Compounds > 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
Page last updated: 2024-09-03

1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Prostatic Neoplasms

1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid has been researched along with Prostatic Neoplasms in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (26.00)29.6817
2010's30 (60.00)24.3611
2020's7 (14.00)2.80

Authors

AuthorsStudies
Chen, Y; Hua, Q; Li, H; Wang, L; Xu, T1
Bao, G; Chen, L; He, C; Li, Y; Liu, X; Ma, X; Xiang, G; Zhang, X; Zhou, H; Zhu, X1
Baun, C; Dam, JH; Ewald, JD; Gammelsrød, VS; Hildebrandt, MG; Kristensen, BW; Olsen, BB; Thisgaard, H1
Appelhans, D; Boye, S; Daeg, J; Janke, A; Lederer, A; Shi, X; Temme, A; Voit, B; Xu, X; Zhao, J; Zhao, L1
Aluicio-Sarduy, E; Barnhart, TE; Boros, E; Devaraj, J; Engle, JW; Martin, KE; Olson, AP; Thiele, NA; Vaughn, BA; Wilson, JJ1
Brygoła, K; Ciach, T; Duszak, J; Janczewska, M; Karczmarczyk, U; Kopyra, K; Pikus, G; Świątkowska, A; Szkop, M; Walczak, J; Żuk, MT1
Cheng, Z; Hu, X; Lacivita, E; Leopoldo, M; Liu, H; Liu, Y; Lucente, E1
Escudero-Castellanos, A; Ferro-Flores, G; Isaac-Olivé, K; Luna-Gutiérrez, M; Morales-Ávila, E; Ocampo-García, B; Santos-Cuevas, C1
Akporji, N; Dobson, DE; Hornak, JP; Jones, KG; Nastiuk, KL; Schmitthenner, HF; Soika, DQM1
Kaur, H; Oupicky, D; Peng, F; Yuan, J; Zhang, H1
Ananias, HJ; Carlucci, G; de Jong, IJ; Dierckx, RA; Elsinga, PH; Helfrich, W; Hoving, HD; Liu, S; Yu, Z1
Deeg, M; Echner, H; Ernemann, U; Heckl, S; Kalbacher, H; Klose, U; Nägele, T; Schwentner, C; Sheikh, S; Sturzu, A1
Huxol, E; Mindt, TL; Valverde, IE1
Buckway, B; Frazier, N; Ghandehari, H; Gormley, AJ; Ray, A1
Ackerstaff, E; Anderson, M; Andreev, OA; Blasberg, RG; Carlin, SD; Divilov, V; Engelman, DM; Koutcher, JA; Kruchevsky, N; Lewis, JS; Reshetnyak, YK; Serganova, I; Sevak, KK; Viola-Villegas, NT1
Hoffman, TJ; Lewis, MR; Liu, D; Miao, Y; Rold, TL; Schehr, R; Smith, CJ; Stott Reynolds, TJ; Xu, J1
Burnet, JC; de Araújo, EB; Finucane, C; Foster, JM; Hudson, CD; Mather, SJ; Mengatti, J; Pasqualoto, KFM; Pujatti, PB; Sosabowski, JK1
Cho, EH; Choi, SM; Kim, JJ; Lee, SY; Lim, JC; Nam, SS; Park, SH; Park, UJ1
Afshar-Oromieh, A; Bauder-Wüst, U; Benešová, M; Eder, M; Haberkorn, U; Kopka, K; Kratochwil, C; Mier, W; Schäfer, M1
Berthelsen, AK; Brandt-Larsen, M; Brasso, K; Christensen, C; Holm, S; Højgaard, L; Kjaer, A; Klausen, TL; Kroman, N; Loft, A; Madsen, J; Nielsen, CH; Pappot, H; Persson, M; Ploug, M; Skovgaard, D; Thurison, T1
Bauder-Wüst, U; Benešová, M; Eder, M; Haberkorn, U; Klika, KD; Kopka, K; Mier, W; Schäfer, M1
Ciarmiello, A; Giovacchini, G; Giovannini, E; Riondato, M1
