1-alpha-24-dihydroxyvitamin-d3 and Vitamin-D-Deficiency

1-alpha-24-dihydroxyvitamin-d3 has been researched along with Vitamin-D-Deficiency* in 2 studies

Other Studies

2 other study(ies) available for 1-alpha-24-dihydroxyvitamin-d3 and Vitamin-D-Deficiency

Article	Year
Hailey-Hailey disease successfully treated with vitamin D oral supplementation. Dermatologic therapy, 2019, Volume: 32, Issue:1 Hailey-Hailey disease (HHD) also known as familial benign chronic pemphigus is a rare autosomal dominant genodermatosis. HHD treatment is often not satisfactory and hence, various modalities of treatment have been tried. We describe the case of a 37-year-old woman with a 2 years history of macerated erythematous plaques along with erosions, fissures, and crusts located on axillae and submammary areas, successfully treated with only oral supplementation of vitamin D (800 I.U./die) for 3 months. We reported this case to suggest that oral vitamin D may be enumerated in the various treatments proposed for HHD so far due to its rapid efficacy on skin lesions and symptoms. Topics: Administration, Cutaneous; Administration, Oral; Adult; Biopsy; Dietary Supplements; Dihydroxycholecalciferols; Female; Humans; Ointments; Pemphigus, Benign Familial; Remission Induction; Skin; Time Factors; Treatment Outcome; Vitamin D; Vitamin D Deficiency	2019
Effect of 1 alpha, 24(R)-dihydroxyvitamin D3 on calcium metabolism in the rat. Acta endocrinologica, 1986, Volume: 111, Issue:4 It has been suggested that 1 alpha, 24(R)-dihydroxyvitamin D3 (1,24(OH)2D3), a chemically synthesized vitamin D analogue, may have the property to enhance whole-body Ca retention and may thus be of use in osteoporosis. In order to test this hypothesis the main fluxes of Ca metabolism were measured in vitamin D-replete rats injected ip with 1.24(OH)2D3 at daily doses of 25, 50 and 100 pmol for 10 days. As compared with pair fed control animals, rats treated with 1,24(OH)2D3 displayed a significant rise in net intestinal absorption of Ca and in urinary excretion of Ca, and increase in bone resorption but no significant change in bone formation. Whole body Ca retention was not changed at 25 pmol/day and showed a trend to decrease at 50 and 100 pmol/day. In conclusion these results do not suggest that among available vitamin D analogues, 1,24(OH)2D3 would be particularly useful for increasing bone Ca retention in osteoporosis. Topics: Animals; Bone Development; Bone Resorption; Calcium; Dihydroxycholecalciferols; Dose-Response Relationship, Drug; Female; Intestinal Absorption; Rats; Rats, Inbred Strains; Vitamin D Deficiency	1986

Article

Year

Hailey-Hailey disease successfully treated with vitamin D oral supplementation.

Dermatologic therapy, 2019, Volume: 32, Issue:1

Hailey-Hailey disease (HHD) also known as familial benign chronic pemphigus is a rare autosomal dominant genodermatosis. HHD treatment is often not satisfactory and hence, various modalities of treatment have been tried. We describe the case of a 37-year-old woman with a 2 years history of macerated erythematous plaques along with erosions, fissures, and crusts located on axillae and submammary areas, successfully treated with only oral supplementation of vitamin D (800 I.U./die) for 3 months. We reported this case to suggest that oral vitamin D may be enumerated in the various treatments proposed for HHD so far due to its rapid efficacy on skin lesions and symptoms.

Topics: Administration, Cutaneous; Administration, Oral; Adult; Biopsy; Dietary Supplements; Dihydroxycholecalciferols; Female; Humans; Ointments; Pemphigus, Benign Familial; Remission Induction; Skin; Time Factors; Treatment Outcome; Vitamin D; Vitamin D Deficiency

2019

Effect of 1 alpha, 24(R)-dihydroxyvitamin D3 on calcium metabolism in the rat.

Acta endocrinologica, 1986, Volume: 111, Issue:4

It has been suggested that 1 alpha, 24(R)-dihydroxyvitamin D3 (1,24(OH)2D3), a chemically synthesized vitamin D analogue, may have the property to enhance whole-body Ca retention and may thus be of use in osteoporosis. In order to test this hypothesis the main fluxes of Ca metabolism were measured in vitamin D-replete rats injected ip with 1.24(OH)2D3 at daily doses of 25, 50 and 100 pmol for 10 days. As compared with pair fed control animals, rats treated with 1,24(OH)2D3 displayed a significant rise in net intestinal absorption of Ca and in urinary excretion of Ca, and increase in bone resorption but no significant change in bone formation. Whole body Ca retention was not changed at 25 pmol/day and showed a trend to decrease at 50 and 100 pmol/day. In conclusion these results do not suggest that among available vitamin D analogues, 1,24(OH)2D3 would be particularly useful for increasing bone Ca retention in osteoporosis.

Topics: Animals; Bone Development; Bone Resorption; Calcium; Dihydroxycholecalciferols; Dose-Response Relationship, Drug; Female; Intestinal Absorption; Rats; Rats, Inbred Strains; Vitamin D Deficiency

1986