Page last updated: 2024-10-21

1-anilino-8-naphthalenesulfonate and Alcoholic Cirrhosis

1-anilino-8-naphthalenesulfonate has been researched along with Alcoholic Cirrhosis in 27 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Research Excerpts

ExcerptRelevanceReference
"Nonalcoholic fatty liver disease (NAFLD) affects around a quarter of the global population, paralleling worldwide increases in obesity and metabolic syndrome."2.66Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology. ( Eslam, M; George, J, 2020)
"Pancreatic panniculitis is a rare complication characterized by subcutaneous fat necrosis associated with pancreatic disease."2.55[Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature]. ( Cho, DH; Cho, EY; Chu, MS; Kim, EJ; Kim, HC; Na, GH; Sohn, KC, 2017)
"The incidence of hepatocellular carcinoma (HCC) is increasing in Western countries."2.50Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data. ( Bontempi, G; Burza, MA; Corradini, SG; Deltenre, P; Devière, J; Donati, B; Falleti, E; Franchimont, D; Guyot, E; Hamza, S; Henrion, J; Hillon, P; Mathurin, P; Moreno, C; Nahon, P; Nischalke, HD; Romeo, S; Spengler, U; Toniutto, P; Trépo, E; Valenti, L, 2014)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's1 (3.70)18.2507
2000's0 (0.00)29.6817
2010's21 (77.78)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Nischalke, HD7
Schmalz, F2
Buch, S5
Fischer, J3
Möller, C2
Matz-Soja, M2
Krämer, B3
Langhans, B2
Klüners, A2
Soyka, M4
Stickel, F6
Nattermann, J3
Berg, T7
Strassburg, CP2
Lutz, P2
Eslam, M1
George, J1
Beaudoin, JJ1
Long, N1
Liangpunsakul, S1
Puri, P1
Kamath, PS1
Shah, V1
Sanyal, AJ1
Crabb, DW1
Chalasani, NP1
Urban, TJ1
Weiss, KH1
Gotthardt, D1
Rosendahl, J4
Marot, A1
Elamly, M1
Casper, M1
Lammert, F4
McQuillin, A2
Zopf, S2
Spengler, U4
Marhenke, S1
Kirstein, MM1
Vogel, A1
Eyer, F2
von Felden, J1
Wege, H1
Buch, T1
Schafmayer, C3
Braun, F2
Deltenre, P4
Morgan, MY2
Hampe, J3
Wang, LQ1
Guo, WH1
Guo, ZW1
Qin, P1
Zhang, R1
Zhu, XM1
Liu, DW1
Burza, MA3
Molinaro, A2
Attilia, ML1
Rotondo, C1
Attilia, F1
Ceccanti, M1
Ferri, F1
Maldarelli, F1
Maffongelli, A1
De Santis, A1
Attili, AF1
Romeo, S4
Ginanni Corradini, S1
Trépo, E4
Nahon, P3
Bontempi, G1
Valenti, L2
Falleti, E4
Hamza, S1
Corradini, SG2
Guyot, E3
Donati, B2
Hillon, P1
Toniutto, P4
Henrion, J1
Franchimont, D4
Devière, J3
Mathurin, P1
Moreno, C4
Dongiovanni, P1
Fares, R1
Lombardi, R1
Mancina, RM1
Salameh, H1
Raff, E1
Erwin, A1
Seth, D1
Leathert, J1
Ulrich, S1
Daly, A1
Day, CP2
Kuo, YF1
Singal, AK1
Way, M1
Herrmann, A1
Brosch, M1
Ridinger, M2
Rietschel, M2
Frank, J1
Kiefer, F2
Schreiber, S2
Lieb, W1
Semmo, N1
Aigner, E1
Datz, C2
Schmelz, R1
Brückner, S1
Zeissig, S1
Stephan, AM1
Wodarz, N2
Clumeck, N1
Sarrazin, C2
Gustot, T3
Völzke, H2
Lerch, MM1
Mayerle, J1
Cichon, S1
Nöthen, MM1
Nothnagel, M1
Ellinghaus, D1
Huse, K1
Franke, A1
Hellerbrand, C2
Cussigh, A2
Cmet, S2
Fabris, C2
Weber, C1
Anstee, QM1
Daly, AK1
Fjeld, K1
Beer, S1
Johnstone, M1
Zimmer, C1
Mössner, J2
Ruffert, C2
Krehan, M1
Zapf, C1
Njølstad, PR1
Johansson, S1
Bugert, P2
Miyajima, F1
Liloglou, T1
Brown, LJ1
Winn, SA1
Davies, K1
Latawiec, D1
Gunson, BK1
Criddle, DN1
Pirmohamed, M1
Grützmann, R2
Michl, P1
Greenhalf, W1
Molven, A1
Sutton, R1
Kim, EJ1
Chu, MS1
Sohn, KC1
Cho, DH1
Na, GH1
Kim, HC1
Cho, EY1
Tian, C1
Stokowski, RP1
Kershenobich, D1
Ballinger, DG1
Hinds, DA1
Lau, K1
Meyer zu Schwabedissen, H1
Hinrichsen, H1
Günther, R1
Arlt, A1
Seeger, M1
Müller, S1
Seitz, HK1
Lerch, M1
Kubitz, R1
Häussinger, D1
Bröring, D1
Spanagel, R1
Mann, K1
Krawczak, M1
Degré, D2
Lemmers, A1
Verset, L1
Demetter, P1
Ouziel, R1
Quertinmont, E1
Vercruysse, V1
Amininejad, L1
Le Moine, O1
Bitetto, D1
Fontanini, E1
Fornasiere, E1
Bignulin, S1
Fumolo, E1
Bignulin, E1
Pirisi, M1
Berger, C1
Luda, C1
Müller, T1
Grünhage, F1
Coenen, M1
Körner, C1
Vidovic, N1
Oldenburg, J1
Sauerbruch, T1
Ganne-Carrie, N2
Sutton, A2
Tönjes, A1
Schleinitz, D1
Kovacs, P1
Wiegand, J1
Jesinghaus, M1
Schober, R1
Herms, M1
Schulz, HU1
Werner, J1
Blüher, M1
Stumvoll, M1
Böhm, S1
Wittenburg, H1
te Morsche, R1
Derikx, M1
Keim, V1
Witt, H1
Drenth, JP1
Rufat, P1
Laguillier, C1
Mansouri, A1
Moreau, R1
Beaugrand, M1
Charnaux, N1
Trinchet, JC1
BAKER, SP1
LEVINE, H1
TURNER, L1
DUBIN, A1
Brailski, C1
Mendisova, A1
Glawintschewa, I1
Breier, C1
Lisch, HJ1
Braunsteiner, H1
Yuki, T1
Akagi, S1
Hirakawa, K1
Uchida, Y1
Fukuda, R1
Ashizawa, N1
Watanabe, M1
Kinoshita, Y1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Early Detection of Advanced Liver Fibrosis in Patients With Excessive Alcohol Intake[NCT04070508]0 participants (Actual)Observational [Patient Registry]2023-04-01Withdrawn (stopped due to Staff in the lab have transitioned to a new institution so there are no personnel available to recruit or resume the study.)
Study of Metabolism Influence in Human Alcoholic Liver Disease[NCT01122797]658 participants (Actual)Observational2003-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for 1-anilino-8-naphthalenesulfonate and Alcoholic Cirrhosis

