Page last updated: 2024-08-24

1,7-phenanthroline and Breast Cancer

1,7-phenanthroline has been researched along with Breast Cancer in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.34)18.2507
2000's4 (13.79)29.6817
2010's18 (62.07)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Marković, SD; Milivojević, NN; Milutinović, MG; Nikodijević, DD; Radisavljević, SR; Đeković Kesić, AS; Đorđević, NM1
Fang, J; Northcote-Smith, J; Ortu, F; Osei, PB; Singh, K; Suntharalingam, K1
Cooke, G; Creaven, BS; Devereux, M; Enyedy, ÉA; Howe, O; Jenkins, H; MacLean, L; May, NV; McClean, S; Pereira, MD1
Brabec, V; Kasparkova, J; Kostrhunova, H; Markova, L; Novohradsky, V; Trávníček, Z1
Bonizzoni, M; Brown, SR; Cameron, CG; DeRegnaucourt, AR; Gray, JL; Hall, JF; Kim, Y; Lamb, RW; McFarland, SA; Oladipupo, OE; Papish, ET; Petersen, CM; Qu, F; Shrestha, AB; Thompson, MK; Ward, NA; Webster, CE; Xu, Y1
Al-Khdhairawi, AAQ; Chong, KW; Chung, FF; Kam, TS; Krishnan, P; Leong, CO; Lim, KH; Low, YY; Mai, CW; Yong, KT1
Bineva-Todd, G; Eskandari, A; Laws, K; Lu, C; O'Reilly, N; Suntharalingam, K1
Fahmidehkar, MA; Falahati-Pour, SK; Hajizadeh, MR; Khoshdel, A; Mahmoodi, M; Mirzaei, MR; Mohamadi, M; Mohammadizadeh, F; Rezaei, A1
Alves, LN; DE Almeida, CEB; Lage, CAS; Missailidis, S1
Morvan, D1
Chen, Y; Wu, DM; Wu, L1
Chen, CH; Gong, C; Guo, W; Hu, H; Huang, P; Lee, DY; Lieberman, J; Lu, KP; Luo, ML; Reinhardt, F; Song, E; Wulf, G; Yao, Y; Zhou, XZ1
Assad, LO; Casey, A; Colleran, J; Creaven, B; Dempsey, R; Devereux, M; Dixit, V; Howe, O; Kellett, A; Kia, AF; McCann, M; McClean, S; O'Shea, D; Pereira, MD; Queiroz, DD; Ribeiro, TP; Rochford, G; Thornton, L; Walsh, M1
Mei, WJ; Sun, FY; Wu, Q; Zeng, ZP; Zheng, KD1
Bi, C; Fan, Y; Sun, S; Wang, H; Wang, Q; Yan, M; Zhang, Z1
Cha, YN; Chung, JH; Kim, DH; Kim, EH; Kim, JH; Na, HK; Surh, YJ1
Han, X; Jeon, MJ; Ju, JH; Shin, I; Yang, W1
Bi, C; Chen, DI; Cui, Q; Dou, QP; Fan, Y; Xiao, Y; Zhang, X1
Almeida, J; Bandarra, D; Brandão, P; Calhorda, MJ; Félix, V; Lopes, M; Lopes, T; Meireles, M; Nunes, CD; Saraiva, MS; Vasconcellos-Dias, M; Vaz, PD1
Huang, HL; Li, ZZ; Liang, ZH; Liu, YJ; Yao, JH2
Ahmad, M; Chin, LF; Khoo, KS; Khoo, SB; Kong, SM; Maah, MJ; Ng, CH; Seng, HL; Teoh, SG; Vikneswaran, R1
Akbarsha, MA; Arunachalam, S; Dinesh, M; Krishnamurthy, H; Kumar, RS; Paul, CP; Riyasdeen, A; Srinag, S1
Moses, MA; Pories, SE; Roy, R; Wewer, UM; Zurakowski, D1
Berger, W; Chiba, P; Dornetshuber, R; Elbling, L; Heffeter, P; Jakupec, MA; Keppler, BK; Körner, W; Micksche, M; Pirker, C; Sutterlüty, H1
Patel, KV; Schrey, MP1
Burkley, M; Dinda, S; Hurd, C; Kodali-Gali, S; Moudgil, VK; Sevilla, L1
Chopra, S; Wallace, HM1
Hara, Y; Iwase, H; Iwase, T; Iwata, H; Kobayashi, S; Miura, S; Mizutani, M; Nemori, R; Obata, Y; Omoto, Y; Toyama, T; Yamamoto, M; Yamashita, H1