Bowles, N; Channappa, D; Chea, J; Colcher, D; Crow, D; Delgado, MK; Li, L; Poku, E; Shively, JE; Szpikowska, B; Wong, JYC; Wong, P; Yazaki, PJ1
Figueroa, SD; Garrison, JC; Hoffman, TJ; Naz, F; Rold, TL; Sieckman, GL; Sublett, SV; Volkert, WA1
Abd-Elgaliel, WR; Figueroa, SD; Gallazzi, F; Garrison, JC; Hoffman, TJ; Lever, SZ; Rold, TL; Sieckman, GL1
Borkowski, S; Cescato, R; Forrer, F; Graham, K; Maecke, HR; Mansi, R; Reubi, JC; Wang, X; Waser, B1
Cai, H; Conti, PS; Huang, CW; Li, Z; Shahinian, T1
Altmann, A; Askoxylakis, V; Debus, J; Haberkorn, U; Markert, A; Marr, A; Mier, W; Rana, S; Zitzmann-Kolbe, S; Zoller, F1
Azhdarinia, A; Chan, W; Hall, MA; Kwon, S; Lachance, PA; Price, RE; Ranganathan, R; Robinson, H; Sevick-Muraca, EM1
Bander, NH; Evans, MJ; Kim, S; Larson, SM; Navarro, V; Sawyers, CL; Smith-Jones, PM; Wongvipat, J1
Banerjee, SR; Byun, Y; Foss, CA; Fox, JJ; Green, G; Lupold, SE; Mease, RC; Nimmagadda, S; Pomper, MG; Pullambhatla, M1
Abrahmsén, L; Bergman, T; Gräslund, T; Hofström, C; Malmberg, J; Orlova, A; Sandström, M; Sjöberg, A; Tolmachev, V1
Altai, M; Braun, A; Garske, U; Karlström, AE; Malmberg, J; Orlova, A; Perols, A; Sandström, M; Tolmachev, V; Varasteh, Z1
Azhdarinia, A; Ghosh, P; Hall, MA; Harvey, BR; Kolonin, AM; Pinkston, KL; Robinson, H; Sevick-Muraca, EM; Vazquez-Arreguin, K; Wilganowski, N1
Archimandritis, SC; Fellner, M; Koumarianou, E; Loktionova, NS; Mikolajczak, R; Pawlak, D; Roesch, F; Thews, O1
Andersson, K; Gräslund, T; Hofström, C; Orlova, A; Sandstrom, M; Strand, J; Tolmachev, V; Varasteh, Z1
Connal, LA; Hawker, CJ; Liu, Y; Pierce, RA; Pressly, ED1
Cai, Q; Goswami, LN; Hawthorne, MF; Jalisatgi, SS; Ma, L; Sarma, SJ1
DeNardo, GL; DeNardo, SJ; Jacobs, F; Kukis, DL; Lamborn, KR; Lara, PN; Natarajan, A; O'Donnell, RT; Richman, CM; Siantar, CL; Yuan, A1
Bander, NH; Goldsmith, SJ; Navarro, V; Smith-Jones, PM; Vallabhajosula, S1
DeNardo, GL; DeNardo, SJ1
Chew, HK; DeNardo, GL; Denardo, SJ; Goldstein, DS; Kukis, DL; Lamborn, KR; Lara, PN; Meares, CF; Natarajan, A; O'Donnell, RT; Richman, CM; Shen, S; Tuscano, JM; Wun, T; Yuan, A1
DeNardo, G; DeNardo, S; Lamborn, K; Miers, L; Natarajan, A; Richman, C; Yuan, A1
Cai, W; Cao, Q; Chen, K; Chen, X; Tice, DA; Wu, Y1
Eisenhut, M; Maecke, HR; Reubi, JC; Schuhmacher, J; Waser, B; Wild, D; Zhang, H1
Figueroa, SD; Garrison, JC; Hoffman, TJ; Jurisson, SS; Rold, TL; Sieckman, GL; Volkert, WA1
Beck, A; Echner, H; Feil, G; Gharabaghi, A; Heckl, S; Nagele, T; Regenbogen, M; Sturzu, A1
Bander, NH; Borchardt, P; Curcio, MJ; Frank, RK; Lai, LT; Ma, D; McDevitt, MR; Miederer, M; Pellegrini, V; Scheinberg, DA; Simon, J; Wu, K1
Cutler, CS; Hoffman, T; Hu, F; Jurisson, SS; Sieckman, G; Volkert, WA1

