Page last updated: 2024-08-24

1,7-phenanthroline and Cancer of Liver

1,7-phenanthroline has been researched along with Cancer of Liver in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's6 (26.09)18.2507
2000's3 (13.04)29.6817
2010's9 (39.13)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Chen, M; Fan, L; Liu, Y; Liu, Z; Niu, D; Wang, D; Xu, J; Zhang, W1
Chen, Q; Liu, H; Lu, D; Pang, X; Qiu, Y; Wang, K; Wang, R; Wang, T; Yang, S; Yin, S; Yu, H; Zhang, Y1
Cai, Y; He, Y; Liang, S; Liu, J; Xu, N; Zhang, C; Zhang, D; Zhang, P; Zhu, H1
Cao, JQ; Liu, HM; Mei, WJ; Song, Y; Wang, X; Wang, XC; Wu, Q1
Li, L; Liu, HM; Mei, WJ; Song, Y; Wang, XC; Wu, Q; Zhang, H; Zhang, SY1
Garin, E; Lepareur, N; Lopez, A; Noiret, N1
Furukawa, A; Harada, K; Hiraku, Y; Kawanishi, S; Murata, M; Oikawa, S; Shimada, A; Sugiyama, H1
Huang, HL; Li, ZZ; Liang, ZH; Liu, YJ; Yao, JH3
Bandyopadhyay, D; Banik, BK; Granados, JC; Mukherjee, S; Short, JD1
Cai, X; Pan, N; Zou, G1
Chen, X; Xia, R1
Kodama, A; Matsuzaki, S; Tsuda, M; Tsuda, TT; Yamamura, M1
Band, CJ; Contreres, JO; Dumas, V; Posner, BI1
Morgan, E; Trinder, D1
Fujii, J; Gutteridge, JM; Inoue, T; Koizumi, M; Suzuki, K; Taniguchi, N1
Gong, J; Tao, D; Zheng, C; Zhou, H; Zou, G1
Hosoda, S; Nakamura, W; Takatsuki, K1
Allen, MS; Crawford, IL; Jacob, ST; Rose, KM1
Brown, WE; Czupryn, M; Vallee, BL1
Fagan, JB; Pasco, DS; Perry, DJ; Saatcioglu, F1
Brada, Z; Bulba, S1

Other Studies

23 other study(ies) available for 1,7-phenanthroline and Cancer of Liver

ArticleYear
The copper (II) complex of salicylate phenanthroline inhibits proliferation and induces apoptosis of hepatocellular carcinoma cells.
    Environmental toxicology, 2023, Volume: 38, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Copper; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Phenanthrolines; Proto-Oncogene Proteins c-bcl-2; Salicylates; Survivin

2023
HTBPI, an active phenanthroindolizidine alkaloid, inhibits liver tumorigenesis by targeting Akt.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:9

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Female; Humans; Indolizines; Liver Neoplasms; Male; Mice; Phenanthrolines; Proto-Oncogene Proteins c-akt

2020
In vitro anticancer effects of two novel phenanthroindolizidine alkaloid compounds on human colon and liver cancer cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:3

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; HCT116 Cells; Hep G2 Cells; HT29 Cells; Humans; Indolizines; Liver Neoplasms; Phenanthrolines

2017
A phenanthroline derivative enhances radiosensitivity of hepatocellular carcinoma cells by inducing mitochondria-dependent apoptosis.
    European journal of pharmacology, 2019, Jan-15, Volume: 843

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Mitochondria; Phenanthrolines; Radiation Tolerance; Radiation-Sensitizing Agents; X-Rays

2019
Phenanthroimidazole derivatives act as potentinducer of autophagy by activating DNA damage pathway.
    Bioorganic chemistry, 2019, Volume: 88

    Topics: Animals; Antineoplastic Agents; Autophagy; Cell Cycle; Cell Proliferation; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Imidazoles; Liver Neoplasms; Liver Neoplasms, Experimental; Phenanthrolines; Tumor Cells, Cultured; Zebrafish

