Page last updated: 2024-10-21

1-anilino-8-naphthalenesulfonate and Chronic Hepatitis C

1-anilino-8-naphthalenesulfonate has been researched along with Chronic Hepatitis C in 70 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Research Excerpts

ExcerptRelevanceReference
" Single nucleotide polymorphisms (SNPs) near the epidermal growth factor (EGF) (rs4444903), IL28B (rs12979860), and PNPLA3 (rs738409) loci are associated with treatment response, fibrosis, and hepatocellular carcinoma in non-transplant hepatitis C, but allograft population data are limited."3.83Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study. ( Chung, RT; Corey, KE; Curry, MP; Fuchs, BC; Gao, T; Gogela, NA; Gordon, FD; Johnson, KB; King, LY; Kothari, D; Lee, JH; Lin, MV; Misdraji, J; Mueller, JL; Nephew, LD; Simpson, MA; Tanabe, KK; Wei, L; Zheng, H, 2016)
"The incidence of hepatocellular carcinoma (HCC) is increasing in Western countries."2.50Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data. ( Bontempi, G; Burza, MA; Corradini, SG; Deltenre, P; Devière, J; Donati, B; Falleti, E; Franchimont, D; Guyot, E; Hamza, S; Henrion, J; Hillon, P; Mathurin, P; Moreno, C; Nahon, P; Nischalke, HD; Romeo, S; Spengler, U; Toniutto, P; Trépo, E; Valenti, L, 2014)
"However, the development of hepatocellular carcinoma (HCC), even after the achievement of SVR, continues to be a serious problem."1.72Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication. ( Furusyo, N; Ikezaki, H; Matsumoto, Y; Murata, M; Ogawa, E; Ohta, A; Yamasaki, S, 2022)
"Significant liver fibrosis regression occurs after hepatitis C virus (HCV) therapy."1.72Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants. ( Avihingsanon, A; Chuaypen, N; Hiranrat, P; Siripongsakun, S; Tangkijvanich, P; Tanpowpong, N, 2022)
"Nonalcoholic fatty liver disease (NAFLD), insulin resistance and liver fibrosis are prevalent in individuals co-infected with HIV type 1 (HIV-1)/hepatitis C virus (HCV), even after HCV eradication."1.62Single nucleotide polymorphisms in PNPLA3, ADAR-1 and IFIH1 are associated with advanced liver fibrosis in patients co-infected with HIV-1//hepatitis C virus. ( Bechini, J; Clotet, B; de Cid, R; Franco, S; Galván-Femenía, I; Horneros, J; Llibre, JM; Martínez, MA; Ouchi, D; Perez, R; Soldevila, L; Tenesa, M; Tural, C, 2021)
"Among 261 patients with liver cirrhosis, rs738409 (GG) genotype was not associated with time-to-HCC development on multivariate Cox regression (P = 0."1.48Association between PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma in Asian chronic hepatitis C patients: A longitudinal study. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Huang, CM; Hung, CH; Kee, KM; Kuo, YH; Lin, JT; Lin, MT; Lu, SN; Tsai, MC; Tseng, PL; Wang, JH; Wu, CK; Yen, YH, 2018)
"The study included 317 individuals with liver cirrhosis, 154 individuals with liver fibrosis, and 498 controls."1.46PNPLA3 and RNF7 Gene Variants are Associated with the Risk of Developing Liver Fibrosis and Cirrhosis in an Eastern European Population. ( Kiudelis, G; Kondrackiene, J; Kupcinskas, J; Kupcinskas, L; Lammert, F; Petrenkiene, V; Skieceviciene, J; Steponaitiene, R; Sumskiene, J; Valantiene, I; Varkalaitė, G, 2017)
"Acute pancreatitis is a rare complication of PEG-IFN-α administration."1.43Acute pancreatitis associated with pegylated interferon-alpha-2a therapy in chronic hepatitis C. ( Bae, WK; Choi, JW; Kim, JG; Kim, JW; Kim, KA; Lee, JS; Paik, WH; Song, TJ, 2016)
"Patients with advanced liver fibrosis had higher proportions of the GG genotype (14."1.42Association of diabetes and PNPLA3 genetic variants with disease severity of patients with chronic hepatitis C virus infection. ( Chen, SC; Chuang, WL; Dai, CY; Hsieh, MH; Hsieh, MY; Huang, CF; Huang, CI; Huang, JF; Liang, PC; Lin, YH; Lin, ZY; Tai, CM; Yang, HL; Yeh, ML; Yu, ML, 2015)
"Histological features of steatohepatitis in CHC were assessed using the Bedossa classification."1.42PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C. ( Abate, ML; Bugianesi, E; Cabibi, D; Cammà, C; Craxì, A; Di Marco, V; Eslam, M; George, J; Grimaudo, S; Macaluso, FS; McLeod, D; Petta, S; Pipitone, RM; Rosso, C; Smedile, A; Vanni, E, 2015)
"Advanced liver fibrosis was neither associated with PNPLA3 (p = 0."1.42The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection. ( Aichelburg, MC; Bota, S; Bucsics, T; Ferenci, P; Grabmeier-Pfistershammer, K; Mandorfer, M; Payer, BA; Peck-Radosavljevic, M; Reiberger, T; Scheiner, B; Schwabl, P; Stättermayer, A; Trauner, M, 2015)
"Hepatic cirrhosis was associated with a higher aspartate aminotransferase/platelet ratio index (APRI), no fatty change of the liver, higher BMI and higher AFP levels."1.39No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV. ( Jiang, X; Kanda, T; Miyamura, T; Nakamoto, S; Nakamura, M; Wu, S; Yokosuka, O, 2013)
"Insulin resistance is more common in carriers of the T allele of SNP rs12979860 than in CC homozygotes and may partly explain the poor outcome of peginterferon/ribavirin therapy in these patients."1.38Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C. ( Beinhardt, S; Datz, C; Ferenci, P; Hofer, H; Krebs, M; Rutter, K; Scherzer, TM; Stadlmayr, A; Stättermayer, AF; Steindl-Munda, P; Trauner, M; Wrba, F, 2012)
"We performed a 2-stage GWA study of liver fibrosis progression related to HCV infection."1.38Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. ( Abel, L; Argiro, L; Bibert, S; Bochud, PY; Boland, A; Booth, DR; Bourlière, M; Bousquet, L; Bréchot, C; Casanova, JL; Cerny, A; Dufour, JF; George, J; Guergnon, J; Halfon, P; Heim, MH; Hirsch, H; Jacobson, IM; Jouanguy, E; Kutalik, Z; Malinverni, R; Martinetti, G; Moradpour, D; Müllhaupt, B; Munteanu, M; Nalpas, B; Negro, F; Patin, E; Pol, S; Poynard, T; Rice, CM; Semela, D; Stewart, G; Suppiah, V; Talal, AH; Theodorou, I, 2012)
"Two patients experienced episodes of acute pancreatitis shortly after starting treatment with interferon alfa-2b (IFN-alpha) for a chronic hepatitis C infection."1.31Acute pancreatitis attributed to the use of interferon alfa-2b. ( Bekkering, FC; Belaiche, J; Brouwer, JT; Delwaide, J; Eland, IA; Houbiers, G; Rasch, MC; Stricker, BH; Sturkenboom, MJ, 2000)
"Patients with liver cirrhosis had serum levels of amylase and lipase significantly higher than both the healthy subjects and the patients with CAH, while no significant differences were found in serum levels of these enzymes in patients with CAH as compared to the healthy subjects."1.30Serum pancreatic enzyme concentrations in chronic viral liver diseases. ( Andreone, P; Barakat, B; Bernardi, M; Billi, P; Cursaro, C; Fiocchi, M; Gramenzi, A; Miglio, F; Morselli-Labate, AM; Pezzilli, R; Sama, C, 1999)