Reviews

1 review(s) available for 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Prostatic Neoplasms

ArticleYear
Radiopharmaceuticals for the Diagnosis and Therapy of Neuroendocrine Differentiated Prostate Cancer.
    Current radiopharmaceuticals, 2017, Volume: 10, Issue:1

    Topics: Bombesin; Gallium Radioisotopes; Gastrin-Releasing Peptide; Germanium; Heterocyclic Compounds, 1-Ring; Humans; Male; Neuroendocrine Tumors; Pentetic Acid; Phenotype; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Somatostatin; Tomography, Emission-Computed, Single-Photon

2017

Trials

2 trial(s) available for 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Prostatic Neoplasms

ArticleYear
First-in-human uPAR PET: Imaging of Cancer Aggressiveness.
    Theranostics, 2015, Volume: 5, Issue:12

    Topics: Breast Neoplasms; Copper Radioisotopes; Drug-Related Side Effects and Adverse Reactions; Female; Heterocyclic Compounds, 1-Ring; Humans; Male; Middle Aged; Molecular Imaging; Oligopeptides; Positron-Emission Tomography; Prognosis; Prostatic Neoplasms; Protein Binding; Receptors, Urokinase Plasminogen Activator; Urinary Bladder Neoplasms

2015
High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Breast Neoplasms; Cathepsins; Combined Modality Therapy; Cyclosporine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Mice; Middle Aged; Neutropenia; Paclitaxel; Prostatic Neoplasms; Radioimmunotherapy; Soft Tissue Neoplasms; Treatment Outcome; Yttrium Radioisotopes

2005

Other Studies

47 other study(ies) available for 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Prostatic Neoplasms

ArticleYear
Lutetium lu 177 vipivotide tetraxetan (Pluvicto) for prostate cancer.
    The Medical letter on drugs and therapeutics, 2022, 12-12, Volume: 64, Issue:1665

    Topics: Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Prostatic Neoplasms

2022
177Lu-DOTA-IBA Therapy in Prostate Cancer With Bone Metastases.
    Clinical nuclear medicine, 2023, Aug-01, Volume: 48, Issue:8

    Topics: Bone Neoplasms; Humans; Ibandronic Acid; Male; Prostatic Neoplasms; Radiopharmaceuticals

2023
Synthesis of novel DOTA-/AAZTA-based bifunctional chelators: Solution thermodynamics, peptidomimetic conjugation, and radiopharmaceutical evaluation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Gallium Radioisotopes; Humans; Male; Mice; Peptidomimetics; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Thermodynamics

2023
Preclinical evaluation of [
    Scientific reports, 2023, 11-01, Volume: 13, Issue:1

    Topics: Animals; Antigens, Surface; Cell Line, Tumor; Electrons; Glutamate Carboxypeptidase II; Humans; Male; Mice; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution

2023
Bivalent Peptide- and Chelator-Containing Bioconjugates as Toolbox Components for Personalized Nanomedicine.
    Biomacromolecules, 2020, 01-13, Volume: 21, Issue:1

    Topics: Animals; Antigens, Surface; Avidin; Biotin; Chelating Agents; Contrast Media; Dendrimers; Diagnostic Imaging; ErbB Receptors; Folic Acid; Glutamate Carboxypeptidase II; HEK293 Cells; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice, Inbred BALB C; Molecular Targeted Therapy; Nanomedicine; Peptides; Polyethylene Glycols; Prostatic Neoplasms; Xenograft Model Antitumor Assays

2020
Establishing Radiolanthanum Chemistry for Targeted Nuclear Medicine Applications.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Jan-27, Volume: 26, Issue:6

    Topics: Animals; Cell Line, Tumor; Contrast Media; Heterocyclic Compounds, 1-Ring; Humans; Lanthanum; Male; Mice; Positron Emission Tomography Computed Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Transplantation, Heterologous

2020
PSMA targeted conjugates based on dextran.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2021, Volume: 167

    Topics: Antigens, Surface; Cell Line, Tumor; Chelating Agents; Dextrans; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Male; Prostatic Neoplasms; Radiopharmaceuticals

