1-aminoindan-1,5-dicarboxylic acid has been researched along with Malaria in 2 studies
1-aminoindan-1,5-dicarboxylic acid: structure given in first source
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The orally bioavailable lead imidazolopiperazine confers complete causal prophylactic protection (15 milligrams/kilogram) in rodent models of malaria and shows potent in vivo blood-stage therapeutic activity." | 1.37 | Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. ( Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plouffe, D | 1 |
| Brinker, A | 1 |
| McNamara, C | 1 |
| Henson, K | 1 |
| Kato, N | 2 |
| Kuhen, K | 1 |
| Nagle, A | 2 |
| Adrián, F | 1 |
| Matzen, JT | 1 |
| Anderson, P | 1 |
| Nam, TG | 2 |
| Gray, NS | 1 |
| Chatterjee, A | 2 |
| Janes, J | 1 |
| Yan, SF | 1 |
| Trager, R | 1 |
| Caldwell, JS | 1 |
| Schultz, PG | 2 |
| Zhou, Y | 2 |
| Winzeler, EA | 2 |
| Meister, S | 1 |
| Plouffe, DM | 1 |
| Kuhen, KL | 1 |
| Bonamy, GM | 1 |
| Wu, T | 1 |
| Barnes, SW | 1 |
| Bopp, SE | 1 |
| Borboa, R | 1 |
| Bright, AT | 1 |
| Che, J | 1 |
| Cohen, S | 1 |
| Dharia, NV | 1 |
| Gagaring, K | 1 |
| Gettayacamin, M | 1 |
| Gordon, P | 1 |
| Groessl, T | 1 |
| Lee, MC | 1 |
| McNamara, CW | 1 |
| Fidock, DA | 1 |
| Richmond, W | 1 |
| Roland, J | 1 |
| Rottmann, M | 1 |
| Zhou, B | 1 |
| Froissard, P | 1 |
| Glynne, RJ | 1 |
| Mazier, D | 1 |
| Sattabongkot, J | 1 |
| Tuntland, T | 1 |
| Walker, JR | 1 |
| Diagana, TT | 1 |
2 other studies available for 1-aminoindan-1,5-dicarboxylic acid and Malaria
| Article | Year |
|---|---|
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug | 2008 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resista | 2011 |