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1,4-phenylenebis(methylene)selenocyanate and Colonic Neoplasms

1,4-phenylenebis(methylene)selenocyanate has been researched along with Colonic Neoplasms in 7 studies

1,4-phenylenebis(methylene)selenocyanate: structure given in first source; inhibits DMBA-induced carcinogenesis by inhibiting DMBA-DNA adduct formation

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of p-XSC against colon cancer is significantly augmented by a low-fat diet."1.31Mechanisms in the chemoprevention of colon cancer: modulation of protein kinase C, tyrosine protein kinase and diacylglycerol kinase activities by 1,4-phenylenebis-(methylene)selenocyanate and impact of low-fat diet. ( El-Bayoumy, K; Hirose, Y; Rao, CV; Reddy, BS; Simi, B; Upadhyaya, P, 2000)
"We have consistently shown that several synthetic Organoselenium compounds are superior cancer chemopreventive agents and less toxic than selenite or certain naturally occurring selenoamino acids."1.31Chemoprevention of colon cancer by a glutathione conjugate of 1,4-phenylenebis(methylene)selenocyanate, a novel organoselenium compound with low toxicity. ( Cooma, I; El-Bayoumy, K; Rao, CV; Reddy, BS; Rodriguez, JG; Simi, B; Wang, CQ, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartram, HP1
Krüger, S1
Dusel, G1
El-Bayoumy, K6
Upadhyaya, P4
Scheppach, W1
Narayanan, BA1
Narayanan, NK1
Desai, D1
Pittman, B2
Reddy, BS6
Rivenson, A2
Rao, CV4
Samaha, HS1
Hamid, R1
Simi, B2
Hirose, Y1
Wang, CQ1
Rodriguez, JG1
Cooma, I1
Kulkarni, N1

Other Studies

7 other studies available for 1,4-phenylenebis(methylene)selenocyanate and Colonic Neoplasms

ArticleYear
Antiproliferative effect of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) on colonic epithelium of patients with adenomatous polyps in vitro.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2003, Volume: 12, Issue:6

    Topics: Adenomatous Polyps; Anticarcinogenic Agents; Biomarkers; Biopsy; Cell Culture Techniques; Cell Divis

2003
Effects of a combination of docosahexaenoic acid and 1,4-phenylene bis(methylene) selenocyanate on cyclooxygenase 2, inducible nitric oxide synthase and beta-catenin pathways in colon cancer cells.
    Carcinogenesis, 2004, Volume: 25, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Blotting, Western; Caco-2 Cells; Cell Survival; Colo

2004
Chemoprevention of colon cancer by organoselenium compounds and impact of high- or low-fat diets.
    Journal of the National Cancer Institute, 1997, Apr-02, Volume: 89, Issue:7

    Topics: Adenocarcinoma; Analysis of Variance; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neopla

1997
The role of apoptosis in the modulation of colon carcinogenesis by dietary fat and by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary F

1997
Mechanisms in the chemoprevention of colon cancer: modulation of protein kinase C, tyrosine protein kinase and diacylglycerol kinase activities by 1,4-phenylenebis-(methylene)selenocyanate and impact of low-fat diet.
    International journal of oncology, 2000, Volume: 16, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Colonic Neoplasms; Diacylglycerol Kinase; Dietary Fats; Dinoprost;

2000
Chemoprevention of colon cancer by a glutathione conjugate of 1,4-phenylenebis(methylene)selenocyanate, a novel organoselenium compound with low toxicity.
    Cancer research, 2001, May-01, Volume: 61, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Cyclooxygenase 1; Cy

2001
Chemoprevention of colon carcinogenesis by the synthetic organoselenium compound 1,4-phenylenebis(methylene)selenocyanate.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Body Weight; Colonic Neopla

1992