1-4-benzothiazine has been researched along with Tuberculosis* in 1 studies
1 other study(ies) available for 1-4-benzothiazine and Tuberculosis
| Article | Year |
|---|---|
Synthesis and antitubercular screening of some novel 4H-1,4- benzothiazines and their sulfones under environment benign solvent free conditions as future anti-tubercular agents.
Some novel analogs of 4H-1,4-benzothiazines were synthesized under environmentally benign solvent free conditions by one pot oxidative cyclocondensation of substituted 2- aminobenzenthiols with compounds having active methylene group and then converted in to sulfones. These compounds were examined as antitubercular agents against Mycobacterium tuberculosis H37Rv using REMA plate method. The best results have MICs from 6.4 to 8.8 μg/mL, comparable to phenothiazines. IR, NMR and mass spectral investigations are included for structural elucidation. Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Sulfones; Thiazines; Tuberculosis | 2015 |