Page last updated: 2024-08-24

1,7-phenanthroline and Alzheimer Disease

1,7-phenanthroline has been researched along with Alzheimer Disease in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's5 (25.00)29.6817
2010's12 (60.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Drommi, M; Esmieu, C; Hureau, C; Rulmont, C1
Anisha, M; Gladis, EHE; Joseph, J; Nagashri, K1
Bulova, P; Christian, BT; Devenny, D; Handen, BL; Hardison, R; Hartley, SL; Johnson, SC; Klunk, WE; Lao, PJ; Mihaila, I1
Abe, T; Ataka, S; Hasegawa, I; Itoh, Y; Kawabe, J; Kikukawa, T; Mino, T; Saito, H; Takeuchi, J; Wada, Y; Watanabe, Y1
Basha, HM; Boopathy, R; Chitra, L; Kumar, CR; Ponne, S1
Fan, Q; Lang, M; Wang, L; Wang, W; Wang, X; Xiao, G; Zheng, Y; Zhong, Y; Zhou, B1
Barnham, KJ; Caine, JM; Chandana Epa, V; Churches, QI; James, SA; Kenche, VB; Streltsov, VA1
Bhat, SS; Jani, V; Joshi, B; Joshi, RR; Kulkarni, PP; Kumbhar, AS; Ramteke, SN; Sonawane, UB; Vyas, NA1
Corby, P; Craig, RG; de Leon, MJ; Glodzik, L; Kamer, AR; Linker, R; McHugh, P; Mosconi, L; Pirraglia, E; Rusinek, H; Saxena, D; Shi, C; Svetcov, S; Tsui, W; Vallabhajosula, S; Williams, S; Yi, L1
Bottelbergs, A; Kelley, JB; Langlois, X; Schmidt, ME; Staelens, S; Stroobants, S; Waldron, AM; Wintmolders, C1
Arcisio-Miranda, M; Cali, MP; Carlos, RM; Carlos-Lima, E; Ito, AS; Pazin, WM; Salles Trevisan, MT; Silva, DE; Venâncio, T1
Raymick, J; Schmued, L1
Ishii, K1
Huang, F; Jia, L; Jiang, T; Li, L; Liu, Y; Ma, G; Pu, X1
Barnham, KJ; Bush, AI; Cherny, RA; Masters, CL; Yao, S1
Boldron, C; Deraeve, C; Gornitzka, H; Meunier, B; Pitié, M; Van der Auwera, I; Van Leuven, F; Wera, S1
Barnham, KJ; Caragounis, A; Cherny, RA; Crouch, PJ; Drew, SC; Du, T; Filiz, G; Hill, AF; Laughton, KM; Li, QX; Masters, CL; Sharples, RA; Volitakis, I; White, AR1
Atwood, CS; Beyreuther, K; Bush, AI; Cherny, RA; Fairlie, DP; Huang, X; Legg, JT; Masters, CL; McLean, CA; Tanzi, RE1
Barnham, KJ; Beyreuther, K; Bush, AI; Cherny, RA; Li, QX; Lynch, T; Masters, CL; McLean, CA; Multhaup, G; Tanzi, RE; Volitakis, I1
Eckman, C; Golde, T; Musunuru, U; Onstead, L; Pinnix, I; Sambamurti, K; Sridharan, A; Tun, H; Ziani-Cherif, C1

Reviews

1 review(s) available for 1,7-phenanthroline and Alzheimer Disease

ArticleYear
[Amyloid PET in Alzheimer research].
    Brain and nerve = Shinkei kenkyu no shinpo, 2010, Volume: 62, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Carbon Radioisotopes; Humans; Phenanthrolines; Positron-Emission Tomography; Radiopharmaceuticals; Rhombencephalon; Thiazoles

2010

Other Studies

19 other study(ies) available for 1,7-phenanthroline and Alzheimer Disease

ArticleYear
Hybrid Bis-Histidine Phenanthroline-Based Ligands to Lessen Aβ-Bound Cu ROS Production: An Illustration of Cu(I) Significance.
    Molecules (Basel, Switzerland), 2021, Dec-16, Volume: 26, Issue:24

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Copper; Histidine; Humans; Phenanthrolines; Reactive Oxygen Species

2021
Synthesis, characterisation, DNA binding, acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities and molecular docking studies of metal(II) complexes with 1,10-phenanthroline scaffold.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:11

    Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Coordination Complexes; Humans; Metals; Molecular Docking Simulation; Molecular Structure; Phenanthrolines; Structure-Activity Relationship

2023
Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome.
    Neurobiology of aging, 2017, Volume: 58

    Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Cognition; Cognitive Dysfunction; Down Syndrome; Executive Function; Female; Humans; Male; Memory, Episodic; Middle Aged; Phenanthrolines; Positron-Emission Tomography; Thiazoles; Time Factors

2017
Amyloid deposition and CBF patterns predict conversion of mild cognitive impairment to dementia.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2018, Volume: 39, Issue:9

    Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Brain; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; Humans; Male; Neuropsychological Tests; Perfusion Imaging; Phenanthrolines; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies; Thiazoles; Tomography, Emission-Computed, Single-Photon

2018
Interaction of metal chelators with different molecular forms of acetylcholinesterase and its significance in Alzheimer's disease treatment.
    Proteins, 2013, Volume: 81, Issue:7

