1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid has been researched along with Neoplasms in 77 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (2.60) | 18.2507 |
2000's | 27 (35.06) | 29.6817 |
2010's | 42 (54.55) | 24.3611 |
2020's | 6 (7.79) | 2.80 |
Authors | Studies |
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Baradaran, S; Sadeghi, M; Saeedzadeh, E; Sahafi-Pour, SA; Shirmardi, SP | 1 |
Almasi, CE; Bentestuen, M; Gossili, F; Zacho, HD | 1 |
Ematsu, Y; Fuchigami, T; Hirose, K; Imai, S; Kinuya, S; Mishiro, K; Munekane, M; Ogawa, K | 1 |
Abedi, SM; Hosseinimehr, SJ; Khorramimoghaddam, A; Molavipordanjani, S; Mousavi, T; Talebpour Amiri, F | 1 |
Rustagi, V; Udugamasooriya, DG | 1 |
Costa, PF; Epple, M; Fendler, WP; Herrmann, K; Klose, J; Knuschke, T; Kollenda, SA; Schmitz, J; Sokolova, V; Staniszewska, M; Westendorf, AM | 1 |
Cao, Q; Huang, Q; Li, C; Wang, YA | 1 |
Copping, R; Johnson, FL; Kunkel, F; Lee, D; Li, M; Liu, D; McAlister, D; Menda, Y; Mirzadeh, S; Olewein, K; Quinn, TP; Schultz, MK; Zhang, X; Zimmerman, BE | 1 |
Andresen, TL; Eliasen, R; Fliedner, FP; Hansen, AE; Henriksen, JR; Jensen, AI; Kjær, A; Parhamifar, L; Severin, GW | 1 |
Aboagye, EO; Carroll, L; Cowell, S; Lavdas, I; Vilar, R | 1 |
Bu, W; Chen, X; Cui, Z; He, M; Liu, Y; Song, R; Tang, Z; Wu, H; Yao, Z; Zhang, H; Zhang, M | 1 |
Albertoni, C; Anastasi, AM; Battistuzzi, G; De Santis, R; Giannini, G; Leone, L; Milazzo, FM; Petronzelli, F; Rosi, A; Salvini, L; Tei, L | 1 |
Antoine, R; Besse, S; Chezal, JM; Dugourd, P; Janier, M; Kryza, D; Lux, F; Mignot, A; Miot-Noirault, E; Morlieras, J; Perriat, P; Redini, F; Sancey, L; Tillement, O; Truillet, C; Vidal, A | 1 |
Greguric, I; Howell, NR; Katsifis, AG; Lengkeek, NA; Oehlke, E; Pellegrini, PA; Shepherd, RK | 1 |
Bérubé-Lauzière, Y; Guérin, B; Klarskov, K; Lebel, R; Lecomte, R; Ranyuk, E; van Lier, JE | 1 |
Cescato, R; Gmeiner, P; Hübner, H; Kolesinska, B; Maschauer, S; Prante, O; Purkayastha, N; Reubi, JC; Seebach, D; Sparr, C; Waser, B; Yoshinari, T | 1 |
Cescato, R; Cordopatis, P; de Jong, M; Krenning, EP; Maina, T; Nock, BA; Reubi, JC; Tatsi, A; Waser, B | 1 |
Barnhart, TE; Cai, W; Chakravarty, R; Hernandez, R; Hong, H; Valdovinos, HF; Yang, Y | 1 |
Braun, F; Kolenc Peitl, P; Kroselj, M; Maecke, HR; Mansi, R; Reubi, JC; Sollner Dolenc, M; Tamma, M; Waser, B | 1 |
Arleth, L; Binderup, T; Elema, DR; Huda, P; Jensen, M; Kjær, A; Midtgaard, SR; Pedersen, MC | 1 |
Baker, JR; Bhattacharjee, S; Kotylar, A; Otis, JB; Wang, H; Wang, SH; Yin, A; Zong, H | 1 |
Ahn, H; Chung, YH; Han, EH; Kim, I; Lee, E; Min, JY; Ryu, J | 1 |
Cai, W; Chen, K; Chen, X; Li, ZB; Wang, H | 1 |
Beck-Sickinger, AG; Dinkelborg, L; Friebe, M; Khan, IU; Lehmann, L; Neundorf, I; Sieger, S; Zwanziger, D | 1 |
Czernin, J; Hildebrandt, IJ; McCoy, MR; Meares, C; Olafsen, T; Phelps, ME; Radu, C; Weber, WA; Wei, LH; Wu, AM | 1 |
de Jong, M; Mindt, TL; Müller, C; Schibli, R | 1 |
Heiskanen, T; Kairemo, K | 1 |
Chen, X; Kim, YS; Liu, S; Liu, Z; Shi, J; Zhai, S | 1 |
Cescato, R; Forrer, F; Kneifel, S; Maecke, HR; Mansi, R; Reubi, JC; Tamma, ML; Wang, X; Waser, B | 1 |
Hansson, M; Orlova, A; Rosik, D; Sandström, M; Sjöberg, A; Tolmachev, V; Wållberg, H; Wennborg, A | 1 |
Ellison, D; Finucane, C; Foster, JM; Mather, SJ; Matzow, T; Sosabowski, JK; Watson, SA | 1 |
Chen, K; Chen, X; Gao, J; Huang, J; Lee, S; Li, X; Wang, J; Xie, J | 1 |
Cheng, Z; Cochran, JR; Gambhir, SS; Jiang, L; Kimura, RH; Li, P; Liu, H; Miao, Z; Ren, G; Silverman, AP | 1 |
Cheng, Z; Cochran, JR; Gambhir, SS; Kimura, RH; Miao, Z | 1 |