2021
Novel
    Bioconjugate chemistry, 2018, 05-16, Volume: 29, Issue:5

    Topics: Animals; Bombesin; Copper Radioisotopes; Dimerization; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Male; Mice; Mice, Nude; PC-3 Cells; Peptides, Cyclic; Positron-Emission Tomography; Prostatic Neoplasms; Receptors, Bombesin; Tissue Distribution

2018
Synthesis and preclinical evaluation of the 177Lu-DOTA-PSMA(inhibitor)-Lys3-bombesin heterodimer designed as a radiotheranostic probe for prostate cancer.
    Nuclear medicine communications, 2019, Volume: 40, Issue:3

    Topics: Animals; Antigens, Surface; Bombesin; Cell Line, Tumor; Chemistry Techniques, Synthetic; Dimerization; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Lysine; Male; Mice; Prostatic Neoplasms; Radiochemistry; Radioisotopes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2019
Modular Synthesis of DOTA-Metal-Based PSMA-Targeted Imaging Agents for MRI and PET of Prostate Cancer.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2019, Nov-04, Volume: 25, Issue:61

    Topics: Contrast Media; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Male; Metals; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms

2019
Synthesis and characterization of theranostic poly(HPMA)-c(RGDyK)-DOTA-64Cu copolymer targeting tumor angiogenesis: tumor localization visualized by positron emission tomography.
    Molecular imaging, 2013, Volume: 12, Issue:3

    Topics: Animals; Copper Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Male; Methacrylates; Mice; Neovascularization, Pathologic; Polymers; Positron-Emission Tomography; Prostatic Neoplasms

2013
Preclinical evaluation of a novel ¹¹¹In-labeled bombesin homodimer for improved imaging of GRPR-positive prostate cancer.
    Molecular pharmaceutics, 2013, May-06, Volume: 10, Issue:5

    Topics: Animals; Bombesin; Cell Line, Tumor; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Mice; Mice, Nude; Prostatic Neoplasms; Radiopharmaceuticals; Receptors, Bombesin; Tomography, Emission-Computed, Single-Photon

2013
The gastrin/cholecystokinin-B receptor on prostate cells--a novel target for bifunctional prostate cancer imaging.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Feb-14, Volume: 52

    Topics: Animals; Cell Line, Tumor; Contrast Media; Fluorescent Dyes; Gadolinium; Gastrins; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Oligopeptides; Prostate; Prostatic Neoplasms; Receptor, Cholecystokinin B; Rhodamines

2014
Radiolabeled antagonistic bombesin peptidomimetics for tumor targeting.
    Journal of labelled compounds & radiopharmaceuticals, 2014, Volume: 57, Issue:4

    Topics: Amino Acid Sequence; Bombesin; Cell Line, Tumor; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Lutetium; Male; Peptide Fragments; Peptidomimetics; Prostatic Neoplasms; Proteolysis; Radioisotopes; Tomography, Emission-Computed, Single-Photon; Triazoles

2014
Gold nanorod-mediated hyperthermia enhances the efficacy of HPMA copolymer-90Y conjugates in treatment of prostate tumors.
    Nuclear medicine and biology, 2014, Volume: 41, Issue:3

    Topics: Acrylamides; Animals; Cell Line, Tumor; Female; Gold; Heterocyclic Compounds, 1-Ring; Humans; Hyperthermia, Induced; Male; Mice; Nanotubes; Prostatic Neoplasms; Tomography, Emission-Computed, Single-Photon; Yttrium Radioisotopes

2014
Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, May-20, Volume: 111, Issue:20

    Topics: Animals; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line, Tumor; Chelating Agents; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Hydrogen-Ion Concentration; Hypoxia; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Male; Membrane Proteins; Mice; Mice, Nude; Neoplasm Transplantation; Phenotype; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals

2014
Characterization and evaluation of DOTA-conjugated Bombesin/RGD-antagonists for prostate cancer tumor imaging and therapy.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:2

    Topics: Animals; Bombesin; Cell Line, Tumor; Copper Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Male; Mice; Oligopeptides; Prostatic Neoplasms; Receptors, Bombesin; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; X-Ray Microtomography

2015
Evaluation and comparison of a new DOTA and DTPA-bombesin agonist in vitro and in vivo in low and high GRPR expressing prostate and breast tumor models.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2015, Volume: 96

