1,5-dihydroxyisoquinoline has been researched along with Diabetic Neuropathies in 3 studies
1,5-dihydroxyisoquinoline: structure in first source
isoquinoline-1,5-diol : An isoquinolinol that is isoquinoline in which the hydrogens at positions 1 and 5 are replaced by hydroxy groups.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic rats developed thermal hyperalgesia (assessed by paw-withdrawal and tail-flick tests), mechanical hyperalgesia (von Frey anesthesiometer/rigid filaments and Randall-Sellito tests), tactile allodynia (flexible von Frey filaments), and increased flinching behavior in phases 1 and 2 of the 2% formalin pain test." | 1.33 | Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy. ( Drel, VR; Ilnytska, O; Lyzogubov, VV; Mashtalir, N; Obrosova, IG; Pacher, P; Stevens, MJ; Yorek, MA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohammad, G | 1 |
| Siddiquei, MM | 1 |
| Abu El-Asrar, AM | 1 |
| Terashima, T | 1 |
| Kojima, H | 1 |
| Chan, L | 1 |
| Ilnytska, O | 1 |
| Lyzogubov, VV | 1 |
| Stevens, MJ | 1 |
| Drel, VR | 1 |
| Mashtalir, N | 1 |
| Pacher, P | 1 |
| Yorek, MA | 1 |
| Obrosova, IG | 1 |
3 other studies available for 1,5-dihydroxyisoquinoline and Diabetic Neuropathies
| Article | Year |
|---|---|
Poly (ADP-ribose) polymerase mediates diabetes-induced retinal neuropathy.
Topics: Acetophenones; Animals; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Experimental; Diabetic | 2013 |
Bone marrow expression of poly(ADP-ribose) polymerase underlies diabetic neuropathy via hematopoietic-neuronal cell fusion.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Fusion; Cells, Cultured; Diabetes Mell | 2012 |
Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.
Topics: Animals; Apoptosis; Arthropathy, Neurogenic; Blood Glucose; Body Weight; Diabetes Mellitus, Experime | 2006 |