Cheng, D; Dou, S; Hnatowich, DJ; Liang, M; Liu, G; Liu, X; Rusckowski, M; Wang, Y | 1 |
Accardo, A; Benedetti, E; Morelli, G; Morisco, A; Palumbo, R; Tesauro, D | 1 |
Ambrosini, V; Baum, RP; Bomanji, JB; Chiti, A; De Cristoforo, C; Fanti, S; Gabriel, M; Oyen, W; Papathanasiou, ND; Pepe, G; Virgolini, I | 1 |
Banerjee, S; Chakraborty, S; Das, T; Sarma, HD; Venakatesh, M | 1 |
Boturyn, D; Dumy, P; Fujibayashi, Y; Fukumura, T; Furukawa, T; Galibert, M; Jin, ZH; Saga, T | 1 |
Chung, JK; Jeong, JM; Ju, CH; Kim, YJ; Lee, DS; Lee, JY; Lee, MC; Lee, YS; Shetty, D | 1 |
Chen, X; Ma, Y; Niu, G; Ye, Y; Zhu, L | 1 |
De Silva, CR; Hruby, VJ; Josan, JS; Lynch, RM; Pagel, MD; Vagner, J; Yoo, B | 1 |
Boerman, OC; Dijkgraaf, I; Eek, A; Joosten, L; Liskamp, RM; Rijkers, DT; van der Wildt, B; Versluis, C; Yim, CB | 1 |
Brechbiel, MW; Yong, K | 1 |
Anderson, AL; Bading, JR; Carmichael, J; Colcher, D; Crow, D; Hudson, PJ; Leong, D; Li, L; Poku, E; Raubitschek, AA; Shively, JE; Turatti, F; Wheatcroft, D; Wheatcroft, MP; Yazaki, PJ | 1 |
Baum, RP; Rösch, F | 1 |
Cheng, Z; Fan, F; Kimura, R; Liu, H; Miao, Z; Zhang, X | 1 |
Alshoukr, F; Barbet, J; Brans, L; Gruaz-Guyon, A; Jallane, A; Mendes, S; Prignon, A; Talbot, JN; Tourwé, D | 1 |
Gandomkar, M; Maragheh, MG; Shamsaei, M; Shirmardi, SP | 1 |
Demmer, O; Gourni, E; Kessler, H; Schumacher, U; Wester, HJ | 1 |
Divilov, V; Hilderbrand, SA; Lewis, JS; Mohindra, P; Weissleder, R; Weissmann, GI; Zeglis, BM | 1 |
Cescato, R; Fani, M; Reubi, JC; Waser, B | 1 |
Hong, MK; Jeong, JM; Kim, SE; Kim, YJ; Lee, JJ; Lee, YS; Shetty, D; Son, JY | 1 |
Boswell, CA; Firestein, R; Fourie, A; Fuji, R; Gill, H; Khawli, LA; Kozak, KR; Lin, K; Ljumanovic, N; Mao, W; Mundo, EE; Polakis, P; Stainton, S; Ulufatu, S; Young, C; Zhang, C | 1 |
Chen, H; Li, Z; Luo, Q; Luo, Y; Wang, Q; Yan, X; Yang, L; Zhang, B; Zhang, Z | 1 |
Andersen, JT; Channappa, D; Chea, J; Cheung, CW; Colcher, D; Crow, D; Lee, B; Li, L; Orcutt, KD; Poku, E; Raubitschek, A; Sandlie, I; Shively, JE; Wittrup, KD; Yazaki, PJ | 1 |
Chelli, M; Chinol, M; De Luca, A; Ginanneschi, M; Leone, G; Paganelli, G; Papi, S; Papini, AM; Sabatino, G | 1 |
Areces, L; Bussolati, G; Cassoni, P; Chini, B; Chinol, M; Manning, M; Marrocco, T; Paganelli, G; Papi, S; Reversi, A | 1 |
Barrett, J; Bartis, J; Bozarth, J; Edwards, S; Ellars, C; Harris, TD; Kalogeropoulos, S; Lazewatsky, J; Liu, S; Nguyen, T; Onthank, D; Robinson, S; Silva, P; Yalamanchili, P | 1 |
Afroze, F; Akhurst, T; Larson, SM; Rosen, N; Smith-Jones, PM; Solit, DB | 1 |
Cavanaugh, SX; Hammond, LA; Thomas, CR | 1 |
Adamson, GN; DeNardo, GL; DeNardo, SJ; Foreman, AR; Gruettner, C; Ivkov, R; Miers, LA; Natarajan, A | 1 |
Amirkhanov, NV; Wickstrom, E | 1 |
Albert, R; Bruns, C; Hoyer, D; Kerrad, S; Kneuer, R; Lewis, I; Pless, J; Simeon, C | 1 |
Chu, DZ; Leong, L; Liu, A; Raubitschek, AA; Shively, JE; Wilczynski, S; Williams, LE; Wong, JY; Wu, AM; Yamauchi, DM; Yazaki, PJ; Zhan, J | 1 |
Mårtensson, L; Nilsson, R; Ohlsson, T; Sjögren, HO; Strand, SE; Tennvall, J | 1 |
Boerman, OC; Brouwer, AJ; Corstens, FH; Dechesne, AC; Dijkgraaf, I; Liskamp, RM; Rijkers, DT; Rijnders, AY; Soede, A; van Esse, GW | 1 |
Kessler, H; Knör, S; Modlinger, A; Poethko, T; Schottelius, M; Wester, HJ | 1 |
Reilly, RM | 1 |
Bartlett, DW; Davis, ME; Hildebrandt, IJ; Su, H; Weber, WA | 1 |
Fukase, K; Tanaka, K | 1 |
Anderson, CJ; Capretto, DA; Meyer, LA; Ping Li, W; Sherman, CD | 1 |
Chinol, M; Cremonesi, M; Ferrari, M; Grana, C; Paganelli, G; Prisco, G; Robertson, C; Stabin, MG; Tosi, G | 1 |
Cutler, CS; Deutsch, E; Ehrhardt, GJ; Jurisson, SS; Smith, CJ; Tyler, TT | 1 |
