1-6-anhydro-3-4-dideoxy-beta-d-glycero-hex-3-enopyran-2-ulose and Liver-Neoplasms

1-6-anhydro-3-4-dideoxy-beta-d-glycero-hex-3-enopyran-2-ulose has been researched along with Liver-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 1-6-anhydro-3-4-dideoxy-beta-d-glycero-hex-3-enopyran-2-ulose and Liver-Neoplasms

ArticleYear
Cytotoxic effect of levoglucosenone and related derivatives against human hepatocarcinoma cell lines.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Levoglucosenone has been used as template for the synthesis of a wide variety of compounds with an impressive structural variability. However, scarce work has been done regarding the generation of new bioactive entities. Here we report the cytotoxic effect of levoglucosenone and some related derivatives against hepatocarcinoma cell lines. Compounds were obtained in only one synthetic step and one of them showed an activity within the range of IC50 values of cisplatin, a frequently administered chemotherapy drug.

    Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Glucose; Humans; Liver Neoplasms

2016