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.43)18.2507
2000's4 (5.71)29.6817
2010's55 (78.57)24.3611
2020's10 (14.29)2.80

Authors

AuthorsStudies
Franco, S1
Horneros, J1
Soldevila, L1
Ouchi, D1
Galván-Femenía, I1
de Cid, R1
Tenesa, M1
Bechini, J1
Perez, R1
Llibre, JM1
Clotet, B1
Tural, C1
Martínez, MA1
Gavril, OI1
Arhire, LI1
Gavrilescu, O1
Dranga, M1
Barboi, O1
Gavril, RS1
Popescu, R1
Cijevschi Prelipcean, C1
Trifan, AV1
Mihai, C1
Ohta, A1
Ogawa, E1
Murata, M1
Matsumoto, Y1
Yamasaki, S1
Ikezaki, H1
Furusyo, N1
Chuaypen, N2
Siripongsakun, S1
Hiranrat, P1
Tanpowpong, N1
Avihingsanon, A1
Tangkijvanich, P2
Senkerikova, R1
Frankova, S1
Jirsa, M1
Kreidlova, M1
Merta, D1
Neroldova, M1
Chmelova, K1
Spicak, J1
Sperl, J1
Crisan, D1
Grigorescu, M1
Crisan, N1
Craciun, R1
Lupsor, M1
Radu, C1
Grigorescu, MD1
Suciu, A1
Epure, F1
Avram, L1
Leach, N1
Youssef, SS1
Abbas, EAER1
Youness, RA1
Elemeery, MN1
Nasr, AS1
Seif, S1
Magri, MC3
Manchiero, C3
Prata, TVG2
Nunes, AKDS3
Oliveira Junior, JS1
Dantas, BP3
Tengan, FM3
Miki, D1
Akita, T1
Kurisu, A1
Kawaoka, T1
Nakajima, T1
Hige, S1
Karino, Y1
Toyoda, H1
Kumada, T1
Tsuge, M1
Hiramatsu, A1
Imamura, M1
Aikata, H1
Hayes, CN1
Honda, K1
Seike, M1
Akuta, N1
Kobayashi, M2
Kumada, H2
Tanaka, J1
Chayama, K1
Agrawal, T1
Gaggar, A1
Subramanian, M1
Kottilil, S1
Choudhary, A1
Rao, PN1
Shah, S1
Trehanpati, N1
Alvarez, MSM1
Iogi, AA1
Alves, GM1
Oliveira, AIN1
Malta, FM1
Zitelli, PMY1
Salles, APM1
Gomes-Gouvea, MS1
Nastri, ACS1
Pinho, JRR1
Carrilho, FJ1
Oliveira, CP1
Mendes-Corrêa, MC1
Pessoa, MG1
Mazo, DF1
Kupcinskas, J1
Valantiene, I1
Varkalaitė, G1
Steponaitiene, R1
Skieceviciene, J1
Sumskiene, J1
Petrenkiene, V1
Kondrackiene, J1
Kiudelis, G1
Lammert, F1
Kupcinskas, L1
Huang, CM2
Chang, KC2
Hung, CH2
Chiu, KW2
Lu, SN3
Wang, JH2
Chen, CH2
Kee, KM2
Kuo, YH2
Tsai, MC2
Tseng, PL2
Lin, MT2
Wu, CK2
Hu, TH2
Cho, CL1
Yen, YH2
Lin, JT1
Mazza, CC1
Barone, AA1
Jiménez-Sousa, MÁ2
Gómez-Moreno, AZ1
Pineda-Tenor, D1
Sánchez-Ruano, JJ1
Fernández-Rodríguez, A1
Artaza-Varasa, T1
Gómez-Sanz, A1
Martín-Vicente, M1
Vázquez-Morón, S2
Resino, S2
Mandorfer, M3
Scheiner, B2
Stättermayer, AF4
Schwabl, P3
Paternostro, R1
Bauer, D1
Schaefer, B1
Zoller, H1
Peck-Radosavljevic, M3
Trauner, M4
Reiberger, T3
Ferenci, P5
Ferlitsch, A2
Sherman, KE1
Rouster, SD1
Kang, M1
Umbleja, T1
Sterling, R1
Butt, AA1
Zampino, R3
Macera, M4
Cirillo, G5
Pafundi, PC1
Rinaldi, L1
Coppola, N5
Pisaturo, M3
Adinolfi, LE4
