1,6-hexamethylene diisocyanate and Diseases, Occupational

1,6-hexamethylene diisocyanate has been researched along with Diseases, Occupational in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (30.77)	18.7374
1990's	9 (23.08)	18.2507
2000's	15 (38.46)	29.6817
2010's	3 (7.69)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Doekes, G; Heederik, D; Jonaid, BS; Pronk, A	1
Dragos, M; Gautrin, D; Ghezzo, H; Jones, M; Malo, JL	1
Bernstein, DI; Boulet, LP; Cartier, A; Gautrin, D; Johnson, VJ; Khurana Hershey, G; Kissling, GE; Langmeyer, S; Lummus, ZL; Luster, MI; Malo, JL; Quirce, S; Sastre, J; Tarlo, SM; Yucesoy, B	1
Bieler, G; Danuser, B; Huynh, CK; Steiner, UC; Thorn, D; Tomicic, C; Yawalkar, N	1
Coren, BA; Cullen, MR; Holm, CT; Redlich, CA; Stowe, MH; Wisnewski, AV	1
Cuesta, J; De Las Heras, M; Fernández-Nieto, M; Novalbos, A; Quirce, S; Sastre, J	1
Liu, Q; Wisnewski, AV	1
Bottomly, K; Chen, L; Herrick, CA; Liu, Q; Redlich, CA; Wisnewski, AV	1
Malo, JL	1
Johnson, VJ; Luster, MI; Matheson, JM	1
Liu, J; Liu, Q; Redlich, CA; Wisnewski, AV	1
Bernstein, DI; Graham, C; Lummus, Z; Ott, MG; Woolhiser, M	1
Bernstein, DI; Boulet, LP; Campo, P; Cartier, A; Lummus, Z; Malo, JL; Wisnewski, AV	1
Doekes, G; Heederik, D; Jonkers, IC; Lammers, JW; Preller, L; Pronk, A; Raulf-Heimsoth, M; Wisnewski, AV; Wouters, IM	1
Bernstein, IL; Chen, SE	1
Bernstein, IL; Chen, SE; Splansky, GL; Vinegar, A	1
Baur, X	1
Butcher, BT	1
Cartier, A; Levitz, D; Malo, JL; Ouimet, G; Zeiss, CR	1
Laitinen, J; Muittari, A; Sovijärvi, A	1
Cockcroft, DW	1
Alarie, Y; Karol, MH	1
Cartier, A; Cloutier, Y; Grammer, LC; Lesage, J; Malo, JL; Perreault, G; Shaughnessy, MA; Vandenplas, O	1
Baur, X; Marczynski, B; Marek, W; Mensing, T; Riedel, F; Viso, N	1
Colvin, MS; Gouws, E; Lalloo, UG; Randolph, BW	1
Cullen, MR; Graham, C; Holm, CT; Homer, RJ; Karol, MH; Redlich, CA; Wirth, JA	1
Alam, R; Bernstein, DI; Bernstein, JA; Lummus, ZL	1
Ducatman, AM; Franklin, E; Franklin, PJ; Goldenberg, WS	1
Dalene, M; Littorin, M; Rylander, L; Skarping, G; Skerfving, S; Strömberg, U; Welinder, H	1
Fukushima, C; Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, S	1
Appiah-Pippim, J; Chung, JS; Cullen, MR; Eisen, EA; Gore, R; Holm, CT; Karol, MH; Lemus, R; Liu, Y; Redlich, CA; Sparer, J; Stowe, MH; Wisnewski, AV; Woskie, SR	1
Aida, H; Kimula, Y; Miura, H; Nakayama, M; Takayama, S; Usui, Y	1
Eberle, ME; Harris, KE; Nugent, KM; Patterson, R	1
Cartier, A; Grammer, LC; Harris, KE; Malo, JL; Patterson, R	1
Alexandersson, R; Hedenstierna, G; Plato, N; Tornling, G	1
Belin, L; Wass, U	1
Belin, L; Seldén, AI; Wass, U	1
Cartier, A; Ghezzo, H; Grammer, L; Harris, K; Lagier, F; Malo, JL; Patterson, R	1
Eggum, P; Grammer, LC; Liotta, JL; Patterson, R; Shaughnessy, MA; Silverstein, M	1

