1-anilino-8-naphthalenesulfonate has been researched along with Cachexia in 10 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Peripheral LIF administered to mice caused >50% loss of adipose tissue and >10% reduction in body weight despite only transient hypophagia due to decreasing leptin." | 7.88 | Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. ( Arora, GK; Guo, T; Gupta, A; Infante, RE; Iyengar, P; Narayanan, S, 2018) |
| " Peripheral LIF administered to mice caused >50% loss of adipose tissue and >10% reduction in body weight despite only transient hypophagia due to decreasing leptin." | 3.88 | Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin. ( Arora, GK; Guo, T; Gupta, A; Infante, RE; Iyengar, P; Narayanan, S, 2018) |
| "Cachexia is a term used to describe the poor status of a patient suffering from a benign disease (Crohn's disease, chronic heart and kidney failure) as well as from a malignant disease." | 2.44 | [Molecular mechanisms and its clinical impact in cancer cachexia]. ( Bachmann, J; Friess, H; Martignoni, ME, 2008) |
| "Cachexia is the main cause of mortality in advanced cancer patients." | 1.46 | Insulin, not glutamine dipeptide, reduces lipases expression and prevents fat wasting and weight loss in Walker 256 tumor-bearing rats. ( Bazotte, RB; Carpinelli, ÂR; da Silva, FG; de Fatima Silva, F; de Morais, H; de Souza, HM; Graciano, MFR; Martins, MIL; Mazucco, TL; Silva, MO, 2017) |
| "Cancer cachexia is a multifactorial metabolic syndrome characterized by marked loss of adipose tissue and skeletal muscle." | 1.46 | Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer. ( Alcântara, PSM; Batista, ML; Lira, FS; Oller do Nascimento, CM; Otoch, JP; Oyama, LM; Seelaender, M; Silvério, R, 2017) |
| "Cancer cachexia is a debilitating condition that impacts patient morbidity, mortality, and quality of life and for which effective therapies are lacking." | 1.42 | Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia. ( Bekaii-Saab, T; Bloomston, M; Chen, CS; Frankhouser, DE; Guttridge, DC; He, WA; Hsu, EC; Kulp, SK; Lai, IL; Lesinski, GB; Marcucci, G; Mo, X; Tseng, YC; Yan, PS, 2015) |
| "Cachexia is a multifactorial wasting syndrome most common in patients with cancer that is characterized by the uncontrolled loss of adipose and muscle mass." | 1.37 | Adipose triglyceride lipase contributes to cancer-associated cachexia. ( Das, SK; Diwoky, C; Eder, S; Gorkiewicz, G; Guertl, B; Haemmerle, G; Hoefler, G; Kumari, P; Schauer, S; Tamilarasan, KP; Temmel, H; Trauner, M; Vesely, P; Zechner, R; Zimmermann, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Morais, H | 1 |
| de Fatima Silva, F | 1 |
| da Silva, FG | 1 |
| Silva, MO | 1 |
| Graciano, MFR | 1 |
| Martins, MIL | 1 |
| Carpinelli, ÂR | 1 |
| Mazucco, TL | 1 |
| Bazotte, RB | 1 |
| de Souza, HM | 1 |
| Silvério, R | 1 |
| Lira, FS | 1 |
| Oyama, LM | 1 |
| Oller do Nascimento, CM | 1 |
| Otoch, JP | 1 |
| Alcântara, PSM | 1 |
| Batista, ML | 1 |
| Seelaender, M | 1 |
| Arora, GK | 1 |
| Gupta, A | 1 |
| Narayanan, S | 1 |
| Guo, T | 1 |
| Iyengar, P | 1 |
| Infante, RE | 1 |
| Das, SK | 2 |
| Hoefler, G | 2 |
| Tseng, YC | 1 |
| Kulp, SK | 1 |
| Lai, IL | 1 |
| Hsu, EC | 1 |
| He, WA | 1 |
| Frankhouser, DE | 1 |
| Yan, PS | 1 |
| Mo, X | 1 |
| Bloomston, M | 1 |
| Lesinski, GB | 1 |
| Marcucci, G | 1 |
| Guttridge, DC | 1 |
| Bekaii-Saab, T | 1 |
| Chen, CS | 1 |
| Bachmann, J | 1 |
| Friess, H | 1 |
| Martignoni, ME | 1 |
| Eder, S | 1 |
| Schauer, S | 1 |
| Diwoky, C | 1 |
| Temmel, H | 1 |
| Guertl, B | 1 |
| Gorkiewicz, G | 1 |
| Tamilarasan, KP | 1 |
| Kumari, P | 1 |
| Trauner, M | 1 |
| Zimmermann, R | 1 |
| Vesely, P | 1 |
| Haemmerle, G | 1 |
| Zechner, R | 1 |
| Arner, P | 1 |
| Fearon, KC | 1 |
| Mainguet, P | 1 |
| Thys, O | 1 |
| Paulet, P | 1 |
| Kiekens, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Biochemical and Functional Biomarkers of Cachexia in Cancer Patients[NCT03191955] | 120 participants (Anticipated) | Observational | 2015-11-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for 1-anilino-8-naphthalenesulfonate and Cachexia
| Article | Year |
|---|---|
The role of triglyceride lipases in cancer associated cachexia.
Topics: Animals; Cachexia; Humans; Lipase; Lipid Metabolism; Neoplasms | 2013 |
[Molecular mechanisms and its clinical impact in cancer cachexia].
Topics: Cachexia; Cytokines; Humans; Lipase; Pancreatic Neoplasms; Prognosis; Proteoglycans; Signal Transduc | 2008 |
8 other studies available for 1-anilino-8-naphthalenesulfonate and Cachexia
| Article | Year |
|---|---|
Insulin, not glutamine dipeptide, reduces lipases expression and prevents fat wasting and weight loss in Walker 256 tumor-bearing rats.
Topics: Adipose Tissue; Animals; Cachexia; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Insuli | 2017 |
Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer.
Topics: Adipokines; Adipose Tissue, White; Animals; Blotting, Western; Body Weight; Cachexia; Eating; Lipase | 2017 |
Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin.
Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Cachexia; Cell Line; Cytokine Receptor gp130; Cyto | 2018 |
Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia.
Topics: Adenocarcinoma; Adipose Tissue; Administration, Oral; Animals; Cachexia; Carcinoma, Lewis Lung; Colo | 2015 |
Adipose triglyceride lipase contributes to cancer-associated cachexia.
Topics: Adipose Tissue, White; Animals; Blood Glucose; Body Mass Index; Body Weight; Cachexia; Cytokines; Fa | 2011 |
Medicine. Lipases in cachexia.
Topics: Adipocytes; Adipose Tissue; Animals; Cachexia; Humans; Lipase; Lipolysis; Lung Neoplasms; Melanoma, | 2011 |
Cancer cachexia and fat-muscle physiology.
Topics: Adipose Tissue; Animals; Cachexia; Disease Models, Animal; Humans; Lipase; Lipolysis; Mice; Muscle, | 2011 |
A syndrome of polyvalent deficiencies after gastrectomy.
Topics: Alcoholism; Blood Protein Disorders; Cachexia; Carbohydrate Metabolism; Chymotrypsin; Deficiency Dis | 1972 |