Page last updated: 2024-08-18

1,4-butanediol and Chemical Dependence

1,4-butanediol has been researched along with Chemical Dependence in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (66.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gibson, KM; Goodwin, AK; Weerts, EM1
Brunt, TM; van Amsterdam, JG; van den Brink, W1
Claridge, H; Corazza, O; Corkery, JM; Elliott, S; Goodair, C; Loi, B; Schifano, F1
Brown, PR; Gibson, KM; Goodwin, AK; Jakobs, C; Jansen, EE; Weerts, EM1
Duketis, E; Holtmann, M; Maier, J; Poustka, F; Radeloff, D; Schirman, S; Wagner, A; Wöckel, L; Zepf, FD1
Mitcheson, L; Winstock, AR1
Dematteis, M; Mallaret, M; Pennel, L1
Palmer, RB1
Atzeri, S; Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Maccioni, P; Maher, TJ; Orrù, A; Quang, LS1
Gibson, KM; Snead, OC1
Ashraf, T; Clarke, S; Dargan, PI; Greene, SL; Holt, DW; Ramsey, J; Shather, Z; Trivedy, C; Warren-Gash, C; Wood, DM1
Greter, J; Knudsen, K; Verdicchio, M1
Quang, LS; Shannon, M1
Hall, BJ; McCutcheon, JR; Peacock, EA; Smith, SW; Spillane, J; Zvosec, DL1
Baud, FJ; Fompeydie, D; Garnier, R; Mégarbane, B1

Reviews

8 review(s) available for 1,4-butanediol and Chemical Dependence

ArticleYear
GHB, GBL and 1,4-BD addiction.
    Current pharmaceutical design, 2014, Volume: 20, Issue:25

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Humans; Hydroxybutyrates; Substance-Related Disorders

2014
Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4-butanediol (1,4-BD; BDO): A literature review with a focus on UK fatalities related to non-medical use.
    Neuroscience and biobehavioral reviews, 2015, Volume: 53

    Topics: 4-Butyrolactone; Butylene Glycols; Female; Humans; Male; Sodium Oxybate; Substance-Related Disorders; United Kingdom

2015
[Withdrawal syndrome after abuse of GHB (Gamma-Hydroxybutyrate) and its physiological precursors - its relevance for child and adolescent psychiatrists].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2009, Volume: 37, Issue:5

    Topics: 4-Butyrolactone; Acute Disease; Adolescent; Anesthetics, Intravenous; Antipsychotic Agents; Benzodiazepines; Butylene Glycols; Child; Critical Care; Delusions; Diagnosis, Differential; Drug Interactions; Humans; Psychoses, Substance-Induced; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders

2009
New recreational drugs and the primary care approach to patients who use them.
    BMJ (Clinical research ed.), 2012, Feb-15, Volume: 344

    Topics: Alkaloids; Anesthetics, Dissociative; Anesthetics, Intravenous; Butylene Glycols; Central Nervous System Stimulants; Humans; Illicit Drugs; Ketamine; Primary Health Care; Referral and Consultation; Sodium Oxybate; Substance-Related Disorders

2012
[Current knowledge on gamma-hydroxybutyric acid (GHB), gamma-butyrolactone (GBL) and 1 ,4-butanediol (1,4-BD)].
    La Revue du praticien, 2012, Volume: 62, Issue:5

    Topics: 4-Butyrolactone; Butylene Glycols; Humans; Hydroxybutyrates; Illicit Drugs; Knowledge; Models, Biological; Substance-Related Disorders

2012
Gamma-butyrolactone and 1,4-butanediol: abused analogues of gamma-hydroxybutyrate.
    Toxicological reviews, 2004, Volume: 23, Issue:1

    Topics: 4-Butyrolactone; Body Temperature Regulation; Butylene Glycols; GABA Modulators; Humans; Illicit Drugs; Seizures; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders

2004
Gamma-hydroxybutyric acid.
    The New England journal of medicine, 2005, Jun-30, Volume: 352, Issue:26

    Topics: 4-Butyrolactone; Animals; Butylene Glycols; Humans; Hydroxybutyrates; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA; Substance Withdrawal Syndrome; Substance-Related Disorders

2005
Gamma-hydroxybutyrate, gamma-butyrolactone, and 1,4-butanediol: a case report and review of the literature.
    Pediatric emergency care, 2000, Volume: 16, Issue:6

    Topics: 4-Butyrolactone; Adjuvants, Anesthesia; Adolescent; Butylene Glycols; Emergency Medical Services; Female; Humans; Lorazepam; Seizures; Sodium Oxybate; Structure-Activity Relationship; Substance-Related Disorders; Treatment Outcome

2000

Other Studies

7 other study(ies) available for 1,4-butanediol and Chemical Dependence

ArticleYear
Physical dependence on gamma-hydroxybutrate (GHB) prodrug 1,4-butanediol (1,4-BD): time course and severity of withdrawal in baboons.
    Drug and alcohol dependence, 2013, Oct-01, Volume: 132, Issue:3

    Topics: Animals; Butylene Glycols; Conditioning, Operant; Infusions, Parenteral; Male; Papio anubis; Prodrugs; Severity of Illness Index; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

2013
Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons.
    Psychopharmacology, 2009, Volume: 204, Issue:3

    Topics: 4-Butyrolactone; Animals; Area Under Curve; Behavior, Animal; Butylene Glycols; Conditioning, Operant; Dose-Response Relationship, Drug; Food; GABA Modulators; Male; Motor Skills; Papio; Prodrugs; Reward; Sodium Oxybate; Substance-Related Disorders

2009
Withdrawal syndrome from gamma-hydroxybutyric acid (GHB) and 1,4-butanediol (1,4-BD) in Sardinian alcohol-preferring rats.
    Brain research. Brain research protocols, 2005, Volume: 15, Issue:2

    Topics: Animals; Butylene Glycols; Disease Models, Animal; GABA-B Receptor Antagonists; Hydroxybutyrates; Male; Morpholines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders

2005
Medical and legal confusion surrounding gamma-hydroxybutyrate (GHB) and its precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4BD).
    QJM : monthly journal of the Association of Physicians, 2008, Volume: 101, Issue:1

    Topics: 4-Butyrolactone; Adult; Aged; Butylene Glycols; Emergency Medical Services; Female; Humans; Illicit Drugs; Length of Stay; Male; Middle Aged; Retrospective Studies; Sodium Oxybate; Substance-Related Disorders

2008
High mortality rates among GHB abusers in Western Sweden.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:3

    Topics: 4-Butyrolactone; Adolescent; Adult; Anesthetics, Intravenous; Butylene Glycols; Cause of Death; Female; Forensic Medicine; Humans; Illicit Drugs; Male; Police; Sodium Oxybate; Substance Abuse Detection; Substance-Related Disorders; Sweden

2008
Adverse events, including death, associated with the use of 1,4-butanediol.
    The New England journal of medicine, 2001, Jan-11, Volume: 344, Issue:2

    Topics: Adult; Butylene Glycols; Dietary Supplements; Fatal Outcome; Female; Humans; Male; Psychomotor Agitation; Pulmonary Edema; Sodium Oxybate; Substance Withdrawal Syndrome; Substance-Related Disorders; Unconsciousness; Vomiting

2001
Treatment of a 1,4-butanediol poisoning with fomepizole.
    Journal of toxicology. Clinical toxicology, 2002, Volume: 40, Issue:1

    Topics: Adult; Antidotes; Butylene Glycols; Coma; Fomepizole; Humans; Hydroxybutyrates; Infusions, Intravenous; Male; Pyrazoles; Seizures; Solvents; Substance-Related Disorders; Treatment Outcome

2002