    Topics: Acetylcholinesterase; Alzheimer Disease; Amidohydrolases; Amyloid beta-Peptides; Chelating Agents; Cholinesterase Inhibitors; Esterases; Humans; Hydrophobic and Hydrophilic Interactions; Metals; Molecular Dynamics Simulation; Phenanthrolines

2013
Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms.
    Neurobiology of aging, 2013, Volume: 34, Issue:11

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Cation Transport Proteins; Cell Count; Chelating Agents; Conditioning, Classical; Copper Transporter 1; Disease Models, Animal; Drosophila; Drosophila Proteins; Gene Expression Regulation; Humans; Locomotion; Longevity; Male; Memory Disorders; Nerve Degeneration; Nervous System; Oxidative Stress; Peptide Fragments; Phenanthrolines; RNA Interference; Time Factors

2013
Structural insights into the interaction of platinum-based inhibitors with the Alzheimer's disease amyloid-β peptide.
    Chemical communications (Cambridge, England), 2013, Dec-18, Volume: 49, Issue:97

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Coordination Complexes; Humans; Light; Phenanthrolines; Platinum; Protein Binding; Scattering, Radiation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2013
Ruthenium(II) polypyridyl complex as inhibitor of acetylcholinesterase and Aβ aggregation.
    European journal of medicinal chemistry, 2014, Mar-21, Volume: 75

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cholinesterase Inhibitors; Coordination Complexes; Humans; Organometallic Compounds; Phenanthrolines; Pyridines; Ruthenium

2014
Periodontal disease associates with higher brain amyloid load in normal elderly.
    Neurobiology of aging, 2015, Volume: 36, Issue:2

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Carbon Radioisotopes; Female; Humans; Male; Middle Aged; Periodontal Diseases; Phenanthrolines; Positron-Emission Tomography; Radiopharmaceuticals; Regression Analysis; Thiazoles

2015
In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice.
    Alzheimer's research & therapy, 2015, Dec-15, Volume: 7, Issue:1

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Autoradiography; Brain; Brain Mapping; Carbon Radioisotopes; Ethylene Glycols; Female; Fluorodeoxyglucose F18; Glucose; Humans; Immunohistochemistry; Mice, Inbred C57BL; Mice, Transgenic; Phenanthrolines; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles

2015
Luminescent Ru(II) Phenanthroline Complexes as a Probe for Real-Time Imaging of Aβ Self-Aggregation and Therapeutic Applications in Alzheimer's Disease.
    Journal of medicinal chemistry, 2016, 10-13, Volume: 59, Issue:19

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line; Cholinesterase Inhibitors; Electrophorus; Humans; Luminescent Agents; Mice; Optical Imaging; Phenanthrolines; Protein Aggregates; Ruthenium

2016
Introducing Euro-Glo, a rare earth metal chelate with numerous applications for the fluorescent localization of myelin and amyloid plaques in brain tissue sections.
    Journal of neuroscience methods, 2017, 03-01, Volume: 279

    Topics: Alzheimer Disease; Animals; Brain; Chelating Agents; Coordination Complexes; Disease Models, Animal; Fluoresceins; Fluorescent Dyes; Kainic Acid; Mice, Transgenic; Myelin Sheath; Phenanthrolines; Phosphates; Plaque, Amyloid; Rats, Sprague-Dawley; Staining and Labeling

2017
Identification of [PtCl2(phen)] binding modes in amyloid-β peptide and the mechanism of aggregation inhibition.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Oct-04, Volume: 17, Issue:41

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Binding Sites; Chromatography, High Pressure Liquid; Copper; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Organoplatinum Compounds; Phenanthrolines; Platinum; Protein Binding; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Characterizing bathocuproine self-association and subsequent binding to Alzheimer's disease amyloid beta-peptide by NMR.
    Journal of peptide science : an official publication of the European Peptide Society, 2004, Volume: 10, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Peptide Fragments; Phenanthrolines

2004
Preparation of cyclo-phen-type ligands: chelators of metal ions as potential therapeutic agents in the treatment of neurodegenerative diseases.
    Chembiochem : a European journal of chemical biology, 2005, Volume: 6, Issue:11

    Topics: Alzheimer Disease; Animals; Chelating Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Ions; Ligands; Macrocyclic Compounds; Metals; Mice; Mice, Transgenic; Molecular Structure; Neurodegenerative Diseases; Phenanthrolines; Plaque, Amyloid

2005
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
    The Biochemical journal, 2007, Nov-01, Volume: 407, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biological Transport, Active; CHO Cells; Copper; Cricetinae; Cricetulus; Humans; Ligands; Oxyquinoline; Peptides; Phenanthrolines; Zinc

2007
Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.
    The Journal of biological chemistry, 1999, Aug-13, Volume: 274, Issue:33

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Chelating Agents; Copper; Egtazic Acid; Ethylenediamines; Humans; Phenanthrolines; Water; Zinc

1999
Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease.
    Journal of structural biology, 2000, Volume: 130, Issue:2-3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Chelating Agents; Copper; Humans; Mice; Mice, Transgenic; Nuclear Magnetic Resonance, Biomolecular; Penicillamine; Peptides; Phenanthrolines; Pilot Projects; Solubility; Trientine; Zinc

2000
A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor.
    The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Caspase 3; Caspases; Cells, Cultured; Detergents; Endopeptidases; Guinea Pigs; Hydrogen-Ion Concentration; Membrane Proteins; Molecular Weight; Pepstatins; Peptide Fragments; Phenanthrolines; Protease Inhibitors; Protein Processing, Post-Translational; Solubility; Subcellular Fractions

2001