    Topics: Animals; Bombesin; Breast Neoplasms; Cell Line, Tumor; Drug Stability; Female; Heterocyclic Compounds, 1-Ring; Heterografts; Humans; In Vitro Techniques; Indium Radioisotopes; Male; Mice, SCID; Neoplasm Transplantation; Pentetic Acid; Prostatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Bombesin; Tissue Distribution

2015
Preclinical pharmacokinetic, biodistribution, imaging and therapeutic efficacy of (177)Lu-Labeled glycated bombesin analogue for gastrin-releasing peptide receptor-positive prostate tumor targeting.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:3

    Topics: Aminobenzoates; Animals; Bombesin; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glycosylation; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Prostatic Neoplasms; Radioisotopes; Receptors, Bombesin; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2015
Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:6

    Topics: Animals; Antigens, Surface; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; Dipeptides; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Peptides; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Radiotherapy; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution

2015
Linker Modification Strategies To Control the Prostate-Specific Membrane Antigen (PSMA)-Targeting and Pharmacokinetic Properties of DOTA-Conjugated PSMA Inhibitors.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Structure-Activity Relationship

2016
PET imaging of
    Nuclear medicine and biology, 2017, Volume: 47

    Topics: Animals; Antigens, Surface; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Drug Carriers; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Nanoparticles; Positron-Emission Tomography; Prostatic Neoplasms; Single-Chain Antibodies

2017
Evaluation of the pharmacokinetic effects of various linking group using the 111In-DOTA-X-BBN(7-14)NH2 structural paradigm in a prostate cancer model.
    Bioconjugate chemistry, 2008, Volume: 19, Issue:9

    Topics: 4-Aminobenzoic Acid; Animals; Binding, Competitive; Bombesin; Caprylates; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Male; Mice; Mice, SCID; Models, Biological; Neurotransmitter Agents; Organometallic Compounds; Prostatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals

2008
Design, synthesis, and biological evaluation of an antagonist-bombesin analogue as targeting vector.
    Bioconjugate chemistry, 2008, Volume: 19, Issue:10

    Topics: Animals; Bombesin; Cell Line, Tumor; Chelating Agents; Drug Design; Gene Expression; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Inhibitory Concentration 50; Male; Mice; Organometallic Compounds; Prostatic Neoplasms; Receptors, Bombesin; Staining and Labeling; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2008
Development of a potent DOTA-conjugated bombesin antagonist for targeting GRPr-positive tumours.
    European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:1

    Topics: Animals; Bombesin; Cell Line, Tumor; Drug Discovery; Female; HEK293 Cells; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Oligopeptides; Prostatic Neoplasms; Protein Transport; Receptors, Bombesin; Xenograft Model Antitumor Assays

2011
Biological stability evaluation of the α2β1 receptor imaging agents: diamsar and DOTA conjugated DGEA peptide.
    Bioconjugate chemistry, 2011, Feb-16, Volume: 22, Issue:2

    Topics: Animals; Cell Line, Tumor; Copper Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Integrin alpha2beta1; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Organometallic Compounds; Positron-Emission Tomography; Prostatic Neoplasms; Sarcosine; Tissue Distribution; Xenograft Model Antitumor Assays

2011
Challenges in optimizing a prostate carcinoma binding peptide, identified through the phage display technology.
    Molecules (Basel, Switzerland), 2011, Feb-14, Volume: 16, Issue:2

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Peptide Library; Peptides; Prostatic Neoplasms; Tissue Distribution

2011
Imaging prostate cancer lymph node metastases with a multimodality contrast agent.
    The Prostate, 2012, Feb-01, Volume: 72, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cell Adhesion Molecules; Cell Line, Tumor; Contrast Media; Copper Radioisotopes; Disease Models, Animal; Epithelial Cell Adhesion Molecule; Heterocyclic Compounds, 1-Ring; Humans; Indoles; Lymph Nodes; Lymphatic Metastasis; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Multimodal Imaging; Positron-Emission Tomography; Prostatic Neoplasms; Reproducibility of Results; ROC Curve; Tomography, X-Ray Computed

2012
Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jun-07, Volume: 108, Issue:23