Reviews

2 review(s) available for 1,6-hexamethylene diisocyanate and Diseases, Occupational

Article	Year
Recent developments in diisocyanate asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5 Suppl 2 Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate	2003
Animal models for diisocyanate asthma: answers for lingering questions. Current opinion in allergy and clinical immunology, 2004, Volume: 4, Issue:2 Topics: Air Pollutants, Occupational; Allergens; Animals; Asthma; Cyanates; Humans; Isocyanates; Occupational Diseases	2004

Article

Year

Recent developments in diisocyanate asthma.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5 Suppl 2

Topics: Asthma; Cyanates; Epithelial Cells; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Isocyanates; Lung; Occupational Diseases; Occupational Exposure; Skin; Toluene 2,4-Diisocyanate

2003

Animal models for diisocyanate asthma: answers for lingering questions.

Current opinion in allergy and clinical immunology, 2004, Volume: 4, Issue:2

Topics: Air Pollutants, Occupational; Allergens; Animals; Asthma; Cyanates; Humans; Isocyanates; Occupational Diseases

2004

Other Studies

37 other study(ies) available for 1,6-hexamethylene diisocyanate and Diseases, Occupational

Article	Year
Exhaled nitric oxide in spray painters exposed to isocyanates: effect modification by atopy and smoking. Occupational and environmental medicine, 2014, Volume: 71, Issue:6 Topics: Adult; Asthma; Biomarkers; Conjunctivitis; Cross-Sectional Studies; Exhalation; Female; Humans; Hypersensitivity, Immediate; Immunoglobulins; Inflammation; Isocyanates; Male; Middle Aged; Nitric Oxide; Occupational Diseases; Occupational Exposure; Paint; Rhinitis; Smoking	2014
Specific antibodies to diisocyanate and work-related respiratory symptoms in apprentice car-painters. Occupational and environmental medicine, 2009, Volume: 66, Issue:4 Topics: Adolescent; Adult; Air Pollutants, Occupational; Antibodies, Anti-Idiotypic; Automobiles; Canada; Cohort Studies; Cyanates; Female; Humans; Immunoglobulin E; Immunoglobulin G; Inservice Training; Isocyanates; Male; Occupational Diseases; Occupational Exposure; Paint; Prospective Studies; Respiratory Tract Diseases; Surveys and Questionnaires; Young Adult	2009
Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor α. The Journal of allergy and clinical immunology, 2011, Volume: 128, Issue:2 Topics: Asthma; Case-Control Studies; Cyanates; Female; Humans; Interleukin-13; Interleukin-4 Receptor alpha Subunit; Isocyanates; Lipopolysaccharide Receptors; Male; Occupational Diseases; Occupational Exposure; Polymorphism, Single Nucleotide; Time Factors	2011
Acute life-threatening extrinsic allergic alveolitis in a paint controller. Occupational medicine (Oxford, England), 2011, Volume: 61, Issue:6 Topics: Adult; Air Pollutants, Occupational; Alveolitis, Extrinsic Allergic; Cyanates; Diagnosis, Differential; Female; Humans; Isocyanates; Occupational Diseases; Occupational Exposure; Paint	2011
Diisocyanate-exposed auto body shop workers: a one-year follow-up. American journal of industrial medicine, 2002, Volume: 42, Issue:6 Topics: Adult; Aged; Air Pollutants, Occupational; Analysis of Variance; Asthma; Automobiles; Chi-Square Distribution; Cross-Sectional Studies; Cyanates; Female; Follow-Up Studies; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Paint; Prevalence	2002
Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge. Chest, 2003, Volume: 123, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cyanates; False Negative Reactions; Female; Forced Expiratory Volume; Humans; Isocyanates; Male; Middle Aged; Monitoring, Physiologic; Occupational Diseases; Prospective Studies; Toluene 2,4-Diisocyanate	2003
