1-anilino-8-naphthalenesulfonate has been researched along with Alzheimer Disease in 22 studies
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity and type 2 diabetes mellitus are the most extended current chronic diseases and also Alzheimer pathology which is a progressive degenerative neurological disorder." | 1.62 | Inhibition of enzymes associated with metabolic and neurological disorder by dried pomegranate sheets as a function of pomegranate cultivar and fruit puree. ( Cano-Lamadrid, M; Carbonell-Barrachina, ÁA; Hernández, F; Lech, K; Nowicka, P; Tkacz, K; Turkiewicz, IP; Wojdyło, A, 2021) |
| "Alzheimer's disease is characterized in part by the accumulation of full-length tau proteins into intracellular filamentous inclusions." | 1.33 | Triggers of full-length tau aggregation: a role for partially folded intermediates. ( Chirita, CN; Congdon, EE; Kuret, J; Yin, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Göransson, AL | 1 |
| Nilsson, KP | 1 |
| Kågedal, K | 1 |
| Brorsson, AC | 1 |
| Menden, A | 1 |
| Hall, D | 1 |
| Hahn-Townsend, C | 1 |
| Broedlow, CA | 1 |
| Joshi, U | 1 |
| Pearson, A | 1 |
| Crawford, F | 1 |
| Evans, JE | 1 |
| Klatt, N | 1 |
| Crynen, S | 1 |
| Mullan, M | 1 |
| Ait-Ghezala, G | 1 |
| Sanderson, JM | 1 |
| Cano-Lamadrid, M | 1 |
| Tkacz, K | 1 |
| Turkiewicz, IP | 1 |
| Nowicka, P | 1 |
| Hernández, F | 1 |
| Lech, K | 1 |
| Carbonell-Barrachina, ÁA | 1 |
| Wojdyło, A | 1 |
| Wenzel, TJ | 1 |
| Klegeris, A | 1 |
| Yun, SM | 1 |
| Park, JY | 1 |
| Seo, SW | 1 |
| Song, J | 1 |
| Loli, H | 1 |
| Narwal, SK | 1 |
| Saun, NK | 1 |
| Gupta, R | 1 |
| Amin, N | 1 |
| Jovanova, O | 1 |
| Adams, HH | 1 |
| Dehghan, A | 1 |
| Kavousi, M | 1 |
| Vernooij, MW | 1 |
| Peeters, RP | 1 |
| de Vrij, FM | 1 |
| van der Lee, SJ | 1 |
| van Rooij, JG | 1 |
| van Leeuwen, EM | 1 |
| Chaker, L | 1 |
| Demirkan, A | 1 |
| Hofman, A | 1 |
| Brouwer, RW | 1 |
| Kraaij, R | 1 |
| Willems van Dijk, K | 1 |
| Hankemeier, T | 1 |
| van Ijcken, WF | 1 |
| Uitterlinden, AG | 1 |
| Niessen, WJ | 1 |
| Franco, OH | 1 |
| Kushner, SA | 1 |
| Ikram, MA | 1 |
| Tiemeier, H | 1 |
| van Duijn, CM | 1 |
| Laws, SM | 1 |
| Eckart, K | 1 |
| Friedrich, P | 1 |
| Eisele, T | 1 |
| Kurz, A | 1 |
| Förstl, H | 1 |
| Riemenschneider, M | 1 |
| Du, J | 1 |
| Wang, Z | 1 |
| Xiao, Z | 1 |
| Wang, J | 1 |
| Chen, W | 2 |
| Wang, P | 1 |
| Zeng, H | 1 |
| Burgess, BL | 1 |
| McIsaac, SA | 1 |
| Naus, KE | 1 |
| Chan, JY | 1 |
| Tansley, GH | 1 |
| Yang, J | 1 |
| Miao, F | 1 |
| Ross, CJ | 1 |
| van Eck, M | 1 |
| Hayden, MR | 1 |
| van Nostrand, W | 1 |
| St George-Hyslop, P | 1 |
| Westaway, D | 1 |
| Wellington, CL | 1 |
| Zhu, H | 1 |
| Taylor, JW | 1 |
| Bennett, DA | 1 |
| Younkin, SG | 1 |
| Estus, S | 1 |
| Mahley, RW | 1 |
| Ji, ZS | 1 |
| Farooqui, AA | 2 |
| Horrocks, LA | 2 |
| Kallberg, Y | 1 |
| Gustafsson, M | 1 |
| Persson, B | 1 |
| Thyberg, J | 1 |
| Johansson, J | 1 |
| Liss, L | 1 |
| Koh, M | 1 |
| Lee, H | 1 |
| Lee, Y | 1 |
| Lee, M | 1 |
| Younan, ND | 1 |
| Viles, JH | 1 |
| Bolognesi, B | 1 |
| Kumita, JR | 1 |
| Barros, TP | 1 |
| Esbjorner, EK | 1 |
| Luheshi, LM | 1 |
| Crowther, DC | 1 |
| Wilson, MR | 1 |
| Dobson, CM | 1 |
| Favrin, G | 1 |
| Yerbury, JJ | 1 |
| Otzen, DE | 1 |
| Miron, S | 1 |
| Akke, M | 1 |
| Oliveberg, M | 1 |
| Chirita, CN | 1 |
| Congdon, EE | 1 |
| Yin, H | 1 |
| Kuret, J | 1 |
4 reviews available for 1-anilino-8-naphthalenesulfonate and Alzheimer Disease
| Article | Year |
|---|---|
Novel multi-target directed ligand-based strategies for reducing neuroinflammation in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cathepsin B; Dinoprosto | 2018 |
Lipases in Medicine: An Overview.
