1,7-dimethylxanthine has been researched along with Malaria in 2 studies
1,7-dimethylxanthine : A dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine-containing beverages are generally consumed by Nigerians suffering from malaria and kwashiorkor in the belief that caffeine aids early recovery from these illnesses, which are common in the tropics." | 9.09 | The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor. ( Akinyinka, OO; Honeywell, R; Renwick, AG; Sowunmi, A, 2000) |
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 7.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| "Caffeine-containing beverages are generally consumed by Nigerians suffering from malaria and kwashiorkor in the belief that caffeine aids early recovery from these illnesses, which are common in the tropics." | 5.09 | The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor. ( Akinyinka, OO; Honeywell, R; Renwick, AG; Sowunmi, A, 2000) |
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 3.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kokwaro, GO | 1 |
| Szwandt, IS | 1 |
| Glazier, AP | 1 |
| Ward, SA | 1 |
| Edwards, G | 1 |
| Akinyinka, OO | 1 |
| Sowunmi, A | 1 |
| Honeywell, R | 1 |
| Renwick, AG | 1 |
1 trial available for 1,7-dimethylxanthine and Malaria
| Article | Year |
|---|---|
The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor.
Topics: Administration, Oral; Caffeine; Child; Child, Preschool; Cytochrome P-450 CYP1A2; Female; Half-Life; | 2000 |
1 other study available for 1,7-dimethylxanthine and Malaria
| Article | Year |
|---|---|
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male; | 1993 |