Human gamma/delta T-cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate. The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:3 Topics: Allergens; Amino Acid Sequence; Asthma; Cell Division; Cell Line; Cyanates; Genes, T-Cell Receptor delta; Genetic Variation; Humans; Interferon-gamma; Isocyanates; Molecular Sequence Data; Occupational Diseases; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets	2003
'Daily pattern' of an asthmatic reaction due to isocyanates. Allergy, 2004, Volume: 59, Issue:2 Topics: Adult; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Male; Occupational Diseases	2004
Glutathione protects human airway proteins and epithelial cells from isocyanates. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:3 Topics: Air Pollutants, Occupational; Asthma; Cell Line; Cyanates; Epithelial Cells; Glutathione; Humans; Hypersensitivity; Isocyanates; Occupational Diseases; Respiratory Mucosa	2005
Evaluation of antibody binding to diisocyanate protein conjugates in a general population. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:3 Topics: Adolescent; Adult; Antibody Specificity; Cyanates; Environmental Exposure; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Prevalence; Toluene 2,4-Diisocyanate	2006
Diisocyanate conjugate and immunoassay characteristics influence detection of specific antibodies in HDI-exposed workers. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:7 Topics: Adult; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Cyanates; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoassay; Immunoglobulin E; Immunoglobulin G; Inhalation Exposure; Isocyanates; Male; Middle Aged; Molecular Structure; Observer Variation; Occupational Diseases; Predictive Value of Tests; Quality Control; Quebec; Radioallergosorbent Test; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Serum Albumin; Skin Tests	2007
Respiratory symptoms, sensitization, and exposure response relationships in spray painters exposed to isocyanates. American journal of respiratory and critical care medicine, 2007, Dec-01, Volume: 176, Issue:11 Topics: Adult; Aerosols; Air Pollutants, Occupational; Asthma; Chest Pain; Cyanates; Female; Humans; Immunoglobulin E; Immunoglobulin G; Inhalation Exposure; Isocyanates; Male; Middle Aged; Occupational Diseases; Paint; Prevalence; Pulmonary Disease, Chronic Obstructive; Respiration Disorders; Respiratory Hypersensitivity	2007
The guinea pig model of diisocyanate sensitization. I. Immunologic studies. The Journal of allergy and clinical immunology, 1982, Volume: 70, Issue:5 Topics: Animals; Asthma; Cross Reactions; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Humans; Immunization; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Passive Cutaneous Anaphylaxis; Serum Albumin; Toluene 2,4-Diisocyanate; Transferrin	1982
The guinea pig model of diisocyanate sensitization. II. Physiologic studies. The Journal of allergy and clinical immunology, 1982, Volume: 70, Issue:5 Topics: Animals; Asthma; Cyanates; Disease Models, Animal; Female; Guinea Pigs; Immune Sera; Immunoglobulin E; Isocyanates; Occupational Diseases; Respiratory Function Tests; Toluene 2,4-Diisocyanate; Transferrin	1982
Immunologic cross-reactivity between different albumin-bound isocyanates. The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:2 Topics: Adult; Aerosols; Asthma; Cyanates; Drug Hypersensitivity; Humans; Isocyanates; Middle Aged; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Skin Tests; Toluene 2,4-Diisocyanate	1983
Isocyanate induced asthma. European journal of respiratory diseases. Supplement, 1982, Volume: 123 Topics: Asthma; Bronchial Provocation Tests; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1982
Combined alveolitis and asthma due to hexamethylene diisocyanate (HDI), with demonstration of crossed respiratory and immunologic reactivities to diphenylmethane diisocyanate (MDI). The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:4 Topics: Alveolitis, Extrinsic Allergic; Asthma; Binding Sites, Antibody; Bronchial Provocation Tests; Cross Reactions; Cyanates; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Paint; Respiratory Function Tests	1983