    Topics: Androgen Antagonists; Androgens; Animals; Antibodies, Monoclonal; Antigens, Surface; Benzamides; Cell Line, Tumor; Copper Radioisotopes; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Immunoblotting; Male; Mice; Mice, SCID; Neoplasms, Experimental; Nitriles; Orchiectomy; Phenylthiohydantoin; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radiopharmaceuticals; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transplantation, Heterologous

2011
Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen.
    Angewandte Chemie (International ed. in English), 2011, Sep-19, Volume: 50, Issue:39

    Topics: Animals; Fluorescent Dyes; Heterocyclic Compounds, 1-Ring; Indium Radioisotopes; Male; Mice; Peptides; Porphyrins; Prostate-Specific Antigen; Prostatic Neoplasms; Protease Inhibitors; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous

2011
Imaging of insulinlike growth factor type 1 receptor in prostate cancer xenografts using the affibody molecule 111In-DOTA-ZIGF1R:4551.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Feasibility Studies; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Mice; Prostatic Neoplasms; Radionuclide Imaging; Receptor, IGF Type 1; Recombinant Fusion Proteins

2012
Comparative evaluation of synthetic anti-HER2 Affibody molecules site-specifically labelled with 111In using N-terminal DOTA, NOTA and NODAGA chelators in mice bearing prostate cancer xenografts.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39, Issue:3

    Topics: Acetates; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Isotope Labeling; Male; Mice; Molecular Imaging; Molecular Sequence Data; Prostatic Neoplasms; Receptor, ErbB-2; Substrate Specificity

2012
Comparison of mAbs targeting epithelial cell adhesion molecule for the detection of prostate cancer lymph node metastases with multimodal contrast agents: quantitative small-animal PET/CT and NIRF.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens, Neoplasm; Binding, Competitive; Cell Adhesion Molecules; Cell Line, Tumor; Contrast Media; Copper Radioisotopes; Cross Reactions; Epithelial Cell Adhesion Molecule; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Immunoglobulin Fab Fragments; Infrared Rays; Lymphatic Metastasis; Male; Mice; Multimodal Imaging; Positron-Emission Tomography; Prostatic Neoplasms; ROC Curve; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tomography, X-Ray Computed

2012
44Sc-DOTA-BN[2-14]NH2 in comparison to 68Ga-DOTA-BN[2-14]NH2 in pre-clinical investigation. Is 44Sc a potential radionuclide for PET?
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2012, Volume: 70, Issue:12

    Topics: Animals; Bombesin; Cell Line, Tumor; Gallium Radioisotopes; Gastrin-Releasing Peptide; Heterocyclic Compounds, 1-Ring; Humans; Male; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Rats; Scandium; Tissue Distribution

2012
[99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours.
    European journal of nuclear medicine and molecular imaging, 2013, Volume: 40, Issue:3

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Stability; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Prostatic Neoplasms; Radionuclide Imaging; Receptor, IGF Type 1; Recombinant Fusion Proteins; Technetium

2013
Nanoparticle PET/CT imaging of natriuretic peptide clearance receptor in prostate cancer.
    Bioconjugate chemistry, 2013, Feb-20, Volume: 24, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Copper Radioisotopes; Heterocyclic Compounds, 1-Ring; Immunohistochemistry; Male; Mice; Mice, Nude; Nanoparticles; Positron-Emission Tomography; Prostate; Prostatic Neoplasms; Receptors, Atrial Natriuretic Factor

2013
cRGD peptide-conjugated icosahedral closo-B12(2-) core carrying multiple Gd3+-DOTA chelates for α(v)β3 integrin-targeted tumor imaging (MRI).
    Inorganic chemistry, 2013, Feb-18, Volume: 52, Issue:4

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Contrast Media; Gadolinium; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Male; Mice; Mice, SCID; Molecular Structure; Neoplasms, Experimental; Peptides, Cyclic; Prostatic Neoplasms; Vitamin B 12

2013
Enhanced therapeutic index of radioimmunotherapy (RIT) in prostate cancer patients: comparison of radiation dosimetry for 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)-peptide versus 2IT-DOTA monoclonal antibody linkage for RIT.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Sep-01, Volume: 9, Issue:10 Pt 2

    Topics: Antibodies, Monoclonal; Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Models, Chemical; Peptides; Prostatic Neoplasms; Radioimmunotherapy; Radiometry; Radiopharmaceuticals; Time Factors; Tissue Distribution; Treatment Outcome; Yttrium Radioisotopes

