1,4-dioxane has been researched along with Liver Neoplasms in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Budinsky, R; Corey, L; Crissman, J; Golden, R; Klapacz, J; Lafranconi, M; LeBaron, M; Pleus, R | 1 |
| Burleigh-Flayer, H; Dourson, M; McConnell, EE; Nance, P; Parker, A; Reichard, J; Vincent, M | 1 |
| Eck, WS; Fishbein, JC; Ginevan, B; Koissi, N; Roebuck, BD; Shah, NH | 1 |
| Stott, WT; Watanabe, PG | 1 |
| Leung, HW; Paustenbach, DJ | 1 |
| Andersen, ME; Gargas, ML; McCroskey, PS; Park, CN; Reitz, RH | 1 |
1 review(s) available for 1,4-dioxane and Liver Neoplasms
| Article | Year |
|---|---|
Differentiation of genetic versus epigenetic mechanisms of toxicity and its application to risk assessment.
Topics: Animals; Biological Assay; Butadienes; Carcinogens; Dioxanes; DNA; DNA Repair; Dose-Response Relationship, Drug; Kidney Neoplasms; Kinetics; Liver Neoplasms; Models, Biological; Mutagenicity Tests; Mutation; Neoplasms; Risk; Tetrachloroethylene | 1982 |
5 other study(ies) available for 1,4-dioxane and Liver Neoplasms
| Article | Year |
|---|---|
A 90-day drinking water study in mice to characterize early events in the cancer mode of action of 1,4-dioxane.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Cell Survival; Dioxanes; Dose-Response Relationship, Drug; Drinking Water; Female; Liver; Liver Neoplasms; Mice; Toxicity Tests, Subchronic | 2021 |
Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment.
Topics: Administration, Oral; Animals; Dioxanes; Dose-Response Relationship, Drug; Drinking Water; Female; Hyperplasia; Liver; Liver Neoplasms; Male; Mice; Models, Biological; Risk Assessment; Solvents | 2014 |
Lactone metabolite common to the carcinogens dioxane, diethylene glycol, and N-nitrosomorpholine: aqueous chemistry and failure to mediate liver carcinogenesis in the F344 rat.
Topics: Animals; Carcinogens; Dioxanes; Ethylene Glycols; Lactones; Liver; Liver Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred F344 | 2012 |
Cancer risk assessment for dioxane based upon a physiologically-based pharmacokinetic approach.
Topics: Animals; Carcinoma, Hepatocellular; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Environmental Exposure; Humans; Linear Models; Liver; Liver Neoplasms; Mathematics; Models, Biological; Rats; Risk Factors | 1990 |
Development of a physiologically based pharmacokinetic model for risk assessment with 1,4-dioxane.
Topics: Animals; Carcinogens, Environmental; Computer Simulation; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Models, Biological; Rats; Risk; Solubility | 1990 |