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1-anilino-8-naphthalenesulfonate and Abdominal Obesity

1-anilino-8-naphthalenesulfonate has been researched along with Abdominal Obesity in 10 studies

1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd
8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.

Research Excerpts

ExcerptRelevanceReference
"It is well established that combining a reduced calorie, low-fat diet with the lipase inhibitor orlistat results in significantly greater weight loss than placebo plus diet."9.15Pragmatic study of orlistat 60 mg on abdominal obesity. ( Beaver, JD; Bell, JD; Berk, ES; Delafont, B; Frost, G; Gambarota, G; Makwana, A; Matthews, PM; Mishra, RG; Newbould, R; Rao, AW; Schwartz, SM; Thomas, EL, 2011)
"It is well established that combining a reduced calorie, low-fat diet with the lipase inhibitor orlistat results in significantly greater weight loss than placebo plus diet."5.15Pragmatic study of orlistat 60 mg on abdominal obesity. ( Beaver, JD; Bell, JD; Berk, ES; Delafont, B; Frost, G; Gambarota, G; Makwana, A; Matthews, PM; Mishra, RG; Newbould, R; Rao, AW; Schwartz, SM; Thomas, EL, 2011)
"In some patients with NAFLD, isolated steatosis can progress to advanced stages with non-alcoholic steatohepatitis (NASH) and fibrosis, increasing the risk of cirrhosis and hepatocellular carcinoma."2.61Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies. ( Cusi, K; Häring, HU; Stefan, N, 2019)
"Nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are highly prevalent, affecting approximately one-third of the US population."2.58Nonalcoholic Fatty Liver Disease and Metabolic Syndrome. ( Kim, D; Kim, WR; Touros, A, 2018)
"Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes (T2D) and obesity are epidemiologically correlated with each other but the causal inter-relationships between them remain incompletely understood."1.56Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping. ( Cai, D; Chen, YE; Dong, XC; Graham, S; Huang, M; Liu, W; Liu, Z; Pique-Regi, R; Wang, X; Willer, C; Zhang, Y, 2020)
"Visceral obesity is one of the risk factors for clinically relevant pancreatic fistula after pancreatic resection."1.51Clinical and experimental studies of intraperitoneal lipolysis and the development of clinically relevant pancreatic fistula after pancreatic surgery. ( Anazawa, T; Masui, T; Nagai, K; Nakano, K; Sato, A; Tabata, Y; Takaori, K; Uchida, Y; Uemoto, S; Yogo, A, 2019)
"Liver cirrhosis is a leading cause of death in Hispanics and Hispanics who live in South Texas have the highest incidence of liver cancer in the United States."1.43Cirrhosis and Advanced Fibrosis in Hispanics in Texas: The Dominant Contribution of Central Obesity. ( Beretta, L; Fallon, MB; Fisher-Hoch, SP; Jiao, J; Lee, M; McCormick, JB; Pan, JJ; Rahbar, MH; Vatcheva, KP; Watt, GP, 2016)
"androgen deficiency) raises the risk for abdominal obesity in men."1.43Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice. ( Hanaoka, R; Harada, N; Horiuchi, H; Inui, H; Kitakaze, T; Mitani, T; Yamaji, R, 2016)
" These negative associations between clinical risk factors and rs738409-G dosage were more prominent in non-NAFLD group compared to those in NAFLD group."1.42I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease. ( Cho, B; Choi, HC; Hwang, KB; Kim, JI; Kong, SW; Kwon, H; Lee, IH; Park, JH; Prilutsky, D; Yun, JM, 2015)
"CT-defined fatty liver is common among men at risk for HIV infection and is associated with greater visceral adiposity, HOMA-IR, and PNPLA3 (rs738409)."1.40Risk factors for fatty liver in the Multicenter AIDS Cohort Study. ( Budoff, MJ; Kingsley, LA; Latanich, R; Palella, FJ; Post, WS; Price, JC; Seaberg, EC; Thio, CL; Witt, MD, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (90.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Liu, Z1
Zhang, Y1
Graham, S1
Wang, X1
Cai, D1
Huang, M1
Pique-Regi, R1
Dong, XC1
Chen, YE1
Willer, C1
Liu, W1
Kim, D1
Touros, A1
Kim, WR1
Stefan, N1
Häring, HU1
Cusi, K1
Xia, MF1
Lin, HD1
Chen, LY1
Wu, L1
Ma, H1
Li, Q1
Aleteng, Q1
Hu, Y1
He, WY1
Gao, J1
Bian, H1
Li, XY1
Gao, X1
Uchida, Y1
Masui, T1
Nakano, K1
Yogo, A1
Sato, A1
Nagai, K1
Anazawa, T1
Takaori, K1
Tabata, Y1
Uemoto, S1
Price, JC1
Seaberg, EC1
Latanich, R1
Budoff, MJ1
Kingsley, LA1
Palella, FJ1
Witt, MD1
Post, WS1
Thio, CL1
Park, JH1
Cho, B1
Kwon, H1
Prilutsky, D1
Yun, JM1
Choi, HC1
Hwang, KB1
Lee, IH1
Kim, JI1
Kong, SW1
Jiao, J1
Watt, GP1
Lee, M1
Rahbar, MH1
Vatcheva, KP1
Pan, JJ1
McCormick, JB1
Fisher-Hoch, SP1
Fallon, MB1
Beretta, L1
Harada, N1
Hanaoka, R1
Horiuchi, H1
Kitakaze, T1
Mitani, T1
Inui, H1
Yamaji, R1
Thomas, EL1
Makwana, A1
Newbould, R1
Rao, AW1
Gambarota, G1
Frost, G1
Delafont, B1
Mishra, RG1
Matthews, PM1
Berk, ES1
Schwartz, SM1
Bell, JD1
Beaver, JD1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Microbiome Reprogramming on Liver Fat Accumulation[NCT03914495]57 participants (Actual)Interventional2019-05-21Terminated (stopped due to PI carefully considered multiple factors and decided to close study to any further enrollment.)
Comparative Clinical Study to Evaluate the Possible Beneficial Effect of Empagliflozin Versus Pioglitazone on Non-diabetic Patients With Non-Alcoholic Steatohepatitis[NCT05605158]Phase 356 participants (Anticipated)Interventional2022-11-30Not yet recruiting
To Investigate the Role of Gut Microbiome in Androgen Deprivation Therapy Related Metabolic Changes in Prostate Cancer Patients[NCT04687709]50 participants (Anticipated)Observational2021-01-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for 1-anilino-8-naphthalenesulfonate and Abdominal Obesity