[Diisocyanate-induced asthma and alveolitis]. Duodecim; laaketieteellinen aikakauskirja, 1984, Volume: 100, Issue:4 Topics: Adult; Alveolitis, Extrinsic Allergic; Asthma; Construction Materials; Cyanates; Humans; Isocyanates; Male; Occupational Diseases; Paint; Respiratory Function Tests	1984
Acquired persistent increase in nonspecific bronchial, reactivity associated with isocyanate exposure. Annals of allergy, 1982, Volume: 48, Issue:2 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cyanates; Forced Expiratory Volume; Histamine; Humans; Isocyanates; Male; Occupational Diseases	1982
Serologic assays for antibodies to hexamethylene diisocyanate and diphenylmethane diisocyanate. Archives of dermatology, 1981, Volume: 117, Issue:8 Topics: Antibodies; Benzhydryl Compounds; Cyanates; Humans; Isocyanates; Occupational Diseases	1981
Prepolymers of hexamethylene diisocyanate as a cause of occupational asthma. The Journal of allergy and clinical immunology, 1993, Volume: 91, Issue:4 Topics: Adult; Asthma; Bronchial Provocation Tests; Cyanates; Female; Humans; Immunoglobulin E; Isocyanates; Male; Middle Aged; Occupational Diseases; Polymers	1993
Hexamethylene diisocyanate induction of transient airway hyperresponsiveness in guinea pigs. Respiration; international review of thoracic diseases, 1997, Volume: 64, Issue:1 Topics: Acetylcholine; Administration, Inhalation; Aerosols; Animals; Bronchial Hyperreactivity; Cyanates; Disease Models, Animal; Dose-Response Relationship, Drug; Follow-Up Studies; Guinea Pigs; Hemodynamics; Isocyanates; Lung Diseases, Obstructive; Maximum Allowable Concentration; Occupational Diseases; Remission, Spontaneous; Respiratory Function Tests	1997
An evaluation of the respiratory health status of automotive spray-painters exposed to paints containing hexamethylene di-isocyanates in the greater Durban area. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1997, Volume: 87, Issue:3 Topics: Adult; Cross-Sectional Studies; Cyanates; Forced Expiratory Volume; Humans; Isocyanates; Middle Aged; Occupational Diseases; Paint; Respiratory Tract Diseases; Vital Capacity	1997
Airway isocyanate-adducts in asthma induced by exposure to hexamethylene diisocyanate. Scandinavian journal of work, environment & health, 1997, Volume: 23, Issue:3 Topics: Adult; Air Pollutants, Occupational; Asthma; Biopsy; Bronchi; Cyanates; Epithelium; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Occupational Exposure	1997
Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma. The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:2 Topics: Adult; Antigens; Asthma; Biomarkers, Tumor; Chemokine CCL2; Chemokines; Cyanates; Female; Humans; Interleukin-8; Isocyanates; Leukocytes, Mononuclear; Lymphokines; Male; Middle Aged; Occupational Diseases; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha; Tumor Protein, Translationally-Controlled 1	1998
Too hot to handle: an unusual exposure of HDI in specialty painters. American journal of industrial medicine, 2000, Volume: 37, Issue:4 Topics: Adult; Air Pollutants, Occupational; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cost of Illness; Cross-Linking Reagents; Cyanates; Dermatitis, Contact; Dyspnea; Exanthema; Follow-Up Studies; Hot Temperature; Humans; Isocyanates; Male; Methacholine Chloride; Occupational Diseases; Occupational Exposure; Paint; Spirometry; Volatilization	2000
Exposure biomarkers and risk from gluing and heating of polyurethane: a cross sectional study of respiratory symptoms. Occupational and environmental medicine, 2000, Volume: 57, Issue:6 Topics: Adhesives; Adult; Biomarkers; Cross-Sectional Studies; Cyanates; Female; Humans; Immunoglobulin G; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Polyurethanes; Respiration Disorders; Risk Assessment	2000
