1-aminoindan-1,5-dicarboxylic acid has been researched along with Pain in 5 studies
1-aminoindan-1,5-dicarboxylic acid: structure given in first source
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the non-selective, 1-aminoindan-1,5-dicarboxylic acid (AIDA), and selective (3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl) methanone (JNJ16259685), metabotropic glutamate subtype 1 (mGlu1) receptor antagonists, on rat sciatic nerve chronic constrictive injury (CCI)-induced hyperalgesia, allodynia, spinal dorsal horn apoptosis, and gliosis was examined at 3 and 7 days post-injury." | 3.74 | Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats. ( de Novellis, V; Ferraraccio, F; Fuccio, C; Giordano, C; Luongo, L; Maione, S; Rossi, F; Roth, KA; Siniscalco, D, 2008) |
| "Intraspinal injection of quisqualic acid, a mixed kainic acid/2-amino-3(3-hydroxy-5-methylisoxazol-4-yl)propionic acid and metabotropic glutamate receptor agonist, produces an excitotoxic injury that leads to the onset of both spontaneous and evoked pain behavior as well as changes in spinal and cortical expression of opioid peptide mRNA, preprodynorphin and preproenkephalin." | 3.71 | The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury. ( Abraham, KE; Brewer, KL; McGinty, JF, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, K | 1 |
| Lefebvre, C | 1 |
| Coderre, TJ | 1 |
| Siniscalco, D | 1 |
| Giordano, C | 1 |
| Fuccio, C | 1 |
| Luongo, L | 1 |
| Ferraraccio, F | 1 |
| Rossi, F | 1 |
| de Novellis, V | 1 |
| Roth, KA | 1 |
| Maione, S | 1 |
| Bordi, F | 1 |
| Ugolini, A | 1 |
| Abraham, KE | 1 |
| McGinty, JF | 1 |
| Brewer, KL | 1 |
| Zhou, S | 1 |
| Komak, S | 1 |
| Du, J | 1 |
| Carlton, SM | 1 |
5 other studies available for 1-aminoindan-1,5-dicarboxylic acid and Pain
| Article | Year |
|---|---|
Antinociceptive effects following intrathecal pretreatment with selective metabotropic glutamate receptor compounds in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Constriction, Pathologic; Excitatory Amino Acid Antagonists; Indans; Injections | 2002 |
Involvement of subtype 1 metabotropic glutamate receptors in apoptosis and caspase-7 over-expression in spinal cord of neuropathic rats.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Caspase 7; Constriction, Pathol | 2008 |
Involvement of mGluR(5) on acute nociceptive transmission.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Indans; Injec | 2000 |
The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury.
Topics: Animals; Behavior, Animal; Dynorphins; Enkephalins; Excitatory Amino Acid Agonists; Excitatory Amino | 2001 |
Metabotropic glutamate 1alpha receptors on peripheral primary afferent fibers: their role in nociception.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excita | 2001 |