Miraglia Del Giudice, E3
Ingrosso, D1
Capasso, R1
Raksayot, M1
Khlaiphuengsin, A1
Pinjaroen, N1
Treeprasertsuk, S1
Poovorawan, Y1
Tanaka, Y2
Boemio, A2
Marrone, A3
Sagnelli, E3
Perrone, L1
Trépo, E2
Nahon, P2
Bontempi, G1
Valenti, L8
Falleti, E1
Nischalke, HD1
Hamza, S1
Corradini, SG1
Burza, MA2
Guyot, E2
Donati, B2
Spengler, U1
Hillon, P1
Toniutto, P1
Henrion, J1
Franchimont, D2
Devière, J2
Mathurin, P1
Moreno, C2
Romeo, S3
Deltenre, P1
Dongiovanni, P5
Fares, R1
Lombardi, R1
Mancina, RM1
Nakamura, M1
Kanda, T1
Nakamoto, S1
Miyamura, T1
Jiang, X1
Wu, S1
Yokosuka, O1
Florio, A1
Del Giudice, EM2
Moritou, Y2
Ikeda, F2
Iwasaki, Y2
Baba, N1
Takaguchi, K1
Senoh, T1
Nagano, T1
Takeuchi, Y2
Yasunaka, T2
Ohnishi, H2
Miyake, Y2
Takaki, A2
Nouso, K2
Yamamoto, K2
Payer, BA2
Steiner, S1
Aichelburg, MC2
Obermayer-Pietsch, B1
Grabmeier-Pfistershammer, K2
De Nicola, S3
Aghemo, A4
Cheroni, C1
D'Ambrosio, R1
Pedrazzini, M1
Marabita, F1
Donnici, L1
Maggioni, M2
Fargion, S6
Colombo, M4
De Francesco, R1
Huang, CF2
Dai, CY2
Yeh, ML2
Huang, CI2
Tai, CM1
Hsieh, MH1
Liang, PC1
Lin, YH1
Hsieh, MY2
Yang, HL2
Huang, JF2
Lin, ZY2
Chen, SC2
Yu, ML2
Chuang, WL2
Yasui, K1
Kawaguchi, T1
Shima, T1
Mitsuyoshi, H1
Seki, K1
Sendo, R1
Mizuno, M1
Itoh, Y1
Matsuda, F1
Okanoue, T1
Rosa, Z1
Stanzione, M1
Grandone, A2
Petta, S2
Vanni, E1
Bugianesi, E1
Rosso, C1
Cabibi, D2
Cammà, C2
Di Marco, V2
Eslam, M1
Grimaudo, S2
Macaluso, FS2
McLeod, D1
Pipitone, RM2
Abate, ML1
Smedile, A1
George, J2
Craxì, A2
Chen, JJ1
Chen, YL1
Maida, M1
Sferrazza, S1
Ali, M1
Yopp, A1
Gopal, P1
Beg, MS1
Zhu, H1
Lee, W1
Singal, AG1
Tamaki, N1
Kurosaki, M1
Higuchi, M1
Takada, H1
Nakakuki, N1
Yasui, Y1
Suzuki, S1
Tsuchiya, K1
Nakanishi, H1
Itakura, J1
Takahashi, Y1
Ogawa, S1
Asahina, Y1
Izumi, N1
Enache, EL1
Sin, A1
Bancu, L1
Ramière, C1
Diaz, O1
André, P1
Enache, LS1
Fan, JH1
Xiang, MQ1
Li, QL1
Shi, HT1
Guo, JJ1
Bucsics, T1
Bota, S1
Stättermayer, A1
Berenguer, J1
García-Álvarez, M1
Gutierrez-Rivas, M1
Aldámiz-Echevarria, T1
Tejerina, F1
Diez, C1
Sagnelli, C1
Merli, M1
Uberti-Foppa, C1
Hasson, H1
Salpietro, S1
Minichini, C1
Lazzarin, A1
Mueller, JL1
King, LY1
Johnson, KB1
Gao, T1
Nephew, LD1
Kothari, D1
Simpson, MA1
Zheng, H1
Wei, L1
Corey, KE1
Misdraji, J1
Lee, JH1
Lin, MV1
Gogela, NA1
Fuchs, BC1
Tanabe, KK1
Gordon, FD1
Curry, MP1
Chung, RT2
Choi, JW1
Lee, JS1
Paik, WH1
Song, TJ1
Kim, JW1
Bae, WK1
Kim, KA1
Kim, JG1
Núñez-Torres, R1
Macías, J1
Mancebo, M1
Frías, M1
Dolci, G1
Téllez, F1
