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1-aminoindan-1,5-dicarboxylic acid and Brain Ischemia

1-aminoindan-1,5-dicarboxylic acid has been researched along with Brain Ischemia in 2 studies

1-aminoindan-1,5-dicarboxylic acid: structure given in first source

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
" To elucidate the role of group I mGluR, we tested the effects of (S)-alpha-methyl-4-carboxy-phenylglycine (MCPG, mGluR 1 and 5 antagonist), 1-aminoindan-1,5-dicarboxylic acid (AIDA, mGluR 1a specific antagonist) and 2-methyl-6-(phenylethynyl) pyridine (MPEP, mGluR 5 antagonist) on ArAc release and neuronal survival after transient forebrain ischemia in gerbils."3.70Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil. ( Dempsey, RJ; Hatcher, JF; Rao, AM, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meli, E1
Picca, R1
Attucci, S1
Cozzi, A1
Peruginelli, F1
Moroni, F1
Pellegrini-Giampietro, DE1
Rao, AM1
Hatcher, JF1
Dempsey, RJ1

Other Studies

2 other studies available for 1-aminoindan-1,5-dicarboxylic acid and Brain Ischemia

ArticleYear
Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:2

    Topics: Animals; Brain Ischemia; Bridged Bicyclo Compounds; Cell Line; Cricetinae; Excitatory Amino Acid Ago

2002
Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil.
    Neuroscience letters, 2000, Oct-20, Volume: 293, Issue:1

    Topics: Animals; Arachidonic Acid; Benzoates; Brain; Brain Ischemia; Cell Survival; Excitatory Amino Acid An

2000