Bander, NH; Borchardt, P; Curcio, MJ; Frank, RK; Lai, LT; Ma, D; McDevitt, MR; Miederer, M; Pellegrini, V; Scheinberg, DA; Simon, J; Wu, K | 1 |
DeNardo, DG; DeNardo, GL; DeNardo, SJ; Shi, XB; Xiong, CY | 1 |
Courtenay-Luck, NS; Epenetos, AA; Gooden, CS; Kosmas, C; McCall, MJ; Meares, CF; Snook, D | 1 |
3 review(s) available for 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Neoplasms
Article | Year |
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Prevalence and significance of incidental findings on 68 Ga-DOTA-conjugated somatostatin receptor-targeting peptide PET/CT: a systematic review of the literature.
Topics: Heterocyclic Compounds, 1-Ring; Humans; Incidental Findings; Neoplasms; Peptides; Positron Emission Tomography Computed Tomography; Prevalence; Receptors, Somatostatin; Retrospective Studies | 2022 |
PET (positron emission tomography) imaging of biomolecules using metal-DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics.
Topics: Animals; Antibodies, Monoclonal; Antigens; Glycoproteins; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Metals; Neoplasms; Oligonucleotides; Organometallic Compounds; Peptides; Positron-Emission Tomography | 2008 |
Current and potential therapeutic uses of lanthanide radioisotopes.
Topics: Alpha Particles; Beta Particles; Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Metals, Rare Earth; Neoplasm Metastasis; Neoplasm Staging; Neoplasms; Peptide Fragments; Radioisotopes; Radionuclide Imaging; Receptors, Somatostatin; Technetium | 2000 |
3 trial(s) available for 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Neoplasms
Article | Year |
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A phase I trial of (90)Y-DOTA-anti-CEA chimeric T84.66 (cT84.66) radioimmunotherapy in patients with metastatic CEA-producing malignancies.
Topics: Adult; Aged; Antibodies, Monoclonal; Carcinoembryonic Antigen; Female; Heterocyclic Compounds, 1-Ring; Humans; Immunoglobulin G; Immunotoxins; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Radioimmunotherapy; Yttrium Radioisotopes | 2006 |
Three-step radioimmunotherapy with yttrium-90 biotin: dosimetry and pharmacokinetics in cancer patients.
Topics: Antibodies, Monoclonal; Avidin; Biotinylation; Bone Marrow; Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Kidney; Liver; Models, Biological; Neoplasms; Pentetic Acid; Radioimmunotherapy; Radiopharmaceuticals; Radiotherapy Dosage; Streptavidin; Tomography, Emission-Computed; Urinary Bladder; Whole-Body Counting; Yttrium Radioisotopes | 1999 |
Development of humoral immune responses against a macrocyclic chelating agent (DOTA) in cancer patients receiving radioimmunoconjugates for imaging and therapy.
Topics: Aged; Antibodies; Antibodies, Monoclonal; Antibody Formation; Breast; Breast Neoplasms; Chelating Agents; Drug Evaluation; Female; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Middle Aged; Neoplasm Staging; Neoplasms; Ovarian Neoplasms; Radioimmunotherapy; Radionuclide Imaging; Stomach Neoplasms; Testicular Neoplasms; Yttrium Radioisotopes | 1992 |
71 other study(ies) available for 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid and Neoplasms
Article | Year |
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Internal dosimetry studies of
Topics: Animals; gamma-Aminobutyric Acid; Heterocyclic Compounds, 1-Ring; Humans; Male; Monte Carlo Method; Neoplasms; Radiometry; Radiopharmaceuticals | 2022 |
RGD Peptide-Conjugated Dodecaborate with the Ga-DOTA Complex: A Preliminary Study for the Development of Theranostic Agents for Boron Neutron Capture Therapy and Its Companion Diagnostics.
