1-aminoindan-1,5-dicarboxylic acid has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
1-aminoindan-1,5-dicarboxylic acid: structure given in first source
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The possible toxic factor(s) and the exact mode of action (e." | 1.33 | Protective effect of metabotropic glutamate receptor inhibition on amyotrophic lateral sclerosis-cerebrospinal fluid toxicity in vitro. ( Anneser, JM; Borasio, GD; Chahli, C, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anneser, JM | 1 |
| Chahli, C | 1 |
| Borasio, GD | 1 |
1 other study available for 1-aminoindan-1,5-dicarboxylic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Protective effect of metabotropic glutamate receptor inhibition on amyotrophic lateral sclerosis-cerebrospinal fluid toxicity in vitro.
Topics: Aged; Amyotrophic Lateral Sclerosis; Animals; Cell Count; Cell Death; Cells, Cultured; Cerebrospinal | 2006 |