Other Studies

29 other study(ies) available for 1,7-phenanthroline and Breast Cancer

ArticleYear
Gold(III) Complexes with Phenanthroline-derivatives Ligands Induce Apoptosis in Human Colorectal and Breast Cancer Cell Lines.
    Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:12

    Topics: Apoptosis; Breast Neoplasms; Caspase 9; Cell Line, Tumor; Colorectal Neoplasms; Female; Gold; Humans; Ligands; Phenanthrolines; Proto-Oncogene Proteins c-bcl-2

2022
The Bulk Breast Cancer Cell and Breast Cancer Stem Cell Activity of Binuclear Copper(II)-Phenanthroline Complexes.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2023, Aug-10, Volume: 29, Issue:45

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chlorides; Cisplatin; Coordination Complexes; Copper; Female; Humans; Ligands; Neoplastic Stem Cells; Phenanthrolines

2023
Structural and solution speciation studies on selected [Cu(NN)(OO)] complexes and an investigation of their biomimetic activity, ROS generation and their cytotoxicity in normoxic, hypoxic and anoxic environments in MCF-7 breast cancer-derived cells.
    Journal of inorganic biochemistry, 2023, Volume: 249

    Topics: Antineoplastic Agents; Biomimetics; Breast Neoplasms; Coordination Complexes; Copper; Female; Humans; MCF-7 Cells; Phenanthrolines; Reactive Oxygen Species; Superoxide Dismutase

2023
An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis.
    Scientific reports, 2019, 09-16, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chloroacetates; Coordination Complexes; Cymenes; Female; Humans; Necroptosis; Necrosis; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Organoplatinum Compounds; Osmium; Phenanthrolines; Tumor Microenvironment

2019
Light-responsive and Protic Ruthenium Compounds Bearing Bathophenanthroline and Dihydroxybipyridine Ligands Achieve Nanomolar Toxicity towards Breast Cancer Cells.
    Photochemistry and photobiology, 2022, Volume: 98, Issue:1

    Topics: Breast Neoplasms; Female; Humans; Ligands; Phenanthrolines; Ruthenium; Ruthenium Compounds

2022
A Bis-benzopyrroloisoquinoline Alkaloid Incorporating a Cyclobutane Core and a Chlorophenanthroindolizidine Alkaloid with Cytotoxic Activity from Ficus fistulosa var. tengerensis.
    Journal of natural products, 2017, 10-27, Volume: 80, Issue:10

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Crystallography, X-Ray; Cyclobutanes; Ficus; Heterocyclic Compounds, 4 or More Rings; Humans; Indolizines; Inhibitory Concentration 50; Isoquinolines; Malaysia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenanthrolines; Plant Leaves; Stereoisomerism

2017
A Copper(II) Phenanthroline Metallopeptide That Targets and Disrupts Mitochondrial Function in Breast Cancer Stem Cells.
    Angewandte Chemie (International ed. in English), 2018, 01-02, Volume: 57, Issue:1

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coordination Complexes; Female; Humans; Inhibitory Concentration 50; MAP Kinase Kinase 4; Metalloproteins; Mitochondria; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Peptides; Phenanthrolines; Pyrans; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2018
The cytotoxicity effects of a novel Cu complex on MCF-7 human breast cancerous cells.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2018, Volume: 31, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Coordination Complexes; Copper; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; MCF-7 Cells; Phenanthrolines

2018
Anti-MUC1 Aptamer as Carrier Tool of the Potential Radiosensitizer 1,10 Phenanthroline in MCF-7 Breast Cancer Cells.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Aptamers, Nucleotide; Breast Neoplasms; Drug Carriers; Endocytosis; Feasibility Studies; Female; Ferrous Compounds; Humans; MCF-7 Cells; Mucin-1; Phenanthrolines; Radiation-Sensitizing Agents