Topics: Albumins; Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Iodine Radioisotopes; Mice; Neoplasms; Precision Medicine; Tissue Distribution | 2022 |
The preclinical study of
Topics: Animals; Cell Line, Tumor; Humans; Lutetium; Mice; Mice, Nude; Neoplasms; Radiopharmaceuticals; Tissue Distribution | 2023 |
Identification of side arm-modified DOTA scaffolds as multi-site binding ligands for cancer cells over normal cells.
Topics: Bronchi; Cells, Cultured; Chelating Agents; Epithelial Cells; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Molecular Structure; Neoplasms; Positron-Emission Tomography; Small Molecule Libraries | 2019 |
In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CT.
Topics: Animals; Calcium Phosphates; Cell Line, Tumor; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Injections, Intramuscular; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Positron Emission Tomography Computed Tomography | 2020 |
Abraxane-induced bone marrow CD11b
Topics: Albumin-Bound Paclitaxel; Animals; Antibodies; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; CD11b Antigen; Cell Line, Tumor; Copper Radioisotopes; Female; Gene Expression; Heterocyclic Compounds, 1-Ring; Heterografts; Humans; Macrophage Colony-Stimulating Factor; Mice; Mice, Nude; Myeloid Cells; Neoplasms; Organometallic Compounds; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Spleen; Tumor Microenvironment | 2021 |
Automated cassette-based production of high specific activity [
Topics: Animals; Chromatography, High Pressure Liquid; Heterocyclic Compounds, 1-Ring; Humans; Lead Radioisotopes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasms; Peptides; Radiopharmaceuticals; Radiotherapy, Image-Guided; Theranostic Nanomedicine; Tissue Distribution | 2017 |
Remote-loading of liposomes with manganese-52 and in vivo evaluation of the stabilities of
Topics: Animals; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Heterocyclic Compounds, 1-Ring; Liposomes; Manganese; Mice, Inbred BALB C; Neoplasms; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution | 2018 |
Towards an MMP-2-activated molecular agent for cancer imaging.
Topics: Amino Acid Sequence; Enzyme Activation; Gadolinium; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Magnetic Resonance Imaging; Matrix Metalloproteinase 2; Neoplasms; Organometallic Compounds; Peptides | 2018 |
A multifunctional nanotheranostic for the intelligent MRI diagnosis and synergistic treatment of hypoxic tumor.
Topics: Animals; Antineoplastic Agents; Cell Survival; Contrast Media; Doxorubicin; Drug Carriers; Female; HeLa Cells; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Manganese Compounds; Mice; Mice, Nude; Nanoparticles; Neoplasms; Oxides; Porosity; Silicon Dioxide; Theranostic Nanomedicine; Tumor Hypoxia | 2018 |
Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors.
Topics: Dose-Response Relationship, Drug; Heterocyclic Compounds, 1-Ring; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tenascin; Theranostic Nanomedicine | 2019 |
In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.
Topics: Animals; Contrast Media; Gadolinium; Heterocyclic Compounds, 1-Ring; Indium Radioisotopes; Isotope Labeling; Knee Joint; Nanoparticles; Neoplasms; Proteoglycans; Pyridinium Compounds; Quantum Dots; Quaternary Ammonium Compounds; Radionuclide Imaging; Rats | 2013 |
Synthesis and radiolabelling of DOTA-linked glutamine analogues with ⁶⁷,⁶⁸Ga as markers for increased glutamine metabolism in tumour cells.
Topics: Biomarkers; Cell Line, Tumor; Gallium Radioisotopes; Glutamine; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Neoplasms; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals | 2013 |
(68)Ga/DOTA- and (64)Cu/NOTA-phthalocyanine conjugates as fluorescent/PET bimodal imaging probes.
Topics: Animals; Copper Radioisotopes; Fluorescent Dyes; Gallium Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Indoles; Isoindoles; Mice; Mice, Nude; Neoplasms; Optical Imaging; Positron-Emission Tomography | 2013 |
Syntheses, receptor bindings, in vitro and in vivo stabilities and biodistributions of DOTA-neurotensin(8-13) derivatives containing β-amino acid residues - a lesson about the importance of animal experiments.
Topics: Animals; Binding Sites; Contrast Media; Coordination Complexes; Crystallography, X-Ray; Gadolinium; Heterocyclic Compounds, 1-Ring; HT29 Cells; Humans; Mice; Mice, Nude; Molecular Docking Simulation; Neoplasms; Neurotensin; Positron-Emission Tomography; Protein Structure, Tertiary; Receptors, Neurotensin; Tissue Distribution; Transplantation, Heterologous | 2013 |
[DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting.