ArticleYear
Nonalcoholic Fatty Liver Disease and Metabolic Syndrome.
    Clinics in liver disease, 2018, Volume: 22, Issue:1

    Topics: Dyslipidemias; Humans; Hyperglycemia; Hypertension; Lipase; Membrane Proteins; Metabolic Syndrome; N

2018
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
    The lancet. Diabetes & endocrinology, 2019, Volume: 7, Issue:4

    Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit

2019
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
    The lancet. Diabetes & endocrinology, 2019, Volume: 7, Issue:4

    Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit

2019
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
    The lancet. Diabetes & endocrinology, 2019, Volume: 7, Issue:4

    Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit

2019
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.
    The lancet. Diabetes & endocrinology, 2019, Volume: 7, Issue:4

    Topics: Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Cardiovascular Diseases; Diabetes Mellit

2019

Trials

1 trial available for 1-anilino-8-naphthalenesulfonate and Abdominal Obesity

ArticleYear
Pragmatic study of orlistat 60 mg on abdominal obesity.
    European journal of clinical nutrition, 2011, Volume: 65, Issue:11

    Topics: Abdominal Fat; Adiposity; Adult; Anti-Obesity Agents; Body Mass Index; Combined Modality Therapy; Di

2011

Other Studies

7 other studies available for 1-anilino-8-naphthalenesulfonate and Abdominal Obesity

ArticleYear
Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping.
    Journal of hepatology, 2020, Volume: 73, Issue:2

    Topics: Animals; Causality; Diabetes Mellitus, Type 2; Europe; Founder Effect; Genome-Wide Association Study

2020
The PNPLA3 rs738409 C>G variant interacts with changes in body weight over time to aggravate liver steatosis, but reduces the risk of incident type 2 diabetes.
    Diabetologia, 2019, Volume: 62, Issue:4

    Topics: Adipose Tissue; Aged; Anthropometry; Blood Glucose; Body Weight; China; Diabetes Mellitus, Type 2; F

2019
Clinical and experimental studies of intraperitoneal lipolysis and the development of clinically relevant pancreatic fistula after pancreatic surgery.
    The British journal of surgery, 2019, Volume: 106, Issue:5

    Topics: Aged; Animals; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Humans; Intra-Abdominal F

2019
Risk factors for fatty liver in the Multicenter AIDS Cohort Study.
    The American journal of gastroenterology, 2014, Volume: 109, Issue:5

    Topics: Anti-HIV Agents; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Fatty Liver; Genetic

2014
I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:12

    Topics: Adult; Body Mass Index; Genetic Predisposition to Disease; Humans; Insulin Resistance; Lipase; Liver

2015
Cirrhosis and Advanced Fibrosis in Hispanics in Texas: The Dominant Contribution of Central Obesity.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Cohort Studies; Female; Hispanic or Latino; Humans; Lipase; Liver Cirrhosis; Male; Membrane Proteins

2016
Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice.
    Scientific reports, 2016, Mar-10, Volume: 6

    Topics: Adipose Tissue; Androgens; Animals; Anti-Bacterial Agents; Blood Glucose; Castration; Diet, High-Fat

2016