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1,7-dimethylxanthine and Liver Dysfunction

1,7-dimethylxanthine has been researched along with Liver Dysfunction in 4 studies

1,7-dimethylxanthine : A dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals.

Research Excerpts

ExcerptRelevanceReference
"Mephenytoin metabolism was significantly decreased in both patients with mild liver disease (Child-Pugh score of 5/6) (-63% [95% confidence interval (CI), -86% to -40%]; P = ."2.72Liver disease selectively modulates cytochrome P450--mediated metabolism. ( Branch, RA; Chaves-Gnecco, D; Frye, RF; Matzke, GR; Rabinovitz, M; Shaikh, OS; Zgheib, NK, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kukongviriyapan, V1
Senggunprai, L1
Prawan, A1
Gaysornsiri, D1
Kukongviriyapan, U1
Aiemsa-Ard, J1
Frye, RF1
Zgheib, NK1
Matzke, GR1
Chaves-Gnecco, D1
Rabinovitz, M1
Shaikh, OS1
Branch, RA1
Zysset, T1
Wahlländer, A2
Preisig, R1
Renner, E1
Karlaganis, G1

Trials

2 trials available for 1,7-dimethylxanthine and Liver Dysfunction

ArticleYear
Salivary caffeine metabolic ratio in alcohol-dependent subjects.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:2

    Topics: Alcoholism; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrom

2004
Liver disease selectively modulates cytochrome P450--mediated metabolism.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

    Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studie

2006

Other Studies

2 other studies available for 1,7-dimethylxanthine and Liver Dysfunction

ArticleYear
Evaluation of caffeine plasma levels by an automated enzyme immunoassay (EMIT) in comparison with a high-performance liquid chromatographic method.
    Therapeutic drug monitoring, 1984, Volume: 6, Issue:3

    Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Liver Diseases; Rea

1984
High-performance liquid chromatographic determination of dimethylxanthine metabolites of caffeine in human plasma.
    Journal of chromatography, 1985, Mar-22, Volume: 338, Issue:2

    Topics: Ammonium Sulfate; Caffeine; Chromatography, High Pressure Liquid; Humans; Liver Diseases; Theobromin

1985