Merino, D1
Merchante, N1
Gómez-Mateos, J1
Guaraldi, G1
Rivero-Juárez, A1
Pineda, JA1
Real, LM1
Cai, T1
Dufour, JF2
Muellhaupt, B1
Gerlach, T1
Heim, M1
Moradpour, D2
Cerny, A2
Malinverni, R2
Kaddai, V1
Bochud, M1
Negro, F2
Bochud, PY2
Müller, T1
Buch, S1
Berg, T1
Hampe, J1
Stickel, F1
Rumi, M1
Galmozzi, E1
Del Menico, B1
Fracanzani, AL2
Rametta, R2
Friedman, SL1
Pradat, P1
Potthoff, A1
Momozawa, Y1
Quertinmont, E1
Gustot, T1
Lemmers, A1
Berthillon, P1
Amininejad, L1
Chevallier, M1
Schlué, J1
Kreipe, H1
Manns, M1
Trépo, C1
Sninsky, J1
Wedemeyer, H1
Kalambokis, GN1
Tsianos, EV1
do O, NT1
Eurich, D1
Trautwein, C1
Neuhaus, P1
Neumann, UP1
Wasmuth, HE1
Schaefer, EA1
Maggioni, P1
Motta, BM2
Rumi, MG1
Clark, PJ1
Thompson, AJ1
Zhu, Q1
Vock, DM1
Zhu, M1
Patel, K1
Harrison, SA1
Naggie, S1
Ge, D1
Tillmann, HL1
Urban, TJ1
Shianna, K1
Fellay, J1
Goodman, Z1
Noviello, S1
Pedicone, LD1
Afdhal, N1
Sulkowski, M1
Albrecht, JK1
Goldstein, DB1
McHutchison, JG1
Muir, AJ1
Rutter, K1
Beinhardt, S1
Scherzer, TM1
Stadlmayr, A1
Hofer, H1
Wrba, F1
Steindl-Munda, P1
Krebs, M1
Datz, C1
Patin, E1
Kutalik, Z1
Guergnon, J1
Bibert, S1
Nalpas, B1
Jouanguy, E1
Munteanu, M1
Bousquet, L1
Argiro, L1
Halfon, P1
Boland, A1
Müllhaupt, B1
Semela, D1
Heim, MH1
Hirsch, H1
Martinetti, G1
Suppiah, V1
Stewart, G1
Booth, DR1
Casanova, JL1
Bréchot, C1
Rice, CM1
Talal, AH1
Jacobson, IM1
Bourlière, M1
Theodorou, I1
Poynard, T1
Pol, S1
Abel, L1
Miyashita, M1
Ito, T1
Sakaki, M1
Kajiwara, A1
Nozawa, H1
Hiroishi, K1
Imawari, M1
Hagihara, H1
Kuwaki, K1
Nakamura, S1
Shiraha, H1
Ruscica, M1
Steffani, L1
Canavesi, E1
Mozzi, E1
Roviaro, G1
Magni, P1
Rembeck, K1
Maglio, C1
Lagging, M1
Christensen, PB1
Färkkilä, M1
Langeland, N1
Buhl, MR1
Pedersen, C1
Mørch, K1
Norkrans, G1
Hellstrand, K1
Lindh, M1
Pirazzi, C1
Westin, J1
Sutton, A1
Rufat, P1
Laguillier, C1
Mansouri, A1
Moreau, R1
Ganne-Carrié, N1
Beaugrand, M1
Charnaux, N1
Trinchet, JC1
Yoffe, B1
Bagri, AS1
Tran, T1
Dural, AT1
Shtenberg, KM1
Khaoustov, VI1
Katakura, Y1
Yotsuyanagi, H1
Hashizume, K1
Okuse, C1
Okuse, N1
Nishikawa, K1
Suzuki, M1
Iino, S1
Itoh, F1
Chen, CL1
Yang, HI1
Yang, WS1
Liu, CJ1
Chen, PJ1
You, SL1
Wang, LY1
Sun, CA1
Chen, DS1
Chen, CJ1
Pezzilli, R1
Andreone, P1
Morselli-Labate, AM1
Sama, C1
Billi, P1
Cursaro, C1
Barakat, B1
Gramenzi, A1
Fiocchi, M1
Miglio, F1
Bernardi, M1
Eland, IA1
Rasch, MC1
Sturkenboom, MJ1
Bekkering, FC1
Brouwer, JT1
Delwaide, J1
Belaiche, J1
Houbiers, G1
Stricker, BH1

