1-4-benzothiazine and Mycoses

1-4-benzothiazine has been researched along with Mycoses* in 1 studies

Other Studies

1 other study(ies) available for 1-4-benzothiazine and Mycoses

Article	Year
Synthesis and biological activity of substituted 4H-1,4-benzothiazines, their sulfones, and ribofuranosides. Nucleosides, nucleotides & nucleic acids, 2013, Volume: 32, Issue:2 The present article describes the synthesis of new 4H-1,4-benzothiazines via condensation and oxidative cyclization of substituted 2-aminobenzenethiols with β-diketones/β-ketoesters in dimethyl sulfoxide. The oxidation of these synthesized 4H-1,4-benzothiazines with 30% hydrogen peroxide in glacial acetic acid yielded 4H-1,4-benzothiazine sulfones and the reaction of these synthesized benzothiazines with sugar (β-D-ribofuranose-1-acetate-2,3,5-tribenzoate) afforded the new ribofuranosides. These compounds were evaluated for their antioxidant and antimicrobial activities (using broth microdilution method). The structural assignments of the synthesized compounds were made on the basis of elemental analyses and spectroscopic data. Topics: Anti-Infective Agents; Antioxidants; Bacteria; Bacterial Infections; Biphenyl Compounds; Free Radicals; Fungi; Humans; Mycoses; Picrates; Ribose; Structure-Activity Relationship; Sulfones; Thiazines	2013

Article

Year

Synthesis and biological activity of substituted 4H-1,4-benzothiazines, their sulfones, and ribofuranosides.

Nucleosides, nucleotides & nucleic acids, 2013, Volume: 32, Issue:2

The present article describes the synthesis of new 4H-1,4-benzothiazines via condensation and oxidative cyclization of substituted 2-aminobenzenethiols with β-diketones/β-ketoesters in dimethyl sulfoxide. The oxidation of these synthesized 4H-1,4-benzothiazines with 30% hydrogen peroxide in glacial acetic acid yielded 4H-1,4-benzothiazine sulfones and the reaction of these synthesized benzothiazines with sugar (β-D-ribofuranose-1-acetate-2,3,5-tribenzoate) afforded the new ribofuranosides. These compounds were evaluated for their antioxidant and antimicrobial activities (using broth microdilution method). The structural assignments of the synthesized compounds were made on the basis of elemental analyses and spectroscopic data.

Topics: Anti-Infective Agents; Antioxidants; Bacteria; Bacterial Infections; Biphenyl Compounds; Free Radicals; Fungi; Humans; Mycoses; Picrates; Ribose; Structure-Activity Relationship; Sulfones; Thiazines

2013