1-aminoindan-1,5-dicarboxylic acid has been researched along with Brain Ischemia in 2 studies
1-aminoindan-1,5-dicarboxylic acid: structure given in first source
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To elucidate the role of group I mGluR, we tested the effects of (S)-alpha-methyl-4-carboxy-phenylglycine (MCPG, mGluR 1 and 5 antagonist), 1-aminoindan-1,5-dicarboxylic acid (AIDA, mGluR 1a specific antagonist) and 2-methyl-6-(phenylethynyl) pyridine (MPEP, mGluR 5 antagonist) on ArAc release and neuronal survival after transient forebrain ischemia in gerbils." | 3.70 | Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil. ( Dempsey, RJ; Hatcher, JF; Rao, AM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meli, E | 1 |
| Picca, R | 1 |
| Attucci, S | 1 |
| Cozzi, A | 1 |
| Peruginelli, F | 1 |
| Moroni, F | 1 |
| Pellegrini-Giampietro, DE | 1 |
| Rao, AM | 1 |
| Hatcher, JF | 1 |
| Dempsey, RJ | 1 |
2 other studies available for 1-aminoindan-1,5-dicarboxylic acid and Brain Ischemia
| Article | Year |
|---|---|
Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo.
Topics: Animals; Brain Ischemia; Bridged Bicyclo Compounds; Cell Line; Cricetinae; Excitatory Amino Acid Ago | 2002 |
Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil.
Topics: Animals; Arachidonic Acid; Benzoates; Brain; Brain Ischemia; Cell Survival; Excitatory Amino Acid An | 2000 |