1 |
| Brereton, RJ | 1 |
| Mac Sweeney, EJ | 1 |
| Buchdahl, R | 1 |
| Rosenthal, M | 1 |
| Smyth, AR | 1 |
| Lloyd, DA | 1 |
| Heaf, DP | 1 |
| Pettei, MJ | 1 |
| Leonidas, JC | 1 |
| Levine, JJ | 1 |
| Gorvoy, JD | 1 |
| Freiman, JP | 1 |
| FitzSimmons, SC | 2 |
| Kapadia, C | 1 |
| Reichard, KW | 1 |
| Vinocur, CD | 1 |
| Franco, M | 1 |
| Crisci, KL | 1 |
| Flick, JA | 1 |
| Billmire, DF | 1 |
| Schidlow, DV | 1 |
| Weintraub, WH | 1 |
| Burkhart, GA | 1 |
| Borowitz, D | 1 |
| Grand, RJ | 1 |
| Hammerstrom, T | 1 |
| Durie, PR | 1 |
| Lloyd-Still, JD | 1 |
| Lowenfels, AB | 1 |
| Lee, J | 1 |
| Ip, W | 1 |
| Durie, P | 1 |
| Merkord, J | 3 |
| Jonas, L | 2 |
| Weber, H | 3 |
| Kröning, G | 2 |
| Hennighausen, G | 3 |
| Stevens, JC | 1 |
| Maguiness, KM | 1 |
| Hollingsworth, J | 1 |
| Heilman, DK | 1 |
| Chong, SK | 1 |
| Moss, RL | 1 |
| Musemeche, CA | 1 |
| Feddersen, RM | 1 |
| Connett, GJ | 1 |
| Lucas, JS | 1 |
| Atchley, JT | 1 |
| Fairhurst, JJ | 1 |
| Rolles, CJ | 1 |
| Bakowski, M | 1 |
| Bansi, DS | 1 |
| Price, A | 1 |
| Russell, C | 1 |
| Sarner, M | 1 |
| Jia, DM | 1 |
| Fukumitsu, KI | 1 |
| Tabaru, A | 1 |
| Akiyama, T | 1 |
| Furukawa, F | 1 |
| Nishikawa, A | 1 |
| Kasahara, K | 1 |
| Miyauchi, M | 1 |
| Nakamura, H | 1 |
| Son, HY | 1 |
| Uchida, K | 1 |
| Hirose, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1/2 Trial to Test the Safety of a CCK Receptor Antagonist, Proglumide, in Management of Chronic Pancreatitis Symptoms and Pain for 12 to 24 Months[NCT05551858] | Phase 1/Phase 2 | 32 participants (Anticipated) | Interventional | 2022-11-17 | Recruiting | ||
| Establishment of Non-alcoholic Fatty Liver Disease Cohort and Development of Markers to Predict Histologic Progression of Liver Fibrosis[NCT02206841] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2014-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for 1-anilino-8-naphthalenesulfonate and Cirrhosis
| Article | Year |
|---|---|
Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and Fibrosis: A Narrative Review
Topics: Fibronectins; Fibrosis; Genetic Predisposition to Disease; Humans; Inflammation; Interleukin-6; Lipa | 2022 |
Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Apoptosis; Carcinoma, Hepatocellular; Diet, High-Fat; Dis | 2020 |
PNPLA3 polymorphisms (rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: a meta-analysis.
Topics: Alanine Transaminase; Alleles; Asian People; Case-Control Studies; Databases, Bibliographic; Fibrosi | 2015 |
1 trial available for 1-anilino-8-naphthalenesulfonate and Cirrhosis
| Article | Year |
|---|---|
Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.
Topics: Actinin; Adult; Age Factors; Aged; Alanine Transaminase; Asian People; Aspartate Aminotransferases; | 2013 |
61 other studies available for 1-anilino-8-naphthalenesulfonate and Cirrhosis
| Article | Year |
|---|---|
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy.
Topics: Animals; Cardiomyopathies; Fibrosis; Lipase; Lipolysis; Mice; Myocytes, Cardiac; Sterol Esterase; Tr | 2022 |
PNPLA3 rs738409 and risk of fibrosis in NAFLD: Exploring mediation pathways through intermediate histological features.
Topics: Fibrosis; Genetic Predisposition to Disease; Humans; Inflammation; Lipase; Liver; Membrane Proteins; | 2022 |
Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication.