Reviews

4 reviews available for 1-anilino-8-naphthalenesulfonate and Chronic Hepatitis C

ArticleYear
Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:6

    Topics: Carcinoma, Hepatocellular; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis, Alcoholic; Liver N

2014
PNPLA3 I148M polymorphism and progressive liver disease.
    World journal of gastroenterology, 2013, Nov-07, Volume: 19, Issue:41

    Topics: Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Disease Progression; Fatty Liver; Fatty Liver, A

2013
PNPLA3 rs738409 Polymorphism Associated with Hepatic Steatosis and Advanced Fibrosis in Patients with Chronic Hepatitis C Virus: A Meta-Analysis.
    Gut and liver, 2016, May-23, Volume: 10, Issue:3

    Topics: Asian People; Fatty Liver; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Membrane Proteins;

2016
The impact of human gene polymorphisms on HCV infection and disease outcome.
    Seminars in liver disease, 2011, Volume: 31, Issue:4

    Topics: Antiviral Agents; Disease Progression; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hep

2011

Trials

2 trials available for 1-anilino-8-naphthalenesulfonate and Chronic Hepatitis C

ArticleYear
PNPLA3 Gene Polymorphisms in HCV/HIV-Coinfected Individuals.
    Digestive diseases and sciences, 2018, Volume: 63, Issue:11

    Topics: Adult; Cohort Studies; Female; Hepatitis C, Chronic; HIV Infections; Humans; Lipase; Male; Membrane

2018
PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection.
    BMC medical genetics, 2012, Sep-14, Volume: 13

    Topics: Adult; Alleles; Antiviral Agents; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic;

2012

Other Studies

64 other studies available for 1-anilino-8-naphthalenesulfonate and Chronic Hepatitis C

ArticleYear
Single nucleotide polymorphisms in PNPLA3, ADAR-1 and IFIH1 are associated with advanced liver fibrosis in patients co-infected with HIV-1//hepatitis C virus.
    AIDS (London, England), 2021, 12-01, Volume: 35, Issue:15

    Topics: Acyltransferases; Adenosine Deaminase; Coinfection; Hepacivirus; Hepatitis C, Chronic; HIV Infection

2021
Role of PNPLA3 in the Assessment and Monitoring of Hepatic Steatosis and Fibrosis in Patients with Chronic Hepatitis C Infection Who Achieved a Sustained Virologic Response.
    Medicina (Kaunas, Lithuania), 2021, Oct-24, Volume: 57, Issue:11

    Topics: Antiviral Agents; Fatty Liver; Genotype; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Memb

2021
Impact of the PNPLA3 genotype on the risk of hepatocellular carcinoma after hepatitis C virus eradication.
    Journal of medical virology, 2022, Volume: 94, Issue:10

    Topics: Acyltransferases; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Genotype; Hepacivirus; Hepa

2022
Improvement of liver fibrosis, but not steatosis, after HCV eradication as assessment by MR-based imaging: Role of metabolic derangement and host genetic variants.
    PloS one, 2022, Volume: 17, Issue:6

