1,7-dimethylxanthine has been researched along with Malaria, Falciparum in 2 studies
1,7-dimethylxanthine : A dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A single oral dose of 300 mg caffeine was given to ten healthy adult Nigerians and ten adults suffering from acute uncomplicated Plasmodium falciparum malaria infection." | 5.09 | The effects of acute falciparum malaria on the disposition of caffeine and the comparison of saliva and plasma-derived pharmacokinetic parameters in adult Nigerians. ( Akinyinka, OO; Honeywell, R; Renwick, AG; Sowunmi, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, ME | 1 |
| Parrott, EE | 1 |
| Singh, R | 1 |
| Nelson, SW | 1 |
| Akinyinka, OO | 1 |
| Sowunmi, A | 1 |
| Honeywell, R | 1 |
| Renwick, AG | 1 |
1 trial available for 1,7-dimethylxanthine and Malaria, Falciparum
| Article | Year |
|---|---|
The effects of acute falciparum malaria on the disposition of caffeine and the comparison of saliva and plasma-derived pharmacokinetic parameters in adult Nigerians.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Animals; Caffeine; Child; Cytochrome P-450 C | 2000 |
1 other study available for 1,7-dimethylxanthine and Malaria, Falciparum
| Article | Year |
|---|---|
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle | 2014 |