2003
Radioimmunotherapy of prostate cancer in human xenografts using monoclonal antibodies specific to prostate specific membrane antigen (PSMA): studies in nude mice.
    The Prostate, 2004, Feb-01, Volume: 58, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Chelating Agents; Glutamate Carboxypeptidase II; Heterocyclic Compounds, 1-Ring; Humans; Iodine Radioisotopes; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Prostatic Neoplasms; Radioimmunotherapy; Random Allocation; Survival Analysis; Transplantation, Heterologous; Yttrium Radioisotopes

2004
Evaluation of a cathepsin-cleavable peptide linked radioimmunoconjugate of a panadenocarcinoma MAb, m170, in mice and patients.
    Cancer biotherapy & radiopharmaceuticals, 2004, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Breast Neoplasms; Cathepsins; Chelating Agents; Female; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Indium Radioisotopes; Liver; Male; Mice; Mice, Nude; Peptides; Prostatic Neoplasms

2004
Does paclitaxel (Taxol) given after (111)In-labeled monoclonal antibodies increase tumor-cumulated activity in epithelial cancers?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Female; Heterocyclic Compounds, 1-Ring; Humans; Immunoglobulin G; Indium Radioisotopes; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms, Glandular and Epithelial; Paclitaxel; Prostatic Neoplasms; Radioimmunotherapy; Time Factors

2005
In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3.
    Cancer research, 2006, Oct-01, Volume: 66, Issue:19

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Female; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Integrin alphaVbeta3; Male; Mice; Mice, Nude; Neoplasm Proteins; Organometallic Compounds; Positron-Emission Tomography; Prostatic Neoplasms; Radiography; Radioimmunodetection; Radiometry; Tissue Distribution

2006
DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours.
    European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:8

    Topics: Animals; Bombesin; Cell Line, Tumor; Gallium Radioisotopes; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Radioisotopes; Radionuclide Imaging; Receptors, Bombesin

2007
In vivo evaluation and small-animal PET/CT of a prostate cancer mouse model using 64Cu bombesin analogs: side-by-side comparison of the CB-TE2A and DOTA chelation systems.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:8

    Topics: Animals; Bombesin; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Female; Heterocyclic Compounds, 1-Ring; Isotope Labeling; Male; Mice; Mice, Inbred ICR; Mice, SCID; Organometallic Compounds; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tomography, X-Ray Computed

2007
Value of apoptin's 40-amino-acid C-terminal fragment for the differentiation between human tumor and non-tumor cells.
    Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:4

    Topics: Amino Acid Sequence; Apoptosis; Astrocytes; Brain; Capsid Proteins; Cell Line, Tumor; Cell Nucleus; Cells, Cultured; Dansyl Compounds; Flow Cytometry; Fluorescein-5-isothiocyanate; Glioma; Heterocyclic Compounds, 1-Ring; Humans; Male; Microscopy, Confocal; Microscopy, Fluorescence; Nuclear Export Signals; Nuclear Localization Signals; Peptide Fragments; Phosphothreonine; Prostate; Prostatic Neoplasms; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium

2008
Tumor therapy with targeted atomic nanogenerators.
    Science (New York, N.Y.), 2001, Nov-16, Volume: 294, Issue:5546

    Topics: Actinium; Alpha Particles; Animals; Antibodies, Monoclonal; Female; Half-Life; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Linear Energy Transfer; Lymphoma; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Prostate-Specific Antigen; Prostatic Neoplasms; Radioimmunotherapy; Survival Rate; Tumor Cells, Cultured

2001
Pm-149 DOTA bombesin analogs for potential radiotherapy. in vivo comparison with Sm-153 and Lu-177 labeled DO3A-amide-betaAla-BBN(7-14)NH(2).
    Nuclear medicine and biology, 2002, Volume: 29, Issue:4

    Topics: Animals; Bombesin; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Metabolic Clearance Rate; Metals, Rare Earth; Mice; Peptide Fragments; Promethium; Prostatic Neoplasms; Radiopharmaceuticals; Reproducibility of Results; Samarium; Sensitivity and Specificity; Tissue Distribution

2002