ArticleYear
Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology.
    Nature reviews. Gastroenterology & hepatology, 2020, Volume: 17, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Acyltransferases; Adaptor Proteins, Signal Transducing; Carcinoma,

2020
Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:6

    Topics: Carcinoma, Hepatocellular; Hepatitis C, Chronic; Humans; Lipase; Liver Cirrhosis, Alcoholic; Liver N

2014
PNPLA3 I148M polymorphism and progressive liver disease.
    World journal of gastroenterology, 2013, Nov-07, Volume: 19, Issue:41

    Topics: Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Disease Progression; Fatty Liver; Fatty Liver, A

2013
PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease.
    The American journal of gastroenterology, 2015, Volume: 110, Issue:6

    Topics: Carcinoma, Hepatocellular; Central Nervous System Depressants; Chemical and Drug Induced Liver Injur

2015
Genetics of Alcoholic Liver Disease.
    Seminars in liver disease, 2015, Volume: 35, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Carcinoma, Hepatocellular; Disease Progression; Ethanol; Fatty Liver,

2015
[Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2017, Jan-25, Volume: 69, Issue:1

    Topics: Adult; Amylases; Erythema; Female; Humans; Laboratories; Lipase; Liver Cirrhosis, Alcoholic; Pancrea

2017

Trials

1 trial available for 1-anilino-8-naphthalenesulfonate and Alcoholic Cirrhosis

ArticleYear
Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease.
    Journal of hepatology, 2011, Volume: 55, Issue:4

