Page last updated: 2024-08-23

1,4-dioxane and Cancer of Liver

1,4-dioxane has been researched along with Cancer of Liver in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (16.67)	18.7374
1990's	2 (33.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (33.33)	24.3611
2020's	1 (16.67)	2.80

Authors

Authors	Studies
Budinsky, R; Corey, L; Crissman, J; Golden, R; Klapacz, J; Lafranconi, M; LeBaron, M; Pleus, R	1
Burleigh-Flayer, H; Dourson, M; McConnell, EE; Nance, P; Parker, A; Reichard, J; Vincent, M	1
Eck, WS; Fishbein, JC; Ginevan, B; Koissi, N; Roebuck, BD; Shah, NH	1
Stott, WT; Watanabe, PG	1
Leung, HW; Paustenbach, DJ	1
Andersen, ME; Gargas, ML; McCroskey, PS; Park, CN; Reitz, RH	1

Reviews

1 review(s) available for 1,4-dioxane and Cancer of Liver

Article	Year
Differentiation of genetic versus epigenetic mechanisms of toxicity and its application to risk assessment. Drug metabolism reviews, 1982, Volume: 13, Issue:5 Topics: Animals; Biological Assay; Butadienes; Carcinogens; Dioxanes; DNA; DNA Repair; Dose-Response Relationship, Drug; Kidney Neoplasms; Kinetics; Liver Neoplasms; Models, Biological; Mutagenicity Tests; Mutation; Neoplasms; Risk; Tetrachloroethylene	1982

Article

Year

Differentiation of genetic versus epigenetic mechanisms of toxicity and its application to risk assessment.

Drug metabolism reviews, 1982, Volume: 13, Issue:5

Topics: Animals; Biological Assay; Butadienes; Carcinogens; Dioxanes; DNA; DNA Repair; Dose-Response Relationship, Drug; Kidney Neoplasms; Kinetics; Liver Neoplasms; Models, Biological; Mutagenicity Tests; Mutation; Neoplasms; Risk; Tetrachloroethylene

1982

Other Studies

5 other study(ies) available for 1,4-dioxane and Cancer of Liver

Article	Year
A 90-day drinking water study in mice to characterize early events in the cancer mode of action of 1,4-dioxane. Regulatory toxicology and pharmacology : RTP, 2021, Volume: 119 Topics: Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Cell Survival; Dioxanes; Dose-Response Relationship, Drug; Drinking Water; Female; Liver; Liver Neoplasms; Mice; Toxicity Tests, Subchronic	2021
Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment. Regulatory toxicology and pharmacology : RTP, 2014, Volume: 68, Issue:3 Topics: Administration, Oral; Animals; Dioxanes; Dose-Response Relationship, Drug; Drinking Water; Female; Hyperplasia; Liver; Liver Neoplasms; Male; Mice; Models, Biological; Risk Assessment; Solvents	2014
Lactone metabolite common to the carcinogens dioxane, diethylene glycol, and N-nitrosomorpholine: aqueous chemistry and failure to mediate liver carcinogenesis in the F344 rat. Chemical research in toxicology, 2012, May-21, Volume: 25, Issue:5 Topics: Animals; Carcinogens; Dioxanes; Ethylene Glycols; Lactones; Liver; Liver Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred F344	2012
Cancer risk assessment for dioxane based upon a physiologically-based pharmacokinetic approach. Toxicology letters, 1990, Volume: 51, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Environmental Exposure; Humans; Linear Models; Liver; Liver Neoplasms; Mathematics; Models, Biological; Rats; Risk Factors	1990
Development of a physiologically based pharmacokinetic model for risk assessment with 1,4-dioxane. Toxicology and applied pharmacology, 1990, Volume: 105, Issue:1 Topics: Animals; Carcinogens, Environmental; Computer Simulation; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Models, Biological; Rats; Risk; Solubility	1990