2019
Mixed-ligand complexes of yttrium-90 dialkyldithiocarbamates with 1,10-phenanthroline as a possible agent for therapy of hepatocellular carcinoma.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 94

    Topics: Carcinoma, Hepatocellular; Drug Stability; Ethiodized Oil; Feasibility Studies; Humans; Isotope Labeling; Liver Neoplasms; Materials Testing; Phenanthrolines; Radiopharmaceuticals; Thiocarbamates; Treatment Outcome; Yttrium Radioisotopes

2014
Oxidatively generated DNA damage induced by 3-amino-5-mercapto-1,2,4-triazole, a metabolite of carcinogenic amitrole.
    Mutation research, 2010, Dec-10, Volume: 694, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amitrole; Carcinogens; Chelating Agents; Copper; Cyclin-Dependent Kinase Inhibitor p16; Deoxyguanosine; DNA Damage; Humans; Liver Neoplasms; Neoplasm Proteins; Oxygen; Phenanthrolines; ras Proteins; Sodium Azide; Thyroid Neoplasms; Triazoles; Tumor Suppressor Protein p53

2010
Ruthenium(II) polypyridyl complexes: synthesis and studies of DNA binding, photocleavage, cytotoxicity, apoptosis, cellular uptake, and antioxidant activity.
    DNA and cell biology, 2011, Volume: 30, Issue:10

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA; Electrophoretic Mobility Shift Assay; Female; Fluorescence; Humans; Hydroxyl Radical; Intercalating Agents; Kinetics; Liver Neoplasms; Organometallic Compounds; Oxidation-Reduction; Phenanthrolines; Photolysis; Plasmids; Ruthenium; Spectrum Analysis; Ultraviolet Rays

2011
Cytotoxicity, apoptosis, cellular uptake, cell cycle arrest, photocleavage, and antioxidant activity of 1, 10-phenanthroline ruthenium(II) complexes.
    DNA and cell biology, 2011, Volume: 30, Issue:10

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA; Electrophoretic Mobility Shift Assay; Female; Flow Cytometry; Fluorescence; Humans; Hydroxyl Radical; Intercalating Agents; Kinetics; Liver Neoplasms; Organometallic Compounds; Oxidation-Reduction; Phenanthrolines; Photolysis; Plasmids; Ruthenium; Spectrum Analysis; Ultraviolet Rays

2011
Synthesis, cellular uptake, apopotosis, cytotoxicity, cell cycle arrest, interaction with DNA and antioxidant activity of ruthenium(II) complexes.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Coordination Complexes; Differential Thermal Analysis; DNA; DNA Cleavage; Electrophoretic Mobility Shift Assay; Flow Cytometry; Humans; Intercalating Agents; Ligands; Liver Neoplasms; Phenanthrolines; Plasmids; Ruthenium

2011
Ultrasound-assisted bismuth nitrate-induced green synthesis of novel pyrrole derivatives and their biological evaluation as anticancer agents.
    European journal of medicinal chemistry, 2012, Volume: 50

    Topics: Animals; Antineoplastic Agents; Bismuth; Cell Survival; Cells, Cultured; HeLa Cells; Hep G2 Cells; Hepatocytes; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; NIH 3T3 Cells; Nitrates; Phenanthrolines; Pyrroles; Quantitative Structure-Activity Relationship; Ultrasonics

2012
Copper-1,10-phenanthroline-induced apoptosis in liver carcinoma Bel-7402 cells associates with copper overload, reactive oxygen species production, glutathione depletion and oxidative DNA damage.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2007, Volume: 20, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Comet Assay; Copper; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione; Humans; Liver Neoplasms; Organometallic Compounds; Phenanthrolines; Reactive Oxygen Species; Time Factors

2007
Effects of Danshen injection on the malignant obstructive jaundice in the SD rat model.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2006, Volume: 26, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Drugs, Chinese Herbal; Intercellular Adhesion Molecule-1; Jaundice, Obstructive; Liver; Liver Neoplasms; Male; Neoplasm Metastasis; Phenanthrolines; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Salvia miltiorrhiza; Vascular Endothelial Growth Factor A

