1,4-bis(2-(3,5-dichloropyridyloxy))benzene has been researched along with Abnormalities, Autosome in 3 studies
1,4-bis(2-(3,5-dichloropyridyloxy))benzene: potent phenobarbital-like inducer of microsomal monooxygenase activity; structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tamoxifen treatment resulted in the induction of aneuploidy in approximately 70% of the examined hepatocytes at the doses used." | 5.29 | Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats. ( Bahnub, N; Dragan, YP; Jordan, VC; Pitot, HC; Sargent, LM; Sattler, CA; Sattler, GL; Schroeder, P; Wiley, JE, 1994) |
| "Tamoxifen treatment resulted in the induction of aneuploidy in approximately 70% of the examined hepatocytes at the doses used." | 1.29 | Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats. ( Bahnub, N; Dragan, YP; Jordan, VC; Pitot, HC; Sargent, LM; Sattler, CA; Sattler, GL; Schroeder, P; Wiley, JE, 1994) |
| "A relevant increase in the frequency of chromosomal aberrations was observed in both cell types." | 1.27 | Clastogenic effects induced in mice and rats by 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a phenobarbital-like enzyme inducer and liver tumour promoter. ( Quattrone, C; Rosselli, F; Rossi, AM; Zaccaro, L, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sargent, LM | 1 |
| Dragan, YP | 1 |
| Bahnub, N | 1 |
| Wiley, JE | 1 |
| Sattler, CA | 1 |
| Schroeder, P | 1 |
| Sattler, GL | 1 |
| Jordan, VC | 1 |
| Pitot, HC | 1 |
| Dragani, TA | 1 |
| Barale, R | 1 |
| Parodi, S | 1 |
| Taningher, M | 1 |
| Zucconi, D | 1 |
| Della Porta, G | 1 |
| Rossi, AM | 1 |
| Zaccaro, L | 1 |
| Rosselli, F | 1 |
| Quattrone, C | 1 |
3 other studies available for 1,4-bis(2-(3,5-dichloropyridyloxy))benzene and Abnormalities, Autosome
| Article | Year |
|---|---|
Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Chromosome Disorders; Dose-Response Relationship, Drug; | 1994 |
Negative results of short-term genotoxicity tests with 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene.
Topics: Animals; Chromosome Aberrations; DNA; Hydrogen-Ion Concentration; Liver; Male; Mice; Micronucleus Te | 1990 |
Clastogenic effects induced in mice and rats by 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a phenobarbital-like enzyme inducer and liver tumour promoter.
Topics: Animals; Biotransformation; Bone Marrow; Carcinogens; Chromosome Aberrations; Dose-Response Relation | 1988 |