    Topics: Adult; Aged; Fatty Liver, Alcoholic; Female; Genetic Predisposition to Disease; Genotype; Humans; Li

2011

Other Studies

20 other studies available for 1-anilino-8-naphthalenesulfonate and Alcoholic Cirrhosis

ArticleYear
Genetic Variation of
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho

2022
Genetic Variation of
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho

2022
Genetic Variation of
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho

2022
Genetic Variation of
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Carcinoma, Hepatocellular; Genetic Predisposition to Disease; Genotype; Humans; Lipase; Liver Cirrho

2022
An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis.
    Scandinavian journal of gastroenterology, 2017, Volume: 52, Issue:11

    Topics: Adult; Case-Control Studies; Female; Genetic Predisposition to Disease; Genome-Wide Association Stud

2017
Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis.
    The American journal of gastroenterology, 2018, Volume: 113, Issue:10

    Topics: Acyltransferases; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Disease Progression; Europe

2018
[Effects of PNPLA3, TM6SF2 gene polymorphisms and its interactions with smoking and alcohol drinking on hepatitis B virus-associated hepatocellular carcinoma].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2018, Dec-10, Volume: 39, Issue:12

    Topics: Alcohol Drinking; Carcinoma, Hepatocellular; Case-Control Studies; Epistasis, Genetic; Gene-Environm

2018
PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:4

    Topics: Adult; Age of Onset; Alcohol Drinking; Genotype; Humans; Incidence; Italy; Kaplan-Meier Estimate; Li

2014
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis.
    Nature genetics, 2015, Volume: 47, Issue:12

    Topics: Acyltransferases; Adult; Aged; Case-Control Studies; Female; Genetic Predisposition to Disease; Geno

2015
PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:1

    Topics: Carcinoma, Hepatocellular; Female; Homozygote; Humans; Lipase; Liver Cirrhosis, Alcoholic; Liver Neo

2016
Liver: New genetic insights into the development of alcohol-related cirrhosis.
    Nature reviews. Gastroenterology & hepatology, 2015, Volume: 12, Issue:12

    Topics: Acyltransferases; Female; Genome-Wide Association Study; Humans; Lipase; Liver Cirrhosis, Alcoholic;

2015
Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Exons; Female; Genetic Predisposition to Disease; G

2016
Variant in PNPLA3 is associated with alcoholic liver disease.
    Nature genetics, 2010, Volume: 42, Issue:1

    Topics: Adult; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Human

2010
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:1

    Topics: Adult; Aged; Alanine Transaminase; Alcoholism; Fatty Liver, Alcoholic; Female; Gene Frequency; Germa

2011
PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Chi-Square Distribu

2011
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Female; Genetic Pre

2011
PNPLA3 (rs738409 C>G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis.
    Hepatology (Baltimore, Md.), 2012, Volume: 55, Issue:4

    Topics: Adult; Aged; Belgium; Carcinoma, Hepatocellular; Comorbidity; Female; France; Genetic Predisposition

2012
A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Genotyp

2012
PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis.
    Journal of hepatology, 2013, Volume: 58, Issue:2

    Topics: Carcinoma, Hepatocellular; Female; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Incide

2013
Lipoprotein lipase response in Laennec's cirrhosis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 99, Issue:3

    Topics: Humans; Lipase; Lipoprotein Lipase; Liver Cirrhosis; Liver Cirrhosis, Alcoholic

1958
[Pancreatic exocrine secretion in patients with cirrhosis of the liver (author's transl)].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1981, Volume: 41, Issue:5

    Topics: Amylases; Bicarbonates; Cholecystokinin; Female; Humans; Lipase; Liver Cirrhosis; Liver Cirrhosis, A

1981
Lipoproteins, HDL-apolipoproteins, activities of hepatic lipase and lecithin-cholesterol acyltransferase in the plasma of patients with post-alcoholic end-stage liver cirrhosis.
    Klinische Wochenschrift, 1983, Sep-15, Volume: 61, Issue:18

    Topics: Adult; Aged; Apolipoproteins; Humans; Lipase; Lipoproteins; Lipoproteins, HDL; Liver; Liver Cirrhosi

1983
Simultaneous elevation of serum amylase and lipase levels due to multiclass immunoglobulin-bound enzymes in a patient with alcoholic liver cirrhosis.
    Pancreas, 1999, Volume: 18, Issue:4

    Topics: Aged; Amylases; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Lipas

1999