    Topics: Antiviral Agents; Fatty Liver; Fibrosis; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; H

2022
PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.
    PloS one, 2019, Volume: 14, Issue:9

    Topics: Alleles; Carcinoma, Hepatocellular; Case-Control Studies; Cross-Sectional Studies; Female; Genetic P

2019
Association between PNPLA3[G]/I148M variant, steatosis and fibrosis stage in hepatitis C virus - genetic matters.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2019, Volume: 70, Issue:4

    Topics: Antiviral Agents; Disease Progression; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Interferon

2019
PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression.
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:2

    Topics: Acyltransferases; Fatty Liver; Hepatitis C, Chronic; Humans; Interferons; Lipase; Liver Cirrhosis; M

2022
The influence of gene-chronic hepatitis C virus infection on hepatic fibrosis and steatosis.
    Diagnostic microbiology and infectious disease, 2020, Volume: 97, Issue:2

    Topics: Adult; Aged; Brazil; Carrier Proteins; Fatty Liver; Female; Genetic Association Studies; Genotype; H

2020
PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication.
    Journal of gastroenterology, 2020, Volume: 55, Issue:12

    Topics: Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Female; Follow-Up Studies; Hepatitis C,

2020
PNPLA3 polymorphisms are associated with raised alanine aminotransferase levels in hepatitis C virus genotype 3.
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2020, Volume: 21, Issue:4

    Topics: Adult; Alanine Transaminase; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; India; Interleukin

2020
Study of CXCL9-11 gene polymorphisms in liver fibrosis among patients with chronic hepatitis C.
    Pathogens and disease, 2021, 03-20, Volume: 79, Issue:3

    Topics: Adult; Aged; Alleles; Chemokine CXCL10; Chemokine CXCL11; Chemokine CXCL9; Female; Genetic Predispos

2021
The role of PNPLA3 and TM6SF2 polymorphisms on liver fibrosis and metabolic abnormalities in Brazilian patients with chronic hepatitis C.
    BMC gastroenterology, 2021, Feb-23, Volume: 21, Issue:1

    Topics: Aged; Brazil; Cross-Sectional Studies; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chr

2021
PNPLA3 and RNF7 Gene Variants are Associated with the Risk of Developing Liver Fibrosis and Cirrhosis in an Eastern European Population.
    Journal of gastrointestinal and liver diseases : JGLD, 2017, Volume: 26, Issue:1

    Topics: Adult; c-Mer Tyrosine Kinase; Case-Control Studies; Female; Genetic Predisposition to Disease; Genom

2017
Impact of PNPLA3 and IFNL3 polymorphisms on hepatic steatosis in Asian patients with chronic hepatitis C.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Adult; Aged; Alleles; Asian People; Fatty Liver; Female; Genetic Association Studies; Genetic Predis

2017
Association between PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma in Asian chronic hepatitis C patients: A longitudinal study.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2018, Volume: 117, Issue:9

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Cross-Sectional Studies; Female; Genetic Predisposition to D

2018
The rs738409 polymorphism of the PNPLA3 gene is associated with hepatic steatosis and fibrosis in Brazilian patients with chronic hepatitis C.
    BMC infectious diseases, 2017, 12-19, Volume: 17, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Brazil; DNA; Fatty Liver; Female; Gene Frequency; Genotype;

2017
PNPLA3 rs738409 polymorphism is associated with liver fibrosis progression in patients with chronic hepatitis C: A repeated measures study.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2018, Volume: 103

    Topics: Adult; Disease Progression; Disease Susceptibility; Elasticity Imaging Techniques; Female; Genetic A

2018
Impact of patatin-like phospholipase domain containing 3 rs738409 G/G genotype on hepatic decompensation and mortality in patients with portal hypertension.
    Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:4

    Topics: Adult; Aged; Cross-Sectional Studies; Fatty Liver; Female; Genetic Predisposition to Disease; Genoty

2018
No effect of MTP polymorphisms on PNPLA3 in HCV-correlated steatosis.
    Le infezioni in medicina, 2018, 09-01, Volume: 26, Issue:3

    Topics: Adult; Anthropometry; Biopsy; Carrier Proteins; Fatty Liver; Female; Genetic Predisposition to Disea

2018
Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma.
    Journal of gastroenterology, 2019, Volume: 54, Issue:5

    Topics: Acyltransferases; Aged; Alleles; Carcinoma, Hepatocellular; Case-Control Studies; Chondroitin Sulfat

2019
Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C.
    Journal of viral hepatitis, 2013, Volume: 20, Issue:8

    Topics: Abdominal Fat; Adult; Aged; Aged, 80 and over; Apolipoprotein C-III; Fatty Liver; Female; Genotype;

2013
No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Adult; Aged; Asian People; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; Hepaciv

