1,5-dihydroxyisoquinoline has been researched along with Acute Promyelocytic Leukemia in 1 studies
1,5-dihydroxyisoquinoline: structure in first source
isoquinoline-1,5-diol : An isoquinolinol that is isoquinoline in which the hydrogens at positions 1 and 5 are replaced by hydroxy groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " NB4 cells treated with ATRA in combination with 1,25 D(3), a monocytic differentiation inducer, while continuing to reduce NBT also failed to mature into neutrophils or monocytes and again showed features of apoptosis." | 1.31 | All trans retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor. ( Berry, DM; Meckling-Gill, KA; Williams, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berry, DM | 1 |
| Williams, K | 1 |
| Meckling-Gill, KA | 1 |
1 other study available for 1,5-dihydroxyisoquinoline and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
All trans retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor.
Topics: Apoptosis; Benzamides; Calcitriol; Cell Differentiation; Cell Division; DNA Fragmentation; Enzyme In | 2000 |