Topics: Animals; Autoradiography; Cell Line, Tumor; Drug Stability; HEK293 Cells; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Ligands; Mice; Mice, SCID; Microscopy, Fluorescence; Molecular Structure; Neoplasms; Protein Binding; Radiopharmaceuticals; Rats; Receptors, Somatostatin; Somatostatin; Structure-Activity Relationship; Tissue Distribution | 2014 |
(44)Sc: an attractive isotope for peptide-based PET imaging.
Topics: Amino Acid Motifs; Animals; Binding, Competitive; Calcium; Cell Line, Tumor; Disease Models, Animal; Heterocyclic Compounds, 1-Ring; Humans; Image Processing, Computer-Assisted; Inhibitory Concentration 50; Integrin alphaVbeta3; Mice; Molecular Imaging; Neoplasm Transplantation; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Radioisotopes; Scandium; Tissue Distribution | 2014 |
Stereochemistry of amino acid spacers determines the pharmacokinetics of (111)In-DOTA-minigastrin analogues for targeting the CCK2/gastrin receptor.
Topics: Amino Acid Sequence; Animals; Gastrins; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Male; Neoplasms; Positron-Emission Tomography; Rats, Inbred Lew; Receptor, Cholecystokinin B | 2015 |
PET/CT Based In Vivo Evaluation of 64Cu Labelled Nanodiscs in Tumor Bearing Mice.
Topics: Animals; Cell Line, Tumor; Copper Radioisotopes; Disease Models, Animal; Heterocyclic Compounds, 1-Ring; Heterografts; Humans; Mice; Nanostructures; Neoplasms; Particle Size; Phosphatidylcholines; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Tomography, X-Ray Computed | 2015 |
Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells.
Topics: A549 Cells; Cell Line, Tumor; Cell Tracking; Dendrimers; Heterocyclic Compounds, 1-Ring; Humans; Metal Nanoparticles; Microscopy, Confocal; Neoplasms; Receptor, ErbB-2; Trastuzumab | 2016 |
One-Dimensional Supramolecular Nanoplatforms for Theranostics Based on Co-Assembly of Peptide Amphiphiles.
Topics: Doxorubicin; Gene Transfer Techniques; Heterocyclic Compounds, 1-Ring; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Imaging; MCF-7 Cells; Nanoparticles; Neoplasms; Peptides; Solutions; Surface-Active Agents; Theranostic Nanomedicine; Water | 2016 |
Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots.
Topics: Amines; Animals; Chelating Agents; Copper Radioisotopes; Fluorescence; Fluorescent Antibody Technique; Fluorescent Dyes; Frozen Sections; Heterocyclic Compounds, 1-Ring; Humans; Infrared Rays; Mice; Neoplasms; Positron-Emission Tomography; Quantum Dots; Rats; Receptors, Vascular Endothelial Growth Factor; Staining and Labeling; Tomography, Optical; Vascular Endothelial Growth Factor A | 2008 |
Novel chemically modified analogues of neuropeptide Y for tumor targeting.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cattle; Cell Line; Cell Line, Tumor; Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Ligands; Mice; Neoplasms; Neuropeptide Y; Receptors, Neuropeptide Y; Staining and Labeling; Tissue Distribution | 2008 |
Engineered antibody fragments with infinite affinity as reporter genes for PET imaging.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Base Sequence; Cell Line, Tumor; Feasibility Studies; Gene Expression Regulation, Neoplastic; Genes, Reporter; Heterocyclic Compounds, 1-Ring; Humans; Immunoglobulin Fragments; Mice; Neoplasms; Positron-Emission Tomography; Protein Engineering; Substrate Specificity; Tissue Distribution; Yttrium | 2008 |
Evaluation of a novel radiofolate in tumour-bearing mice: promising prospects for folate-based radionuclide therapy.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Female; Folate Receptors, GPI-Anchored; Folic Acid; Heterocyclic Compounds, 1-Ring; Humans; Mice; Neoplasms; Radiopharmaceuticals; Receptors, Cell Surface; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2009 |
Development of a PBPK model for monoclonal antibodies and simulation of human and mice PBPK of a radiolabelled monoclonal antibody.
Topics: alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Computer Simulation; Drug Delivery Systems; Female; Heterocyclic Compounds, 1-Ring; Humans; Immunoglobulin G; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Models, Biological; Neoplasms; Permeability; Species Specificity; Tissue Distribution | 2009 |
Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers.
Topics: Animals; Copper Radioisotopes; Dimerization; Gene Expression Regulation, Neoplastic; Glioma; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Mice; Neoplasms; Oligopeptides; Peptides, Cyclic; Polyethylene Glycols; Positron-Emission Tomography; Radiochemistry; Staining and Labeling; Tissue Distribution; Transplantation, Heterologous | 2009 |
Evaluation of a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated bombesin-based radioantagonist for the labeling with single-photon emission computed tomography, positron emission tomography, and therapeutic radionuclides.