2013
PNPLA3 I148M variant as a risk factor for carotid atherosclerosis in chronic hepatitis C.
    International journal of cardiology, 2014, Mar-01, Volume: 172, Issue:1

    Topics: Adult; Aged; Carotid Artery Diseases; Female; Genetic Predisposition to Disease; Genetic Variation;

2014
Impact of comorbid hepatic steatosis on treatment of chronic hepatitis C in Japanese patients and the relationship with genetic polymorphism of IL28B, PNPLA3 and LDL receptor.
    Acta medica Okayama, 2014, Volume: 68, Issue:1

    Topics: Aged; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Lipase; Logistic

2014
Revisiting liver disease progression in HIV/HCV-coinfected patients: the influence of vitamin D, insulin resistance, immune status, IL28B and PNPLA3.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:3

    Topics: Adult; Coinfection; Disease Progression; Female; Genotype; Hepatitis C; Hepatitis C, Chronic; HIV; H

2015
Interaction between PNPLA3 I148M variant and age at infection in determining fibrosis progression in chronic hepatitis C.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Disease Progression; Fatty Liver; Gene Frequency; Genetic Pred

2014
Association of diabetes and PNPLA3 genetic variants with disease severity of patients with chronic hepatitis C virus infection.
    Journal of hepatology, 2015, Volume: 62, Issue:3

    Topics: Adult; Aged; Cohort Studies; Diabetes Complications; Female; Genes, Dominant; Genes, Recessive; Gene

2015
Effect of PNPLA3 rs738409 variant (I148 M) on hepatic steatosis, necroinflammation, and fibrosis in Japanese patients with chronic hepatitis C.
    Journal of gastroenterology, 2015, Volume: 50, Issue:8

    Topics: Adult; Aged; Cross-Sectional Studies; Fatty Liver; Female; Genetic Predisposition to Disease; Hepati

2015
TM6SF2 E167K variant is associated with severe steatosis in chronic hepatitis C, regardless of PNPLA3 polymorphism.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:8

    Topics: Adult; Analysis of Variance; Antiviral Agents; Cohort Studies; Female; Genetic Predisposition to Dis

2015
PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C.
    Alimentary pharmacology & therapeutics, 2015, Volume: 41, Issue:10

    Topics: Adult; Cohort Studies; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lip

2015
PNPLA3 genetic variants determine hepatic steatosis in non-obese chronic hepatitis C patients.
    Scientific reports, 2015, Jul-03, Volume: 5

    Topics: Adult; Asian People; Body Mass Index; Fatty Liver; Female; Genetic Association Studies; Genetic Pred

2015
TM6SF2 rs58542926 is not associated with steatosis and fibrosis in large cohort of patients with genotype 1 chronic hepatitis C.
    Liver international : official journal of the International Association for the Study of the Liver, 2016, Volume: 36, Issue:2

    Topics: Adult; Cohort Studies; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Interferons; Interleukins;

2016
A Variant in PNPLA3 Associated With Fibrosis Progression but not Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2016, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Female; Fibrosis; G

2016
Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Aged; Antiviral Agents; Disease Progression; Fatty Liver; Female; Genome-Wide Association Study; Gen

2015
Duplex High-Resolution Melting Assay for the Simultaneous Genotyping of IL28B rs12979860 and PNPLA3 rs738409 Polymorphisms in Chronic Hepatitis C Patients.
    International journal of molecular sciences, 2015, Sep-14, Volume: 16, Issue:9

    Topics: Adult; Case-Control Studies; Female; Genotyping Techniques; Hepatitis C, Chronic; Humans; Interferon

2015
The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Adult; Age Factors; Alleles; Biopsy; Cohort Studies; Coinfection; Cross-Sectional Studies; Disease P

2015
Impact of patatin-like phospholipase domain-containing 3 gene polymorphism (rs738409) on severity of liver disease in HIV/hepatitis C virus-coinfected patients.
    AIDS (London, England), 2016, Jan-28, Volume: 30, Issue:3

    Topics: Adult; Biopsy; Coinfection; Cross-Sectional Studies; Female; Genetic Association Studies; Genotyping

2016
Impact of PNPLA3 variants on liver histology of 168 patients with HIV infection and chronic hepatitis C.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016, Volume: 22, Issue:4

    Topics: Adult; Amino Acid Substitution; Fatty Liver; Female; Genetic Predisposition to Disease; Genotype; He

2016
Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study.
    Clinical transplantation, 2016, Volume: 30, Issue:4

    Topics: Adult; Allografts; Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Disease Progression;

2016
Acute pancreatitis associated with pegylated interferon-alpha-2a therapy in chronic hepatitis C.
    Clinical and molecular hepatology, 2016, Volume: 22, Issue:1

    Topics: Amylases; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interfe

2016
The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Adult; Alleles; Coinfection; Cross-Sectional Studies; Disease Progression; Elasticity Imaging Techni