2019
Functional metabolomics uncovers metabolic alterations associated to severe oxidative stress in MCF7 breast cancer cells exposed to ascididemin.
    Marine drugs, 2013, Oct-11, Volume: 11, Issue:10

    Topics: Alkaloids; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Humans; MCF-7 Cells; Metabolome; Metabolomics; Oxidative Stress; Phenanthrolines; Quinolines

2013
[Preparation and anti-breast cancer activity of (-)-antofine carried with liposomes].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Carriers; Drug Compounding; Drug Stability; Female; Humans; Indoles; Liposomes; MCF-7 Cells; Mice; Mice, Nude; Nanoparticles; Particle Size; Phenanthrolines; Solubility; Xenograft Model Antitumor Assays

2013
Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancer.
    Cancer research, 2014, Jul-01, Volume: 74, Issue:13

    Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplastic Stem Cells; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phenanthrolines; RNA Interference; Transduction, Genetic; Tumor Cells, Cultured

2014
Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity.
    Journal of inorganic biochemistry, 2016, Volume: 159

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Breast Neoplasms; Candida albicans; Female; Humans; Intercalating Agents; MCF-7 Cells; Ovarian Neoplasms; Phenanthrolines; Saccharomyces cerevisiae; Silver; Solubility

2016
Imaging Nuclei of MDA-MB-231 Breast Cancer Cells by Chiral Ruthenium(II) Complex Coordinated by 2-(4-Phenyacetylenephenyl)-1H-imidazo[4,5f][1,10]phenanthroline.
    Inorganic chemistry, 2016, Jun-06, Volume: 55, Issue:11

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Coordination Complexes; Humans; Phenanthrolines; Ruthenium Compounds; Spectrum Analysis; Stereoisomerism; Zebrafish

2016
Anticancer activity and computational modeling of ternary copper (II) complexes with 3-indolecarboxylic acid and 1,10-phenanthroline.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Copper; Female; Humans; Indoles; Phenanthrolines; Proteasome Inhibitors

2016
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
    Carcinogenesis, 2009, Volume: 30, Issue:4

    Topics: Breast Neoplasms; Cell Movement; Heme Oxygenase-1; Humans; Immunologic Factors; Iron; Iron Chelating Agents; Luciferases; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; NF-E2-Related Factor 2; Phenanthrolines; Prostaglandin D2; Protoporphyrins; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Up-Regulation; Wound Healing

2009
Danshen (Salvia miltiorrhiza) extract inhibits proliferation of breast cancer cells via modulation of Akt activity and p27 level.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:2

    Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Drugs, Chinese Herbal; Female; Humans; Phenanthrolines; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Salvia miltiorrhiza

2010
Molecular study on copper-mediated tumor proteasome inhibition and cell death.
    International journal of oncology, 2010, Volume: 37, Issue:1

    Topics: Breast Neoplasms; Cell Death; Chelating Agents; Copper; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Leukemia; Neoplasms; Phenanthrolines; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured

2010
Mo(II) complexes: a new family of cytotoxic agents?
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:11

    Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Molybdenum; Neoplasms; Neuroblastoma; Nucleic Acid Conformation; Phenanthrolines; Tetrazolium Salts; Thiazoles; Water

2010
Ruthenium(II) polypyridyl complexes: synthesis and studies of DNA binding, photocleavage, cytotoxicity, apoptosis, cellular uptake, and antioxidant activity.
    DNA and cell biology, 2011, Volume: 30, Issue:10

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA; Electrophoretic Mobility Shift Assay; Female; Fluorescence; Humans; Hydroxyl Radical; Intercalating Agents; Kinetics; Liver Neoplasms; Organometallic Compounds; Oxidation-Reduction; Phenanthrolines; Photolysis; Plasmids; Ruthenium; Spectrum Analysis; Ultraviolet Rays

2011
Synthesis, characterization and biological properties of cobalt(II) complexes of 1,10-phenanthroline and maltol.
    Journal of inorganic biochemistry, 2011, Volume: 105, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chelating Agents; Cobalt; Crystallography, X-Ray; DNA; DNA Topoisomerases, Type I; Female; Humans; Inhibitory Concentration 50; Ligands; Organometallic Compounds; Phenanthrolines; Pyrones; Spectrum Analysis

