1-alpha-24-dihydroxyvitamin-d3 and Leg-Dermatoses

1-alpha-24-dihydroxyvitamin-d3 has been researched along with Leg-Dermatoses* in 1 studies

Other Studies

1 other study(ies) available for 1-alpha-24-dihydroxyvitamin-d3 and Leg-Dermatoses

Article	Year
Hyperkeratosis lenticularis perstans (Flegel's disease)--lack of response to treatment with tacalcitol and calcipotriol. Dermatology (Basel, Switzerland), 2001, Volume: 202, Issue:3 Hyperkeratosis lenticularis perstans (HLP) or Flegel's disease is a rare dermatosis characterized by asymptomatic hyperkeratotic papules predominantly located on the lower extremities. Lesional and non-lesional epidermis samples were studied by light- and electron-microscopic examination. The main ultrastructural finding was the presence of structurally altered Odland bodies/membrane-coating granules. Different therapeutic options for HLP have been reported, but none of the treatments was shown to be consistently effective. Here, we report on a patient with Flegel's disease who did respond to topical 5-fluorouracil, whereas topical vitamin D(3) synthetics were ineffective. Topics: Calcitriol; Dermatologic Agents; Dihydroxycholecalciferols; Female; Humans; Keratosis; Leg Dermatoses; Microscopy, Electron; Middle Aged; Skin; Treatment Outcome	2001

Article

Year

Hyperkeratosis lenticularis perstans (Flegel's disease)--lack of response to treatment with tacalcitol and calcipotriol.

Dermatology (Basel, Switzerland), 2001, Volume: 202, Issue:3

Hyperkeratosis lenticularis perstans (HLP) or Flegel's disease is a rare dermatosis characterized by asymptomatic hyperkeratotic papules predominantly located on the lower extremities. Lesional and non-lesional epidermis samples were studied by light- and electron-microscopic examination. The main ultrastructural finding was the presence of structurally altered Odland bodies/membrane-coating granules. Different therapeutic options for HLP have been reported, but none of the treatments was shown to be consistently effective. Here, we report on a patient with Flegel's disease who did respond to topical 5-fluorouracil, whereas topical vitamin D(3) synthetics were ineffective.

Topics: Calcitriol; Dermatologic Agents; Dihydroxycholecalciferols; Female; Humans; Keratosis; Leg Dermatoses; Microscopy, Electron; Middle Aged; Skin; Treatment Outcome

2001