2016
Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis.
    Journal of hepatology, 2011, Volume: 55, Issue:3

    Topics: Adult; Carrier Proteins; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; I

2011
Distinct, alcohol-modulated effects of PNPLA3 genotype on progression of chronic hepatitis C.
    Journal of hepatology, 2011, Volume: 55, Issue:3

    Topics: Alcohol Drinking; Fatty Liver; Genotype; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Memb

2011
Patatin-like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:3

    Topics: Adult; Alanine Transaminase; Fatty Liver; Female; gamma-Glutamyltransferase; Hepatitis C, Chronic; H

2011
Focus.
    Journal of hepatology, 2011, Volume: 55, Issue:1

    Topics: Alcohol Drinking; alpha-Fetoproteins; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription F

2011
Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Belgium; Cross-Sectional Studies; Disease Progression; Fatty Liver; F

2011
Raised sympathetic activity and blood ammonia could increase sensitivity to infections in patients with cirrhosis and refractory ascites who are using beta-blockers.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:4

    Topics: End Stage Liver Disease; Female; Genetic Markers; Hepatitis C, Chronic; Humans; Lipase; Liver Transp

2011
The common I148 M variant of PNPLA3 does not predict fibrosis progression after liver transplantation for hepatitis C.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:4

    Topics: Cohort Studies; Disease Progression; End Stage Liver Disease; Female; Genetic Markers; Graft Rejecti

2011
Patatin-like phospholipase domain containing-3 Ile148Met and fibrosis progression after liver transplantation.
    Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:4

    Topics: End Stage Liver Disease; Female; Genetic Markers; Hepatitis C, Chronic; Humans; Lipase; Liver Transp

2011
Modulation of the effect of PNPLA3 I148M mutation on steatosis and liver damage by alcohol intake in patients with chronic hepatitis C.
    Journal of hepatology, 2011, Volume: 55, Issue:6

    Topics: Fatty Liver; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis; Membrane Proteins

2011
Implications of PNPLA3 polymorphism in chronic hepatitis C patients receiving peginterferon plus ribavirin.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:12

    Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Hu

2012
The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:8

    Topics: Adult; Aged; Fatty Liver; Female; Genotype; Hepatitis C, Chronic; Humans; Interferons; Interleukins;

2012
Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C.
    Journal of hepatology, 2012, Volume: 57, Issue:3

    Topics: Adult; Alleles; Body Mass Index; Confidence Intervals; Fatty Liver; Female; Genotype; Hepatitis C, C

2012
Understanding the role of PNPLA3 genetic variants in patients with chronic hepatitis C infection.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:8

    Topics: Fatty Liver; Hepatitis C, Chronic; Humans; Lipase; Membrane Proteins; Polymorphism, Single Nucleotid

2012
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.
    Gastroenterology, 2012, Volume: 143, Issue:5

    Topics: Adult; Apoptosis; c-Mer Tyrosine Kinase; Disease Progression; Eye Proteins; Female; Genome-Wide Asso

2012
Genetic polymorphism in cyclooxygenase-2 promoter affects hepatic inflammation and fibrosis in patients with chronic hepatitis C.
    Journal of viral hepatitis, 2012, Volume: 19, Issue:9

    Topics: Asian People; Cyclooxygenase 2; Disease Progression; Female; Genetic Predisposition to Disease; Hepa

2012
The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis.
    Journal of gastroenterology, 2013, Volume: 48, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Carcinoma, Hepatocellular; Female; Follow-Up Studie

2013
The I148M PNPLA3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls.
    BMC gastroenterology, 2012, Aug-16, Volume: 12

    Topics: Adiponectin; Adult; Aged; Alleles; Case-Control Studies; Fatty Liver; Female; Genetic Predisposition

2012
PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis.
    Journal of hepatology, 2013, Volume: 58, Issue:2

    Topics: Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Incide

2013
Hyperlipasemia associated with hepatitis C virus.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:8

    Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Hepacivirus; Hepatiti

2003
Pancreatic involvement in chronic viral hepatitis.
    World journal of gastroenterology, 2005, Jun-21, Volume: 11, Issue:23

    Topics: Adult; Aged; Amylases; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Lipase; Male; Mid

2005
Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan.
    Gastroenterology, 2008, Volume: 135, Issue:1

    Topics: Adult; Carbolines; Carcinoma, Hepatocellular; Diabetes Mellitus; Female; Follow-Up Studies; Hepatiti

2008
Serum pancreatic enzyme concentrations in chronic viral liver diseases.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aged; Amylases; Chronic Disease; Female; Hepatitis B, Chronic; Hepatitis C, Chron

1999
Acute pancreatitis attributed to the use of interferon alfa-2b.
    Gastroenterology, 2000, Volume: 119, Issue:1

    Topics: Abdominal Pain; Acute Disease; Adult; Amylases; Hepatitis C, Chronic; Humans; Injections, Subcutaneo

2000