Topics: Animals; Bombesin; Cells, Cultured; Drug Delivery Systems; Female; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Mice; Mice, Nude; Models, Biological; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radioisotopes; Receptors, Bombesin; Receptors, G-Protein-Coupled; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous | 2009 |
Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: aspect of the injected tracer amount.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Transformation, Neoplastic; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Injections; Mice; Molecular Imaging; Neoplasms; Radioactive Tracers; Radionuclide Imaging; Recombinant Fusion Proteins; Substrate Specificity; Tissue Distribution | 2010 |
Targeting of CCK-2 receptor-expressing tumors using a radiolabeled divalent gastrin peptide.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Female; Gastrins; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Isotope Labeling; Mice; Neoplasms; Protein Stability; Protein Transport; Rats; Receptor, Cholecystokinin B; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2009 |
PET/NIRF/MRI triple functional iron oxide nanoparticles.
Topics: Animals; Biocompatible Materials; Carbocyanines; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Drug Carriers; Ferric Compounds; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Materials Testing; Metal Nanoparticles; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Neoplasms; Positron-Emission Tomography; Spectroscopy, Near-Infrared; Transplantation, Heterologous | 2010 |
Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin.
Topics: Agouti-Related Protein; Amino Acid Sequence; Animals; Cell Line, Tumor; Copper Radioisotopes; Drug Stability; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms; Peptides; Positron-Emission Tomography; Protein Engineering; Radiopharmaceuticals; Recombinant Proteins; Tissue Distribution; Transplantation, Heterologous | 2010 |
A dual-labeled knottin peptide for PET and near-infrared fluorescence imaging of integrin expression in living subjects.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Copper Radioisotopes; Cystine-Knot Miniproteins; Female; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Nude; Molecular Imaging; Molecular Structure; Neoplasms; Positron-Emission Tomography; Spectroscopy, Near-Infrared; Tissue Distribution | 2010 |
Multimodality nuclear and fluorescence tumor imaging in mice using a streptavidin nanoparticle.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Cell Nucleus; Female; Fluorescence; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasms; Organometallic Compounds; Streptavidin; Xenograft Model Antitumor Assays | 2010 |
Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells.
Topics: Amino Acid Sequence; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Drug Delivery Systems; Flow Cytometry; Heterocyclic Compounds, 1-Ring; Humans; Liposomes; Neoplasms; Peptides; Receptors, Cholecystokinin; Sincalide | 2011 |
Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE.
Topics: Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Image Interpretation, Computer-Assisted; Injections; Neoplasms; Octreotide; Positron-Emission Tomography; Quality Control; Research Design; Tomography, X-Ray Computed | 2010 |
A novel 177Lu-labeled porphyrin for possible use in targeted tumor therapy.
Topics: Animals; Chelating Agents; Cross-Linking Reagents; Female; Heterocyclic Compounds, 1-Ring; Lutetium; Mice; Neoplasms; Porphyrins; Radioisotopes; Radionuclide Imaging; Treatment Outcome | 2010 |
RGD-cyclam conjugate: synthesis and potential application for positron emission tomography.
Topics: Animals; Copper Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Mice; Mice, Nude; Neoplasms; Oligopeptides; Positron-Emission Tomography | 2010 |
Synthesis and evaluation of macrocyclic amino acid derivatives for tumor imaging by gallium-68 positron emission tomography.
Topics: Animals; Blood Proteins; Cell Line, Tumor; Chelating Agents; Gallium Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Mice; Neoplasms; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals | 2010 |
Synthesis and evaluation of new iRGD peptide analogs for tumor optical imaging.
Topics: Amino Acid Sequence; Animals; Fluorescent Dyes; Heterocyclic Compounds, 1-Ring; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasms; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Transplantation, Heterologous | 2011 |
Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.
Topics: Animals; Binding Sites; Cell Line; Chelating Agents; Fluorescent Dyes; Heterocyclic Compounds, 1-Ring; Humans; Lanthanoid Series Elements; Ligands; Magnetic Resonance Imaging; Mice; Microscopy, Fluorescence; Molecular Imaging; Neoplasms; Pentetic Acid | 2011 |
Spacer effects on in vivo properties of DOTA-conjugated dimeric [Tyr3]octreotate peptides synthesized by a "Cu(I)-click" and "sulfo-click" ligation method.
Topics: Animals; Cell Line, Tumor; Click Chemistry; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Peptides, Cyclic; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Rats; Receptors, Somatostatin | 2011 |
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
Topics: Alpha Particles; Coordination Complexes; Drug Evaluation, Preclinical; Heterocyclic Compounds, 1-Ring; Humans; Lead; Lead Radioisotopes; Linear Energy Transfer; Neoplasms; Radioimmunotherapy; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2011 |
Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging.
Topics: Animals; Binding Sites; Copper Radioisotopes; Female; Heterocyclic Compounds, 1-Ring; Kidney; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Neoplasms; Polyethylene Glycols; Positron-Emission Tomography; Radiopharmaceuticals; Sulfhydryl Compounds; Tissue Distribution | 2011 |
Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS.
Topics: Coordination Complexes; Heterocyclic Compounds, 1-Ring; Humans; Metals; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals | 2011 |
Macrocyclic chelator assembled RGD multimers for tumor targeting.
