1,4-bis(2-(3,5-dichloropyridyloxy))benzene has been researched along with Hyperplasia in 11 studies
1,4-bis(2-(3,5-dichloropyridyloxy))benzene: potent phenobarbital-like inducer of microsomal monooxygenase activity; structure given in first source
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present experiments we investigated the efficiency of a primary hepatocyte mitogen 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOB) on two different liver cirrhosis/fibrosis models in mice induced by chronic administration of CCl(4) and thioacetamide respectively." | 3.78 | 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene induces substantial hyperplasia in fibrotic mouse liver. ( Bugyik, E; Dezso, K; Nagy, P; Paku, S; Szurián, K; Turányi, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blanco-Bose, WE | 1 |
| Murphy, MJ | 1 |
| Ehninger, A | 1 |
| Offner, S | 1 |
| Dubey, C | 1 |
| Huang, W | 2 |
| Moore, DD | 2 |
| Trumpp, A | 1 |
| Takagi, S | 2 |
| Ohashi, K | 2 |
| Utoh, R | 2 |
| Tatsumi, K | 2 |
| Shima, M | 2 |
| Okano, T | 2 |
| Taminishi, S | 1 |
| Yoshioka, A | 1 |
| Mitchell, KA | 1 |
| Wilson, SR | 1 |
| Elferink, CJ | 1 |
| Kowalik, MA | 1 |
| Saliba, C | 1 |
| Pibiri, M | 4 |
| Perra, A | 2 |
| Ledda-Columbano, GM | 5 |
| Sarotto, I | 1 |
| Ghiso, E | 1 |
| Giordano, S | 1 |
| Columbano, A | 5 |
| Chen, T | 1 |
| Chen, Q | 1 |
| Xu, Y | 1 |
| Zhou, Q | 1 |
| Zhu, J | 1 |
| Zhang, H | 1 |
| Wu, Q | 1 |
| Xu, J | 1 |
| Yu, C | 1 |
| Bugyik, E | 1 |
| Dezso, K | 1 |
| Turányi, E | 1 |
| Szurián, K | 1 |
| Paku, S | 1 |
| Nagy, P | 1 |
| Locker, J | 2 |
| Tian, J | 2 |
| Carver, R | 1 |
| Concas, D | 1 |
| Cossu, C | 2 |
| Menegazzi, M | 1 |
| Simbula, M | 1 |
| Pisanu, A | 1 |
| Uccheddu, A | 1 |
| Piga, R | 1 |
| Shinozuka, H | 1 |
| De Luca, V | 1 |
| Cerignoli, F | 1 |
| Tripodi, M | 1 |
11 other studies available for 1,4-bis(2-(3,5-dichloropyridyloxy))benzene and Hyperplasia
| Article | Year |
|---|---|
C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia.
Topics: Animals; Cell Proliferation; Constitutive Androstane Receptor; Disease Models, Animal; Forkhead Box | 2008 |
Suitable reference genes for the analysis of direct hyperplasia in mice.
Topics: Animals; Cell Proliferation; Gene Expression; Gene Expression Profiling; Genetic Markers; Hepatocyte | 2008 |
Effects on coagulation factor production following primary hepatomitogen-induced direct hyperplasia.
Topics: Animals; Blood Coagulation Factors; Blood Coagulation Tests; Disease Models, Animal; Female; Gene Ex | 2009 |
The activated aryl hydrocarbon receptor synergizes mitogen-induced murine liver hyperplasia.
Topics: Animals; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Femal | 2010 |
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell | 2011 |
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism.
Topics: Acetaminophen; Animals; Cell Proliferation; Constitutive Androstane Receptor; Gene Expression; Hepat | 2012 |
1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene induces substantial hyperplasia in fibrotic mouse liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Bromodeoxyuridine; Carbon Tetrachloride; Cell Pr | 2012 |
A common set of immediate-early response genes in liver regeneration and hyperplasia.
Topics: Animals; Cell Division; Cell Survival; Female; Genes, Immediate-Early; Hepatectomy; Hyperplasia; Liv | 2003 |
Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia.
Topics: Animals; Antigens, Differentiation; Cell Proliferation; Constitutive Androstane Receptor; Female; Hy | 2005 |
Potential utility of xenobiotic mitogens in the context of liver regeneration in the elderly and living-related transplantation.
Topics: Age Factors; Animals; Female; Hepatectomy; Hyperplasia; Liver; Liver Regeneration; Liver Transplanta | 2008 |
Increased expression of c-fos, c-jun and LRF-1 is not required for in vivo priming of hepatocytes by the mitogen TCPOBOP.
Topics: Animals; Bromodeoxyuridine; Carcinogens; DNA; Female; Genes, fos; Genes, jun; Genes, myc; Hyperplasi | 1997 |