Topics: Acyltransferases; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Genotype; Hepacivirus; Hepa | 2022 |
Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants.
Topics: Antiviral Agents; Fatty Liver; Fibrosis; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; H | 2022 |
Chronic pithomycotoxicosis associated with obstructive rhinopathy in sheep.
Topics: Alanine Transaminase; Animals; Fibrosis; Lipase; Sheep; Sheep Diseases; Sporidesmins | 2022 |
Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans.
Topics: Acyltransferases; Alleles; Animals; Fibrosis; Humans; Inflammation; Lipase; Membrane Proteins; Non-a | 2022 |
Effect of common genetic variants on the risk of cirrhosis in non-alcoholic fatty liver disease during 20 years of follow-up.
Topics: Diabetes Mellitus, Type 2; Fibrosis; Follow-Up Studies; Humans; Lipase; Liver Cirrhosis; Membrane Pr | 2022 |
Adipose Triglyceride Lipase Deficiency Aggravates Angiotensin II-Induced Atrial Fibrillation by Reducing Peroxisome Proliferator-Activated Receptor α Activation in Mice.
Topics: Acyltransferases; Angiotensin II; Animals; Atrial Fibrillation; Fibrosis; Lipase; Male; Mice; Mice, | 2023 |
The homozygous variant c.245G > A/p.G82D in PNPLA2 is associated with arrhythmogenic cardiomyopathy phenotypic manifestations.
Topics: Amino Acid Sequence; Animals; Arrhythmogenic Right Ventricular Dysplasia; Base Sequence; Disease Mod | 2019 |
Cholecystokinin Receptor Antagonist Therapy Decreases Inflammation and Fibrosis in Chronic Pancreatitis.
Topics: Animals; Ceruletide; Chronic Disease; Disease Models, Animal; Fibrosis; Inflammation; Lipase; Mice; | 2020 |
Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alleles; Biomarkers; Biopsy; Disease Progressi | 2020 |
Different characteristics of chronic dibutyltin dichloride-induced pancreatitis and cholangitis in mouse and rat.
Topics: Animals; Cholangitis; Chronic Disease; Disease Models, Animal; Fibrosis; Lipase; Liver; Male; Mice; | 2020 |
Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation.
Topics: 3T3-L1 Cells; 8-Hydroxy-2'-Deoxyguanosine; Adenylate Kinase; Adipocytes, Brown; Adipogenesis; Adipos | 2020 |
PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease.
Topics: Fibrosis; Genetic Predisposition to Disease; Humans; Lipase; Liver; Liver Cirrhosis; Membrane Protei | 2021 |
Prostaglandin E
Topics: Adipocytes; Adipose Tissue, White; Adiposity; Adult; Animals; Cell Line; Collagen; Diet; Dinoproston | 2020 |
Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis.
Topics: Alcohol Drinking; Cholesterol; Cross-Sectional Studies; Fatty Liver, Alcoholic; Fibrosis; Genetic Pr | 2022 |
Fraxetin prevented sodium fluoride-induced chronic pancreatitis in rats: Role of anti-inflammatory, antioxidant, antifibrotic and anti-apoptotic activities.
Topics: Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Coumarins; Cytokines; Fibrosis | 2021 |
New Discriminant Method for Identifying the Aggressive Disease Phenotype of Non-alcoholic Fatty Liver Disease.
Topics: Adult; Age Factors; Aged; Biopsy; Body Mass Index; Disease Progression; Female; Fibrosis; Genotype; | 2017 |
Additive effects of PNPLA3 and TM6SF2 on the histological severity of non-alcoholic fatty liver disease.
Topics: Adipose Tissue; Cohort Studies; Fibrosis; Genetic Association Studies; Genetic Variation; Homeostasi | 2018 |
Tandem Enzymatic Self-Assembly and Slow Release of Dexamethasone Enhances Its Antihepatic Fibrosis Effect.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascomycota; Dexamethasone; F | 2018 |
Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity.
Topics: Adult; Alleles; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 1; Fatty Liver; Female; F | 2013 |
[New approach for treatment of chronic pancreatitis, caused by L-arginine, in rats].
Topics: Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclooxygenase 2 Inhibitors; F | 2013 |
Angiotensin 1-7 mediates renoprotection against diabetic nephropathy by reducing oxidative stress, inflammation, and lipotoxicity.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diabetic Nephropathies; Fibrosis; Forkhead | 2014 |
Pancreatic fat accumulation, fibrosis, and acinar cell injury in the Zucker diabetic fatty rat fed a chronic high-fat diet.