Topics: Animals; Chelating Agents; Diagnostic Imaging; Drug Delivery Systems; Heterocyclic Compounds, 1-Ring; Macrocyclic Compounds; Mice; Molecular Structure; Neoplasms; Oligopeptides | 2011 |
Novel DOTA-neurotensin analogues for 111In scintigraphy and 68Ga PET imaging of neurotensin receptor-positive tumors.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Female; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Mice; Mice, Inbred BALB C; Neoplasms; Positron-Emission Tomography; Receptors, Neurotensin | 2011 |
Preclinical evaluation of a new bombesin analog for imaging of gastrin-releasing peptide receptors.
Topics: Animals; Bombesin; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Gastrin-Releasing Peptide; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Chemical; Neoplasms; Peptides; Receptors, Bombesin; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2011 |
PET imaging of CXCR4 receptors in cancer by a new optimized ligand.
Topics: Animals; Cell Line, Tumor; Contrast Media; Coordination Complexes; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Mice; Mice, Nude; Neoplasms; Positron-Emission Tomography; Receptors, CXCR4; Structure-Activity Relationship; Tissue Distribution; Transplantation, Heterologous | 2011 |
Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry.
Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Click Chemistry; Female; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Nude; Neoplasms; Norbornanes; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, ErbB-2; Trastuzumab | 2011 |
Evaluation of 177Lu-DOTA-sst2 antagonist versus 177Lu-DOTA-sst2 agonist binding in human cancers in vitro.
Topics: Amino Acid Sequence; Autoradiography; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Lutetium; Neoplasms; Oligopeptides; Protein Binding; Radioisotopes; Receptors, Somatostatin | 2011 |
Evaluation of (111)In-labeled macrocyclic chelator-amino acid derivatives for cancer imaging.
Topics: Amino Acids; Aminobutyrates; Animals; Cell Line, Tumor; Chelating Agents; Glioma; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Mice; Mice, Nude; Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous | 2012 |
An integrated approach to identify normal tissue expression of targets for antibody-drug conjugates: case study of TENB2.
Topics: Animals; Antigens; Cell Line, Tumor; Cytotoxins; Heterocyclic Compounds, 1-Ring; Immunoconjugates; Male; Membrane Proteins; Mice; Mice, SCID; Neoplasm Proteins; Neoplasms; Oligopeptides; Pharmaceutical Preparations; Tissue Distribution | 2013 |
Integrin-targeted trifunctional probe for cancer cells: a "seeing and counting" approach.
Topics: Amides; Cell Count; Cell Line, Tumor; Drug Design; Europium; Fluorescein; Fluorescent Dyes; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Molecular Probes; Neoplasms; Oligopeptides | 2012 |
A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance.
Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Carcinoembryonic Antigen; Female; Heterocyclic Compounds, 1-Ring; Humans; Iodine Radioisotopes; Mice; Mice, Nude; Neoplasms; Protein Engineering; Protein Stability; Radioimmunotherapy; Single-Chain Antibodies; Tissue Distribution | 2013 |
A new biotin derivative-DOTA conjugate as a candidate for pretargeted diagnosis and therapy of tumors.
Topics: Antineoplastic Agents; Avidin; Biotin; Chelating Agents; Drug Stability; Heterocyclic Compounds, 1-Ring; Humans; Isotope Labeling; Neoplasms; Protein Binding; Radiopharmaceuticals; Yttrium | 2003 |
Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogue.
Topics: Animals; Breast Neoplasms; Carcinoma; Chelating Agents; COS Cells; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Isotope Labeling; Mice; Neoplasms; Oxytocin; Protein Binding; Radioactive Tracers; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Oxytocin; Sensitivity and Specificity; Stomach Neoplasms; Tissue Distribution; Transfection; Tumor Cells, Cultured; Vasotocin | 2003 |
Design, synthesis, and evaluation of radiolabeled integrin alpha v beta 3 receptor antagonists for tumor imaging and radiotherapy.
Topics: Adenocarcinoma; Animals; beta-Alanine; Binding, Competitive; Cell-Matrix Junctions; Dose-Response Relationship, Radiation; Drug Design; Female; Fibrinogen; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Integrin alpha5beta1; Integrin alphaVbeta3; Integrins; Jurkat Cells; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Neoplasms; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Radioisotopes; Radionuclide Imaging; Receptors, Vitronectin; Sulfonamides; Tissue Distribution; Vitronectin; Yttrium Radioisotopes | 2003 |
Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzoquinones; Blotting, Western; Cell Line, Tumor; Copper Radioisotopes; Female; Heterocyclic Compounds, 1-Ring; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Immunoglobulin Fab Fragments; Indium Radioisotopes; Isotope Labeling; Lactams, Macrocyclic; Mice; Mice, Nude; Molecular Probe Techniques; Neoplasms; Phosphatidylinositol 3-Kinases; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Receptor, ErbB-2; Rifabutin; Tissue Distribution; Trastuzumab; Xenograft Model Antitumor Assays | 2004 |
An image worth a thousand lives?
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzoquinones; Bibenzyls; Diagnostic Imaging; Down-Regulation; ErbB Receptors; Gefitinib; Heterocyclic Compounds, 1-Ring; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Magnetic Resonance Imaging; Molecular Probe Techniques; Mutation; Neoplasms; Phthalazines; Physiological Phenomena; Positron-Emission Tomography; Protein Binding; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptors, Vascular Endothelial Growth Factor; Rifabutin; Stilbenes; Tissue Distribution; Trastuzumab | 2004 |
Development of tumor targeting bioprobes ((111)In-chimeric L6 monoclonal antibody nanoparticles) for alternating magnetic field cancer therapy.
