Compounds > 1,7-dimethylxanthine
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1,7-dimethylxanthine and Infections, Plasmodium

1,7-dimethylxanthine has been researched along with Infections, Plasmodium in 2 studies

1,7-dimethylxanthine : A dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals.

Research Excerpts

ExcerptRelevanceReference
"Caffeine-containing beverages are generally consumed by Nigerians suffering from malaria and kwashiorkor in the belief that caffeine aids early recovery from these illnesses, which are common in the tropics."9.09The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor. ( Akinyinka, OO; Honeywell, R; Renwick, AG; Sowunmi, A, 2000)
" The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)."7.68Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993)
"Caffeine-containing beverages are generally consumed by Nigerians suffering from malaria and kwashiorkor in the belief that caffeine aids early recovery from these illnesses, which are common in the tropics."5.09The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor. ( Akinyinka, OO; Honeywell, R; Renwick, AG; Sowunmi, A, 2000)
" The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)."3.68Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kokwaro, GO1
Szwandt, IS1
Glazier, AP1
Ward, SA1
Edwards, G1
Akinyinka, OO1
Sowunmi, A1
Honeywell, R1
Renwick, AG1

Trials

1 trial available for 1,7-dimethylxanthine and Infections, Plasmodium

ArticleYear
The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor.
    European journal of clinical pharmacology, 2000, Volume: 56, Issue:2

    Topics: Administration, Oral; Caffeine; Child; Child, Preschool; Cytochrome P-450 CYP1A2; Female; Half-Life;

2000

Other Studies

1 other study available for 1,7-dimethylxanthine and Infections, Plasmodium

ArticleYear
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:12

    Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male;

1993