Topics: Acinar Cells; Amylases; Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Type 2; | 2014 |
A Variant in PNPLA3 Associated With Fibrosis Progression but not Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Female; Fibrosis; G | 2016 |
Inactivation of TGFβ receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis.
Topics: Acinar Cells; Amylases; Animals; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Prolifer | 2016 |
Retinoic Acid Ameliorates Pancreatic Fibrosis and Inhibits the Activation of Pancreatic Stellate Cells in Mice with Experimental Chronic Pancreatitis via Suppressing the Wnt/β-Catenin Signaling Pathway.
Topics: Actins; Active Transport, Cell Nucleus; Animals; Apoptosis; Axin Protein; Cells, Cultured; Ceruletid | 2015 |
The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection.
Topics: Adult; Age Factors; Alleles; Biopsy; Cohort Studies; Coinfection; Cross-Sectional Studies; Disease P | 2015 |
Combined effects of the PNPLA3 rs738409, TM6SF2 rs58542926, and MBOAT7 rs641738 variants on NAFLD severity: a multicenter biopsy-based study.
Topics: Acyltransferases; Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Biopsy; Fatty Liver; Female; | 2017 |
The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of pancreatic fibrosis in an experimental model of severe hyperstimulation and obstruction pancreatitis.
Topics: Amylases; Animals; Collagen Type I; Disease Models, Animal; Female; Fibrosis; Hyaluronic Acid; Lipas | 2008 |
Stimulation of stellate cells by injured acinar cells: a model of acute pancreatitis induced by alcohol and fat (VLDL).
Topics: Acute Disease; Amylases; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Dose-Response Rela | 2009 |
I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease.
Topics: Adolescent; Child; Fatty Liver; Female; Fibrosis; Humans; Lipase; Male; Membrane Proteins; Polymorph | 2010 |
Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer.
Topics: Animals; Cell Line; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Fibrosis; Hum | 2011 |
Recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) attenuates caerulein-induced chronic pancreatitis in mice.
Topics: Amylases; Animals; Ceruletide; Collagen; Disease Models, Animal; Fibrosis; Humans; Hydroxyproline; I | 2012 |
Alpha2-antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F(2α) synthesis through adipose triglyceride lipase/calcium-independent phospholipase A(2).
Topics: alpha-2-Antiplasmin; Animals; Bleomycin; Cells, Cultured; Collagen; Dinoprost; Dinoprostone; Disease | 2013 |
The role of monocyte chemoattractant protein-1 in experimental chronic pancreatitis model induced by dibutyltin dichloride in rats.
Topics: Amylases; Animals; Chemokine CCL2; Chronic Disease; Fibrosis; Hydroxyproline; Injections, Intravenou | 2002 |
Preventive and therapeutic effects of the protease inhibitor camostat on pancreatic fibrosis and atrophy in CCK-1 receptor-deficient rats.
Topics: Actins; Amylases; Animals; Atrophy; Eating; Esters; Fibrosis; Gabexate; Guanidines; Interleukin-6; L | 2005 |
Clinical quiz. Diagnosis: fibrosing colonopathy.
Topics: Barium Sulfate; Colon; Constriction, Pathologic; Contrast Media; Cystic Fibrosis; Dose-Response Rela | 2006 |
Fibrosing colonopathy in cystic fibrosis: results of a case-control study.
Topics: Adolescent; Amylases; Bromelains; Case-Control Studies; Cathartics; Child; Child, Preschool; Cohort | 1995 |
High-strength pancreatic enzyme supplements and large-bowel stricture in cystic fibrosis.
Topics: Amylases; Bromelains; Cecum; Child, Preschool; Colon; Constriction, Pathologic; Cystic Fibrosis; Dru | 1994 |
Relation of thickening of colon wall to pancreatic-enzyme treatment in cystic fibrosis.
Topics: Adolescent; Adult; Amylases; Child; Child, Preschool; Colon; Cystic Fibrosis; Endopeptidases; Fibros | 1995 |
Colonic strictures in children with cystic fibrosis on low-strength pancreatic enzymes.
Topics: Amylases; Animals; Bromelains; Colon; Colonic Diseases; Cystic Fibrosis; Drug Combinations; Fibrosis | 1995 |
Strictures of ascending colon in cystic fibrosis and high-strength pancreatic enzymes.