Topics: Animals; Antibodies, Monoclonal; Biosensing Techniques; Chelating Agents; Cohort Studies; Electromagnetic Fields; Heterocyclic Compounds, 1-Ring; Immunoconjugates; Indium Radioisotopes; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Neoplasms; Polyethylene Glycols; Radioimmunotherapy; Time Factors; Tissue Distribution | 2005 |
Synthesis of novel polydiamidopropanoate dendrimer PNA-peptide chimeras for non-invasive magnetic resonance imaging of cancer.
Topics: Base Sequence; Chelating Agents; Chromatography, High Pressure Liquid; Genes, ras; Heterocyclic Compounds, 1-Ring; Humans; Magnetic Resonance Imaging; Models, Chemical; Molecular Sequence Data; Neoplasms; Peptide Nucleic Acids; Peptides; Polymers; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2005 |
Medicinal chemistry of somatostatin analogs leading to the DTPA and DOTA conjugates of the multi-receptor-ligand SOM230.
Topics: Chelating Agents; Heterocyclic Compounds, 1-Ring; Humans; Hydroxyproline; Isotope Labeling; Neoplasms; Pentetic Acid; Receptors, Somatostatin; Somatostatin; Technology, Pharmaceutical; Urethane | 2005 |
Reduced myelotoxicity with sustained tumor concentration of radioimmunoconjugates in rats after extracorporeal depletion.
Topics: Adsorption; Animals; Antibodies, Monoclonal; Bone Marrow Diseases; Extracorporeal Circulation; Heterocyclic Compounds, 1-Ring; Immunoconjugates; Immunotoxins; Indium Radioisotopes; Neoplasm Transplantation; Neoplasms; Radiation Injuries; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred BN; Transplantation, Isogeneic | 2007 |
Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes.
Topics: Alkynes; Animals; Binding, Competitive; Dendrimers; Drug Delivery Systems; Female; Heterocyclic Compounds, 1-Ring; Humans; Imaging, Three-Dimensional; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasms; Peptides, Cyclic; Protein Binding; Tissue Distribution; Xenograft Model Antitumor Assays | 2007 |
Synthesis of novel 1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid (DOTA) derivatives for chemoselective attachment to unprotected polyfunctionalized compounds.
Topics: Alkynes; Amination; Animals; Azides; Carbonic Acid; Catalysis; Cell Line, Tumor; Chromatography, High Pressure Liquid; Copper; Cyclization; Female; Heterocyclic Compounds, 1-Ring; Ketones; Mice; Mice, Nude; Molecular Structure; Neoplasms; Oximes; Oxygen; Peptides; Rats; Tyrosine; Xenograft Model Antitumor Assays | 2007 |
Carbon nanotubes: potential benefits and risks of nanotechnology in nuclear medicine.
Topics: Antibodies; Cell Membrane Permeability; Chelating Agents; Drug Delivery Systems; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Lymphoma, B-Cell; Nanotubes, Carbon; Neoplasms; Radioimmunotherapy; Radiopharmaceuticals | 2007 |
Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging.
Topics: Animals; Chemistry, Pharmaceutical; Cyclodextrins; Drug Carriers; Drug Delivery Systems; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, SCID; Nanoparticles; Neoplasm Transplantation; Neoplasms; Positron-Emission Tomography; RNA, Small Interfering; Technology, Pharmaceutical | 2007 |
Receptor-binding, biodistribution, and metabolism studies of 64Cu-DOTA-cetuximab, a PET-imaging agent for epidermal growth-factor receptor-positive tumors.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cetuximab; Copper Radioisotopes; ErbB Receptors; Heterocyclic Compounds, 1-Ring; Humans; Immunotherapy; Mice; Mice, Nude; Neoplasms; Positron-Emission Tomography; Radiochemistry; Tissue Distribution; Xenograft Model Antitumor Assays | 2008 |
Tumor therapy with targeted atomic nanogenerators.
Topics: Actinium; Alpha Particles; Animals; Antibodies, Monoclonal; Female; Half-Life; Heterocyclic Compounds, 1-Ring; Humans; Immunoconjugates; Linear Energy Transfer; Lymphoma; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Prostate-Specific Antigen; Prostatic Neoplasms; Radioimmunotherapy; Survival Rate; Tumor Cells, Cultured | 2001 |
Anti-HLA-DR/anti-DOTA diabody construction in a modular gene design platform: bispecific antibodies for pretargeted radioimmunotherapy.
Topics: Antibodies, Bispecific; Antibodies, Monoclonal; Antibody Affinity; Bacteriophages; Blotting, Western; Chelating Agents; DNA Primers; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Gene Expression; Heterocyclic Compounds, 1-Ring; HLA-DR Antigens; Humans; Immunoglobulin Fc Fragments; Neoplasms; Peptide Library; Polymerase Chain Reaction; Radioimmunotherapy | 2001 |