2011
Cytotoxicity, apoptosis, cellular uptake, cell cycle arrest, photocleavage, and antioxidant activity of 1, 10-phenanthroline ruthenium(II) complexes.
    DNA and cell biology, 2011, Volume: 30, Issue:10

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA; Electrophoretic Mobility Shift Assay; Female; Flow Cytometry; Fluorescence; Humans; Hydroxyl Radical; Intercalating Agents; Kinetics; Liver Neoplasms; Organometallic Compounds; Oxidation-Reduction; Phenanthrolines; Photolysis; Plasmids; Ruthenium; Spectrum Analysis; Ultraviolet Rays

2011
Cytotoxic property of surfactant-cobalt(III) complexes on a human breast cancer cell line.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:7

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cobalt; Comet Assay; DNA Damage; Female; Humans; Membrane Potential, Mitochondrial; Phenanthrolines; Staining and Labeling; Surface-Active Agents

2011
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: ADAM Proteins; ADAM12 Protein; Adult; Aged; Amino Acid Sequence; Animals; Blotting, Western; Breast Neoplasms; Caseins; Catalysis; Chelating Agents; Chromatography, Affinity; Chromatography, Ion Exchange; Collagen Type I; Collagen Type IV; COS Cells; Databases as Topic; Densitometry; Disease Progression; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Extracellular Matrix; Female; Fibronectins; Gelatin; Humans; Hydroxamic Acids; Immunoblotting; Membrane Proteins; Metalloendopeptidases; Middle Aged; Molecular Sequence Data; Neoplasm Metastasis; Peptides; Phenanthrolines; Plasmids; Recombinant Proteins; Sensitivity and Specificity; Sepharose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Ultracentrifugation; Zinc

2004
Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24).
    Biochemical pharmacology, 2007, Jun-15, Volume: 73, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Carcinoma, Small Cell; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Formazans; HL-60 Cells; Humans; Lanthanum; Lung Neoplasms; Molecular Structure; Neoplasm Proteins; Organic Anion Transporters; Organometallic Compounds; Phenanthrolines; Sensitivity and Specificity; Tetrazolium Salts

2007
Human breast cancer cells contain a phosphoramidon-sensitive metalloproteinase which can process exogenous big endothelin-1 to endothelin-1: a proposed mitogen for human breast fibroblasts.
    British journal of cancer, 1995, Volume: 71, Issue:3

    Topics: Aspartic Acid Endopeptidases; Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Culture Media; Edetic Acid; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Fibroblasts; Glycopeptides; Growth Substances; Humans; Hydrogen-Ion Concentration; Iron Chelating Agents; Kinetics; Metalloendopeptidases; Mitogens; Phenanthrolines; Protease Inhibitors; Protein Precursors; Sensitivity and Specificity; Tumor Cells, Cultured

1995
Inhibition of proliferation of T47D human breast cancer cells: alterations in progesterone receptor and p53 tumor suppressor protein.
    Molecular and cellular biochemistry, 1997, Volume: 175, Issue:1-2

    Topics: Antineoplastic Agents; Aurintricarboxylic Acid; Blotting, Western; Breast Neoplasms; Cell Division; DNA-Binding Proteins; Down-Regulation; Drug Screening Assays, Antitumor; Electrophoresis, Polyacrylamide Gel; Humans; Neoplasms, Hormone-Dependent; Phenanthrolines; Progesterone Congeners; Promegestone; Receptors, Progesterone; Rifampin; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1997
Induction of spermidine/spermine N1-acetyltransferase in human cancer cells in response to increased production of reactive oxygen species.
    Biochemical pharmacology, 1998, Apr-01, Volume: 55, Issue:7

    Topics: Acetyltransferases; Breast Neoplasms; Free Radical Scavengers; Free Radicals; Humans; Hyperoxia; Iron Chelating Agents; Phenanthrolines; Reactive Oxygen Species; Thiourea; Tumor Cells, Cultured

1998
Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography.
    Breast cancer (Tokyo, Japan), 2001, Volume: 8, Issue:2

    Topics: Azo Compounds; Breast Neoplasms; Cell Nucleus; Enzyme Inhibitors; Gelatin; Gelatinases; Hematoxylin; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Phenanthrolines; Sensitivity and Specificity; Staining and Labeling

2001