Topics: Alzheimer Disease; Animals; Atherosclerosis; Cystic Fibrosis; Humans; Lipase; Medicine; Neoplasms; O | 2015 |
Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E.
Topics: Alzheimer Disease; Animals; Apolipoproteins E; Biological Transport, Active; Cell Membrane; Chylomic | 1999 |
Lipid peroxides in the free radical pathophysiology of brain diseases.
Topics: Alzheimer Disease; Animals; Brain; Brain Diseases; Brain Ischemia; Down Syndrome; Free Radicals; Hum | 1998 |
18 other studies available for 1-anilino-8-naphthalenesulfonate and Alzheimer Disease
| Article | Year |
|---|---|
Identification of distinct physiochemical properties of toxic prefibrillar species formed by Aβ peptide variants.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Cell Line; Fluore | 2012 |
Exogenous lipase administration alters gut microbiota composition and ameliorates Alzheimer's disease-like pathology in APP/PS1 mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Clostridiales; Disease Models, Animal; Gastrointe | 2022 |
Far from Inert: Membrane Lipids Possess Intrinsic Reactivity That Has Consequences for Cell Biology.
Topics: Acetyl-CoA Hydrolase; Acyl Coenzyme A; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Membr | 2020 |
Inhibition of enzymes associated with metabolic and neurological disorder by dried pomegranate sheets as a function of pomegranate cultivar and fruit puree.
Topics: Acetylcholinesterase; alpha-Amylases; alpha-Glucosidases; Alzheimer Disease; Butyrylcholinesterase; | 2021 |
Association of plasma endothelial lipase levels on cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; Cholesterol, HDL; Cognitive Dysfuncti | 2019 |
Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms.
Topics: Adult; Alleles; Alzheimer Disease; Cholesterol, HDL; Depression; Depressive Disorder; Exome; Exons; | 2017 |
No association of lipase C polymorphisms with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Female; Genetic Markers; Genetic Predisposition to Di | 2010 |
Therapeutic potential of lipase inhibitor orlistat in Alzheimer's disease.
Topics: Alzheimer Disease; Enzyme Inhibitors; Humans; Lactones; Lipase; Models, Theoretical; Orlistat | 2009 |
Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Asian People; ATP Binding Cassette Transporter | 2012 |
Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting | 2006 |
Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Genetic Predisposition to Disease; Humans; Lipas | 2008 |
Prediction of amyloid fibril-forming proteins.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Animals; Candida; Databases, | 2001 |
Stimulation of lipolytic enzymes in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Carboxylic Ester Hydrolases; Cell Membrane; Digly | 1988 |
Characterization of early-stage amyloid aggregates by incorporating extrinsic fluorescence and atomic force microscopy.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonate | 2014 |
A Comparison of Three Fluorophores for the Detection of Amyloid Fibers and Prefibrillar Oligomeric Assemblies. ThT (Thioflavin T); ANS (1-Anilinonaphthalene-8-sulfonic Acid); and bisANS (4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid).
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonate | 2015 |
ANS binding reveals common features of cytotoxic amyloid species.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Cell Line; Fluores | 2010 |
Transient aggregation and stable dimerization induced by introducing an Alzheimer sequence into a water-soluble protein.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Dimeri | 2004 |
Triggers of full-length tau aggregation: a role for partially folded intermediates.
Topics: Alzheimer Disease; Anilino Naphthalenesulfonates; Circular Dichroism; Fluorescent Dyes; Humans; In V | 2005 |