Hexamethylene diisocyanate causes contraction of canine tracheal smooth muscles through activation of muscarinic receptors. International archives of allergy and immunology, 2000, Volume: 123, Issue:2 Topics: Acetylcholine; Air Pollutants; Animals; Asthma; Atropine; Cyanates; Dogs; Dose-Response Relationship, Drug; Isocyanates; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Occupational Diseases; Receptors, Muscarinic; Trachea	2000
Subclinical immunologic and physiologic responses in hexamethylene diisocyanate-exposed auto body shop workers. American journal of industrial medicine, 2001, Volume: 39, Issue:6 Topics: Adolescent; Adult; Aged; Air Pollutants, Occupational; Analysis of Variance; Asthma; Automobiles; Chi-Square Distribution; Cross-Sectional Studies; Cyanates; Epidemiologic Studies; Female; Humans; Isocyanates; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Paint; Statistics, Nonparametric; Surveys and Questionnaires	2001
Hypersensitivity pneumonitis induced by hexamethylene diisocyanate. Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:7 Topics: Alveolitis, Extrinsic Allergic; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bronchoalveolar Lavage Fluid; CD56 Antigen; Cyanates; Humans; Isocyanates; Killer Cells, Natural; Lymphocyte Subsets; Male; Middle Aged; Occupational Diseases; Paintings; Receptors, IgG	1992
Immunologic hemorrhagic pneumonia caused by isocyanates. The American review of respiratory disease, 1990, Volume: 141, Issue:1 Topics: Acute Disease; Adult; Cyanates; Enzyme-Linked Immunosorbent Assay; Hemorrhage; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Lung; Male; Occupational Diseases; Pneumonia; Radiography; Serum Albumin; Toluene 2,4-Diisocyanate	1990
The use of an immunoassay index for antibodies against isocyanate human protein conjugates and application to human isocyanate disease. The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:1 Topics: Antibodies; Antibody Specificity; Blood Proteins; Cyanates; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Toluene 2,4-Diisocyanate	1990
Decreased lung function and exposure to diisocyanates (HDI and HDI-BT) in car repair painters: observations on re-examination 6 years after initial study. American journal of industrial medicine, 1990, Volume: 17, Issue:3 Topics: Adult; Air Pollutants, Occupational; Automobiles; Cyanates; Environmental Exposure; Humans; Isocyanates; Longitudinal Studies; Lung; Male; Occupational Diseases; Paint; Respiratory Function Tests; Smoking; Sweden	1990
Immunologic specificity of isocyanate-induced IgE antibodies in serum from 10 sensitized workers. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:1 Topics: Antibody Specificity; Asthma; Carrier Proteins; Cyanates; Haptens; Humans; Immunoglobulin E; Isocyanates; Male; Occupational Diseases; Radioallergosorbent Test; Serum Albumin; Toluene 2,4-Diisocyanate	1989
Isocyanate exposure and hypersensitivity pneumonitis--report of a probable case and prevalence of specific immunoglobulin G antibodies among exposed individuals. Scandinavian journal of work, environment & health, 1989, Volume: 15, Issue:3 Topics: Adult; Air Pollutants, Occupational; Alveolitis, Extrinsic Allergic; Cyanates; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Isocyanates; Lacquer; Male; Occupational Diseases; Paint	1989
Specific serum antibodies against isocyanates: association with occupational asthma. The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:4 Pt 1 Topics: Antibodies; Asthma; Cyanates; Female; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Male; Occupational Diseases; Skin Tests	1989
Prospective immunologic and clinical study of a population exposed to hexamethylene diisocyanate. The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:4 Topics: Antibodies; Cyanates; Humans; Immunoglobulin E; Immunoglobulin G; Isocyanates; Occupational Diseases; Prospective Studies; Respiratory Hypersensitivity; Surveys and Questionnaires	1988