2006
Isolation and characterization of a high molecular weight type IV collagenase isolated from human carcinoma tissue.
    FEBS letters, 1993, Mar-15, Volume: 319, Issue:1-2

    Topics: Collagen; Collagenases; Edetic Acid; Enzyme Activation; Gelatin; Gelatinases; Glycoproteins; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Matrix Metalloproteinase 9; Metalloendopeptidases; Molecular Weight; Pepsin A; Phenanthrolines; Substrate Specificity; Tissue Inhibitor of Metalloproteinases; Trypsin

1993
Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).
    Molecular endocrinology (Baltimore, Md.), 1997, Volume: 11, Issue:13

    Topics: Animals; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Organometallic Compounds; Phenanthrolines; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Rats; Receptor, Insulin; Recombinant Fusion Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Substrate Specificity; Tumor Cells, Cultured; Tyrosine

1997
Mechanisms of ferric citrate uptake by human hepatoma cells.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: 2,2'-Dipyridyl; Binding Sites; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Membrane; Chelating Agents; Ferric Compounds; Humans; Iron; Iron Radioisotopes; Kinetics; Liver Neoplasms; Phenanthrolines; Time Factors; Tumor Cells, Cultured

1998
A marked increase in free copper levels in the plasma and liver of LEC rats: an animal model for Wilson disease and liver cancer.
    Free radical research, 1998, Volume: 28, Issue:5

    Topics: Animals; Bleomycin; Ceruloplasmin; Copper; Disease Models, Animal; Hepatolenticular Degeneration; Iron; Liver; Liver Neoplasms; Phenanthrolines; Rats

1998
G(1)-phase specific apoptosis in liver carcinoma cell line induced by copper-1,10-phenanthroline.
    The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:6

    Topics: Annexin A5; Apoptosis; Carcinoma; DNA; DNA Fragmentation; G1 Phase; Humans; Liver Neoplasms; Organometallic Compounds; Phenanthrolines; Sensitivity and Specificity; Time Factors; Tumor Cells, Cultured

2002
Properties of tryptophan hydroxylase from human carcinoid tumor.
    Biochimica et biophysica acta, 1977, May-12, Volume: 482, Issue:1

    Topics: Aged; Humans; Hydrogen-Ion Concentration; Iron; Kinetics; Liver Neoplasms; Male; Malignant Carcinoid Syndrome; Mercaptoethanol; Mixed Function Oxygenases; Neoplasm Metastasis; Oxygen; Phenanthrolines; Tryptophan Hydroxylase

1977
Functional role of zinc in poly(A) synthesis catalyzed by nuclear poly(A) polymerase.
    European journal of biochemistry, 1978, Jul-17, Volume: 88, Issue:1

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Dithiothreitol; Edetic Acid; Liver; Liver Neoplasms; Neoplasms, Experimental; Nucleotidyltransferases; Phenanthrolines; Poly A; Polynucleotide Adenylyltransferase; Protein Binding; Rats; Zinc

1978
Zinc rapidly induces a metal response element-binding factor.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-01, Volume: 89, Issue:21

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Nucleus; DNA Probes; DNA-Binding Proteins; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lung Neoplasms; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Oligonucleotide Probes; Phenanthrolines; Sulfates; Tumor Cells, Cultured; Zinc; Zinc Sulfate

1992
Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 gene.
    Molecular and cellular biology, 1990, Volume: 10, Issue:12

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Copper; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Genes; Humans; Liver Neoplasms; Molecular Sequence Data; Nucleotide Mapping; Oligonucleotide Probes; Phenanthrolines; Plasmids; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Receptors, Aryl Hydrocarbon; Receptors, Drug; Transcription, Genetic; Transfection

1990
Influence of 1,10-phenanthroline on liver tumorigenesis in rats ingesting ethionine.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 3, Issue:2

    Topics: Animals; Body Weight; Ethionine; Female; Liver; Liver Neoplasms; Neoplasms, Experimental; Organ Size; Phenanthrolines; Rats; Rats, Inbred Strains

1972