Topics: Abdominal Pain; Adolescent; Child; Child, Preschool; Colon; Colonic Diseases; Constriction, Patholog | 1994 |
Pancolonic disease in cystic fibrosis and high-dose pancreatic enzyme therapy.
Topics: Child, Preschool; Chronic Disease; Chylous Ascites; Colon; Colonic Diseases; Cystic Fibrosis; Diarrh | 1994 |
Colonic strictures in patients with cystic fibrosis: results of a survey of 114 cystic fibrosis care centers in the United States.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Colon; Colonic Diseases; Cystic Fibrosis; | 1996 |
Fibrosing colonopathy in cystic fibrosis: results of a case-control study.
Topics: Amylases; Case-Control Studies; Colon; Colonic Diseases; Cystic Fibrosis; Endopeptidases; Fibrosis; | 1996 |
Fibrosing colonopathy in children with cystic fibrosis.
Topics: Adolescent; Child; Child, Preschool; Colon; Cystic Fibrosis; Female; Fibrosis; Humans; Infant; Infan | 1996 |
Fibrosing colonopathy in children with cystic fibrosis.
Topics: Child; Child, Preschool; Colon; Colonic Diseases; Cystic Fibrosis; Female; Fibrosis; Humans; Infant; | 1997 |
High-dose pancreatic-enzyme supplements and fibrosing colonopathy in children with cystic fibrosis.
Topics: Case-Control Studies; Child; Child, Preschool; Colon; Colonic Diseases; Cystic Fibrosis; Dose-Respon | 1997 |
Is fibrosing colonopathy an immune mediated disease?
Topics: Animals; Child; Child, Preschool; Colon; Cystic Fibrosis; Drug Administration Schedule; Female; Fibr | 1997 |
Acute interstitial pancreatitis in rats induced by dibutyltin dichloride (DBTC): pathogenesis and natural course of lesions.
Topics: Acute Disease; alpha-Amylases; Animals; Bile Ducts; Fibrosis; Ligation; Lipase; Liver; Male; Microsc | 1997 |
Pancreatic enzyme supplementation in cystic fibrosis patients before and after fibrosing colonopathy.
Topics: Adolescent; Child; Child, Preschool; Colon; Colonic Diseases; Cystic Fibrosis; Exocrine Pancreatic I | 1998 |
Progressive pan-colonic fibrosis secondary to oral administration of pancreatic enzymes.
Topics: Child; Colon; Constriction, Pathologic; Cystic Fibrosis; Disease Progression; Fibrosis; Humans; Inte | 1998 |
The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats.
Topics: Administration, Oral; Amylases; Animals; Drug Synergism; Edema; Ethanol; Fibrosis; Hyaluronic Acid; | 1998 |
Colonic wall thickening is related to age and not dose of high strength pancreatin microspheres in children with cystic fibrosis.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Colon; Colonic Diseases; Constriction, Pathologic; | 1999 |
Pancreatic enzymes and fibrosing colonopathy.
Topics: Child; Colonic Diseases; Dose-Response Relationship, Drug; Fibrosis; Humans; Lipase; Pancreatic Extr | 1999 |
Fibrosing colonopathy.
Topics: Colon; Crohn Disease; Cystic Fibrosis; Diet; Dietary Fiber; Fibrosis; Humans; Lipase | 2000 |
Fibrosing colonopathy in an adult owing to over use of pancreatic enzyme supplements.
Topics: Adult; Colon; Colonic Diseases; Diarrhea; Drug Administration Schedule; Female; Fibrosis; Humans; Li | 2000 |
Troglitazone stimulates pancreatic growth in congenitally CCK-A receptor-deficient OLETF rats.
Topics: Aging; Amylases; Animals; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Fibrosis; Homeostasis; | 2001 |
Involvement of lipid peroxidation in spontaneous pancreatitis in WBN/Kob rats.
Topics: Aging; Aldehydes; Amylases; Animals; Edema; Fibrosis; Hemorrhage; Immunohistochemistry; Lipase; Lipi | 2001 |
Repeated administration of a mild acute toxic dose of di-n-butyltin dichloride at intervals of 3 weeks induces severe lesions in pancreas and liver of rats.
Topics: Alkaline Phosphatase; Animals; Bile Ducts; Bilirubin; Dose-Response Relationship, Drug; Fibrosis; Hy | 2001 |